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Cold Water Immersion: Simultaneous Assessment of Cerebral Oxygenation, Vascular Function, and Thermoregulatory Responses. 冷水浸泡:同时评估脑氧合、血管功能和体温调节反应。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-17 DOI: 10.1093/milmed/usaf570
Cory M Smith, Owen F Salmon, Thomas Statz, Matt D Segovia, Cierra B Ugale, Rachel Rauth
<p><strong>Introduction: </strong>Developing a greater understanding of how the body reacts following cold water immersion (CWI) and its impact on human performance is required for the development of future monitoring technologies and countermeasures to reduce cold-induced impairments. Currently, there are no field-deployable technologies for real-time monitoring of cold-induced neurochemical and metabolic changes, limiting physiological assessment tools for monitoring the impact of cold immersion on cognitive and physical performance. Functional near-infrared spectroscopy (fNIRS) may be an effective technique for monitoring the impact of cold exposures on neurophysiological functions; however, a deeper examination of the fNIRS patterns of responses is needed to progress the interpretability of this technique in austere environments. Therefore, the purpose of this study was to examine the cerebral hemodynamic responses over the prefrontal cortex (PFC) as well as respiratory and common carotid artery (CCA) responses during a 10-minute CWI.</p><p><strong>Materials and methods: </strong>Twenty-six participants (age = 23.6 ± 4.3 years) completed 2 testing visits, which consisted of a 10-minute thermoneutral water immersion (TWI; 35 °C) or CWI (15 °C). Functional near-infrared spectroscopy-derived oxygenated hemoglobin (O2Hb) was measured over the PFC, as well as respiratory rate, tidal volume, and CCA diameter, were measured at the beginning and end of the immersion period. In addition, skin temperature (Tsk) and thermal perception were measured during each condition. Repeated measures ANOVA's were used to examine the condition and time course of response changes for Tsk, respiratory rate, tidal volume, thermal perception, and CCA diameter. A general linear model analysis was used to examine differences in beta values of the O2Hb between the TWI and CWI conditions. This study was approved by the university's institutional review board (IRB: 2115890).</p><p><strong>Results: </strong>There was no significant change in O2Hb during the TWI condition (P = .15), however, O2Hb significantly increased during the CWI (P < .01). The CCA diameter did not change during the TWI (P = .84) but increased during the CWI (P < .01). There was a significant decrease in Tsk (P < .01) during CWI and greater thermal perception compared to TWI (P < .01), which showed no significant changes (P = .06-.82). Respiratory rate remained unchanged (P = .59). Tidal volume was significantly greater during the CWI compared to TWI (P < .01).</p><p><strong>Conclusions: </strong>Initial exposure to CWI induced a cold shock response with a 43% increase in tidal volume, without a corresponding increase in respiratory rate. This suggested a potential, intuitive, cold-mitigation strategy in cold naïve participants. In addition, the O2Hb responses indicated a short-lived, cold-induced mismatch between cerebral oxygen demand and supply. The increase in cerebral oxygenation reflects a cold-indu
进一步了解人体在冷水浸泡(CWI)后的反应及其对人体表现的影响,是开发未来监测技术和减少冷致损伤的对策所必需的。目前,还没有现场可部署的技术来实时监测冷诱导的神经化学和代谢变化,这限制了监测冷浸泡对认知和身体表现影响的生理评估工具。功能近红外光谱(fNIRS)可能是监测冷暴露对神经生理功能影响的有效技术。然而,需要对近红外光谱响应模式进行更深入的研究,以提高该技术在严峻环境中的可解释性。因此,本研究的目的是检查10分钟CWI期间前额叶皮层(PFC)的脑血流动力学反应以及呼吸和颈总动脉(CCA)反应。材料和方法:26名参与者(年龄= 23.6±4.3岁)完成2次测试访问,包括10分钟的热中性水浸泡(TWI; 35°C)或CWI(15°C)。在PFC上测量功能性近红外光谱衍生的含氧血红蛋白(O2Hb),并在浸泡期开始和结束时测量呼吸速率、潮气量和CCA直径。此外,在每个条件下测量皮肤温度(Tsk)和热感觉。采用重复测量方差分析(Repeated measures ANOVA’s)检验Tsk、呼吸频率、潮气量、热感觉和CCA直径的反应变化情况和时间过程。使用一般线性模型分析来检查TWI和CWI条件下O2Hb β值的差异。该研究已获得大学机构审查委员会(IRB: 2115890)的批准。结果:在TWI条件下,O2Hb无明显变化(P =。15),然而,在CWI期间O2Hb显著增加(P结论:CWI初始暴露诱导冷休克反应,潮气量增加43%,而呼吸速率未相应增加。这表明在寒冷naïve参与者中有一种潜在的、直观的缓解寒冷的策略。此外,O2Hb反应表明脑氧需求和供应之间存在短暂的、寒冷引起的不匹配。脑氧合的增加反映了冷诱导的脑血流量增加,以防止局部温度下降,同时增加逆流血管化和代谢性热产生。
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引用次数: 0
Validation of the Wireless Automated Hearing Test System for Clinical Use in Adults. 成人临床使用无线自动听力测试系统的验证。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-15 DOI: 10.1093/milmed/usaf566
Alyssa Davidson, Benjamin Sheffield

Objective: To evaluate the validity of the Wireless Automated Hearing Test System (WAHTS) in comparison to clinically acquired unmasked air conduction thresholds.

Design: A cross-sectional study comparing WAHTS and manual audiometry thresholds, with participants at Clinic 1 completing WAHTS followed by manual audiometry, and those at Clinic 2 completed manual audiometry first, followed by WAHTS, both on the same day.

Study sample: Ninety-three thresholds from 28 participants at Clinic 1 and 112 thresholds from 24 participants at Clinic 2 were analyzed. Participants were U.S. Service Members and represented a range of ages and hearing difficulties.

