Pub Date : 2024-09-03DOI: 10.1038/s41377-024-01586-z
Yongkang Zhang, Jie Zheng, Fangzhou Jin, Jie Xiao, Ni Lan, Zhiyuan Xu, Xu Yue, Zesen Li, Chengzhi Li, Donglin Cao, Yifei Wang, Wenbin Zhong, Yang Ran, Bai-Ou Guan
Chemotherapy is one of the conventional treatments for cancer in clinical practice. However, poor delivery efficiency, systemic toxicity, and the lack of pharmacokinetic monitoring during treatment are the critical limitations of current chemotherapy. Herein, we reported a brand-new antitumor drug delivery strategy that harnesses an optical fiber endoscopically therapeutic probe. The fiber probe carries photosensitizers in the fiber core and antitumor agents on the fiber surface mediated by a temperature-responsive hydrogel film, giving rise to an activable photothermal-chemotherapy that orchestrates the localized hyperthermia and thermal-stimuli drug release to the tumor lesion. Furthermore, the dynamical drug release and in-situ temperature can be real-time supervised through the built-in fiber sensors, including the reflective Mach–Zehnder interferometer and fiber Bragg grating, to visualize the therapy process and thus improve the safety of treatment. Compared with conventional methods, the fiber-optic drug delivery can adequately take advantage of the chemotherapeutics through collaboratively recruiting the photoheating-mediated enhanced permeability and the hydrogel particle-assisted high drug retention, shedding new light on a “central-to-peripheral” drug pervasion and retention mechanism to destroy tumors completely. The fiber-optic chemotherapy strategy incorporates precise drug delivery, accurate controllability of drug release, high drug permeability and retention in tumor, low off-target rate, and real-time drug release and temperature feedback, performing a straightforward and precise photothermal-chemotherapy pathway. More than that, the proposed strategy holds tremendous promise to provide a revolutionized on-demand drug delivery platform for the highly efficient evaluation and screening of antitumor pharmaceuticals.
{"title":"Fiber-optic drug delivery strategy for synergistic cancer photothermal-chemotherapy","authors":"Yongkang Zhang, Jie Zheng, Fangzhou Jin, Jie Xiao, Ni Lan, Zhiyuan Xu, Xu Yue, Zesen Li, Chengzhi Li, Donglin Cao, Yifei Wang, Wenbin Zhong, Yang Ran, Bai-Ou Guan","doi":"10.1038/s41377-024-01586-z","DOIUrl":"https://doi.org/10.1038/s41377-024-01586-z","url":null,"abstract":"<p>Chemotherapy is one of the conventional treatments for cancer in clinical practice. However, poor delivery efficiency, systemic toxicity, and the lack of pharmacokinetic monitoring during treatment are the critical limitations of current chemotherapy. Herein, we reported a brand-new antitumor drug delivery strategy that harnesses an optical fiber endoscopically therapeutic probe. The fiber probe carries photosensitizers in the fiber core and antitumor agents on the fiber surface mediated by a temperature-responsive hydrogel film, giving rise to an activable photothermal-chemotherapy that orchestrates the localized hyperthermia and thermal-stimuli drug release to the tumor lesion. Furthermore, the dynamical drug release and in-situ temperature can be real-time supervised through the built-in fiber sensors, including the reflective Mach–Zehnder interferometer and fiber Bragg grating, to visualize the therapy process and thus improve the safety of treatment. Compared with conventional methods, the fiber-optic drug delivery can adequately take advantage of the chemotherapeutics through collaboratively recruiting the photoheating-mediated enhanced permeability and the hydrogel particle-assisted high drug retention, shedding new light on a “central-to-peripheral” drug pervasion and retention mechanism to destroy tumors completely. The fiber-optic chemotherapy strategy incorporates precise drug delivery, accurate controllability of drug release, high drug permeability and retention in tumor, low off-target rate, and real-time drug release and temperature feedback, performing a straightforward and precise photothermal-chemotherapy pathway. More than that, the proposed strategy holds tremendous promise to provide a revolutionized on-demand drug delivery platform for the highly efficient evaluation and screening of antitumor pharmaceuticals.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142123451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-03DOI: 10.1038/s41377-024-01461-x
Chuang Yang, Wenjing Hu, Jiale Liu, Chuanzhou Han, Qiaojiao Gao, Anyi Mei, Yinhua Zhou, Fengwan Guo, Hongwei Han
In just over a decade, certified single-junction perovskite solar cells (PSCs) boast an impressive power conversion efficiency (PCE) of 26.1%. Such outstanding performance makes it highly viable for further development. Here, we have meticulously outlined challenges that arose during the industrialization of PSCs and proposed their corresponding solutions based on extensive research. We discussed the main challenges in this field including technological limitations, multi-scenario applications, sustainable development, etc. Mature photovoltaic solutions provide the perovskite community with invaluable insights for overcoming the challenges of industrialization. In the upcoming stages of PSCs advancement, it has become evident that addressing the challenges concerning long-term stability and sustainability is paramount. In this manner, we can facilitate a more effective integration of PSCs into our daily lives.
