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Unlocking the Impact of Renal Function on Acute Coronary Syndrome: Insights from A Cohort Of 318 Cases 揭示肾功能对急性冠状动脉综合征的影响:从 318 例队列中获得的启示
Pub Date : 2024-03-15 DOI: 10.47191/rajar/v10i03.01
Hanaa El Ghiati, Hind Ouaouicha, Hamza Chraibi, Z. F. Fehri, N. Mouine, Z. Lakhal, A. Benyass
Introduction: Chronic kidney disease (CKD) represents a distinct risk factor by itself for the development of coronary artery disease (CAD). Notably, CAD stands as the primary driver of both sickness and death among individuals diagnosed with CKD. Furthermore, individuals with CKD tend to experience worse outcomes when it comes to CAD. In addition to conventional risk factors, numerous factors associated with uremia, including inflammation, oxidative stress, endothelial dysfunction, coronary artery calcification, elevated homocysteine levels, and the use of immunosuppressants, have been linked to an increased risk of accelerated atherosclerosis. Objective and method: In this study, we aim to assess the differential effect of renal impairment across the spectrum of patients with acute coronary syndrom. We conducted this study in the intensive care unit of cardiology in the Military Teaching Hospital of Rabat. Results: A total of 318 patients were included in the study. The average age was 63.8 +/- 9.41 years and 77% (244/318) were male. Normal kidney function was reported in 72.8% (220/318) of patients. Of the 318 included patients, 121(38.3%) were presented with STEMI, 154 (48.7%) with NSTEMI, and 41 (13%) with unstable angina. The difference of age was significant with a p-value of <.001 with a mean of age of 61.8 in patients with normal renal function vs 68.1 in impaired renal function patients. Patients with impaired GFR had more history of previous PCI (21) compared to those with normal GFR (23) with a p value of 0.001. Hb was lower (12.5vs 13.9 p<0.01) and Grace score was higher (45 vs44 p<.001) in patients with impaired GFR vs patients with normal GFR. Percentage of cardiogenic shock and death was respectively higher in renal impairment (12(60%) vs 8 (40%) with p of 0.004); (10(62.5%) vs 6(37.5%) with p 0.005. Conclusion: The magnitude of renal impairment is significant in our study in the most deadly complication: cardiogenic shock and death; which confirms that outcomes of coronary artery disease especially in acute coronary syndrome are significantly poorer in patient with kidney disease.
导言:慢性肾脏病(CKD)本身就是冠状动脉疾病(CAD)发病的一个独特风险因素。值得注意的是,冠状动脉疾病是导致慢性肾脏病患者患病和死亡的主要原因。此外,患有慢性肾脏病的人患上冠状动脉粥样硬化症(CAD)的后果往往更严重。除了传统的风险因素外,与尿毒症相关的许多因素,包括炎症、氧化应激、内皮功能障碍、冠状动脉钙化、同型半胱氨酸水平升高以及使用免疫抑制剂,都与动脉粥样硬化加速的风险增加有关。目的和方法:在本研究中,我们旨在评估肾功能损害对急性冠状动脉综合征患者的不同影响。我们在拉巴特军事教学医院心脏科重症监护室进行了这项研究。研究结果本研究共纳入 318 名患者。平均年龄为 63.8 +/- 9.41 岁,77%(244/318)为男性。72.8%(220/318)的患者肾功能正常。在 318 名患者中,121 人(38.3%)为 STEMI,154 人(48.7%)为 NSTEMI,41 人(13%)为不稳定型心绞痛。肾功能正常患者的平均年龄为 61.8 岁,而肾功能受损患者的平均年龄为 68.1 岁,年龄差异显著,P 值小于 0.001。与 GFR 正常的患者(23 例)相比,GFR 受损的患者有更多既往 PCI 病史(21 例),P 值为 0.001。与 GFR 正常的患者相比,GFR 受损的患者血红蛋白较低(12.5 对 13.9,P<0.01),Grace 评分较高(45 对 44,P<0.001)。肾功能受损患者发生心源性休克和死亡的比例分别较高(12(60%)对 8(40%),P<0.004);(10(62.5%)对 6(37.5%),P<0.005)。结论在我们的研究中,肾功能损害对最致命的并发症:心源性休克和死亡的影响很大;这证实了肾脏疾病患者的冠状动脉疾病预后,尤其是急性冠状动脉综合征预后明显较差。
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引用次数: 0
Identifying and Isolating of H. pylori in patients who are experiencing Inflammation in their Gastrointestinal tract 在胃肠道发炎的患者中识别和分离幽门螺杆菌
Pub Date : 2024-01-09 DOI: 10.47191/rajar/v10i1.02
Dhuha Abdullah Kadhim, Hind AL-Hammami