Results: The mean absolute difference between repeated WAHTS measurements was 2.21 dB (SD = 2.52 dB). Correlation coefficients for WAHTS and clinical thresholds were 0.95 (R2 = 0.91) at Clinic 1 and 0.94 (R2 = 0.94) at Clinic 2. Kappa agreement within ±10 dB was 90% at Clinic 1 and 87% at Clinic 2. Bland-Altman analysis indicated a slight bias, with WAHTS thresholds averaging 2-3 dB better than clinical thresholds.

Conclusions: Wireless Automated Hearing Test System demonstrated strong agreement with clinical audiometry, supporting its use for unmasked threshold evaluations. Its portability and accuracy suggest potential for expanding access to hearing health care, particularly in remote or resource-limited environments.

目的:评价无线自动听力测试系统(WAHTS)与临床获得的无遮蔽空气传导阈值的有效性。设计:横断面研究比较WAHTS和手动听力学阈值,1号诊所的参与者先完成WAHTS,然后进行手动听力学,2号诊所的参与者先完成手动听力学,然后进行WAHTS,两者都在同一天完成。研究样本:分析了1号诊所28名参与者的93个阈值和2号诊所24名参与者的112个阈值。参与者是美国服役人员,代表了不同年龄和听力障碍。结果:重复WAHTS测量的平均绝对差为2.21 dB (SD = 2.52 dB)。临床1的WAHTS与临床阈值的相关系数为0.95 (R2 = 0.91),临床2的相关系数为0.94 (R2 = 0.94)。在±10 dB范围内Kappa一致性在临床1为90%,在临床2为87%。Bland-Altman分析显示轻微偏差,WAHTS阈值平均优于临床阈值2-3 dB。结论:无线自动听力测试系统与临床听力学表现出强烈的一致性,支持其用于无掩饰阈值评估。它的便携性和准确性表明有可能扩大获得听力保健的机会,特别是在偏远或资源有限的环境中。
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引用次数: 0
Assessing United States Military Veterans' Fertility Intentions Before and After Military Service Using a Cognitive-Social Model. 用认知-社会模型评估美国退伍军人服役前后的生育意向。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-15 DOI: 10.1093/milmed/usaf547
A M Racila, Kenda R Stewart Steffensmeier, Monica B Paez, Emily E Chasco, Anne G Sadler, Aaron T Seaman, Ginny L Ryan, Michelle A Mengeling
<p><strong>Introduction: </strong>Military service represents a unique life transition occurring during early adulthood. Limited existing work suggests that military service delays childbearing for service members compared to civilians at a similar point in the life course and that this effect is stronger for women. The Cognitive-Social Model of Fertility Intentions posits that women form clearly defined fertility intentions when encountering situations across the life course that motivate cognitive attention toward childbearing enough that women form a conscious, actionable family-building plan. We aimed to qualitatively investigate factors influencing U.S. military veterans' fertility planning before and after military service using the Cognitive-Social Model of Fertility Intentions. To our knowledge, no previous study has qualitatively investigated U.S. military veterans' fertility intentions, nor those of men generally, using this model.</p><p><strong>Materials and methods: </strong>Among participants who had previously completed computer-assisted telephone interviews as part of a national U.S. study investigating infertility and trauma experiences in this population, a total of 60 U.S. military veterans who had been diagnosed with combat-related Post-Traumatic Stress Disorder (PTSD) or who had experienced attempted or completed military sexual assault; a toxin exposure; or a combat injury including pelvic, head, or spinal cord injury were recruited by fertility status: infertile (n = 20), not infertile has biological children (n = 20), not infertile and no biological children (n = 20). We performed thematic analysis of 60 semi-structured interviews with these U.S. military veteran women and men in relation to Cognitive-Social Model of Fertility Intentions constructs. Interviews assessed socio-structural factors veterans considered important when planning their families before, during, and after military service.</p><p><strong>Results: </strong>Before military service, veterans expressed expectations of forming a future nuclear family or expressed no childbearing expectations. Several situations emerging during and after military service motivated attention to childbearing plans, including suitable partnership, fears of deployment, age benchmarks to conclude childbearing, and military trauma. Veteran women and men reported similar fertility-relevant factors motivating attention to childbearing unique to military service, including service-related demands and military trauma.</p><p><strong>Conclusions: </strong>Our qualitative findings can help support Veterans Health Administration (VHA)'s efforts to anticipate reproductive healthcare services needed for both men and women. A better understanding of the contextual factors impacting post-military fertility intentions can support VHA's Whole Health approach-understanding what matters to the person, not what's the matter with the person-and potentially improve clinician-veteran communication and
简介:服兵役代表了一种发生在成年早期的独特的人生转变。有限的现有研究表明,与平民相比,在生命历程的类似阶段,服兵役会推迟服役人员的生育时间,而且这种影响对女性更强烈。生育意向的认知-社会模型假设,当女性在生命历程中遇到足以激发对生育的认知关注的情况时,就会形成明确的生育意向,从而形成有意识的、可操作的家庭建设计划。本研究旨在利用生育意向的认知-社会模型,对美国退伍军人服兵役前后生育计划的影响因素进行定性研究。据我们所知,以前没有研究定性调查过美国退伍军人的生育意愿,也没有研究使用这个模型来调查男性的生育意愿。材料和方法:在之前完成计算机辅助电话访谈的参与者中,有60名美国退伍军人被诊断患有与战斗有关的创伤后应激障碍(PTSD)或经历过未遂或已完成的军事性侵犯;毒素暴露;或战斗损伤,包括骨盆,头部或脊髓损伤,按生育状况招募:不育(n = 20),非不育有亲生子女(n = 20),非不育无亲生子女(n = 20)。我们对60位美国退伍军人的半结构化访谈进行了主题分析,这些访谈与生育意向的认知-社会模型结构有关。访谈评估了退伍军人在服兵役之前、期间和之后计划家庭时认为重要的社会结构因素。结果:在服兵役前,退伍军人表达了对未来组建核心家庭的期望或没有生育期望。在服兵役期间和之后出现的一些情况促使人们关注生育计划,包括合适的伴侣关系、对部署的恐惧、结束生育的年龄基准和军事创伤。退伍军人男女报告了类似的生育相关因素,这些因素促使人们注意到兵役特有的生育问题,包括与服务有关的需求和军事创伤。结论:我们的定性研究结果可以帮助退伍军人健康管理局(VHA)预测男性和女性所需的生殖保健服务。更好地了解影响退伍后生育意愿的环境因素可以支持VHA的“整体健康”方法——了解对人重要的是什么,而不是个人的问题——并有可能改善临床医生与退伍军人的沟通,并为生殖保健政策的制定提供信息。
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引用次数: 0
Expanding the Use of Whole Blood on the Battlefield-New JTS CPG on Type A Whole Blood. 扩大全血在战场上的应用——新JTS全血CPG。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-15 DOI: 10.1093/milmed/usaf569
Jennifer Gurney, Jan-Michael Van Gent, Remealle How, Matthew D Tadlock

