Pub Date : 2022-03-09DOI: 10.46991/pysu:b/2022.56.1.010
A. K. Dovlatyan, H. Badalyan, L. Harutyunyan, R. Harutyunyan
The computer modeling of complexes of pyridinium peroxodisulfates (СnPyr)2S2O8, where n=8; 12; 15; 16; 18; 20, have been done. The structural and energetic parameters of complexes (СnPyr)2S2O8 have been calculated by molecular-dynamic at 300 K and semi-empirical quantum-chemical methods. The values of geometric and energetic parameters of optimized complexes (СnPyr)2S2O8 in vacuum and in aqueous medium, and the results of total energy quantum-chemical calculations are given. It has been established that the length of alkyl chain significantly effects on electrostatic interactions and energetically more beneficial formation of a complex with alkyl chain length n=16.
{"title":"QUANTUM-CHEMICAL SIMULATION OF PYRIDINIUM PEROXODISULFATES (С$_n$Pyr)$_2$S$_2$O$_8$ COMPLEXES","authors":"A. K. Dovlatyan, H. Badalyan, L. Harutyunyan, R. Harutyunyan","doi":"10.46991/pysu:b/2022.56.1.010","DOIUrl":"https://doi.org/10.46991/pysu:b/2022.56.1.010","url":null,"abstract":"The computer modeling of complexes of pyridinium peroxodisulfates (СnPyr)2S2O8, where n=8; 12; 15; 16; 18; 20, have been done. The structural and energetic parameters of complexes (СnPyr)2S2O8 have been calculated by molecular-dynamic at 300 K and semi-empirical quantum-chemical methods. The values of geometric and energetic parameters of optimized complexes (СnPyr)2S2O8 in vacuum and in aqueous medium, and the results of total energy quantum-chemical calculations are given. It has been established that the length of alkyl chain significantly effects on electrostatic interactions and energetically more beneficial formation of a complex with alkyl chain length n=16.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77958339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-09DOI: 10.46991/pysu:b/2022.56.1.031
Ruben E. Israyelyan, T. Sargsyan
In this study an available reversed-phase HPLC method for the identification of sibutramine with UV detection and isocratic elution mode was developed, the evaluation of the method applicability and determination of validation indicators were carried out. It has been shown that the developed method meets the current international requirements. To search for sibutramine, the developed method has been used in some biologically active additives ("Lipocarnit", "Pineapple extract", "Turboslim night" and "Turboslim day").
{"title":"DEVELOPMENT OF AN HPLC METHOD FOR SIBUTRAMINE IDENTIFICATION. SEARCH FOR UNDECLARED SIBUTRAMINE IN BIOLOGICALLY ACTIVE ADDITIVES APPETITE SUPPRESSANTS","authors":"Ruben E. Israyelyan, T. Sargsyan","doi":"10.46991/pysu:b/2022.56.1.031","DOIUrl":"https://doi.org/10.46991/pysu:b/2022.56.1.031","url":null,"abstract":"In this study an available reversed-phase HPLC method for the identification of sibutramine with UV detection and isocratic elution mode was developed, the evaluation of the method applicability and determination of validation indicators were carried out. It has been shown that the developed method meets the current international requirements. To search for sibutramine, the developed method has been used in some biologically active additives (\"Lipocarnit\", \"Pineapple extract\", \"Turboslim night\" and \"Turboslim day\").","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"41 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79311054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-09DOI: 10.46991/pysu:b/2022.56.1.018
A. S. Dadayan, L. A. Stepanyan, T. Sargsyan, A. S. Poghosyan, Ella V. Minasyan, Monika H. Israyelyan, A. Hovhannisyan, S. A. Dadayan
The work is devoted to a comparative study of the physicochemical, organoleptic characteristics of oils obtained by extraction method using sunflower oil and pomace remaining after their processing in order to identify the prerequisites for further use. The study object was the seeds of wine grapes of Khindoghni and Areni (grown in the Republic of Armenia), harvest of 2019–2021. The purpose of this study was to determine the comparative indicators of the quality and content of fatty acids in grape oils by gas-liquid chromatography. The optimal conditions for obtaining high quality unrefined grape oil for the food and pharmaceutical industries from grape seeds of Khindoghni and Areni varieties by the extraction method were determined: temperature 45–50℃, at atmospheric pressure and carbon dioxide gasbag (CO2), stirring time 16 h. Under these optimal conditions the oil yield was 9.5%. It has been shown that oils from the seeds of Khindoghni and Areni grape varieties contain 1.181 mg/100 g tocopherols, 3.2 mg/100 g carotenoids, vitamins C, P, E and the pomace of their processing contains valuable free organic acids: 0.093 mg/mL oxalic, 3.105 mg/mL tartaric, 0.48 mg/mL citric. It has been shown that the content of macro- (Fe, Cu, Zn, Ca, Mg, etc.) and microelements (Mn, Co, Cd, V, Se, Cr, As, Pb, etc.) in the seeds of the studied samples are within permissible limits. On the basis of the research carried out, a scheme for the complex processing of grape raw materials has been developed.
