Pub Date : 2008-08-01DOI: 10.11263/JSOTP1982.27.92
M. Kataoka, J. Kido
{"title":"α2 Integrin polymorphism in drug-induced gingival overgrowth","authors":"M. Kataoka, J. Kido","doi":"10.11263/JSOTP1982.27.92","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.92","url":null,"abstract":"","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"27 1","pages":"92-96"},"PeriodicalIF":0.0,"publicationDate":"2008-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-08-01DOI: 10.11263/JSOTP1982.27.79
M. Ono, Naoko Ohno, K. Hasegawa, Shigeo Tanaka, M. Komiya, H. Matsumoto, A. Fujii, Y. Akimoto
The incidence of gingival overgrowth caused by calcium channel blockers was determined. The overgrowth was found in patients receiving amlodipine, diltiazem, manidipine, nicardipine, nifedipine and nisoldipine. The highest rate of gingival overgrowth was obtained by nifedipine (7.6%), followed by diltiazem (4.1%), manidipine (1.8%), amlodipine (1.l%), nisoldipine (1.1%) and nicardipine (0.5%). The rate of nifedipine-induced gingival overgrowth was significantly higher than those of amlodipine, manidipine, nicardipine and nisoldipine, but not diltiazem.
{"title":"Incidence of gingival overgrowth caused by calcium channel blockers","authors":"M. Ono, Naoko Ohno, K. Hasegawa, Shigeo Tanaka, M. Komiya, H. Matsumoto, A. Fujii, Y. Akimoto","doi":"10.11263/JSOTP1982.27.79","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.79","url":null,"abstract":"The incidence of gingival overgrowth caused by calcium channel blockers was determined. The overgrowth was found in patients receiving amlodipine, diltiazem, manidipine, nicardipine, nifedipine and nisoldipine. The highest rate of gingival overgrowth was obtained by nifedipine (7.6%), followed by diltiazem (4.1%), manidipine (1.8%), amlodipine (1.l%), nisoldipine (1.1%) and nicardipine (0.5%). The rate of nifedipine-induced gingival overgrowth was significantly higher than those of amlodipine, manidipine, nicardipine and nisoldipine, but not diltiazem.","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"27 1","pages":"79-85"},"PeriodicalIF":0.0,"publicationDate":"2008-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11263/JSOTP1982.27.79","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-08-01DOI: 10.11263/JSOTP1982.27.97
Pao‐Li Wang, T. Hattori
{"title":"The current study on drug-induced gingival overgrowth—an update study using a Kampo medicine","authors":"Pao‐Li Wang, T. Hattori","doi":"10.11263/JSOTP1982.27.97","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.97","url":null,"abstract":"","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"27 1","pages":"97-102"},"PeriodicalIF":0.0,"publicationDate":"2008-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-08-01DOI: 10.11263/JSOTP1982.27.131
Mie Mochizuki, Takashi Mishimagi, Itaru Sonoda, Yutaka Sato, N. Arai, T. Amagasa
{"title":"A case of facial erysipelas which caused by odontogenic infection","authors":"Mie Mochizuki, Takashi Mishimagi, Itaru Sonoda, Yutaka Sato, N. Arai, T. Amagasa","doi":"10.11263/JSOTP1982.27.131","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.131","url":null,"abstract":"","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"27 1","pages":"131-135"},"PeriodicalIF":0.0,"publicationDate":"2008-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kayoko Yamamoto, N. Yohkoh, Mieko Takahashi, Michiko Okada, Toru Endo, T. Chiba, H. Endoh, Kenji Kito, E. Suzuki, Mitsuko Morizuka, Noriaki Yoshida, Kuniko Tohyama, S. Ohkubo, Megumi Ohashi, Kiyotaka Uenaka
{"title":"Survey on trends in the use of analgesic anti-inflammatory medicines and anti-inflammatory enzyme medicines in dental practice","authors":"Kayoko Yamamoto, N. Yohkoh, Mieko Takahashi, Michiko Okada, Toru Endo, T. Chiba, H. Endoh, Kenji Kito, E. Suzuki, Mitsuko Morizuka, Noriaki Yoshida, Kuniko Tohyama, S. Ohkubo, Megumi Ohashi, Kiyotaka Uenaka","doi":"10.11263/JSOTP1982.27.9","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.9","url":null,"abstract":"","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"27 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2008-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-04-01DOI: 10.11263/JSOTP1982.27.17