{"title":"Achievements, challenges, and future prospects for industrialization of perovskite solar cells","authors":"Chuang Yang, Wenjing Hu, Jiale Liu, Chuanzhou Han, Qiaojiao Gao, Anyi Mei, Yinhua Zhou, Fengwan Guo, Hongwei Han","doi":"10.1038/s41377-024-01461-x","DOIUrl":"https://doi.org/10.1038/s41377-024-01461-x","url":null,"abstract":"<p>In just over a decade, certified single-junction perovskite solar cells (PSCs) boast an impressive power conversion efficiency (PCE) of 26.1%. Such outstanding performance makes it highly viable for further development. Here, we have meticulously outlined challenges that arose during the industrialization of PSCs and proposed their corresponding solutions based on extensive research. We discussed the main challenges in this field including technological limitations, multi-scenario applications, sustainable development, etc. Mature photovoltaic solutions provide the perovskite community with invaluable insights for overcoming the challenges of industrialization. In the upcoming stages of PSCs advancement, it has become evident that addressing the challenges concerning long-term stability and sustainability is paramount. In this manner, we can facilitate a more effective integration of PSCs into our daily lives.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142123452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-02DOI: 10.1038/s41377-024-01554-7
Chiho Yoon, Eunwoo Park, Sampa Misra, Jin Young Kim, Jin Woo Baik, Kwang Gi Kim, Chan Kwon Jung, Chulhong Kim
In pathological diagnostics, histological images highlight the oncological features of excised specimens, but they require laborious and costly staining procedures. Despite recent innovations in label-free microscopy that simplify complex staining procedures, technical limitations and inadequate histological visualization are still problems in clinical settings. Here, we demonstrate an interconnected deep learning (DL)-based framework for performing automated virtual staining, segmentation, and classification in label-free photoacoustic histology (PAH) of human specimens. The framework comprises three components: (1) an explainable contrastive unpaired translation (E-CUT) method for virtual H&E (VHE) staining, (2) an U-net architecture for feature segmentation, and (3) a DL-based stepwise feature fusion method (StepFF) for classification. The framework demonstrates promising performance at each step of its application to human liver cancers. In virtual staining, the E-CUT preserves the morphological aspects of the cell nucleus and cytoplasm, making VHE images highly similar to real H&E ones. In segmentation, various features (e.g., the cell area, number of cells, and the distance between cell nuclei) have been successfully segmented in VHE images. Finally, by using deep feature vectors from PAH, VHE, and segmented images, StepFF has achieved a 98.00% classification accuracy, compared to the 94.80% accuracy of conventional PAH classification. In particular, StepFF’s classification reached a sensitivity of 100% based on the evaluation of three pathologists, demonstrating its applicability in real clinical settings. This series of DL methods for label-free PAH has great potential as a practical clinical strategy for digital pathology.
