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Impacts of combined or single supplementation of branched-chain amino acids on delayed onset muscle soreness and muscle damage following resistance exercise 支链氨基酸联合或单独补充对阻力运动后迟发性肌肉酸痛和肌肉损伤的影响
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-03-05 DOI: 10.23751/PN.V20I2.5825
F. Asjodi, Reza Daryabeygi Khotbesara, B. P. Gargari, Azimeh Izadi
The purpose of this investigation was to determine and compare the effects of leucine (Leu), valine (Val), isoleucine (Ilue), and combined branched chain amino acids (BCAA) supplementation, on markers of muscle damage following resistance exercise. It was hypothesized that supplementation would attenuate the levels of indirect muscle damage markers and muscle soreness following exercise-induced muscle damage, and facilitate the restoration of muscle function. A total of 50 untrained males were randomly divided into five groups; Leu (n = 10), Ilue (n = 10), Val (n = 10), BCAA (n = 10), and placebo (n = 10). The muscle damage protocol specific to non-athletes is used in the current study. A 500 ml of group-specific solution was given to each group in two time points, 30 minutes before and immediately after performing the exercise. Multivariate analysis showed significant time differences for LDH in all groups (p<0.05); there were significant multivariate time differences in all groups regarding creatine kinase (CK) (p=0.000 for all groups). A significant time differences observed in all groups regarding repetition maximum [RM] (p<0.01) and pain (p=0.000 for all groups). The results of this investigation show that compared to combined BCAA, Ilue or Val; Leu provides more protective effect on attenuating the immediate increase in biochemical markers of muscle damage following eccentric-based resistance exercise, while combined BCAA may aid to maintain the range of motion. Additionally the results showed that perceived pain by individuals in the placebo group was significantly higher compared to all other groups. Hence, BCAA intake, especially Leu, in the dosage used in this investigation is ergogenic for untrained males.
本研究的目的是确定和比较亮氨酸(Leu)、缬氨酸(Val)、异亮氨酸(Ilue)和联合支链氨基酸(BCAA)补充剂对阻力运动后肌肉损伤标志物的影响。据推测,补充剂可以减轻运动引起的肌肉损伤后间接肌肉损伤标志物和肌肉酸痛的水平,并促进肌肉功能的恢复。50只未经训练的雄性被随机分为五组;Leu (n = 10)、Ilue (n = 10)、Val (n = 10)、BCAA (n = 10)和安慰剂(n = 10)。在目前的研究中使用了针对非运动员的肌肉损伤方案。每组在运动前30分钟和运动后立即两个时间点给予500 ml组特异性溶液。多因素分析显示,各组LDH时间差异有统计学意义(p<0.05);各组肌酸激酶(CK)有显著的多变量时间差异(p=0.000)。各组在最大重复次数[RM] (p<0.01)和疼痛(p=0.000)方面的时间差异均有统计学意义。本研究结果表明,与联合BCAA相比,Ilue或Val;亮氨酸提供了更多的保护作用,以减轻离心阻力运动后肌肉损伤的生化标志物的立即增加,而联合BCAA可能有助于保持运动范围。此外,结果显示,安慰剂组的个体感知疼痛明显高于其他所有组。因此,在本研究中使用的剂量中,支链氨基酸的摄入量,特别是亮氨酸,对于未经训练的雄性来说是人体所需的。
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引用次数: 3
The effect of enteral nutrition support on muscle function capacity and pulmonary functions in malnourished patients with Chronic Obstructive Pulmonary Disease 肠内营养支持对慢性阻塞性肺疾病营养不良患者肌肉功能和肺功能的影响
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-03-02 DOI: 10.23751/PN.V20I1.6043
Duygu Değirmenci, H. Şahin, M. Soylu
Patients with Chronic Obstructive Pulmonary Disease (COPD) usually have a decreased muscle function capacity and pulmonary functions. The purpose of this study was to determine the effect of enteral nutrition support given in addition to diet on muscle function capacity, forced expiratory volume in second (FEV1) and tiffeneau index (FEV1/FVC) in malnourished patient with COPD. Forty patients with body mass indexes (BMI) below 18.5 kg/m2 were included in the study. Nutrition education was given to all patients then the patients were divided into two groups as treatment and control. Treatment group consumed two bottles of enteral nutrition product in addition to oral nutrition for three months. The muscle powers of the patients were measured with handgrip dynamometer and their FEV1 and FVC values were determined with pulmonary function tests, and tiffeneau indexes were calculated in the beginning and at the end of the study. In conclusion, enteral nutrition support increased hand grip strength and FEV1 without any significant effect on FEV1/FVC values in malnourished patients with COPD.
