Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-9-793
V. Kumar, A. Saxena, M. Chakrabarty, B. Ray
Editorial Biomedical research progresses by leaps and bounds and every day, in the lab, witnesses reams of data be- ing added to the already existing database. Researchers or scholars often find themselves at sea decid- ing the right window of expression for their work and also struggling to find their target audience. With scant opportunities for budding scholars to acquaint themselves to scientific writing and publishing skills, it is the need of the hour to introduce the greenhorns to the outlines of the various categories of scientific writ- ing and what each category of publi- cation entails. Conclusion The main motive of a researcher is to disseminate his/her work to the soci- ety, other scholars, academicians and students. Inappropriate design of the manuscript may lead to delay in pub- lication or non-publication. There- fore, it becomes essential to know which category of scientific literature your work falls in. Editorial A scientific paper is a written and published report presenting original research results. The purpose of sci- entific papers is to communicate the results and their inference to a wider scientific community 1 . It is a tool by which the authors express informa- tion at hand in a professional man- ner. A scientific paper debates the raised topics, shares the information gathered, statistically analyses the information and draws the readers' attention to the most pertinent con- clusions 2 . While drafting a scientific manuscript, the researcher should pay attention to quality, lucidity, sim- plicity, communication and language, which are its salient characteristics. As every paper is different in its con- tent and so is judged by different yardsticks, the researcher should be aware of the type of manuscript he/ she is drafting to serve the specific purpose. The manuscript prepared for sub- mission should be organised in the best possible way to exhibit the au- thor's research work lucidly. Most of the scientific articles contain subheads arranged as introduction, methods, results, discussion and con- clusion (IMRAD), which is a popular structured format, often adhered to. However, there are a few exceptions like case reports and technical inno- vations that do not fit into the IMRAD format 3,4 .
{"title":"Let your work decide the shape of the manuscript","authors":"V. Kumar, A. Saxena, M. Chakrabarty, B. Ray","doi":"10.13172/2052-0077-2-9-793","DOIUrl":"https://doi.org/10.13172/2052-0077-2-9-793","url":null,"abstract":"Editorial Biomedical research progresses by leaps and bounds and every day, in the lab, witnesses reams of data be- ing added to the already existing database. Researchers or scholars often find themselves at sea decid- ing the right window of expression for their work and also struggling to find their target audience. With scant opportunities for budding scholars to acquaint themselves to scientific writing and publishing skills, it is the need of the hour to introduce the greenhorns to the outlines of the various categories of scientific writ- ing and what each category of publi- cation entails. Conclusion The main motive of a researcher is to disseminate his/her work to the soci- ety, other scholars, academicians and students. Inappropriate design of the manuscript may lead to delay in pub- lication or non-publication. There- fore, it becomes essential to know which category of scientific literature your work falls in. Editorial A scientific paper is a written and published report presenting original research results. The purpose of sci- entific papers is to communicate the results and their inference to a wider scientific community 1 . It is a tool by which the authors express informa- tion at hand in a professional man- ner. A scientific paper debates the raised topics, shares the information gathered, statistically analyses the information and draws the readers' attention to the most pertinent con- clusions 2 . While drafting a scientific manuscript, the researcher should pay attention to quality, lucidity, sim- plicity, communication and language, which are its salient characteristics. As every paper is different in its con- tent and so is judged by different yardsticks, the researcher should be aware of the type of manuscript he/ she is drafting to serve the specific purpose. The manuscript prepared for sub- mission should be organised in the best possible way to exhibit the au- thor's research work lucidly. Most of the scientific articles contain subheads arranged as introduction, methods, results, discussion and con- clusion (IMRAD), which is a popular structured format, often adhered to. However, there are a few exceptions like case reports and technical inno- vations that do not fit into the IMRAD format 3,4 .","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88912576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-9-792
R. Swamy, N. Kumar, S. Nayak, R. Mohandas, P. Jyothsna, G. Anitha
Introduction The course and location of ansa cervicalis of the neck often vary. Because of its closeness with the major vessels and nerves of the neck, any variation in its pattern is of great clinical and surgical importance. This paper reports a case of an unusual looping pattern of ansa cervicalis. Case report We report here an unusual looping pattern of ansa cervicalis. The inferior root of ansa cervicalis, instead of joining the superior root as a single nerve, had both the C2 and C3 components of it joined to the superior root separately without uniting each other. Due to this, two loops of AC were formed superior and inferior. Conclusion Since the branches of ansa cervicalis are often chosen for nerve–muscle transplantation in the treatment of paralysed larynx, and some of the branches arise from the loop of the AC, an abnormal looping pattern may hinder such surgical procedures. Therefore, it is essential to the surgeons to be familiar with its unusual variations.
