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039 Clinical pathway for pain management in a pain day care unit: use of intravenous lidocaine for neuropathic pain 039疼痛日间护理病房疼痛管理的临床路径:静脉注射利多卡因治疗神经性疼痛
Pub Date : 2010-04-01 DOI: 10.1136/QSHC.2010.041624.91
Piano Virginie, Rabary Olivier, L. Michel
Background and objectives In pain management clinics, refractory chronic pain often needs to be managed by potentially iatrogenic treatments that have not been fully validated in terms of evidence-based medicine, such as intravenous lidocaïne treatment for neuropathic pain (NP). Our primary objective was to evaluate professional practices in the pain day care unit of Nice university hospital. Secondary objectives were to study the efficacy and safety of intravenous lidocaine treatment of NP and to assess the heath economics impact of our quality improvement programme. Programme Our quality improvement programme was part of a wider initiative to harmonise clinical practices in pain clinics in France. It took place between November 2007 and September 2009 and was implemented by three physicians. It followed the Plan-Do-Check-Act procedure. ‘Plan’: The first step was (i) a systematic literature review on the use of intravenous lidocaine to treat NP, (ii) consultation of the HAS practice appraisal process and of the 2010 version of the HAS accreditation manual for healthcare organisations, and (iii) consultation of the rules and regulations on day hospitals. After an analysis of quality improvement methods used in day hospitals, we selected the clinical pathway method. ‘Do’. A multidisciplinary team meeting (MTM) on pain was held every week in order to validate the indications for intravenous lidocaine and monitor progress. The following documents were drawn up: a care protocol, procedures to be followed in the case of adverse events, a patient information and consent form, a prescription and evaluation form, a standard letter requesting an evaluation by a cardiologist, MTM and hospital reports for the GP, a phone follow-up form. A vital signs monitor was purchased and emergency trolley equipment was brought up to standard. ‘Check and act’. Three audit rounds were carried out using a 10-item questionnaire. Data on efficacy (pain intensity on a visual analogue scale (VAS), patient satisfaction), safety (‘active’ recording of side effects), and health economics were collected. Results The quality improvement programme was integrated by the pain team into their daily practice. Between the first and last round of the audit, compliance with quality criteria increased markedly from 45%–95% to 80%–100%, according to item. Overall, 53% (63/119) of patients experienced a 30% reduction in pain intensity (VAS) and 29.4% (35/119) reported that they were satisfied or very satisfied with the treatment. Adverse events occurred in 46% of patients (55/119). There were four early treatment interruptions but no serious adverse events. After an initial 36% reduction in 2008, the recruitment level at the end of the programme was identical to that before programme implementation. A clear increase in activity-based funding was observed at the end of the programme (+66%). Discussion Our programme led to an improvement in practice. This justified the resources allocated wit
背景和目的在疼痛管理诊所,难治性慢性疼痛通常需要通过潜在的医源性治疗来管理,这些治疗在循证医学方面尚未得到充分验证,例如静脉注射lidocaïne治疗神经性疼痛(NP)。我们的主要目的是评估尼斯大学医院疼痛日间护理部门的专业实践。次要目的是研究静脉注射利多卡因治疗NP的有效性和安全性,并评估我们的质量改进方案对健康经济学的影响。我们的质量改进计划是协调法国疼痛诊所临床实践的更广泛倡议的一部分。试验于2007年11月至2009年9月期间进行,由三名医生实施。它遵循计划-执行-检查-行动程序。“计划”:第一步是(i)对静脉注射利多卡因治疗NP的使用进行系统的文献综述,(ii)咨询医疗机构的HAS实践评估过程和2010版HAS认证手册,以及(iii)咨询日间医院的规章制度。通过对日间医院质量改进方法的分析,我们选择了临床路径法。“做”。每周召开一次多学科疼痛小组会议(MTM),以验证静脉注射利多卡因的适应症并监测进展。起草了以下文件:护理协议、发生不良事件时应遵循的程序、患者信息和同意书、处方和评估表、要求心脏病专家进行评估的标准信函、MTM和全科医生的医院报告、电话随访表。购置了生命体征监测仪,并使应急推车设备达标。“检查并行动”。采用10项问卷进行了三轮审计。收集了疗效(视觉模拟量表(VAS)疼痛强度、患者满意度)、安全性(副作用的“主动”记录)和卫生经济学方面的数据。结果疼痛组将质量改进方案纳入日常实践。根据项目,在第一轮和最后一轮审计之间,质量标准的符合性从45%-95%显著增加到80%-100%。总体而言,53%(63/119)的患者疼痛强度(VAS)降低了30%,29.4%(35/119)的患者对治疗感到满意或非常满意。46%的患者发生了不良事件(55/119)。有四次早期治疗中断,但没有严重的不良事件。在2008年最初减少36%之后,项目结束时的招聘水平与项目实施前相同。在方案结束时观察到基于活动的供资明显增加(+66%)。我们的课程在实践上有了改进。这证明了日间医院分配给静脉注射利多卡因治疗神经性疼痛的资源是合理的。治疗效果与文献记录相似。然而,我们没有遇到严重的不良事件。我们良好的安全性可能是由于心脏病专家在开始治疗前的系统评估和日间医院的积极监测。在为难治性慢性疼痛建立“疾病相关组”后,基于活动的成本计算节省了资金,但日间医院更好的入住率也弥补了最初活动减少的损失。总之,临床路径是一种简单有效的方法,可以优化疼痛临床实践,限制难治性慢性疼痛治疗相关的医源性风险。研究背景:双胞质结构、双胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构、单胞质结构。目的:将<s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> (dj)和<s:1> <s:1> <s:1> <s:1> (HDJ)与<s:1> <s:1> <s:1> (dj)和<s:1> <s:1> (dj)与<s:1> <s:1> (dj)与<s:1> (EPP)与<s:1> (EPP)与<s:1> (EPP)与<s:1> (EPP)与<s:1> (EPP)与<s:1> (EPP)与<s:1> (EPP)与<s:1> (EPP)与<s:1> (EPP)与<s:1> (DQ)与(DQ)与(DQ)相结合。两个目标分别是:第2个目标是:<s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1>··························项目计划- Il年代'agissait一revue bibliographique创造苏尔:我)la丽芙·visee antalgique倒les DN, ii) la methodologie de la DQ de la已经用曼努埃尔•德认证v2010 iii) la circulaire组织encadrant les活动HDJ, associee一个分析程序在课程en HDJ par一个反射d 'equipe有的勒选择du chemin倩碧像outil d 'amelioration。 “do”- DQ于2007年11月至2009年9月进行,由3名医生管理。这导致了每周一次的多学科协调会议,以验证和评估Liv的建议。与此同时,还创建了管理协议等文件。它需要购买一个饱和计,并使应急小车符合要求。它为创建一个包含10个相关标准的审计网格提供了理由,以评估实践的质量。“检查和行动”——在此过程中进行了三次连续的质量审核。同时评估疗效标准:视觉模拟疼痛评估(vas)和患者满意度(icmp)。建立了主动不良反应(EI)收集程序,PMSI检索了医学经济学数据。结果DQ已很好地融入日常实践。在审核1和审核3之间,质量标准通过40%-95%到80-100%项目符合性。55%(63/119)的患者vas降低了30%,29.4%(35/119)的患者感觉很好或非常好。46%(55/119)有ia,其中4例需要停止输液,但没有严重的ia。在活动队列最初减少(-36%)后,2009年恢复了2007年参考年的数字。同期第二季度的估值明显增加(+66%)。qfd在实践中产生了定性的改进。Liv对DN的疗效与文献数据相当。相比之下,由于在系统的心脏病会诊中预先选择了患者,我们没有观察到严重的ei。最初的活动减少与遵守边境通知规定的更严格的治疗标准有关。经济上的收益可以解释为jhd会议的重新评估,创造了一种特定的GHM“不可减少的慢性疼痛”,但也可以解释为由于jhd占用率的提高而导致的最初活动减少的补偿。该方案已在PACA区域疼痛结构实践协调框架内得到验证。该fd允许tdt - mp医生的epp验证。它通知了认证手册v 2010的标准12a E2第4章。结论CC的DQ在三级疼痛管理结构中优化了jhd潜在的医源性治疗。由一个试点护理小组领导,它允许围绕卓越的目标团结一个团队。
