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Effects of exercise interventions on memory in depression: a three-level meta-analysis. 运动干预对抑郁症患者记忆的影响:一个三水平荟萃分析。
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-05 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20750
Xiaoling Zhu, Yunong Zhang, Cong Liu, Xing Wang

Background: Patients with depression have memory impairment. Exercise can improve memory in people with depression. This study employs a three-level meta-analysis to investigate the interventional effects of exercise on verbal and visual memory in patients with depression.

Methods: A systematic electronic search was conducted in China National Knowledge Infrastructure, Wanfang Data, China Biomedicine, PubMed, EMBASE, the Cochrane Library, and Web of Science to identify randomized controlled trials investigating the effects of exercise interventions on memory in individuals with depression, up to July 18, 2024. A three-level meta-analysis based on a random-effects model was performed using R. The risk of bias of the included studies was assessed using the Cochrane Risk of Bias 2 (RoB 2) tool.

Results: A total of 16 studies were included in the analysis. The results indicated a statistically significant but small effect of exercise on verbal memory in patients with depression (g = 0.17, 95% confidence interval (CI) [0.02-0.32], p = 0.03); however, the 95% prediction interval crossed zero, suggesting that the effect may not be consistent across different settings or future studies; however, the 95% prediction interval crossed zero, suggesting that the effect may not be consistent across different settings or future studies (g = 0.27, 95% CI [-0.00-0.54], p = 0.05). Exercise intensity significantly moderated the effect of exercise on verbal memory in patients with depression (F = 3.39, p = 0.04), whereas exercise type, session time, duration, age, and intervention content of the experimental group were not moderating factors (p > 0.05). Low-to-moderate intensity (g = 0.43, p < 0.01), duration ≤12 weeks (g = 0.27, p < 0.01), and session time ≤60 minutes (g = 0.18, p = 0.03) of mind-body exercise (g = 0.43, p < 0.01) were most likely to improve verbal memory in patients with depression. The level of evidence was "moderate".

Conclusions: Exercise may confer a small improvement in verbal memory among adults with depression, while no clear effect was observed for visual memory. However, further randomized controlled trials are needed to explore the impact of exercise on memory in patients with depression. Research plan was registered in international system evaluation platform PROSPERO (https://www.crd.york.ac.uk/PROSPERO/) (CRD42023473393).

背景:抑郁症患者存在记忆障碍。运动可以改善抑郁症患者的记忆力。本研究采用三水平荟萃分析,探讨运动对抑郁症患者语言和视觉记忆的干预作用。方法:系统电子检索中国国家知识基础设施、万方数据、中国生物医学、PubMed、EMBASE、Cochrane图书馆和Web of Science,以确定截至2024年7月18日的随机对照试验,研究运动干预对抑郁症患者记忆的影响。采用r进行基于随机效应模型的三水平荟萃分析。采用Cochrane risk of bias 2 (RoB 2)工具评估纳入研究的偏倚风险。结果:共纳入16项研究。结果显示,运动对抑郁症患者言语记忆的影响有统计学意义,但很小(g = 0.17, 95%可信区间(CI) [0.02-0.32], p = 0.03);然而,95%的预测区间过零,表明在不同的环境或未来的研究中,效果可能不一致;然而,95%的预测区间过零,表明在不同的环境或未来的研究中,效果可能不一致(g = 0.27, 95% CI [-0.00-0.54], p = 0.05)。运动强度显著调节运动对抑郁症患者言语记忆的影响(F = 3.39, p = 0.04),实验组的运动类型、运动时间、持续时间、年龄和干预内容均不是调节因素(p < 0.05)。低至中等强度(g = 0.43, p g = 0.27, p g = 0.18, p = 0.03)身心运动(g = 0.43, p)结论:运动可能对成年抑郁症患者的言语记忆有轻微的改善,而对视觉记忆没有明显的影响。然而,需要进一步的随机对照试验来探索运动对抑郁症患者记忆的影响。研究计划已在国际系统评价平台PROSPERO (https://www.crd.york.ac.uk/PROSPERO/)注册(CRD42023473393)。
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引用次数: 0
Acute toxicity of TNT derivatives and hydrazine-based compounds from explosive and rocket fuel contamination to darkling beetles (Tenebrio molitor and Opatrum sabulosum). 炸药和火箭燃料污染的TNT衍生物和肼基化合物对黑甲虫的急性毒性。
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-05 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20427
Denis F Rybalka, Viktor V Brygadyrenko