{"title":"Unusual looping pattern of ansa cervicalis: case report","authors":"R. Swamy, N. Kumar, S. Nayak, R. Mohandas, P. Jyothsna, G. Anitha","doi":"10.13172/2052-0077-2-9-792","DOIUrl":"https://doi.org/10.13172/2052-0077-2-9-792","url":null,"abstract":"Introduction The course and location of ansa cervicalis of the neck often vary. Because of its closeness with the major vessels and nerves of the neck, any variation in its pattern is of great clinical and surgical importance. This paper reports a case of an unusual looping pattern of ansa cervicalis. Case report We report here an unusual looping pattern of ansa cervicalis. The inferior root of ansa cervicalis, instead of joining the superior root as a single nerve, had both the C2 and C3 components of it joined to the superior root separately without uniting each other. Due to this, two loops of AC were formed superior and inferior. Conclusion Since the branches of ansa cervicalis are often chosen for nerve–muscle transplantation in the treatment of paralysed larynx, and some of the branches arise from the loop of the AC, an abnormal looping pattern may hinder such surgical procedures. Therefore, it is essential to the surgeons to be familiar with its unusual variations.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78523490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-9-801
F. Zambrana, B. Bathal, M. Sereno, C. Gómez-Raposo, M. López-Gómez, M. Merino, E. Casado
recurrence appeared. The patient was diagnosed with primary classic Kaposi’s Sarcoma (Type I) limited to the supraglottis. Conclusion Classic-type Kaposi’s sarcoma is usually slow growing and does not impair quality of life and survival in the short term, but aggressive forms may be life threatening and should be treated urgently. Systemic chemotherapy with pegylated liposomal doxorubicin is an affective and well-tolerated strategy also for limited-stage disease with rapid progression, however.
{"title":"Durable complete response of classic Kaposi's sarcoma of the supraglottis with pegylated liposomal doxorubicin","authors":"F. Zambrana, B. Bathal, M. Sereno, C. Gómez-Raposo, M. López-Gómez, M. Merino, E. Casado","doi":"10.13172/2052-0077-2-9-801","DOIUrl":"https://doi.org/10.13172/2052-0077-2-9-801","url":null,"abstract":"recurrence appeared. The patient was diagnosed with primary classic Kaposi’s Sarcoma (Type I) limited to the supraglottis. Conclusion Classic-type Kaposi’s sarcoma is usually slow growing and does not impair quality of life and survival in the short term, but aggressive forms may be life threatening and should be treated urgently. Systemic chemotherapy with pegylated liposomal doxorubicin is an affective and well-tolerated strategy also for limited-stage disease with rapid progression, however.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73302405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-9-796
I. Alagkiozidis, G. Salame, Jonathan Somma, M. Herskovitz, D. Levin
representing extra-uterine foci of leiomyomatous lesions of variable size and locations and variable delay in presentation after initial diagnosis of uterine fibroids. The nature of benign metastasizing leiomyoma has been debated since it was first reported in 1939, and only a few dozen cases have been reported in the English literature 1 . Recent findings at the proteomic and genomic level demonstrate that the metastatic lesions are clonally related to the primary uterine fibroids and suggest that their pathogenesis relies on metastatic spread and not on simultaneous multifocal appearance 2 . Therefore, these tumours could be regarded as borderline tumours or tumours with low malignant potential. Due to the rarity of these cases, there is currently no consensus on their management. The high expression of oestrogen (ER) and progesterone (PR) receptors supports the use of hormonal therapy. Surgical intervention can be challenging due to the recurrent, often disseminated nature of these tumours and their aberrant vascularity. Over the last few decades, uterine artery embolisation has emerged as an established treatment for primary uterine fibroids. This case suggests that angiography and embolisation should be considered in the management of the patients with BML in an attempt to avoid surgical intervention or decrease the risk for perioperative bleeding.