慢性阻塞性肺疾病(COPD)患者通常有肌肉功能容量和肺功能下降。本研究的目的是确定除饮食外给予肠内营养支持对慢性阻塞性肺病营养不良患者肌肉功能容量、秒用力呼气量(FEV1)和蒂菲诺指数(FEV1/FVC)的影响。40例体重指数(BMI)低于18.5 kg/m2的患者纳入研究。对所有患者进行营养教育,并将患者分为治疗组和对照组。治疗组患者在口服营养的基础上口服肠内营养品2瓶,持续3个月。用握力计测定患者的肌力,用肺功能试验测定患者的FEV1和FVC值,并在研究开始和结束时计算蒂菲诺指数。综上所述,肠内营养支持增加了慢性阻塞性肺病营养不良患者的握力和FEV1,但对FEV1/FVC值没有显著影响。
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引用次数: 1
Assessment of nutrition and nutritional status in women using the high-protein diet in the past 过去使用高蛋白饮食的妇女的营养和营养状况评估
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-02-23 DOI: 10.23751/PN.V20I2.6370
J. Reguła, Roksana Jurczak, J. Wyka, S. Baczyńska
Background. High-protein diets are often used as a quick and easy way to achieve weight loss in those who are overweight or obese. People using for a long time this type of diet are not aware that it can cause serious health problems, therefore it is very important to monitor the effects of long-term use of high-protein diets. Aim. The aim of this study was to evaluate the high–protein diet (Dukan Diet) and after its completion, as well as to assess the nutritional status of women on the basis of biochemical parameters of blood: morphology, blood sugar, lipid profile and hepatic profile, in order to determine the health consequences of the high-protein diet. Material and Methods. The study included 32 women aged 19 to 56, who had followed the Dukan Diet in the past (2 year ago). A 7-day nutrition diary was used to assess nutrition after the Dukan Diet, where 5 days were working days and 2 days were non-working days. Nutritional status was assessed on the basis of anthropometric measurements and the morphological and biochemical parameters of blood: blood count, fasting blood glucose levels, lipid profile, the profile of the hepatic were analyzed in an accredited analytical laboratory, and these values were determined using  haematological and biochemical indicators measured on an Analyzer at Sysmex K-1000 and Vitalab Flexor, respectively. Results. The resulting analysis shows that women did not receive adequate amounts of energy from the diets. Diets were deficient in terms of most nutrients, while in other cases the values exceeded the recommended standards. Analysis has shown that the Dukan Diet is deficient in many vitamins, including vitamins C and B, nor does this diet provide a sufficient amount of dietary fiber. It has been observed of minerals deficiency (iron, magnesium, copper) both during and after the protein diet. Moreover, subjects revealed an increased concentration of eosinophils, basophils, monocytes, triglycerides, LDL cholesterol, glucose in the blood. Conclusions. The diet of women after the end of high-protein diet is still abnormal as evidenced by improper blood chemistry markers. Women should be under the control of a dietitian.