The problem of toxic pollution of the environment by combustion products of explosives and rocket fuel is becoming increasingly important in the context of intensified military operations. In this study, the toxicity of TNT derivatives, hydrazine-based compounds, and nitroaromatic transformation products related to explosive and rocket fuel contamination was evaluated using the model organisms Tenebrio molitor Linnaeus, 1758 and Opatrum sabulosum (Linnaeus, 1761). We chose hydrazine derivatives, nitroanilines, benzene and naphthalene-based nitro compounds that can persist in the ground, water and atmosphere after explosions or incomplete combustion of rocket fuel. Topical dispersion was used to evaluate exposure of specified doses on the surface of containers containing larvae and imagoes of T. molitor and imagoes of O. sabulosum, followed by lethality counts and LC50 determination. The results indicate the high sensitivity of T. molitor larvae and imagoes and O. sabulosum imagoes to TNT derivatives, hydrazine compounds, and nitroaromatic contaminants commonly found in explosive-contaminated environments, which confirms the feasibility of introducing ecotoxicological monitoring of military-technological impact zones. The systematic toxicity assessment of these 29 explosive-related compounds provides essential baseline data for environmental risk modeling and ecotoxicological monitoring programs. The data obtained can be used for further modeling of environmental risk and development of bioindicator approaches to detect pollution as a result of military operations, for example, in Ukraine.

在军事行动加剧的情况下,爆炸物和火箭燃料燃烧产物对环境造成有毒污染的问题变得越来越重要。在本研究中,使用模式生物tenbrio molitor Linnaeus(1758)和Opatrum sabulosum (Linnaeus, 1761)对TNT衍生物、肼基化合物和硝基芳香转化产物与炸药和火箭燃料污染相关的毒性进行了评估。我们选择了肼衍生物、硝基苯胺、苯和萘基硝基化合物,这些化合物在爆炸或火箭燃料不完全燃烧后可以在地面、水和大气中持续存在。采用局部分散法,评价特定剂量暴露于装恙虫幼虫、恙虫像和大鼠像的容器表面,然后进行致死计数和LC50测定。结果表明t·莫利托高灵敏度的幼虫和成虫和o . sabulosum成TNT衍生品,肼化合物,和硝基芳香化合物污染物explosive-contaminated环境中普遍存在,这证实了引入的可行性ecotoxicological监测区域军事科技的影响。对这29种爆炸物相关化合物的系统毒性评估为环境风险建模和生态毒理学监测项目提供了必要的基线数据。所获得的数据可用于进一步模拟环境风险和开发生物指标方法,以检测军事行动(例如在乌克兰)造成的污染。
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引用次数: 0
Effects of playing experience on joint kinetics and ball-release velocity in mid- and long-range basketball jump shots. 打球经验对中远跳投关节动力学和投球释放速度的影响。
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-05 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20757
Pengzhou Chen, Tao Chen, Xuan Tang, Ming Li, Xiangjun Miao

Purpose: This study investigated how playing experience influences joint kinetics and ball-release velocity during mid- and long-range jump shots. Wrist, elbow, shoulder and knee rate of torque development (RTD), peak power (Ppeak), and angular impulse (AI) were quantified, along with vertical release velocity (VV) and horizontal release velocity (HV) at release.

Methods: In a cross-sectional design, 15 experienced and 15 novice male collegiate basketball players each performed three made jump shots from 4.8 m and 6.75 m. A 3-D motion-capture system synchronised with force plates provided the data used to compute RTD, Ppeak, AI, VV and HV. Outcomes were compared with a two-way mixed ANOVA.

Results: Experienced players exhibited greater wrist AI (p < 0.001), elbow RTD (p = 0.002), Ppeak (p = 0.045) and AI (p < 0.001), knee Ppeak (p = 0.002) and VV (p < 0.001). Longer shooting distance increased shoulder Ppeak (p = 0.036) and HV (p = 0.018).

Conclusions: Collectively, these results show that experience enhances joint kinetic output, providing the mechanical foundation for more efficient and dependable shooting. For novice players, emphasising wrist-endurance work, explosive-power training for the elbow and knee, and targeted drills to raise VV is recommended to improve overall on-court shooting performance.

目的:本研究探讨打球经验对中远跳投中关节动力学和球释放速度的影响。量化腕、肘、肩和膝关节的扭矩发展速率(RTD)、峰值功率(Ppeak)和角冲量(AI),以及释放时的垂直释放速度(VV)和水平释放速度(HV)。方法:采用横断面设计,选取15名经验丰富的大学男篮球运动员和15名新手,分别在4.8米和6.75米高度进行3次跳投。与测力板同步的三维动作捕捉系统提供了用于计算RTD、峰值、AI、VV和HV的数据。结果比较采用双向混合方差分析。结果:经验丰富的运动员手腕AI (p = 0.002)、Ppeak (p = 0.045)、AI (p峰(p = 0.002)、VV (p峰(p = 0.036)、HV (p = 0.018)较大。结论:总的来说,这些结果表明,经验增强了关节的动力输出,为更有效和可靠的射击提供了机械基础。对于新手,建议加强腕部耐力训练,肘部和膝盖的爆发力训练,以及有针对性的提高VV的训练,以提高球场上的整体投篮表现。
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引用次数: 0
Divergent response of soil microbial community abundance and composition to fertilization in Camellia oleifera plantation, Southern China. 南方油茶人工林土壤微生物群落丰度和组成对施肥的差异性响应
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-05 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20741
Hanfang Luo, Li Wen, Chao Li, Kaikai Cheng, Lihong Shi, Ke Wang, Haiming Tang

Introduction: Alterations in the composition and structure of the soil microbial community exert a substantial impact on soil nutrient cycling and fertility. Implementing sustainable land use strategies involves a deeper comprehension of the dynamics of the soil microbial community under different fertilization approaches.

