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Design Factors and Criteria for Building a Non-Level Pedestrian Crossing at an Urban Campus 城市校园非水平人行横道的设计因素与标准
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12526
F. S. Pradifta, V. Damayanti, W. Weishaguna, W. R. S. Prayoga, A. A. Fadlimat
Bandung Islamic University (UNISBA) is in a densely populated urban area of Bandung. UNISBA lecture and administrative buildings are scattered in several locations. In architecture typo-morphology terms, a campus building with this environmental setting is often referred to as an urban campus. The high traffic flow on these roads, together with the intense conflict between road crossers, often results in congestion due to vehicle deceleration needed to allow pedestrian crossing. To facilitate the need for the movement for the users of the UNISBA campus buildings and minimize conflicts with road users, infrastructure that connects the UNISBA campus buildings is needed to facilitate pedestrian crossing. The pedestrian crossing could be in the form of a level crossing in the same elevation as the road or a non-level crossing situated above or under the road. The type of pedestrian crossing studied in this paper is a non-level pedestrian crossing in the form of a pedestrian bridge. In designing the infrastructure for non-level crossings, it is necessary to pay attention to the movement patterns that occur and the factors that influence willingness to use. This study aims to determine the movement pattern of UNISBA campus facility users consisting of students, lecturers, educational staff, and visitors by using quantitative origin-destination spatial analysis. Descriptive exploratory factor analysis was also used to determine the preferences of the users of the UNISBA campus buildings to use non-level crossings. The results of this analysis will be the basis for designing non-level accessibility between UNISBA campus buildings. Keywords: pedestrian crossing, pedestrian bridge, urban campus, urban design, urban mobiity
万隆伊斯兰大学(UNISBA)位于人口稠密的万隆市区。UNISBA的演讲楼和行政楼分散在几个地点。在建筑排版形态学术语中,具有这种环境设置的校园建筑通常被称为城市校园。这些道路上的高交通流量,加上过路人员之间的激烈冲突,往往导致车辆减速以允许行人过路。为了方便UNISBA校园建筑使用者的移动需求,并尽量减少与道路使用者的冲突,需要连接UNISBA校园建筑的基础设施,以方便行人穿过。人行横道可以采用与道路相同高度的平交道口形式,也可以采用位于道路上方或下方的非平交道口形式。本文研究的人行横道类型是人行天桥形式的非水平人行横道。在设计非平交道口基础设施时,有必要注意发生的运动模式和影响使用意愿的因素。本研究旨在通过定量的起源-目的地空间分析,确定UNISBA校园设施用户(包括学生、讲师、教育人员和访客)的运动模式。描述性探索性因素分析还用于确定UNISBA校园建筑用户使用非平交道口的偏好。这一分析的结果将成为设计UNISBA校园建筑之间非水平可达性的基础。关键词:人行横道;人行天桥;城市校园
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引用次数: 0
The Improvement of the Dissolution and Release Characteristics of Ibuprofen Suppository Through Inclusion Complexes with 包合物对布洛芬栓剂溶出释放特性的改善
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12535
F. Darusman, M. I. Septian, E. Kartadarma
Ibuprofen is classified as a BCS class II because of its low solubility and high permeability. Inclusion complex formation using β-cyclodextrin is one method to increase a drug’s solubility. In addition to the method of increasing the solubility, the choice of dosage form and route of administration has a big role in the success of therapy because it can increase the onset of action of drugs while avoiding side effects. Rectal suppositories can provide a faster antipyretic effect than oral preparations. The purpose of this study was to determine the effect of inclusion complexes formation with β-cyclodextrin in increasing the dissolution rate and release characteristics of ibuprofen suppositories. The suppository formulation used various concentrations of cetylalcohol to increase the consistency of the cocoa butter base. The release characteristics of ibuprofen in suppositories were evaluated, including, organoleptic, melting time, weight diversity, dissolution rate and dissolution efficiency, by comparing ibuprofen inclusion complex suppositories with β-cyclodextrin all three mole ratios, namely 1:1, 1:2 and 2:1, to pure ibuprofen suppositories. The inclusion complex of ibuprofen with β-cyclodextrin at a mole ratio of 2:1 showed to increase the solubility and dissolution rate of ibuprofen in suppositories with good physical and release characteristics. Keywords: ibuprofen, inclusion complexes, suppository