The Joint Trauma System and Armed Services Blood Program have collaborated to develop a Clinical Practice Guideline for the use of Type A Whole Blood to expand the availability of whole blood in the operational environment. This MPO Minute discusses the rationale, key considerations, and recommendations outlined in the CPG.

联合创伤系统和武装部队血液项目合作制定了a型全血使用的临床实践指南,以扩大全血在作战环境中的可用性。本MPO纪要讨论CPG中概述的基本原理、关键考虑因素和建议。
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引用次数: 0
Highlighting the Critical Need for Informaticists in the Military Health System. 强调军事卫生系统对信息学家的迫切需求。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-14 DOI: 10.1093/milmed/usaf558
Matthew Kilboy, Kristine Garrison, Stacy Stats, John de Geus, Nguyet Allbaugh, Matthew Barnes, Julia Olson, Jason Walker

As healthcare systems evolve to integrate digital technologies, the Military Health System (MHS) faces unique challenges requiring specialized expertise in health informatics. Health informatics enables the optimization of workflows, enhances patient safety, and supports operational readiness by transforming data into actionable insights. This manuscript discusses the critical role informaticists play in supporting the mission of the MHS by improving clinical outcomes, facilitating health data interoperability, and advancing medical research. Despite their pivotal role, the informatics workforce across the military services is inconsistently tracked, leading to significant gaps in resource allocation and strategic planning. Quantitative estimates suggest that while the Navy and Air Force have recognized informaticists through specific qualification designators and special experience identifiers, formal designation and dedicated billets remain limited, particularly in the Army. Barriers such as budget constraints, reliance on collateral duties, and lack of unified policy frameworks impede progress. To address these challenges, this article recommends establishing formal informatics subspecialties, developing standardized education pathways, and designating specific billets across the Services. It also proposes a vision where informaticists are embedded throughout the MHS, enabling predictive health models, interoperability with Veterans Affairs systems, and real-time decision support in deployed environments. Investing in a robust informatics workforce is not merely a technological enhancement but a strategic imperative essential for maintaining force health, medical readiness, and national security.