{"title":"Deep learning-based virtual staining, segmentation, and classification in label-free photoacoustic histology of human specimens","authors":"Chiho Yoon, Eunwoo Park, Sampa Misra, Jin Young Kim, Jin Woo Baik, Kwang Gi Kim, Chan Kwon Jung, Chulhong Kim","doi":"10.1038/s41377-024-01554-7","DOIUrl":"https://doi.org/10.1038/s41377-024-01554-7","url":null,"abstract":"<p>In pathological diagnostics, histological images highlight the oncological features of excised specimens, but they require laborious and costly staining procedures. Despite recent innovations in label-free microscopy that simplify complex staining procedures, technical limitations and inadequate histological visualization are still problems in clinical settings. Here, we demonstrate an interconnected deep learning (DL)-based framework for performing automated virtual staining, segmentation, and classification in label-free photoacoustic histology (PAH) of human specimens. The framework comprises three components: (1) an explainable contrastive unpaired translation (E-CUT) method for virtual H&E (VHE) staining, (2) an U-net architecture for feature segmentation, and (3) a DL-based stepwise feature fusion method (StepFF) for classification. The framework demonstrates promising performance at each step of its application to human liver cancers. In virtual staining, the E-CUT preserves the morphological aspects of the cell nucleus and cytoplasm, making VHE images highly similar to real H&E ones. In segmentation, various features (e.g., the cell area, number of cells, and the distance between cell nuclei) have been successfully segmented in VHE images. Finally, by using deep feature vectors from PAH, VHE, and segmented images, StepFF has achieved a 98.00% classification accuracy, compared to the 94.80% accuracy of conventional PAH classification. In particular, StepFF’s classification reached a sensitivity of 100% based on the evaluation of three pathologists, demonstrating its applicability in real clinical settings. This series of DL methods for label-free PAH has great potential as a practical clinical strategy for digital pathology.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142118069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-02DOI: 10.1038/s41377-024-01565-4
Muhammad Afnan Ansari, Hammad Ahmed, Yan Li, Guanchao Wang, Jemma E. Callaghan, Ruoxing Wang, James Downing, Xianzhong Chen
Metalenses can integrate the functionalities of multiple optical components thanks to the unprecedented capability of optical metasurfaces in light control. With the rapid development of optical metasurfaces, metalenses continue to evolve. Polarization and color play a very important role in understanding optics and serve as valuable tools for gaining insights into our world. Benefiting from the design flexibility of metasurfaces, we propose and experimentally demonstrate a super metalens that can realize multifaceted control of focal points along any 3D curved trajectory. The wavelengths and polarization states of all focal points are engineered in a desirable manner. The super metalens can simultaneously realize customized 3D positioning, polarization states, and wavelengths of focal points, which are experimentally demonstrated with incident wavelengths ranging from 501 to 700 nm. We further showcase the application of the developed super metalenses in 3D optical distance measurement. The compact nature of metasurfaces and unique properties of the proposed super metalenses hold promise to dramatically miniaturize and simplify the optical architecture for applications in optical metrology, imaging, detection, and security.