{"title":"Perioperative transcatheter embolisation of a locally recurrent metastatic uterine leiomyoma","authors":"I. Alagkiozidis, G. Salame, Jonathan Somma, M. Herskovitz, D. Levin","doi":"10.13172/2052-0077-2-9-796","DOIUrl":"https://doi.org/10.13172/2052-0077-2-9-796","url":null,"abstract":"representing extra-uterine foci of leiomyomatous lesions of variable size and locations and variable delay in presentation after initial diagnosis of uterine fibroids. The nature of benign metastasizing leiomyoma has been debated since it was first reported in 1939, and only a few dozen cases have been reported in the English literature 1 . Recent findings at the proteomic and genomic level demonstrate that the metastatic lesions are clonally related to the primary uterine fibroids and suggest that their pathogenesis relies on metastatic spread and not on simultaneous multifocal appearance 2 . Therefore, these tumours could be regarded as borderline tumours or tumours with low malignant potential. Due to the rarity of these cases, there is currently no consensus on their management. The high expression of oestrogen (ER) and progesterone (PR) receptors supports the use of hormonal therapy. Surgical intervention can be challenging due to the recurrent, often disseminated nature of these tumours and their aberrant vascularity. Over the last few decades, uterine artery embolisation has emerged as an established treatment for primary uterine fibroids. This case suggests that angiography and embolisation should be considered in the management of the patients with BML in an attempt to avoid surgical intervention or decrease the risk for perioperative bleeding.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85178486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-8-789
AF Snow, M. Vannahme, A. Pullyblank
Introduction Hepatic artery aneurysms are among the most common visceral artery aneurysms although still relatively rare. Repair of aneurysms greater than 2 cm in diameter is important due to the high rate of rupture and associated mortality. Here we present a case of a sudden rupture of a hepatic artery aneurysm after presentation with a perforated gangrenous appendicitis. There is increasing evidence that expansion and rupture of abdominal aortic aneurysm is related to degradation of elastin and collagen by matrix metal-loproteinases. Elastin degradation leads to expansion whilst collagen degradation leads to rupture. Additionally , matrix metalloproteinases activity has been shown to be upreg-ulated by both sepsis and peritonitis. Case report An 80-year-old Caucasian man presented as an emergency with a 7-day history of central abdominal pain that had moved to the right iliac fossa and increased in severity over the last 2 days. His admission chest radio-graph was unremarkable. A diagnosis of acute appendicitis was made and the patient was booked at 01:00 for a laparoscopy and appendicectomy on the emergency list the following morning. The patient required a total of 11 units of packed red cells. He made a slow but uneventful recovery and was discharged 19 days later.