布洛芬因其低溶解度和高渗透性而被归类为BCS II类。利用β-环糊精形成包合物是提高药物溶解度的一种方法。除了增加溶解度的方法外,剂型和给药途径的选择对治疗的成功起着很大的作用,因为它可以增加药物的起效,同时避免副作用。直肠栓剂可以提供比口服制剂更快的解热效果。研究β-环糊精包合物对布洛芬栓剂溶出度和释放特性的影响。栓剂配方使用不同浓度的十六烷基醇来增加可可脂基础的稠度。通过将β-环糊精布洛芬包合栓剂与纯布洛芬栓剂的摩尔比分别为1:1、1:2和2:1,评价布洛芬在栓剂中的释放特性,包括感官、融化时间、重量多样性、溶出率和溶出效率。布洛芬与β-环糊精摩尔比为2:1的包合物提高了布洛芬在栓剂中的溶解度和溶出率,具有良好的物理特性和释放特性。关键词:布洛芬;包合物;栓剂
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引用次数: 0
The Correlation Between the Oviposition of Aedes Sp. and the Features of a House 伊蚊产卵与房屋特征的相关性研究
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12511
Ratna Dewi Indi Astuti, C. Tresnasari, Siti Annisa Devi Trusda
Aedes aegypti mosquitoes exhibit specific behavior when choosing their nest. This study was conducted on April 2021 and aimed to assess the correlation between the oviposition habit of female Aedes sp. and the features of a house in 34 adjacent houses in the Tamansari area. Ovitraps were placed indoors and outdoors at each house. The number of mosquitoes that laid eggs were estimated by dividing the number of eggs found in the ovitrap by the average number of eggs produced by female mosquitoes. Data about the features of the houses were obtained by observing the houses and interviewing the house owners. Results showed that 79.41% of the houses had the Aedes sp.’s egg in an ovitrap. There was a correlation between the number of indoor oviposition mosquitoes and the number of occupants (p=0.04; r=0.35). There was also a correlation between the number of outdoor oviposition mosquitoes and the ratio of the house’s area (m2) per number of occupants (p=0.03; r=0.36). We conclude that mosquitoes prefer to nest inside a house with a lot of occupants and prefer to nest outside a house that is spacious and has few residents. Keywords: aedes, house, oviposition
埃及伊蚊在选择巢穴时表现出特定的行为。本研究于2021年4月进行,旨在评估Tamansari地区34个相邻房屋中雌性伊蚊产卵习性与房屋特征之间的相关性。诱卵器分别放置于每间房屋的室内和室外。产卵的蚊子数量是通过将诱蚊器中发现的卵数除以雌蚊产卵的平均数量来估计的。通过对房屋的观察和对房主的访谈,获得了房屋的特征数据。结果显示,79.41%的房屋诱蚊器中有伊蚊卵。室内产卵蚊数与占用者数呈正相关(p=0.04;r = 0.35)。室外产卵蚊的数量与房屋面积/人数之比也存在相关性(p=0.03;r = 0.36)。我们得出结论,蚊子更喜欢在人多的房子里筑巢,更喜欢在人少的宽敞房子外面筑巢。关键词:伊蚊;巢;产卵
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引用次数: 0
Formulation of Natural, Antiseptic Liquid from Jujube Leaf Extract for Islamic Dead Body Bathing Procedures 配方天然,消毒液体从枣叶提取物的伊斯兰尸体沐浴程序
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12536
I. T. Maulana, F. Darusman, L. Mulqie, S. E. Priani, E. N. Maulidya
Ziziphus spina-christi L. or Jujube, is a plant that has many health benefits, containing metabolite compounds that act as an antibacterial agent such as alkaloids, flavonoids, saponins, tannins, and polyphenols. This study aimed to make a natural antiseptic liquid from Ziziphus spina-christi L. leaf extract used in Islamic Bathing Procedures for a corpse. The stages of this research included extraction, an assay of the extract’s antiseptic activity using the agar well diffusion method, formulating the antiseptic liquid, evaluating the antiseptic liquid, and examining the antiseptic properties of the liquid. Jujube leaf extract with a concentration of 10% was proven to have the best antibiotic properties with a very strong inhibition zone category. Antiseptic liquid formulations include extracts, DMDM hydantoin, Triethanolamine, and Aqua rose. The organoleptic evaluation results of liquid antiseptic were in the form of a homogeneous concentrate liquid, brown with a rose aroma, pH 9.048, the density of 1.020 g/mL, viscosity of 5.60 m.Pas, and 0.7 cm high foam with high foam stability of 83.33%. The antiseptic test results showed that the antiseptic solution was able to inhibit the growth of Escherichia coli, Staphylococcus epidermidis, and Candida albicans ranging from strong to very strong inhibition zone diameters, 17.35 mm, 21.10 mm, and 19.95 mm, respectively. Keywords: antiseptic, antimicrobial, corpse bathing, jujube leaf (ziziphus spina christi L.)