{"title":"Multifaceted control of focal points along an arbitrary 3D curved trajectory","authors":"Muhammad Afnan Ansari, Hammad Ahmed, Yan Li, Guanchao Wang, Jemma E. Callaghan, Ruoxing Wang, James Downing, Xianzhong Chen","doi":"10.1038/s41377-024-01565-4","DOIUrl":"https://doi.org/10.1038/s41377-024-01565-4","url":null,"abstract":"<p>Metalenses can integrate the functionalities of multiple optical components thanks to the unprecedented capability of optical metasurfaces in light control. With the rapid development of optical metasurfaces, metalenses continue to evolve. Polarization and color play a very important role in understanding optics and serve as valuable tools for gaining insights into our world. Benefiting from the design flexibility of metasurfaces, we propose and experimentally demonstrate a super metalens that can realize multifaceted control of focal points along any 3D curved trajectory. The wavelengths and polarization states of all focal points are engineered in a desirable manner. The super metalens can simultaneously realize customized 3D positioning, polarization states, and wavelengths of focal points, which are experimentally demonstrated with incident wavelengths ranging from 501 to 700 nm. We further showcase the application of the developed super metalenses in 3D optical distance measurement. The compact nature of metasurfaces and unique properties of the proposed super metalenses hold promise to dramatically miniaturize and simplify the optical architecture for applications in optical metrology, imaging, detection, and security.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142118068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-02DOI: 10.1038/s41377-024-01546-7
Yunxiang Song, Yaowen Hu, Xinrui Zhu, Kiyoul Yang, Marko Lončar
Dissipative Kerr solitons from optical microresonators, commonly referred to as soliton microcombs, have been developed for a broad range of applications, including precision measurement, optical frequency synthesis, and ultra-stable microwave and millimeter wave generation, all on a chip. An important goal for microcombs is self-referencing, which requires octave-spanning bandwidths to detect and stabilize the comb carrier envelope offset frequency. Further, detection and locking of the comb spacings are often achieved using frequency division by electro-optic modulation. The thin-film lithium niobate photonic platform, with its low loss, strong second- and third-order nonlinearities, as well as large Pockels effect, is ideally suited for these tasks. However, octave-spanning soliton microcombs are challenging to demonstrate on this platform, largely complicated by strong Raman effects hindering reliable fabrication of soliton devices. Here, we demonstrate entirely connected and octave-spanning soliton microcombs on thin-film lithium niobate. With appropriate control over microresonator free spectral range and dissipation spectrum, we show that soliton-inhibiting Raman effects are suppressed, and soliton devices are fabricated with near-unity yield. Our work offers an unambiguous method for soliton generation on strongly Raman-active materials. Further, it anticipates monolithically integrated, self-referenced frequency standards in conjunction with established technologies, such as periodically poled waveguides and electro-optic modulators, on thin-film lithium niobate.
{"title":"Octave-spanning Kerr soliton frequency combs in dispersion- and dissipation-engineered lithium niobate microresonators","authors":"Yunxiang Song, Yaowen Hu, Xinrui Zhu, Kiyoul Yang, Marko Lončar","doi":"10.1038/s41377-024-01546-7","DOIUrl":"https://doi.org/10.1038/s41377-024-01546-7","url":null,"abstract":"<p>Dissipative Kerr solitons from optical microresonators, commonly referred to as soliton microcombs, have been developed for a broad range of applications, including precision measurement, optical frequency synthesis, and ultra-stable microwave and millimeter wave generation, all on a chip. An important goal for microcombs is self-referencing, which requires octave-spanning bandwidths to detect and stabilize the comb carrier envelope offset frequency. Further, detection and locking of the comb spacings are often achieved using frequency division by electro-optic modulation. The thin-film lithium niobate photonic platform, with its low loss, strong second- and third-order nonlinearities, as well as large Pockels effect, is ideally suited for these tasks. However, octave-spanning soliton microcombs are challenging to demonstrate on this platform, largely complicated by strong Raman effects hindering reliable fabrication of soliton devices. Here, we demonstrate entirely connected and octave-spanning soliton microcombs on thin-film lithium niobate. With appropriate control over microresonator free spectral range and dissipation spectrum, we show that soliton-inhibiting Raman effects are suppressed, and soliton devices are fabricated with near-unity yield. Our work offers an unambiguous method for soliton generation on strongly Raman-active materials. Further, it anticipates monolithically integrated, self-referenced frequency standards in conjunction with established technologies, such as periodically poled waveguides and electro-optic modulators, on thin-film lithium niobate.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142118067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-30DOI: 10.1038/s41377-024-01541-y
Ruicong Zhang, Zicheng Song, Wenxin Cao, Gang Gao, Lei Yang, Yurong He, Jiecai Han, Zhibo Zhang, Tianyu Wang, Jiaqi Zhu
A novel multispectral smart window has been proposed, which features dynamic modulation of light transmittance and effective shielding against electromagnetic microwave radiation. This design integrates liquid crystal dynamic scattering and dye doping techniques, enabling the dual regulation of transmittance and scattering within a single-layer smart window. Additionally, the precise control of conductive film thickness ensures the attainment of robust microwave signal shielding. We present a theoretical model for ion movement in the presence of an alternating electric field, along with a novel approach to manipulate negative dielectric constant. The proposed model successfully enables a rapid transition between light transparent, absorbing and haze states, with an optimum drive frequency adjustable to approximately 300 Hz. Furthermore, the resistive design of the conductive layer effectively mitigates microwave radiation within the 2−18 GHz range. These findings offer an innovative perspective for future advancements in environmental construction.
