Nutrition and health最新文献

Background & Aims: University students are prone to changes in their health status and lifestyle due to changes in their living environment and associated stress and anxiety. These changes may affect them in later life. This study utilized a cross-sectional study among Japanese female university students to examine dietary factors affecting their fecal microbiota. Methods: Sixty-eight healthy female university students were evaluated using an eating behavior assessment and diet history questionnaire. The 12-component Japanese diet index (JDI-12) was then calculated. A quantitative real-time PCR method was used to analyze the predominant bacterial species in the gut, and the Firmicutes/Bacteroidetes ratio (F/B ratio) at the phylum level was calculated. The partial correlation between the fecal microbiota and eating behavior abnormality score was assessed, and dietary habits associated with the F/B ratio were analyzed. Results: A significant correlation was identified between F/B ratios and the eating behavior abnormality score (r = 0.26, FDR = 0.064). Additionally, multiple regression analysis identified a negative correlation trend between the F/B ratio and JDI-12 score (β = -0.22; p = 0.091), and exploratory analysis found a negative association between the F/B ratio and consumption of beef and pork, one of the less beneficial JDI-12 components (β = -0.33, FDR = 0.120). Conclusion: In healthy female university students, there was a positive correlation between eating behavior abnormality and the F/B ratio, indicating that adherence to the Japanese diet pattern may be associated with a lower F/B ratio.

Background Diosgenin, extracted from Dioscorea esculenta, has been reported to decrease prostaglandin E₂ (PGE₂) levels and any other inflammatory cytokine in rodents. However, it is still unclear whether D. esculenta intake suppressed PGE₂ production and menstrual pain and premenstrual syndrome (PMS) in younger female. Aim This study aims to investigate the effect of D. esculenta intake on PGE₂ and cytochrome c oxidase subunit 2 (COX-2) levels and on menstrual pain and PMS in young women. This is a randomized, double-blind, placebo-controlled, crossover study. Methods Ten healthy young females were administered either a placebo or D. esculenta (300 mg/day) for 4 weeks, followed by a 4-week washout period. Fasting blood sample was taken from the fingertips on the second day of menstrual cycle began and obtained 24h before the last D. esculenta to avoid acute effects. Participants then switched treatments for 4 weeks as a second trial. Plasma PGE₂ and COX-2 levels were measured before and after each trial. The visual analogue scale (VAS), McGill pain questionnaire (MPQ), and Daily Record of Severity of Problems (DRSP) were also evaluated. The study was set and conducted from 2019 to 2020. Results PGE₂ and COX-2 levels significantly decreased after D. esculenta intake compared to placebo (p = 0.038, p = 0.042 each). The VAS and DRSP scores were also significantly lower after D. esculenta intake (p = 0.046, p = 0.035 each). Conclusion Four-week D. esculenta intake suppressed PGE₂ and COX-2 levels resulting in an improvement in PMS symptoms and menstrual pain in young women.

Background: Increased consumption of ultra-processed foods and drinks high in unhealthy fats, salt and sugar is a major driver behind rising non-communicable disease rates in Asia-Pacific. Urban residence is considered a risk factor for increased consumption of these products; yet, evidence on consumption behaviours and drivers from urban populations in the region remains limited. Aim: To understand perceptions and drivers of unhealthy fats, salt and sugar foods and drinks consumption and eating out behaviours in Yogyakarta city, Indonesia. Methods: In-depth qualitative data were collected through open-ended interviews and prolonged interactions in the local food environment, from a purposeful sample (N = 45) equally distributed across three urban communities. Data were analysed according to the principles of content analysis and following an iterative approach. Results: Despite showing high nutritional health awareness, respondents and their household members consumed ultra-processed foods high in unhealthy fats, salt and sugar regularly. Home consumption of these products was based primarily on economic considerations and convenience, but also related to attending requests from other family members, individual preferences and tastes, and social functions. Similarly, despite a reported preference for home-cooked traditional foods, several participants or their family members would frequently eat ready-made meals away from home, due to conflicting school or work commitments. Discussion: Results suggest that public health interventions focused on nutrition education among Indonesian communities should be coupled with measures addressing urban food environment characteristics that promote the consumption of unhealthy diets, be tailored to specific age groups, and leverage traditional food cultures.

Introduction: Vitamin A is one of the vitamins that is suggested as adjuvant therapy in viral infections due to its immune enhancing role. In the present clinical trial, we intended to assess the effect of vitamin A supplementation on Coronavirus disease-2019 (COVID-19) in hospitalized patients.

