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The Effectiveness of Adding a Health Education Program to Fibromyalgia Treatment: A Systematic Review of Randomized Controlled Trials and Meta-Analysis. 在纤维肌痛治疗中加入健康教育计划的有效性:随机对照试验和荟萃分析的系统回顾。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-18 DOI: 10.1016/j.pmn.2025.08.010
Andrés Arana-Rodríguez, Francisca María García-Padilla, Almudena Garrido-Fernández, Miriam Sánchez-Alcón, Julia Sánchez-Galloso, Álvaro-José Rodríguez-Domínguez

Objectives: Evaluate the effectiveness of adding health education programs to a fibromyalgia intervention, focusing on pain intensity and the impact of fibromyalgia on quality of life.

Design: Systematic review and meta-analysis of randomized controlled trials.

Data sources: Databases: Web of Science, Medline, Scopus, Cumulative Index to Nursing and Allied Health Literature, Latin American and Caribbean Health Sciences Literature and PsycINFO.

Review/analysis methods: Literature from 2005-2025 was reviewed. Risk of bias was assessed by two researchers using the Cochrane Collaboration's tool. Quality of evidence was measured using the Grading of Recommendations, Assessment, Development, and Evaluation tool.

Results: The systematic review included 7 randomized controlled trials. 6 studies were included in the meta-analysis of the impact of fibromyalgia on quality of life, and five in the pain intensity meta-analysis. Meta-analysis results showed that health education significantly reduced pain intensity (MD=-13.10; 95% CI [-22.06, - 4.14], p=0.004) and improved the impact of fibromyalgia on quality of life (SMD=-0.39; 95% CI [-0.55, -0.23], p<.001). Subgroup analyses showed that adding education to usual care led to clinically relevant reduction in pain intensity (MD=-19.53; 95% CI [-31.68, -7.39], p=0.002) and statistically significant improvement in the impacf of fibromyalgia on quality of life (SMD=-0.46; 95% CI [-0.66, -0.26], p < .001).

Conclusions: Health education programs are effective in improving pain intensity and reducing the impact of fibromyalgia on quality of life. Further research is needed to support findings.

Nursing practice implications: By implementing health education for fibromyalgia patients, nurses can improve outcomes, enhancing the quality of care provided.

目的:评估在纤维肌痛干预中加入健康教育项目的有效性,重点关注疼痛强度和纤维肌痛对生活质量的影响。设计:随机对照试验的系统评价和荟萃分析。数据来源:数据库:Web of Science, Medline, Scopus,护理和相关健康文献累积索引,拉丁美洲和加勒比健康科学文献和PsycINFO。回顾/分析方法:回顾2005-2025年的文献。偏倚风险由两名研究人员使用Cochrane协作的工具进行评估。证据质量采用推荐分级、评估、发展和评价工具进行测量。结果:系统评价纳入7项随机对照试验。6项研究被纳入纤维肌痛对生活质量影响的荟萃分析,5项研究被纳入疼痛强度荟萃分析。meta分析结果显示,健康教育可显著降低疼痛强度(MD=-13.10; 95% CI [-22.06, - 4.14], p=0.004),改善纤维肌痛对生活质量的影响(SMD=-0.39; 95% CI[-0.55, -0.23])。结论:健康教育方案可有效改善疼痛强度,降低纤维肌痛对生活质量的影响。需要进一步的研究来支持这些发现。护理实践启示:通过对纤维肌痛患者实施健康教育,护士可以改善治疗结果,提高护理质量。
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引用次数: 0
Enhancing Postoperative Pain Management in Cardiopulmonary Bypass Heart Surgery Patients: A Study on Nursing Intervention Informed by Behavior Change Theory. 加强体外循环心脏手术患者术后疼痛管理:基于行为改变理论的护理干预研究。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-17 DOI: 10.1016/j.pmn.2025.08.009
Youwei Zhao, Wei Wei, Zhenyu Su, Yanbo Dong, Zhiyuan Wang, Shichao Guo

Background: A majority of adults undergoing heart surgery involving cardiopulmonary bypass (CPB) will experience acute pain.

Aims: To explore the effects of nursing interventions based on behavior change theory (BCT) on pain severity, pain interference, sleep quality, perceived control, quality of life, and self-care abilities.

Methods: A total of 53 patients undergoing CPB heart surgery in one hospital were enrolled. The patients were divided into Behavior Change Theory (BCT) group (n = 33) and Usual Care (UC) group (n = 20), among whom patients in the UC group received routine nursing intervention, while patients in the BCT group received nursing intervention based on BCT. Patients were evaluated for pain, sleep, perceived control, quality of life, self-care abilities, Hamilton Anxiety Scale (HAMA), and Hamilton Depression Scale (HAMD) questionnaires at baseline and after the intervention.

