Lenka Jyotirmayee, Snehalata Khuntia, Nikita Panda, Kar Basudeba, Sahoo Suprava
Respiratory tract infections (RTIs) are common infections in the global population, particularly among children. Due to the rise of antibiotic resistance, multidrug-resistant bacteria, and the numerous adverse effects of synthetic drugs, there is a constant demand for new and safe alternative treatments. Natural plant-based alternatives have become more popular, while chemical drugs have been questioned for their safety and side effects. One of the most promising solutions to the global issue of respiratory tract infections is the exploration of the antiviral and antibacterial properties of essential oils (EOs). Because of their volatility, EOs can be inhaled, allowing them to reach both the upper and lower respiratory tracts. Additionally, their antimicrobial and anti-inflammatory properties along with their phytochemical composition make them more effective for treating respiratory tract infections. Humans are less likely to be affected by EOs because of their low toxicity and less risk of resistance to pathogenic organisms. Lamiaceae (also called Labiatae) is one of the most important herbal families, and it incorporates a wide range of plants like thyme, holy basil, rosemary, basil, etc. with potential therapeutic properties. The pharmacological properties of Lamiaceae are mainly due to its EOs, which have various activities like anti-tumor, anti-diabetic, insecticidal, neuroprotective, anti-asthmatic, and others. Overall, the main objective of this review is to provide an overview of the general characteristics of certain EOs from the Lamiaceae family about their ability to alleviate the signs and symptoms of respiratory diseases, including respiratory tract infections.
{"title":"The potential of Lamiaceae essential oils against respiratory tract diseases – a mini-review","authors":"Lenka Jyotirmayee, Snehalata Khuntia, Nikita Panda, Kar Basudeba, Sahoo Suprava","doi":"10.14719/pst.2554","DOIUrl":"https://doi.org/10.14719/pst.2554","url":null,"abstract":"Respiratory tract infections (RTIs) are common infections in the global population, particularly among children. Due to the rise of antibiotic resistance, multidrug-resistant bacteria, and the numerous adverse effects of synthetic drugs, there is a constant demand for new and safe alternative treatments. Natural plant-based alternatives have become more popular, while chemical drugs have been questioned for their safety and side effects. One of the most promising solutions to the global issue of respiratory tract infections is the exploration of the antiviral and antibacterial properties of essential oils (EOs). Because of their volatility, EOs can be inhaled, allowing them to reach both the upper and lower respiratory tracts. Additionally, their antimicrobial and anti-inflammatory properties along with their phytochemical composition make them more effective for treating respiratory tract infections. Humans are less likely to be affected by EOs because of their low toxicity and less risk of resistance to pathogenic organisms. Lamiaceae (also called Labiatae) is one of the most important herbal families, and it incorporates a wide range of plants like thyme, holy basil, rosemary, basil, etc. with potential therapeutic properties. The pharmacological properties of Lamiaceae are mainly due to its EOs, which have various activities like anti-tumor, anti-diabetic, insecticidal, neuroprotective, anti-asthmatic, and others. Overall, the main objective of this review is to provide an overview of the general characteristics of certain EOs from the Lamiaceae family about their ability to alleviate the signs and symptoms of respiratory diseases, including respiratory tract infections.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":" 1173","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138960165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lalngaihmanawmi, P. Lalthanpuii, Lalbiakngheti Tlau, Lucy Lalawmpuii, Lalnundanga, K. Lalchhandama
The Devil’s tree (Alstonia scholaris (L.) R.Br.), a member of the Apocynaceae family, is recognised in various traditional systems for its efficacy in treating several diseases. In the Mizo traditional medicines of India, the bark extract is utilised as a remedy for bacterial and parasitic infections, among other ailments. To validate the therapeutic claim of the Mizo people, a methanolic extract of the bark was prepared and its chemical composition was analysed. The extract was found to contain alkaloids, carbohydrates, flavonoids, glycosides, phytosterols, saponins, tannins, and reducing sugars. The antioxidant components of the extract were quantified, revealing a phenolic content of 13.563±0.09 mg/g quercetin equivalent, a flavonoid content of 31.64±2.50 mg/g gallic acid equivalent, and a total antioxidant of 10.48±0.84 mg/g ascorbic equivalent. These findings underscore the plant’s cellular protective capacity. Furthermore, the antioxidant activities were assessed using 2,2-diphenyl-1-1-picryldrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. The plant extract exhibited significant antioxidant properties, with a half-maximal inhibitory concentration (IC50) value of 11.01 against free radicals generated from the DPPH reaction. Notably, the extract demonstrated broad-spectrum antibacterial activity against Gram-negative bacteria, including Escherichia coli and Salmonella typhi, as well as Gram-positive species such as Bacillus cereus, Enterococcus faecalis and Staphylococcus aureus. This study establishes A. scholaris as a medicinal plant with promising antimicrobial and pharmacological properties, containing chemical components that can be harnessed for therapeutic purposes.
