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Magnetic resonance elastography: a review 磁共振弹性成像:综述
Pub Date : 2015-11-02 DOI: 10.12775/MBS.2015.025
Grażyna Rusak, E. Zawada
Elastografia rezonansu magnetycznego (MRE) jest szybko rozwijającą sie, nieinwazyjną, dokladną i odtwarzalną metoda diagnostyczną, wykorzystywaną dla obrazowania wlasności mechanicznych tkanek oraz dla ilościowej oceny propagacji fal sprezystych w  badanych tkankach. Zasadniczo technika ta sklada sie z trzech podstawowych krokow. Po pierwsze generowanie w obszarze zainteresowania fal sprezystych o czestotliwości w zakresie 50-5000 Hz. Nastepnie pozyskiwanie obrazow rezonansu magnetycznego, ktore przedstawiają rozchodzenie sie wyindukowanych fal sprezystych. Ostatecznie przetwarzanie obrazow szerzenia sie fal sprezystych na ilościowe mapy sztywności tkanek zwane elastogramami. MRE umozliwia wykrywanie i stopniowanie przewle-klego wloknienia wątroby. Sekwencja moze byc wyko-rzystywana dla monitorowani odpowiedzi na leczenie lub dla oceny progresji choroby. Trwają badania naukowe z uzyciem elastografii rezo-nansu magnetycznego w ocenie innych organow takich jak serce, piersi, pluca, nerki, prostata, tkanka mozgowa i rdzen kregowy, uklad mieśniowo-szkieletowy.
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引用次数: 0
Dizziness in older people 老年人的头晕
Pub Date : 2015-11-02 DOI: 10.12775/MBS.2015.023
Grzegorz Sielski, M. Sielska, Marta Podhorecka, Dominika Gębka, Marta Sucharska-Szymkowiak, Natalia Ciesielska, Łukasz Rolka, K. Porzych, K. Kędziora–Kornatowska
Dizziness is a very common disorder, and its incidence increases with age. It is a symptom of disorder not the essence of the disease. It is usually the result of disorders of the vestibular system, and can be caused by damage to the labyrinth (vertigo) or its innervation (dizziness). Dizziness deals with two areas of medicine - otolaryngology and neurology. Borderland  of these specialties is neurotology, which has been recently considered as a separate specialty. However, it is difficult to diagnose and treat the causes of dizziness and often beyond the otolaryngologist and neurologist  close cooperation of other professionals such as: a cardiologist, ophthalmologist, radiologist, orthopedist, and even a psychiatrist is required. Dizziness is a hardly perceptible symptom and usually very difficult to diagnose. In older persons dizziness occurs due to many different reasons of central, peripheral or psychiatric nature as well as on a background of variety of systemic diseases. Best pharmacological treatment should be started after the appropriate diagnostics and after proper diagnosis. If the cause of dizziness is vestibular system, customized exercise can have a very beneficial effect on the recovery of functional capacity.
头晕是一种非常常见的疾病,其发病率随着年龄的增长而增加。它是疾病的症状,而不是疾病的本质。它通常是前庭系统紊乱的结果,可由迷路(眩晕)或其神经支配(头晕)的损害引起。头晕涉及两个医学领域——耳鼻喉科和神经病学。这些专业的边界是神经病学,最近被认为是一个独立的专业。然而,头晕的病因很难诊断和治疗,往往需要耳鼻喉科医生和神经科医生等其他专业人士的密切合作,如:心脏病专家、眼科医生、放射科医生、骨科医生,甚至精神科医生。头晕是一种难以察觉的症状,通常很难诊断。在老年人中,由于中枢、外周或精神性质的许多不同原因以及各种全身性疾病的背景而发生头晕。最好的药物治疗应在适当的诊断和正确的诊断后开始。如果头晕的原因是前庭系统,定制运动可以对功能能力的恢复有非常有益的作用。
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引用次数: 0
Biological and anticancer activity of selected natural products 选定的天然产物的生物学和抗癌活性
Pub Date : 2015-10-29 DOI: 10.12775/MBS.2015.026
M. Matejczyk
Cancer continues to be one of the major causes of death worldwide. In recent years, the concept of cancer chemoprevention and treatment with natural occurring agents has evolved greatly. In this review work the biological activity and protective effects against cancer of some  natural products - coffee, caffeic acid, caffeic acid phenethyl ester ( CAPE), chlorogenic acid, quercetin and curcumin are presented. It seems that the most natural products with anticancer activity act as strong antioxidants and/or modify the activity of one or more protein kinases involved in cell cycle control. The results of in vitro and in vivo studies showed that some of them may be useful as potential chemotherapeutic or chemopreventive anticancer drugs or adjuvants in complex anticancer therapy.
