Pub Date : 2022-12-01DOI: 10.21608/mjmu.2022.129215.1088
Youssef El Sabbagh, O. Hamdy
In the last 20 years, axillary surgery for breast cancer has changed dramatically. In clinically node-positive patients, ALND is the conventional procedure. With the development of efficient neo-adjuvant chemotherapy (NACT), there is a shift toward less aggressive operation in patients who have clinical signs of excellent response and disease shrinkage. Therefore, SLN biopsy (SLNB), which offers an accurate, less morbid staging procedure that prevents complications of ALND has become the standard technique in node negative early breast cancer. In these patients, However, there has been a reluctance to perform (SLNB) after completion of NACT in patients with histologically proven axillary metastases because of false-negative rates (FNRs) greater than 10%. To deal with this problem, a new and promising technique called targeted axillary dissection (TAD) has been developed for determining axillary status in postneoadjuvant chemotherapy (NACT) node-positive breast cancer patients. It includes removal of the SLN as well as the pathologically proven positive nodes which have to be marked before starting the NACT. TAD can be considered a practical, reproducible, and valid method for ruling out metastatic axillary involvement in patients with breast cancer who have had a favourable response to NACT
{"title":"Targeted Axillary Dissection In Breast Cancer Patients After Neoadjuvant Therapy","authors":"Youssef El Sabbagh, O. Hamdy","doi":"10.21608/mjmu.2022.129215.1088","DOIUrl":"https://doi.org/10.21608/mjmu.2022.129215.1088","url":null,"abstract":"In the last 20 years, axillary surgery for breast cancer has changed dramatically. In clinically node-positive patients, ALND is the conventional procedure. With the development of efficient neo-adjuvant chemotherapy (NACT), there is a shift toward less aggressive operation in patients who have clinical signs of excellent response and disease shrinkage. Therefore, SLN biopsy (SLNB), which offers an accurate, less morbid staging procedure that prevents complications of ALND has become the standard technique in node negative early breast cancer. In these patients, However, there has been a reluctance to perform (SLNB) after completion of NACT in patients with histologically proven axillary metastases because of false-negative rates (FNRs) greater than 10%. To deal with this problem, a new and promising technique called targeted axillary dissection (TAD) has been developed for determining axillary status in postneoadjuvant chemotherapy (NACT) node-positive breast cancer patients. It includes removal of the SLN as well as the pathologically proven positive nodes which have to be marked before starting the NACT. TAD can be considered a practical, reproducible, and valid method for ruling out metastatic axillary involvement in patients with breast cancer who have had a favourable response to NACT","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80575477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/mjmu.2022.128482.1070
ِEsraa Elamli, M. E. El Fahar
Primary cleft rhinoplasty has been a topic of interest over the decades. The cleft nasal deformities challenge all plastic surgeons. There is significant variability in the anatomy of each cleft deformity, but iatrogenic changes and scarring from the previous surgeries add another layer of complexity. There are lots of techniques described to address such deformities. These techniques were further refined and modified over time, but no one protocol is reported to be entirely satisfactory. A perfect nose with no deformity is unusual, but reasonably good results are achieved when the principles of nasal repair are fully applied. Moreover, there is still paucity in the outcomes reported, which makes it harder to evaluate the results of the primary rhinoplasty. And, even the few reported results are not evaluated according to standardized methods, making the evaluation subjective. This work aims to review recent literature on long-term primary rhinoplasty outcomes of unilateral cleft lip.