{"title":"Ruptured hepatic artery aneurysm precipitated by gangrenous perforated appendicitis: A case report","authors":"AF Snow, M. Vannahme, A. Pullyblank","doi":"10.13172/2052-0077-2-8-789","DOIUrl":"https://doi.org/10.13172/2052-0077-2-8-789","url":null,"abstract":"Introduction Hepatic artery aneurysms are among the most common visceral artery aneurysms although still relatively rare. Repair of aneurysms greater than 2 cm in diameter is important due to the high rate of rupture and associated mortality. Here we present a case of a sudden rupture of a hepatic artery aneurysm after presentation with a perforated gangrenous appendicitis. There is increasing evidence that expansion and rupture of abdominal aortic aneurysm is related to degradation of elastin and collagen by matrix metal-loproteinases. Elastin degradation leads to expansion whilst collagen degradation leads to rupture. Additionally , matrix metalloproteinases activity has been shown to be upreg-ulated by both sepsis and peritonitis. Case report An 80-year-old Caucasian man presented as an emergency with a 7-day history of central abdominal pain that had moved to the right iliac fossa and increased in severity over the last 2 days. His admission chest radio-graph was unremarkable. A diagnosis of acute appendicitis was made and the patient was booked at 01:00 for a laparoscopy and appendicectomy on the emergency list the following morning. The patient required a total of 11 units of packed red cells. He made a slow but uneventful recovery and was discharged 19 days later.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88515883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-10-802
H. Shojaei, C. Albertin, A. Schaus, A. Al-Niaimi
Introduction Cellular angiofibroma is a rare benign mesenchymal tumour that occurs in the subepithelial myxoid stromal zone of the vulvovaginal region. We report a case of painful angiofibroma in a 52-year-old morbidly obese female, in the left labia. Case report A 52-year-old morbidly obese (body mass index of 67) female was referred to our gynaecologic oncology clinic with a 3-year history of a large, painful, pendulous left vulvar mass. Magnetic resonance imaging of the lesion helped confirm that the mass did not represent a hernia and was fibrous in nature. Resection revealed a 12 × 12 × 9 cm, a 187-gram encapsulated mass. Histologically, it was a well circumscribed tumour composed of hyalinised blood vessels and collagen bundles, exhibiting characteristic immunohistochemical features of a cellular angiofibroma. Conclusion Angiofibroma of the vulva is a rare benign encapsulated mass, yet hypervascular. Its diagnosis in a morbidly obese patient is challenging and necessitates magnetic resonance imaging or CT scan. Its surgical removal needs precision and meticulousness especially in a patient with multiple comorbidities.
{"title":"Painful cellular angiofibroma of the vulva: case report","authors":"H. Shojaei, C. Albertin, A. Schaus, A. Al-Niaimi","doi":"10.13172/2052-0077-2-10-802","DOIUrl":"https://doi.org/10.13172/2052-0077-2-10-802","url":null,"abstract":"Introduction Cellular angiofibroma is a rare benign mesenchymal tumour that occurs in the subepithelial myxoid stromal zone of the vulvovaginal region. We report a case of painful angiofibroma in a 52-year-old morbidly obese female, in the left labia. Case report A 52-year-old morbidly obese (body mass index of 67) female was referred to our gynaecologic oncology clinic with a 3-year history of a large, painful, pendulous left vulvar mass. Magnetic resonance imaging of the lesion helped confirm that the mass did not represent a hernia and was fibrous in nature. Resection revealed a 12 × 12 × 9 cm, a 187-gram encapsulated mass. Histologically, it was a well circumscribed tumour composed of hyalinised blood vessels and collagen bundles, exhibiting characteristic immunohistochemical features of a cellular angiofibroma. Conclusion Angiofibroma of the vulva is a rare benign encapsulated mass, yet hypervascular. Its diagnosis in a morbidly obese patient is challenging and necessitates magnetic resonance imaging or CT scan. Its surgical removal needs precision and meticulousness especially in a patient with multiple comorbidities.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91242846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-9-798
E. Ashton, B. Corbett, C. Morosky
Introduction This paper reports a case of hemihysterectomy for placenta accreta in a bicornuate uterus. Case report This is a case of a 29-year-old G3P1021 whose pregnancy was complicated by a bicornuate uterus, history of cervical incompetence with cerclage placement, and retained placenta in the right uterine horn after a term vacuum-assisted vaginal delivery. Magnetic resonance imaging demonstrated placenta increta in the right uterine horn and the patient underwent an abdominal supracervical hemi-hysterectomy and right salpingectomy. Conclusion Our patient’s three D&C procedures and her uterine anomaly likely contributed to her placenta accreta and need for this unique fertility preserving surgery.