癌症仍然是全世界死亡的主要原因之一。近年来,癌症化学预防和天然药物治疗的概念有了很大的发展。本文综述了咖啡、咖啡酸、咖啡酸苯乙酯(CAPE)、绿原酸、槲皮素和姜黄素等天然产物的生物活性和抗癌作用。似乎大多数具有抗癌活性的天然产物作为强抗氧化剂和/或改变参与细胞周期控制的一种或多种蛋白激酶的活性。体外和体内研究结果表明,其中一些可能作为潜在的化疗或化学预防抗癌药物或辅助药物用于复杂的抗癌治疗。
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引用次数: 3
Primary hyperparathyroidism and cardiovascular risk. Is there a connection 原发性甲状旁腺功能亢进与心血管风险。这两者之间有联系吗?
Pub Date : 2015-08-01 DOI: 10.20286/NOVA-JMBS-040263
T. Delistathi, H. Markogiannakis, D. Tsamis, A. Manouras, I. Giotakis, G. Zografos
In primary hyperparathyroidism parathormone (ΡΤΗ) is secreted autonomously and produce increase of calcium and decrease of phosphorus in the serum of the affected patients.In this study the newer facts in the medical literature about the influence of primary hyperparathyroidism in cardiovascular system are presented. Big studies have investigated the role of several factors affected in primary hyperparathyroidism. It seems that the increase of PTH affects the cardiovascular system in various ways. But there is a debate about the mild cases of hyperparathyroidism and short-standing disease.
原发性甲状旁腺功能亢进症患者的甲状旁腺激素(ΡΤΗ)是自主分泌的,在患者血清中引起钙升高和磷降低。本文介绍了医学文献中有关原发性甲状旁腺功能亢进对心血管系统影响的最新事实。大型研究调查了影响原发性甲状旁腺功能亢进的几个因素的作用。似乎甲状旁腺激素的增加会以多种方式影响心血管系统。但是关于甲状旁腺功能亢进和短期疾病的轻度病例存在争议。
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引用次数: 1
Physicochemical and Spectroscopic Evaluation of Adsorption potentials of Activated Charcoal from stem parts of Mangifera indica, Persea gratissima and Psidium guajava for Pharmaceutical medicine 活性炭对芒果、洋槐和番石榴茎部分药用药物的吸附电位的理化和光谱评价
Pub Date : 2015-08-01 DOI: 10.20286/NOVA-JMBS-040237
Edwin N. Oguegbulu, E. Nwoke
Activated charcoal which comes in synonyms of; carbon, charcoal, medicoal and Norit is very useful in the field of pharmaceutical medicine and in industries. The medicoal samples were sourced for this study from Nigerian plants, namely; Mangifera indica (Mangoe tree), Psidium guajara (Guava tree) and Persea gratissima (Avocado tree). Samples were prepared by carbonization and thermal activation prior to characterization evidence such as percentage of carbonized residues, ash values, fixed carbon contents, pH of aqueous solution, and limits of heavy metal presence. Liquid phase study was conducted by adoption of Freundlich adsorption model. Following this, data were generated for adsorption profile of methylene Blue (MB) on the various samples of activated charcoal inclusive of the commercial grade (standard). Ultra violet spectroscopy was used to measure the respective adsorption capacities. The results were statistically significant using a one-tail (ANOVA) at confidence level of P < 0.05. Persea gratissima ranked the highest in performance out of the three test samples with MB adsorption (9.95 mg/g) and compared favourably with the standard (9.96mg/g). Psidium guajava exhibited the least performance (1.04mg/g). All samples showed desirable aqueous pH of range (6-8). The research has shown that low cost and easily accessible, locally sourced activated charcoal is a recommendable alternative to the commercially available products.
