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Author Correction: Planarized THz quantum cascade lasers for broadband coherent photonics. 作者更正:用于宽带相干光子学的平面化太赫兹量子级联激光器。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-07-04 DOI: 10.1038/s41377-024-01467-5
Urban Senica, Andres Forrer, Tudor Olariu, Paolo Micheletti, Sara Cibella, Guido Torrioli, Mattias Beck, Jérôme Faist, Giacomo Scalari
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引用次数: 0
Time-of-flight resolved stimulated Raman scattering microscopy using counter-propagating ultraslow Bessel light bullets generation. 利用反向传播超低贝塞尔光子弹生成的飞行时间分辨受激拉曼散射显微镜。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-07-01 DOI: 10.1038/s41377-024-01498-y
Shulang Lin, Li Gong, Zhiwei Huang

We present a novel time-of-flight resolved Bessel light bullet-enabled stimulated Raman scattering (B2-SRS) microscopy for deeper tissue 3D chemical imaging with high resolution without a need for mechanical z-scanning. To accomplish the tasks, we conceive a unique method to enable optical sectioning by generating the counter-propagating pump and Stokes Bessel light bullets in the sample, in which the group velocities of the Bessel light bullets are made ultraslow (e.g., vg ≈ 0.1c) and tunable by introducing programmable angular dispersions with a spatial light modulator. We theoretically analyze the working principle of the collinear multicolor Bessel light bullet generations and velocity controls with the relative time-of-flight resolved detection for SRS 3D deep tissue imaging. We have also built the B2-SRS imaging system and present the first demonstration of B2-SRS microscopy with Bessel light bullets for 3D chemical imaging in a variety of samples (e.g., polymer bead phantoms, biological samples such as spring onion tissue and porcine brain) with high resolution. The B2-SRS technique provides a > 2-fold improvement in imaging depth in porcine brain tissue compared to conventional SRS microscopy. The method of optical sectioning in tissue using counter-propagating ultraslow Bessel light bullets developed in B2-SRS is generic and easy to perform and can be readily extended to other nonlinear optical imaging modalities to advance 3D microscopic imaging in biological and biomedical systems and beyond.

我们提出了一种新颖的飞行时间分辨贝塞尔光子弹受激拉曼散射(B2-SRS)显微镜,可用于深层组织的高分辨率三维化学成像,而无需机械Z扫描。为了完成这些任务,我们构思了一种独特的方法,通过在样品中产生反向传播的泵浦和斯托克斯贝塞尔光弹来实现光学切片,其中贝塞尔光弹的群速度是超低的(例如,vg ≈ 0.1c),并可通过空间光调制器引入可编程角色散来进行调谐。我们从理论上分析了用于 SRS 3D 深部组织成像的准线多色贝塞尔光子弹代和速度控制与相对飞行时间分辨检测的工作原理。我们还建立了 B2-SRS 成像系统,并首次展示了 B2-SRS 显微镜与贝塞尔光弹在多种样品(如聚合物珠模型、生物样品如春葱组织和猪脑)中的高分辨率三维化学成像。与传统的 SRS 显微技术相比,B2-SRS 技术在猪脑组织中的成像深度提高了 2 倍以上。B2-SRS 中开发的使用反向传播超低贝塞尔光子弹在组织中进行光学切片的方法具有通用性,易于执行,可随时扩展到其他非线性光学成像模式,以推进生物和生物医学系统及其他系统的三维显微成像。
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引用次数: 0
Anisotropy-free arrayed waveguide gratings on X-cut thin film lithium niobate platform of in-plane anisotropy. 面内各向异性的 X 切面铌酸锂薄膜平台上的无各向异性阵列波导光栅。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-29 DOI: 10.1038/s41377-024-01506-1
Junjie Yi, Changjian Guo, Ziliang Ruan, Gengxin Chen, Haiqiang Wei, Liwang Lu, Shengqi Gong, Xiaofu Pan, Xiaowan Shen, Xiaowei Guan, Daoxin Dai, Kangping Zhong, Liu Liu

