Pakistan Journal of Medical and Health Sciences最新文献

{"title":"Resilience: A Coping Strategy for Physical and Psychological Challenges faced by Chronic Kidney Disease patients","authors":"Abeeha Imran, Rubeena Zakar, Ruhma Shahzad, Babar Hussain, R. Ahmed","doi":"10.53350/pjmhs202317621","DOIUrl":"https://doi.org/10.53350/pjmhs202317621","url":null,"abstract":"Aim: To explore the lived experiences of patients suffering from chronic kidney disease (CKD)to understand how the physical and psychological challenges associated with the disease influenced their life and what role did resilience play to cope up with the physical and psychological challenges. Method: The present study is qualitative in nature and used the phenomenological research design to study the lived experiences of CKD patients. Thirty seven participants were selected through purposive sampling from the nephrology departments of three government hospitals of Lahore which included Jinnah Hospital, Sheikh Zayed Hospital and General Hospital. Data was collected through in-depth interviews. Results: The study revealed that resilience is a major factor which helps to cope up with the physical and psychological challenges associated with CKD by reducing stress, developing a positive self-image, encouraging to fight back, finding alternative treatment options and increasing the will power of CKD patients. Practical implications: Findings of the present study will be helpful for the health care professionals and clinical psychologists to develop strategies and training programs which can increase resilience among patients. Training the patients and care givers regarding how to fight with CKD will lead to an improvement in their quality of life. Conclusion: Resilience enables CKD patients to have a self-worth and brings them back to life by motivating them to participate in the normal activities of life. On the basis of these results, it is expected that this factor can be helpful for the health care professionals, caregivers and patients themselves in order to minimize the negative impacts of the disease through counseling. Keywords: Chronic kidney disease, Resilience, Physical challenges, Psychological challenges","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"272 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80646561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use and Outcome of Remdesivir in patients with COVID 19 presenting to Mayo Hospital Lahore","authors":"Hina Latif, N. Butt, Rabia Rathore, F. A. Randhawa, Adil M. Iqbal, Tayyab Latif","doi":"10.53350/pjmhs202317637","DOIUrl":"https://doi.org/10.53350/pjmhs202317637","url":null,"abstract":"Aim: To assess the usage of Remdesivir in COVID 19 patients admitted to Mayo hospital Lahore Methods: This Quasi experimental study was carried out in COVID-19 ward from July 2020 to September 2020 on patients presenting to Mayo Hospital with COVID-19.The sample size (n=150) was calculated through non-probability convenient sampling technique. We gave intravenous Remdesivir to hospitalized COVID-19 patients with proven SARS-CoV-2 infection with an oxygen saturation of ≤94% who were breathing ambient air or needed oxygen support and had an oxygen saturation of less than 94%. Remdesivir was administered to patients over the course of a 10-day course, starting with 200 mg intravenously (I/V) on day 1 and continuing with 100 mg per day for the following nine days. Results: Among 150 participants in our study, 103 (69%) were male and 47(31.3%) were females. Mean age was 57.37±13.42years. Selected parameters were evaluated at day 1, 5 and 10. Significant improvement in fever, dyspnea score, serum C- Reactive proteins (CRP) and lactate dehydrogenase (LDH) was found on day 1 and 10 with a p value of 0.01 to 0.000 for CRP and 0.48 to 0.000 for LDH respectively. Serum ferritin also showed a statistical difference with a significant p value of 0.038 at day 10 as compared to day 1 and 5. Conclusion: Among patients presenting with severe Covid-19, clinical improvement was noticed earlier in those who received Remdesivir than those who didn’t receive this drug. Measurement of effectiveness will require ongoing randomized controlled trials of Remdesivir drug therapy. Keywords: COVID-19, intravenous Remdesivir, earlier clinical improvement, outcome, oxygen support, breathlessness","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75810812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-sectional Investigation of Gastroenteritis Inflicted by Salmonella Typhi, Entamoebahistolytica and Giardia lamblia in Karachi, Pakistan","authors":"Muhammad Salman Rasool, Wajahat Hussain Shah, Agha Asad Noor, Kauser