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引用次数: 0
284 Implementation of a multidimensional program to improve medical prescription in the elderly within a university hospital nephrology unit 284 .在大学医院肾病科实施一项多维方案,以改善老年人的医疗处方
Pub Date : 2010-04-01 DOI: 10.1136/QSHC.2010.041632.40
C Tourette-Turgis, C. Bagnis, M. Rébillon, L. Pereira-Paulo
Objectives and Context Chronic kidney disease (CKD) patients over 65 mostly suffer from two or more comorbidities (75% have hypertension, 35% have diabetes) with a mean of 4.5 chronic conditions. Prescriptions delivered by the Nephrology unit of a University Hospital in a urban area show an average number of medications from 6 to 15 different drugs for the treatment of both acute events and several chronic diseases. Patients seem to hierarchise their intake of medications according to the negative impact of symptoms on their quality of life, (such as pain, discomfort) and tend to omit taking medications that are active on silent symptoms although these symptoms if not addressed may be life threatening. Moreover, the design of most drugs (pills, or inaccurately labelled containers, leaflets) is not appropriate for the elderly especially for those suffering from disabling comorbidities (sight defect, cognitive disorder or troubles with fine grasping in the case of arthritis). The burden of the number of medication prescribed and the complexity of changes expected from the patients to appropriately cope with the prescribed regimen is particularly heavy to elderly patients. In other words, CKD seniors cannot develop their own self-care skills and therefore experience frequent unintentional adherence or relapse/complications in their care caused by external conditions. These obstacles have a serious negative impact on their health maintenance and outcomes. Therefore, educational programs for the elderly with CKD must focus on strategies to avoid or prevent non intentional non adherence. Methods A multidisciplinary integrated educational program was implemented in 2007 in the Nephrology department with: analysis of patients' needs through a survey (interviews of 21 patients) analysis of the subjective experience of dialysis sessions in 14 patients and 15 nurses working in the dialysis unit design of a survey exploring patients' educational needs outpatient consultation delivered by trained nurses on adherence available 6 days a month weekly educational and patient workshop including the results of the survey focused on patients' needs creation of educational material on more than 20 different medications (information leaflet for patients) «medication info» consultation for every patient checking out from the nephrology unit intensive communication and training program on «education in chronic disease) towards health care providers in the renal unit design of educational tools for the team performing educational sessions: poster with life-size pictures of pills for 61 of the most frequently prescribed drugs, therapeutic planning, risk reduction pyramid for drug's use, scripts for interviewing patients (to work on adherence)… Results Improvement of care coordination Use of a negotiated prescription process» after having worked individually together with the patient on the aims of the therapeutic projects and having defined common goals for the patient an
患者似乎根据症状对其生活质量(如疼痛、致残症状)的负面影响来优先考虑治疗,而不是对发病率高的无形症状的治疗。此外,galenics和药品包装不适合有精细理解障碍甚至认知障碍的患者。这一群体在行使自我照顾能力方面遇到了困难。对老年人进行干预的首要目标之一是防止有意的、决策的或情境性的遵守中断,这在死亡或严重并发症中起着先天的作用。自2007年以来,肾脏科部署了多层面和多学科的干预措施:实行每月6天的个性化护理会诊,讲习班的主题的周刊的调查结果向21名患者需要提供药品中创建表为内容服务的医护和真人大小的一个病人在摄影方面的61名不同处方药品在该处透析病人进行了交叉调查15和14名护工在血液透析股执行一个关于教育需求的问卷药物咨询服务的21名患者在出院时实施了密集的沟通政策,并由护士进行同行教育,服务的医生实现了教育工具,如“我的药物是干什么用的?”治疗计划,降低药物风险的金字塔,遵守面试指南共情来处理这些困难与患者及其亲属的临床结果改善协调和协调发展保健药物处方的模型与护士与病人和重新谈判建立起银行的医学病例档案MOTHIV医务辅助人员参与模式的处方、医疗决策模型特别是在某些情况下在透析单元(例如:停产决定陪伴患者透析)提高病人的满意度表现为他们正常上学,工作室的发言有助于对其药品临床实践执行指标的讨论,包括防止iatrogénie保健专业人员编写的(与HAS, 2010年出版)将补充这些定性结果,关于疗效(充分治疗)、护理安全性(医源性预防)和患者参与(依从性和治疗教育)的客观措施。这些指标将构成基准数字,作为护理质量的杠杆和保证。结论改进药物处方家里老人是一个多维度的过程,需要更改布局精心组织、集体技能的习得,尤其是加强人际关系技能留给球队朝着人口累积的躯体功能、情感和社会脆弱性。医疗团队、患者及其家属之间共享的基准数字将有助于加强和加强所采取的措施。
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引用次数: 0
072 Clinical impact of quality improvement actions decided in morbidity-mortality reviews (MMR) in intensive care units 072重症监护病房发病率-死亡率评价(MMR)中质量改进措施的临床影响
Pub Date : 2010-04-01 DOI: 10.1136/qshc.2010.041616.3
C. Philippe, Moret Leila, Naux Edouard, Vanier Antoine, Demeure Dit Latte Dominique, Asehnoune Karim