Methods: The present pilot randomized controlled clinical trial was conducted on 30 hospitalized patients with COVID-19. Patients in the intervention group received 50000 IU/day intramuscular vitamin A for a maximum of two weeks. Patients in the control group continued their common treatment protocols. All participants were followed up until discharge from the hospital or death. The primary outcome of the study was time to achieve clinical response based on the six classes of an ordinal scale. Time to clinical response was calculated based on the days needed to improve two scores on the scale or patient's discharge.

Results: The time to clinical response was not significantly different between the two groups (7.23 ± 2.14 vs. 6.75 ± 1.85 days, respectively, p = 0.48). There was no significant difference between the groups regarding clinical response (hazard ratio: 1.76 [95% CI: 0.73, 4.26]). There were no significant differences between groups regarding the need for mechanical ventilation, duration of hospitalization, or death in the hospital.

Conclusion: The results of this pilot clinical trial showed no benefit of vitamin A compared with the common treatment on outcome severity in hospitalized patients with COVID-19. Although the results are negative, there is still a great need for future clinical studies to provide a higher level of evidence.

Study purpose: this study aims to analyze QOL and psychosocial impact on patients with blood disorders.

Methods: A cross-sectional survey design is adopted in this study. The survey questionnaire included SF-36 form for measuring quality of life (QOL), along with psychosocial impact assessment scale. Adult patients with different types of blood disorders were recruited for the survey. Out of the 417 responses received, 389 were considered for data analysis and the remaining were avoided due to incomplete data.

Results: In terms of psychosocial impact scales, the highest mean is observed for financial stress (4.09 ± 1.22), followed by social exclusion (3.76 ± 1.19) and relationship challenges (3.31 ± 1.18). Among the QOL scales, the highest mean was observed for pain (3.81 ± 1.17), followed by physical functioning (3.68 ± 1.12). Statistically significant differences (p < 0.05) were observed among the participants groups characterized by age and type of disorder. Strong positive correlations between social exclusion and general health (r = 0.513), as well as pain and relationship challenges (r = 0.735) were observed.

Conclusion: Given the existing challenges in social exclusion, poor awareness, and support there is a need to develop comprehensive and personalized treatment plans integrating physical and mental support, awareness creation, and financial support.

Background: Self-compassion is a prevalent factor that has been explored in eating behaviour and weight loss literature. The present study explored the potential relationship between self-compassion and reasons individuals stop eating.

Method: Two hundred and eighty-three participants were recruited from social media platforms and a research participation scheme at a university in the West Midlands, UK, and completed questionnaires on self-compassion and reasons individuals stop eating.

Results: The findings suggested that self-compassion was negatively associated with decreased food appeal, self-consciousness, and decreased food priority, whilst being positively associated with physical satisfaction.

Conclusion: Self-compassion plays a prevalent role in the reasons individuals stop eating, and future research should continue exploring the effect of self-compassion on eating behaviour regulation.

Background: Proteins are essential for the maintenance, repair, and growth of muscle mass. This is particularly important for master athletes because aging has been associated with loss of muscle mass, function, and strength. Moreover, the timing of intake has been shown important for the best protein utilization. Aim: To analyze timing, quantity, and source of dietary protein in competitive master athletes according to current recommendations. Methods: Twenty-one male master swimmers (47.9 ± 10.0 years; 79.2 ± 6.5 kg; 179.1 ± 5.5 cm; 23.5 ± 4.9% body fat; 73.3 ± 4.2% lean mass) participated in this cross-sectional study. Protein intake was analyzed based on 7-day food records, regarding quantity, timing, and sources of intake. Protein intake was evaluated according to current international sports nutrition guidelines, including the International Society of Sports Nutrition Position Stand. Body fat (%) and lean mass (%) were evaluated using dual-energy X-ray absorptiometry. Results: Participants' mean protein intakes were 1.9 ± 0.5 g/kg/day, 0.6 ± 0.2 g/kg/meal post-training, and 33.5 ± 23.9 g during the pre-sleep period. Daily intake was within the recommended values of 1.4 and 2.0 g/kg/day (p = 0.01 and 0.147, respectively). Mean pre-sleep intake was within the recommendation values of 30-40 g (p = 0.28 and 0.147, respectively). Most of the daily protein intake was consumed at lunch (66.7 ± 6.9 g) and dinner (48.0 ± 4.5 g). Regarding protein sources, intakes from animal, vegetal, and supplements were, respectively, 65.7%, 29.2%, and 5.1%. Conclusion: Master swimmers presented a total protein intake within the recommendations for a daily basis, but the majority of intake was at lunch and dinner. Protein intake could be better distributed throughout the day to optimize protein synthesis. Guidance on daily protein intake distribution should be reinforced in clinical practice.