{"title":"Phytochemical analysis, and antioxidant and antibacterial activities of Alstonia scholaris from Mizoram, India","authors":"Lalngaihmanawmi, P. Lalthanpuii, Lalbiakngheti Tlau, Lucy Lalawmpuii, Lalnundanga, K. Lalchhandama","doi":"10.14719/pst.2826","DOIUrl":"https://doi.org/10.14719/pst.2826","url":null,"abstract":"The Devil’s tree (Alstonia scholaris (L.) R.Br.), a member of the Apocynaceae family, is recognised in various traditional systems for its efficacy in treating several diseases. In the Mizo traditional medicines of India, the bark extract is utilised as a remedy for bacterial and parasitic infections, among other ailments. To validate the therapeutic claim of the Mizo people, a methanolic extract of the bark was prepared and its chemical composition was analysed. The extract was found to contain alkaloids, carbohydrates, flavonoids, glycosides, phytosterols, saponins, tannins, and reducing sugars. The antioxidant components of the extract were quantified, revealing a phenolic content of 13.563±0.09 mg/g quercetin equivalent, a flavonoid content of 31.64±2.50 mg/g gallic acid equivalent, and a total antioxidant of 10.48±0.84 mg/g ascorbic equivalent. These findings underscore the plant’s cellular protective capacity. Furthermore, the antioxidant activities were assessed using 2,2-diphenyl-1-1-picryldrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. The plant extract exhibited significant antioxidant properties, with a half-maximal inhibitory concentration (IC50) value of 11.01 against free radicals generated from the DPPH reaction. Notably, the extract demonstrated broad-spectrum antibacterial activity against Gram-negative bacteria, including Escherichia coli and Salmonella typhi, as well as Gram-positive species such as Bacillus cereus, Enterococcus faecalis and Staphylococcus aureus. This study establishes A. scholaris as a medicinal plant with promising antimicrobial and pharmacological properties, containing chemical components that can be harnessed for therapeutic purposes.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"49 42","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138995877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hoang Thanh Duong, Do Thi Thuy Linh, Le Xuan Duy, Tran Thanh Ha, Nguyen Cao Cuong, Phung Van Trung, Nguyen Minh Khoi, Le Quang Thao, Do Huu Nghi, Nguyen Tuan Hiep
A special alkaloid compound known as capsaicin, which can only be found in the fruit of the Capsicum plant, was isolated and tested for its anti-inflammatory activity. The purpose of this work is to establish a simple and quick approach for capsaicin purification utilizing centrifugal partition chromatography (CPC) as well as an effective method - accelerated solvent extraction (ASE), for extracting capsaicin from Capsicum chinense. After purification, capsaicin was validated by HPLC-DAD at 281 nm to be > 90% purity. The in vivo anti-inflammatory activity of the isolated capsaicin was also investigated, and the IC50 value of the capsaicin was determined to be 57.61 µg/mL. The current work emphasizes how an ASE and CPC system may combine to extract high-purity capsaicin from Capsicum chinense, which have the anti-inflammatory activity, as we evaluated in the experiment.