活性炭的同义词是;碳,木炭,医疗和Norit在医药和工业领域非常有用。本研究的药物样本来自尼日利亚植物,即;Mangifera indica(芒果树),Psidium guajara(番石榴树)和Persea gratissima(鳄梨树)。样品通过炭化和热活化制备,然后进行表征证据,如炭化残留物的百分比,灰分值,固定碳含量,水溶液的pH值和重金属存在的限制。液相研究采用Freundlich吸附模型。在此之后,生成了亚甲基蓝(MB)在各种活性炭样品上的吸附曲线数据,包括商业级(标准)。采用紫外光谱法测定了其吸附量。采用单尾方差分析(ANOVA),置信水平P < 0.05,结果具有统计学意义。在三个测试样品中,紫花苜蓿对MB的吸附性能最高(9.95 mg/g),优于标准样品(9.96mg/g)。瓜爪哇紫丁香的活性最低,为1.04mg/g。所有样品的水溶液pH值范围为(6-8)。研究表明,低成本和容易获得的本地采购的活性炭是一种值得推荐的替代品,可以替代市售产品。
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引用次数: 1
Antimicrobial activities of Syzygium cumini leave extracts against selected microorganisms 茴香叶提取物对特定微生物的抑菌活性研究
Pub Date : 2015-08-01 DOI: 10.20286/NOVA-JMBS-040245
A. Elfadil, Awad Abdalfattah karamallah, A. M. Abualhassan, A. A. Hamid, M. Sabahelkhier.
Leaves extracts of Syzygium cumini (L) were collected to test their antimicrobial activity. The collected materials were extracted by petroleum ether, methanol and water by using different concentration (15% 10% and 5%). Were obtained and bioassay in vitro for its bioactivity to inhabit the growth of four types of bacteria,namely; ( Staphlococcus aureus , Escherichia coli , Pseudomonas aeruginosa , and Bacillus subitils ) and two types of fungi ( Aspergillus niger , and Candida albicans) . The extract of Syzygium cumini leaves showed different activity against the selected bacteria at all concentration levels. By using cup plate diffusion method, petroleum ether extract of Syzygium cumini leaves showed activity against E . coli only. Methanol extract showed variable activity against bacteria in different concentrations especially 15% concentration showed high activity against B. subtilis . Water extract showed variable activity against most of the tested bacteria. E. coli was found to be sensitive to all concentrations.