Arrayed waveguide grating is a versatile and scalable integrated light dispersion device, which has been widely adopted in various applications, including, optical communications and optical sensing. Recently, thin-film lithium niobate emerges as a promising photonic integration platform, due to its ability of shrinking largely the size of typical lithium niobate based optical devices. This would also enable multifunctional photonic integrated chips on a single lithium niobate substrate. However, due to the intrinsic anisotropy of the material, to build an arrayed waveguide grating on X-cut thin-film lithium niobate has never been successful. Here, a universal strategy to design anisotropy-free dispersive components on a uniaxial in-plane anisotropic photonic integration platform is introduced for the first time. This leads to the first implementation of arrayed waveguide gratings on X-cut thin-film lithium niobate with various configurations and high-performances. The best insertion loss of 2.4 dB and crosstalk of -24.1 dB is obtained for the fabricated arrayed waveguide grating devices. Applications of such arrayed waveguide gratings as a wavelength router and in a wavelength-division multiplexed optical transmission system are also demonstrated.

阵列波导光栅是一种多功能、可扩展的集成光色散器件,已被广泛应用于光通信和光传感等多个领域。近来,铌酸锂薄膜成为一种前景广阔的光子集成平台,因为它能在很大程度上缩小基于铌酸锂的典型光学器件的尺寸。这也将在单一铌酸锂基底上实现多功能光子集成芯片。然而,由于铌酸锂材料的固有各向异性,在 X 切面薄膜铌酸锂上构建阵列波导光栅的工作从未取得成功。在这里,我们首次提出了在单轴平面内各向异性光子集成平台上设计无各向异性色散元件的通用策略。由此,在 X 切面铌酸锂薄膜上首次实现了具有各种配置和高性能的阵列波导光栅。所制造的阵列波导光栅器件的最佳插入损耗为 2.4 dB,串扰为 -24.1 dB。此外,还展示了这种阵列波导光栅在波长路由器和波分复用光传输系统中的应用。
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引用次数: 0
Emerging probing perspective of two-dimensional materials physics: terahertz emission spectroscopy. 二维材料物理学的新兴探测视角:太赫兹发射光谱学。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-29 DOI: 10.1038/s41377-024-01486-2
Yifei Wu, Yuqi Wang, Di Bao, Xiaonan Deng, Simian Zhang, Lin Yu-Chun, Shengxian Ke, Jianing Liu, Yingjie Liu, Zeli Wang, Pingren Ham, Andrew Hanna, Jiaming Pan, Xinyue Hu, Zhengcao Li, Ji Zhou, Chen Wang

Terahertz (THz) emission spectroscopy (TES) has emerged as a highly effective and versatile technique for investigating the photoelectric properties of diverse materials and nonlinear physical processes in the past few decades. Concurrently, research on two-dimensional (2D) materials has experienced substantial growth due to their atomically thin structures, exceptional mechanical and optoelectronic properties, and the potential for applications in flexible electronics, sensing, and nanoelectronics. Specifically, these materials offer advantages such as tunable bandgap, high carrier mobility, wideband optical absorption, and relatively short carrier lifetime. By applying TES to investigate the 2D materials, their interfaces and heterostructures, rich information about the interplay among photons, charges, phonons and spins can be unfolded, which provides fundamental understanding for future applications. Thus it is timely to review the nonlinear processes underlying THz emission in 2D materials including optical rectification, photon-drag, high-order harmonic generation and spin-to-charge conversion, showcasing the rich diversity of the TES employed to unravel the complex nature of these materials. Typical applications based on THz emissions, such as THz lasers, ultrafast imaging and biosensors, are also discussed. Step further, we analyzed the unique advantages of spintronic terahertz emitters and the future technological advancements in the development of new THz generation mechanisms leading to advanced THz sources characterized by wide bandwidth, high power and integration, suitable for industrial and commercial applications. The continuous advancement and integration of TES with the study of 2D materials and heterostructures promise to revolutionize research in different areas, including basic materials physics, novel optoelectronic devices, and chips for post-Moore's era.

