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Epilepsy Treatment Outcome and Its Predictors Among Children Who Had Chronic Follow Up at Dessie Comprehensive Specialized Hospital. 德西综合专科医院长期随访儿童的癫痫治疗结果及其预测因素。
IF 2.1 Pub Date : 2024-02-22 eCollection Date: 2024-01-01 DOI: 10.2147/PROM.S431242
Tilahun Dessie Alene, Getacher Tessema Engidaye, Tesfaye Birhane, Sisay Gedamu

Introduction: Epilepsy is a chronic non-communicable disease of the brain that affects millions of people worldwide. A significant number of children are affected globally, and most live in developing countries, often with physical and cognitive disabilities. Regardless of these factors, epilepsy is poorly controlled, particularly in the developing countries. Thus, this study aimed to assess the magnitude of treatment outcomes and its predictors among pediatrics patients with epilepsy who were followed-up at the Dessie Comprehensive Specialized Hospital, Northeast Ethiopia.

Methods: Hospital-based cross-sectional study was conducted from 1 June 2022 to 30 August 2022. A total of 200 patients with epilepsy were included in this study. Data were collected through face-to-face interviews, and by reviewing medical records. The collected data were entered into Epi-data version 4.6 and exported to SPSS version 25.0. Descriptive statistics such as frequencies, percentages, means and standard deviations were computed. Binary and multivariate logistic regression analyses were performed. Variables with p < 0.25 in bivariate analysis were entered into multivariable logistic regression. In multivariable analysis, adjusted odd ratio with 95% CI and p-value less than 0.05 were considered statistically significant.

Results: Of 200 pediatric patients with epilepsy, 66 (34.5%) had poor treatment outcomes. In the multivariate analysis, 11-15 years of age (AOR = 4.08; 95% CI = 1.202, 13.848), poor treatment adherence (AOR = 3.21; 95% CI = 1.421, 7.249), history of more seizure frequency before starting treatment (AOR = 4.19; 95% CI = 1.984, 8.834) and history of head injury (AOR = 3.03; 95% CI = 1.502, 6.112) were significantly associated with poor treatment outcomes in pediatric patients with epilepsy.

Conclusion: Significant proportion of pediatric patients with epilepsy had poor treatment outcomes. Therefore, health-care workers should strictly follow patient treatment especially for pediatric epileptic patients' who have poor treatment adherence, more seizure frequency history, head injury history and whose age were 11-15 years old.