随着医疗保健系统发展到集成数字技术,军事卫生系统(MHS)面临着独特的挑战,需要健康信息学方面的专业知识。健康信息学可以优化工作流程,提高患者安全性,并通过将数据转换为可操作的见解来支持运营准备。本文讨论了信息学家通过改善临床结果、促进健康数据互操作性和推进医学研究,在支持MHS使命方面发挥的关键作用。尽管各军种的信息学人员发挥着关键作用,但他们的跟踪不一致,导致资源分配和战略规划方面存在重大差距。定量估计表明,虽然海军和空军已经通过特定的资格标识和特殊经验标识来认可信息学家,但正式的标识和专用的职位仍然有限,特别是在陆军。预算限制、对附带责任的依赖以及缺乏统一的政策框架等障碍阻碍了进展。为了应对这些挑战,本文建议建立正式的信息学子专业,开发标准化的教育途径,并在各个服务中指定特定的职位。它还提出了一个愿景,即信息学家嵌入整个MHS,实现预测健康模型,与退伍军人事务系统的互操作性,以及部署环境中的实时决策支持。投资于一支强大的信息学队伍不仅是技术上的提高,而且是维持部队健康、医疗准备和国家安全所必需的战略要求。
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引用次数: 0
Neuromuscular Performance Changes in Response to the Australian Special Forces Selection Course. 澳大利亚特种部队选拔课程对神经肌肉性能的影响。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-13 DOI: 10.1093/milmed/usaf541
Angela Uphill, Kristina L Kendall, Stuart Guppy, Michael Vacher, Simon Parker, Hannah Brown, Brendan Ashmore, Travis Zomer, G Gregory Haff
<p><strong>Introduction: </strong>Strenuous military activities, such as Special Forces (SF) selection courses, are known to involve high physical loads in the presence of food and sleep deprivation, which can have detrimental impacts on physical performance. Understanding the magnitude of performance deficit and the time required for recovery associated with these events, is important for injury prevention and maintaining operational readiness. The purpose of this study was to investigate the changes in physical performance in response to the Australian SF Selection Course (SF-SC) and to monitor recovery throughout 8 weeks following the course.</p><p><strong>Materials and methods: </strong>Ninety-three healthy male participants (age: 28 ± 4 years) were recruited; follow-up data were available from those who successfully completed the SF-SC (n = 21). The isometric mid-thigh pull (IMTP), countermovement jump (CMJ), serum hormone concentrations (total testosterone, free testosterone, cortisol, sex hormone binding globulin [SHBG], testosterone:cortisol ratio [T:C]), and body composition (body mass, lean mass) were assessed before the course, immediately post-course, and at 1, 3, 5, and 8 weeks post-course. This study employed Wilcoxon rank tests for pairwise comparisons between baseline and immediate post-course measures, as well as baseline measures with subsequent time points (weeks 1, 3, 5, and 8) to assess recovery time. Additionally, linear mixed effects models (LMEs) were used to analyze the effects of body composition and hormones on physical performance.</p><p><strong>Results: </strong>IMTP peak force was reduced by 16 ± 11% (P < .01, ES = 0.83, 95% CI [0.66-0.88]), and peak force relative to lean mass was reduced by 13 ± 13% (P < .05, ES = 0.76, 95% CI [0.54-0.88]) in response to the SF-SC. No other measured IMTP variable demonstrated statistically significant change in response to the SF-SC, and all measured IMTP variables had returned to baseline levels at 1 week post-course. Jump height was reduced by 28 ± 9% (P < .001, ES = 0.88, 95% CI [0.88-0.88]) in response to the SF-SC. CMJ peak power and mean power were reduced by 30 ± 5.6% (P < .001, ES = 0.88, 95% CI [0.88-0.88]), and 29 ± 7.5% (P < .001, ES = 0.88, 95% CI [0.88-0.88]), respectively. Concentric peak force was reduced by 26 ± 10% (P < .001, ES = 0.88, 95% CI [0.88-0.88]), breaking peak force by 28 ± 26.3% (P < .01, ES = 0.86, 95% CI [0.76-0.88], and flight time:contraction time (F:T) by 26 ± 10.8% (P < .001, ES = 0.88, 95% CI [0.88-0.88]). CMJ variables took between 1 and 3 weeks to recover to baseline. LMEs demonstrated that total testosterone, free testosterone, and the T:C ratio all had a significant effect on CMJ jump height and peak power and IMTP peak force and peak rate of force development (RFD). Body mass and lean mass exhibited significant positive effects on peak power and peak force, while they did not influence jump height or peak RFD.</p><p><strong>Conclusions: </st
简介:艰苦的军事活动,如特种部队(SF)选拔课程,在食物和睡眠被剥夺的情况下涉及高体力负荷,这可能对身体表现产生有害影响。了解与这些事件相关的性能缺陷的程度和恢复所需的时间,对于预防伤害和保持作战准备非常重要。本研究的目的是调查澳大利亚SF选拔课程(SF- sc)后身体表现的变化,并监测课程后8周内的恢复情况。材料与方法:招募健康男性93例(年龄28±4岁);随访数据来自成功完成SF-SC的患者(n = 21)。在疗程开始前、疗程结束后以及疗程结束后1周、3周、5周和8周评估等距大腿中部牵拉(IMTP)、反动作跳跃(CMJ)、血清激素浓度(总睾酮、游离睾酮、皮质醇、性激素结合球蛋白[SHBG]、睾酮:皮质醇比[T:C])和身体组成(体重、瘦体重)。本研究采用Wilcoxon秩检验两两比较基线和疗程后测量值,以及基线测量值与随后时间点(第1、3、5和8周)来评估恢复时间。此外,采用线性混合效应模型(LMEs)分析了体成分和激素对运动性能的影响。结果:IMTP峰值力降低了16±11% (P < 0.01, ES = 0.83, 95% CI[0.66-0.88]),相对于瘦质量的峰值力降低了13±13% (P结论:SF-SC导致强度和功率大幅下降,需要3周才能完全恢复。本研究结果可为高强度军事训练后的训练及康复干预提供参考。
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引用次数: 0
Prevalence & Characteristics of E-Cigarette and Nicotine Pouch Use Among United States Military Veteran Smokers. 美国退伍军人吸烟者中电子烟和尼古丁袋使用的患病率和特征。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-13 DOI: 10.1093/milmed/usaf521
Noah R Wolkowicz, Elizabeth K C Schwartz, Kathryn R Hefner, Mehmet Sofuoglu
<p><strong>Introduction: </strong>The recent growth of Alternative Nicotine Products (ANP), such as e-cigarettes and Nicotine Pouches (NPs), raises concerns for groups with heightened health-risks from tobacco/nicotine products, like U.S. military veterans. Considering, and given the limited available data on veteran ANP use, we explored the prevalence, perceptions, and use characteristics of two ANP types (e-cigarettes and NPs) in this population.</p><p><strong>Materials and methods: </strong>In the context of a larger, ongoing study examining veteran beliefs, awareness, and use of nicotine products, we conducted an anonymous, cross-sectional, paper-and-pencil survey examining ANP use/perceptions at a large Veterans Health Administration (VHA) hospital in the northeast U.S. Veterans self-describing as current smokers (i.e., responding affirmatively to research assistant inquiry of "are you a current smoker?") were provided a 42 closed-ended item survey inquiring about demographic, psychiatric, and medical information, as well as use habits and motivations for use of cigarettes and ANPs. Veteran data was stratified into "cigarette only" vs. "dual users" (cigarettes and ANP), as well as sub-stratified by ANP type (e-cigarette vs. NP). Frequencies were tabulated per group and ANP product type. χ2/Fisher's Exact tests were used to explore potential differences between "cigarette only" and "dual users".