Background: Peptic ulcer illness, stomach cancer and chronic gastritis are gastro-duodenal diseases that are mostly caused by Helicobacter pylori, or H. pylori. Objective: To find out how common Helicobacter pylori infection is among patients at Al Sadder Teaching Hospital in Al-Najaf, Iraq, as well as related factors including age, gender, residency, and blood group. Methods: The entirety of 197 patients—79 men and 118 women—of both genders and various age groups—from under 10 to around 60 years old—were reported to have symptoms of gastrointestinal inflammation. Result: The total numbers of participants in the current study were 197 patients, found 156 (79.2%) positive and 41(20.8%) negative results. Females had a greatest percentage of H. pylori (47.2%), while males had the lowest incidence of prevalence (32%). The age group (31-40) had greatest percentage with (14.7%), followed by the age group (41-50) with (13.2%), and then the age group (21-30) with (11.7%) while lowest percentages in age groups < 10 and ˃ 60 years old. The blood group type O, which had the greatest positive rate (27.9%), was followed by the blood groups types A, B, and AB, with 16.8%, 13.7%, and 4.1%, respectively. People who live in rural areas (30.4%) have a elevated frequency of H. pylori infection when compared with persons who reside in urban areas (28.4%). Conclusion: The findings showed that H. pylori was more frequent in women than men, in rural areas, and in patients between the ages of 31 and 40. Additionally, individuals with the O blood group had higher H. pylori frequency.
背景:消化性溃疡病、胃癌和慢性胃炎是胃十二指肠疾病,主要由幽门螺杆菌(Helicobacter pylori)引起。研究目的了解伊拉克纳杰夫 Al Sadder 教学医院患者中幽门螺杆菌感染的常见程度以及相关因素,包括年龄、性别、居住地和血型。研究方法对 197 名患者(79 名男性和 118 名女性,男女不限,年龄从 10 岁以下到 60 岁左右不等,均有胃肠道炎症症状)进行调查。研究结果参加本次研究的总人数为 197 人,其中 156 人(79.2%)呈阳性,41 人(20.8%)呈阴性。女性幽门螺杆菌感染率最高(47.2%),男性最低(32%)。年龄组(31-40 岁)的幽门螺杆菌感染率最高(14.7%),其次是年龄组(41-50 岁)(13.2%),然后是年龄组(21-30 岁)(11.7%),而年龄组小于 10 岁和˃ 60 岁的幽门螺杆菌感染率最低。O 型血的阳性率最高(27.9%),其次是 A、B 和 AB 型血,分别为 16.8%、13.7% 和 4.1%。与城市居民(28.4%)相比,农村居民(30.4%)感染幽门螺杆菌的频率更高。结论研究结果表明,幽门螺杆菌在女性、农村地区和 31 至 40 岁的患者中的感染率高于男性。此外,O 型血的人幽门螺杆菌感染率更高。
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引用次数: 0
Dissemination and Molecular Characterization of 16s Rna Methylase and Aminoglycoside Modifying Enzymes- Producing P. Aeruginosa Isolated from Burn Specimens in Najaf City 从纳杰夫市烧伤标本中分离出的产 16s Rna 甲基化酶和氨基糖苷修饰酶的绿脓杆菌的传播和分子特征描述
Pub Date : 2024-01-03 DOI: 10.47191/rajar/v10i1.01
Alaa Hamza Jaber Al-Jelehawy, Ammar Kareem Kadhim Al-Furaiji
Background: Pseudomonas aeruginosa is a significant species of bacteria connected with nosocomial infections involving, pneumonia, infections of urinary tract, and damage of the surgical site. Aim of the Study: The aim of this thesis is to investigate the occurrence of genes encoding clinically important 16S rRNA methylases and AMEs enzymes in aminoglycosides resistance P.aeruginosa isolates recovered from Najaf hospitals and the characteristics of these isolates. Methods: a total of 68 specimens were isolated from patients at burn center in Najaf City from the whole study period. The 24 isolates were screened for the sensitivity versus 3 various antibiotics disks of the one class by using Kirby-Bauer disk diffusion method. Results: The resistance rate of 24 isolates of XDR Pseudomonas aeruginosa against aminoglycoside groups: gentamicin, amikacin, and tobramycin were 91.6 %, 83.3 %, and 66.6 %, respectively. However, the resistance profiles of the isolates show that 22 (91.6 %) were resistant to 1 or more antibiotics of aminoglycoside. Present study show that only 3 (12.5%) of XDR isolates harbored ant(4')-IIb gene isolates and none of the XDR isolates investigated were positive for rmtA and aac(6')-IIb gene. Conclusions: This survey has showed for the initial time three isolates harbors the ant(4')-IIb aminoglycoside resistance genes in Iraq.