背景高蛋白饮食通常被用作超重或肥胖者减肥的一种快速简便的方法。长期使用这种饮食的人没有意识到它会导致严重的健康问题,因此监测长期使用高蛋白饮食的影响非常重要。目标本研究的目的是评估高蛋白饮食(杜坎饮食)及其完成后的营养状况,并根据血液的生化参数:形态、血糖、脂质状况和肝脏状况来评估女性的营养状态,以确定高蛋白饮食对健康的影响。材料和方法。这项研究包括32名年龄在19岁至56岁之间的女性,她们在过去(2年前)遵循杜坎饮食。使用7天营养日记评估杜坎饮食后的营养状况,其中5天为工作日,2天为非工作日。营养状况是根据人体测量和血液的形态和生化参数进行评估的:血细胞计数、空腹血糖水平、脂质状况、肝脏状况在认可的分析实验室进行分析,并且使用分别在Sysmex K-1000和Vitalab Flexor的分析仪上测量的血液学和生物化学指标来确定这些值。后果由此得出的分析表明,女性没有从饮食中获得足够的能量。饮食中的大多数营养素都不足,而在其他情况下,这些营养素的含量超过了推荐标准。分析表明,杜坎饮食缺乏许多维生素,包括维生素C和维生素B,这种饮食也没有提供足够的膳食纤维。在蛋白质饮食期间和之后都观察到矿物质缺乏(铁、镁、铜)。此外,受试者发现血液中嗜酸性粒细胞、嗜碱性粒细胞、单核细胞、甘油三酯、低密度脂蛋白胆固醇和葡萄糖的浓度增加。结论。高蛋白饮食结束后,女性的饮食仍然不正常,血液化学标志物不当就是明证。女性应该在营养师的控制下。
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引用次数: 1
Influences of Physalis peruviana L. and Lupinus albus L. fruits extracts on the levels of some biochemical parameters in brain and muscle tissues of type II diabetic rats 紫Physalis L.和Lupinus albus L.果实提取物对II型糖尿病大鼠脑和肌肉组织生化指标的影响
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-02-19 DOI: 10.23751/PN.V20I1-S.6047
O. A. Kireçci, F. Erman, A. D. Ozsahin, O. Erman, Tubay Kaya, Ö. Yılmaz
New functional foods are increasingly sought to improve the treatment of diseases related to glucose and lipid metabolism. The present study was designed to investigate the possible antidiabetic and antioxidant effects of goldenberry and lupin on brain and muscle tissues of streptozotocin-induced type II diabetic rats. Type II diabetes was produced in albino rats by the streptozotocin injection. Wistar albino rats were divided into four groups, each one containing 10 rats: non-diabetic control group, STZ- type II Diabetes group, STZ- type II Diabetes+goldenberry group, and STZ- type II Diabetes+lupin group. After one week from the injection, goldenberry and lupin were injected to rats for 2 months. Malondialdehyde, glutathione, cholesterol, and fatty acid levels, which are signs of lipid peroxidation, were measured in brain and muscle tissues. In type II diabetes, malondialdehyde increased compared to the control group. Glutathione decreased in the both tissues and all of the streptozotocin-induced diabetic groups. In type II diabetes, brain cholesterol levels decreased. Treatment with similar doses of goldenberry and lupin significantly reduced oxidative stress, augments antioxidant system and altered fatty acid metabolism in these tissues, thereby maintaining favourable fatty acid distribution affected by diabetic complications. These results validate the use of goldenberry and lupin fruits as a treatment against diabetes mellitus and its complications and suggest it is suitable to continue studies for its safe therapeutic use.