</p><p><strong>Results: </strong>Of 100 veterans who initiated surveys, seven did not return surveys to researchers. Thus, our analytic sample consisted of N = 93 veterans who were primarily male (n = 83/93; 89.25%), >50 years old (n = 62/93; 66.67%), and Non-Hispanic and White (n = 38/93; 40.86%) or Black/African US (n = 31/93; 33.33%). Roughly half of participants reported only past-month cigarette use (n = 52/93, 52.91%) or dual cigarette and ANP use (n = 41/93; 44.09%). No significant differences in rates of mental health/substance use disorders were identified between cigarette vs. cigarette + ANP user groups, χ2(3) = 0.87, P = .833. Compared to those smoking cigarettes only in the past month, dual users had a smaller proportion reporting past-year quit attempts, χ2(1)=4.59, P = .032, and more frequently reported smoking 0.5 packs-per-day (versus greater/less than 0.5 packs-per-day), χ2(2)=6.94, P = .031. Among ANP users, past-month use of both NPs and e-cigarettes was most common (n = 21/41; 51.22%), followed by e-cigarette use only (n = 17/41; 41.46%), and NP use only (n = 3/41; 7.32%). ANPs were generally described to be as addictive as combustible cigarettes (NP users: n = 13/24, 54.17%; E-cigarette users: n = 32/38, 84.21%). Across ANP products, motivations for use emphasized saving money (NP users: n = 8/24, 33.33%; e-cigarette users: n = 6/38, 15.79%) and convenience when cigarettes cannot be used (NP users: n = 6/24, 25.00%; e-cigarette users: n = 6/38, 15.79%). Compared to combustible cigarettes, NP users more frequently endorsed percepti
导语:最近尼古丁替代品(ANP)的增长,如电子烟和尼古丁袋(NPs),引起了对烟草/尼古丁产品健康风险较高的群体的关注,如美国退伍军人。考虑到退伍军人使用ANP的可用数据有限,我们探索了这一人群中两种ANP类型(电子烟和NPs)的流行程度、认知和使用特征。材料和方法:在一个更大的、正在进行的关于退伍军人信念、意识和尼古丁产品使用的研究的背景下,我们在美国东北部一家大型退伍军人健康管理局(VHA)医院进行了一项匿名、横断面、纸笔调查,调查了ANP的使用/认知,这些退伍军人自称是目前的吸烟者(即,对研究助理询问“你现在是吸烟者吗?”的问题做出肯定的回答)。提供了42个封闭式项目调查,询问人口统计、精神病学和医学信息,以及使用香烟和anp的习惯和动机。老兵数据被分成“只吸烟”和“只吸烟”两组。“双重用户”(香烟和ANP),以及按ANP类型细分的用户(电子烟与NP)。频率按组和ANP产品类型制成表格。χ2/Fisher精确检验用于探索“只吸烟”和“双吸烟者”之间的潜在差异。结果:在发起调查的100名退伍军人中,有7人没有将调查问卷返还给研究人员。因此,我们的分析样本包括N = 93名退伍军人,主要是男性(N = 83/93; 89.25%), 50岁以下(N = 62/93; 66.67%),非西班牙裔和白人(N = 38/93; 40.86%)或黑人/非洲裔美国人(N = 31/93; 33.33%)。大约一半的参与者报告仅在过去一个月吸烟(n = 52/93, 52.91%)或双重吸烟和ANP使用(n = 41/93, 44.09%)。吸烟组与吸烟+ ANP使用组的精神健康/物质使用障碍发生率无显著差异,χ2(3) = 0.87, P = .833。与过去一个月只吸烟的人相比,双吸烟者报告过去一年内戒烟的比例较小,χ2(1)=4.59, P = 0.032;报告每天吸烟0.5包(大于/小于0.5包)的频率更高,χ2(2)=6.94, P = 0.031。在ANP使用者中,过去一个月同时使用NPs和电子烟最为常见(n = 21/41; 51.22%),其次是只使用电子烟(n = 17/41; 41.46%)和只使用NP (n = 3/41; 7.32%)。anp的成瘾性与可燃香烟相当(NP使用者:n = 13/24, 54.17%;电子烟使用者:n = 32/38, 84.21%)。在ANP产品中,使用动机强调省钱(NP用户:n = 8/24, 33.33%;电子烟用户:n = 6/38, 15.79%)和在不能使用香烟时方便(NP用户:n = 6/24, 25.00%;电子烟用户:n = 6/38, 15.79%)。与可燃卷烟相比,NP用户更频繁地认为电子烟对他们的健康更有益(n = 5/24; 20.83%),尽管电子烟用户强调减少对他人的伤害或为他人树立更好的榜样(n = 5/38;每个原因的13.16%)。结论:我们的研究结果表明,在美国退伍军人中,ANP的使用水平很高,他们也描述ANP产品和可燃香烟一样容易上瘾。结果还表明,方便和成本是ANP使用的主要动机。需要进行更大规模的流行病学和实验调查,以核实目前的估计,并评估退伍军人使用香烟和麻醉药之间的影响模式。
{"title":"Prevalence & Characteristics of E-Cigarette and Nicotine Pouch Use Among United States Military Veteran Smokers.","authors":"Noah R Wolkowicz, Elizabeth K C Schwartz, Kathryn R Hefner, Mehmet Sofuoglu","doi":"10.1093/milmed/usaf521","DOIUrl":"https://doi.org/10.1093/milmed/usaf521","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The recent growth of Alternative Nicotine Products (ANP), such as e-cigarettes and Nicotine Pouches (NPs), raises concerns for groups with heightened health-risks from tobacco/nicotine products, like U.S. military veterans. Considering, and given the limited available data on veteran ANP use, we explored the prevalence, perceptions, and use characteristics of two ANP types (e-cigarettes and NPs) in this population.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;In the context of a larger, ongoing study examining veteran beliefs, awareness, and use of nicotine products, we conducted an anonymous, cross-sectional, paper-and-pencil survey examining ANP use/perceptions at a large Veterans Health Administration (VHA) hospital in the northeast U.S. Veterans self-describing as current smokers (i.e., responding affirmatively to research assistant inquiry of \"are you a current smoker?\") were provided a 42 closed-ended item survey inquiring about demographic, psychiatric, and medical information, as well as use habits and motivations for use of cigarettes and ANPs. Veteran data was stratified into \"cigarette only\" vs. \"dual users\" (cigarettes and ANP), as well as sub-stratified by ANP type (e-cigarette vs. NP). Frequencies were tabulated per group and ANP product type. χ2/Fisher's Exact tests were used to explore potential differences between \"cigarette only\" and \"dual users\".&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Of 100 veterans who initiated surveys, seven did not return surveys to researchers. Thus, our analytic sample consisted of N = 93 veterans who were primarily male (n = 83/93; 89.25%), &gt;50 years old (n = 62/93; 66.67%), and Non-Hispanic and White (n = 38/93; 40.86%) or Black/African US (n = 31/93; 33.33%). Roughly half of participants reported only past-month cigarette use (n = 52/93, 52.91%) or dual cigarette and ANP use (n = 41/93; 44.09%). No significant differences in rates of mental health/substance use disorders were identified between cigarette vs. cigarette + ANP user groups, χ2(3) = 0.87, P = .833. Compared to those smoking cigarettes only in the past month, dual users had a smaller proportion reporting past-year quit attempts, χ2(1)=4.59, P = .032, and more frequently reported smoking 0.5 packs-per-day (versus greater/less than 0.5 packs-per-day), χ2(2)=6.94, P = .031. Among ANP users, past-month use of both NPs and e-cigarettes was most common (n = 21/41; 51.22%), followed by e-cigarette use only (n = 17/41; 41.46%), and NP use only (n = 3/41; 7.32%). ANPs were generally described to be as addictive as combustible cigarettes (NP users: n = 13/24, 54.17%; E-cigarette users: n = 32/38, 84.21%). Across ANP products, motivations for use emphasized saving money (NP users: n = 8/24, 33.33%; e-cigarette users: n = 6/38, 15.79%) and convenience when cigarettes cannot be used (NP users: n = 6/24, 25.00%; e-cigarette users: n = 6/38, 15.79%). Compared to combustible cigarettes, NP users more frequently endorsed percepti","PeriodicalId":18638,"journal":{"name":"Military Medicine","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145513390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Fabrication of Requisite, Durable, Printed Upper Extremity Orthoses Through Innovative Means in an Austere Environment. 通过创新的方法在严峻的环境中制造必要的,耐用的,印刷的上肢矫形器。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-13 DOI: 10.1093/milmed/usaf539
Manuela Gaviria, Simon B Gott, Andrew W Ellis, William P Seigfreid, Adam J Wallum, Braden N Miller, Wensheng Zhang, Casey M Sabbag