本文收集芫荽(Syzygium cumini, L)叶提取物,测定其抑菌活性。用石油醚、甲醇和水分别以不同浓度(15%、10%和5%)进行萃取。分别获得并测定其在体外对四种细菌生长的生物活性,即;(金黄色葡萄球菌、大肠杆菌、铜绿假单胞菌和枯草芽孢杆菌)和两种真菌(黑曲霉和白色念珠菌)。在不同浓度下,菟丝子叶提取物对所选细菌的活性不同。用杯盘扩散法测定了菟丝子叶石油醚提取物对大肠杆菌的抑菌活性。杆菌。甲醇提取物在不同浓度下的抑菌活性不同,其中15%浓度对枯草芽孢杆菌抑菌活性较高。水提取物对大多数被试细菌表现出不同的活性。大肠杆菌被发现对所有浓度都敏感。
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引用次数: 9
Ecological problem of Azerbaijan sector of the Caspian Sea 里海阿塞拜疆部分的生态问题
Pub Date : 2015-08-01 DOI: 10.20286/NOVA-JMBS-040239
S. Salahova, S. Topchiyeva, I.Kh. Alakbarov
The article presented the results of analyzes of heavy metals in the water, which has taken from the area of oil and gas fields ("Oil Rocks", "Gyarbi Absheron", "Absheron Bankasi" and "Bulla") of the Azerbaijan sector of the Caspian Sea seasonally from 2011 to 2013. Identify the exceeding average level of permissible concentration for iron, zinc, copper; their values corresponded to Fe (0,163-0,197 mg/L) at the MPC 0.05 mg/L, Zn (0,141-0,171 mg/L) at the MPC 0.01-0.05 mg/L Cu (0,002-0,008 mg/L) at the MPC 0,001 mg/L. The highest concentrations of heavy and transition metals occur in iron and zinc in the water. Thus, the maximum concentration value for iron and zinc are shown on the oil-gas field "Bulla" and they are follows: 0,197 mg/L and 0,171 mg/L. In each of the investigated samples were found zinc, copper, cadmium, mercury, lead, iron and nickel.
文章介绍了2011年至2013年里海阿塞拜疆地区石油和天然气田(“oil Rocks”,“Gyarbi Absheron”,“Absheron Bankasi”和“Bulla”)的水中重金属分析结果。确定铁、锌、铜的超标允许浓度;在MPC为0.05 mg/L时,铁(0,163 ~ 0,197 mg/L);在MPC为0.01 ~ 0.05 mg/L时,锌(0,141 ~ 0,171 mg/L);在MPC为0.001 mg/L时,铜(0,002 ~ 0,008 mg/L)。水中的铁和锌中重金属和过渡金属的浓度最高。由此可见,“布拉”油气田铁、锌的最大浓化值分别为:0.197 mg/L和0.171 mg/L。在每一个被调查的样本中都发现了锌、铜、镉、汞、铅、铁和镍。
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引用次数: 0
A Concrescence between Second and Third Molars 第二磨牙和第三磨牙之间的接合
Pub Date : 2015-08-01 DOI: 10.20286/NOVA-JMBS-040253
M. Mehdizadeh, B. Saberi, S. Bayat
Background: Concrescence is a rare dental anomaly in which juxtaposed teeth are united in the cementum but not in the dentin. The incidence of Concrescence teeth is reported to be highest in the posterior maxilla. It often involves a second molar with roots in near proximity to those of a third molar. It is more common on maxillary third and second molars and may be inadvertently diagnosed during a tooth extraction. Although the exact etiology of concrescence has not yet been explained, it is usually suspected that space restriction during development, local trauma, excessive occlusal force or local infection after development play an important role. Unexpected complications arising from the concrescence may lead to legal issues. Case Report: Extracting right maxillary second molar in a 33-year-old female patient with a chief complaint of toothache in a right maxillary second molar. It became evident that the second and third molars were attached between the roots. So both teeth were extracted a traumatically and healing was uneventful. Conclusion: In fact, concrescence is not common anomaly, so the clinician should always consider it, especially in the case of maxillary molars, and the patient should be informed about its complications. A small fused area may be separated during the extraction. But a broader connected area (like in this case) may lead to the extraction of both involved teeth.