Methods: Phospholipid fatty acid (PLFA) method was employed to characterize soil microbial community abundance and structure under four fertilization treatments (no fertilizer (CK), 100% mineral fertilizer (NPK), 30% organic fertilizer + 70% mineral fertilizer (LOM), and 60% organic fertilizer + 40% mineral fertilizer (HOM)) in a Camellia oleifera plantation area in southern China.

Results: Fertilization application substantially increased the Camellia oleifera yields, with the highest increment observed under the HOM treatment. Soil organic carbon and total nitrogen levels were significantly increased in LOM and HOM treatments as compared to CK. Total PLFAs absolute abundance in LOM and HOM treatments increased by 68.45% and 85.38%, respectively, compared to CK treatment. Furthermore, the absolute abundances of bacteria, fungi, and actinomycetes, as well as total PLFAs, were markedly enhanced in HOM and LOM treatments but not in the NPK treatment relative to CK treatment. There was less distinction observed in the microbial community structure than in microbial abundance across four fertilization treatments. Soil nutrients were identified as the primary factor affecting soil microbial abundance and crop yield. These findings imply that the combined application of organic and mineral fertilization than employing solely mineral fertilization may be more effective in improving soil nutrient levels, regulating soil microbial community composition and increasing crop yield in a Camellia oleifera plantation.

导读:土壤微生物群落组成和结构的变化对土壤养分循环和肥力有重要影响。实施可持续土地利用战略需要更深入地了解不同施肥方式下土壤微生物群落的动态。方法:采用磷脂脂肪酸(PLFA)法对中国南方油茶种植区4种施肥处理(无肥(CK)、100%矿物肥(NPK)、30%有机肥+ 70%矿物肥(LOM)、60%有机肥+ 40%矿物肥(HOM))下土壤微生物群落的丰度和结构进行了表征。结果:施肥显著提高了油茶产量,其中以土肥处理的增产幅度最大。土壤有机碳和全氮水平显著高于对照。与对照相比,LOM和HOM处理的PLFAs总绝对丰度分别提高了68.45%和85.38%。此外,相对于CK, HOM和LOM处理显著提高了细菌、真菌和放线菌的绝对丰度,以及总PLFAs,但NPK处理没有显著提高。在4个施肥处理中,微生物群落结构的差异小于微生物丰度的差异。土壤养分是影响土壤微生物丰度和作物产量的主要因素。综上所述,有机肥与矿肥配施在改善油茶人工林土壤养分水平、调节土壤微生物群落组成和提高作物产量方面可能比单施矿肥更有效。
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引用次数: 0
Integrating agro-physiological traits and yield performance in soybean (Glycine max L.) resistance to fall armyworm (Spodoptera frugiperda) through genotype analysis. 通过基因型分析综合大豆(Glycine max L.)抗秋粘虫的农业生理性状和产量表现。
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20753
Anna Satyana Karyawati, Demas Dharmawan, Himma Rahmadillah, Budi Waluyo, Vina Mafazatul Ula

Fall armyworm (Spodoptera frugiperda) is a major invasive pest threatening soybean production, and identifying resistant genotypes is essential for sustainable crop protection. This study evaluated 36 soybean genotypes for their resistance to S. frugiperda based on leaf damage intensity and frequency, resistance classification, morphophysiological traits, and yield components. The research was conducted under field conditions using a randomized complete block design (RCBD) with three replications. Armyworm damage was assessed at 36 and 41 days after planting (DAP), and all quantitative data were analyzed using ANOVA followed by the Scott-Knott test at a 5% significance level. Data were presented as mean ± standard deviation (SD). Significant variation was evident among genotypes, with attack intensity at 41 DAP ranging from 18.31 ± 10.64% to 61.20 ± 11.39%, and attack frequency from 33.38 ± 16.92% to 95.49 ± 5.35%. Based on mean intensity values, one genotype was categorized as strongly resistant (SR) (UB 2), four as resistant (R) (UBASK24, UBASK35, GBG, TGM), and a broader set as moderately resistant (MR), while highly susceptible (HS) genotypes included UBASK15, UBASK62, UBASK64, UBASK32, UBASK36, and UBASK14. Morphophysiological traits exhibited wide variation, including leaf trichome density (13.56-42.11 trichomes 0.25 cm-2), plant height (38.42-78.67 cm), and flowering time (31-47 DAP), while yield traits identified TGM, UBASK35, UBASK24, and GBG as the highest-performing genotypes. Overall, UB 2, UBASK24, UBASK35, GBG, and TGM are promising parental candidates for breeding soybean resistance against S. frugiperda, integrating strong resistance expression with favorable agronomic performance.

