Pub Date : 2024-08-27DOI: 10.1038/s41377-024-01583-2
Tingting Sun
Editorial: Professor Juejun Hu was admitted by Tsinghua University as top scorer in the science college entrance examination of Fujian Province. After graduating, he went to MIT to pursue further studies, where he continued to excel and became a faculty member. Each step of his journey has been marked by extraordinary achievements, setting a standard that few can match. Today, Prof. Hu is recognized as a leading expert in integrated photonics and optical materials. His pioneering research has not only advanced the frontiers of academia but also made significant impacts on industrial applications. In this interview, we invite you to delve into Prof. Hu's research world, exploring his unique insights into technological innovation and how he uses the power of science to shape the future.
{"title":"Light People: Prof. Juejun Hu, exploring the light.","authors":"Tingting Sun","doi":"10.1038/s41377-024-01583-2","DOIUrl":"10.1038/s41377-024-01583-2","url":null,"abstract":"<p><strong>Editorial: </strong>Professor Juejun Hu was admitted by Tsinghua University as top scorer in the science college entrance examination of Fujian Province. After graduating, he went to MIT to pursue further studies, where he continued to excel and became a faculty member. Each step of his journey has been marked by extraordinary achievements, setting a standard that few can match. Today, Prof. Hu is recognized as a leading expert in integrated photonics and optical materials. His pioneering research has not only advanced the frontiers of academia but also made significant impacts on industrial applications. In this interview, we invite you to delve into Prof. Hu's research world, exploring his unique insights into technological innovation and how he uses the power of science to shape the future.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11350161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142080795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-26DOI: 10.1038/s41377-024-01562-7
Igor Meglinski, Ivan Lopushenko, Anton Sdobnov, Alexander Bykov
Recent advancements in wavefront shaping techniques have facilitated the study of complex structured light's propagation with orbital angular momentum (OAM) within various media. The introduction of spiral phase modulation to the Laguerre-Gaussian (LG) beam during its paraxial propagation is facilitated by the negative gradient of the medium's refractive index change over time, leading to a notable increase in the rate of phase twist, effectively observed as phase retardation of the OAM. This approach attains remarkable sensitivity to even the slightest variations in the medium's refractive index (∼10-6). The phase memory of OAM is revealed as the ability of twisted light to preserve the initial helical phase even propagating through the turbid tissue-like multiple scattering medium. The results confirm fascinating opportunities for exploiting OAM light in biomedical applications, e.g. such as non-invasive trans-cutaneous glucose diagnosis and optical communication through biological tissues and other optically dense media.
{"title":"Phase preservation of orbital angular momentum of light in multiple scattering environment.","authors":"Igor Meglinski, Ivan Lopushenko, Anton Sdobnov, Alexander Bykov","doi":"10.1038/s41377-024-01562-7","DOIUrl":"10.1038/s41377-024-01562-7","url":null,"abstract":"<p><p>Recent advancements in wavefront shaping techniques have facilitated the study of complex structured light's propagation with orbital angular momentum (OAM) within various media. The introduction of spiral phase modulation to the Laguerre-Gaussian (LG) beam during its paraxial propagation is facilitated by the negative gradient of the medium's refractive index change over time, leading to a notable increase in the rate of phase twist, effectively observed as phase retardation of the OAM. This approach attains remarkable sensitivity to even the slightest variations in the medium's refractive index (∼10<sup>-6</sup>). The phase memory of OAM is revealed as the ability of twisted light to preserve the initial helical phase even propagating through the turbid tissue-like multiple scattering medium. The results confirm fascinating opportunities for exploiting OAM light in biomedical applications, e.g. such as non-invasive trans-cutaneous glucose diagnosis and optical communication through biological tissues and other optically dense media.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142073216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-26DOI: 10.1038/s41377-024-01581-4
Chuangchuang Chen, Honggang Gu, Shiyuan Liu
Strict requirement of a coherent spectrum in coherent diffractive imaging (CDI) architectures poses a significant obstacle to achieving efficient photon utilization across the full spectrum. To date, nearly all broadband computational imaging experiments have relied on accurate spectroscopic measurements, as broad spectra are incompatible with conventional CDI systems. This paper presents an advanced approach to broaden the scope of CDI to ultra-broadband illumination with unknown probe spectrum, effectively addresses the key challenges encountered by existing state-of-the-art broadband diffractive imaging frameworks. This advancement eliminates the necessity for prior knowledge of probe spectrum and relaxes constraints on non-dispersive samples, resulting in a significant extension in spectral bandwidth, achieving a nearly fourfold improvement in bandlimit compared to the existing benchmark. Our method not only monochromatizes a broadband diffraction pattern from unknown illumination spectrum, but also determines the compressive sampled profile of spectrum of the diffracted radiation. This superiority is experimentally validated using both CDI and ptychography techniques on an ultra-broadband supercontinuum with relative bandwidth exceeding 40%, revealing a significantly enhanced coherence and improved reconstruction with high fidelity under ultra-broadband illumination.