{"title":"An Update on the Outcome of Primary Cleft Rhinoplasty","authors":"ِEsraa Elamli, M. E. El Fahar","doi":"10.21608/mjmu.2022.128482.1070","DOIUrl":"https://doi.org/10.21608/mjmu.2022.128482.1070","url":null,"abstract":"Primary cleft rhinoplasty has been a topic of interest over the decades. The cleft nasal deformities challenge all plastic surgeons. There is significant variability in the anatomy of each cleft deformity, but iatrogenic changes and scarring from the previous surgeries add another layer of complexity. There are lots of techniques described to address such deformities. These techniques were further refined and modified over time, but no one protocol is reported to be entirely satisfactory. A perfect nose with no deformity is unusual, but reasonably good results are achieved when the principles of nasal repair are fully applied. Moreover, there is still paucity in the outcomes reported, which makes it harder to evaluate the results of the primary rhinoplasty. And, even the few reported results are not evaluated according to standardized methods, making the evaluation subjective. This work aims to review recent literature on long-term primary rhinoplasty outcomes of unilateral cleft lip.","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82426741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/mjmu.2022.160761.1142
Hoda M. Sobh, maged zaghlool, insaf elnady, ahmed hataha
Background: Biphasic responses to ventricular premature contractions (VPCs) cause heart rate turbulence (HRT), which is primarily mediated by the baroreceptors. HRT is useful for cardiovascular risk stratification of different cardiac diseases. Aim and objectives: The purpose of this research was to analyze HRT in patients with chronic Aortic regurgitation (AR) and determine whether there is a correlation between HRT parameters and echocardiographic data. Subjects and methods: This case control study was carried out in Specialized Medical Hospital, Cardiology Department, Mansoura University on 30 aortic regurgitation patients and other 30 control individuals. HRT parameters were compared in both groups. Result: There was a positive correlation between turbulence slope (TS) and ejection fraction (EF), Fractional shortening (FS). There was a positive correlation between turbulence onset (TO) and min heart rate (HR), and TS with time domain SDANN. Conclusion: Patients with chronic AR had significantly impaired HRT parameters compared to normal subjects.
{"title":"Dynamics of spontaneous heart rate turbulence in patients with pure chronic aortic regurgitation","authors":"Hoda M. Sobh, maged zaghlool, insaf elnady, ahmed hataha","doi":"10.21608/mjmu.2022.160761.1142","DOIUrl":"https://doi.org/10.21608/mjmu.2022.160761.1142","url":null,"abstract":"Background: Biphasic responses to ventricular premature contractions (VPCs) cause heart rate turbulence (HRT), which is primarily mediated by the baroreceptors. HRT is useful for cardiovascular risk stratification of different cardiac diseases. Aim and objectives: The purpose of this research was to analyze HRT in patients with chronic Aortic regurgitation (AR) and determine whether there is a correlation between HRT parameters and echocardiographic data. Subjects and methods: This case control study was carried out in Specialized Medical Hospital, Cardiology Department, Mansoura University on 30 aortic regurgitation patients and other 30 control individuals. HRT parameters were compared in both groups. Result: There was a positive correlation between turbulence slope (TS) and ejection fraction (EF), Fractional shortening (FS). There was a positive correlation between turbulence onset (TO) and min heart rate (HR), and TS with time domain SDANN. Conclusion: Patients with chronic AR had significantly impaired HRT parameters compared to normal subjects.","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"2020 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87859350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-27DOI: 10.21608/mvmj.2022.162138.1121
Eman A. Abo Elfadl, H. Radwan, U. Abou-Ismail
{"title":"Differentiation and classification of productive efficiency of chicken farms using logistic regression and linear discriminant analysis","authors":"Eman A. Abo Elfadl, H. Radwan, U. Abou-Ismail","doi":"10.21608/mvmj.2022.162138.1121","DOIUrl":"https://doi.org/10.21608/mvmj.2022.162138.1121","url":null,"abstract":"","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91222273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-24DOI: 10.21608/mvmj.2022.120462.1102
Mohamed K. Abdeldayem, S. Zaabel, Magdy Badr, Heba A Sharawy, Amira Mostagir, Fatma Adlan, R. Saleh, M. Elmetwally
{"title":"Effects of L arginine supplementation on in-vitro maturation and cryotolerance of immature buffalo oocyte","authors":"Mohamed K. Abdeldayem, S. Zaabel, Magdy‎ Badr, Heba A Sharawy, Amira Mostagir, Fatma Adlan, R. Saleh, M. Elmetwally","doi":"10.21608/mvmj.2022.120462.1102","DOIUrl":"https://doi.org/10.21608/mvmj.2022.120462.1102","url":null,"abstract":"","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88883630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-18DOI: 10.21608/mvmj.2022.160242.1119