{"title":"STUDY OF OIL AND POMACE FROM GRAPE SEEDS FOR THE IDENTIFICATION OF PREREQUISITES OF THEIR COMPLEX PROCESSING","authors":"A. S. Dadayan, L. A. Stepanyan, T. Sargsyan, A. S. Poghosyan, Ella V. Minasyan, Monika H. Israyelyan, A. Hovhannisyan, S. A. Dadayan","doi":"10.46991/pysu:b/2022.56.1.018","DOIUrl":"https://doi.org/10.46991/pysu:b/2022.56.1.018","url":null,"abstract":"The work is devoted to a comparative study of the physicochemical, organoleptic characteristics of oils obtained by extraction method using sunflower oil and pomace remaining after their processing in order to identify the prerequisites for further use. The study object was the seeds of wine grapes of Khindoghni and Areni (grown in the Republic of Armenia), harvest of 2019–2021. The purpose of this study was to determine the comparative indicators of the quality and content of fatty acids in grape oils by gas-liquid chromatography. The optimal conditions for obtaining high quality unrefined grape oil for the food and pharmaceutical industries from grape seeds of Khindoghni and Areni varieties by the extraction method were determined: temperature 45–50℃, at atmospheric pressure and carbon dioxide gasbag (CO2), stirring time 16 h. Under these optimal conditions the oil yield was 9.5%. It has been shown that oils from the seeds of Khindoghni and Areni grape varieties contain 1.181 mg/100 g tocopherols, 3.2 mg/100 g carotenoids, vitamins C, P, E and the pomace of their processing contains valuable free organic acids: 0.093 mg/mL oxalic, 3.105 mg/mL tartaric, 0.48 mg/mL citric. It has been shown that the content of macro- (Fe, Cu, Zn, Ca, Mg, etc.) and microelements (Mn, Co, Cd, V, Se, Cr, As, Pb, etc.) in the seeds of the studied samples are within permissible limits. On the basis of the research carried out, a scheme for the complex processing of grape raw materials has been developed.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90679994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-09DOI: 10.46991/pysu:b/2022.56.1.001
S. Hayrapetyan, Mikael S. Chobanyan, Vahe A. Hovhannisyan, L. S. Banyan, H. H. Khachatryan
The structure-forming properties of mineral conditioners caused by acidic treatment have been studied by means of turbidimetry as well as particles size distribution methods. Three types of mineral conditioner having СаО, SO42– and РO43– groups on the surface have been investigated. The first two types were treated with nitric acid, and the third with phosphoric acid. The treatment of mineral conditioners with phosphoric acid causes a decrease in the effluent turbidity, whereas when treating СаО group containing mineral conditioner with nitric acid a sharp increase in this parameter is observed. When treating sulfo group mineral conditioner this increase is not significant.