{"title":"Hemi-hysterectomy for placenta accreta in a bicornuate uterus","authors":"E. Ashton, B. Corbett, C. Morosky","doi":"10.13172/2052-0077-2-9-798","DOIUrl":"https://doi.org/10.13172/2052-0077-2-9-798","url":null,"abstract":"Introduction This paper reports a case of hemihysterectomy for placenta accreta in a bicornuate uterus. Case report This is a case of a 29-year-old G3P1021 whose pregnancy was complicated by a bicornuate uterus, history of cervical incompetence with cerclage placement, and retained placenta in the right uterine horn after a term vacuum-assisted vaginal delivery. Magnetic resonance imaging demonstrated placenta increta in the right uterine horn and the patient underwent an abdominal supracervical hemi-hysterectomy and right salpingectomy. Conclusion Our patient’s three D&C procedures and her uterine anomaly likely contributed to her placenta accreta and need for this unique fertility preserving surgery.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"193 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73758855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-9-795
M. Mittal, N. Jha, V. Mehta, R. Suri, M. Sinha, N. Bhambri, B. Thukral
Introduction Solid pseudopapillary tumour of the pancreas, though rare, is a low-grade malignancy with indolent behaviour. It is encountered predominantly in young females, although it has been seen in males and children. Most patients present with vague non- specificabdominalpainresultingin� delayed diagnosis. Therefore diagno- sis of this tumour may be an inciden- talfindingduringdiagnosticimaging� procedures or maybe assumed when a young women presents with an asymptomatic palpable mass. Traditionally the presence of a large bulky pancreatic tumour in a child should raise suspicion of the diagno- sis of pancreotoblastoma. This study reports a case of a solid pseudopapil- lary tumour of the pancreas in a child. Case report We present a case of an eight-year-old child presenting with pain and a lump in the epigastric region. Computerised tomography was subsequently per- formed to localise the mass accu- rately. Computed tomography showed a minimally enhancing solid mass in the head and proximal body of the pancreas compressing the second and third part of the duodenum and measuring 7.2 × 6.9 × 6.4 cm. Conclusion This case report highlights the fact that with characteristic imaging fea- tures the diagnosis of solid pseudo- papillary tumour of the pancreas should be considered irrespective of theageprofileofthepatient.
{"title":"Solid pseudopapillary tumour of the pancreas in a child: case report","authors":"M. Mittal, N. Jha, V. Mehta, R. Suri, M. Sinha, N. Bhambri, B. Thukral","doi":"10.13172/2052-0077-2-9-795","DOIUrl":"https://doi.org/10.13172/2052-0077-2-9-795","url":null,"abstract":"Introduction Solid pseudopapillary tumour of the pancreas, though rare, is a low-grade malignancy with indolent behaviour. It is encountered predominantly in young females, although it has been seen in males and children. Most patients present with vague non- specificabdominalpainresultingin� delayed diagnosis. Therefore diagno- sis of this tumour may be an inciden- talfindingduringdiagnosticimaging� procedures or maybe assumed when a young women presents with an asymptomatic palpable mass. Traditionally the presence of a large bulky pancreatic tumour in a child should raise suspicion of the diagno- sis of pancreotoblastoma. This study reports a case of a solid pseudopapil- lary tumour of the pancreas in a child. Case report We present a case of an eight-year-old child presenting with pain and a lump in the epigastric region. Computerised tomography was subsequently per- formed to localise the mass accu- rately. Computed tomography showed a minimally enhancing solid mass in the head and proximal body of the pancreas compressing the second and third part of the duodenum and measuring 7.2 × 6.9 × 6.4 cm. Conclusion This case report highlights the fact that with characteristic imaging fea- tures the diagnosis of solid pseudo- papillary tumour of the pancreas should be considered irrespective of theageprofileofthepatient.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"459 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83031195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-9-799
A. Sauer, D. Gaucher, T. Bourcier, C. Speeg-Schatz
Department of Ophthalmology, Hôpitaux Universitaires de Strasbourg, Nouvel Hopital Civil, France Abstract Introduction Choroidal metastasis is a very rare clinical manifestation of thyroid cancer. The goal of our work is to report a case of late choroidal metastasis from papillary thyroid carcinoma. Case report A 59-year-old woman who had been treated for papillary thyroid carcinoma 3 years earlier presented for evaluation of vision loss in the right eye. A fundoscopic examination revealed a choroidal mass which had the typical characteristics of a metastatic lesion. After exclusion of any other neoplastic lesion, metastatic lesion from papillary thyroid carcinoma was diagnosed. The patient was treated with a combination of brachytherapy and chemotherapy. Despite this treatment, the patient complained about two other metastatic lesions (lung and hip) a few months later. Conclusion Papillary thyroid carcinoma can metastasise to the choroid many years after the initial diagnosis.