秋粘虫(Spodoptera frugiperda)是威胁大豆生产的主要入侵害虫,鉴定抗性基因型对作物可持续保护至关重要。从叶片危害强度和发生频率、抗性分类、形态生理性状和产量组成等方面对36个大豆基因型进行了抗性评价。研究采用随机完全区组设计(RCBD),在野外条件下进行,有3个重复。在种植后36和41 d (DAP)评估粘虫危害,所有定量数据采用方差分析,然后进行5%显著性水平的Scott-Knott检验。数据以均数±标准差(SD)表示。基因型间差异显著,41 DAP的攻击强度在18.31±10.64% ~ 61.20±11.39%之间,攻击频率在33.38±16.92% ~ 95.49±5.35%之间。根据平均强度值,1个基因型被分类为强耐药(SR) (UB 2), 4个基因型(R) (UBASK24, UBASK35, GBG, TGM),以及更广泛的中度耐药(MR),而高度敏感(HS)基因型包括UBASK15, UBASK62, UBASK64, UBASK32, UBASK36和UBASK14。叶片毛状体密度(13.56 ~ 42.11毛状体,0.25 cm-2)、株高(38.42 ~ 78.67 cm)、开花时间(31 ~ 47 DAP)等形态生理性状差异较大,而产量性状中表现最好的基因型为TGM、UBASK35、UBASK24和GBG。综上所述,ub2、UBASK24、UBASK35、GBG和TGM是具有较强抗性表达和良好农艺性能的大豆抗性亲本。
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引用次数: 0
Admission serum tropomyosin 4 levels predict 1-year functional outcomes in acute ischemic stroke. 入院血清原肌球蛋白4水平预测急性缺血性脑卒中1年功能结局。
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20745
Keying Wu, Mingxi Chen, Huan Wang, Yuyi Zhu, Yaqi Chen, Shihong Zhang, Xinyi Leng, Zilong Hao, Deren Wang

Background: Tropomyosin 4 (TPM4) regulates neurite outgrowth and vascular pathology but its role as a biomarker for predicting outcomes in stroke patients is unclear. This study investigated the association between serum TPM4 levels and 1-year functional outcomes in acute ischemic stroke (AIS) patients.

Methods: AIS patients admitted within 24 h post-onset from the Chengdu Stroke Registry were included. Serum TPM4 levels were measured by enzyme-linked immunosorbent assay (ELISA). Poor functional outcomes were defined as a modified Rankin Scale (mRS) score >2 at 1 year after stroke onset. Multivariate logistic regression assessed TPM4's association with outcomes, with its predictive incremental value evaluated by discrimination, reclassification, and overall performance metrics.

Results: Among 181 patients (median age 66 years, 64.1% male), 59 (32.6%) experienced poor outcomes at 1 year, including 16 deaths (8.8%). Serum TPM4 levels on admission were negatively correlated with the National Institutes of Health Stroke Scale (NIHSS) score (r = -0.185, p = 0.013). Adjusted for confounders, lower serum TPM4 levels were independently associated with 1-year poor functional outcomes (adjusted OR 0.045, 95% CI [0.005-0.393], p = 0.005). Serum TPM4 levels had acceptable discriminative ability for predicting poor outcomes (AUROC 0.706, 95% CI [0.621-0.791], p < 0.0001). Incorporating TPM4 into the basic model significantly improved the predictive power for poor functional outcomes (net reclassification index: 31.87%, p = 0.041; integrated discrimination improvement: 5.01%, p = 0.008; Brier score decreased from 0.16 to 0.15, p = 0.012).

Conclusions: Lower serum TPM4 levels on admission were independently associated with poor functional outcomes at 1 year in AIS patients, suggesting that TPM4 may serve as a potential biomarker for long-term outcomes and offer insights into its potential role in stroke pathophysiology. These findings need to be further verified in external cohorts.