红枣是一种对健康有益的植物,它含有代谢物化合物,可以作为抗菌剂,如生物碱、类黄酮、皂苷、单宁和多酚。本研究旨在从伊斯兰教尸体沐浴程序中使用的酸枣叶提取物中制备一种天然防腐液。本研究的阶段包括提取,使用琼脂孔扩散法测定提取物的防腐活性,配制防腐液,评估防腐液,检查液体的防腐性能。结果表明,浓度为10%的红枣叶提取物抗菌性能最好,抑菌带非常强。防腐液配方包括萃取物、DMDM氢妥英、三乙醇胺和玫瑰水。液体防腐剂的感官评价结果为均匀浓缩液体,呈棕色,具有玫瑰香气,pH为9.048,密度为1.020 g/mL,粘度为5.60 m。0.7 cm高泡沫,泡沫稳定性高达83.33%。抑菌试验结果表明,该抑菌液对大肠杆菌、表皮葡萄球菌和白色念珠菌的抑菌带直径分别为17.35 mm、21.10 mm和19.95 mm,抑菌带范围为强至极强。关键词:防腐,抗菌,尸浴,枣叶
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引用次数: 0
The Effects of Sugar, Blanching, and Pasteurization on the Antioxidant Properties of Pineapple Juice 糖、烫烫和巴氏杀菌对菠萝汁抗氧化性能的影响
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12507
Indra Topik Maulana, Budi Prabowo Soewondo, Radian ., Robby Prayitno, Winda Amelya
This study aimed to improve the quality of pineapple juice by increasing its durability and antioxidant properties. A factorial design with four test factors, namely, the level of ripeness of pineapple, sugar composition, duration of blanching, and pasteurization was used. The results showed that the use of ripe pineapple as an ingredient of pineapple juice had better responses than raw pineapple. The sugar composition had a negative response to the antioxidant property of pineapple juice, both measured on day 0 and day 7. The duration of blanching was proven to have a positive effect on increasing antioxidant activity both on day 0 and day 14. Pasteurization had a negative response when measured on day 0, and a positive response on day 14. Producing pineapple juice in accordance with the results has been proven to have greater durability and antioxidant properties. Keywords: blanching, pasteurization, pineapple juice, response surface methodology
本研究旨在通过提高菠萝汁的耐久度和抗氧化性能来改善菠萝汁的品质。采用四因素析因设计,即菠萝的成熟程度、糖成分、焯水时间和巴氏杀菌。结果表明,用成熟菠萝作为菠萝汁的原料比生菠萝有更好的反应。在第0天和第7天,糖组成对菠萝汁的抗氧化性能都有负响应。烫烫时间对第0天和第14天的抗氧化活性均有积极影响。巴氏灭菌在第0天有负反应,在第14天有正反应。根据实验结果生产的菠萝汁已被证明具有更强的耐久性和抗氧化性。关键词:焯水,巴氏杀菌,菠萝汁,响应面法
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引用次数: 0
The Effect of Aqueous Extract of Robusta Coffee Compared to Neomycin-Bacitracin on Wound Healing by Measuring TNF-1 and bFGF in Fibroblast Cell Cultures 通过测定成纤维细胞培养物中TNF-1和bFGF,对比罗布斯塔咖啡水提物与新霉素-杆菌肽对伤口愈合的影响
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12519
H. S. Yuwono, M. Putri, W. Purbaningsih, N. M. Marsya, S. A. Sumantri
Coffee grounds have been used to dress wounds for more than 100 years, with excellent results. The wound heals with an acceptable scar. This study aims to compare coffee extract to neomycin-bacitracin in cell migration. Compared to the antibiotic neomycin-bacitracin powder group and control group in scar tissue formation, the Robusta coffee powder extract measured positively on Transforming Growth Factor and Basic Fibroblast Growth Factor markers. This study emphasizes the ability of coffee to heal wounds without causing excessive scarring. Coffee is proven to have better wound healing capabilities than Neomycin-Bacitracin. Keywords: coffee grounds, fibroblast cell-line, Transforming Growth Factor, basic Fibroblast Growth Factor
100多年来,咖啡渣一直被用来包扎伤口,效果非常好。伤口愈合后留下可接受的疤痕。本研究旨在比较咖啡提取物和新霉素-杆菌肽对细胞迁移的影响。与抗生素新霉素-杆菌肽粉组和对照组相比,罗布斯塔咖啡粉提取物在疤痕组织形成中的转化生长因子和碱性成纤维细胞生长因子指标呈阳性。这项研究强调了咖啡在不造成过多疤痕的情况下治愈伤口的能力。咖啡被证明比新霉素-杆菌肽有更好的伤口愈合能力。关键词:咖啡渣,成纤维细胞,转化生长因子,碱性成纤维细胞生长因子
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引用次数: 1
The Development of Modular and Re-Usable Face Shields for COVID- 19 Prevention in Clinics 用于临床预防COVID- 19的模块化和可重复使用面罩的开发
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12533
F. A. Yulianto, A. Nurrahman, Y. S. Rejeki, N. R. As'ad, E. Amrullah, M. Nurhalim, M. A. Shakira, M. M. Ibrahim