{"title":"Choroidal metastasis as a rare feature of papillary thyroid carcinoma","authors":"A. Sauer, D. Gaucher, T. Bourcier, C. Speeg-Schatz","doi":"10.13172/2052-0077-2-9-799","DOIUrl":"https://doi.org/10.13172/2052-0077-2-9-799","url":null,"abstract":"Department of Ophthalmology, Hôpitaux Universitaires de Strasbourg, Nouvel Hopital Civil, France Abstract Introduction Choroidal metastasis is a very rare clinical manifestation of thyroid cancer. The goal of our work is to report a case of late choroidal metastasis from papillary thyroid carcinoma. Case report A 59-year-old woman who had been treated for papillary thyroid carcinoma 3 years earlier presented for evaluation of vision loss in the right eye. A fundoscopic examination revealed a choroidal mass which had the typical characteristics of a metastatic lesion. After exclusion of any other neoplastic lesion, metastatic lesion from papillary thyroid carcinoma was diagnosed. The patient was treated with a combination of brachytherapy and chemotherapy. Despite this treatment, the patient complained about two other metastatic lesions (lung and hip) a few months later. Conclusion Papillary thyroid carcinoma can metastasise to the choroid many years after the initial diagnosis.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89065185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-09-01DOI: 10.13172/2052-0077-2-9-797
P. Hantson, X. Wittebole, P. Bergh
Abstract Introduction This article reports a case of the difficulty to differentiate between critical illness polyneuropathy and axonal Guillain–Barre syndrome when triggered by subarachnoid haemorrhage. Case report An 81-year-old man was admitted comatose (Glasgow coma scale score 4/15) after a subarachnoid haemorrhage. His neurological condition gradually improved with as best motor response (M4) withdrawal from pain at the four limbs. The patient developed early complications such as septicaemia and acute renal injury. After 3 weeks, a marked decrease of motor response (M1) was noted in the lower, and, to lesser extent, upper limbs. Deep tendon reflexes were abolished. The cerebrospinal fluid examination showed elevated protein level. After electrophysiological examination, the diagnosis of acute motor axonal neuropathy, a variant of Guillain–Barre syndrome, was discussed versus critical illness polyneuropathy. Specific therapy for Guillain–Barre syndrome could not be administered. No significant motor recovery was observed after 7 months. Conclusion The distinction between critical illness polyneuropathy and Guillain– Barre syndrome remains difficult in critically ill patients. It is not known if subarachnoid haemorrhage could be considered as a possible triggering factor for Guillain–Barre syndrome.
{"title":"Critical illness polyneuropathy or axonal Guillain-Barré syndrome triggered by subarachnoid haemorrhage?","authors":"P. Hantson, X. Wittebole, P. Bergh","doi":"10.13172/2052-0077-2-9-797","DOIUrl":"https://doi.org/10.13172/2052-0077-2-9-797","url":null,"abstract":"Abstract Introduction This article reports a case of the difficulty to differentiate between critical illness polyneuropathy and axonal Guillain–Barre syndrome when triggered by subarachnoid haemorrhage. Case report An 81-year-old man was admitted comatose (Glasgow coma scale score 4/15) after a subarachnoid haemorrhage. His neurological condition gradually improved with as best motor response (M4) withdrawal from pain at the four limbs. The patient developed early complications such as septicaemia and acute renal injury. After 3 weeks, a marked decrease of motor response (M1) was noted in the lower, and, to lesser extent, upper limbs. Deep tendon reflexes were abolished. The cerebrospinal fluid examination showed elevated protein level. After electrophysiological examination, the diagnosis of acute motor axonal neuropathy, a variant of Guillain–Barre syndrome, was discussed versus critical illness polyneuropathy. Specific therapy for Guillain–Barre syndrome could not be administered. No significant motor recovery was observed after 7 months. Conclusion The distinction between critical illness polyneuropathy and Guillain– Barre syndrome remains difficult in critically ill patients. It is not known if subarachnoid haemorrhage could be considered as a possible triggering factor for Guillain–Barre syndrome.","PeriodicalId":19393,"journal":{"name":"OA Case Reports","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74019060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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