太赫兹(THz)发射光谱(TES)在过去几十年中已成为研究各种材料的光电特性和非线性物理过程的一种高效、多用途技术。与此同时,由于二维(2D)材料具有原子级薄结构、优异的机械和光电特性,以及在柔性电子学、传感和纳米电子学中的应用潜力,对二维材料的研究也经历了大幅增长。具体来说,这些材料具有可调带隙、高载流子迁移率、宽带光吸收和相对较短的载流子寿命等优点。通过应用 TES 研究二维材料及其界面和异质结构,可以揭示光子、电荷、声子和自旋之间相互作用的丰富信息,从而为未来应用提供基础性的理解。因此,现在正是回顾二维材料中太赫兹发射的非线性过程(包括光学整流、光子拖曳、高阶谐波产生和自旋到电荷的转换)的好时机。我们还讨论了基于太赫兹发射的典型应用,如太赫兹激光、超快成像和生物传感器。此外,我们还分析了自旋电子太赫兹发射器的独特优势,以及未来在开发新的太赫兹产生机制方面的技术进步,这些机制将产生具有宽带宽、高功率和高集成度等特点的先进太赫兹源,适用于工业和商业应用。太赫兹辐射的不断进步以及与二维材料和异质结构研究的结合,有望彻底改变不同领域的研究,包括基础材料物理、新型光电器件和后摩尔时代的芯片。
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引用次数: 0
Chiral quantum heating and cooling with an optically controlled ion. 利用光学控制离子进行手性量子加热和冷却。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-26 DOI: 10.1038/s41377-024-01483-5
Jin-Tao Bu, Jian-Qi Zhang, Ge-Yi Ding, Jia-Chong Li, Jia-Wei Zhang, Bin Wang, Wen-Qiang Ding, Wen-Fei Yuan, Liang Chen, Qi Zhong, Ali Keçebaş, Şahin K Özdemir, Fei Zhou, Hui Jing, Mang Feng

Quantum heat engines and refrigerators are open quantum systems, whose dynamics can be well understood using a non-Hermitian formalism. A prominent feature of non-Hermiticity is the existence of exceptional points (EPs), which has no counterpart in closed quantum systems. It has been shown in classical systems that dynamical encirclement in the vicinity of an EP, whether the loop includes the EP or not, could lead to chiral mode conversion. Here, we show that this is valid also for quantum systems when dynamical encircling is performed in the vicinity of their Liouvillian EPs (LEPs), which include the effects of quantum jumps and associated noise-an important quantum feature not present in previous works. We demonstrate, using a Paul-trapped ultracold ion, the first chiral quantum heating and refrigeration by dynamically encircling a closed loop in the vicinity of an LEP. We witness the cycling direction to be associated with the chirality and heat release (absorption) of the quantum heat engine (quantum refrigerator). Our experiments have revealed that not only the adiabaticity breakdown but also the Landau-Zener-Stückelberg process play an essential role during dynamic encircling, resulting in chiral thermodynamic cycles. Our observations contribute to further understanding of chiral and topological features in non-Hermitian systems and pave a way to exploring the relation between chirality and quantum thermodynamics.

量子热机和冰箱是开放的量子系统,其动力学可以用非赫米特形式主义很好地理解。非ermiticity 的一个显著特点是例外点(EP)的存在,这在封闭量子系统中并不存在。在经典系统中已经证明,无论环路是否包括 EP,EP 附近的动态包围都可能导致手性模式转换。在这里,我们证明了当动态环绕在量子系统的Liouvillian EPs(LEPs)附近进行时,这也适用于量子系统,LEPs包括量子跃迁和相关噪声的影响--这是以前的研究中没有的重要量子特征。我们利用保罗俘获的超冷离子,通过在 LEP 附近动态环绕闭环,首次演示了手性量子加热和制冷。我们见证了循环方向与量子热引擎(量子冰箱)的手性和热量释放(吸收)相关。我们的实验发现,在动态环绕过程中,不仅绝热性击穿,而且朗道-齐纳-斯图克尔伯格过程也起着至关重要的作用,从而导致手性热力学循环。我们的观察有助于进一步理解非赫米提系统中的手性和拓扑特征,并为探索手性与量子热力学之间的关系铺平了道路。
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引用次数: 0
EventLFM: event camera integrated Fourier light field microscopy for ultrafast 3D imaging. EventLFM:用于超快三维成像的事件相机集成傅立叶光场显微镜。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-26 DOI: 10.1038/s41377-024-01502-5
Ruipeng Guo, Qianwan Yang, Andrew S Chang, Guorong Hu, Joseph Greene, Christopher V Gabel, Sixian You, Lei Tian