背景:铜绿假单胞菌是一种与医院内感染有关的重要细菌,包括肺炎、尿路感染和手术部位损伤。研究目的本论文旨在研究从纳杰夫医院分离的耐氨基糖苷类药物的铜绿假单胞菌中编码临床上重要的 16S rRNA 甲基化酶和 AMEs 酶的基因的发生情况以及这些分离物的特征。方法:在整个研究期间,从纳杰夫市烧伤中心的患者身上共分离出 68 份标本。采用柯比-鲍尔盘扩散法对 24 个分离株进行了筛选,以确定其对 3 种同类抗生素盘的敏感性。结果:24 株分离的 XDR 铜绿假单胞菌对氨基糖苷类药物庆大霉素、阿米卡星和妥布霉素的耐药率分别为 91.6%、83.3% 和 66.6%。然而,分离菌株的耐药性特征显示,有 22 个菌株(91.6%)对一种或多种氨基糖苷类抗生素具有耐药性。本研究显示,仅有 3 个(12.5%)XDR 分离物携带 ant(4')-IIb 基因分离物,且所调查的 XDR 分离物中没有一个对 rmtA 和 aac(6')-IIb 基因呈阳性。结论:本次调查首次发现伊拉克有三个分离株携带ant(4')-IIb氨基糖苷类药物耐药基因。
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引用次数: 1
The Contribution of Cattle Fattening to the Improvement of the Living Conditions of Households in the Village of Konna (Mopti) 育肥牛对改善孔纳村(莫普提)家庭生活条件的贡献
Pub Date : 2023-12-16 DOI: 10.47191/rajar/v9i12.03
Dr. Amadou Dia, Dr. Tahirou Tangara, Dr. Fousseny Diallo
The purpose of this study is to analyse the impact of the practice of cattle fattening on the live conditions of the populations in the village of Konna (Mopti). One hundred and thirty one (131) cattle fatteners were interviewed based on a questionnaire focusing mainly on the conduct of the fattening activity; the constraints encountered and the impact of the fattening activity on the living conditions of the respondents, including observations in the field. A descriptive analysis is made with the analysis software SPSS-18 has shown that 95 (72.5%) men against 26 (27.5%) women practice cattle fattening activity. Respondents encounter some difficulties; only 16% benefited from loans from financial institutions. Cattle rationing is mixed, the most used feeds being brown cake (90.8%) and rice bran (85.5%). The acquisition of veterinary products is done on the local market (83.2%), itinerant merchants (6.9%) and ordered from outside (9.9%). The aim of the cattle fattening activity is to increase the pecuniary income for a better living condition. We witness that out of the 131 respondents 31, 3% were able to cover their medical expenses; 26.7% were able to pay for school supplies for their children; 10.7% were able to pay their rent; 67.2% saw an improvement in their food; 24.4% were able to carry out other income generating activities; 15.3% had access to drinking water; 13.7% had access to electricity, and about 23.7% of respondents sleep under an impregnated mosquito net.