{"title":"A modern purification by accelerated solvent extraction and centrifugal partition chromatography and biological evaluation of capsaicin from Capsicum chinense","authors":"Hoang Thanh Duong, Do Thi Thuy Linh, Le Xuan Duy, Tran Thanh Ha, Nguyen Cao Cuong, Phung Van Trung, Nguyen Minh Khoi, Le Quang Thao, Do Huu Nghi, Nguyen Tuan Hiep","doi":"10.14719/pst.2684","DOIUrl":"https://doi.org/10.14719/pst.2684","url":null,"abstract":"A special alkaloid compound known as capsaicin, which can only be found in the fruit of the Capsicum plant, was isolated and tested for its anti-inflammatory activity. The purpose of this work is to establish a simple and quick approach for capsaicin purification utilizing centrifugal partition chromatography (CPC) as well as an effective method - accelerated solvent extraction (ASE), for extracting capsaicin from Capsicum chinense. After purification, capsaicin was validated by HPLC-DAD at 281 nm to be > 90% purity. The in vivo anti-inflammatory activity of the isolated capsaicin was also investigated, and the IC50 value of the capsaicin was determined to be 57.61 µg/mL. The current work emphasizes how an ASE and CPC system may combine to extract high-purity capsaicin from Capsicum chinense, which have the anti-inflammatory activity, as we evaluated in the experiment.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"67 4","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tasnia Khatun, Sheikh Mahfuja Khatun, Mumtarin Haque Mim, Jannatul Naim, Sopnil Ahmed Jahin, Mohammad Rashed Hossain, M. El‐Esawi, Mohammad Anwar Hossain
The generation of high-yielding rice mutants and their assessment under salt stress offers a great possibility to isolate salt tolerant line(s) with desired trait of interest. Two separate experiments were conducted at the seedling and reproductive stages of rice to assess the level of salinity tolerance of few advanced high-yielding rice mutants. In the first experiment, rice seedlings were grown under hydroponic conditions and 14-day-old seedlings were subjected to salt stress (EC=10 dS/m; 7 days). Salt stress caused significant reduction in root and shoot length and biomass and leaf chlorophyll content; however, a little reduction was found in the mutant Line-1. In contrast, a sharp increase in shoot Na+/K+ ratio was found in all the genotypes except, Binadhan-10, FL-478 and the mutant Line-1, which exhibited little increased ratio. The second experiment involved exposure of plant to salt stress (EC=10 dS/m) for three weeks at the late booting stage in a sizable plastic tub filled with field soil. Salt stress resulted in a significant decrease in yield and yield attributing traits in all the genotypes except Binadhan-10. Grain yield per panicle was found significantly positive correlation with panicle length, the number of filled grains per panicle, and 100-seed weight under both control and salt stress conditions. Based on the studied traits and stress tolerance indices, Binadhan-10 and mutant Line-1 categorized as salt tolerant and rest of the genotypes were categorized as susceptible, which is also evident from the biplot of principal component analysis. Considering the results from both of the experiments, mutant Line-1 was found tolerant genotype at both seedling and reproductive stage. However, further studies are required to determine the genetic issues controlling the salinity tolerance in mutant Line-1 and the high-yield potential of mutant Line-65 under control condition in a way to develop salt tolerant and high-yielding rice varieties, respectively.