Ultrafast 3D imaging is indispensable for visualizing complex and dynamic biological processes. Conventional scanning-based techniques necessitate an inherent trade-off between acquisition speed and space-bandwidth product (SBP). Emerging single-shot 3D wide-field techniques offer a promising alternative but are bottlenecked by the synchronous readout constraints of conventional CMOS systems, thus restricting data throughput to maintain high SBP at limited frame rates. To address this, we introduce EventLFM, a straightforward and cost-effective system that overcomes these challenges by integrating an event camera with Fourier light field microscopy (LFM), a state-of-the-art single-shot 3D wide-field imaging technique. The event camera operates on a novel asynchronous readout architecture, thereby bypassing the frame rate limitations inherent to conventional CMOS systems. We further develop a simple and robust event-driven LFM reconstruction algorithm that can reliably reconstruct 3D dynamics from the unique spatiotemporal measurements captured by EventLFM. Experimental results demonstrate that EventLFM can robustly reconstruct fast-moving and rapidly blinking 3D fluorescent samples at kHz frame rates. Furthermore, we highlight EventLFM's capability for imaging of blinking neuronal signals in scattering mouse brain tissues and 3D tracking of GFP-labeled neurons in freely moving C. elegans. We believe that the combined ultrafast speed and large 3D SBP offered by EventLFM may open up new possibilities across many biomedical applications.

超快三维成像对于观察复杂而动态的生物过程是必不可少的。传统的扫描技术必须在采集速度和空间带宽乘积(SBP)之间做出权衡。新兴的单镜头三维宽视场技术提供了一种有前途的替代方案,但却受到传统 CMOS 系统同步读出限制的瓶颈,从而限制了数据吞吐量,无法在有限的帧速率下保持较高的 SBP。为了解决这个问题,我们推出了 EventLFM,这是一种简单、经济高效的系统,通过将事件相机与傅立叶光场显微镜(LFM)(一种最先进的单镜头三维宽视场成像技术)集成,克服了这些挑战。事件相机采用新颖的异步读出架构,从而绕过了传统 CMOS 系统固有的帧速率限制。我们进一步开发了一种简单、稳健的事件驱动 LFM 重建算法,该算法可以从 EventLFM 捕捉到的独特时空测量数据中可靠地重建三维动态。实验结果表明,EventLFM 能够以 kHz 帧频稳健地重建快速移动和快速闪烁的三维荧光样本。此外,我们还重点介绍了 EventLFM 对散射小鼠脑组织中闪烁神经元信号的成像能力,以及对自由移动的秀丽隐杆线虫中 GFP 标记神经元的三维跟踪能力。我们相信,EventLFM 所提供的超快速度和大三维 SBP 的组合可能会为许多生物医学应用带来新的可能性。
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引用次数: 0
Color coded metadevices toward programmed terahertz switching. 实现编程太赫兹开关的彩色编码元器件。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-25 DOI: 10.1038/s41377-024-01495-1
Weibao He, Xiang'ai Cheng, Siyang Hu, Ziheng Ren, Zhongyi Yu, Shun Wan, Yuze Hu, Tian Jiang

Terahertz modulators play a critical role in high-speed wireless communication, non-destructive imaging, and so on, which have attracted a large amount of research interest. Nevertheless, all-optical terahertz modulation, an ultrafast dynamical control approach, remains to be limited in terms of encoding and multifunction. Here we experimentally demonstrated an optical-programmed terahertz switching realized by combining optical metasurfaces with the terahertz metasurface, resulting in 2-bit dual-channel terahertz encoding. The terahertz metasurface, made up of semiconductor islands and artificial microstructures, enables effective all-optical programming by providing multiple frequency channels with ultrafast modulation at the nanosecond level. Meanwhile, optical metasurfaces covered in terahertz metasurface alter the spatial light field distribution to obtain color code. According to the time-domain coupled mode theory analysis, the energy dissipation modes in terahertz metasurface can be independently controlled by color excitation, which explains the principle of 2-bit encoding well. This work establishes a platform for all-optical programmed terahertz metadevices and may further advance the application of composite metasurface in terahertz manipulation.