本研究的目的是分析育肥牛的做法对孔纳村(莫普提)居民生活条件的影响。根据调查问卷对 131 名育肥牛饲养者进行了访谈,主要侧重于育肥活动的开展情况、遇到的制约因素以及育肥活动对受访者生活条件的影响,包括实地观察。利用分析软件 SPSS-18 进行的描述性分析表明,95 名男性(72.5%)和 26 名女性(27.5%)从事育肥活动。受访者遇到了一些困难;只有 16%的人从金融机构贷款中受益。牛的定量配给参差不齐,最常用的饲料是褐饼(90.8%)和米糠(85.5%)。兽医产品的购买渠道包括当地市场(83.2%)、流动商贩(6.9%)和从外部订购(9.9%)。育肥牛活动的目的是增加经济收入,改善生活条件。我们看到,在 131 名受访者中,31.3% 的人能够支付医疗费用;26.7% 的人能够支付子女的学习用品费用;10.7% 的人能够支付房租;67.2% 的人的伙食有所改善;24.4% 的人能够从事其他创收活动;15.3% 的人能够获得饮用水;13.7% 的人能够用上电,约 23.7%的受访者睡在浸过水的蚊帐里。
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引用次数: 0
Innovation in Research-Oriented Teacher Training in Universities of Education in Vietnam 越南教育大学以研究为导向的教师培训创新
Pub Date : 2023-12-15 DOI: 10.47191/rajar/v9i12.02
Assoc. Prof. Dr. Truong Thi Bich
The context of globalization and international integration sets forth new requirements on the quality of human resources, thereby demanding improvement of the quality of teacher training in universities of education. International studies shows that scientific research-based teacher training is proving to be an effective method. The importance of scientific research in teacher training is mentioned in the article, also specific research-oriented teacher training methods are pointed out and analyzed: teacher training with problem based situations, teacher training using practical action research.
全球化和国际一体化的背景对人力资源的质量提出了新的要求,从而要求提高教育大学师资培训的质量。国际研究表明,以科学研究为基础的教师培训被证明是一种有效的方法。文章提到了科学研究在教师培训中的重要性,还指出并分析了具体的研究型教师培训方法:基于问题情境的教师培训、利用实际行动研究的教师培训。
{"title":"Innovation in Research-Oriented Teacher Training in Universities of Education in Vietnam","authors":"Assoc. Prof. Dr. Truong Thi Bich","doi":"10.47191/rajar/v9i12.02","DOIUrl":"https://doi.org/10.47191/rajar/v9i12.02","url":null,"abstract":"The context of globalization and international integration sets forth new requirements on the quality of human resources, thereby demanding improvement of the quality of teacher training in universities of education. International studies shows that scientific research-based teacher training is proving to be an effective method. The importance of scientific research in teacher training is mentioned in the article, also specific research-oriented teacher training methods are pointed out and analyzed: teacher training with problem based situations, teacher training using practical action research.","PeriodicalId":20848,"journal":{"name":"RA JOURNAL OF APPLIED RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139178369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the Present State of Communication Skills Education via Play for Fifth Grade Pupils in Hanoi City, Vietnam 调查越南河内市五年级学生通过游戏进行交流技能教育的现状
Pub Date : 2023-11-30 DOI: 10.47191/rajar/v9i11.05
Tran Thi Lan
The significance of effective communication skills in the contemporary society cannot be overstated. Consequently, educational institutions in Vietnam consistently emphasize the cultivation of communication skills among students through a plethora of dynamic and engaging activities, encompassing both scholastic and recreational pursuits. This paper delves into the existing landscape, offering an evaluation of the accomplished strides, while also addressing the persisting constraints within the domain of communication skills education via playful methodologies, specifically focusing on primary schools within select districts of Hanoi city. These observations pave the way for forthcoming research endeavors aimed at surmounting these limitations and further amplifying the strengths inherent in furnishing students with adept communication skills.