背景:原肌球蛋白4 (TPM4)调节神经突生长和血管病理,但其作为预测脑卒中患者预后的生物标志物的作用尚不清楚。本研究探讨了急性缺血性卒中(AIS)患者血清TPM4水平与1年功能结局之间的关系。方法:纳入成都市卒中登记中心发病后24小时内入院的AIS患者。采用酶联免疫吸附试验(ELISA)检测血清TPM4水平。脑卒中发作后1年,功能不良的定义为改良的Rankin量表(mRS)评分为bb0.2。多变量逻辑回归评估TPM4与预后的关系,并通过区分、重新分类和总体表现指标评估其预测增量值。结果:181例患者(中位年龄66岁,男性64.1%),59例(32.6%)1年预后不良,包括16例死亡(8.8%)。入院时血清TPM4水平与NIHSS评分呈负相关(r = -0.185, p = 0.013)。经混杂因素校正后,较低的血清TPM4水平与1年功能不良预后独立相关(校正OR 0.045, 95% CI [0.005-0.393], p = 0.005)。血清TPM4水平在预测不良预后方面具有可接受的判别能力(AUROC为0.706,95% CI [0.621-0.791], p < 0.0001)。将TPM4纳入基本模型显著提高了功能不良预后的预测能力(净重分类指数:31.87%,p = 0.041;综合判别改善:5.01%,p = 0.008; Brier评分从0.16降至0.15,p = 0.012)。结论:入院时较低的血清TPM4水平与AIS患者1年后较差的功能预后独立相关,表明TPM4可能作为长期预后的潜在生物标志物,并为其在卒中病理生理中的潜在作用提供见解。这些发现需要在外部队列中进一步验证。
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引用次数: 0
Evidence-based practice among physiotherapists in India: a nationwide survey of knowledge, attitude, and implementation behavior. 印度物理治疗师的循证实践:一项关于知识、态度和实施行为的全国性调查。
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20632
Mohammad Sidiq, Jyoti Sharma, Balamurugan Janakiraman, Faizan Kashoo, Aksh Chahal, Ruchi Varshney, Sumbul Ansari, Akriti Pandey, Richa Hirendra Rai, Abdulqader Khormi, Imran Khan, Mohammed M Alshehri, Monira I Aldhahi

Background: Physiotherapy services are often integrated within the broader healthcare system in India. Unlike in developed countries, physiotherapy is still limited to indirect access and needs a referral from other healthcare providers, which potentially limits physiotherapists. The purpose of this study was to explore the knowledge or skill, attitude, and behavior towards the implementation of evidence-based practice (EBP) in physiotherapy care. In addition, the physiotherapist's perception of barriers in the implementation of EBP was inquired.

Methods: A cross-sectional study was conducted through an online survey involving two thousand nine hundred and ninety-six physiotherapists from 22 states/union territories in India. A 24-item EBP questionnaire (EBPQ) investigating knowledge, attitude, and behavior domains with a 1 to 7 Likert scale response for each item, with a higher score indicating a favorable response. A linear regression model was used to analyze the relationship between factors and evidence-based practice behavior among physiotherapists.

Results: The mean age of the participants was 35.8 ± 6.2 years, with a work experience of 13.25 ± 6.38 years. The overall EBPQ mean score of Indian physiotherapists was 3.6 ± 0.38, and the mean scores of the domains-knowledge, attitude, and implementation of EBP-were 3.59 ± 0.53, 4.29 ± 0.79, and 3.20 ± 0.62, respectively. The EBP domains were mainly determined by the educational attainment and workplace, which explained 46.1% of the variance. Lack of time and skills was identified as the top barrier influencing EBP among physiotherapists in India. The behavior dimension score of EBPQ is determined by 8 knowledge items and 2 attitude items, which explain 61.2% of the variance.

Conclusions: The Indian physiotherapists reported a positive attitude toward evidence-based practice; however, their knowledge and behavior were observed to be insufficient. Lack of time, limited skills, a shortage of resources, and limitations in applying EBP were reported as the main barriers.

背景:在印度,物理治疗服务通常被纳入更广泛的医疗保健系统。与发达国家不同,物理治疗仍然局限于间接获取,需要其他医疗保健提供者的转诊,这可能限制了物理治疗师。本研究的目的是探讨在物理治疗护理中实施循证实践(EBP)的知识或技能、态度和行为。此外,我们还调查了物理治疗师对实施EBP障碍的看法。方法:一项横断面研究通过在线调查进行,涉及来自印度22个邦/联邦属地的2,996名物理治疗师。一个24题EBP问卷(EBPQ)调查知识、态度和行为领域,每个题的李克特反应为1到7分,得分越高表示反应越好。采用线性回归模型分析各因素与物理治疗师循证执业行为的关系。结果:参与者平均年龄为35.8±6.2岁,工作经验为13.25±6.38岁。印度物理治疗师的EBPQ总分平均得分为3.6±0.38分,ebp知识、态度和执行领域平均得分分别为3.59±0.53分、4.29±0.79分和3.20±0.62分。EBP域主要由受教育程度和工作场所决定,解释了46.1%的方差。缺乏时间和技能被确定为影响印度物理治疗师EBP的最大障碍。EBPQ的行为维度得分由8个知识项和2个态度项决定,解释了61.2%的方差。结论:印度物理治疗师对循证实践持积极态度;然而,他们的知识和行为被观察到是不足的。缺乏时间,有限的技能,资源短缺和应用EBP的限制被报道为主要障碍。
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引用次数: 0
Effects of variable resistance training on lower limb explosive power in athletes: a systematic review and meta-analysis. 可变阻力训练对运动员下肢爆发力的影响:系统回顾和荟萃分析。
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20644
Ziqi Xu, Songpeng Su, Zitong Xu

Objectives: This study aims to investigate the effects of variable resistance training (VRT) on athletes' lower limb explosive power through assessments of jumping, sprinting, and change of direction (COD) performance.