{"title":"Multispectral smart window: Dynamic light modulation and electromagnetic microwave shielding","authors":"Ruicong Zhang, Zicheng Song, Wenxin Cao, Gang Gao, Lei Yang, Yurong He, Jiecai Han, Zhibo Zhang, Tianyu Wang, Jiaqi Zhu","doi":"10.1038/s41377-024-01541-y","DOIUrl":"https://doi.org/10.1038/s41377-024-01541-y","url":null,"abstract":"<p>A novel multispectral smart window has been proposed, which features dynamic modulation of light transmittance and effective shielding against electromagnetic microwave radiation. This design integrates liquid crystal dynamic scattering and dye doping techniques, enabling the dual regulation of transmittance and scattering within a single-layer smart window. Additionally, the precise control of conductive film thickness ensures the attainment of robust microwave signal shielding. We present a theoretical model for ion movement in the presence of an alternating electric field, along with a novel approach to manipulate negative dielectric constant. The proposed model successfully enables a rapid transition between light transparent, absorbing and haze states, with an optimum drive frequency adjustable to approximately 300 Hz. Furthermore, the resistive design of the conductive layer effectively mitigates microwave radiation within the 2−18 GHz range. These findings offer an innovative perspective for future advancements in environmental construction.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142100817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-29DOI: 10.1038/s41377-024-01515-0
Haiyan Ou
Silicon carbide (SiC) is emerging as a promising material platform for quantum photonic integrated circuits (QPICs). A quantum light source is one of the fundamental building blocks for QPICs. A high-performance quantum light source from SiC platform will facilitate SiC’s infiltration into QPICs.
{"title":"Silicon carbide, the next-generation integrated platform for quantum technology","authors":"Haiyan Ou","doi":"10.1038/s41377-024-01515-0","DOIUrl":"https://doi.org/10.1038/s41377-024-01515-0","url":null,"abstract":"<p>Silicon carbide (SiC) is emerging as a promising material platform for quantum photonic integrated circuits (QPICs). A quantum light source is one of the fundamental building blocks for QPICs. A high-performance quantum light source from SiC platform will facilitate SiC’s infiltration into QPICs.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142090074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-29DOI: 10.1038/s41377-024-01588-x
Yogeshwar Nath Mishra, Peng Wang, Florian J. Bauer, Murthy S. Gudipati, Lihong V. Wang
The creation of carbonaceous nanoparticles and their dynamics in hydrocarbon flames are still debated in environmental, combustion, and material sciences. In this study, we introduce single-pulse femtosecond laser sheet-compressed ultrafast photography (fsLS-CUP), an ultrafast imaging technique specifically designed to shed light on and capture ultrafast dynamics stemming from interactions between femtosecond lasers and nanoparticles in flames in a single-shot. fsLS-CUP enables the first-time real-time billion frames-per-second (Gfps) simultaneous two-dimensional (2D) imaging of laser-induced fluorescence (LIF) and laser-induced heating (LIH) that are originated from polycyclic aromatic hydrocarbons (PAHs) and soot particles, respectively. Furthermore, fsLS-CUP provides the real-time spatiotemporal map of femtosecond laser-soot interaction as elastic light scattering (ELS) at an astonishing 250 Gfps. In contrast to existing single-shot ultrafast imaging approaches, which are limited to millions of frames per second only and require multiple laser pulses, our method employs only a single pulse and captures the entire dynamics of laser-induced signals at hundreds of Gfps. Using a single pulse does not change the optical properties of nanoparticles for a following pulse, thus allowing reliable spatiotemporal mapping. Moreover, we found that particle inception and growth are derived from precursors. In essence, as an imaging modality, fsLS-CUP offers ultrafast 2D diagnostics, contributing to the fundamental understanding of nanoparticle’s inception and broader applications across different fields, such as material science and biomedical engineering.