Introduction: In deployed military settings, ensuring consistent access to durable medical equipment (DME) remains a significant challenge due to logistical and supply chain limitations. This study retrospectively reviews the clinical use of 3D-printed upper extremity orthoses fabricated out of necessity at Al Udeid Air Base (AUAB), Qatar, in response to such shortages. Devices were implemented during routine care and assessed through provider documentation and photographic evidence. Although representative of logistics-supported Role 2s, the results may not fully extend to forward combat Role 2s without adaptations.

Materials and methods: A retrospective chart review was conducted for patients treated with 3D-printed orthotic splints between March and July 2024 at AUAB. Printers included a FormLabs 3B+ SLA and Creality CR-6 MAX FDM device, using Formlabs Draft V2 resin and Overture PLA filament. Devices were fabricated using an open-source design to meet immediate clinical needs, with print times of 1-2 h per splint. Variables extracted included splint type, application site, patient tolerance, and clinical utility as documented in the medical record.

Results: Multiple splint designs were fabricated, including an en bloc thumb spica, a heat-moldable flat PLA splint, and a series of DIP extension splints for mallet finger injuries. The en bloc splint, printed using SLA resin, provided satisfactory fit and comfort with a stockinette liner and adjustable securing mechanisms (Figure 1). A flat PLA-based splint was customized at bedside through heat molding (Figure 2 and 3). Finger extension splints were printed in batch-scaled sizes and used for 8-week immobilization in 1 patient with a soft tissue mallet deformity (Figure 4). All splints were well tolerated, functionally effective, and enabled continuity of duty with minimal limitation. Compared to plaster, 3D prints offered better ventilation and durability.

Conclusions: 3D printing enabled the timely fabrication of upper extremity orthoses during a period of equipment shortage at a deployed military medical facility. These devices were created to fulfill immediate clinical needs and were retrospectively evaluated using documentation from routine patient care. This study highlights the real-world feasibility of using 3D printing in constrained settings to deliver personalized orthopedic support when conventional DME is unavailable. Printers are moderately robust but sensitive to dust, temperature, and motion; ruggedized models and IP-compliant designs are recommended for austere use. Costs may exceed traditional initially but offer logistics savings. Multi-specialty applications justify deployment. Although limited by its retrospective design and absence of formal outcome tracking, the findings demonstrate the potential for 3D printing to reduce supply chain dependence, support operational autonomy, and enhanc