{"title":"Advanced Mutant Line Developed from Fatemadhan Shows Salinity Tolerance at both Seedling and Reproductive Stages","authors":"Tasnia Khatun, Sheikh Mahfuja Khatun, Mumtarin Haque Mim, Jannatul Naim, Sopnil Ahmed Jahin, Mohammad Rashed Hossain, M. El‐Esawi, Mohammad Anwar Hossain","doi":"10.14719/pst.2917","DOIUrl":"https://doi.org/10.14719/pst.2917","url":null,"abstract":"The generation of high-yielding rice mutants and their assessment under salt stress offers a great possibility to isolate salt tolerant line(s) with desired trait of interest. Two separate experiments were conducted at the seedling and reproductive stages of rice to assess the level of salinity tolerance of few advanced high-yielding rice mutants. In the first experiment, rice seedlings were grown under hydroponic conditions and 14-day-old seedlings were subjected to salt stress (EC=10 dS/m; 7 days). Salt stress caused significant reduction in root and shoot length and biomass and leaf chlorophyll content; however, a little reduction was found in the mutant Line-1. In contrast, a sharp increase in shoot Na+/K+ ratio was found in all the genotypes except, Binadhan-10, FL-478 and the mutant Line-1, which exhibited little increased ratio. The second experiment involved exposure of plant to salt stress (EC=10 dS/m) for three weeks at the late booting stage in a sizable plastic tub filled with field soil. Salt stress resulted in a significant decrease in yield and yield attributing traits in all the genotypes except Binadhan-10. Grain yield per panicle was found significantly positive correlation with panicle length, the number of filled grains per panicle, and 100-seed weight under both control and salt stress conditions. Based on the studied traits and stress tolerance indices, Binadhan-10 and mutant Line-1 categorized as salt tolerant and rest of the genotypes were categorized as susceptible, which is also evident from the biplot of principal component analysis. Considering the results from both of the experiments, mutant Line-1 was found tolerant genotype at both seedling and reproductive stage. However, further studies are required to determine the genetic issues controlling the salinity tolerance in mutant Line-1 and the high-yield potential of mutant Line-65 under control condition in a way to develop salt tolerant and high-yielding rice varieties, respectively.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"5 6","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138971941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Van Chen Tran, Minh-Nhut Truong, Thi Thuy Quynh Tran, Thanh To Nhi Nguyen, Hoang Khanh Linh Nguyen
Curcuma sahuynhensis Škornick. & N.S.Lý is an endemic plant in Vietnam that has been used by the Sa Huynh people as a spice and medicine to cure illnesses linked to digestive disorders. Very little information is available so far about the chemical composition and biological effects of C. sahuynhensis. To find new pharmaceutical ingredients, the in vitro cytotoxic effect and the chemical profile of C. sahuynhensis leaf extract were investigated. In this study, the percolation method and liquid-liquid dispersion technique were used to extract dry sample powder. The chemical composition was detected by gas chromatography-mass spectrometry (GC-MS). The Sulforhodamine B and MTT methods were used to determine the cytotoxic activity. The chemical composition analysis showed that the leaf extract contained 14 components. The major components in the n-hexane extract were 6,10,14-trimethylpentadecan-2-one, phytol, 1-ethylbutyl hydroperoxide, isoborneol, 1-methylpentyl hydroperoxide, and neophytadiene. On human cancer cell lines, namely MFC-7, SK-LU-1, Hela, MKN-7, and HL-60, the leaf extract showed dose-dependent cytotoxic activity, with IC50 values ranging from 221.70±10.24 to 369.42±10.60 ?g/mL. The present study provides significant information on the chemical components and cytotoxic effects of the n-hexane extract from C. sahuynhensis leaves. The findings will continue to be crucial in future research on the evaluation of secondary metabolite compound analysis for cancer therapeutic effects.