{"title":"THE INFLUENCE OF ACIDIC TREATMENT OF MINERAL CONDITIONERS ON THEIR STRUCTURE-FORMING PROPERTIES","authors":"S. Hayrapetyan, Mikael S. Chobanyan, Vahe A. Hovhannisyan, L. S. Banyan, H. H. Khachatryan","doi":"10.46991/pysu:b/2022.56.1.001","DOIUrl":"https://doi.org/10.46991/pysu:b/2022.56.1.001","url":null,"abstract":"The structure-forming properties of mineral conditioners caused by acidic treatment have been studied by means of turbidimetry as well as particles size distribution methods. Three types of mineral conditioner having СаО, SO42– and РO43– groups on the surface have been investigated. The first two types were treated with nitric acid, and the third with phosphoric acid. The treatment of mineral conditioners with phosphoric acid causes a decrease in the effluent turbidity, whereas when treating СаО group containing mineral conditioner with nitric acid a sharp increase in this parameter is observed. When treating sulfo group mineral conditioner this increase is not significant.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82688788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-09DOI: 10.46991/pysu:b/2022.56.1.041
P. Gukasyan, Sevda B. Mkhitaryan, S. M. Vardapetyan, V. Sarkeziyan, O. A. Kamalyan
The textural and catalytic characteristics of the surface of silica gel modified with zinc oxide by the sol-gel method and by means of a chemical transport reaction (CTR) have been studied. It was found that catalytic activity of the obtained contacts depends on both the nature and the structural and textural characteristics of the supported ZnO. Using the example of the reaction of low-temperature oxidation of propane, it was found that lower limit of the release of radicals from the surface into the volume with the CTR modification method is lower by 15–20 degrees than in the case of the sol-gel method. It was shown that the catalyst obtained by applying the active phase on the surface of the support by the CTR method is more efficient due to the energy homogeneity of its active centers and the texture characteristics of the surface.
{"title":"TEXTURAL AND CATALYTIC FEATURES OF SILICON SURFACE MODIFIED WITH ZnO IN THE REACTION OF HOMOGENOUS-HETEROGENEOUS ACTIVATION OF PROPANE-OXYGEN MIXTURES AT LOW PRESSURES","authors":"P. Gukasyan, Sevda B. Mkhitaryan, S. M. Vardapetyan, V. Sarkeziyan, O. A. Kamalyan","doi":"10.46991/pysu:b/2022.56.1.041","DOIUrl":"https://doi.org/10.46991/pysu:b/2022.56.1.041","url":null,"abstract":"The textural and catalytic characteristics of the surface of silica gel modified with zinc oxide by the sol-gel method and by means of a chemical transport reaction (CTR) have been studied. It was found that catalytic activity of the obtained contacts depends on both the nature and the structural and textural characteristics of the supported ZnO. Using the example of the reaction of low-temperature oxidation of propane, it was found that lower limit of the release of radicals from the surface into the volume with the CTR modification method is lower by 15–20 degrees than in the case of the sol-gel method. It was shown that the catalyst obtained by applying the active phase on the surface of the support by the CTR method is more efficient due to the energy homogeneity of its active centers and the texture characteristics of the surface.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86384197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-23DOI: 10.46991/pysu:b/2021.55.3.266
S. Nanagulyan, L. Margaryan, Yeva Kh. Hovhannisyan, Iren V. Shahazizyan
As a result of studying the biota of the agaricoid basidiomycetes of the Shikahogh State Reserve, 148 species of fungi are found, from which 97 species are edible, 48 species – poisonous and 52 species have medicinal properties. Мacromycetes have great potential for use in medicine and economy.