Background and objectives The development of morbidity-mortality reviews (MMR) in high-risk units is one of the main objectives of the quality improvement policy of Nantes university hospital. Currently, 25 units are engaged in the analysis of clinical adverse events. Our surgical intensive care unit (ICU) was a forerunner in implementing this policy. Programme The ICU has 14 beds and an average intake of 700 patients per year. MMRs have been taking place every 2 months since January 2007. MMR participants are the medical staff of the unit, any on duty physicians, nursing staff and other allied healthcare professionals, and external experts whenever required. A charter establishing rules has been drawn up. The following adverse events are collected in a restricted access database: deaths, unplanned extubations, events related to medical devices, falls, near-misses, unplanned readmissions, and problems with handover communication. The person responsible for the database reviews all data entered and selects the files requiring in-depth analysis (2 to 5 files per meeting). A report with suggested improvement actions is handed to all concerned at the end of the meeting. A process indicator for each type of adverse event is applied once a year to measure the impact of the actions undertaken. Results and clinical impact From January 2007 to December 2008, 1411 patients were hospitalised in our ICU (693 in 2007, 718 in 2008). A total of 199 adverse events were entered into the database, 70 files were reviewed (MMR), and 25 improvement actions were undertaken. A statistically significant impact was observed for 3 types of improvement action: (i) increasing staff awareness of agitation in patients, (ii) updating protocols for sedation and physical restraint, (iii) purchasing better suited medical supplies. We noted a 46% decrease in the number of unplanned extubations (they fell from 20 (0.59/100 days of ventilation) to 11 (0.32/100 days of ventilation), p<0.01), a 85% decrease in the number of snatched medical devices (from 20 to 3, p<0.001), and the disappearance of accidental falls from the bed or chair (from 3 to 0). Such events are common in surgical ICUs which frequently admit patients with head trauma or patients intoxicated by alcohol or drugs. Discussion and conclusion A quality improvement programme that has a positive clinical impact promotes staff motivation. Interest in measuring the quality of health care is increasing among health care professionals. We are now including further variables in our database in order to optimise nurse planning (eg, patient-to-nurse ratio, where the nurse was when the adverse event occurred). Further developments should include promoting nursing staff participation through education and the choice of a time slot for the meetings compatible with high attendance. High attendance can help alleviate fears of judgemental attitudes. MMRs have also encouraged staff interest in patient safety. Sharing results among team
背景与目的南特大学医院质量改进政策的主要目标之一是在高危病房开展发病率-死亡率评价(MMR)。目前,有25个单位从事临床不良事件的分析。我们的外科重症监护室(ICU)是实施这一政策的先行者。重症监护室有14张病床,平均每年接收700名病人。mmr自2007年1月以来每两个月进行一次。MMR参与者是单位的医务人员、任何值班医生、护理人员和其他专职保健专业人员,以及必要时的外部专家。制定规则的章程已经起草。以下不良事件收集在限制访问数据库中:死亡、计划外拔管、与医疗器械有关的事件、跌倒、未遂、计划外再入院以及交接沟通问题。数据库负责人审查所有输入的数据,并选择需要深入分析的文件(每次会议2到5个文件)。会议结束时,向所有相关人员提交一份载有改进措施建议的报告。每一种不良事件的过程指标每年应用一次,以衡量所采取行动的影响。结果及临床影响2007年1月至2008年12月,我院ICU共收治1411例患者(2007年693例,2008年718例)。共有199个不良事件被录入数据库,70个文件被审查(MMR),并采取了25个改善措施。观察到三种改善行动产生了统计上显著的影响:(一)提高工作人员对患者躁动的认识;(二)更新镇静和身体约束的规程;(三)购买更合适的医疗用品。我们注意到计划外拔管次数减少了46%(从20次(0.59/100天通气)减少到11次(0.32/100天通气),p<0.01),抢走医疗器械的次数减少了85%(从20次减少到3次,p<0.001),意外从床上或椅子上摔下来的情况消失了(从3次减少到0次)。这些事件在外科icu中很常见,这些icu经常收治头部创伤患者或酒精或药物中毒患者。具有积极临床影响的质量改进方案可提高员工的积极性。卫生保健专业人员对衡量卫生保健质量的兴趣正在增加。我们现在在我们的数据库中加入了更多的变量,以优化护士计划(例如,患者与护士的比例,当不良事件发生时护士在哪里)。进一步的发展应包括通过教育促进护理人员的参与,并为会议选择一个与高出席率相适应的时间段。高出勤率有助于减轻人们对评判态度的恐惧。mmr还鼓励了工作人员对患者安全的兴趣。在团队之间分享结果似乎是促进质量改进计划的一种方式。Contexte盟楚de南特le开发署des时俗讽刺de Morbi-Mortalite (RMM)在secteurs有伤风化的est两个des轴内de la政治人民军。1 .《关于交换交换和交换交换的报告》,《关于交换交换和交换交换的报告》,《关于交换交换和交换交换的报告》,《关于交换交换和交换交换的报告》,《关于交换交换和交换交换的报告》,2007年。“联合方案”包括14个医院和医院,每年有700名病人。2007年1月,RMM组织发布了一份报告。我的参与者们,我的参与者们,我的参与者们,我的参与者们,我的参与者们,我的参与者们,我的参与者们,我的参与者们,我的参与者们,我的参与者们,我的参与者们。一份章程正式规定了这些规则的功能。有一种方法可以将所有的samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、samsamas、通讯问题。负责管理人力资源管理的人员撤销档案,确定和确定所有的人力资源管理人员,并选择所有的人力资源管理人员进行分析。双份:5份,分别是:1份,3份,3份,3份,4份,3份,3份,3份,3份,3份。不完整的统计数据显示,在有关人员的统计数据中,所有的数据都是有关的。非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性、非指示性。在2007 - 2008年期间,有199个<s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1>和/或<s:1> <s:1> <s:1>和/或<s:1> <s:1> <s:1>和/或<s:1> <s:1>和/或<s:1> <s:1>和/或<s:1> <s:1>和/或<s:1> <s:1>和/或<s:1>和/或与医院和医疗有关的<s:1> <s:1>和/或与医疗有关的<s:1>和/或与医疗有关的<s:1>和/或与医疗有关的<s:1>和/或与医疗有关的<s:1>和/或与医疗有关的<s:1>和/或与医疗有关的<s:1>和/或组织的数据(分别为2007年693个和2008年718个)。70份关于在RMM中进行的<s:2>和/或<s:2>和/或分析的档案,以及25项关于<s:2>和/或<s:2>和/或组织的行动。
{"title":"072 Clinical impact of quality improvement actions decided in morbidity-mortality reviews (MMR) in intensive care units","authors":"C. Philippe, Moret Leila, Naux Edouard, Vanier Antoine, Demeure Dit Latte Dominique, Asehnoune Karim","doi":"10.1136/qshc.2010.041616.3","DOIUrl":"https://doi.org/10.1136/qshc.2010.041616.3","url":null,"abstract":"Background and objectives The development of morbidity-mortality reviews (MMR) in high-risk units is one of the main objectives of the quality improvement policy of Nantes university hospital. Currently, 25 units are engaged in the analysis of clinical adverse events. Our surgical intensive care unit (ICU) was a forerunner in implementing this policy. Programme The ICU has 14 beds and an average intake of 700 patients per year. MMRs have been taking place every 2 months since January 2007. MMR participants are the medical staff of the unit, any on duty physicians, nursing staff and other allied healthcare