Methods: A systematic search was conducted across four electronic databases (Web of Science, PubMed, Scopus, ProQuest) from their inception until March 23, 2025. Study eligibility was assessed against the Population, Intervention, Comparison, Outcomes, Study design (PICOS) framework. Following data extraction, the methodological quality of the included studies was assessed using the Cochrane Risk of Bias tool. Data analysis was performed using Stata 15 software, with standardized mean differences (SMD) and 95% confidence intervals calculated as the pooled effect size measure.

Results: Fifteen articles involving 442 participants were included in the final analysis. The overall meta-analysis demonstrated that VRT was an effective method for enhancing athletes' jumping performance (SMD = 0.81 cm, p < 0.001), sprint performance (SMD = -1.13 s, p < 0.001), and COD performance (SMD = -1.66 s, p < 0.001). Subgroup analyses indicated significant positive effects of VRT on vertical jump (VJ: SMD = 0.31 cm, p = 0.027), squat jump (SJ: SMD = 0.94 cm, p < 0.001), countermovement jump (CMJ: SMD = 1.01 cm, p < 0.001), 5-m sprint (SMD = -1.18 s, p < 0.001), 10-m sprint (SMD = -1.18 s, p < 0.001), 30-m sprint (SMD = -1.08 s, p = 0.013), T-test (SMD = -2.01 s, p < 0.001), repeated change of direction (RCOD: SMD = -2.01 s, p < 0.001), and Illinois test (SMD = -1.85 s, p < 0.001).

Conclusion: This systematic review suggests that VRT may serve as an effective training strategy for enhancing lower-limb explosive power in athletes. However, due to significant heterogeneity among the included studies and potential publication bias, the definitive benefits of VRT require further validation through additional high-quality research.

目的:研究可变阻力训练(VRT)对运动员下肢爆发力的影响,通过对运动员跳跃、短跑和方向改变(COD)表现的评估。方法:系统检索四个电子数据库(Web of Science, PubMed, Scopus, ProQuest),从其建立到2025年3月23日。研究资格根据人群、干预、比较、结果、研究设计(PICOS)框架进行评估。资料提取后,使用Cochrane偏倚风险工具评估纳入研究的方法学质量。使用Stata 15软件进行数据分析,计算标准化平均差异(SMD)和95%置信区间作为合并效应大小度量。结果:15篇文献纳入最终分析,共纳入442名受试者。整体meta分析表明,VRT可以有效提高运动员的跳跃成绩(SMD = 0.81 cm, p p p = 0.027)、深蹲跳成绩(SJ: SMD = 0.94 cm, p p p p = 0.013)、t检验(SMD = -2.01 s, p p p)。结论:本系统综述提示VRT可以作为提高运动员下肢爆发力的有效训练策略。然而,由于纳入的研究存在显著的异质性和潜在的发表偏倚,VRT的确切益处需要通过额外的高质量研究进一步验证。
{"title":"Effects of variable resistance training on lower limb explosive power in athletes: a systematic review and meta-analysis.","authors":"Ziqi Xu, Songpeng Su, Zitong Xu","doi":"10.7717/peerj.20644","DOIUrl":"10.7717/peerj.20644","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the effects of variable resistance training (VRT) on athletes' lower limb explosive power through assessments of jumping, sprinting, and change of direction (COD) performance.</p><p><strong>Methods: </strong>A systematic search was conducted across four electronic databases (Web of Science, PubMed, Scopus, ProQuest) from their inception until March 23, 2025. Study eligibility was assessed against the Population, Intervention, Comparison, Outcomes, Study design (PICOS) framework. Following data extraction, the methodological quality of the included studies was assessed using the Cochrane Risk of Bias tool. Data analysis was performed using Stata 15 software, with standardized mean differences (SMD) and 95% confidence intervals calculated as the pooled effect size measure.</p><p><strong>Results: </strong>Fifteen articles involving 442 participants were included in the final analysis. The overall meta-analysis demonstrated that VRT was an effective method for enhancing athletes' jumping performance (SMD = 0.81 cm, <i>p</i> < 0.001), sprint performance (SMD = -1.13 s, <i>p</i> < 0.001), and COD performance (SMD = -1.66 s, <i>p</i> < 0.001). Subgroup analyses indicated significant positive effects of VRT on vertical jump (VJ: SMD = 0.31 cm, <i>p</i> = 0.027), squat jump (SJ: SMD = 0.94 cm, <i>p</i> < 0.001), countermovement jump (CMJ: SMD = 1.01 cm, <i>p</i> < 0.001), 5-m sprint (SMD = -1.18 s, <i>p</i> < 0.001), 10-m sprint (SMD = -1.18 s, <i>p</i> < 0.001), 30-m sprint (SMD = -1.08 s, <i>p</i> = 0.013), T-test (SMD = -2.01 s, <i>p</i> < 0.001), repeated change of direction (RCOD: SMD = -2.01 s, <i>p</i> < 0.001), and Illinois test (SMD = -1.85 s, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>This systematic review suggests that VRT may serve as an effective training strategy for enhancing lower-limb explosive power in athletes. However, due to significant heterogeneity among the included studies and potential publication bias, the definitive benefits of VRT require further validation through additional high-quality research.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":"14 ","pages":"e20644"},"PeriodicalIF":2.4,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12882733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and optimization of mathematical models for uniform seed placement in precision black cumin seeding under laboratory conditions. 实验室条件下小茴香精密播种均匀撒种数学模型的建立与优化。
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20755
Gulin Turkusay, Arzu Yazgi