{"title":"USEFUL AND HARMFUL PROPERTIES OF AGARICOID BASIDIOMYCETES OF THE SHIKAHOGH STATE RESERVE","authors":"S. Nanagulyan, L. Margaryan, Yeva Kh. Hovhannisyan, Iren V. Shahazizyan","doi":"10.46991/pysu:b/2021.55.3.266","DOIUrl":"https://doi.org/10.46991/pysu:b/2021.55.3.266","url":null,"abstract":"As a result of studying the biota of the agaricoid basidiomycetes of the Shikahogh State Reserve, 148 species of fungi are found, from which 97 species are edible, 48 species – poisonous and 52 species have medicinal properties. Мacromycetes have great potential for use in medicine and economy.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90599672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-23DOI: 10.46991/pysu:b/2021.55.3.212
M. Parsadanyan, M. Mikaelyan
Skin permeability of Sevan trout has been studied during 30 min in different solutions: in distilled water, in 70% ethanol, in solution of 0.125 M KCl. The permeability was measured by methylene blue. It was shown that the skin permeability for this dye changes depending, on what solution these shreds of Sevan trout were kept and what side the shred was tightened from. It was also shown that distilled water, solution of 0.125 M KCl and ethanol result in structural changes of Sevan trout skin layers, particularly epidermis.
在不同的溶液中:蒸馏水，70%乙醇，0.125 M KCl溶液中，研究了Sevan鳟鱼30分钟的皮肤渗透性。通过亚甲基蓝测定其渗透率。结果表明，皮肤对这种染料的渗透性会发生变化，这取决于，这些塞万鳟鱼切片保存的溶液以及切片是从哪一边收紧的。蒸馏水、0.125 M KCl溶液和乙醇均可引起鳟鱼皮肤各层结构的变化，尤其是表皮结构的变化。
{"title":"STUDY OF PERMEABILITY OF FISH SKIN","authors":"M. Parsadanyan, M. Mikaelyan","doi":"10.46991/pysu:b/2021.55.3.212","DOIUrl":"https://doi.org/10.46991/pysu:b/2021.55.3.212","url":null,"abstract":"Skin permeability of Sevan trout has been studied during 30 min in different solutions: in distilled water, in 70% ethanol, in solution of 0.125 M KCl. The permeability was measured by methylene blue. It was shown that the skin permeability for this dye changes depending, on what solution these shreds of Sevan trout were kept and what side the shred was tightened from. It was also shown that distilled water, solution of 0.125 M KCl and ethanol result in structural changes of Sevan trout skin layers, particularly epidermis.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"4 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83609189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-23DOI: 10.46991/pysu:b/2021.55.3.240
Narine Hayrapetyan
The article presents experimental data on the effectiveness of drugs that could stimulate the start of metabolic adaptation during the development of methemoglobinemia. The modeling of this type of hemic hypoxia led to the disruption of antioxidant protection, resulting in a rather significant decrease of superoxide dismutase and catalase (primary antioxidant enzymes) in the blood plasma of tested animals. We have established that anti-hypoxic activity was higher with the use of mexidol compared to the use of tocopherol. The differences in the indicators can perhaps be explained by the different mechanisms of action of the used antioxidants. The state of methemoglobinemia has also led to increased concentrations of medium-size molecules in the blood plasma. The use of mexidol and tocopherol did not show any significant effect on normalization.
{"title":"THE STUDY OF THE EFFECTIVENESS OF ANTIHYPOXIC PROPERTIES OF CERTAIN COMPOUNDS OF VARIOUS ACTION MECHANISMS ON HEMIC HYPOXIA MODELS","authors":"Narine Hayrapetyan","doi":"10.46991/pysu:b/2021.55.3.240","DOIUrl":"https://doi.org/10.46991/pysu:b/2021.55.3.240","url":null,"abstract":"The article presents experimental data on the effectiveness of drugs that could stimulate the start of metabolic adaptation during the development of methemoglobinemia. The modeling of this type of hemic hypoxia led to the disruption of antioxidant protection, resulting in a rather significant decrease of superoxide dismutase and catalase (primary antioxidant enzymes) in the blood plasma of tested animals. We have established that anti-hypoxic activity was higher with the use of mexidol compared to the use of tocopherol. The differences in the indicators can perhaps be explained by the different mechanisms of action of the used antioxidants. The state of methemoglobinemia has also led to increased concentrations of medium-size molecules in the blood plasma. The use of mexidol and tocopherol did not show any significant effect on normalization.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79006292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-23DOI: 10.46991/pysu:b/2021.55.3.285
A. Mamyan, G. Gevorgyan
The phytoplankton dynamics in the Debed River, Armenia, was investigated. Water samples for phytoplankton quantitative and qualitative analyses were collected from 4 sites along the river once per season in April, July and September 2017. The results of the study have revealed the characteristics of the spatiotemporal distribution of phytoplankton community in the Debed River.