professionals, and external experts whenever required. A charter establishing rules has been drawn up. The following adverse events are collected in a restricted access database: deaths, unplanned extubations, events related to medical devices, falls, near-misses, unplanned readmissions, and problems with handover communication. The person responsible for the database reviews all data entered and selects the files requiring in-depth analysis (2 to 5 files per meeting). A report with suggested improvement actions is handed to all concerned at the end of the meeting. A process indicator for each type of adverse event is applied once a year to measure the impact of the actions undertaken. Results and clinical impact From January 2007 to December 2008, 1411 patients were hospitalised in our ICU (693 in 2007, 718 in 2008). A total of 199 adverse events were entered into the database, 70 files were reviewed (MMR), and 25 improvement actions were undertaken. A statistically significant impact was observed for 3 types of improvement action: (i) increasing staff awareness of agitation in patients, (ii) updating protocols for sedation and physical restraint, (iii) purchasing better suited medical supplies. We noted a 46% decrease in the number of unplanned extubations (they fell from 20 (0.59/100 days of ventilation) to 11 (0.32/100 days of ventilation), p<0.01), a 85% decrease in the number of snatched medical devices (from 20 to 3, p<0.001), and the disappearance of accidental falls from the bed or chair (from 3 to 0). Such events are common in surgical ICUs which frequently admit patients with head trauma or patients intoxicated by alcohol or drugs. Discussion and conclusion A quality improvement programme that has a positive clinical impact promotes staff motivation. Interest in measuring the quality of health care is increasing among health care professionals. We are now including further variables in our database in order to optimise nurse planning (eg, patient-to-nurse ratio, where the nurse was when the adverse event occurred). Further developments should include promoting nursing staff participation through education and the choice of a time slot for the meetings compatible with high attendance. High attendance can help alleviate fears of judgemental attitudes. MMRs have also encouraged staff interest in patient safety. Sharing results among team","PeriodicalId":20849,"journal":{"name":"Quality and Safety in Health Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86688728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
102 Antibiotic Kit for antibioprophylaxis in surgery: promoting the best use of antibiotics in the operating room 102外科抗生素预防用抗生素试剂盒:促进手术室抗生素的最佳使用
Pub Date : 2010-04-01 DOI: 10.1136/QSHC.2010.041624.35
Carles Michel, Bornard Loic, L. Florence, Raucoules Marc
Setting Surgical antibiotic prophylaxis is one of the critical tools to prevent Surgical Site Infections (SSIs) and needs, for its optimisation, to be in accordance with specific guidelines. Antibiotic consumption in the operating room reaches almost 30% of the total hospital antibiotic expenses and thus is a major goal in the way to improve the overall antibiotic use. The implementation of personalised surgical antibiotic prophylaxis kits (SAPKs) has been associated with an improvement of the compliance to the guidelines (82% of consistency).1 Nevertheless, these kits are associated with a additional work load impairing their use in daily practice. The aim of the process presented here is to move from personalised to SAPKs « by type of surgery » in the way to make the implementation of SAPKs easier and sustainable without impairing its efficiency. Program Kits are made at the Hospital Pharmacy (in accordance with the French Society of Anesthesiology (SFAR) Guidelines. They are individual small paper bags including the labelling of the kit and the antibiotic (name and dose, how to use it). The allocation of the all week antibiotics is renewed every Friday by the Hospital Pharmacy (full-empty replacement using a rolling closet located in the recovery room). To assess the impact of this process we designed an exposed-non exposed prospective study (Visceral and Orthopaedic Surgeries) defining two groups: non exposed patients having a freely prescribed surgical antibiotic prophylaxis (fpSAPKs) versus « by type of surgery » (tsSAPKs). Results 420 patients have been included. The two groups are comparable regarding the type of surgery (Orthopaedic 33%, Visceral 66%), the age, gender, ASA and Altemeier classes and duration of surgery. A surgical antibiotic prophylaxis has been prescribed in 88% of cases in the fpSAPKs versus 90% in tsSAPKs (p=ns). The assessment of the main points of antibiotic prophylaxis use showed a significant improvement of the consistency of the reason of the prescription (93% vs 86%, p=0.01) and of the chosen drug (88% vs 81%, p=0.04). The only one criteria not improved was the delay between the time of antibiotic infusion and the beginning of surgery (organisational constraints). The routine use of antibiotic kits allowed to remove any antibiotic storage in the operating room and to improve the medical prescription's follow up through a computerised information system. With the kits, the number of different antibiotics used in the operating room decreases from 28 to 8. The complete accordance to the guidelines increases from 75% to 87% in the tsSAPKs group (p<0.01). Discussion The implementation of SAPKs « by type of surgery » allowed to improve the level of conformity to the guidelines. This sustainable process (since 2005) ensures the mandatory (legal issue) follow up of the prescriptions of antibiotics. Contexte L'antibioprophylaxie (ABP) est un des moyens essentiels de prévention des infections du site opératoire. La conso