Objectives: The objective of the study was to quantify seed flow consistency and in-row spacing accuracy when using a conveyor belt-style metering device under varying operational parameters, to develop mathematical models, and to optimize the uniformity of seed placement for black cumin seeding.

Methods: Seed flow properties and the uniformity of in-row seed distribution uniformity were evaluated through weighing tests and sticky belt methods, respectively. The uniformity of the flow was assessed using coefficient of variation (CV) values, while the in-row seed distribution uniformity was evaluated by using the variation factor (Vf) and the goodness criterion (λ). The experiments were conducted based on Central Composite Design (CCD) under laboratory conditions. The forward speed, seed rate, and seed falling angle were chosen as independent variables. The experiments were conducted at five levels of forward speed (1.01, 1.4, 2.0, 2.6, and 3.01 m s-1), five levels of seed rate (6.6, 10, 15, 20 and 23.4 kg ha-1), and five levels of seed falling angle (1.36, 15, 35, 55 and 68.64°).

Results: The polynomial functions were developed and the Vf and λ models were optimized. Optimization reduced the variation factor (Vf) to 0.53 and improved the goodness criterion (λ) to 91.67%, indicating a substantial enhancement in seed placement uniformity. For the Vf model, the optimum forward speed was found to be 1.05 m s-1, with a seed rate of 12.35 kg ha-1 and a seed falling angle of 35°; whereas for the λ model, the corresponding values were calculated 1.55 m s-1, 21.1 kg ha-1, and 28.5°, respectively. The developed models showed high predictive accuracy, with an R 2 value of 95.96% for the λ model. Based on the findings of this work, the seed rate was determined as the most important parameter for all models considered.

Conclusions: The results of the experiments also revealed that the conveyor belt metering unit could be used for the seeding process of black cumin seeds with great success, without encountering significant problems. The comparison of R 2 value of the λ and Vf models indicated that the λ model had a better variable prediction. Therefore, the optimum values from the λ model may be more useful than those from the Vf model.

目的:研究不同操作参数下传送带式计量装置的种子流一致性和行间距精度,建立数学模型,优化黑孜然播种的均匀性。方法:采用称重法和粘带法分别评价种子流动特性和排播均匀性。采用变异系数(CV)评价种子流动均匀性,采用变异因子(Vf)和优度准则(λ)评价种子行内分布均匀性。实验采用中心复合设计(CCD),在实验室条件下进行。选取前进速度、种子速率和落粒角度作为自变量。试验设置了5个前进速度水平(1.01、1.4、2.0、2.6和3.01 m s-1), 5个种子速率水平(6.6、10、15、20和23.4 kg ha-1), 5个落种角度水平(1.36、15、35、55和68.64°)。结果:建立了多项式函数,优化了Vf和λ模型。优化后,变异因子(Vf)降低至0.53,优度判据(λ)提高至91.67%,显著提高了播种均匀性。Vf模型的最佳前进速度为1.05 m s-1,种子速率为12.35 kg ha-1,落种角为35°;而λ模型的对应值分别为1.55 m s-1、21.1 kg ha-1和28.5°。所建立的模型具有较高的预测精度,λ模型的r2值为95.96%。基于这项工作的发现,种子率被确定为所有模型中最重要的参数。结论:实验结果还表明,输送带计量装置可用于黑孜然种子的播种过程,并且成功率很高,不会遇到明显的问题。λ模型和Vf模型的r2值比较表明,λ模型具有较好的变量预测效果。因此,λ模型的最优值可能比Vf模型的最优值更有用。
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引用次数: 0
Cardioprotective effect of resveratrol in myocardial ischemia/reperfusion injury and myocardial infarction: a pre-clinical meta-analysis in animal studies. 白藜芦醇对心肌缺血/再灌注损伤和心肌梗死的心脏保护作用:动物研究的临床前荟萃分析
IF 2.4 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.7717/peerj.20708
Shi-Jie Wei, Qi-Hao Guo, Xin-Yu Wei, Si-Yu Chen, Sheng Deng, Liang An, Wen-Jing Zeng, Yi-Fan Zeng