Results: Individuals in the BCT group demonstrated reduced pain levels, improved quality of life, enhanced self-care abilities, and lower scores of the HAMA and HAMD scales compared to those in the UC group (all p < .05). Implementation of BCT resulted in improvements in perceptual control (p < .001), reductions in pain interference (p = .02), and pain severity (p = .03). Group effects remained significant in terms of perceived control and pain interference (both p < .05), with trends observed in pain severity after adjusting baseline difference variables (p < .10). Sleep quality, assessed by PSQI, did not differ significantly between groups (p = .288).

Conclusion: Nursing interventions rooted in BCT holds the potential to augment patients' perception of control, elevate quality of life, enhance self-care abilities, and alleviate pain after CPB heart surgery.

背景:大多数成年人接受心脏手术包括体外循环(CPB)会经历急性疼痛。目的:探讨基于行为改变理论的护理干预对疼痛严重程度、疼痛干扰、睡眠质量、感知控制、生活质量和自我照顾能力的影响。方法:选取同一医院行CPB心脏手术患者53例。将患者分为行为改变理论(Behavior Change Theory, BCT)组(n = 33)和常规护理(Usual Care, UC)组(n = 20),其中UC组患者接受常规护理干预,BCT组患者接受基于BCT的护理干预。在基线和干预后评估患者的疼痛、睡眠、感知控制、生活质量、自我照顾能力、汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)问卷。结果:与UC组相比,BCT组的个体表现出疼痛程度减轻,生活质量改善,自我护理能力增强,HAMA和HAMD量表得分较低(均p < 0.05)。实施BCT可改善知觉控制(p < 0.001),减少疼痛干扰(p = 0.02)和疼痛严重程度(p = 0.03)。在感知控制和疼痛干扰方面,组效应仍然显著(均p < 0.05),调整基线差异变量后观察到疼痛严重程度的趋势(p < 0.10)。通过PSQI评估的睡眠质量在两组之间没有显著差异(p = 0.288)。结论:基于BCT的护理干预有可能增强CPB心脏手术后患者的控制感,提高生活质量,增强自我护理能力,减轻疼痛。
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引用次数: 0
Development of a Risk Assessment Index System of Non-Specific Neck-Shoulder Pain in Physicians and Nurses: A Delphi and Analytic Hierarchy Process Study in China. 医师和护士非特异性颈肩痛风险评估指标体系的建立:德尔菲和层次分析法研究。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-17 DOI: 10.1016/j.pmn.2025.08.008
Yunxia Li, Qi Li, Lihui Zhang, Yamin Li, Sue Yuan

Background: Physicians and nurses experience a high prevalence of non-specific neck-shoulder pain (NNSP) and are exposed to multiple risk factors. However, no targeted tools comprehensively assess these risk factors.

Objective: This study aimed to develop assessment indicators for evaluating risk factors contributing to NNSP among physicians and nurses.

Design: A systematic literature review and Delphi method, guided by a theoretical framework, were employed to develop the index system.

Methods: This study utilized a theoretical framework based on ergonomics and the biopsychosocial pain model to collect multi-source data for developing a risk assessment index system. Initially, candidate indicators were identified through literature reviews, theoretical analysis, expert interviews, and consultations. Three rounds of the e-Delphi technique were conducted to identify indices potentially affecting neck-shoulder pain. Finally, the analytic hierarchy process (AHP) method was employed to calculate the relative weight of each indicator.

Results: After two rounds of expert consultation, the risk assessment index system reached a consensus, comprising six first-level indicators: workload factors, individual factors, work facilities and equipment factors, workspace and environment factors, organization management factors, and psychological factors. These were further divided into 14 second-level indicators and 82 third-level indicators. Among these, workload factors had the highest weight (0.2484), while psychological factors had the lowest (0.1019).

Conclusion: The risk assessment index system achieved expert consensus, confirming its scientific validity and practical applicability. It provides a structured approach to identifying risk factors and high-risk individuals for neck-shoulder pain among physicians and nurses.

背景:医生和护士经历非特异性颈肩痛(NNSP)的高患病率,并暴露于多种危险因素。然而,没有针对性的工具全面评估这些风险因素。目的:本研究旨在建立评估医师和护士NNSP危险因素的评估指标。设计:采用系统文献法和德尔菲法,在理论框架的指导下,制定指标体系。方法:本研究采用基于人体工程学的理论框架和生物心理社会疼痛模型,收集多源数据,建立风险评估指标体系。最初,候选指标是通过文献综述、理论分析、专家访谈和咨询确定的。进行了三轮e-Delphi技术来确定可能影响颈肩疼痛的指标。最后,采用层次分析法计算各指标的相对权重。结果:经过两轮专家咨询,风险评估指标体系达成共识,包括6个一级指标:工作量因素、个人因素、工作设施设备因素、工作空间与环境因素、组织管理因素、心理因素。这些指标又分为14个二级指标和82个三级指标。其中,工作负荷因素权重最高(0.2484),心理因素权重最低(0.1019)。结论:风险评价指标体系取得了专家共识,证实了其科学有效性和实用性。它提供了一种结构化的方法来识别医生和护士中颈肩疼痛的风险因素和高危人群。
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引用次数: 0
Pain Experience and Expectations in Oncological Outpatient and Their Caregivers: Phenomenological Study. 肿瘤门诊病人及其护理人员的疼痛体验和预期:现象学研究。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-15 DOI: 10.1016/j.pmn.2025.08.011
Alícia Minaya-Freire, Gemma Pou-Pujol, Sílvia Carbonell-Palau, Laura Montero-Aliguer, Érica Izquierdo-Sánchez, Ester Fontseré-Candell, Amal Andich, Anna Ramon-Aribau