导言:癫痫是一种慢性非传染性脑部疾病,影响着全球数百万人。全球有大量儿童受到影响,其中大多数生活在发展中国家,他们通常有身体和认知障碍。尽管存在这些因素,但癫痫的控制率却很低,尤其是在发展中国家。因此,本研究旨在评估在埃塞俄比亚东北部德西综合专科医院接受随访的儿科癫痫患者的治疗效果及其预测因素。本研究共纳入 200 名癫痫患者。通过面对面访谈和查阅病历收集数据。收集的数据输入 Epi-data 4.6 版,并导出到 SPSS 25.0 版。对频率、百分比、平均值和标准差等描述性统计进行了计算。进行了二元和多元逻辑回归分析。双变量分析中 p < 0.25 的变量被纳入多变量逻辑回归分析。在多变量分析中,调整后的奇数比(95% CI)和 p 值小于 0.05 均被认为具有统计学意义:在200名儿童癫痫患者中,66人(34.5%)的治疗效果不佳。在多变量分析中,11-15 岁(AOR = 4.08;95% CI = 1.202,13.848)、治疗依从性差(AOR = 3.21;95% CI = 1.421,7.249)、开始治疗前癫痫发作频率较高(AOR = 4.19;95% CI = 1.984,8.834)和头部受伤史(AOR = 3.03;95% CI = 1.502,6.112)与儿科癫痫患者治疗效果不佳显著相关:结论:相当一部分儿科癫痫患者的治疗效果不佳。因此,医护人员应严格遵循患者的治疗方案,尤其是对治疗依从性差、发作频率高、有头部外伤史、年龄在11-15岁之间的小儿癫痫患者。
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引用次数: 0
Development and Content Validation of Novel Patient-Reported Outcome Measures to Assess Disease Severity and Change in Patients with Erythropoietic Protoporphyria: The EPP Impact Questionnaire (EPIQ) 用于评估促红细胞生成原卟啉症患者疾病严重程度和变化的新型患者报告结果测量方法的开发和内容验证:促红细胞生成素卟啉症影响问卷 (EPIQ)
IF 2.1 Pub Date : 2024-02-01 DOI: 10.2147/prom.s438892
Susan Mathias, Laurie Burke, Hilary Colwell, George Mensing, Will Savage, H. Naik
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引用次数: 0
Cross-Sectional Quantitative Evaluation of a Novel Patient-Reported Outcome Measure in Familial Chylomicronemia Syndrome 对家族性乳糜微粒血症综合征新型患者报告结果测量方法的横断面定量评估
IF 2.1 Pub Date : 2024-02-01 DOI: 10.2147/prom.s441583
T. Brown, Montserrat Vera-Llonch, Chisom Kanu, A. Sikora Kessler, Aaron Yarlas, Sheri Fehnel
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引用次数: 0
Incidence and Predictors of Cardiac Arrest Among Patients Admitted to the Intensive Care Units of a Comprehensive Specialized Hospital in Central Ethiopia 埃塞俄比亚中部一家综合专科医院重症监护室收治的患者中心脏骤停的发生率和预测因素
IF 2.1 Pub Date : 2024-02-01 DOI: 10.2147/prom.s452338
Taye Ashine, A. Heliso, G. Babore, Elias Ezo, Sentayehu Saliya, Bethelhem Muluneh, Michael Alaro, Tadesse Adeba, Sisay Sebro, Awoke Hailu, Elias Abdisa
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引用次数: 0
Incidence and Predictors of Cardiac Arrest Among Patients Admitted to the Intensive Care Units of a Comprehensive Specialized Hospital in Central Ethiopia 埃塞俄比亚中部一家综合专科医院重症监护室收治的患者中心脏骤停的发生率和预测因素
IF 2.1 Pub Date : 2024-02-01 DOI: 10.2147/prom.s452338
Taye Ashine, A. Heliso, G. Babore, Elias Ezo, Sentayehu Saliya, Bethelhem Muluneh, Michael Alaro, Tadesse Adeba, Sisay Sebro, Awoke Hailu, Elias Abdisa
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引用次数: 0
Development and Content Validation of Novel Patient-Reported Outcome Measures to Assess Disease Severity and Change in Patients with Erythropoietic Protoporphyria: The EPP Impact Questionnaire (EPIQ) 用于评估促红细胞生成原卟啉症患者疾病严重程度和变化的新型患者报告结果测量方法的开发和内容验证:促红细胞生成素卟啉症影响问卷 (EPIQ)
IF 2.1 Pub Date : 2024-02-01 DOI: 10.2147/prom.s438892
Susan Mathias, Laurie Burke, Hilary Colwell, George Mensing, Will Savage, H. Naik
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引用次数: 0
Cross-Sectional Quantitative Evaluation of a Novel Patient-Reported Outcome Measure in Familial Chylomicronemia Syndrome 对家族性乳糜微粒血症综合征新型患者报告结果测量方法的横断面定量评估
IF 2.1 Pub Date : 2024-02-01 DOI: 10.2147/prom.s441583
T. Brown, Montserrat Vera-Llonch, Chisom Kanu, A. Sikora Kessler, Aaron Yarlas, Sheri Fehnel
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引用次数: 0