{"title":"Ultra-broadband diffractive imaging with unknown probe spectrum.","authors":"Chuangchuang Chen, Honggang Gu, Shiyuan Liu","doi":"10.1038/s41377-024-01581-4","DOIUrl":"10.1038/s41377-024-01581-4","url":null,"abstract":"<p><p>Strict requirement of a coherent spectrum in coherent diffractive imaging (CDI) architectures poses a significant obstacle to achieving efficient photon utilization across the full spectrum. To date, nearly all broadband computational imaging experiments have relied on accurate spectroscopic measurements, as broad spectra are incompatible with conventional CDI systems. This paper presents an advanced approach to broaden the scope of CDI to ultra-broadband illumination with unknown probe spectrum, effectively addresses the key challenges encountered by existing state-of-the-art broadband diffractive imaging frameworks. This advancement eliminates the necessity for prior knowledge of probe spectrum and relaxes constraints on non-dispersive samples, resulting in a significant extension in spectral bandwidth, achieving a nearly fourfold improvement in bandlimit compared to the existing benchmark. Our method not only monochromatizes a broadband diffraction pattern from unknown illumination spectrum, but also determines the compressive sampled profile of spectrum of the diffracted radiation. This superiority is experimentally validated using both CDI and ptychography techniques on an ultra-broadband supercontinuum with relative bandwidth exceeding 40%, revealing a significantly enhanced coherence and improved reconstruction with high fidelity under ultra-broadband illumination.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142073217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41377-024-01532-z
Qian Wang, Chenger Wang, Hongliang Shi, Jie Chen, Junye Yang, Alena Beitlerova, Romana Kucerkova, Zhengyang Zhou, Yunyun Li, Martin Nikl, Xilei Sun, Xiaoping OuYang, Yuntao Wu
Materials for radiation detection are critically important and urgently demanded in diverse fields, starting from fundamental scientific research to medical diagnostics, homeland security, and environmental monitoring. Low-dimensional halides (LDHs) exhibiting efficient self-trapped exciton (STE) emission with high photoluminescence quantum yield (PLQY) have recently shown a great potential as scintillators. However, an overlooked issue of exciton-exciton interaction in LDHs under ionizing radiation hinders the broadening of its radiation detection applications. Here, we demonstrate an exceptional enhancement of exciton-harvesting efficiency in zero-dimensional (0D) Cs3Cu2I5:Tl halide single crystals by forming strongly localized Tl-bound excitons. Because of the suppression of non-radiative exciton-exciton interaction, an excellent α/β pulse-shape-discrimination (PSD) figure-of-merit (FoM) factor of 2.64, a superior rejection ratio of 10-9, and a high scintillation yield of 26 000 photons MeV-1 under 5.49 MeV α-ray are achieved in Cs3Cu2I5:Tl single crystals, outperforming the commercial ZnS:Ag/PVT composites for charged particle detection applications. Furthermore, a radiation detector prototype based on Cs3Cu2I5:Tl single crystal demonstrates the capability of identifying radioactive 220Rn gas for environmental radiation monitoring applications. We believe that the exciton-harvesting strategy proposed here can greatly boost the applications of LDHs materials.