Purpose: To identify the pain experiences of cancer patients and the expectations of patients and caregivers in relation to pain management.

Design: Phenomenological qualitative study.

Methods: We used convenience sampling to recruit patients who had experienced pain level ≥4 according to the Numeric Rating Scale and their caregivers. The interview script was developed from the Nursing Outcomes Classification. We conducted a narrative analysis of the content.

Results: Eleven participants (eight patients and three caregivers) were included. The results were grouped into three main themes: 1) the experience of pain: the description and consequences of pain on participants' lives, and the meaning it has for patients and caregivers; 2) pain management: pharmacological and non-pharmacological pain management, the support of friends and family, and the lack of references and empowerment in pain management), and 3) expectations: communication with professionals, care by nurses, and pain relief and support.

Conclusions: The participants' oncological pain was intense, persistent and complex. Outpatient management of pain was difficult and was conditioned by the knowledge of patients and caregivers, but also by the professional's degree of experience. Nurses should be trained in the evaluation and management of oncological pain, so that they can educate patients and caregivers.

目的:了解癌症患者的疼痛经历以及患者和护理人员对疼痛管理的期望。设计:现象学定性研究。方法:采用方便抽样的方法,招募疼痛等级≥4级的患者及其护理人员。访谈脚本是根据护理结果分类编制的。我们对内容进行了叙述性分析。结果:共纳入11名参与者(8名患者和3名护理人员)。结果分为三个主题:1)疼痛体验:疼痛对参与者生活的描述和后果,以及疼痛对患者和护理人员的意义;2)疼痛管理:药物和非药物疼痛管理,朋友和家人的支持,以及在疼痛管理中缺乏参考和授权),以及3)期望:与专业人员的沟通,护士的护理,疼痛缓解和支持。结论:参与者的肿瘤疼痛是强烈的、持续的和复杂的。疼痛的门诊管理是困难的,受患者和护理人员的知识限制,但也受专业人员的经验程度的影响。护士应该接受评估和管理肿瘤疼痛的培训,以便他们能够教育患者和护理人员。
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引用次数: 0
A Mixed Educational Program for Fibromyalgia Managed by a Nurse: A Retrospective Evaluation. 一项由护士管理的纤维肌痛混合教育计划:回顾性评价。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-15 DOI: 10.1016/j.pmn.2025.07.016
Besson Bernadette, Malochet Véronique, Bouzon Virginie, Anthus Valérie, Tauleigne Eliane, Sedes Lauriane, Ombret Marie-Claire, André Gilbert, Gadéa Emilie

Objectives: Current guidelines for the treatment of fibromyalgia support a multicomponent approach combining pharmacological and nonpharmacological interventions. The potential effectiveness of a nonpharmacological multicomponent pilot program combining psychosocial education, water-based therapy, and relaxation was assessed.

Methods: Participants with fibromyalgia attended 3-to-4-hour weekly sessions for 8 weeks. The sessions were held in groups of eight to nine patients and included physical and educational components. The physical component included a 1-hour balneotherapy followed by a 1-hour relaxation. The educational component included eight 1-to-2-hour sessions with pain specialists, trained nurses, a sleep specialist, a nutritionist, a psychologist, and a psychometrician. The program staff recorded self-reported symptoms at the start (T0), the end (week 8 [W8]), and 6 months after the end (month 6 [M6]) of the program, using the Fibromyalgia Impact Questionnaire (FIQ) and the Hospital Anxiety and Depression Scale (HADS) questionnaire.

Results: Sixty-eight patients (66 females, mean age 49 years) participated in the program and gave informed consent for the analysis. Fifty-six had data available for all questionnaires at all time points (T0, W8, and M6). Patients with a T0 FIQ score of ≥59 had higher mean T0 anxiety and T0 depression scores compared with other patients (anxiety: 15.1 [SD 4.43] v 12.2 [SD 2.63], p = .0014; depression: 11.7 [SD 3.68] v 10.1 [SD 3.63], p = .049). Compared to T0 values, the anxiety and depression scores significantly decreased at W8 (anxiety T0: 13.7 [SD 3.95] v. W8 12.3 [SD 4.04], p = .0009; depression T0: 11.0 [SD 3.71] v W8: 9.4 [SD 3.81], p = .0019); and the FIQ score significantly decreased at W8 in the group of patients with a T0 FIQ score ≥59 (T0 FIQ 69 [SD 7.82] v W8 FIQ 59.9 [SD 9.6], p = .0004).