This meta-analysis aimed to assess the cardioprotective effect of resveratrol (RES) against myocardial ischemia/reperfusion injury (MIRI) and myocardial infarction (MI) in the animal. PubMed, Web of Science, and EMBASE were searched. Primary outcomes included myocardial infarct size (IS) and cardiac function. Secondary outcomes included cardiac injury enzyme, oxidative stress level, inflammatory cytokine, and apoptosis rate. Subgroup analysis, publication bias, sensitivity analysis, meta-regression, and dosage-efficacy analysis were used to evaluate the risk of bias. Fifty-seven studies were included involving 1,125 animals. The results showed that RES treatment decreased IS in animal models of MIRI (SMD: -5.44; 95% CI [-6.42 to -4.45]; P < 0.01; I2 = 86%) and MI (SMD: -3.41; 95% CI [-4.44 to -2.38]; P < 0.01; I2 = 75%). Moreover, RES treatment improved cardiac function, decreased cardiac injury enzymes, down-regulated oxidative stress levels, alleviated inflammatory cytokine levels, and reduced apoptosis rate in animal models of MIRI and MI. This meta-analysis of preclinical animal studies suggested that RES may have potential in alleviating MIRI and MI. However, the translational potential of RES remains uncertain, and additional preclinical studies with standardized protocols, comorbid models, and eventual clinical trials are needed to confirm these results.

本荟萃分析旨在评估白藜芦醇(RES)对动物心肌缺血/再灌注损伤(MIRI)和心肌梗死(MI)的心脏保护作用。检索PubMed、Web of Science和EMBASE。主要结局包括心肌梗死面积(IS)和心功能。次要结局包括心脏损伤酶、氧化应激水平、炎症细胞因子和细胞凋亡率。采用亚组分析、发表偏倚、敏感性分析、meta回归和剂量-疗效分析评价偏倚风险。其中包括57项研究,涉及1125只动物。结果显示,RES治疗降低了MIRI动物模型的IS (SMD: -5.44; 95% CI [-6.42 ~ -4.45]; P 2 = 86%)和MI (SMD: -3.41; 95% CI [-4.44 ~ -2.38]; P 2 = 75%)。此外,在MIRI和MI动物模型中,RES治疗改善了心功能,降低了心脏损伤酶,下调了氧化应激水平,减轻了炎症细胞因子水平,降低了细胞凋亡率。这项临床前动物研究的荟荟性分析表明,RES可能具有减轻MIRI和MI的潜力。然而,RES的转化潜力仍然不确定,需要进一步的标准化方案、共病模型、最终的临床试验需要证实这些结果。
{"title":"Cardioprotective effect of resveratrol in myocardial ischemia/reperfusion injury and myocardial infarction: a pre-clinical meta-analysis in animal studies.","authors":"Shi-Jie Wei, Qi-Hao Guo, Xin-Yu Wei, Si-Yu Chen, Sheng Deng, Liang An, Wen-Jing Zeng, Yi-Fan Zeng","doi":"10.7717/peerj.20708","DOIUrl":"10.7717/peerj.20708","url":null,"abstract":"<p><p>This meta-analysis aimed to assess the cardioprotective effect of resveratrol (RES) against myocardial ischemia/reperfusion injury (MIRI) and myocardial infarction (MI) in the animal. PubMed, Web of Science, and EMBASE were searched. Primary outcomes included myocardial infarct size (IS) and cardiac function. Secondary outcomes included cardiac injury enzyme, oxidative stress level, inflammatory cytokine, and apoptosis rate. Subgroup analysis, publication bias, sensitivity analysis, meta-regression, and dosage-efficacy analysis were used to evaluate the risk of bias. Fifty-seven studies were included involving 1,125 animals. The results showed that RES treatment decreased IS in animal models of MIRI (SMD: -5.44; 95% CI [-6.42 to -4.45]; <i>P</i> < 0.01; I<sup>2</sup> = 86%) and MI (SMD: -3.41; 95% CI [-4.44 to -2.38]; <i>P</i> < 0.01; I<sup>2</sup> = 75%). Moreover, RES treatment improved cardiac function, decreased cardiac injury enzymes, down-regulated oxidative stress levels, alleviated inflammatory cytokine levels, and reduced apoptosis rate in animal models of MIRI and MI. This meta-analysis of preclinical animal studies suggested that RES may have potential in alleviating MIRI and MI. However, the translational potential of RES remains uncertain, and additional preclinical studies with standardized protocols, comorbid models, and eventual clinical trials are needed to confirm these results.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":"14 ","pages":"e20708"},"PeriodicalIF":2.4,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12882730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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