{"title":"GC-MS analysis and cytotoxic activity of the n-hexane fraction from Curcuma sahuynhensis Škornick. & N.S.Lý leaves collected in Vietnam","authors":"Van Chen Tran, Minh-Nhut Truong, Thi Thuy Quynh Tran, Thanh To Nhi Nguyen, Hoang Khanh Linh Nguyen","doi":"10.14719/pst.2881","DOIUrl":"https://doi.org/10.14719/pst.2881","url":null,"abstract":"Curcuma sahuynhensis Škornick. & N.S.Lý is an endemic plant in Vietnam that has been used by the Sa Huynh people as a spice and medicine to cure illnesses linked to digestive disorders. Very little information is available so far about the chemical composition and biological effects of C. sahuynhensis. To find new pharmaceutical ingredients, the in vitro cytotoxic effect and the chemical profile of C. sahuynhensis leaf extract were investigated. In this study, the percolation method and liquid-liquid dispersion technique were used to extract dry sample powder. The chemical composition was detected by gas chromatography-mass spectrometry (GC-MS). The Sulforhodamine B and MTT methods were used to determine the cytotoxic activity. The chemical composition analysis showed that the leaf extract contained 14 components. The major components in the n-hexane extract were 6,10,14-trimethylpentadecan-2-one, phytol, 1-ethylbutyl hydroperoxide, isoborneol, 1-methylpentyl hydroperoxide, and neophytadiene. On human cancer cell lines, namely MFC-7, SK-LU-1, Hela, MKN-7, and HL-60, the leaf extract showed dose-dependent cytotoxic activity, with IC50 values ranging from 221.70±10.24 to 369.42±10.60 ?g/mL. The present study provides significant information on the chemical components and cytotoxic effects of the n-hexane extract from C. sahuynhensis leaves. The findings will continue to be crucial in future research on the evaluation of secondary metabolite compound analysis for cancer therapeutic effects.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"105 5","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138971221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erwin Dafis Nasution, A. R. Saidy, B. J. Priatmadi, Hafizianor, Suwardi, Sukarman, Moch. Dasrial, Himmatul Ulya Alfiana, Rahman Jailani
The expansion of oil palm plantations is often rumored to impact the destruction of forests and other ecosystems with high conservation value (HCV). This study aimed to analyze the vegetation and plant diversity in the HCV area of oil palm plantations. The research was conducted on an oil palm plantation in Seruyan District, Central Kalimantan Province, Indonesia with an HCV area of 5379 ha. The research was carried out using the grid transect method on various types of vegetation, divided into four plots: seedlings, saplings, poles and trees. Parameters observed included the number of species, the number of individuals and the level of plant diversity. The results showed that the research location had good vegetation and plant diversity in the HCV area. There were 25 plant species from 17 families with a total of 355 plants. The number of species found in the seedling plots was 11 species (6 families) with a total of 38 plants; in the sapling plots was 16 species (12 families) with a total of 159 plants; in the pole plots was 14 species (11 families) with a total of 43 plants, and in the tree plots was 13 species (10 families) 115 plants. There was variation in the number of species and families in each plot. The overall plant diversity index was low. The diversity index of plants in the plots of seedlings, saplings, poles and trees (and the average) was in the low category.
{"title":"Analysis of Vegetation and Plant Diversity in High Conservation Value Areas in Oil Palm Plantations","authors":"Erwin Dafis Nasution, A. R. Saidy, B. J. Priatmadi, Hafizianor, Suwardi, Sukarman, Moch. Dasrial, Himmatul Ulya Alfiana, Rahman Jailani","doi":"10.14719/pst.2924","DOIUrl":"https://doi.org/10.14719/pst.2924","url":null,"abstract":"The expansion of oil palm plantations is often rumored to impact the destruction of forests and other ecosystems with high conservation value (HCV). This study aimed to analyze the vegetation and plant diversity in the HCV area of oil palm plantations. The research was conducted on an oil palm plantation in Seruyan District, Central Kalimantan Province, Indonesia with an HCV area of 5379 ha. The research was carried out using the grid transect method on various types of vegetation, divided into four plots: seedlings, saplings, poles and trees. Parameters observed included the number of species, the number of individuals and the level of plant diversity. The results showed that the research location had good vegetation and plant diversity in the HCV area. There were 25 plant species from 17 families with a total of 355 plants. The number of species found in the seedling plots was 11 species (6 families) with a total of 38 plants; in the sapling plots was 16 species (12 families) with a total of 159 plants; in the pole plots was 14 species (11 families) with a total of 43 plants, and in the tree plots was 13 species (10 families) 115 plants. There was variation in the number of species and families in each plot. The overall plant diversity index was low. The diversity index of plants in the plots of seedlings, saplings, poles and trees (and the average) was in the low category.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"27 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139233015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ghosh Ahana, P. Manikantan, Chaudhary Aditi, M. Arun, A. Vijaya Anand, B. Balamuralikrishnan, Meganathan Gomathy