Conclusions: This pilot analysis suggests that this multicomponent intervention has the potential to alleviate anxiety and depression symptoms and improve the quality of life of patients with fibromyalgia. Further randomized trials should assess the short- and long-term effectiveness of this intervention.

目的:目前纤维肌痛的治疗指南支持药物和非药物干预相结合的多组分方法。评估了结合心理社会教育、水疗法和放松疗法的非药物多成分试点项目的潜在有效性。方法:纤维肌痛患者每周参加3- 4小时的会议,持续8周。会议以8至9名患者为一组,包括体育和教育部分。物理部分包括1小时的浴疗,然后是1小时的放松。教育部分包括与疼痛专家、训练有素的护士、睡眠专家、营养学家、心理学家和心理测量学家进行的8次1至2小时的会议。项目工作人员在项目开始(T0)、结束(第8周[W8])和结束后6个月(第6个月[M6])使用纤维肌痛影响问卷(FIQ)和医院焦虑与抑郁量表(HADS)记录自我报告的症状。结果:68例患者(66例女性,平均年龄49岁)参与了该计划,并知情同意进行分析。56份问卷在所有时间点(T0、W8和M6)都有可用的数据。T0 FIQ评分≥59的患者与其他患者相比,T0焦虑和T0抑郁的平均得分更高(焦虑:15.1 [SD 4.43] vs 12.2 [SD 2.63], p = 0.0014;抑郁:11.7 [SD 3.68] vs 10.1 [SD 3.63], p = 0.049)。与T0值相比,W8的焦虑和抑郁评分显著降低(焦虑T0: 13.7 [SD 3.95] vs W8 12.3 [SD 4.04], p = 0.0009;抑郁T0: 11.0 [SD 3.71] vs W8: 9.4 [SD 3.81], p = 0.0019);T0 FIQ评分≥59的患者在W8时FIQ评分显著降低(T0 FIQ 69 [SD 7.82] vs W8 FIQ 59.9 [SD 9.6], p = 0.0004)。结论:这项初步分析表明,这种多组分干预有可能减轻纤维肌痛患者的焦虑和抑郁症状,并改善患者的生活质量。进一步的随机试验应该评估这种干预的短期和长期有效性。
{"title":"A Mixed Educational Program for Fibromyalgia Managed by a Nurse: A Retrospective Evaluation.","authors":"Besson Bernadette, Malochet Véronique, Bouzon Virginie, Anthus Valérie, Tauleigne Eliane, Sedes Lauriane, Ombret Marie-Claire, André Gilbert, Gadéa Emilie","doi":"10.1016/j.pmn.2025.07.016","DOIUrl":"https://doi.org/10.1016/j.pmn.2025.07.016","url":null,"abstract":"<p><strong>Objectives: </strong>Current guidelines for the treatment of fibromyalgia support a multicomponent approach combining pharmacological and nonpharmacological interventions. The potential effectiveness of a nonpharmacological multicomponent pilot program combining psychosocial education, water-based therapy, and relaxation was assessed.</p><p><strong>Methods: </strong>Participants with fibromyalgia attended 3-to-4-hour weekly sessions for 8 weeks. The sessions were held in groups of eight to nine patients and included physical and educational components. The physical component included a 1-hour balneotherapy followed by a 1-hour relaxation. The educational component included eight 1-to-2-hour sessions with pain specialists, trained nurses, a sleep specialist, a nutritionist, a psychologist, and a psychometrician. The program staff recorded self-reported symptoms at the start (T0), the end (week 8 [W8]), and 6 months after the end (month 6 [M6]) of the program, using the Fibromyalgia Impact Questionnaire (FIQ) and the Hospital Anxiety and Depression Scale (HADS) questionnaire.</p><p><strong>Results: </strong>Sixty-eight patients (66 females, mean age 49 years) participated in the program and gave informed consent for the analysis. Fifty-six had data available for all questionnaires at all time points (T0, W8, and M6). Patients with a T0 FIQ score of ≥59 had higher mean T0 anxiety and T0 depression scores compared with other patients (anxiety: 15.1 [SD 4.43] v 12.2 [SD 2.63], p = .0014; depression: 11.7 [SD 3.68] v 10.1 [SD 3.63], p = .049). Compared to T0 values, the anxiety and depression scores significantly decreased at W8 (anxiety T0: 13.7 [SD 3.95] v. W8 12.3 [SD 4.04], p = .0009; depression T0: 11.0 [SD 3.71] v W8: 9.4 [SD 3.81], p = .0019); and the FIQ score significantly decreased at W8 in the group of patients with a T0 FIQ score ≥59 (T0 FIQ 69 [SD 7.82] v W8 FIQ 59.9 [SD 9.6], p = .0004).</p><p><strong>Conclusions: </strong>This pilot analysis suggests that this multicomponent intervention has the potential to alleviate anxiety and depression symptoms and improve the quality of life of patients with fibromyalgia. Further randomized trials should assess the short- and long-term effectiveness of this intervention.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Procedural Pain Experience and Management Needs in Patients With Chronic Wounds: A Qualitative Descriptive Study 慢性伤口患者的程序性疼痛经历和管理需求:一项定性描述性研究。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-13 DOI: 10.1016/j.pmn.2025.08.003
Lingling Xiong M.S. , Fan Li M.S. , Yuchuan Yue B.S. , Hongqiong Sun M.S. , Xinjun Liu B.S.