T. Fathy, Amira I. Zakaria, S. Abd-Elghany, K. Sallam
{"title":"Prevalence, genetic characterization, and antibiogram of Salmonella enterica recovered from buffalo meat","authors":"T. Fathy, Amira I. Zakaria, S. Abd-Elghany, K. Sallam","doi":"10.21608/mvmj.2022.160242.1119","DOIUrl":"https://doi.org/10.21608/mvmj.2022.160242.1119","url":null,"abstract":"","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78337699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.21608/mjmu.2022.132170.1094
A. bedier, Sally Teima, A. Elshal
Background: Atrial fibrillation (AF) is the most typical sustained cardiac disturbance all over the world, it increases the risk of left atrial (LA) thrombus, Plasma fibrin D-dimers seems to be a helpful parameter for assessing the degrees of hypercoagulability. Higher risk of recurrent ischemic stroke was found to be associated with baseline elevated D-dimers levels. Aim: To assess the value of D-Dimer examination in prediction of presence of LA thrombus in patients with AF instead of transesophageal echocardiography (TEE) examination. Patients and Methods: Analytical cross-sectional study was conducted. It included 250 patients divided according to presence of LA thrombus into two groups; group without LA thrombus (n=224), and group with LA thrombus (n=26), referred to cardiology department, Mansoura Specialized Medicine Hospital. History was taken, blood was collected for D-dimer testing on the same day of the TEE. Results: CHADS2-VASc, Heart failure, Diastolic dysfunction, D-dimers (ng/mL), D Dimer more than 500 ng/mL, and D Dimer more than 10×patient’s age have positive and statistically significant impact on LA thrombus formation. Similarly, Paroxysmal AF and left ventricle ejection fraction (%) had negative and statistically significant impact on LA thrombus formation. The optimal cutoff point of D-dimers was 1247.9 (ng/mL), its accuracy was 86.4%, (AUC = 0.711) with sensitivity (50%) and specificity (90.6%). Conclusion: D-dimer can be beneficial in clinical practice to exclude LA thrombus avoiding TEE, particularly in patients with low thromboembolic risk such as normal left atrial dimensions, no previous attacks of AF, no valvular heart disease, female patient, CHAD2VASC score less than 2 and no history of thromboembolic attacks.
{"title":"The Value of D-Dimer Blood Concentrations in Prediction of Presence of Left Atrial Thrombus in Patients with non-valvular Atrial Fibrillation","authors":"A. bedier, Sally Teima, A. Elshal","doi":"10.21608/mjmu.2022.132170.1094","DOIUrl":"https://doi.org/10.21608/mjmu.2022.132170.1094","url":null,"abstract":"Background: Atrial fibrillation (AF) is the most typical sustained cardiac disturbance all over the world, it increases the risk of left atrial (LA) thrombus, Plasma fibrin D-dimers seems to be a helpful parameter for assessing the degrees of hypercoagulability. Higher risk of recurrent ischemic stroke was found to be associated with baseline elevated D-dimers levels. Aim: To assess the value of D-Dimer examination in prediction of presence of LA thrombus in patients with AF instead of transesophageal echocardiography (TEE) examination. Patients and Methods: Analytical cross-sectional study was conducted. It included 250 patients divided according to presence of LA thrombus into two groups; group without LA thrombus (n=224), and group with LA thrombus (n=26), referred to cardiology department, Mansoura Specialized Medicine Hospital. History was taken, blood was collected for D-dimer testing on the same day of the TEE. Results: CHADS2-VASc, Heart failure, Diastolic dysfunction, D-dimers (ng/mL), D Dimer more than 500 ng/mL, and D Dimer more than 10×patient’s age have positive and statistically significant impact on LA thrombus formation. Similarly, Paroxysmal AF and left ventricle ejection fraction (%) had negative and statistically significant impact on LA thrombus formation. The optimal cutoff point of D-dimers was 1247.9 (ng/mL), its accuracy was 86.4%, (AUC = 0.711) with sensitivity (50%) and specificity (90.6%). Conclusion: D-dimer can be beneficial in clinical practice to exclude LA thrombus avoiding TEE, particularly in patients with low thromboembolic risk such as normal left atrial dimensions, no previous attacks of AF, no valvular heart disease, female patient, CHAD2VASC score less than 2 and no history of thromboembolic attacks.","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"137 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80091388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.21608/mjmu.2022.129792.1092
heba aldegla, Ali Elzar, A. Eldeeb