COVID-19 continues to cause a high fatality rate - especially in health workers. Safety protocols in nearly all aspects of our lives were announced to minimize the spread of the disease. A common personal protection equipment (PPE) that is used as a safety precaution is the face shield, a portable barrier to protect human to human transmission. Unfortunately, this simple, mass-produced device has not been made in a standardized way. This study aimed to create a standard modular and ergonomic face shield that can be dispatched, recleaning, sterilized, and partially renewed. Polyethylene Terephthalate (PET) and Polylactide (PLA) filaments were selected as the materials to be used. PETs with 0.3 mm thickness were used for the visor. The headband was designed in AutoCAD 2019 then produced by a Flashforge 3D printer. Nurses’ anthropometric measurement was used as guidance in formulating the size of the head band. 60 head bands were produced in 2 months of 5 working days (80 minutes for each headband). This device was given to non-government clinics that have short PPE supplies and was evaluated according to their reliability and comfort. We concluded that this new PPE had minimum visual distortion, was easy to dismount, and easy to replace, except for the headband. Keywords: covid-19, face shield, prevention
COVID-19继续造成高死亡率,特别是在卫生工作者中。在我们生活的几乎所有方面都宣布了安全协议,以尽量减少疾病的传播。作为安全预防措施的一种常见个人防护装备是面罩,这是一种保护人与人之间传播的便携式屏障。不幸的是,这种简单的、批量生产的设备并没有以标准化的方式制造出来。本研究旨在创造一种标准的模块化和符合人体工程学的面罩,可以分发,清洁,消毒和部分更新。选用聚对苯二甲酸乙二醇酯(PET)和聚乳酸(PLA)长丝作为材料。遮阳板采用0.3 mm厚度的pet。头带是在AutoCAD 2019中设计的,然后由Flashforge 3D打印机生产。采用护士的人体测量作为制定头带尺寸的指导。2个月5个工作日生产60个头带(每个头带80分钟)。该设备已提供给个人防护用品短缺的非政府诊所,并根据其可靠性和舒适度进行了评估。我们的结论是,这种新的PPE具有最小的视觉失真,易于拆卸,易于更换,除了头带。关键词:新型冠状病毒,面罩,预防
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引用次数: 0
Validity and Reliability of a Questionnaire About Dental and Oral Health 口腔健康问卷的效度和信度
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12505
Y. Yuniarti, Caecielia Makaginsar, Siska Nia Irasanti, Fajar Awalia Yulianto
Knowledge about dental and oral health is one of the factors that influence the occurrence of various dental and oral complaints. Lack of knowledge about the importance of dental and oral care can lead to individuals neglecting dental and oral hygiene. To measure knowledge about dental and oral health, a questionnaire that has been tested and is ready for use is needed. This study aims to test the validity and reliability of a questionnaire about dental and oral health. A random sample of 29 people were selected to complete the questionnaire. The validity test used the Kappa coefficient, and the reliability test used the Cronbach alpha test. The results showed that of the 25 questions tested, 25 questions were valid, and 5 questions were reliable. In conclusion, the questionnaire needs to be reviewed in terms of sentence structure by experts in dentistry, so the questionnaire is easily understood by respondents. Keywords: validity, reability, questionnaire
牙齿和口腔健康知识是影响各种牙齿和口腔疾病发生的因素之一。缺乏对牙齿和口腔保健重要性的认识会导致人们忽视牙齿和口腔卫生。为了测量有关牙齿和口腔健康的知识,需要一份经过测试并准备使用的问卷。本研究旨在检验一份口腔健康问卷的效度与信度。随机抽取29人完成问卷调查。效度检验采用Kappa系数,信度检验采用Cronbach alpha检验。结果表明,在25个被测问题中,有效问题25个,可靠问题5个。综上所述,问卷需要牙科专家对句子结构进行审核,便于被调查者理解。关键词:效度,信度,问卷
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引用次数: 0
Criteria for the Development and Evaluation of the Implementation of a Sustainable Pedestrian Bridge 可持续人行天桥的开发和实施评价标准
Pub Date : 2022-12-27 DOI: 10.18502/kls.v7i5.12524
H. Hendrawan, S. Amelia