在当代社会,有效沟通技能的重要性怎么强调都不为过。因此,越南的教育机构一直强调通过大量充满活力、引人入胜的活动来培养学生的沟通技能,这些活动既包括学术活动,也包括娱乐活动。本文以河内市部分地区的小学为研究对象,深入探讨了现有的情况,对已取得的进步进行了评估,同时还通过游戏方法解决了沟通技能教育领域长期存在的制约因素。这些观察结果为即将开展的研究工作铺平了道路,这些研究工作旨在克服这些局限性,进一步发挥培养学生熟练交流技能的内在优势。
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引用次数: 0
The Aquatic Environment and Pharmaceutical Products- A Review 水生环境与医药产品--综述
Pub Date : 2023-11-18 DOI: 10.47191/rajar/v9i11.03
Chichirez N. Cristina-Mihaela
In recent decades, more and more pharmaceutical products exist in the nature. In many parts of the Globe, and especially close to urban areas, medicines have been presented in surface waters, groundwaters and soils. This is related to the growth in the utilisation of medicine and the development of analytical detection techniques in order determination of these traces of compounds in the environment. Pharmaceuticals reach the nature through the discharge of effluents from urban waste water treatment plants, the discharge of effluents from hospitals and drug factories, the using of sewage sludge in agriculture, the breeding of herbivorous animals, the treatment of pets, the spreading of manure and aquaculture, the improper disposal in landfills of unused pharmaceutical substances and contaminated waste. Researches showed that pharmaceutical products and residues are mainly present in water bodies and that they are partly eliminated by conventional wastewater treatment plants, which currently cannot effectively filter all pharmaceuticals.
近几十年来,大自然中存在越来越多的药品。在全球许多地方,尤其是靠近城市的地区,地表水、地下水和土壤中都出现了药物。这与药品使用量的增长以及分析检测技术的发展有关,以便确定环境中的这些痕量化合物。药物通过城市污水处理厂的污水排放、医院和制药厂的污水排放、农业污水污泥的使用、食草动物的饲养、宠物的治疗、粪便的散播和水产养殖、未使用药物和受污染废物的不当填埋处理等途径进入大自然。研究表明,医药产品和残留物主要存在于水体中,传统的污水处理厂可以部分消除这些物质,但目前还不能有效地过滤所有的药物。
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引用次数: 0
Interrelations between Perceptive-Cognitive Factors and Behavioural Variables to Level Diagnosis of People with Autism Spectrum Disorder 感知认知因素与行为变量之间的相互关系对自闭症谱系障碍患者的诊断水平的影响
Pub Date : 2023-11-10 DOI: 10.47191/rajar/v9i11.02
M. Rúa
Relationships analysis between perceptual-cognitive factors and behavioural variables it makes up autism spectrum disorder (ASD) differential specific diagnosis, constitute a fundamental recurrent of currently research, then found data allow the construction of integrated evaluation scales to validate more complete and reliable diagnosis of people with ASD. The interdimensional diagnostic Scale has been applied and coded for 10 dimensions: 1) conceptual units, 2) signifiers, 3) hierarchy, 4) nodal relationships, 5) categorical relationships, 6) Recovery, 7) social interaction, 8) social communication, 9) stereotypical behaviours, and 10) restrictive behaviours. A total of 75 participants with ASD have participated in this study of three ASD´ intensity levels and different age intervals, from 3 years old. Data analyses focused along study the factorial analysis determinant (KMO and Bartlett's test) statistic, as well as, bivariate correlations analysis for three dimensions calculated statistically: "processing", "social" and "behaviours", show significant critical inter-relational levels (sig: .00), which allows conclude to existence of highly relationships between both variables group and their practical applications for consequent, reliable and valid diagnosis process. Finally, the statistical data of your application to perform the level diagnostic analysis is completed, through corresponding statistical percentage, means and standard deviations, to facilitate the ASD level 1-2-3 diagnostic way.