According to WHO Coronavirus (COVID-19) Dashboard, as of 11 th February 2022, there have been 404,910,528 confirmed cases of COVID-19, including 5,783,776 deaths. Coronavirus-2 (SARS-CoV-2) is the causative agent. It is caused by coronavirus-2 (SARS-CoV-2), the disease may cause acute respiratory distress syndrome (ARDS), that increases the susceptibility of co-infections with fungi. Acute invasive fungal sinusitis (AIFS) is a severe infection mostly affecting immune-compromised patients and carries high risk of mortality. COVID-19 patients admitted to the ICU have risk factors for AIFS, mainly chronic diseases of the respiratory tract, treatment with corticosteroid, intubation/mechanical ventilation, and cytokine storm. Aspergillus and Mucorales are the causative fungi of most AIFS cases, but other atypical fungi can be involved especially among patients receiving azole prophylaxis. Most AIFS cases have symptoms like fever, nasal congestion, and facial swelling. Diagnosis of AIFS is made by endoscopy and radiology associated with clinical examination. The gold standard test for diagnosis of AIFS is histopathology, though pan-fungal PCR plays an important role. Therapy of AIFS includes surgery, antifungal agents, and correction of immunosuppression status
{"title":"Invasive Fungal Sinusitis Associated with COVID-19","authors":"heba aldegla, Ali Elzar, A. Eldeeb","doi":"10.21608/mjmu.2022.129792.1092","DOIUrl":"https://doi.org/10.21608/mjmu.2022.129792.1092","url":null,"abstract":"According to WHO Coronavirus (COVID-19) Dashboard, as of 11 th February 2022, there have been 404,910,528 confirmed cases of COVID-19, including 5,783,776 deaths. Coronavirus-2 (SARS-CoV-2) is the causative agent. It is caused by coronavirus-2 (SARS-CoV-2), the disease may cause acute respiratory distress syndrome (ARDS), that increases the susceptibility of co-infections with fungi. Acute invasive fungal sinusitis (AIFS) is a severe infection mostly affecting immune-compromised patients and carries high risk of mortality. COVID-19 patients admitted to the ICU have risk factors for AIFS, mainly chronic diseases of the respiratory tract, treatment with corticosteroid, intubation/mechanical ventilation, and cytokine storm. Aspergillus and Mucorales are the causative fungi of most AIFS cases, but other atypical fungi can be involved especially among patients receiving azole prophylaxis. Most AIFS cases have symptoms like fever, nasal congestion, and facial swelling. Diagnosis of AIFS is made by endoscopy and radiology associated with clinical examination. The gold standard test for diagnosis of AIFS is histopathology, though pan-fungal PCR plays an important role. Therapy of AIFS includes surgery, antifungal agents, and correction of immunosuppression status","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90279108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-01DOI: 10.21608/mjmu.2022.150095.1128
Mohamed M Elsherbini, M. Elhawary, K. Ali, A. Elmokadem, A. Khalil, M. Elshirbiny
The purpose of this study is to discuss the clinical, radiological and histopathological features of a rare grade 2 variant of meningioma. Patients and methods: A retrospective analysis of the data of 6 patients who underwent surgery for a histopathologically proven chodroid meningioma. Results: Six patients’ pathology reports showed chordoid meningioma. On imaging, four lesions (67%) were isointense in T1 while the other two were hypointense. On T2 weighted images, four patients were hyperintense (67%) and displayed non-restricted diffusion pattern with elevated values on corresponding apparent diffusion coefficient maps. Pathologically, chordoid elements varied vastly among cases, radiological characters corresponded to choroid elements in all cases. Conclusion: choirdoid meningioma, as a rare meningioma entity, should be suspected pre-operatively in cases with high signal intensity in T2, homogenous enhancement and increased apparent diffusion coefficient, gross total surgical excision is curative.
{"title":"Chordoid Meningioma: Clinical, Hsitopathological and Radiological Study","authors":"Mohamed M Elsherbini, M. Elhawary, K. Ali, A. Elmokadem, A. Khalil, M. Elshirbiny","doi":"10.21608/mjmu.2022.150095.1128","DOIUrl":"https://doi.org/10.21608/mjmu.2022.150095.1128","url":null,"abstract":"The purpose of this study is to discuss the clinical, radiological and histopathological features of a rare grade 2 variant of meningioma. Patients and methods: A retrospective analysis of the data of 6 patients who underwent surgery for a histopathologically proven chodroid meningioma. Results: Six patients’ pathology reports showed chordoid meningioma. On imaging, four lesions (67%) were isointense in T1 while the other two were hypointense. On T2 weighted images, four patients were hyperintense (67%) and displayed non-restricted diffusion pattern with elevated values on corresponding apparent diffusion coefficient maps. Pathologically, chordoid elements varied vastly among cases, radiological characters corresponded to choroid elements in all cases. Conclusion: choirdoid meningioma, as a rare meningioma entity, should be suspected pre-operatively in cases with high signal intensity in T2, homogenous enhancement and increased apparent diffusion coefficient, gross total surgical excision is curative.","PeriodicalId":18173,"journal":{"name":"Mansoura Veterinary Medical Journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86158384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}