Nanomaterial innovation is the primary catalyst of advancement in nanotechnology. Although there are many known chemical processes for creating nanoparticles that use harmful substances, it is now more important than ever to use processes that are safer, greener, and more environmentally friendly. The goal of research in this field is to use diverse life forms as "nanoparticle factories." Phytochemicals can convert salt into the appropriate nanoparticles thanks to their regular biosynthetic routes. In recent years, green chemistry methods for the synthesis of metallic nanoparticles have emerged as a fresh and exciting area of study. Metal nanoparticles, including gold (Au), silver (Ag), iron (Fe), and cadmium (Cd) along with certain oxides, can be synthesized using a variety of chemical and physical techniques as well as biological techniques carried out using plants. It has been discovered that methods involving plant-mediated synthesis are a more efficient and cost-effective way to create these metal nanoparticles. The plant-mediated nanoparticles are used as potential pharmaceutical agents for many diseases, including hepatitis, cancer, malaria, and HIV. Due to the higher efficacy and fewer side effects of nanodrugs compared to other commercial cancer drugs, the synthesis of nanoparticles targeting biological pathways has gained tremendous popularity. This review paper aims to cover the different green methods for the biogenesis of these nanoparticles, the different compounds and salts used, and the metals obtained. Ultimately, the significance and prospects of these metal nanoparticles especially in the fields of medicine, pharmacology, drug designing, and drug delivery engineering will also be commented on.
{"title":"Biogenesis and Green Synthesis of Metal Nanoparticles and Their Pharmacological Applications","authors":"Ghosh Ahana, P. Manikantan, Chaudhary Aditi, M. Arun, A. Vijaya Anand, B. Balamuralikrishnan, Meganathan Gomathy","doi":"10.14719/pst.2417","DOIUrl":"https://doi.org/10.14719/pst.2417","url":null,"abstract":"Nanomaterial innovation is the primary catalyst of advancement in nanotechnology. Although there are many known chemical processes for creating nanoparticles that use harmful substances, it is now more important than ever to use processes that are safer, greener, and more environmentally friendly. The goal of research in this field is to use diverse life forms as \"nanoparticle factories.\" Phytochemicals can convert salt into the appropriate nanoparticles thanks to their regular biosynthetic routes. In recent years, green chemistry methods for the synthesis of metallic nanoparticles have emerged as a fresh and exciting area of study. Metal nanoparticles, including gold (Au), silver (Ag), iron (Fe), and cadmium (Cd) along with certain oxides, can be synthesized using a variety of chemical and physical techniques as well as biological techniques carried out using plants. It has been discovered that methods involving plant-mediated synthesis are a more efficient and cost-effective way to create these metal nanoparticles. The plant-mediated nanoparticles are used as potential pharmaceutical agents for many diseases, including hepatitis, cancer, malaria, and HIV. Due to the higher efficacy and fewer side effects of nanodrugs compared to other commercial cancer drugs, the synthesis of nanoparticles targeting biological pathways has gained tremendous popularity. This review paper aims to cover the different green methods for the biogenesis of these nanoparticles, the different compounds and salts used, and the metals obtained. Ultimately, the significance and prospects of these metal nanoparticles especially in the fields of medicine, pharmacology, drug designing, and drug delivery engineering will also be commented on.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"148 ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139242598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Salvia genus, a member of the Lamiaceae family, exhibits a rich array of secondary metabolites, including di- and triterpenoids, phenols, polyphenols, and essential oil compounds. These constituents contribute to valuable pharmacological activities such as antibacterial, antiviral, anti-inflammatory, and antioxidant properties. Among these metabolites, rosmarinic acid stands out as a particularly promising compound, deriving from the precursors phenylalanine and tyrosine. It belongs to the phenolic compound class and acts as an ester of caffeic acid, showcasing diverse therapeutic potentials like antifungal, antibacterial, antiviral, antioxidant, anticancer, anti-ageing, anti-inflammatory, and anti-diabetic effects. To facilitate the production of such secondary metabolites, plant tissue culture techniques have played a pivotal role, with hairy root cultures being one of the preferred methods. This review provides an extensive examination of the biosynthetic pathway of rosmarinic acid and its successful generation using hairy root cultures. Additionally, the review highlights the utilization of genetic modification tools and various biotic and abiotic elicitors, including yeast extract, methyl jasmonate, and silver ion (Ag+), in hairy root cultures of diverse Salvia species to enhance the production of rosmarinic acid.