设置外科抗生素预防是预防手术部位感染(ssi)的关键工具之一,需要根据具体的指导方针进行优化。手术室的抗生素消耗量几乎占医院抗生素总费用的30%,因此是提高整体抗生素使用的主要目标。个性化外科抗生素预防包(SAPKs)的实施与指南依从性的提高(82%的一致性)有关然而,这些工具包与额外的工作负荷相关联,损害了它们在日常实践中的使用。这里介绍的过程的目的是从个性化到sapk“按手术类型”,使sapk的实施更容易和可持续,而不损害其效率。程序包是在医院药房制作的(按照法国麻醉学会(SFAR)指南)。它们是单独的小纸袋,包括试剂盒和抗生素的标签(名称和剂量,如何使用)。每周五由医院药房更新一周抗生素的分配(使用位于康复室的滚动壁橱进行全空替换)。为了评估这一过程的影响,我们设计了一项暴露-非暴露前瞻性研究(内脏和骨科手术),定义了两组:非暴露患者使用自由处方的外科抗生素预防(fpSAPKs)和“按手术类型”(tsSAPKs)。结果共纳入420例患者。两组在手术类型(骨科33%,内脏66%)、年龄、性别、ASA和Altemeier类别以及手术时间方面具有可比性。88%的fpsapk患者和90%的tssapk患者开了外科抗生素预防处方(p=ns)。抗生素预防使用要点评估结果显示,处方原因一致性(93% vs 86%, p=0.01)和所选药物一致性(88% vs 81%, p=0.04)均有显著提高。唯一没有改善的标准是抗生素输注时间和手术开始之间的延迟(组织限制)。常规使用抗生素包可以消除手术室中任何抗生素的储存,并通过计算机化信息系统改善医疗处方的随访。有了这些工具包,手术室使用的不同抗生素数量从28种减少到8种。tsSAPKs组完全符合指南的比例从75%增加到87% (p<0.01)。SAPKs“按手术类型”的实施可以提高对指南的符合性。这一可持续进程(自2005年以来)确保了抗生素处方的强制性(法律问题)跟进。抗生素预防(ABP)是一种有效的预防感染的方法。La consommation d 'antibiotique盟集团operatoire represente总统德30% de La consommation hospitaliere完全et de ce做represente联合国du bon使用des antibiotiques enjeu重要。La协定在法国巴黎的工具d 'ABP赋予个性par患者装饰音管儿子efficacite倒l 'application des referentiels德公司(82%)。1大多数的电子套件都是非常重要的,empêchant在日常使用中使用较少。但是,在最初的时候,我们可以看到,在最初的时候,我们可以看到,在最初的时候,我们可以看到,在最初的时候,我们可以看到,我们可以看到,在最初的时候,我们可以看到,我们可以看到,我们可以看到,我们可以看到,我们可以看到,我们可以看到,我们可以看到,我们可以看到,我们可以看到,我们可以看到,我们可以看到。方案:<s:1>医疗器械和医疗器械与<s:1>医疗器械和医疗器械与<s:1>医疗器械和医疗器械与医疗器械相关的医疗器械(<s:1>医疗器械和医疗器械相关的医疗器械和医疗器械)。医疗器械和医疗器械系统(SSPI)的医疗器械和医疗器械系统(SSPI)。Afin d 'evaluer l评估这个中篇小说的过程,而我们弥尼一个练习曲潜在暴露——非公开(Chirurgie Viscerale et Orthopedique)德两个的小组:非公开=处方libre de l 'ABP (ABPlibre)等公开=利用de工具包par指示chirurgicale (ABPkit)。其中包括420名患者。两组患者的可比性分别为le型(矫正型33%,矫正型66%)、ge型(性别)、ASA、Altemeier型(干预型)。同一ABP测试处方中,ABPlibre占88%,ABPkit占90% (p=ns)。根据模数和模数的不同,根据模数和模数的不同,根据模数和模数的不同,根据模数和模数的不同,根据模数和模数的不同,根据模数和模数的不同,根据模数和模数的不同,根据模数和模数的不同。Le seul parpartre non - amsamicolioise, ce qui - problem not - ciblicolioise, est Le dsamuise entre l'administration de l' antiqutique et l'切口外科手术(contresul parparolioise)。 ABPkits的实施消除了抗生素的批量库存,并通过集成在医院信息系统中的实时计算机化实现了处方的可追溯性。从26个分子到试剂盒前的abp,我们现在有8个分子。ABPkit组的总符合标准从75%增加到87% (p<0.01)。根据手术适应症使用试剂盒有助于提高对标准的总体依从性。该组织自2005年6月以来一直存在,确保抗生素处方的监管可追溯性,以及更好的管理(有效期…)。
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引用次数: 0
144 Improvement by the evaluation of professional practices of decision making of relative to the limitation or discontinuance of treatment (LATA) 144通过评估与限制或停止治疗相关的决策的专业实践来改进(LATA)
Pub Date : 2010-04-01 DOI: 10.1136/QSHC.2010.041624.26
Larché Jérôme, B. Masson, Pierre Cocquet, M. Piqué, Ginot Jean, J-Claude Gouiry
Literature shows that the decisions to limit or stop the therapeutic treatment of patients (LATA) concerns, in intensive care unit (ICU), 10% of adult patients admitted and over 50% of patients who died. The law of the 22nd of April 2005 (Law Leonetti) recognises the necessity to prevent the use of intensive medication (meaning an inadequate use of “prolonged artificial life support”), sharing of sensitive medical information with families and favours the intra-hospital ethical reflexion. An evaluation of professional practises (EPP) designed to improve the methods of decision-taking for LATA among Narbonne Hospital's ICU was implemented between June 2008 and November 2009. Founded on the principles of the Law Leonetti, an evaluation form on the practises of LATA was drafted in June 2008, containing five items: The advice of the medical and Para medical team is recorded and noted in the medical file. The advice of the consultant doctor is taken into consideration. The advice of proxy (family and friends) is taken into consideration. A record of evidence on decisions taken (traceability). The name and function of people who participated in the decision is written in the medical file. This form allowed primarily a retrospective analyse of patient's files that were part of limited or withdrawal of medical intervention (LATA) in 2007. This audit was followed in October 2008, within ICU, by a promotion and propagation of the principles of the Law Leonetti and the protocol to follow, for LATA decision-taking. A prospective audit was then taken from November 2008 to November 2009 to assess the impact and efficiency of these improvement actions on LATA decision-taking process. The principle results of this retrospective audit (n=26 patients) established that 58% of the files did not contain the advice of the medical team, 73% of files did not contain the advice of consulting doctor, 50% of cases did not contain the advice of close proxy and only 54% of the medical files showed some traceability of the decisions taken. And not one medical file showed the name of persons who took the decisions for LATA. After these results, distributed throughout the Narbonne Hospital's ICU, an information has been widespread to the staff in October 2008, on Law Leonetti and on the protocol foreseen for LATA decision-taking. From November 2008 until November 2009 a prospective audit was performed in ICU on LATA's policy decisions. Out of 27 medical files examined, traceability of the medical team and the advice of consulting doctors weres found in 96.3% (26 out 27 files), traceability of all other items was 100% of the medical files. The results of this EPP can be considered positive, with an improved medical management in delicate and sensitive medical conditions. They also favour a collective acceptance—by medical and paramedical staff involved in ICU—of these frequent decisions and their impact, and their heavy consequences for patients and their families. We also consi