人们越来越多地寻求新的功能性食品来改善与葡萄糖和脂质代谢相关的疾病的治疗。本研究旨在研究金浆果和羽扇豆对链脲佐菌素诱导的II型糖尿病大鼠大脑和肌肉组织可能的抗糖尿病和抗氧化作用。注射链脲佐菌素在白化大鼠中产生II型糖尿病。Wistar白化大鼠分为四组,每组10只:非糖尿病对照组、STZ-Ⅱ型糖尿病组、STZ-Ⅱ型糖尿病+goldenberry组和STZ-II型糖尿病+lupin组。注射一周后,给大鼠注射goldenberry和羽扇豆素,持续2个月。在大脑和肌肉组织中测量了丙二醛、谷胱甘肽、胆固醇和脂肪酸水平,这是脂质过氧化的迹象。在II型糖尿病中,与对照组相比,丙二醛增加。谷胱甘肽在两种组织和链脲佐菌素诱导的所有糖尿病组中均降低。在II型糖尿病中,大脑胆固醇水平下降。用类似剂量的金浆果和羽扇豆进行治疗可显著降低氧化应激,增强抗氧化系统,改变这些组织中的脂肪酸代谢,从而保持受糖尿病并发症影响的有利脂肪酸分布。这些结果验证了金浆果和羽扇豆果实作为治疗糖尿病及其并发症的用途,并表明其安全的治疗用途适合继续研究。
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引用次数: 1
Assessment of eating attitudes and body satisfaction among high school adolescents in Turkey 土耳其高中青少年饮食态度与身体满意度之评估
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-02-19 DOI: 10.23751/PN.V20I2.6332
E. Bulduk, Sıdıka Bulduk, Güler Özkula
Background/aims:  This research aimed to investigate the relationship between eating attitudes and body satisfaction among adolescents attending high school in Ankara, the capital city of Turkey. Methods: The participants were 718 males and 761 females, in total 1479 adolescents aged between 13 and 18 years. The Eating Attitude Test-26 (EAT-26) and Body Cathexis Scale (BCS) were used to assess eating attitudes and body satisfaction respectively. Data from the study were evaluated statistically by chi-square test. Results: Our results showed that 2.93 % of males and 40.07 of females faced a high risk of having an eating disorder. Our findings confirm that females are more at risk of eating disorders. The BCS of males (90.8 ± 20.8) was found significantly higher than females (81.3 ± 16.8) ( p<0.001), which indicates that females are less content than about their appearance. We also found that 6.3 % of males and 18.2 % of females thought that they were overweight, and 22.9% of females and 4.3 % of males perceived themselves as obese. While 58.6 % of males perceived their body image as correct, 65.8 % of females did not (p<0.05). Conclusion: Together these results confirm that female adolescents tend to be less satisfied with their weight and more likely to display disordered eating attitudes.   Keywords: Adolescents, Eating Attitude Test-26, Body Cathexis Scale, Body Satisfaction
背景/目的:本研究旨在调查土耳其首都安卡拉高中生的饮食态度与身体满意度之间的关系。方法:参与者为718名男性和761名女性,共1479名年龄在13至18岁之间的青少年。饮食态度测试-26(EAT-26)和身体导尿管量表(BCS)分别用于评估饮食态度和身体满意度。通过卡方检验对研究数据进行统计学评价。结果:我们的研究结果显示,2.93%的男性和40.07%的女性面临饮食失调的高风险。我们的研究结果证实,女性患饮食失调的风险更大。男性的BCS(90.8±20.8)显著高于女性(81.3±16.8)(p<0.001),这表明女性对自己的外表不太满意。我们还发现,6.3%的男性和18.2%的女性认为自己超重,22.9%的女性和4.3%的男性认为自己肥胖。58.6%的男性认为自己的身体形象是正确的,而65.8%的女性则不然(p<0.05)。结论:这些结果共同证实,女性青少年往往对自己的体重不太满意,更有可能表现出紊乱的饮食态度。关键词:青少年,饮食态度测试-26,身体导管量表,身体满意度
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引用次数: 1
The effects of oral nutritional formula enriched with arginine, omega 3 fatty acids and nucleotides on methotrexate-induced experimental intestinal mucositis 富含精氨酸、ω3脂肪酸和核苷酸的口服营养配方对甲氨蝶呤诱导的实验性肠粘膜炎的影响
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-02-16 DOI: 10.23751/PN.V20I2.6396
E. Akyuz, Cebrail Akyüz, G. Kiziltan, A. Sehirli, Ş. Çetinel