The purpose of this content analysis was to ascertain what nutrition advice or information is freely available on a global scale through each National Governing Body (NGB) webpage. In total, 52 NGBs and the International Federation of Gymnastics (FIG) were identified based on the FIG November 2022 world rankings for both male and female athletes in all disciplines. Concluding observations were that publicly available nutrition advice is limited across the global gymnastics platforms. Conflicting advice was also identified within some organisations surrounding the weighing of gymnasts for hydration purposes and some macronutrient discrepancies thus, potentially impacting the clarity of the message for the reader. Based on this content analysis recommendations for future practice include providing clarity and provision of tools to measure hydration, dietary recommendations should be clear and specific, and a more centralised approach to standardise advice and publicly available information.

Background: Geographically Isolated and Disadvantaged Areas (GIDA) are communities physically and socioeconomically separated from mainstream society (non-GIDA) and lack comprehensive nutrition and health assessments. Aim: This study aimed to assess the nutritional and health status and determine the factors associated with chronic energy deficiency (CED) and overweight/obesity among adults, 20-59 years old, residing in GIDA and non-GIDA. Methods: Data of the 20,381 adults collected in the Expanded National Nutrition Survey were analyzed. Multivariate logistic regression analyses were performed to determine the predictors of CED and overweight/obesity. Results: Chronic energy deficiency and current smoking were significantly higher in GIDA, while overweight/obesity, alcohol consumption, elevated blood pressure, and insufficient physical activity were higher in non-GIDA (p < 0.001). Higher odds of CED was associated with food insecurity (adjusted odds ratio [AOR]: 1.5, p < 0.001; AOR: 1.3, p < 0.001) and current smoking (AOR: 1.4, p = 0.001; AOR: 1.3, p < 0.001) in both GIDA and non-GIDA while poor wealth (AOR: 1.5, p < 0.001) only in non-GIDA. Higher odds of overweight/obesity was associated with higher age ≥30 years (AOR: 2.1, p < 0.001; AOR: 1.9, p < 0.001), being female (AOR: 1.7, p < 0.001; AOR: 1.3, p < 0.001), with grade level completed (AOR: 1.7, p = 0.004; AOR: 1.2, p = 0.038), urban residence (AOR: 1.2, p = 0.035; AOR: 1.3, p < 0.001), hypertension (AOR: 2.4, p < 0.001; AOR: 2.3, p < 0.001), and insufficient physical activity (AOR: 1.1, p = 0.020; AOR: 1.1, p = 0.027) in both GIDA and non-GIDA. Conclusions: Malnutrition affects GIDA in almost the same magnitude. The double burden of malnutrition and health inequity in GIDA underscores the greater need for comprehensive policies and stronger programs directed toward underserved areas.

Background and aims: This exploratory observational prospective study aimed to evaluate fat-soluble vitamin plasma levels during hospital admission and its relation with the development of malnutrition and complications in polytrauma patients, considering the protocolized multivitamin supplementation during intensive care unit (ICU) admission.

Methods: In 49 well-nourished polytrauma (injury severity score ≥ 16) patients admitted to the ICU of two level-1 trauma centers, vitamin A, D, and E levels were assessed weekly during hospital stay. All patients received multivitamin supplementation during ICU stay. Linear mixed-effect models were used to assess a trend in vitamin levels over time during hospital stay. Mixed-effects logistic regression analysis was performed to relate vitamin concentrations with malnutrition, defined as a subjective global assessment score ≤5, and complications.

Results: Vitamin A levels increased 0.17 µmol/L per week (95% confidence interval 0.12-0.22, p < 0.001), vitamin D levels increased 1.49 nmol/L per week (95% confidence interval 0.64-2.33, p < 0.01), vitamin E levels increased 1.17 µmol/L per week (95% confidence interval 0.61-1.73, p < 0.001) during hospital stay (29 ± 17 days). Vitamin levels were not related to malnutrition or complications during hospital stay.

Conclusion: Vitamin A, D, and E levels increased due to supplementation during hospital admission. Plasma levels of vitamins A, D, and E do not seem to be useful as biomarkers for the nutritional status of polytrauma patients during hospital stay. No correlation with complications could be demonstrated.