The Pedestrian Bridge (Indonesian: JPO) is a vital facility to reduce traffic conflicts and accidents. There is a need to optimize the use of JPO while encouraging sustainable infrastructure development. This requires sustainability criteria. This study aimed to develop and evaluate the implementation of a sustainable JPO criteria in Indonesia by constructing an ”eco JPO” prototype in Surakarta City. A qualitative and quantitative descriptive questionnaire instrument in the form of a Likert scale was used, and further analysis was done using interest performance analysis. The results showed that two criteria must be met, namely, planning criteria and design criteria. Planning criteria included suitability to people’s needs and location. The design criteria included seven measures: attractive design, environmentally friendly, energy self-sufficient, safe, artistic, comfortable, and safe. Based on the evaluation of the design criteria, the overall JPO criteria relatively had the same importance value, namely ”important” with values between 4.47 - 4.85, and weights between 5.8% - 6.57%. The satisfaction aspect showed a somewhat similar value, namely ”satisfied” with the grade between 3.67 - 4.61, and weights between 5.45% - 6.73%. Keywords: Sustainable, pedestrian bridge, criteria
人行天桥(印尼语:JPO)是减少交通冲突和事故的重要设施。在鼓励可持续基础设施发展的同时,有必要优化利用联合项目管理处。这需要可持续性标准。本研究旨在通过在泗水市建立一个“生态JPO”原型,开发和评估印度尼西亚可持续JPO标准的实施情况。采用李克特量表形式的定性和定量描述性问卷调查工具,并使用兴趣绩效分析进行进一步分析。结果表明,必须满足规划标准和设计标准两个标准。规划标准包括适合人们的需要和位置。设计标准包括7项指标:吸引人的设计、环保、能源自给、安全、艺术、舒适、安全。通过对各设计准则的评价,JPO各设计准则的重要性值相对相同,即“重要”,重要性值在4.47 ~ 4.85之间,权重在5.8% ~ 6.57%之间。满意度方面表现出类似的值,即“满意”的等级在3.67 - 4.61之间,权重在5.45% - 6.73%之间。关键词:可持续,人行天桥,标准
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引用次数: 0
Comparison Between Different Herbal Formulations of Roses and Their Therapeutic Potential 玫瑰不同草药配方的比较及其治疗潜力
Pub Date : 2022-12-16 DOI: 10.18502/kls.v7i5.12531
Santun Bhekti Rahimah, H. S. Sastramihardja, Miranti Kania Dewi, Y. Andriane, Annisa Devi Trusda
Roses are one of the most popular flowers in the world, not only because of their beauty but also because they have medicinal properties. Drugs developed from roses must be support from various parties. Roses have active components that can be used to improve public health, such as anthocyanins, tannins and other active compounds. Making the right rose water herbal mixtures will help filter out the active substances according to the expected therapeutic effect. The manufacture of herbal mixtures of roses can vary, namely, infusions, extracts and rose oil. These three variations require different procedures. The three herbal formulations can provide an initial condition of the content of the active substances in the roses. The results of the rose infusion gave a red color in a short time, while the maceration of the extract with ethyl alcohol, methanol and hexsan gave a varied color appearance, while the identification of rose oil using water distillation did not show any filtered oil. The comparison of the three preparations shows that the herbal formulations can be done in a simple way and the formulation that gives the best results is rose water infusions that produces rose water. Keywords: herbal preparation, rose infusion, rose oil, rose extract
玫瑰是世界上最受欢迎的花之一,不仅因为它们美丽,还因为它们具有药用价值。从玫瑰中开发药物必须得到各方的支持。玫瑰含有可用于改善公众健康的活性成分,如花青素、单宁和其他活性化合物。制作正确的玫瑰水草药混合物将有助于根据预期的治疗效果过滤出活性物质。玫瑰草药混合物的制造可以有所不同,即,浸剂,提取物和玫瑰油。这三种变化需要不同的程序。这三种草药制剂可以提供玫瑰中活性物质含量的初始条件。玫瑰浸渍的结果在短时间内呈现出红色,而用乙醇、甲醇和hexsan浸渍的提取物呈现出不同的颜色,而用水蒸馏法鉴定玫瑰精油没有显示出任何过滤过的油。三种制剂的比较表明,草药配方可以用一种简单的方法来完成,而效果最好的配方是玫瑰水冲剂,它可以产生玫瑰水。关键词:中药制剂,玫瑰浸膏,玫瑰精油,玫瑰提取物
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引用次数: 0
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KnE Life Sciences
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