The aim of this study to investigate the effect of an immunonutritional (IN) oral formula enriched with arginine, omega-3 fatty acids and nucleotides in methotrexate (MTX)-induced experimental intestinal mucositis model. In the study, 32 rats were divided into four groups consisting eight animals in each. Control group fed for 5 days with only saline with gavage, IN group fed for 5 days with an oral IN formula three times a day, MTX group with an intraperitoneal single dose MTX (20 mg/kg), followed by saline with gavage, MTX-IN group with a single dose of MTX, followed by an oral IN formula three times a day. The blood and jejunal tissue sample were collected and then the rats were sacrificed on the sixth day of the study. The level of TNF-α, IL-1β in serum, luminol, lusigenin, glutathione, myeloperoxidase, malondialdehyde and Na-K+ATPase in the jejunal tissue samples were analyzed. Histopathological examination was performed in the jejunal tissue samples. In the MTX group, TNF-α, IL-1β levels in serum, and luminol, lusigenin, malondialdehyde levels, and myeloperoxidase activity in tissue samples were found significantly higher than the control group. Glutathione and Na-K+ATPase levels were lower in the jejunal tissue of the MTX group compared to control group. However, the supplementation of IN with the MTX resulted in a significant increase in glutathione and Na-K+ATPase levels. Severe epithelium loss and inflammatory cell increase were observed in the MTX group on histological examination, whereas these parameters were regressed in the MTX-IN group. Increasing in the mitosis rate of enterocytes and inflammatory cell density decreased with the IN. In conclusion, this study shows that chemotherapy has adverse effects on intestinal mucosa and the IN formula has a protective effect of on MTX-associated intestinal damage.
本研究旨在探讨富含精氨酸、omega-3脂肪酸和核苷酸的免疫营养(IN)口服配方对甲氨蝶呤(MTX)诱导的实验性肠黏膜炎模型的影响。在这项研究中,32只大鼠被分为四组,每组8只。对照组只灌胃生理盐水5 d, IN组灌胃生理盐水3次,MTX组腹腔注射单剂量MTX (20 mg/kg),再灌胃生理盐水,MTX-IN组灌胃单剂量MTX,再灌胃生理盐水3次,MTX-IN组灌胃单剂量MTX,再灌胃生理盐水3次。取血液和空肠组织标本,于实验第6天处死大鼠。分析血清中TNF-α、IL-1β、鲁米诺、葡黄素、谷胱甘肽、髓过氧化物酶、丙二醛和空肠组织Na-K+ atp酶的水平。空肠组织标本行组织病理学检查。MTX组血清中TNF-α、IL-1β水平,组织样品中鲁米诺、葡黄素、丙二醛水平和髓过氧化物酶活性均显著高于对照组。MTX组空肠组织谷胱甘肽和Na-K+ atp酶水平低于对照组。然而,在MTX中补充IN导致谷胱甘肽和Na-K+ atp酶水平显著增加。MTX组在组织学检查中观察到严重的上皮丢失和炎症细胞增加,而MTX- in组这些参数是回归的。肠细胞有丝分裂率升高,炎症细胞密度随素的增加而降低。综上所述,本研究表明化疗对肠黏膜有不良影响,而In方对mtx相关肠道损伤具有保护作用。
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引用次数: 3
Addition of sesamum indicum protein isolates improves the nutritional quality and sensorial attributes of wheat flour muffins 添加芝麻分离蛋白可改善小麦松饼的营养品质和感官特性
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-02-15 DOI: 10.23751/PN.V20I2.6363
Muhammad Sibt-e-Abbas, M. S. Butt, M. Khan, M. Shahid
In the present research, efforts were made to enhance protein content of muffins using non-conventional protein sources. In this context, wheat flour was enriched with varying levels (5, 10, 15, 20 and 25%) of sesame protein isolates (SPI). Flour blends were used to prepare protein enriched muffins that were further evaluated for chemical composition, gross energy, color & textural analysis, and sensorial appraisal. The results were quite conclusive that nutritional quality of the muffins was improved with addition of SPI. Moreover, color analysis showed decreasing trend for L* & b* value, chroma and hue angle, while increasing trend was noticed for a* value. Likewise, the texture profile of muffins showed that firmness increased while elasticity decreased with gradual increase in protein contents. Sensory evaluation showed that muffins containing 15% SPI were rated better by the trained panelists. Conclusively, owing to high nutritive value and balanced nutritional profile, the use of sesame protein isolates can be handy tool to improve the nutritional quality of wheat based bakery products. These protein enriched products i.e. muffins can also help to fulfill the nutritional requirements of masses especially in developing countries.