文献显示,在重症监护病房(ICU),决定限制或停止患者的治疗(LATA)是10%的成年患者入院和超过50%的患者死亡的问题。2005年4月22日的法律(Leonetti法律)承认有必要防止使用强化药物(即不适当地使用"延长人工生命维持器"),与家属分享敏感医疗信息,并有利于医院内部的道德反思。2008年6月至2009年11月期间实施了一项专业实践评估(EPP),旨在改进纳博讷医院重症监护室LATA的决策方法。根据《莱奥内蒂法》的原则,于2008年6月起草了一份评估价局的业务评估表,其中包括五个项目:医疗和辅助医疗小组的建议被记录并记录在医疗档案中。会诊医生的建议被考虑在内。我们会考虑代理人(家人和朋友)的建议。对所作决定的证据的记录(可追溯性)。参与决策人员的姓名和职能都写在医疗档案中。该表格主要允许对2007年有限或撤销医疗干预(LATA)的一部分患者档案进行回顾性分析。在2008年10月的审计之后,在国际刑事法院内部,促进和宣传了《莱奥内蒂法》的原则和应遵循的协议,以供LATA决策。随后,从2008年11月至2009年11月进行了前瞻性审计,以评估这些改进措施对LATA决策过程的影响和效率。回顾性审计(n=26例)的主要结果确定,58%的档案不包含医疗团队的建议,73%的档案不包含咨询医生的建议,50%的病例不包含密切代理的建议,只有54%的医疗档案对所做的决定有一定的可追溯性。没有一份医疗档案显示了为LATA做决定的人的名字。这些结果在纳博内医院的重症监护室中分发之后,于2008年10月向工作人员广泛传播了关于Leonetti法和LATA决策预期议定书的信息。从2008年11月到2009年11月,ICU对LATA的政策决定进行了前瞻性审计。在检查的27份医疗档案中,有96.3%(27份文件中有26份)发现了医疗团队和咨询医生的建议的可追溯性,其他所有项目的可追溯性均为100%。这种EPP的结果可以被认为是积极的,在微妙和敏感的医疗条件下改善了医疗管理。他们还赞成集体接受这些频繁的决定及其影响,以及它们对病人及其家属的严重后果,包括icu的医务人员和辅助医务人员。我们还认为,在LATA作出决定之前,这些伦理反思的质量和分享可能会缓和相关的医疗法律风险。虽然仅在一个单位建立,但这些结果促使我们在纳邦医院的其他单位实施这一LATA决策协议。<s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> (LATA) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -2005年4月22日的通告("通告")("通告")- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -2008年6月和2009年11月,在纳博纳医院中心对目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标、目标和目标。basant En se苏尔Leonetti法则的对于我,一个卡片d”des检疫de拉塔病的疾病redigee En 2008年juin contenant 5项:1)L威de队报》医学研究院等para-medicale est等考虑图在档案;2) L'avis du m<s:1>决定顾问测试pris en compte;3) L'avis de la personne de con未婚妻(你的<s:1>家庭<s:2>个人健康档案)est pris en compte;4) La tra<s:1> abilabilit<e:1> de La danciision;5) Le nom et la功能des persones ayant participente(个人和组织的职能).(个人和组织的职能).(个人和组织的职能)他说:“我们对2007年在‘目标’上失败的患者的档案进行了回顾性分析。”2008年10月1日,审计和确定了<s:1> <s:1> <s:1> <s:1>生存协议和确定<s:1>生存协议和确定<s:1>生存协议和确定<s:1>生存协议和确定<s:1>生存协议和确定<s:2>生存协议。
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引用次数: 0
183 Program for the improvement of pain management in the CHU of Bordeaux. Impact on pain prevalance, patient satisfaction and the traceability of pain 183波尔多地区疼痛管理改进方案。对疼痛患病率、患者满意度和疼痛可追溯性的影响
Pub Date : 2010-04-01 DOI: 10.1136/QSHC.2010.041616.21
N. Robinson, F. Stark
Introduction—Objectives Bordeaux University Hospital has conducted a total quality improvement program about pain management. After several surveys it selected five quality indicators about pain management and organised the continuous collection of them by professionals. The indicators are patient satisfaction on pain management, patient information on pain management, pain traceability, pain prevalence and pain treatment existence. The objectives of this program and follow-up of a set of five indicators were to improve pain management in all the departments of Bordeaux University Hospital. Program The three steps of the program are the following: (1) diffusion of guidelines on pain management, (2) intranet framework constitution for indicators collection, and (3) project follow-up. Results The table shows the results of the indicators between 2006 and 2009 Table 2006 2007 2008 2009 Adults 1718 1972 1851 2250 Traceability (%) 53.4 59.9 61.9 60.3 Pain treatment (%) 57.5 59.9 61.9 60.3 Pain prevalence (%) 27.6 26.9 29.7 23.8 Pediatrics 219 194 170 315 Traceability (%) 45.2 72.2 67.7 51.7 Pain treatment (%) 50.7 45.9 49.4 47.8 Pain Prevalence (%) 31.3 21.4 8.6 18.4 The results show a lowering of pain prevalence, particularly in pediatrics and the improvement of pain traçability. Discussion Indicators are collected in routine. They allow comparisons about pain management quality. These indicators are simple, quick and reproductible. They allow to address priority about pain management action and the follow-up of these actions on quality of pain management. Introduction—objectifs Malgré les progrès de ces dernières années, la douleur reste un symptôme présent chez environ 1 patient sur 3 hospitalisé au CHU de Bordeaux. Le CLUD (comité de lutte contre la douleur) du CHU de Bordeaux dès sa mise en place (1998) a mené une enquête unique en France, établissant l'état des lieux de la prise en charge de la douleur (1999). Les objectifs étaient de décrire les modalités d'information, de diagnostic, de traitement et de suivi des patients douloureux et de décrire les résultats de cette prise en charge pour les patients douloureux. Cette enquête a été ensuite été étendue à 13 établissements de l'Aquitaine membre du CCECQA en 2000. Suite à cette première enquête, le CLUD s'est inscrit dans une démarche de recherche continue d'amélioration de la prise en charge de la douleur. En novembre 2003, une nouvelle enquête reposant sur la même méthodologie a été menée, dans le cadre des Etats Généraux de la douleur. Le CHU fait partie des établissements participants au projet COMPAQH. De plus, le CLUD travaille en commission dont l'une a pour thème l'évaluation par indicateurs de la Prise en charge (PEC) de la douleur. En partenariat avec le CCECQA 5 indicateurs ont été retenus pour le suivi de la PEC de la douleur: Satisfaction des patients vis-à-vis de la prise en charge de la douleur Information des patients sur la prise en