Background

Patients with chronic wounds often suffer moderate to severe pain during dressing change process. However, procedural pain is frequently ignored or undervalued as an inevitable complication. The study was designed to describe the pain experience and needs of patients with chronic wounds during dressing change, to provide evidence for developing pain management strategies.

Methods

This qualitative descriptive study enrolled 18 patients with chronic wounds who experienced procedural pain from July to August 2024. Data were collected using semi-structured interviews. The interviews were audio-recorded and converted verbatim, and the data were iteratively analyzed using thematic analysis.

Results

Four themes were identified, “Characteristics of pain,” “Adverse effects caused by pain,” “Pain coping strategies” and “Pain support needs.” Procedural pain in patients with chronic wounds was severe, dynamic, and imposed physical, psychological, and social burdens. Despite the availability of numerous coping strategies, their practical application was inadequate. Patients desire to professional management from healthcare providers and supports from families and peers.

Conclusion

This study may help to clarify the current status of procedural pain problems in patients with chronic wounds. We call on healthcare professionals to focus on the needs of patients from multiple perspectives, and to join forces with professionals, families, and peer multi-support systems to develop targeted coping strategies to effectively alleviate procedural pain and improve patients' quality of life.
背景:慢性伤口患者在换药过程中经常出现中度至重度疼痛。然而,作为一种不可避免的并发症,程序性疼痛经常被忽视或低估。本研究旨在描述慢性伤口患者在换药过程中的疼痛体验和需求,为制定疼痛管理策略提供依据。方法:采用定性描述性研究方法,于2024年7月至8月对18例发生程序性疼痛的慢性伤口患者进行研究。数据收集采用半结构化访谈。对访谈进行录音和逐字转换,并对数据进行迭代的主题分析。结果:确定了四个主题:“疼痛特征”、“疼痛引起的不良影响”、“疼痛应对策略”和“疼痛支持需求”。慢性伤口患者的程序性疼痛是严重的,动态的,并且施加了身体,心理和社会负担。尽管有许多应对策略,但它们的实际应用并不充分。患者渴望医疗保健提供者的专业管理和家庭和同伴的支持。结论:本研究有助于阐明慢性创伤患者的程序性疼痛问题的现状。我们呼吁医护人员从多个角度关注患者的需要,并与专业人员、家属和同伴多方支持系统合作,制定有针对性的应对策略,有效减轻手术痛苦,提高患者的生活质量。
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引用次数: 0
Information for Readers 读者资讯
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-12 DOI: 10.1016/S1524-9042(25)00264-4
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引用次数: 0
Sex Differences in Inflammatory Biomarker Levels in Patients With Acute Myofascial Pain Syndrome: Observational Study. 急性肌筋膜疼痛综合征患者炎症生物标志物水平的性别差异:观察性研究
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-11 DOI: 10.1016/j.pmn.2025.07.015
Liza Grosman-Rimon, William Parkinson, Hance Clarke, Joel Katz, Jordan Rimon, Moshe Bondi, Sigal Eilat-Adar, Dinesh Kumbhare

Introduction: One of the most common chronic musculoskeletal pain disorders is myofascial pain syndrome (MPS). A previous study showed that the levels of inflammatory mediators and growth factors were elevated in MPS. The objective of the current study was to examine sex differences in inflammatory mediators in patients with acute MPS and asymptomatic controls.

Methods: This cross-sectional study included a total of 57 patients (33 females; 24 males) clinically diagnosed with acute MPS who were consecutively recruited from the hospital emergency department, and 31 healthy subjects (12 females; 19 males) who were recruited via advertisements in the hospital and community. Serum inflammatory mediators and growth factors were measured in patients with MPS within 24 hours of symptoms and in healthy controls, using antibody-immobilized beads on a Luminex analyzer.

