Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02337-6
Recent patents relating to compositions, methods and systems for single-cell analysis.
有关单细胞分析的组合物、方法和系统的最新专利。
{"title":"Single-cell analysis","authors":"","doi":"10.1038/s41587-024-02337-6","DOIUrl":"10.1038/s41587-024-02337-6","url":null,"abstract":"Recent patents relating to compositions, methods and systems for single-cell analysis.","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1181-1181"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02367-0
{"title":"World’s first tax on cows","authors":"","doi":"10.1038/s41587-024-02367-0","DOIUrl":"10.1038/s41587-024-02367-0","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1161-1161"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41587-024-02367-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02355-4
Cormac Sheridan
Companies are targeting poison exons embedded in mRNA transcripts as a strategy to restore wild-type protein abundance and cell fitness in severe pediatric epilepsy and other genetic diseases.
{"title":"A new class of mRNA drugs targets poison exons","authors":"Cormac Sheridan","doi":"10.1038/s41587-024-02355-4","DOIUrl":"10.1038/s41587-024-02355-4","url":null,"abstract":"Companies are targeting poison exons embedded in mRNA transcripts as a strategy to restore wild-type protein abundance and cell fitness in severe pediatric epilepsy and other genetic diseases.","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1159-1161"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02352-7
Recent moves of note in and around the biotech and pharma industries.
近期生物技术和制药行业及其周边值得关注的动向。
{"title":"People","authors":"","doi":"10.1038/s41587-024-02352-7","DOIUrl":"10.1038/s41587-024-02352-7","url":null,"abstract":"Recent moves of note in and around the biotech and pharma industries.","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1320-1320"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141986137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02363-4
Iris Marchal
{"title":"A base editor modifies bacterial genes in the guts of living mice","authors":"Iris Marchal","doi":"10.1038/s41587-024-02363-4","DOIUrl":"10.1038/s41587-024-02363-4","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1182-1182"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02365-2
Iris Marchal
{"title":"Bridge RNAs direct programmable DNA rearrangements","authors":"Iris Marchal","doi":"10.1038/s41587-024-02365-2","DOIUrl":"10.1038/s41587-024-02365-2","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1182-1182"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02364-3
Iris Marchal
{"title":"Joint profiling of drug–chromatin binding and epigenetic landscapes in single cells","authors":"Iris Marchal","doi":"10.1038/s41587-024-02364-3","DOIUrl":"10.1038/s41587-024-02364-3","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1182-1182"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02351-8
Mabel Andalón, Catherine de Fontenay, Donna K. Ginther, Kwanghui Lim
The rise in team size in academic science has generated an unintended side effect: junior scientists are less likely to secure research funding or obtain tenure and are more likely to leave academia.
{"title":"The rise of teamwork and career prospects in academic science","authors":"Mabel Andalón, Catherine de Fontenay, Donna K. Ginther, Kwanghui Lim","doi":"10.1038/s41587-024-02351-8","DOIUrl":"10.1038/s41587-024-02351-8","url":null,"abstract":"The rise in team size in academic science has generated an unintended side effect: junior scientists are less likely to secure research funding or obtain tenure and are more likely to leave academia.","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1314-1319"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14DOI: 10.1038/s41587-024-02310-3
{"title":"From Bench to Podcast: Sean Johnson","authors":"","doi":"10.1038/s41587-024-02310-3","DOIUrl":"10.1038/s41587-024-02310-3","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"42 8","pages":"1189-1189"},"PeriodicalIF":33.1,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-12DOI: 10.1038/s41587-024-02383-0
Nicolas Mathis, Ahmed Allam, András Tálas, Lucas Kissling, Elena Benvenuto, Lukas Schmidheini, Ruben Schep, Tanav Damodharan, Zsolt Balázs, Sharan Janjuha, Eleonora I Ioannidi, Desirée Böck, Bas van Steensel, Michael Krauthammer, Gerald Schwank
{"title":"Publisher Correction: Machine learning prediction of prime editing efficiency across diverse chromatin contexts.","authors":"Nicolas Mathis, Ahmed Allam, András Tálas, Lucas Kissling, Elena Benvenuto, Lukas Schmidheini, Ruben Schep, Tanav Damodharan, Zsolt Balázs, Sharan Janjuha, Eleonora I Ioannidi, Desirée Böck, Bas van Steensel, Michael Krauthammer, Gerald Schwank","doi":"10.1038/s41587-024-02383-0","DOIUrl":"10.1038/s41587-024-02383-0","url":null,"abstract":"","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":" ","pages":""},"PeriodicalIF":33.1,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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