{"title":"Hairy roots as a potential source for the production of rosmarinic acid from genus Salvia","authors":"Somani Shriti, Agarwala Kuldeep Prasad, Wudali Narasimha Sudheer, Nagella Praveen","doi":"10.14719/pst.2541","DOIUrl":"https://doi.org/10.14719/pst.2541","url":null,"abstract":"The Salvia genus, a member of the Lamiaceae family, exhibits a rich array of secondary metabolites, including di- and triterpenoids, phenols, polyphenols, and essential oil compounds. These constituents contribute to valuable pharmacological activities such as antibacterial, antiviral, anti-inflammatory, and antioxidant properties. Among these metabolites, rosmarinic acid stands out as a particularly promising compound, deriving from the precursors phenylalanine and tyrosine. It belongs to the phenolic compound class and acts as an ester of caffeic acid, showcasing diverse therapeutic potentials like antifungal, antibacterial, antiviral, antioxidant, anticancer, anti-ageing, anti-inflammatory, and anti-diabetic effects. To facilitate the production of such secondary metabolites, plant tissue culture techniques have played a pivotal role, with hairy root cultures being one of the preferred methods. This review provides an extensive examination of the biosynthetic pathway of rosmarinic acid and its successful generation using hairy root cultures. Additionally, the review highlights the utilization of genetic modification tools and various biotic and abiotic elicitors, including yeast extract, methyl jasmonate, and silver ion (Ag+), in hairy root cultures of diverse Salvia species to enhance the production of rosmarinic acid.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"16 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139246126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana Jhulia Palheta de Sousa, Tamirys Marcelina da Silva, Marcio Augusto Costa Carmona Junior, Glauco André Dos Santos Nogueira, Ana Ecídia De Araújo Brito, Luma Castro de Souza, Cândido Ferreira de Oliveira Neto, Gerson Diego Pamplona Albuquerque
The aim of this work was applying salicylic acid (SA) in cowpea seedlings under saline stress. The experiment took place in the seed laboratory of the Universidade Federal Rural da Amazônia with a completely randomized experimental design in a 2 x 2 x 3 factorial scheme, with two bean cultivars (Canapu and Pingo-de-ouro), two levels of salicylic acid (0, and 0.50 mM) and three salt stress levels (0, 25, 50 mM). The seeds were previously soaked in salicylic acid (0 and 0.50 mM) for a period of 12 hours and then placed in germitest paper rolls for treatments with NaCl (0, 25, 50 mM) for a period of 12 days at room temperature constant 27 °C. There was a significant effect of cultivars, AS dose and NaCl concentrations and their interactions on most of the analyzed variables. Root and leaf proline concentrations were higher in pingo-de-ouro cultivar, Canapu cultivar had better performance in biomass accumulation. Salicylic acid reduced proteins in the leaves by 13.33%, while in the root there was an increase of 12.61%, ammonium concentrations reduced in the roots by 11.9%. When applied to salinity (25 and 50 mM) there was an increase of proteins in the leaves 40.83% and 27.48% respectively, and a reduction of amino acids of 30.24 and 25.24% in NaCl dosages (25 and 50 mM) respectively. Salinity reduced biomass accumulation and interfered with cellular solute production. However, the application of salicylic acid promoted salt stress tolerance in Canapu cultivar.