Siddiqui, A. H. Shar, N. A. Rind, Q. Ain, P. A. Shar, Sohail Ahmed Otho, Aliya Raza","doi":"10.53350/pjmhs202317625","DOIUrl":"https://doi.org/10.53350/pjmhs202317625","url":null,"abstract":"Background: Gastroenteritis is a global health concern affecting individuals of all ages and regions. The disease is caused bacteria, viruses, and parasites, and is characterized by symptoms such as diarrhea, abdominal pain, and nausea. Salmonella Typhi, Entamoeba histolytica, and Giardia lamblia are three prevalent pathogens worldwide responsible for causing gastroenteritis. Aim: To provide valuable insights into the prevalence, burden, and symptomatology of gastroenteritis caused by S. Typhi, E. histolytica, and G. lamblia in various areas of Karachi. Methods: To gather data, official registers of hospital wards, outpatient departments (OPDs), and relevant diagnostic laboratories were consulted. Stool microscopy, blood culture, Typhi Dot, and/or Widal tests were performed and their results recorded. The study collected data from a total of 1029 patients. Results: The frequency gastroenteritis rates (including cases of Typhoid, Amoebiasis, and Giardiasis), Typhoid fever, Amoebiasis, and Giardiasis were found as 71%, 57%, 30%, and 13% respectively. Conclusions: Based on the findings, the most common symptom in Typhoid cases was fever, followed by headache and abdominal pain. In Giardiasis and Amoebiasis cases, pain in abdomin was the most frequently reported symptom. By understanding the epidemiology of gastroenteritis caused by these agents, this research will add to the advancement of effective public health approaches to prevent and control gastroenteritis outbreaks in the future. Keywords: Gastroenteritis, Typhoid, Amoebiasis, Giradiasis, Salmonella Typhi, Entamoeba histolytica, Giardia lamblia","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90740910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontal Status of Tuberculosis patients - Inter linked with each other","authors":"Ziaulhaq Shahzad, F. Ahmad, S. Danish, S. Butt","doi":"10.53350/pjmhs2023176141","DOIUrl":"https://doi.org/10.53350/pjmhs2023176141","url":null,"abstract":"Background: Evidence suggests periodontitis may contribute to the development and progression of respiratory illnesses. However, few studies currently look at the coexistence of periodontitis and tuberculosis. The current study investigates the relationship between periodontal health and tuberculosis. Aim: To assess various clinical dental parameters of periodontal health among patients with and without TB. Methods: The participants in the present case-control study were individuals who obtained informed permission forms to participate when they were patients in the outpatient dentistry department. The current study included 585 patients in total. Three hundred-one individuals with normal pulmonary function were added to the control group, whereas 284 patients with tuberculosis were added to the cases group. The diagnosis of the pulmonary conditions was confirmed using spirometry. Using SPSS software 21, we evaluated the demographics & clinical indicators such as plaque, different gingival parameters of periodontitis, Gingival bleeding, and gingival index (GI), and compared cases and controls. Results: The population comprised two hundred eighty-seven women (49.1%) and 298 men (50.9%). There was a significant association between tuberculosis and periodontitis, and it has been observed that 159 (56%) tuberculosis patients had 6.23 (4.2 – 9.1) times higher effects on oral periodontitis issues (P<0.001*). Patients with gingivitis had a significantly higher number of bleeding, accounting for 241 (72.8), p<0.001. Practical implication: The study suggests that healthcare providers, particularly those involved in the treatment of TB, should consider incorporating oral health screening and assessment as part of the overall care for TB patients. This could help identify and address periodontal issues that may exist, hence dental professionals can play a role in the early detections of TB Conclusion: This study suggest that important relationship between TB and periodontitis. TB patients should be educated about the potential impact of their disease on periodontal health and encouraged to maintain regular dental visit and oral hygiene. Keywords: Tuberculosis (TB), Periodontitis (PD), Gingival bleeding, and gingival index (GI)","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90053044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic, Clinical, Laboratory and Radiological Spectrum of COVID-19 patients","authors":"Abdul Rabb Bhutto, A. Abbasi, K. Rehman","doi":"10.53350/pjmhs202317649","DOIUrl":"https://doi.org/10.53350/pjmhs202317649","url":null,"abstract":"Aim: To find out the demographic, clinical, laboratory and radiological spectrum of COVID-19 patients. Study design: Cross-sectional observational study. Place and duration of study: Al-Tibri Medical College Hospital, Isra University Karachi campus Karachi from June 2021 to December 2021. Methodology: The study enrolled adult patients of both genders with COVID-19 infection confirmed through positive qualitative RT‑PCR from nasal swab. After obtaining informed consent each confirmed patient with COVID-19 disease underwent a process of detailed medical history, clinical examination, laboratory tests, and radiological assessment. Based on presentation patients were divided into three groups; Group I, asymptomatic patients having only positive for COVID 19 were advised for self-isolation at home, Group 2 patients with mild symptoms and admitted to ward for observation and monitoring, while Group 3 were patients with moderate to severe disease and requiring intensive care. Results: A total of 179 patients with a mean age of 49.21813.237 years (rang 18 to 85 years) were enrolled in the study with gender based presentation 51 (28.5%) were women and 128 (71.5%) were men. Clinically; main symptoms were fever in 155 (86.6%), shortness of breath 129(72.1%), cough 126 (70.39%), and body ache in 104 (58.1%). Twenty six (14.5%) patients were asymptomatic (Group I), 107(59.8%) were symptomatic mild disease (Group II) and 37 (20.7%) patients presented with moderate to severe symptomatic illness (Group III). The majority of study participants 140 (78.21%) have various comorbidities, DM 60(33.5%), hypertension in 61(34.1%). Conclusion: Our study has highlighted the variability of most aspects of COVID-19 and this might be the main reason why the spectrum of the disease cannot be predicted. Radiologic, pulmonary with clinical patterns are relatively specific but extra pulmonary involvement especially hepatic may misguide and worse the prognosis. Keywords: COVID-19. Pandemic. Demographic. Clinical. Laboratory. Radiologic. Spectrum.","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86113915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and Characterization of Klebsiella Pneumoniae in Different Clinical Samples at Tertiary Care Hospital, Lahore","authors":"Usman Mustafa, A. Ashraf, H. Z. Wadood, Ghaffar Ali, Mohsin Ali, Sheema Yousaf","doi":"10.53350/pjmhs202317666","DOIUrl":"https://doi.org/10.53350/pjmhs202317666","url":null,"abstract":"Aim: To identify and characterization of klebsiella pneumoniae in different clinical samples in tertiary care hospital, Lahore Methodology: These 90 samples include 12 sputum samples, 21 tracheal swab, 30 pus and 27 urine samples from LGH, Lahore. Sample size: 90 subjects Duration: 6 months i.e. 01-07-2022 to 31-12-2022 Study place: LGH, Lahore Gram staining, microscopy, sputum, tracheal swab, pus, and urine cultures, biochemical tests, and antibiotic susceptibility testing was performed for all samples. Statistical analysis was performed by using SPSS Software. Results: Among the 90 clinical samples, 50 (55.6%) were positive for K. pneumoniaand10 cases (11.1%) with other bacteria. 30 (33.3%) cases showed no growth. Colistin, meropenem, amikacin, and imipenem (8.3%) were sensitive to sputum samples. Colistin 38.1%, ceftazidime 4.7%, meropenem 4.7%, amikacin 9.5%, sulfamethoxazole 4.7%, gentamycin 9.5%, and imipenem 28.5% were sensitive in tracheal swab samples. Conclusion: The highest sensitivity was observed incefoperazone, cefotaxime, and ceftriaxone (53.3%) isolates in pus samples. Keywords: Klebsiellapneumoniae, pneumonia, urinary tract infections, sensitivity patterns.","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88334291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Ultrasonographic Estimated Fetal Weight at Term with Actual Birth Weight in Punjab","authors":"Asadullah ., Z. Haider, Muhammad Athar Shams Rana, Syed Muhammad Yousaf Farooq, S. Qayyum, Muhammad Amir Bilal, Fatima Binte Mustafa, Ramsha Shahbaz, A. Nawaz, M. Z. Abidin, R. Zafar, Samia Shahid","doi":"10.53350/pjmhs2023176190","DOIUrl":"https://doi.org/10.53350/pjmhs2023176190","url":null,"abstract":"Background: The fetus is thought to have an inherent growth potential that under normal circumstances, yields a healthy newborn of appropriate size. Knowledge of weight of fetus in intrauterine life is important for the obstetrician to decide the management plan for delivery whether it would be vaginal or cesarean section. Aim: To compare estimated fetal weight on ultrasound at term with actual birth weight in Bahawalnagar Punjab. Methodology: A cross