感知-认知因素与行为变量之间的关系分析构成了自闭症谱系障碍(ASD)的差异化具体诊断,是当前研究的一项基本的经常性工作。跨维度诊断量表已应用于 10 个维度并进行了编码:1)概念单位;2)标志物;3)层次结构;4)节点关系;5)分类关系;6)恢复;7)社会交往;8)社会交流;9)刻板行为;10)限制行为。共有 75 名患有自闭症的参与者参加了这项研究,他们的自闭症强度分为三个等级,年龄也从 3 岁开始不同。数据分析的重点是研究因子分析决定因素(KMO 和 Bartlett 检验)统计,以及统计计算出的三个维度的双变量相关分析:"处理"、"社会 "和 "行为 "这三个维度显示出显著的临界相互关系水平(sig:.00),从而得出这两个变量组之间存在高度关系的结论,并将其实际应用于相应的、可靠和有效的诊断过程。最后,通过相应的统计百分比、平均值和标准偏差,完成了对您的应用程序进行水平诊断分析的统计数据,以促进 ASD 1-2-3 水平诊断方法。
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引用次数: 0
Challenges Affecting Effective Application of Strategic Management Techniques in the Process of Implementing Organisational Changes in Zambia Correctional Service 在赞比亚惩教服务实施组织变革过程中影响战略管理技术有效应用的挑战
Pub Date : 2023-10-26 DOI: 10.47191/rajar/v9i10.06
Maureen Himbondo
Strategic management is a management tool that both public and private sector entities adopt to improve organizational performance especially in the process of implementing organizational changes. Zambia Correctional Service in particular has been undergoing a paradigm shift in order to implement new security sector reforms. Like many other public entities world over has continuously recorded failure in achieving strategic objectives, as noted by cabinet Office’s 2020 performance assessment. Therefore, this study sought to identify challenges that affect effective application of strategic management techniques in the process of implementing organisational changes. This research is a literature review that gathered facts from literature findings of a scientific publications and existing data in the study area of the topic under review. Research findings indicate that the Service has been experiencing a number of challenges and these include; having an ambiguous vision statement, operating on an outdated organisational structure, inadequate end-user engagement and ineffective examination and modification of work processes. The findings show that the Service needs to develop a model for application of strategic management techniques that will support implementation of organisational changes. The model should include element such as establishing a clear end goal (vision), revise the structure to suit the demands of the current strategic plan, conduct program impact assessments to effectively measure performance and examine and modify work processes for effective and efficient public resource management.
战略管理是公共和私营部门实体采用的一种管理工具,以提高组织绩效,特别是在实施组织变革的过程中。特别是赞比亚惩教署,一直在进行模式转变,以便执行新的安全部门改革。正如内阁府2020年绩效评估所指出的那样,与世界上许多其他公共实体一样,它在实现战略目标方面不断失败。因此,本研究试图确定在实施组织变革的过程中影响战略管理技术有效应用的挑战。本研究是一项文献综述,从科学出版物的文献发现和研究领域的现有数据中收集事实。研究结果表明,事务处经历了一些挑战,其中包括;有一个模糊的愿景陈述,在一个过时的组织结构上运作,最终用户参与不足,工作流程的检查和修改无效。调查结果表明,该处需要发展一种应用战略管理技术的模式,以支持实施组织变革。该模式应包括诸如建立明确的最终目标(远景)、修改结构以适应当前战略计划的要求、进行方案影响评估以有效地衡量绩效、审查和修改工作程序以实现有效和高效率的公共资源管理等因素。
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引用次数: 0
Fitz-Hugh-Curtis Syndrome: A Case Report Emphasizing Timely Recognition and Management in Pelvic Inflammatory Disease 菲兹-休-柯蒂斯综合征:一例强调盆腔炎及时识别和治疗的报告
Pub Date : 2023-10-20 DOI: 10.47191/rajar/v9i10.05
Talal Mohammed AlShahri, Kamal Mohammad AlDammad, Dema Wahid Hammami, Mohamed Sofian Abdelkefi, Sarah Saud Alharbi, Abrar Elnazeer Said
Fitz-Hugh-Curtis syndrome (FHCS) is a rare complication of pelvic inflammatory disease (PID), that presents with right upper quadrant abdominal pain, often mimicking hepatic, or biliary conditions. Timely diagnosis is crucial to prevent complications. This case report represents 34 years old female came to ER complaining from right upper quadrant abdominal pain and nausea for one month.
菲兹-休斯-柯蒂斯综合征(FHCS)是盆腔炎(PID)的一种罕见并发症,表现为右上腹部疼痛,通常模仿肝脏或胆道疾病。及时诊断对预防并发症至关重要。本病例报告描述一名34岁女性因右上腹腹痛及恶心一个月来急诊室就诊。
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引用次数: 0
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RA JOURNAL OF APPLIED RESEARCH
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