{"title":"Single-pulse ultrafast real-time simultaneous planar imaging of femtosecond laser-nanoparticle dynamics in flames","authors":"Yogeshwar Nath Mishra, Peng Wang, Florian J. Bauer, Murthy S. Gudipati, Lihong V. Wang","doi":"10.1038/s41377-024-01588-x","DOIUrl":"https://doi.org/10.1038/s41377-024-01588-x","url":null,"abstract":"<p>The creation of carbonaceous nanoparticles and their dynamics in hydrocarbon flames are still debated in environmental, combustion, and material sciences. In this study, we introduce single-pulse femtosecond laser sheet-compressed ultrafast photography (fsLS-CUP), an ultrafast imaging technique specifically designed to shed light on and capture ultrafast dynamics stemming from interactions between femtosecond lasers and nanoparticles in flames in a single-shot. fsLS-CUP enables the first-time real-time billion frames-per-second (Gfps) simultaneous two-dimensional (2D) imaging of laser-induced fluorescence (LIF) and laser-induced heating (LIH) that are originated from polycyclic aromatic hydrocarbons (PAHs) and soot particles, respectively. Furthermore, fsLS-CUP provides the real-time spatiotemporal map of femtosecond laser-soot interaction as elastic light scattering (ELS) at an astonishing 250 Gfps. In contrast to existing single-shot ultrafast imaging approaches, which are limited to millions of frames per second only and require multiple laser pulses, our method employs only a single pulse and captures the entire dynamics of laser-induced signals at hundreds of Gfps. Using a single pulse does not change the optical properties of nanoparticles for a following pulse, thus allowing reliable spatiotemporal mapping. Moreover, we found that particle inception and growth are derived from precursors. In essence, as an imaging modality, fsLS-CUP offers ultrafast 2D diagnostics, contributing to the fundamental understanding of nanoparticle’s inception and broader applications across different fields, such as material science and biomedical engineering.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142090076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luminescent metal halides are attracting growing attention as scintillators for X-ray imaging in safety inspection, medical diagnosis, etc. Here we present brand-new hybrid Eu(II)-bromide scintillators, 1D type [Et4N]EuBr3·MeOH and 0D type [Me4N]6Eu5Br16·MeOH, with spin-allowed 5d-4f bandgap transition emission toward simplified carrier transport during scintillation process. The 1D/0D structures with edge/face -sharing [EuBr6]4− octahedra further contribute to lowing bandgaps and enhancing quantum confinement effect, enabling efficient scintillation performance (light yield ~73100 ± 800 Ph MeV−1, detect limit ~18.6 nGy s−1, X-ray afterglow ~ 1% @ 9.6 μs). We demonstrate the X-ray imaging with 27.3 lp mm−1 resolution by embedding Eu(II)-based scintillators into AAO film. Our results create the new family of low-dimensional rare-earth-based halides for scintillation and related optoelectronic applications.