Usage and Health Outcomes of Home Hemodialysis vs Center Hemodialysis in Racial/Ethnic Minority Groups in the United States a Quantitative Research in 2016–2019 USRDS Using Aday-Anderson Framework and Multiple Regression Models 使用 Aday-Anderson 框架和多元回归模型对 2016-2019 年 USRDS 中美国少数种族/族裔群体家庭血液透析与中心血液透析的使用情况和健康结果进行定量研究
IF 2.1 Pub Date : 2024-01-01 DOI: 10.2147/prom.s416279
Ying Zhu
Introduction Home hemodialysis (HHD) offers patients with end-stage kidney disease (ESKD) greater flexibility and advantages of health outcomes over center hemodialysis (CHD). This study aims to investigate the differences between home and center hemodialysis with a focus on racial/ethnic minorities. Methods The US Renal Disease System (USRDS) 2019 patient core data containing mortality and hospitalization which are cumulative since 2010 were merged with 2016–2019 Medicare clinical claims. To assess demographic and medical factors adjusted utilization and mortality of HHD vs CHD within every racial/ethnic cohort, logistic regression was used, and negative binomial regression was conducted to analyze the number of hospitalizations. Results Evaluating 548,453 (97.48%) CHD patients and 14,202 (2.52%) HHD patients with Whites 47%, Blacks 32%, Hispanics 15%, Asians 4%, and other minorities 2%, the outcomes from adjusted regressions showed that: 1) minorities were significantly less likely to use HHD than Whites (Blacks: OR, 0.568, 95% CI, 0.546–0.592; Hispanics: OR, 0.510, 95% CI, 0.477–0.544; Asians: OR, 0.689, 95% CI, 0.619–0.766; Others: OR, 0.453, 95% CI, 0.390–0.525; p < 0.001); 2) most minority patients were younger and had fewer comorbidities than Whites, and all minority groups displayed significantly lower mortality and hospitalization incidences than the White group with adjustment on multiple covariates; 3) in the overall and main racial/ethnic cohorts, HHD showed a significantly lower risk of death than CHD after confounding for major risk factors (overall cohort: OR, 0.686, 95% CI, 0.641–0.734; White: OR, 0.670, 95% CI, 0.612–0.734; Blacks: OR, 0.717, 95% CI, 0.644–0.799; Hispanics: OR, 0.715, 95% CI, 0.575–0.889; Others: OR, 0.473, 95% CI, 0.265–0.844). Conclusion There are substantial racial/ethnic variations in home hemodialysis use and health outcomes in the United States.
导言:与中心血液透析(CHD)相比,家庭血液透析(HHD)为终末期肾病(ESKD)患者提供了更大的灵活性和更佳的健康效果。本研究旨在调查家庭血液透析与中心血液透析之间的差异,重点关注少数种族/民族。方法 将美国肾脏疾病系统(USRDS)2019 年患者核心数据(包含自 2010 年以来累积的死亡率和住院情况)与 2016-2019 年医疗保险临床索赔合并。为了评估人口和医疗因素对每个种族/族裔队列中 HHD vs CHD 使用率和死亡率的影响,采用了逻辑回归,并对住院次数进行了负二项回归分析。结果 对 548,453 名(97.48%)心脏病患者和 14,202 名(2.52%)高血压患者进行了评估,其中白人占 47%,黑人占 32%,西班牙裔占 15%,亚裔占 4%,其他少数族裔占 2%:1) 少数民族使用 HHD 的可能性明显低于白人(黑人:OR, 0.568, 95%):OR,0.568,95% CI,0.546-0.592;西班牙裔:OR,0.510,95% CI,0.477-0.544;亚洲人:OR,0.689,95% CI,0.619-0.766;其他:OR,0.453,95% CI,0.390-0.525;P < 0.001);2)与白人相比,大多数少数族裔患者更年轻,合并症更少,在对多个协变量进行调整后,所有少数族裔群体的死亡率和住院发生率均显著低于白人群体;3)在总体队列和主要种族/族裔队列中,在对主要风险因素进行混淆后,HHD 的死亡风险显著低于 CHD(总体队列:OR,0.686,95% CI,0.641-0.734;白人:OR,0.670,95% CI,0.641-0.734;其他:OR,0.686,95% CI,0.641-0.525;P < 0:OR,0.670,95% CI,0.612-0.734;黑人:OR,0.717,95% CI,0.644-0.799;西班牙裔:OR,0.715,95% CI,0.575-0.889;其他:OR,0.473,95% CI,0.265-0.844)。结论 在美国,家庭血液透析的使用和健康结果存在很大的种族/民族差异。
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引用次数: 0
Exploring Effective Communication Strategies Employed by Physicians in Delivering Bad News in Ethiopian State Hospitals. 探索埃塞俄比亚国立医院医生在传递坏消息时采用的有效沟通策略。
IF 2.1 Pub Date : 2023-12-20 eCollection Date: 2023-01-01 DOI: 10.2147/PROM.S390164
Alebel Guangul Gessesse, Jemal Mohammed Haile, Amanuel Gebru Woldearegay