{"title":"Exciton-harvesting enabled efficient charged particle detection in zero-dimensional halides.","authors":"Qian Wang, Chenger Wang, Hongliang Shi, Jie Chen, Junye Yang, Alena Beitlerova, Romana Kucerkova, Zhengyang Zhou, Yunyun Li, Martin Nikl, Xilei Sun, Xiaoping OuYang, Yuntao Wu","doi":"10.1038/s41377-024-01532-z","DOIUrl":"10.1038/s41377-024-01532-z","url":null,"abstract":"<p><p>Materials for radiation detection are critically important and urgently demanded in diverse fields, starting from fundamental scientific research to medical diagnostics, homeland security, and environmental monitoring. Low-dimensional halides (LDHs) exhibiting efficient self-trapped exciton (STE) emission with high photoluminescence quantum yield (PLQY) have recently shown a great potential as scintillators. However, an overlooked issue of exciton-exciton interaction in LDHs under ionizing radiation hinders the broadening of its radiation detection applications. Here, we demonstrate an exceptional enhancement of exciton-harvesting efficiency in zero-dimensional (0D) Cs<sub>3</sub>Cu<sub>2</sub>I<sub>5</sub>:Tl halide single crystals by forming strongly localized Tl-bound excitons. Because of the suppression of non-radiative exciton-exciton interaction, an excellent α/β pulse-shape-discrimination (PSD) figure-of-merit (FoM) factor of 2.64, a superior rejection ratio of 10<sup>-9</sup>, and a high scintillation yield of 26 000 photons MeV<sup>-1</sup> under 5.49 MeV α-ray are achieved in Cs<sub>3</sub>Cu<sub>2</sub>I<sub>5</sub>:Tl single crystals, outperforming the commercial ZnS:Ag/PVT composites for charged particle detection applications. Furthermore, a radiation detector prototype based on Cs<sub>3</sub>Cu<sub>2</sub>I<sub>5</sub>:Tl single crystal demonstrates the capability of identifying radioactive <sup>220</sup>Rn gas for environmental radiation monitoring applications. We believe that the exciton-harvesting strategy proposed here can greatly boost the applications of LDHs materials.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-13DOI: 10.1038/s41377-024-01556-5
Zekun Niu, Hang Yang, Lyu Li, Minghui Shi, Guozhi Xu, Weisheng Hu, Lilin Yi
The surge in interest regarding the next generation of optical fiber transmission has stimulated the development of digital signal processing (DSP) schemes that are highly cost-effective with both high performance and low complexity. As benchmarks for nonlinear compensation methods, however, traditional DSP designed with block-by-block modules for linear compensations, could exhibit residual linear effects after compensation, limiting the nonlinear compensation performance. Here we propose a high-efficient design thought for DSP based on the learnable perspectivity, called learnable DSP (LDSP). LDSP reuses the traditional DSP modules, regarding the whole DSP as a deep learning framework and optimizing the DSP parameters adaptively based on backpropagation algorithm from a global scale. This method not only establishes new standards in linear DSP performance but also serves as a critical benchmark for nonlinear DSP designs. In comparison to traditional DSP with hyperparameter optimization, a notable enhancement of approximately 1.21 dB in the Q factor for 400 Gb/s signal after 1600 km fiber transmission is experimentally demonstrated by combining LDSP and perturbation-based nonlinear compensation algorithm. Benefiting from the learnable model, LDSP can learn the best configuration adaptively with low complexity, reducing dependence on initial parameters. The proposed approach implements a symbol-rate DSP with a small bit error rate (BER) cost in exchange for a 48% complexity reduction compared to the conventional 2 samples/symbol processing. We believe that LDSP represents a new and highly efficient paradigm for DSP design, which is poised to attract considerable attention across various domains of optical communications.