导论:在部署的军事环境中,由于后勤和供应链的限制,确保持续获得耐用医疗设备(DME)仍然是一项重大挑战。本研究回顾性回顾了3d打印上肢矫形器在卡塔尔Al Udeid空军基地(AUAB)的临床应用,以应对此类短缺。设备在日常护理中实施,并通过提供者文件和照片证据进行评估。虽然具有后勤支持角色2s的代表性,但如果没有调整,结果可能无法完全扩展到前方战斗角色2s。材料与方法:对2024年3月至7月在AUAB接受3d打印矫形夹板治疗的患者进行回顾性图表分析。打印机包括FormLabs 3B+ SLA和Creality CR-6 MAX FDM设备,使用FormLabs Draft V2树脂和Overture PLA长丝。设备采用开源设计制造,以满足即时临床需求,每个夹板的打印时间为1-2小时。提取的变量包括夹板类型、应用部位、患者耐受性和病历中记录的临床效用。结果:制作了多种夹板设计,包括拇指整体夹板,热成型扁平PLA夹板和一系列用于锤状指损伤的DIP扩展夹板。整体夹板,使用SLA树脂印刷,提供了令人满意的合身和舒适的袜子衬垫和可调节的固定机制(图1)。通过热成型在床边定制平面pla基夹板(图2和3)。手指伸展夹板批量打印,用于1例软组织槌状畸形患者8周的固定(图4)。所有的夹板耐受性良好,功能有效,并能以最小的限制保持工作的连续性。与石膏相比,3D打印提供了更好的通风和耐用性。结论:在部署的军事医疗设施设备短缺期间,3D打印使上肢矫形器能够及时制造。这些装置是为了满足即时的临床需求而设计的,并根据常规患者护理的文件进行回顾性评估。这项研究强调了在现实世界中,当传统的DME无法使用时,在受限的环境中使用3D打印来提供个性化骨科支持的可行性。打印机强度适中,但对灰尘、温度和运动很敏感;坚固耐用的型号和ip兼容的设计,建议严格使用。最初的成本可能会超过传统,但可以节省物流成本。多专业应用证明了部署的合理性。尽管受限于其回顾性设计和缺乏正式的结果跟踪,但研究结果表明,3D打印在减少供应链依赖、支持操作自主权和增强部署环境中的护理服务方面具有潜力。未来的研究应评估3d打印矫形器的长期耐用性、患者结果和成本效益,并探索在其他形式的现场就绪医疗设备上的扩展应用,以提高军事和人道主义环境下的战备状态。
{"title":"The Fabrication of Requisite, Durable, Printed Upper Extremity Orthoses Through Innovative Means in an Austere Environment.","authors":"Manuela Gaviria, Simon B Gott, Andrew W Ellis, William P Seigfreid, Adam J Wallum, Braden N Miller, Wensheng Zhang, Casey M Sabbag","doi":"10.1093/milmed/usaf539","DOIUrl":"https://doi.org/10.1093/milmed/usaf539","url":null,"abstract":"<p><strong>Introduction: </strong>In deployed military settings, ensuring consistent access to durable medical equipment (DME) remains a significant challenge due to logistical and supply chain limitations. This study retrospectively reviews the clinical use of 3D-printed upper extremity orthoses fabricated out of necessity at Al Udeid Air Base (AUAB), Qatar, in response to such shortages. Devices were implemented during routine care and assessed through provider documentation and photographic evidence. Although representative of logistics-supported Role 2s, the results may not fully extend to forward combat Role 2s without adaptations.</p><p><strong>Materials and methods: </strong>A retrospective chart review was conducted for patients treated with 3D-printed orthotic splints between March and July 2024 at AUAB. Printers included a FormLabs 3B+ SLA and Creality CR-6 MAX FDM device, using Formlabs Draft V2 resin and Overture PLA filament. Devices were fabricated using an open-source design to meet immediate clinical needs, with print times of 1-2 h per splint. Variables extracted included splint type, application site, patient tolerance, and clinical utility as documented in the medical record.</p><p><strong>Results: </strong>Multiple splint designs were fabricated, including an en bloc thumb spica, a heat-moldable flat PLA splint, and a series of DIP extension splints for mallet finger injuries. The en bloc splint, printed using SLA resin, provided satisfactory fit and comfort with a stockinette liner and adjustable securing mechanisms (Figure 1). A flat PLA-based splint was customized at bedside through heat molding (Figure 2 and 3). Finger extension splints were printed in batch-scaled sizes and used for 8-week immobilization in 1 patient with a soft tissue mallet deformity (Figure 4). All splints were well tolerated, functionally effective, and enabled continuity of duty with minimal limitation. Compared to plaster, 3D prints offered better ventilation and durability.</p><p><strong>Conclusions: </strong>3D printing enabled the timely fabrication of upper extremity orthoses during a period of equipment shortage at a deployed military medical facility. These devices were created to fulfill immediate clinical needs and were retrospectively evaluated using documentation from routine patient care. This study highlights the real-world feasibility of using 3D printing in constrained settings to deliver personalized orthopedic support when conventional DME is unavailable. Printers are moderately robust but sensitive to dust, temperature, and motion; ruggedized models and IP-compliant designs are recommended for austere use. Costs may exceed traditional initially but offer logistics savings. Multi-specialty applications justify deployment. Although limited by its retrospective design and absence of formal outcome tracking, the findings demonstrate the potential for 3D printing to reduce supply chain dependence, support operational autonomy, and enhanc","PeriodicalId":18638,"journal":{"name":"Military Medicine","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145513454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucose Homeostasis Remains Normal in a Physically Active Military Population. 在积极运动的军人群体中,葡萄糖稳态保持正常。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-13 DOI: 10.1093/milmed/usaf512
Adam W Potter, Juliette I Jacques, Christopher L Chapman, William J Tharion, David P Looney, Karl E Friedl

Introduction: Glucose dysregulation is a significant obesity-related comorbidity known to impair both mental and physical performance. Glycated hemoglobin (HbA1c), a measure of average glucose regulation over 2-3 months, is elevated in over a third of American adults, indicating prediabetes (5.7-6.4%) or type 2 diabetes mellitus (≥ 6.5%). However, the 'fit-fat' concept suggests that physical activity may mitigate the adverse effects of adiposity on metabolic health.

Materials and methods: This study investigated the relationship between relative body fat (%BF), HbA1c, and maximal oxygen uptake (V.O2max) as a surrogate measure of physical activity, in 216 physically active military personnel (188 men, 28 women).

Results: In men, fat mass (FM) was significantly, but weakly, inversely associated with HbA1c (β = -0.008, 95% CI [-0.015 to 0.000], SE = 0.004, P = 0.048), a finding that warrants further investigation. Maximal oxygen uptake was not significantly associated with HbA1c in either men or women. The variance explained by these models was low. Cluster analysis identified 3 distinct clusters with differing profiles of adiposity and fitness, but no significant differences in HbA1c were observed between them (F(2, 213) = 0.72, P = 0.488).

Conclusions: In this physically active military population, normal mean HbA1c levels (5.2%) suggest that regular physical activity may mitigate the adverse effects of adiposity on glucose homeostasis. These findings support the 'fit-fat' concept and suggest that current fitness standards may be sufficient to maintain metabolic health. Therefore, inclusion of HbA1c testing in annual physical readiness standards may not be warranted in young, physically active service members.