太赫兹调制器在高速无线通信、无损成像等领域发挥着至关重要的作用,吸引了大量研究人员的关注。然而,作为一种超快动态控制方法,全光太赫兹调制在编码和多功能性方面仍然受到限制。在这里,我们通过实验演示了一种光编程太赫兹开关,它是通过将光学元表面与太赫兹元表面相结合来实现的,从而实现了 2 位双通道太赫兹编码。太赫兹元表面由半导体岛和人工微结构组成,通过提供纳秒级超快调制的多个频率通道,实现了有效的全光编程。同时,太赫兹元表面覆盖的光学元表面可改变空间光场分布,从而获得色码。根据时域耦合模式理论分析,太赫兹元表面中的能量耗散模式可由颜色激励独立控制,很好地解释了 2 位编码的原理。这项工作为全光编程太赫兹元器件建立了一个平台,可进一步推动复合元表面在太赫兹操纵中的应用。
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引用次数: 0
Light People: Professor Che Ting Chan, curiosity drives to create the impossibilities. 光的人陈哲庭教授,好奇心驱使他创造不可能。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-21 DOI: 10.1038/s41377-024-01497-z
Tingting Sun, Ying Xiong

EDITORIAL: "When something is said to be impossible, there are two points for researchers to initially clarify: whether it really is forbidden by the laws of nature; or whether it is simply that no material that currently exists in nature can do that." Metamaterials are such magical beings, which have physical properties like invisibility, negative refraction, super-resolution, and perfect absorption that are absent from natural materials. It has been rated by Science as one of the top ten scientific and technological breakthroughs affecting human beings in the 21st century.In this issue of Light People, we spoke with a "magic" creator, Professor Che Ting Chan, the Associate Vice-President (Research & Development) of the Hong Kong University of Science and Technology (HKUST), Member of the Hong Kong Academy of Sciences and Fellow of the American Physical Society. He has researched a number of theoretical problems in material physics, investigated the theory behind what they seek to achieve, and modulated light (electromagnetism) and acoustic waves through metamaterials. In the following, let's take a closer look at Professor Che Ting Chan's research life, and appreciate his style and the background of his accomplishment.

编者按:"当一件事情被说成是不可能的时候,研究人员首先要弄清楚两点:它是否真的被自然规律所禁止;或者仅仅是目前自然界中存在的任何材料都无法做到这一点。"超材料就是这样神奇的存在,它具有天然材料所不具备的隐形、负折射、超分辨率、完美吸收等物理特性。本期《光人》,我们采访了一位 "神奇 "的创造者--香港科技大学协理副校长(研究与发展)、香港科学院院士、美国物理学会院士陈哲庭教授。他研究了材料物理学的许多理论问题,探究了这些问题背后的理论,并通过超材料对光(电磁)和声波进行了调制。下面,让我们走近陈哲庭教授的研究生活,领略他的风采和成就背景。
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引用次数: 0
Silicon-photonics-enabled chip-based 3D printer. 基于芯片的硅光子三维打印机。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-06 DOI: 10.1038/s41377-024-01478-2
Sabrina Corsetti, Milica Notaros, Tal Sneh, Alex Stafford, Zachariah A Page, Jelena Notaros

Imagine if it were possible to create 3D objects in the palm of your hand within seconds using only a single photonic chip. Although 3D printing has revolutionized the way we create in nearly every aspect of modern society, current 3D printers rely on large and complex mechanical systems to enable layer-by-layer addition of material. This limits print speed, resolution, portability, form factor, and material complexity. Although there have been recent efforts in developing novel photocuring-based 3D printers that utilize light to transform matter from liquid resins to solid objects using advanced methods, they remain reliant on bulky and complex mechanical systems. To address these limitations, we combine the fields of silicon photonics and photochemistry to propose the first chip-based 3D printer. The proposed system consists of only a single millimeter-scale photonic chip without any moving parts that emits reconfigurable visible-light holograms up into a simple stationary resin well to enable non-mechanical 3D printing. Furthermore, we experimentally demonstrate a stereolithography-inspired proof-of-concept version of the chip-based 3D printer using a visible-light beam-steering integrated optical phased array and visible-light-curable resin, showing 3D printing using a chip-based system for the first time. This work demonstrates the first steps towards a highly-compact, portable, and low-cost solution for the next generation of 3D printers.