Results: The levels of inflammatory mediators and growth factors were significantly higher in patients with MPS compared with healthy controls. No significant sex differences were observed in the MPS group in the levels of tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1), interleukin-8 (IL-8), macrophage inflammatory protein-1α (MIP-1α), interleukin-1α (IL-1α), fibroblast growth factor-2 (FGF-2), or platelet-derived growth factor (PDGF). Similarly, in healthy controls, no sex differences were found in TNF-α, MCP-1, IL-8, MIP-1α, MIP-1β, IL-1α, granulocyte-macrophage colony-stimulating factor (GM-CSF), or PDGF levels. Median G-CSF levels were significantly higher in males with MPS 103.0 (48.0-211.5) compared with females 51.7 (31.0-77.8) with MPS (χ(3) = 16.02, p < .05), while no sex differences were found in healthy controls. In males compared with females with MPS, there was a trend of higher median levels of GM-CSF, MIP-1β, and vascular endothelial growth factor. In healthy males compared with female controls, the levels of FGF-2 (105.2 [56.1-137.6] vs. 59.5 [38.8-80.7], χ(3) = 20.14, p = .04) and GM-CSF (19.9 [9.1-47.6] vs. 8.3 [4.2-11.9], χ(3) = 16.02, p = .03) were significantly higher.

Conclusion: The levels of several of the inflammatory mediators assessed in this study were elevated to a similar extent in both healthy males and females and those with acute MPS.

最常见的慢性肌肉骨骼疼痛疾病之一是肌筋膜疼痛综合征(MPS)。先前的一项研究表明,炎症介质和生长因子的水平在MPS中升高。当前研究的目的是检查急性MPS患者和无症状对照组中炎症介质的性别差异。方法:本横断面研究共纳入从医院急诊科连续招募的临床诊断为急性MPS的患者57例(女性33例,男性24例),以及通过医院和社区广告招募的健康受试者31例(女性12例,男性19例)。在出现症状的24小时内,在Luminex分析仪上使用抗体固定珠测量MPS患者和健康对照者的血清炎症介质和生长因子。结果:MPS患者的炎症介质和生长因子水平明显高于健康对照组。MPS组在肿瘤坏死因子-α (TNF-α)、单核细胞趋化蛋白-1 (MCP-1)、白细胞介素-8 (IL-8)、巨噬细胞炎症蛋白-1α (MIP-1α)、白细胞介素-1α (IL-1α)、成纤维细胞生长因子-2 (FGF-2)、血小板源性生长因子(PDGF)水平上无显著性差异。同样,在健康对照中,TNF-α、MCP-1、IL-8、MIP-1α、MIP-1β、IL-1α、粒细胞-巨噬细胞集落刺激因子(GM-CSF)或PDGF水平无性别差异。MPS患者中位G-CSF水平为103.0(48.0 ~ 211.5)的男性显著高于MPS患者中位G-CSF水平为51.7(31.0 ~ 77.8)的女性(χ(3) = 16.02, p < 0.05),而健康对照组中无性别差异。与患有MPS的女性相比,男性的GM-CSF、MIP-1β和血管内皮生长因子的中位数水平有升高的趋势。健康男性的FGF-2水平(105.2[56.1-137.6]比59.5 [38.8-80.7],χ(3) = 20.14, p = 0.04)和GM-CSF水平(19.9[9.1-47.6]比8.3 [4.2-11.9],χ(3) = 16.02, p = 0.03)显著高于女性对照组。结论:本研究中评估的几种炎症介质水平在健康男性和女性以及急性MPS患者中均有相似程度的升高。
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引用次数: 0
Exploring Established Cut-Off Points for Pain Levels in the Numeric Rating Scale: Insights From a Literature Overview 在数字评定量表中探索疼痛水平的既定分界点:来自文献综述的见解。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-06 DOI: 10.1016/j.pmn.2025.08.005
Aurora Monticelli M.Sc. , Bastiaan Van Grootven Ph.D., M.Sc., R.N.

Purpose

Measuring pain in various settings, such as hospitals or long-term care facilities, is commonly done through the use of numerical pain assessment scales, e.g. the Numeric Rating Scale. While cut-off points are already used in daily practice for pain management and quality monitoring, a better understanding of these thresholds is needed. The aim of this study is to identify cut-off points for different pain intensities on the Numeric Rating Scale in the existing Literature.

Design

Literature study.

Methods

The literature search aimed to identify articles that establish independent cut-off points for pain levels on the Numeric Rating Scale. PubMed and Embase were searched using an identical search string. Additionally, the grey literature was reviewed on Google Scholar. Papers were screened for relevancy using Rayyan. The data was extracted using a data abstraction manual and synthesised to describe the findings.

Results

A total of 21 papers were included in the overview of pain cut-off points. The identified cut-off points for pain vary widely across studies, with definitions of pain encompassing between one and five levels. Values for mild pain ranged between scores 0 and 5, with the most cited range being 1-4. Moderate pain ranged from 3 to 8, with 4-8 as the most cited range. Severe pain ranged from 5 to 10, with the most popular category of 7-10. There was little consistency between studies even within similar populations, highlighting the lack of consensus. A debate persists regarding the use of a single cut-off point versus a range, with some studies advocating for overlapping ranges while others support nonoverlapping thresholds.