{"title":"Learnable digital signal processing: a new benchmark of linearity compensation for optical fiber communications.","authors":"Zekun Niu, Hang Yang, Lyu Li, Minghui Shi, Guozhi Xu, Weisheng Hu, Lilin Yi","doi":"10.1038/s41377-024-01556-5","DOIUrl":"10.1038/s41377-024-01556-5","url":null,"abstract":"<p><p>The surge in interest regarding the next generation of optical fiber transmission has stimulated the development of digital signal processing (DSP) schemes that are highly cost-effective with both high performance and low complexity. As benchmarks for nonlinear compensation methods, however, traditional DSP designed with block-by-block modules for linear compensations, could exhibit residual linear effects after compensation, limiting the nonlinear compensation performance. Here we propose a high-efficient design thought for DSP based on the learnable perspectivity, called learnable DSP (LDSP). LDSP reuses the traditional DSP modules, regarding the whole DSP as a deep learning framework and optimizing the DSP parameters adaptively based on backpropagation algorithm from a global scale. This method not only establishes new standards in linear DSP performance but also serves as a critical benchmark for nonlinear DSP designs. In comparison to traditional DSP with hyperparameter optimization, a notable enhancement of approximately 1.21 dB in the Q factor for 400 Gb/s signal after 1600 km fiber transmission is experimentally demonstrated by combining LDSP and perturbation-based nonlinear compensation algorithm. Benefiting from the learnable model, LDSP can learn the best configuration adaptively with low complexity, reducing dependence on initial parameters. The proposed approach implements a symbol-rate DSP with a small bit error rate (BER) cost in exchange for a 48% complexity reduction compared to the conventional 2 samples/symbol processing. We believe that LDSP represents a new and highly efficient paradigm for DSP design, which is poised to attract considerable attention across various domains of optical communications.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11319808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Augmented reality (AR) displays, heralded as the next-generation platform for spatial computing, metaverse, and digital twins, empower users to perceive digital images overlaid with real-world environment, fostering a deeper level of human-digital interactions. With the rapid evolution of couplers, waveguide-based AR displays have streamlined the entire system, boasting a slim form factor and high optical performance. However, challenges persist in the waveguide combiner, including low optical efficiency and poor image uniformity, significantly hindering the long-term usage and user experience. In this paper, we first analyze the root causes of the low optical efficiency and poor uniformity in waveguide-based AR displays. We then discover and elucidate an anomalous polarization conversion phenomenon inherent to polarization volume gratings (PVGs) when the incident light direction does not satisfy the Bragg condition. This new property is effectively leveraged to circumvent the tradeoff between in-coupling efficiency and eyebox uniformity. Through feasibility demonstration experiments, we measure the light leakage in multiple PVGs with varying thicknesses using a laser source and a liquid-crystal-on-silicon light engine. The experiment corroborates the polarization conversion phenomenon, and the results align with simulation well. To explore the potential of such a polarization conversion phenomenon further, we design and simulate a waveguide display with a 50° field of view. Through achieving first-order polarization conversion in a PVG, the in-coupling efficiency and uniformity are improved by 2 times and 2.3 times, respectively, compared to conventional couplers. This groundbreaking discovery holds immense potential for revolutionizing next-generation waveguide-based AR displays, promising a higher efficiency and superior image uniformity.
增强现实(AR)显示器被誉为空间计算、元宇宙和数字孪生的下一代平台,使用户能够感知与现实世界环境相叠加的数字图像,从而促进更深层次的人机交互。随着耦合器的快速发展,基于波导的 AR 显示器简化了整个系统,具有纤薄的外形和较高的光学性能。然而,波导合路器仍面临着光学效率低、图像均匀性差等挑战,严重影响了长期使用和用户体验。在本文中,我们首先分析了基于波导的 AR 显示屏光学效率低和均匀性差的根本原因。然后,我们发现并阐明了当入射光方向不满足布拉格条件时,偏振体积光栅(PVG)固有的异常偏振转换现象。利用这一新特性,可以有效规避内耦合效率和眼罩均匀性之间的权衡。通过可行性论证实验,我们利用激光源和硅基液晶光引擎测量了厚度不同的多个 PVG 的漏光情况。实验证实了偏振转换现象,结果与模拟结果吻合。为了进一步探索这种偏振转换现象的潜力,我们设计并模拟了一个视场角为 50° 的波导显示器。通过在 PVG 中实现一阶偏振转换,与传统耦合器相比,内耦合效率和均匀性分别提高了 2 倍和 2.3 倍。这一突破性发现为下一代基于波导的 AR 显示屏带来了巨大的变革潜力,有望实现更高的效率和卓越的图像均匀性。