sectional analytical study was conducted at Tahir Medical Complex Haroon Abad district Bahawalnagar. Data of 200 participants were designated done suitable sample method. SPSS version 21.0 was used for data analysis. Results: out of total number of 200 pregnant women, mean±S. D of estimated fetal weight were 3245.8150±17.53151, Mean ±S. D of actual birth weight were 3260.7700±17.80643. Mean±S.D of Biparietal diameter were 9.2325±0.23428. The minimum and maximum values were 8.70 and 9.76 respectively. Two hundred pregnant females were included in this study. Conclusion: This study indicates that estimation of Birth weight clearly has a role in management of labor and delivery in a term pregnancy. Among term singleton cephalic pregnancies studied, fetal weight estimation using Hadlock’s formula is comparable to ultrasound estimates for predicting the actual birth weight within 10%. This study also revealed the mean estimated weight through ultrasound were similar to actual weight. Our results indicated the diagnostic accuracy of ultrasound in estimation of birth weight to be considerably significant therefore it is a reliable modality for estimating fetal weight using the Biparietal diameter, femur length and abdominal circumference as compared to actual birth weight. Keywords: Expected Fetal weight, actual fetal weight, Biparietal diameter, abdominal circumferences, femur length.","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87431727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Manipulation with Different Types of Gloves on Various Mechanical properties and Setting Time of Putty-Type Silicone Impression Materials","authors":"S. Ayesha, Nauman Ahmed Noor, Aneela Qaisar, Maria Asmat","doi":"10.53350/pjmhs202317645","DOIUrl":"https://doi.org/10.53350/pjmhs202317645","url":null,"abstract":"Aim: To evaluate the effects of handling with different type of gloves on the setting time, compressive and tensile strength of putty-type silicone impression materials. Methodology: The study was conducted at COMSATS Lahore and was approved by IRB FMH College of Medicine and Dentistry. In this in-vitro study three different type of gloves (Polythene, Latex and Vinyl) and two different brands each of addition silicone (Flexceed and Elite P&P) and condensation silicone (Zetaplus and Cavex) impression materials were used. These materials were divided into four different groups (A, B, C and D). Each group was subdivided into four sub-groups based on the gloves used for manipulation. Sixty samples(n=20) of two brands each of addition (Elite P&PA, Flexceed B) and condensation silicones (Zetaplus C and Cavex D) were prepared and analyzed to evaluate the setting time, compressive strength and tensile strength of addition and condensation impression materials. The samples were subdivided into groups A1, B1, C1, D1 (Control), A2, B2. C2, D2 (Polythene gloves), A3, B3, C3,D3 (Vinyl gloves) and A4, B4, C4, D4(Latex) respectively. Results: There was a significant effect(p<0.5) on the setting time of Elite P &P when mixed with latex gloves(A4) and Flexceed when mixed with polythene(B2) and latex gloves(B4) There was significant (p<0.5) effect on the setting time of Zetaplus when mixed with vinyl(C3) and latex gloves(C4). There was significant (p<0.5) effect on the setting time of Cavex when mixed with polythene(D2), vinyl(D3) and latex gloves(D4). There was a significant (p<0.5) effect on the tensile strength of both brand of addition and condensation silicone when mixed with polythene, vinyl and latex gloves as compared to control group. There was significant effect on the compressive strength of both brand of addition and condensation silicone except that polythene gloves don’t affect the compressive strength of one group of addition silicon B2(Flexceed) Practical implications: Dental silicone type of impression materials are widely used to fabricate different indirect restorations. Gloves are essential to control cross infection for the safety of the dentist and the patients and cannot be avoided for manipulation of these materials. Worldwide, dentists use different types of gloves to manipulate silicone impression materials. The composition and type of gloves affect the setting time and properties of addition and condensation silicones, and ultimately, it can affect and compromise the clinical outcome too. Conclusion: Latex and polythene gloves should be avoided for the manipulation of addition and condensation silicones putty impression materials due to considerable effect on the setting time. Vinyl gloves are a better choice as all others affected the mechanical properties. Keywords: Addition silicones, Condensation silicones, tensile