在目前的研究中,人们努力使用非传统的蛋白质来源来提高松饼的蛋白质含量。在这种情况下,小麦面粉富含不同水平(5%、10%、15%、20%和25%)的芝麻分离蛋白(SPI)。混合面粉用于制备富含蛋白质的松饼,并对其化学成分、总能量、颜色和质地分析以及感官评估进行了进一步评估。研究结果表明,添加SPI能显著提高松饼的营养品质。此外,颜色分析显示L*&b*值、色度和色调角呈下降趋势,而a*值呈上升趋势。同样,松饼的质地特征表明,随着蛋白质含量的逐渐增加,硬度增加,而弹性降低。感官评估显示,经过培训的小组成员对含有15%SPI的松饼的评价更好。总之,由于芝麻分离蛋白具有较高的营养价值和均衡的营养成分,因此使用芝麻分离蛋白可以方便地提高小麦烘焙产品的营养质量。这些富含蛋白质的产品,即松饼,也有助于满足大众的营养需求,尤其是在发展中国家。
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引用次数: 2
Self-efficacy and cues to action: Two main predictors of modified version of diet quality index in Iranian adolescents 自我效能感和行动提示:伊朗青少年改良版饮食质量指数的两个主要预测因子
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-02-08 DOI: 10.23751/PN.V20I2.6711
P. Keshani, M. Salehi, M. Kaveh, S. Faghih
Background: The purpose of this study was to examine the association between health belief model (HBM) constructs and a modified version of diet quality index in Iranian adolescents. Methods: One thousand and fifty five adolescents aged 13-15 years old completed this cross-sectional study. Participants were selected from secondary schools in Shiraz, one of the megacities of Iran, using stratified random sampling. A modified version of revised children’s diet quality index (M-RCDQI), was calculated for each adolescents and its association with the model construct was assessed using linear regression. Results: Mean M-RCDQI score was 58.91±8.58 out of the total of 90 points. Among the M-RCDQI components, the worse scores were obtained by dairy intake, dietary fiber and vegetables in which less than 20% of the students reached maximum score. Among HBM constructs, cues to action (B=0.194, p=0.003) and self-efficacy (B=0.04, p=0.007) had positive, significant association with adolescents’ diet quality. Also there was a positive, significant association between cues to action and fruits consumption (B=0.026, P=0.026), and a negative significant association was seen between cues to action and total fat intake (B=-0.629, p=0.021). Furthermore, self-efficacy had a direct significant association with dairy intake. Conclusion: M-RCDQI could be a suitable tool for assessment of diet quality index and it is recommended for use in further studies in similar populations. Cues to action and self-efficacy would both be effective mediators in improvement of nutritional behavior among adolescents.