{"title":"Effect of salicylic acid on cowpea seedlings under saline stress","authors":"Diana Jhulia Palheta de Sousa, Tamirys Marcelina da Silva, Marcio Augusto Costa Carmona Junior, Glauco André Dos Santos Nogueira, Ana Ecídia De Araújo Brito, Luma Castro de Souza, Cândido Ferreira de Oliveira Neto, Gerson Diego Pamplona Albuquerque","doi":"10.14719/pst.2237","DOIUrl":"https://doi.org/10.14719/pst.2237","url":null,"abstract":"The aim of this work was applying salicylic acid (SA) in cowpea seedlings under saline stress. The experiment took place in the seed laboratory of the Universidade Federal Rural da Amazônia with a completely randomized experimental design in a 2 x 2 x 3 factorial scheme, with two bean cultivars (Canapu and Pingo-de-ouro), two levels of salicylic acid (0, and 0.50 mM) and three salt stress levels (0, 25, 50 mM). The seeds were previously soaked in salicylic acid (0 and 0.50 mM) for a period of 12 hours and then placed in germitest paper rolls for treatments with NaCl (0, 25, 50 mM) for a period of 12 days at room temperature constant 27 °C. There was a significant effect of cultivars, AS dose and NaCl concentrations and their interactions on most of the analyzed variables. Root and leaf proline concentrations were higher in pingo-de-ouro cultivar, Canapu cultivar had better performance in biomass accumulation. Salicylic acid reduced proteins in the leaves by 13.33%, while in the root there was an increase of 12.61%, ammonium concentrations reduced in the roots by 11.9%. When applied to salinity (25 and 50 mM) there was an increase of proteins in the leaves 40.83% and 27.48% respectively, and a reduction of amino acids of 30.24 and 25.24% in NaCl dosages (25 and 50 mM) respectively. Salinity reduced biomass accumulation and interfered with cellular solute production. However, the application of salicylic acid promoted salt stress tolerance in Canapu cultivar.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"13 2","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139243470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The structure of alpine plant populations is one of the main criteria for assessing the current state of alpine flora. Species of the genus Nepeta, most of which belong to alpine plants, can be universal objects for assessing changes in environmental conditions, including the impact of anthropogenic pressure. The article discusses the ontogenetic structure and population size in connection with the change in the life form of Nepeta pamirensis at different heights of the Pamirs (3060-4250 m a.s.l.). Our research showed that the ontogenetic spectra of different populations are different. These differences are linked to changes in the life form, the length of ontogenesis and how well seeds reproduce. Populations were studied using transects. The individual seed was taken as the counting unit. In total, 3 populations were studied and more than 750 individuals of different ontogenetic states were included in the analysis. The ontogenetic structure of populations was characterized using basic demographic indicators: the recovery index, ageing index, generative index and the ecological density index. Depending on the altitude gradient, the species was characterized by different efficiencies of seed reproduction, which determined the different densities of individuals in plant communities of distribution. In general, with an increase in the height of distribution of a species, the structure of the population became more stable.
{"title":"The population structure of Nepeta pamirensis at different altitudes in the Pamirs (Tajikistan)","authors":"Alexey Yurievich Astashenkov, V.A. Cheryomushkina, Maryio Tilloevich Boboev","doi":"10.14719/pst.2630","DOIUrl":"https://doi.org/10.14719/pst.2630","url":null,"abstract":"The structure of alpine plant populations is one of the main criteria for assessing the current state of alpine flora. Species of the genus Nepeta, most of which belong to alpine plants, can be universal objects for assessing changes in environmental conditions, including the impact of anthropogenic pressure. The article discusses the ontogenetic structure and population size in connection with the change in the life form of Nepeta pamirensis at different heights of the Pamirs (3060-4250 m a.s.l.). Our research showed that the ontogenetic spectra of different populations are different. These differences are linked to changes in the life form, the length of ontogenesis and how well seeds reproduce. Populations were studied using transects. The individual seed was taken as the counting unit. In total, 3 populations were studied and more than 750 individuals of different ontogenetic states were included in the analysis. The ontogenetic structure of populations was characterized using basic demographic indicators: the recovery index, ageing index, generative index and the ecological density index. Depending on the altitude gradient, the species was characterized by different efficiencies of seed reproduction, which determined the different densities of individuals in plant communities of distribution. In general, with an increase in the height of distribution of a species, the structure of the population became more stable.","PeriodicalId":20236,"journal":{"name":"Plant Science Today","volume":"26 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139242859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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