strength, compressive strength, setting time","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82292127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Adverse Maternal Outcome in Early Onset Versus Delayed Onset Preeclampsia","authors":"Saba Jehangir, R. Salam, Nasreen Akhtar, Nimra Bashir, Sara Akram, Farzana Sabir, S. Saeed","doi":"10.53350/pjmhs2023176164","DOIUrl":"https://doi.org/10.53350/pjmhs2023176164","url":null,"abstract":"Aim: To determine the association of adverse maternal outcome with early onset preeclampsia than delayed onset preeclampsia. Study Design: Cohort study. Place and Duration of Study: Department of Obstetrics & Gynecology Unit-II, DHQ Hospital, Mirpur, AJK from 30th December 2020 to 29th June 2021. Methodology: A total of 60 (30 early onset pre-eclampsia and 30 delayed onset pre-eclampsia) females of age 18-40 years with parity <5, presenting at gestational age >24 weeks were included. Patients with chronic or gestational diabetes (BSR>186mg/dl), chronic hypertension (BP≥140/90mmHg), cardiac disease (on medical record), multiple gestation (on ultrasound), abnormal placenta (abruption, previa, accrete, increta, percreta on ultrasound) were excluded. Females were evaluated for eclampsia (BP>160/100mmHg along with convulsions), DIC, HELLP syndrome and avascular tubular necrosis by using blood samples and ultrasound findings. Results: The adverse maternal outcome i.e. eclampsia was recorded in 11 (36.67%) in exposed group (early onset pre-eclampsia) versus 04 (13.33%) in unexposed group (delayed onset pre-eclampsia) (p= 0.053; relative risk = 2.75), acute tubular necrosis was recorded in 05 (16.67%) in exposed group (early onset pre-eclampsia) while 00 (0.0%) in unexposed group (delayed onset pre-eclampsia) (p = 0.099; relative risk = 11.00), DIC was recorded in 03 (10.0%) versus 00 (0.0%) respectively (p= 0.192; relative risk = 7.00) and HELLP syndrome in 06 (20.0%) versus 00 (0.0%) respectively (p = 0.076; relative risk = 13.0). Practical Implication: We recommend that a proper protocol should be designed in these high risk patients for antenatal monitoring and proper management plans in order to reduce the morbidity and mortality of the mother and fetus. Conclusion: This study concluded that adverse maternal outcome is higher in early onset preeclampsia as compared to delayed onset preeclampsia. Keywords: Preeclampsia, Adverse Maternal Outcome, Eclampsia.","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82856518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Malignant and Non-malignant Acquired Tracheoesophageal Fistulae Management Strategies and Outcomes","authors":"Munir Ahmad Baloch, N. Din, Shahida Munir, Shazia Ismail, Nazir Ahmad","doi":"10.53350/pjmhs2023176155","DOIUrl":"https://doi.org/10.53350/pjmhs2023176155","url":null,"abstract":"Aim: To compare the malignant and non-malignant acquired tracheoesophageal fistulae management strategies. Study design: Prospective study Place and duration of study: Bolan Medical College Teaching Hospital, Quetta from 1st January 2022 to 31st December 2022. Methodology: Sixty patients suffering from tracheoesophageal fistulae were enrolled. The patients were then divided into two groups where depending upon convenient sampling the first group was named as malignant while second was non-malignant group. The underlying etiology of each patient was recorded and assessments of clinical conditions were made through imaging and endoscopic techniques. The preoperative, intraoperative and stenting management strategies were applied on the enrolled cases. Single, double stenting was based on case to case. Results: The mean age of the cases with benign tracheoesophageal fistula was 10.5±1.2 years while those having malignant tracheoesophageal fistula was 51.2±6.5 years. There were total 20 cases of tracheoesophageal fistula with nonmalignant diagnosis while 40 cases with malignant tracheoesophageal fistula. Within the primary outcomes of the cases the preoperative mortality was higher in non-malignant cases than malignant while morbidity was much higher in the malignant cases with 35% in that presenting fistula recurrence. Practical Implication: Malignancy appeared to be the main cause of TEF in patients and their survival chances are also less. Conclusion: Stenting is best managing strategy in patients with improved survival rate malignant as well as non-malignant cases. Keywords: Malignancy, Fistula, Esophagus, Ventilator, Stenting","PeriodicalId":19842,"journal":{"name":"Pakistan Journal of Medical and Health Sciences","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75302086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}