{"title":"Breaking the in-coupling efficiency limit in waveguide-based AR displays with polarization volume gratings.","authors":"Yuqiang Ding, Yuchen Gu, Qian Yang, Zhiyong Yang, Yuge Huang, Yishi Weng, Yuning Zhang, Shin-Tson Wu","doi":"10.1038/s41377-024-01537-8","DOIUrl":"10.1038/s41377-024-01537-8","url":null,"abstract":"<p><p>Augmented reality (AR) displays, heralded as the next-generation platform for spatial computing, metaverse, and digital twins, empower users to perceive digital images overlaid with real-world environment, fostering a deeper level of human-digital interactions. With the rapid evolution of couplers, waveguide-based AR displays have streamlined the entire system, boasting a slim form factor and high optical performance. However, challenges persist in the waveguide combiner, including low optical efficiency and poor image uniformity, significantly hindering the long-term usage and user experience. In this paper, we first analyze the root causes of the low optical efficiency and poor uniformity in waveguide-based AR displays. We then discover and elucidate an anomalous polarization conversion phenomenon inherent to polarization volume gratings (PVGs) when the incident light direction does not satisfy the Bragg condition. This new property is effectively leveraged to circumvent the tradeoff between in-coupling efficiency and eyebox uniformity. Through feasibility demonstration experiments, we measure the light leakage in multiple PVGs with varying thicknesses using a laser source and a liquid-crystal-on-silicon light engine. The experiment corroborates the polarization conversion phenomenon, and the results align with simulation well. To explore the potential of such a polarization conversion phenomenon further, we design and simulate a waveguide display with a 50° field of view. Through achieving first-order polarization conversion in a PVG, the in-coupling efficiency and uniformity are improved by 2 times and 2.3 times, respectively, compared to conventional couplers. This groundbreaking discovery holds immense potential for revolutionizing next-generation waveguide-based AR displays, promising a higher efficiency and superior image uniformity.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141917028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shack-Hartmann wavefront sensors measure the local slopes of an incoming wavefront based on the displacement of focal spots created by a lenslet array, serving as key components for adaptive optics for astronomical and biomedical imaging. Traditionally, the challenges in increasing the density and the curvature of the lenslet have limited the use of such wavefront sensors in characterizing slowly varying wavefront structures. Here, we develop a metasurface-enhanced Shack-Hartmann wavefront sensor (meta SHWFS) to break this limit, considering the interplay between the lenslet parameters and the performance of SHWFS. We experimentally validate the meta SHWFS with a sampling density of 5963 per mm2 and a maximum acceptance angle of 8° which outperforms the traditional SFWFS by an order of magnitude. Furthermore, to the best of our knowledge, we demonstrate the first use of a wavefront sensing scheme in single-shot phase imaging of highly complex patterns, including biological tissue patterns. The proposed approach opens up new opportunities in incorporating exceptional light manipulation capabilities of the metasurface platform in complex wavefront characterization.
{"title":"Meta Shack-Hartmann wavefront sensor with large sampling density and large angular field of view: phase imaging of complex objects.","authors":"Gi-Hyun Go, Dong-Gu Lee, Jaeyeon Oh, Gookho Song, Doeon Lee, Mooseok Jang","doi":"10.1038/s41377-024-01528-9","DOIUrl":"10.1038/s41377-024-01528-9","url":null,"abstract":"<p><p>Shack-Hartmann wavefront sensors measure the local slopes of an incoming wavefront based on the displacement of focal spots created by a lenslet array, serving as key components for adaptive optics for astronomical and biomedical imaging. Traditionally, the challenges in increasing the density and the curvature of the lenslet have limited the use of such wavefront sensors in characterizing slowly varying wavefront structures. Here, we develop a metasurface-enhanced Shack-Hartmann wavefront sensor (meta SHWFS) to break this limit, considering the interplay between the lenslet parameters and the performance of SHWFS. We experimentally validate the meta SHWFS with a sampling density of 5963 per mm<sup>2</sup> and a maximum acceptance angle of 8° which outperforms the traditional SFWFS by an order of magnitude. Furthermore, to the best of our knowledge, we demonstrate the first use of a wavefront sensing scheme in single-shot phase imaging of highly complex patterns, including biological tissue patterns. The proposed approach opens up new opportunities in incorporating exceptional light manipulation capabilities of the metasurface platform in complex wavefront characterization.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11319597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-12DOI: 10.1038/s41377-024-01505-2
Tianyu Zhao, Ming Lei
Parallel acquisition-readout structured-illumination microscopy (PAR-SIM) was designed for high-speed raw data acquisition. By utilizing an xy-scan galvo mirror set, the raw data is projected onto different areas of the camera, enabling a fundamentally stupendous information spatial-temporal flux.