背景:本研究的目的是检验伊朗青少年的健康信念模型(HBM)结构与改良版饮食质量指数之间的关系。方法:一百五十五名13-15岁的青少年完成了这项横断面研究。参与者是从伊朗特大城市之一设拉子的中学中选择的,采用分层随机抽样。计算每个青少年的修订版儿童饮食质量指数(M-RCDQI),并使用线性回归评估其与模型构建的相关性。结果:90分中M-RCDQI平均得分为58.91±8.58分。在M-RCDQI成分中,乳制品摄入、膳食纤维和蔬菜得分最差,其中只有不到20%的学生达到最高得分。在HBM结构中,行动线索(B=0.194,p=0.003)和自我效能感(B=0.04,p=0.007)与青少年的饮食质量呈正相关。此外,行动提示与水果消费之间存在正相关(P=0.026,P=0.026),行动提示和总脂肪摄入量之间存在负相关(B=-0.629,P=0.021)。此外,自我效能感与乳制品摄入量有直接显著关联。结论:M-RCDQI可作为评估膳食质量指数的一种合适的工具,建议在类似人群的进一步研究中使用。行动提示和自我效能都是改善青少年营养行为的有效中介。
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引用次数: 4
The Relation Between Meal Frequency and Obesity in Adults 成人进餐频率与肥胖的关系
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-01-01 DOI: 10.23751/PN.V20I3.7175
Selen Müftüoğlu, Merve Özdemir, Mendane Saka, M. Ok, Esra Köseler, Sinem Bayram, Esen Yeşil, Beril Köse, P. Türker, A. Ercan, E. Aksoydan, M. Tayfur, G. Kiziltan
Obesity is one of the most common nutritional disorders. Some studies suggest that obesity may be related to eating patterns, such as meal frequency, temporal distribution of eating events during the day, meal skipping and the frequency of out of meals. Therefore, in this cross-sectional study was investigated the relationships between meal frequency, anthropometric measurements, energy-macro/micronutrient intakes and meal skipping frequency for 1829 volunteer (520 men, 1309 women) adults aged between 40 and 64 years old, from Ankara, Turkey. The median meal frequency of women and men were 4 and 3, respectively. Approximately 57% of men and 61% of women have skipped meals and 76.8% of them were skipped their lunch. The meal frequency positively correlated with waist/ hip ratio in women (p<0.05). Additionally, there were positively significant correlations between meal frequency and saturated fatty acids, fiber, vitamin A, tiamine, riboflavin, folate, vitamin B6, vitamin C, calcium, magnesium, iron and copper intake (p<0.05). As a conclusion, the data indicate that increased meal frequency may have a beneficial effect on micronutrients intakes and some anthropometric measurements among adults.
肥胖是最常见的营养失调之一。一些研究表明,肥胖可能与饮食模式有关,比如吃饭频率、一天中吃饭事件的时间分布、不吃饭和不吃饭的频率。因此,在这项横断面研究中,研究人员调查了来自土耳其安卡拉的1829名志愿者(520名男性,1309名女性)年龄在40至64岁之间的进餐频率、人体测量值、能量宏量/微量营养素摄入量和不吃饭频率之间的关系。女性和男性的用餐频率中位数分别为4次和3次。大约57%的男性和61%的女性不吃正餐,其中76.8%的人不吃午餐。女性进餐频率与腰臀比呈正相关(p<0.05)。此外,摄食频率与饱和脂肪酸、纤维、维生素A、维生素胺、核黄素、叶酸、维生素B6、维生素C、钙、镁、铁、铜摄入量呈显著正相关(p<0.05)。综上所述,数据表明,增加进餐频率可能对成年人的微量营养素摄入量和一些人体测量值有有益的影响。
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引用次数: 1
Effects of probiotic soy milk on lipid panel in type 2 diabetic patients with nephropathy: A double-blind randomized clinical trial 益生菌豆浆对2型糖尿病肾病患者脂质面板的影响:一项双盲随机临床试验
4区 医学 Q4 Agricultural and Biological Sciences Pub Date : 2018-01-01 DOI: 10.23751/PN.V20I2-S.5342
B. Abbasi, M. Mirlohi, M. Daniali, R. Ghiasvand