简介:葡萄糖失调是一种与肥胖相关的重要合并症,已知会损害精神和身体表现。糖化血红蛋白(HbA1c)是衡量2-3个月平均血糖调节的指标,在超过三分之一的美国成年人中升高,表明患有糖尿病前期(5.7-6.4%)或2型糖尿病(≥6.5%)。然而,“健康脂肪”的概念表明,体育活动可以减轻肥胖对代谢健康的不利影响。材料和方法:本研究调查了216名体力活动军人(188名男性,28名女性)的相对体脂(%BF)、糖化血红蛋白(HbA1c)和最大摄氧量(V.O2max)作为体力活动的替代指标之间的关系。结果:在男性中,脂肪量(FM)与HbA1c呈显著但微弱的负相关(β = -0.008, 95% CI[-0.015至0.000],SE = 0.004, P = 0.048),这一发现值得进一步研究。无论男女,最大摄氧量与HbA1c均无显著相关性。这些模型解释的方差很低。聚类分析确定了3个不同的肥胖和健康概况的不同集群,但HbA1c在它们之间没有显著差异(F(2,213) = 0.72, P = 0.488)。结论:在这些身体活跃的军人人群中,正常的平均HbA1c水平(5.2%)表明,有规律的身体活动可以减轻肥胖对葡萄糖稳态的不利影响。这些发现支持了“健康脂肪”的概念,并表明目前的健康标准可能足以维持代谢健康。因此,在年轻的现役军人中,将HbA1c检测纳入年度体能准备标准可能是不合理的。
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引用次数: 0
Epidemiology and Outcomes of Battlefield-Related Penetrating and Closed Traumatic Brain Injuries Compared to Non-Head Injuries: A Retrospective Cohort Study. 与非头部损伤相比,战场相关的穿透性和闭合性创伤性脑损伤的流行病学和结果:一项回顾性队列研究。
IF 1.1 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-12 DOI: 10.1093/milmed/usaf546
Melissa R Meister, Jason H Boulter, Callum D Dewar, Caren Stuebe, Erica Sercy, M Leigh Carson, Faraz Shaikh, Joseph M Yabes, Laveta Stewart, David R Tribble, Viktor Bartanusz, Bradley Dengler

Introduction: Traumatic brain injuries (TBIs) are associated with substantial morbidity and mortality. We examined characteristics and outcomes among military personnel with battlefield-related penetrating TBI (pTBI) compared to closed TBI (cTBI) and non-head injuries (without cranial injuries).

Materials and methods: Military personnel admitted to participating U.S. military hospitals (2009-2014) were classified based on injury patterns: pTBI, cTBI (head Abbreviated Injury Scale [AIS] ≥3), and non-head (≥1 non-head injury AIS ≥3). Propensity score and inverse probability of treatment weighting (IPTW) were used to assess associations with mortality, hospital stay, and infection burden.

Results: The study population included 106 pTBI patients, 259 cTBI patients, and 715 patients with non-head injuries. Patients with pTBIs were more severely injured with differing injury mechanisms compared to the other 2 groups. Patients with pTBIs had more critical care requirements versus both cTBI and non-head injury patients (P < .05) and longer hospitalization (median 27 days vs. 22; P = .041) compared to cTBI patients. More central nervous system (CNS) infections were diagnosed among patients with pTBIs (11.3%) versus cTBIs (1.2%) and non-head injuries (0.7%; P < .001). Although the overall proportion of patients who developed non-CNS infections was not significantly different between the TBI groups, there was a higher proportion among pTBI versus non-head injury patients (53.8% vs. 40.8%; P = .012). Patients with pTBIs also had less skin and soft-tissue infections and more pneumonia compared to non-head injury patients (P < .05). There was no significant difference in the proportion of mortality between the pTBI and cTBI patients (7.6% vs. 3.1%); however, it was higher compared to patients with non-head injuries (1.0%; P < .001). Sustaining any TBI (penetrating or closed) was associated with greater risk of mortality compared to non-head injuries (risk ratio: 3.71; 95% CI, 1.83-7.55).

Conclusions: Patients with pTBIs are critically injured with substantial critical care requirements and morbidity. Between patients with pTBIs and cTBIs, there was not a significant difference in non-CNS infection burden or mortality, but pTBI patients did have longer hospitalization. When compared to severely injured military personnel with non-head injuries using propensity scores and IPTW analysis, sustaining a TBI (penetrating or closed) was not associated with having more non-CNS infections or a longer hospital stay. This may be a result of the high injury severity (median of 26) and relative occurrence of polytrauma in the total population. Patients with TBIs (penetrating or closed) did have a greater risk of mortality compared to patients with non-head injuries.

外伤性脑损伤(tbi)具有很高的发病率和死亡率。我们研究了与战场相关的穿透性脑损伤(pTBI)、闭合性脑损伤(cTBI)和非头部损伤(无颅脑损伤)相比的军事人员的特征和结果。材料与方法:将2009-2014年在美军参与医院住院的军事人员按损伤类型进行分类:pTBI、cTBI(头部简略损伤量表[AIS]≥3)和非头部(≥1,非头部损伤AIS≥3)。使用倾向评分和治疗加权逆概率(IPTW)来评估与死亡率、住院时间和感染负担的关系。结果:研究人群包括106例pTBI患者,259例cTBI患者和715例非头部损伤患者。与其他两组相比,pTBIs患者损伤更严重,损伤机制不同。与cTBI和非头部损伤患者相比,ptbi患者有更多的重症监护要求(P结论:ptbi患者是严重损伤,有大量的重症监护要求和发病率。在pTBI患者和ctbi患者之间,非中枢神经系统感染负担和死亡率没有显著差异,但pTBI患者的住院时间确实更长。当使用倾向评分和IPTW分析与严重受伤的非头部损伤的军事人员进行比较时,持续的TBI(穿透性或闭合性)与更多的非中枢神经系统感染或更长的住院时间无关。这可能是由于高损伤严重程度(中位数为26)和总体人群中多发伤的相对发生率。脑损伤患者(穿透性或闭合性)与非头部损伤患者相比确实有更大的死亡风险。
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Military Medicine
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