波尔多大学医院开展了疼痛管理的全面质量改进项目。经过几次调查,它选择了五个关于疼痛管理的质量指标,并组织专业人员持续收集这些指标。指标包括患者对疼痛管理的满意度、患者对疼痛管理的信息、疼痛可追溯性、疼痛患病率和疼痛治疗存在。该方案的目标和一套五项指标的后续行动是改善波尔多大学医院所有部门的疼痛管理。该方案的三个步骤是:(1)疼痛管理指南的传播;(2)指标收集intranet框架的构建;(3)项目跟踪。结果表2006年2007年2008年2009年成人1718 1972 1851 2250可追溯性(%)53.4 59.9 61.9 60.3疼痛治疗(%)57.5 59.9 61.9 60.3疼痛患病率(%)27.6 26.9 29.7 23.8儿科219 194 170 315可追溯性(%)45.2 72.2 67.7 51.7疼痛治疗(%)50.7 45.9 49.4 47.8疼痛患病率(%)31.3 21.4 8.6 18.4结果显示疼痛患病率有所下降。特别是在儿科和疼痛传导能力的改善。日常收集指标。它们允许对疼痛管理质量进行比较。这些指标简单、快速、可重复。它们允许解决疼痛管理行动的优先级以及这些行动对疼痛管理质量的后续行动。介绍-目的:马尔格力(malgraise)关于<s:1> <s:1> <s:1> <s:1>交换交换系统(<s:1>交换交换系统(symptôme))的方案,关于<s:1>交换交换系统(symptôme)的双重交换交换系统,1名病人,3家医院,波尔多(CHU de Bordeaux)。Le CLUD (comit<e:1> de lutte contre la douleur) du CHU de Bordeaux ddous se se en place (1998) a menmeneune enquête unique in France (1999), samabisant l' samuede de la prise en charge de la douleur(1999)。目标是将患者的信息、诊断、治疗和生存与患者的生活联系起来,将患者的生活与患者的生活联系起来,将患者的生活与患者的生活联系起来。Cette enquête a samatest ensuite samatest samatest . 13 samatissements de l'Aquitaine成员du CCECQA en 2000。Suite ccete premiires enquête, le cld’s'est incrist ' s danci.917 . com ' sanci.917 . com ' sanci.917 . com ' sanci.917 . com ' sanci.917 . com ' sanci.917 . com ' sanci.917 . com ' sanci.com/ com/2003年11月,有一项新规定enquête重新确定了même与<s:1> <s:1> - <s:1> - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -在COMPAQH项目中,Le CHU为所有参与者提供了有效的信息。此外,《公约》还规定,《公约》不应在《公约》中规定,在《公约》中规定了《公约》和《公约》的各项指标。在《中华人民共和国经济和社会保障委员会》的伙伴关系报告中,关于<s:1>化学武器和化学武器的<s:1>化学武器和化学武器的残留的5个指标:满意度des病人面对de la撬en电荷de la douleur信息des病人在la撬en电荷de la douleur Tracabilite de la douleur患病率de la douleur d存在一个traitement antalgique L的用处ce计划de recueil et de suivi de ces 5 indicateurs是改进质量的de la撬en de la douleur收费服务德参与du楚de波尔多最令人舒服。计划兵站1:修订et de recommandations pour la撬en la扩散电荷de la douleur兵站2:要用的东西都放用品网站内部网permettant le recueil des indicateurs关于网站内部网du楚,联合国工具包des indicateurs douleur疾病克里族倒permettre la saisie du recueil·德·多恩等用于immediat结果,l 'echelle du服务行动,du, ou de l 'etablissement。磁带3:mise en œuvre et suivi du project。在第一阶段,我的职业生涯中,我的职业生涯中,我的职业生涯中,我的职业生涯中,我的职业生涯中,我的职业生涯中,我的职业生涯中。在此之前,已确定的是,已确定的是,已确定的是,已确定的是,已确定的是,已确定的是,已确定的是,已确定的是,已确定的是。2006年1月,在“信息决定机构”和“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”、“信息决定机构”等。表1 . 2006年有关的各项指标。2006年2007年2008年2009年成年患者1718年1972年1851年2250年traabilit<e:1> (%) 53.4 59.9 61.9 60.3 prence ttt antitalgique (%) 57.5 59.9 61.9 60.3 prabilit<e:1>(%) 27.6 26.9 29.7 23.8患者patrie 219 194 170 315 prabilit<e:1> (%) 45.2 72.2 67.7 51.7 prence ttt antitalgique (%) 50.7 45.9 49.4 47.8 prvalence douleur(%) 31.3 21.4 8.6 18。 4结果显示,疼痛患病率显著下降,特别是在儿科,疼痛可追溯性改善。指标现在是例行的,可以进行比较,以判断护理的质量。其优点是使
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引用次数: 0
032 Risk cartography and professional practice in the management of severe sepsis and septic shock in Intensive Care Unit 重症监护室重症脓毒症和感染性休克管理的风险制图和专业实践
Pub Date : 2010-04-01 DOI: 10.1136/qshc.2010.041624.24
A. Barbe, Olivier Pichenot, V. Kostusiak, M. Philippe
Objectives In Intensive Care Unit (ICU), the epidemiological data show a high incidence of severe sepsis syndromes associated with a significant mortality rate. The quality and safety of care must be insured by a fast and adapted management. To ensure septic patients safety, an evaluation of the professional practices (EPP) coupled with a cartography of risks was conducted in the ICU of the French Hospital of Charleville-Mézières. The attempted objectives were to perform an inventory of the practices by taking into account the therapeutic aspects and the timing of care, and by analysing risks, in order to offer a plan for improvement of practices. Program During a 5 months period, a clinical audit and a clinical pathway were realised on 17 patients presenting a severe sepsis or a sepsis shock. The clinical audit included clinical data, haemodynamic, biological and antibiotic management modalities. To optimise the evaluation of this support, the clinical pathway included the EPP criteria at the 1st, the 6th, and the 24 h after diagnosis. The preliminary analysis of risks (PAR) allowed to define a cartography of dangerous situations (DS) according to gravity of the consequences (delay of care, impact on the organisation of the care, loss of chance, adverse effects) and to their likelihood (percentage of the patients presenting a severe sepsis). The hierarchical organisation of risks was realised according to three levels of approval of the risk (C1: acceptable, C2: admissible, C3: unacceptable). Results The results show an incidence of sepsis and sepsis shock of 10%, and a mortality rate of 35% among this population. In the clinical audit, four criteria were not fulfilled (conformity rate <60%) for example “antibiotic treatment” showing a critical threshold of 35%. The analysis of the clinical pathway reveals that none of the criteria was present for the 60% threshold with a critical threshold <35% for the SvO2 criteria and < 6% for the titration of fluid therapy. The PAR highlights the critical stage of care management (1 h: 40% of DS, and between 1 and 6 h: 38%) as well as the dangerous elements (clinical practices and technological equipments: 50% DS). The cartography of initial risks shows the following distribution of the DS: C1: 9%, C2: 38%, C3: 53%. The improvement plan contains 47 actions concerning organization, actors knowledge, investment, and quality indicators. The impact of the plan is measured by determining the residual criticality of identified scenarios stemming from the residual gravity of the consequences and their likelihood after establishment of the actions. This action plan allows removing unacceptable DS and considerably increases the number of acceptable situations from 9 to 60% (C1: 60%, C2: 40%, C3: 0%). Discussion The level of safety practice defined by the disappearance of the C3 risks, is applicable only if the actors know and apply actions of improvement. The motivation and the accompaniment of the professionals in