A. Iwasaki, M. Miyake, K. Meguro, Masayuki Okamoto, T. Ogawa, Y. Ohbayashi, S. Nagahata
{"title":"Clinical evaluation of tooth extraction in patients undergoing antithrombotic therapy","authors":"A. Iwasaki, M. Miyake, K. Meguro, Masayuki Okamoto, T. Ogawa, Y. Ohbayashi, S. Nagahata","doi":"10.11263/JSOTP1982.27.17","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.17","url":null,"abstract":"","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"27 1","pages":"17-24"},"PeriodicalIF":0.0,"publicationDate":"2008-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-04-01DOI: 10.11263/JSOTP1982.27.25
M. Hori, R. Takeuchi, H. Matsumoto
{"title":"The effect of Insulin-like growth factor-I on cell cycle in human gingival fibroblasts from nifedipine responders and non-responders","authors":"M. Hori, R. Takeuchi, H. Matsumoto","doi":"10.11263/JSOTP1982.27.25","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.25","url":null,"abstract":"","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"19 1","pages":"25-35"},"PeriodicalIF":0.0,"publicationDate":"2008-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this study was to synthesize cyclopropene derivatives and evaluate their oral antimicrobial activities. Nine cyclopropene derivatives possessing various functional groups as substituents on a ring were prepared by rhodium-catalyzed cycloaddition reaction in moderate yields. Among them, six typical cyclopropenes were shown to have antimicrobial activities against Gram-positive and Gram-negative bacteria including Staphylococcus aureus, Bacillus cereus and Escherichia coli. We evaluated in turn their inhibitory effects against oral bacteria and all nine compounds were elucidated to have potent inhibitory effects on the growth of oral bacterial flora derived from human whole saliva under aerobic and anaerobic conditions. In addition, four typical cyclopropenes of these compounds were shown to exhibit strong antimicrobial activities against Porphyromonas gingivalis and Streptococcus sobrinus. These results indicate that cyclopropene derivatives were promising agents for the prevention and treatment of dental caries and periodontal diseases.
{"title":"The antimicrobial activity of cyclopropene derivatives towards oral bacteria","authors":"Hiroyasu Sato, H. Horie, Kahoru Taya, S. Hamada","doi":"10.11263/JSOTP1982.27.1","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.1","url":null,"abstract":"The aim of this study was to synthesize cyclopropene derivatives and evaluate their oral antimicrobial activities. Nine cyclopropene derivatives possessing various functional groups as substituents on a ring were prepared by rhodium-catalyzed cycloaddition reaction in moderate yields. Among them, six typical cyclopropenes were shown to have antimicrobial activities against Gram-positive and Gram-negative bacteria including Staphylococcus aureus, Bacillus cereus and Escherichia coli. We evaluated in turn their inhibitory effects against oral bacteria and all nine compounds were elucidated to have potent inhibitory effects on the growth of oral bacterial flora derived from human whole saliva under aerobic and anaerobic conditions. In addition, four typical cyclopropenes of these compounds were shown to exhibit strong antimicrobial activities against Porphyromonas gingivalis and Streptococcus sobrinus. These results indicate that cyclopropene derivatives were promising agents for the prevention and treatment of dental caries and periodontal diseases.","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"27 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2008-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-04-01DOI: 10.11263/JSOTP1982.27.53
Kosuke Hakozaki, H. Matsumoto
{"title":"Effect of tenidap on MMP-1 formation in nifedipine-reactive human gingival fibroblasts","authors":"Kosuke Hakozaki, H. Matsumoto","doi":"10.11263/JSOTP1982.27.53","DOIUrl":"https://doi.org/10.11263/JSOTP1982.27.53","url":null,"abstract":"","PeriodicalId":19590,"journal":{"name":"Oral Therapeutics and Pharmacology","volume":"27 1","pages":"53-61"},"PeriodicalIF":0.0,"publicationDate":"2008-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63820685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：