Conclusion

Establishing a cut-off value for pain is challenging, with no consensus in the literature on what constitutes optimal values. This variability may be attributed to differences in study populations, pain type and study methodologies. This emphasizes the need for alternative assessment tools or the inclusion of additional measures alongside the NRS. It is crucial to reassess the current pain assessment guidelines that continue to rely on these cut-off points in clinical practice, as well as to reconsider policies that use cut-offs for quality monitoring.
目的:在医院或长期护理设施等各种环境中测量疼痛,通常通过使用数字疼痛评估量表,例如数字评定量表来完成。虽然切断点已经在日常实践中用于疼痛管理和质量监测,但需要更好地理解这些阈值。本研究的目的是在现有文献中确定数字评定量表上不同疼痛强度的分界点。设计:文献研究。方法:文献检索旨在识别在数字评定量表上建立疼痛水平独立分界点的文章。PubMed和Embase使用相同的搜索字符串进行搜索。此外,在b谷歌Scholar上对灰色文献进行了综述。使用Rayyan对论文进行相关性筛选。使用数据抽象手册提取数据,并综合描述发现。结果:疼痛分界点综述共纳入21篇论文。在不同的研究中,确定的疼痛分界点差别很大,疼痛的定义包括一到五个级别。轻度疼痛的评分范围在0到5分之间,被引用最多的范围是1-4分。中度疼痛的范围从3到8,其中4-8是被引用最多的范围。剧烈疼痛分为5到10级,最受欢迎的是7到10级。即使在相似的人群中,研究之间也几乎没有一致性,这凸显了共识的缺乏。关于使用单一截止点与范围的争论仍然存在,一些研究主张重叠范围,而另一些研究支持不重叠阈值。结论:建立疼痛的临界值是具有挑战性的,在文献中没有关于什么是最佳值的共识。这种差异可能归因于研究人群、疼痛类型和研究方法的差异。这就强调需要替代的评估工具或在全国人口登记制度的基础上纳入其他措施。重新评估目前在临床实践中继续依赖这些分界点的疼痛评估指南,以及重新考虑使用分界点进行质量监测的政策,这是至关重要的。
{"title":"Exploring Established Cut-Off Points for Pain Levels in the Numeric Rating Scale: Insights From a Literature Overview","authors":"Aurora Monticelli M.Sc. ,&nbsp;Bastiaan Van Grootven Ph.D., M.Sc., R.N.","doi":"10.1016/j.pmn.2025.08.005","DOIUrl":"10.1016/j.pmn.2025.08.005","url":null,"abstract":"<div><h3>Purpose</h3><div>Measuring pain in various settings, such as hospitals or long-term care facilities, is commonly done through the use of numerical pain assessment scales, e.g. the Numeric Rating Scale. While cut-off points are already used in daily practice for pain management and quality monitoring, a better understanding of these thresholds is needed. The aim of this study is to identify cut-off points for different pain intensities on the Numeric Rating Scale in the existing Literature.</div></div><div><h3>Design</h3><div>Literature study.</div></div><div><h3>Methods</h3><div>The literature search aimed to identify articles that establish independent cut-off points for pain levels on the Numeric Rating Scale. PubMed and Embase were searched using an identical search string. Additionally, the grey literature was reviewed on Google Scholar. Papers were screened for relevancy using Rayyan. The data was extracted using a data abstraction manual and synthesised to describe the findings.</div></div><div><h3>Results</h3><div>A total of 21 papers were included in the overview of pain cut-off points. The identified cut-off points for pain vary widely across studies, with definitions of pain encompassing between one and five levels. Values for mild pain ranged between scores 0 and 5, with the most cited range being 1-4. Moderate pain ranged from 3 to 8, with 4-8 as the most cited range. Severe pain ranged from 5 to 10, with the most popular category of 7-10. There was little consistency between studies even within similar populations, highlighting the lack of consensus. A debate persists regarding the use of a single cut-off point versus a range, with some studies advocating for overlapping ranges while others support nonoverlapping thresholds.</div></div><div><h3>Conclusion</h3><div>Establishing a cut-off value for pain is challenging, with no consensus in the literature on what constitutes optimal values. This variability may be attributed to differences in study populations, pain type and study methodologies. This emphasizes the need for alternative assessment tools or the inclusion of additional measures alongside the NRS. It is crucial to reassess the current pain assessment guidelines that continue to rely on these cut-off points in clinical practice, as well as to reconsider policies that use cut-offs for quality monitoring.</div></div>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":"26 6","pages":"Pages 689-695"},"PeriodicalIF":2.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Progressive Muscle Relaxation on Pain and Sleep: Randomized Controlled Study. 渐进式肌肉放松对疼痛和睡眠的影响:随机对照研究。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-09-06 DOI: 10.1016/j.pmn.2025.08.006
Gamze Bolattürk, Emine Kol

Purpose: This study aimed to evaluate the effectiveness of Progressive Muscle Relaxation (PMR) on postoperative pain level and sleep quality in patients undergoing open heart surgery.