{"title":"SEASONAL AND SPATIAL DISTRIBUTION OF PHYTOPLANKTON IN ARMENIAN LOTIC ECOSYSTEMS: CASE STUDY OF THE DEBED RIVER","authors":"A. Mamyan, G. Gevorgyan","doi":"10.46991/pysu:b/2021.55.3.285","DOIUrl":"https://doi.org/10.46991/pysu:b/2021.55.3.285","url":null,"abstract":"The phytoplankton dynamics in the Debed River, Armenia, was investigated. Water samples for phytoplankton quantitative and qualitative analyses were collected from 4 sites along the river once per season in April, July and September 2017. The results of the study have revealed the characteristics of the spatiotemporal distribution of phytoplankton community in the Debed River.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74640935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-23DOI: 10.46991/pysu:b/2021.55.3.255
Anahit H. Shirvanyan, Satenik N. Mirzoyan, K. Trchounian
Saccharomyces cerevisiae is an essential component of human civilization because of its extensive use in food industry. At the point of industrial usage it is very important to get large amount of biomass but many factors causes yeast's viability loss and death. The aim of this work was to study the peculiarities of growth parameters – specific growth rate (SGR, μ, growth yield) of S. cerevisiae wine and beer strains under different external conditions, as well as pH and oxidation-reduction potential (ORP) changes during growth. It was shown that under aerobic cultivation, the conditions 30℃ and pH 6.5 are more favorable for the growth of 2 strains (ATCC 9804, μ = 0.398; ATCC 13007, μ = 0.407), where they can enhance the biomass, and under microaerobic conditions the pH 5.0 and 37℃ are more favorable (ATCC 9804, μ = 0.35; ATCC 13007, μ = 0.436). During aerobic conditions, lower ORP values are established which did not depend on growth temperature and external pH. Under microaerobic conditions until the establish¬ment of the stationary phase (24 h) pH dependent changes of ORP were established. Obtained results will help to clarify the biochemical, biophysical and bioenergetic phenomena of yeast survival that can enhance the biomass growth and yield and thus applied industrial scale.
{"title":"PECULIARITIES OF GROWTH PARAMETERS OF $SACCHAROMYCES~CEREVISIAE$ UNDER DIFFERENT CONDITIONS","authors":"Anahit H. Shirvanyan, Satenik N. Mirzoyan, K. Trchounian","doi":"10.46991/pysu:b/2021.55.3.255","DOIUrl":"https://doi.org/10.46991/pysu:b/2021.55.3.255","url":null,"abstract":"Saccharomyces cerevisiae is an essential component of human civilization because of its extensive use in food industry. At the point of industrial usage it is very important to get large amount of biomass but many factors causes yeast's viability loss and death. The aim of this work was to study the peculiarities of growth parameters – specific growth rate (SGR, μ, growth yield) of S. cerevisiae wine and beer strains under different external conditions, as well as pH and oxidation-reduction potential (ORP) changes during growth. It was shown that under aerobic cultivation, the conditions 30℃ and pH 6.5 are more favorable for the growth of 2 strains (ATCC 9804, μ = 0.398; ATCC 13007, μ = 0.407), where they can enhance the biomass, and under microaerobic conditions the pH 5.0 and 37℃ are more favorable (ATCC 9804, μ = 0.35; ATCC 13007, μ = 0.436). During aerobic conditions, lower ORP values are established which did not depend on growth temperature and external pH. Under microaerobic conditions until the establish¬ment of the stationary phase (24 h) pH dependent changes of ORP were established. Obtained results will help to clarify the biochemical, biophysical and bioenergetic phenomena of yeast survival that can enhance the biomass growth and yield and thus applied industrial scale.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76837336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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