Background: Cardiovascular diseases (CVD) are among the most common complications of diabetes. Lipid abnormalities in diabetic patients are not only related to higher risk of CVD, but also accelerate the progression of diabetic nephropathy. To the best of our knowledge, there is no study that has assessed the effects of probiotic soy milk on lipid profile in type 2 diabetic patients with nephropathy. Objective: The current study was designed to examine the effects of consumption of soy milk containing lactobacillus plantarum A7 compared with conventional soy milk on lipid panel in type 2 diabetic patients with nephropathy. Methods: A total of 44 type 2 diabetic patients with nephropathy were randomly assigned to receive 200 ml/day of either probiotic soy milk (n=22) or conventional soy milk (n=22) for eight weeks, in this randomized double-blind clinical trial. Fasting blood samples were taken at the beginning and after eight weeks of the intervention for analysis of lipid profile and other relevant variables. P values < 0.05 were considered as statistically significant. Results: Consumption of probiotic soy milk for 8 weeks led to an increase in serum genistein (17.6±15.3 vs. 4.5±2.3, p=0.002) and eGFR (15.9±10.8 vs. 3.2±8.4, p<0.001) compared with conventional soy milk. Additionally probiotic soy milk resulted in decreased LDL-cholesterol (-9.2±10.4 vs. -2.2±5.2, p=0.01), total cholesterol (-12.4±4.8 vs. -4.87±14.7, p=0.04), non-HDL cholesterol (-15.3±4.5 vs. -5.9±14.7, p=0.01) and serum TG (-14.6±12.5 vs. -3.9±9.3, p=0.007) compared with control group. We did not detect any significant effect of probiotic soy milk on serum HDL-cholestrol (1.11±3.38 vs. 0.90±2.7, p=0.8) and serum phosphorus (-0.14±0.10 vs. 0.05±0.5, p=0.1). Conclusion: Administration of soy milk containing lactobacillus plantarum A7 in type 2 diabetic patients with nephropathy had beneficial effects on lipid profile and glomerular function, but did not affect HDL-cholesterol. In addition probiotic soy milk did not result in a significant elevation in the serum phosphorus concentration. This trial was registered at http://www.irct.ir as IRCT201601027479N2.
背景:心血管疾病是糖尿病最常见的并发症之一。糖尿病患者血脂异常不仅与CVD发生风险增高有关,而且还会加速糖尿病肾病的进展。据我们所知,目前还没有研究评估益生菌豆浆对2型糖尿病肾病患者血脂的影响。目的:本研究旨在比较食用含有植物乳杆菌A7的豆浆与普通豆浆对2型糖尿病肾病患者脂质面板的影响。方法:在随机双盲临床试验中,44例2型糖尿病肾病患者被随机分配为200 ml/天的益生菌豆浆(n=22)或常规豆浆(n=22),为期8周。在干预开始时和干预八周后采集空腹血样,分析血脂和其他相关变量。P值< 0.05认为有统计学意义。结果:与常规豆浆相比,饮用益生菌豆浆8周后血清染料木素(17.6±15.3比4.5±2.3,p=0.002)和eGFR(15.9±10.8比3.2±8.4,p<0.001)升高。此外,与对照组相比,益生菌豆浆降低了低密度脂蛋白胆固醇(-9.2±10.4比-2.2±5.2,p=0.01)、总胆固醇(-12.4±4.8比-4.87±14.7,p=0.04)、非高密度脂蛋白胆固醇(-15.3±4.5比-5.9±14.7,p=0.01)和血清TG(-14.6±12.5比-3.9±9.3,p=0.007)。我们未发现益生菌豆浆对血清高密度脂蛋白胆固醇(1.11±3.38 vs 0.90±2.7,p=0.8)和血清磷(-0.14±0.10 vs 0.05±0.5,p=0.1)有显著影响。结论:2型糖尿病肾病患者服用植物乳杆菌A7豆浆对其血脂和肾小球功能有改善作用,但对hdl -胆固醇无影响。此外,益生菌豆浆没有导致血清磷浓度的显著升高。该试验在http://www.irct.ir注册,注册号为IRCT201601027479N2。
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引用次数: 11
期刊
Progress in Nutrition
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