{"title":"Hybrid Eu(II)-bromide scintillators with efficient 5d-4f bandgap transition for X-ray imaging","authors":"Kai Han, Jiance Jin, Yuzhen Wang, Xinquan Zhou, Yongsheng Sun, Lihan Chen, Zhiguo Xia","doi":"10.1038/s41377-024-01589-w","DOIUrl":"https://doi.org/10.1038/s41377-024-01589-w","url":null,"abstract":"<p>Luminescent metal halides are attracting growing attention as scintillators for X-ray imaging in safety inspection, medical diagnosis, etc. Here we present brand-new hybrid Eu(II)-bromide scintillators, 1D type [Et<sub>4</sub>N]EuBr<sub>3</sub>·MeOH and 0D type [Me<sub>4</sub>N]<sub>6</sub>Eu<sub>5</sub>Br<sub>16</sub>·MeOH, with spin-allowed 5<i>d</i>-4<i>f</i> bandgap transition emission toward simplified carrier transport during scintillation process. The 1D/0D structures with edge/face -sharing [EuBr<sub>6</sub>]<sup>4−</sup> octahedra further contribute to lowing bandgaps and enhancing quantum confinement effect, enabling efficient scintillation performance (light yield ~73100 ± 800 Ph MeV<sup>−1</sup>, detect limit ~18.6 nGy s<sup>−1</sup>, X-ray afterglow ~ 1% @ 9.6 μs). We demonstrate the X-ray imaging with 27.3 lp mm<sup>−1</sup> resolution by embedding Eu(II)-based scintillators into AAO film. Our results create the new family of low-dimensional rare-earth-based halides for scintillation and related optoelectronic applications.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142090075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-28DOI: 10.1038/s41377-024-01566-3
Jose Ilton De Oliveira Filho, Abderrahmen Trichili, Omar Alkhazragi, Mohamed-Slim Alouini, Boon S. Ooi, Khaled Nabil Salama
Simultaneous lightwave information and power transfer (SLIPT), co-existing with optical wireless communication, holds an enormous potential to provide continuous charging to remote Internet of Things (IoT) devices while ensuring connectivity. Combining SLIPT with an omnidirectional receiver, we can leverage a higher power budget while maintaining a stable connection, a major challenge for optical wireless communication systems. Here, we design a multiplexed SLIPT-based system comprising an array of photodetectors (PDs) arranged in a 3 × 3 configuration. The system enables decoding information from multiple light beams while simultaneously harvesting energy. The PDs can swiftly switch between photoconductive and photovoltaic modes to maximize information transfer rates and provide on-demand energy harvesting. Additionally, we investigated the ability to decode information and harvest energy with a particular quadrant set of PDs from the array, allowing beam tracking and spatial diversity. The design was explored in a smaller version for higher data rates and a bigger one for higher power harvesting. We report a self-powering device that can achieve a gross data rate of 25.7 Mbps from a single-input single-output (SISO) and an 85.2 Mbps net data rate in a multiple-input multiple-output (MIMO) configuration. Under a standard AMT1.5 illumination, the device can harvest up to 87.33 mW, around twice the power needed to maintain the entire system. Our work paves the way for deploying autonomous IoT devices in harsh environments and their potential use in space applications.
{"title":"Reconfigurable MIMO-based self-powered battery-less light communication system","authors":"Jose Ilton De Oliveira Filho, Abderrahmen Trichili, Omar Alkhazragi, Mohamed-Slim Alouini, Boon S. Ooi, Khaled Nabil Salama","doi":"10.1038/s41377-024-01566-3","DOIUrl":"https://doi.org/10.1038/s41377-024-01566-3","url":null,"abstract":"<p>Simultaneous lightwave information and power transfer (SLIPT), co-existing with optical wireless communication, holds an enormous potential to provide continuous charging to remote Internet of Things (IoT) devices while ensuring connectivity. Combining SLIPT with an omnidirectional receiver, we can leverage a higher power budget while maintaining a stable connection, a major challenge for optical wireless communication systems. Here, we design a multiplexed SLIPT-based system comprising an array of photodetectors (PDs) arranged in a 3 × 3 configuration. The system enables decoding information from multiple light beams while simultaneously harvesting energy. The PDs can swiftly switch between photoconductive and photovoltaic modes to maximize information transfer rates and provide on-demand energy harvesting. Additionally, we investigated the ability to decode information and harvest energy with a particular quadrant set of PDs from the array, allowing beam tracking and spatial diversity. The design was explored in a smaller version for higher data rates and a bigger one for higher power harvesting. We report a self-powering device that can achieve a gross data rate of 25.7 Mbps from a single-input single-output (SISO) and an 85.2 Mbps net data rate in a multiple-input multiple-output (MIMO) configuration. Under a standard AMT1.5 illumination, the device can harvest up to 87.33 mW, around twice the power needed to maintain the entire system. Our work paves the way for deploying autonomous IoT devices in harsh environments and their potential use in space applications.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142084823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}