{"title":"Fast, faster, and the fastest structured illumination microscopy.","authors":"Tianyu Zhao, Ming Lei","doi":"10.1038/s41377-024-01505-2","DOIUrl":"10.1038/s41377-024-01505-2","url":null,"abstract":"<p><p>Parallel acquisition-readout structured-illumination microscopy (PAR-SIM) was designed for high-speed raw data acquisition. By utilizing an xy-scan galvo mirror set, the raw data is projected onto different areas of the camera, enabling a fundamentally stupendous information spatial-temporal flux.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11319336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01DOI: 10.1038/s41377-024-01539-6
Yang Lu, Xu Zhao, Dongmei Yan, Yingqian Mi, Peng Sun, Xu Yan, Xiaomin Liu, Geyu Lu
Chiral assemblies have become one of the most active research areas due to their versatility, playing an increasingly important role in bio-detection, imaging and therapy. In this work, chiral UCNPs/CuxOS@ZIF nanoprobes are prepared by encapsulating upconversion nanoparticles (UCNPs) and CuxOS nanoparticles (NPs) into zeolitic imidazolate framework-8 (ZIF-8). The novel excited-state energy distribution-modulated upconversion nanostructure (NaYbF4@NaYF4: Yb, Er) is selected as the fluorescence source and energy donor for highly efficient fluorescence resonance energy transfer (FRET). CuxOS NP is employed as chiral source and energy acceptor to quench upconversion luminescence (UCL) and provide circular dichroism (CD) signal. Utilizing the natural adsorption and sorting advantages of ZIF-8, the designed nanoprobe can isolate the influence of other common disruptors, thus achieve ultra-sensitive and highly selective UCL/CD dual-mode quantification of H2S in aqueous solution and in living cells. Notably, the nanoprobe is also capable of in vivo intra-tumoral H2S tracking. Our work highlights the multifunctional properties of chiral nanocomposites in sensing and opens a new vision and idea for the preparation and application of chiral nanomaterials in biomedical and biological analysis.
{"title":"Upconversion-based chiral nanoprobe for highly selective dual-mode sensing and bioimaging of hydrogen sulfide in vitro and in vivo.","authors":"Yang Lu, Xu Zhao, Dongmei Yan, Yingqian Mi, Peng Sun, Xu Yan, Xiaomin Liu, Geyu Lu","doi":"10.1038/s41377-024-01539-6","DOIUrl":"10.1038/s41377-024-01539-6","url":null,"abstract":"<p><p>Chiral assemblies have become one of the most active research areas due to their versatility, playing an increasingly important role in bio-detection, imaging and therapy. In this work, chiral UCNPs/Cu<sub>x</sub>OS@ZIF nanoprobes are prepared by encapsulating upconversion nanoparticles (UCNPs) and Cu<sub>x</sub>OS nanoparticles (NPs) into zeolitic imidazolate framework-8 (ZIF-8). The novel excited-state energy distribution-modulated upconversion nanostructure (NaYbF<sub>4</sub>@NaYF<sub>4</sub>: Yb, Er) is selected as the fluorescence source and energy donor for highly efficient fluorescence resonance energy transfer (FRET). Cu<sub>x</sub>OS NP is employed as chiral source and energy acceptor to quench upconversion luminescence (UCL) and provide circular dichroism (CD) signal. Utilizing the natural adsorption and sorting advantages of ZIF-8, the designed nanoprobe can isolate the influence of other common disruptors, thus achieve ultra-sensitive and highly selective UCL/CD dual-mode quantification of H<sub>2</sub>S in aqueous solution and in living cells. Notably, the nanoprobe is also capable of in vivo intra-tumoral H<sub>2</sub>S tracking. Our work highlights the multifunctional properties of chiral nanocomposites in sensing and opens a new vision and idea for the preparation and application of chiral nanomaterials in biomedical and biological analysis.</p>","PeriodicalId":18093,"journal":{"name":"Light, science & applications","volume":null,"pages":null},"PeriodicalIF":19.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141875274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}