背景:牙连是一种罕见的牙齿异常,并列的牙齿在牙骨质中连在一起,而不是在牙本质中。据报道,牙齿愈合的发生率最高的是后上颌。它通常涉及第二磨牙,其根与第三磨牙的根非常接近。它在上颌第三和第二磨牙上更常见,可能在拔牙时无意中被诊断出来。虽然愈合的确切病因尚未解释,但通常怀疑发育过程中空间限制、局部创伤、咬合力过大或发育后局部感染起重要作用。由于和解而产生的意想不到的复杂情况可能导致法律问题。病例报告:拔除右侧上颌第二磨牙的33岁女性患者,主诉为右侧上颌第二磨牙疼痛。很明显,第二和第三颗磨牙连着牙根之间。所以两颗牙都是外伤拔出来的愈合过程很顺利。结论:事实上,牙愈合并不是常见的异常,临床医生应经常考虑,特别是上颌磨牙,并应告知患者其并发症。在提取过程中可能会分离出一个小的熔合区域。但是更大的连接区域(就像这个例子)可能会导致拔出两颗相关的牙齿。
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引用次数: 1
Estimation of Total Testosterone levels in Sudanese Male Smoker 苏丹男性吸烟者总睾酮水平的估计
Pub Date : 2015-08-01 DOI: 10.20286/NOVA-JMBS-040243
Al Toma H. Bajouri, M. Sabahelkhier.
The effect of smoking on testosterone levels is important given the recent interest in the link between low levels of testosterone and the development of cardiovascular disease because smoking has bad effect on diet of person i,e. Heavy smoking lead to loss appetite for person. Cigarette smoking is highly prevalent among men. Many studies have evaluated the effect of cigarette smoking on levels of male reproductive hormones; however, the findings still remain controversial. The main objective was to study the effect of cigarette smoking on total testosterone hormone in male. Eighty blood samples (80) were collected from apparently healthy Sudanese individuals. Group one (40 males) was represented smoker group, age with 18 -50 year, duration of smoking ranged from 5 – 25 years and average number of cigarette day is 17.18± 13.1. While other 40 individual are non smoker (Control), all volunteers were recruited from Khartoum city, Sudan. Four ml of venous blood were collected from each volunteer serum, Total testosterone were measured using (E L I SA) full automated hormone analyzer. The results were indicated that total testosterone levels among the smoker (M ±SD 3.6 ± 3.6) were significantly low compared with control group (M ± SD 5.2 ± 2.3). In addition, it is not effect by age and BMI (Body Mass Index), but it is effect by number of cigarette day.
吸烟对睾酮水平的影响很重要,因为最近人们对睾酮水平低与心血管疾病的发展之间的联系很感兴趣,因为吸烟对人的饮食有不良影响。大量吸烟会使人失去食欲。吸烟在男性中非常普遍。许多研究评估了吸烟对男性生殖激素水平的影响;然而,这些发现仍然存在争议。主要目的是研究吸烟对男性总睾酮激素的影响。从表面健康的苏丹人身上采集了80份血样(80份)。第1组(40名男性)为典型吸烟组,年龄18 ~ 50岁,吸烟年限5 ~ 25年,平均吸烟日数17.18±13.1支。另外40人不吸烟(对照),所有志愿人员都是从苏丹喀土穆市征聘的。采集每位志愿者血清静脉血4 ml,采用(E L I SA)全自动激素分析仪测定总睾酮水平。结果显示,吸烟者总睾酮水平(M±SD 3.6±3.6)明显低于对照组(M±SD 5.2±2.3)。此外,它不受年龄和BMI(身体质量指数)的影响,而是受吸烟数量的影响。
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引用次数: 0
WISDOM OF THE ELDERLY 老人的智慧
Pub Date : 2015-06-21 DOI: 10.12775/MBS.2015.015
K. Porzych, A. Polak-Szabela, Kajetan Hadzik
In the studies on wisdom of the elderly, there are two kinds of wisdom: pragmatic and transcendent (spiritual), which is a general respond to the world and is associated with the level of personality development. Through its specific context, old age creates conditions for achieving wisdom. The fact whether these opportunities will be used and lead to the development of human personality in old age depends on the individuals.
在老年人智慧的研究中,有两种智慧:实用智慧和超越智慧(精神智慧),这是一种对世界的一般反应,与人格发展水平有关。通过其特定的背景,老年创造了获得智慧的条件。事实上,这些机会是否会被利用,并导致人类个性的发展,在老年取决于个人。
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引用次数: 1
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