试想一下,如果只用一块光子芯片,就能在几秒钟内在手掌中制作出三维物体。尽管三维打印技术已经彻底改变了我们在现代社会几乎方方面面的创造方式,但目前的三维打印机依赖于庞大而复杂的机械系统来逐层添加材料。这限制了打印速度、分辨率、便携性、外形尺寸和材料的复杂性。虽然最近人们一直在努力开发基于光固化技术的新型三维打印机,利用先进的方法将物质从液态树脂转化为固态物体,但它们仍然依赖于庞大而复杂的机械系统。为了解决这些局限性,我们将硅光子学和光化学领域结合起来,提出了第一款基于芯片的三维打印机。所提出的系统仅由一个毫米级光子芯片组成,没有任何移动部件,可将可重新配置的可见光全息图发射到一个简单的固定树脂井中,从而实现非机械式三维打印。此外,我们还通过实验演示了基于芯片的立体光刻三维打印机的概念验证版本,该版本使用了可见光光束转向集成光学相控阵和可见光固化树脂,首次展示了使用基于芯片的系统进行三维打印。这项工作为下一代三维打印机的高紧凑、便携和低成本解决方案迈出了第一步。
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引用次数: 0
Deformable microlaser force sensing. 可变形微激光力传感。
IF 19.4 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-05 DOI: 10.1038/s41377-024-01471-9
Eleni Dalaka, Joseph S Hill, Jonathan H H Booth, Anna Popczyk, Stefan R Pulver, Malte C Gather, Marcel Schubert

Mechanical forces are key regulators of cellular behavior and function, affecting many fundamental biological processes such as cell migration, embryogenesis, immunological responses, and pathological states. Specialized force sensors and imaging techniques have been developed to quantify these otherwise invisible forces in single cells and in vivo. However, current techniques rely heavily on high-resolution microscopy and do not allow interrogation of optically dense tissue, reducing their application to 2D cell cultures and highly transparent biological tissue. Here, we introduce DEFORM, deformable microlaser force sensing, a spectroscopic technique that detects sub-nanonewton forces with unprecedented spatio-temporal resolution. DEFORM is based on the spectral analysis of laser emission from dye-doped oil microdroplets and uses the force-induced lifting of laser mode degeneracy in these droplets to detect nanometer deformations. Following validation by atomic force microscopy and development of a model that links changes in laser spectrum to applied force, DEFORM is used to measure forces in 3D and at depths of hundreds of microns within tumor spheroids and late-stage Drosophila larva. We furthermore show continuous force sensing with single-cell spatial and millisecond temporal resolution, thus paving the way for non-invasive studies of biomechanical forces in advanced stages of embryogenesis, tissue remodeling, and tumor invasion.

机械力是细胞行为和功能的关键调节器,影响着许多基本的生物过程,如细胞迁移、胚胎发育、免疫反应和病理状态。目前已开发出专门的力传感器和成像技术,用于量化单细胞和体内这些原本不可见的力。然而,目前的技术严重依赖于高分辨率显微镜,无法对光学致密组织进行检测,从而降低了它们在二维细胞培养和高透明度生物组织中的应用。在这里,我们介绍了 DEFORM(可变形微激光力传感),这是一种能以前所未有的时空分辨率检测亚纳牛顿力的光谱技术。DEFORM 基于对掺杂染料的油微滴激光发射的光谱分析,并利用这些微滴中激光模式变性的力诱导提升来检测纳米级变形。经过原子力显微镜的验证,并建立了一个将激光光谱变化与作用力联系起来的模型后,DEFORM 被用于测量肿瘤球体和晚期果蝇幼虫内部数百微米深度的三维力。此外,我们还展示了具有单细胞空间分辨率和毫秒时间分辨率的连续力传感,从而为在胚胎发育、组织重塑和肿瘤侵袭的晚期阶段对生物力学力进行非侵入式研究铺平了道路。
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引用次数: 0
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