Design: A single center, two-group, single-blind randomized controlled trial.

Methods: This study comprised 60 patients who were admitted to the cardiovascular surgery department and undergoing open heart surgery between January 2023 and April 2024. Patients were randomized into 30 in the experimental group and 30 in the control group. Data were collected using Patient Identification Form, Short-form of McGill's Pain Questionnaire (SF-MPQ) and Richard-Campbell Sleep Questionnaire (RCSQ). PMR were applied twice a day, morning and evening, on the post-operative days 1st, 2nd, and 3rd days to experimental group. Before and after PMR, the patients' pain level and sleep quality were evaluated. The control group received usual care and treatment.

Results: In the experimental group, pain level decreased significantly from 9.36 points on the 1st day to 1.50 points on the 3rd day in the post-operative service (p0.001). In the control group, pain level decreased only to 6.13 points on the 3rd day. It was determined that sleep quality gradually increased in the experimental group and reached 545.83 points on the 3rd day in the post-operative service. In the control group, it increased only to 330.16 points. A significant difference was found pain level and sleep quality in all measurements between the experimental and control groups.

Conclusions: In this study, it was suggested that progressive muscle relaxation reduces pain and improves sleep quality in patients undergoing open heart surgery. It is recommended that nurses include progressive muscle relaxation in postoperative pain control and sleep management in usual care.

目的:本研究旨在评价渐进式肌肉放松(PMR)对心脏直视手术患者术后疼痛水平和睡眠质量的影响。设计:单中心、两组、单盲随机对照试验。方法:本研究纳入了2023年1月至2024年4月期间在心血管外科接受心内直视手术的60例患者。将患者随机分为实验组30例,对照组30例。采用患者识别表、McGill疼痛问卷简表(SF-MPQ)和Richard-Campbell睡眠问卷(RCSQ)收集数据。实验组于术后第1、2、3天每天早晚两次应用PMR。评估PMR前后患者的疼痛程度和睡眠质量。对照组接受常规护理和治疗。结果:实验组患者术后疼痛水平由第1天的9.36分降至第3天的1.50分,差异有统计学意义(p0.001)。在对照组中,疼痛水平在第3天仅下降到6.13分。确定实验组睡眠质量逐渐提高,术后第3天达到545.83分。在对照组中,它只增加到330.16分。在实验组和对照组之间的所有测量中,疼痛程度和睡眠质量都有显著差异。结论:在本研究中,提示渐进式肌肉放松可减轻心内直视手术患者的疼痛并改善睡眠质量。建议护士在术后疼痛控制和睡眠管理中加入渐进式肌肉放松。
{"title":"Effects of Progressive Muscle Relaxation on Pain and Sleep: Randomized Controlled Study.","authors":"Gamze Bolattürk, Emine Kol","doi":"10.1016/j.pmn.2025.08.006","DOIUrl":"https://doi.org/10.1016/j.pmn.2025.08.006","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness of Progressive Muscle Relaxation (PMR) on postoperative pain level and sleep quality in patients undergoing open heart surgery.</p><p><strong>Design: </strong>A single center, two-group, single-blind randomized controlled trial.</p><p><strong>Methods: </strong>This study comprised 60 patients who were admitted to the cardiovascular surgery department and undergoing open heart surgery between January 2023 and April 2024. Patients were randomized into 30 in the experimental group and 30 in the control group. Data were collected using Patient Identification Form, Short-form of McGill's Pain Questionnaire (SF-MPQ) and Richard-Campbell Sleep Questionnaire (RCSQ). PMR were applied twice a day, morning and evening, on the post-operative days 1st, 2nd, and 3rd days to experimental group. Before and after PMR, the patients' pain level and sleep quality were evaluated. The control group received usual care and treatment.</p><p><strong>Results: </strong>In the experimental group, pain level decreased significantly from 9.36 points on the 1st day to 1.50 points on the 3rd day in the post-operative service (p0.001). In the control group, pain level decreased only to 6.13 points on the 3rd day. It was determined that sleep quality gradually increased in the experimental group and reached 545.83 points on the 3rd day in the post-operative service. In the control group, it increased only to 330.16 points. A significant difference was found pain level and sleep quality in all measurements between the experimental and control groups.</p><p><strong>Conclusions: </strong>In this study, it was suggested that progressive muscle relaxation reduces pain and improves sleep quality in patients undergoing open heart surgery. It is recommended that nurses include progressive muscle relaxation in postoperative pain control and sleep management in usual care.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Pain Management Nursing
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