Introduction: Delivering Bad News (DBN) presents a highly challenging situation in physician-patient communication. This study aims to gain insight into the various communication strategies employed by physicians when DBN.

Methods: This qualitative study conducted thematic analysis of in-depth interviews. Physicians from two comprehensive hospitals with large patient populations were selected purposively based on their engagement in delivering bad news to patients. Thematic analysis was made.

Results: Thematic analysis of the data revealed several communication strategies physicians use when delivering bad news. These communication strategies include. Jointly Initiated Physician-Patient Communication Strategies: ((i) Discussing with patient family/caregivers, (ii) Collaborating with other physicians and specialists), Patient-Engaged/Led Communication Strategies: ((iii) Investigating with adolescents alone or without the family, (iv) Helping patients predict what the news is, (v) Identifying patients' emotions related to bad news, (vi) Assessing patients' level of understanding, (vii) Minimizing patient anxiety), Physician-Related Communication Strategies: ((viii) Making sure diagnostic results are accurate, (xi) Identifying causes for rejection, (x) deliveringbad news using clear and simple communication).

Conclusion: Delivering bad news to patients can be challenging for physicians. It is important to be clear and accurate, and to prepare patients for the news. Patients may feel more comfortable and open when they are unaccompanied and with their healthcare provider. The study concluded that physicians need to be prepared to deliver bad news in a sensitive and effective manner.

导言:传递坏消息(DBN)是医患沟通中极具挑战性的情况。本研究旨在深入了解医生在传递坏消息时所采用的各种沟通策略:这项定性研究对深度访谈进行了专题分析。根据医生向患者传达坏消息的参与情况,有目的性地选择了两家拥有大量患者的综合性医院的医生进行访谈。研究对数据进行了主题分析:对数据的主题分析表明,医生在传达坏消息时使用了几种沟通策略。这些沟通策略包括医患共同发起的沟通策略:((i) 与患者家属/护理人员讨论;(ii) 与其他医生和专家合作);患者参与/主导的沟通策略:((iii)与青少年单独或在没有家属陪同的情况下进行调查;(iv)帮助患者预测消息的内容;(v)确定患者与坏消息相关的情绪;(vi)评估患者的理解程度;(vii)最大限度地减少患者的焦虑);与医生相关的沟通策略:((viii)确保诊断结果准确无误;(xi)确定排斥的原因;(x)使用清晰简单的沟通方式传达坏消息)。结论:对医生来说,向患者传达坏消息是一项挑战。重要的是要清晰、准确,并让患者对这一消息有所准备。当患者在无人陪伴的情况下与他们的医疗服务提供者在一起时,他们可能会感觉更加舒适和坦诚。研究认为,医生需要做好准备,以敏感和有效的方式传达坏消息。
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引用次数: 0
Lived Experiences of Patients on Hemodialysis Treatment at Kiruddu National Referral Hospital: A Phenomenological Study. 基鲁杜国家转诊医院血液透析患者的生活经历:现象学研究。
IF 2.1 Pub Date : 2023-12-13 eCollection Date: 2023-01-01 DOI: 10.2147/PROM.S431746
Alobo Jennifer Ogwang, Eric Baluku Murungi, Niyonzima Vallence, Beebwa Esther

Background: There is increasing number of patients undergoing hemodialysis globally. Patients on hemodialysis experience physical and emotional stress due to the changes brought by chronic kidney disease.

Aim: The study aimed at exploring the lived experiences of patients on hemodialysis treatment in Kiruddu National Referral Hospital.

Methods: The study employed a phenomenological design. Data was collected using audio tape recording of the interview from 9 participants selected through purposive sampling at Kiruddu National Referral Hospital. The thematic aspects of the lived experience were uncovered using Van Manen data analysis which included three approaches: the detailed or line-by-line approach, selective or highlighting approach and holistic approach.

Results: Six themes emerged during the analysis as hemodialysis prolongs survival; hemodialysis is indispensable, family financial support, physical limitations, emotional distress and adaptation.

Conclusion: It was concluded from the findings that the patients undergoing haemodialysis are facing a wide range of problems such as physical and emotional problems during the course of their treatment and think that haemodialysis is the only way of survival, and these problems need to be addressed. Understanding gained in this study can help nurses to utilize this information in improving the quality of nursing care and guide patients to provide positive reinforcement for their future living.

背景:全球接受血液透析治疗的患者人数不断增加。由于慢性肾病带来的变化,血液透析患者在身体和情绪上都承受着压力。目的:本研究旨在探讨基鲁杜国家转诊医院血液透析患者的生活经历:研究采用现象学设计。研究采用了现象学设计,在基鲁杜国家转诊医院通过目的性抽样从 9 名参与者中收集了访谈录音资料。范曼恩数据分析包括三种方法:详细或逐行分析法、选择性或突出分析法和整体分析法:分析过程中出现了六个主题:血液透析延长生存期、血液透析不可或缺、家庭经济支持、身体限制、情绪困扰和适应:结论:研究结果表明,接受血液透析的患者在治疗过程中面临着身体和情绪等多方面的问题,他们认为血液透析是唯一的生存方式,这些问题需要得到解决。本研究获得的信息有助于护士利用这些信息提高护理质量,引导患者为今后的生活提供积极的鼓励。
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引用次数: 0
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Patient Related Outcome Measures
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