在重症监护病房(ICU),流行病学数据显示严重脓毒症综合征的高发病率与显著的死亡率相关。必须通过快速和适应的管理来保证护理的质量和安全。为了确保脓毒症患者的安全,在法国沙勒维尔-姆萨齐<e:1>医院的重症监护室对专业做法进行了评估,并绘制了风险地图。尝试的目标是通过考虑治疗方面和护理时间,并通过分析风险,对实践进行盘点,以便提供改进实践的计划。在5个月的时间里,对17例出现严重脓毒症或脓毒症休克的患者进行了临床审计和临床路径。临床审核包括临床数据、血流动力学、生物和抗生素管理方式。为了优化这种支持的评价,临床途径包括诊断后第1、第6和24小时的EPP标准。风险的初步分析(PAR)允许根据后果的严重性(延误护理、对护理组织的影响、失去机会、不利影响)及其可能性(出现严重败血症的患者百分比)定义危险情况的地图(DS)。风险的分层组织是根据风险的三个批准级别(C1:可接受,C2:可接受,C3:不可接受)来实现的。结果本组败血症及败血症休克发生率为10%,死亡率为35%。在临床审核中,有4项标准不符合(符合率<60%),例如“抗生素治疗”的临界阈值为35%。临床路径分析显示,60%阈值没有任何标准存在,SvO2标准的临界阈值<35%,液体治疗滴定的临界阈值< 6%。PAR强调护理管理的关键阶段(1小时:40%的DS, 1 - 6小时:38%)以及危险因素(临床实践和技术设备:50%的DS)。初始风险制图显示DS的分布如下:C1: 9%, C2: 38%, C3: 53%。改进计划包含47项行动,涉及组织、参与者知识、投资和质量指标。计划的影响是通过确定已确定情景的剩余临界性来衡量的,这些情景源于后果的剩余严重性及其在行动建立后的可能性。该行动计划允许消除不可接受的DS,并将可接受情况的数量从9%大幅增加到60% (C1: 60%, C2: 40%, C3: 0%)。C3风险消失所定义的安全实践水平,只有当参与者知道并采取改进措施时才适用。在这项降低风险的计划中,专业人员的激励和陪伴仍然是保证实践质量和安全的必经之路。风险的等级组织是一种管理工具,通过引入对患者后果的严重性标准,有助于争论投资的选择和请求。结论经济背景和对安全实践的研究促使ICU从业人员对其实践产生怀疑。实现对风险的评估和分析,可以定义和实施护理安全实践。定量方面,基于回顾性研究,再加上定性方面(由重力标准确定),可以确定行动对患者质量和安全的影响。EPP和风险制图相结合,可以研究危险情况的潜在原因,并制定行动计划。它的效率应该在2010年底用所有显示的行动的结果来评估。目的:研究了不同年龄的人与不同年龄的人、不同年龄的人、不同年龄的人、不同年龄的人、不同年龄的人、不同年龄的人、不同年龄的人。La qualit<s:1> et La ssamit<s:1> curit<s:1> des soins doit être sursusametae与accetetae相比,价格上涨更快。在沙勒维尔-米萨齐<e:1>医院中心的综合价值、在萨勒维尔-米萨齐<e:1>医疗中心的综合价值、在萨勒维尔-米萨齐<e:1>医疗中心的综合价值、在萨勒维尔-米萨齐<e:1>医疗中心的综合价值、在萨勒维尔-米萨齐<s:1>医疗保健中心的综合价值、在萨勒维尔-米萨齐<s:1>医疗保健中心的综合价值、在萨勒斯-米萨齐<s:1>医疗保健中心的综合价值、在萨勒斯-米萨齐<s:1>医疗保健中心的综合价值、在萨勒斯-米萨齐<s:1>医疗保健中心的综合价值。目的修复是德意识到联合国状况des lieux des实际她考虑'aspect therapeutique et la rapidite de撬en,等一个分析des个afin de申请人联合国计划d 'amelioration des实际应用。方案悬案5月,联合国审计诊所和化学诊所对17名患有严重脓毒症的患者进行了抽样调查。
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引用次数: 0
289 Improving safety of patient treated by vitamin K antagonists in geriatrics 289提高老年患者维生素K拮抗剂治疗的安全性
Pub Date : 2010-04-01 DOI: 10.1136/QSHC.2010.041624.73
C. Bussy, P. Ghiassi, C. Oasi, S. Pariel, S. Chauvelier, M. Sohane, J. Belmin
Background Vitamin K antagonists (VKA) are widely used in old patients with atrial fibrillation or venous thromboembolism. Safety is a major concern, especially in old patients. International normalised ratio (INR)>5 is associated with an increased risk of bleeding and is considered as a near miss error. Aim To reduce the incidence of episodes of INR>5 which occurred during the hospital stay of patients of a geriatric hospital ward exposed to VKA. Design: Intervention study, non randomised. Methods The study was done in five geriatric wards comprising acute, intermediate and long-term care beds of a French hospital. The intervention was conducted in one ward of the hospital. A structured teamwork among the medical staff of the geriatric ward was implemented from July to December, 2005. Twice monthly, the medical staff examined during a short meeting the cases of all the patients with INR>5 which occurred during the preceding weeks. The group discussed cases using a tool designed to identify prescribing errors in dose adjustment and/or INR monitoring. The approach was proactive in order to learn from errors and not punitive. The number of patients exposed to VKA and the number of episodes of INR>5 were recorded during a 12-month period before the intervention (2004–2005) and during the year following it in the intervention ward and in control wards (2006). Results In control wards, 60 episodes of INR>5 were recorded in the 267 patients (22.5%) receiving VKA in 2004–2005 and 56 episodes among the 263 (22.1%) in 2006. In the intervention ward, 22 episodes were recorded in the 72 patients (30.6%) in 2004-2005, and 16 episodes of INR>5 were recorded among the 92 patients (17.4%), corresponding to a significant decrease (−43.1%) as compared to control wards (–1.8%, p<10–4). Conclusion A structured teamwork focused on cases of INR>5 lessen the risk of VKA overdosage and might improve safety of anticoagulation. Learning from errors seems an efficient way to improve quality of care. Contexte Les antivitamines K (AVK) sont largement utilisées chez les patients âgés ayant une fibrillation auriculaire ou une maladie veineuse thromboembolique. La sécurité est une préoccupation majeure, en particulier chez les patients âgés. L'international normalised ratio (INR)>5 est associé à une majoration du risque de saignement et est considéré comme un événement critique. But Réduire l'incidence des épisodes d'INR>5 survenant pendant le séjour hospitalier chez les patient d'un service de gériatrie recevant des AVK. Type d'étude Interventionnelle non randomisée. Méthodes L'étude a été conduite dans 5 services hospitaliers de gériatrie comprenant des lits de court séjour, de soins de suite-réadaptation et soins de longue durée. L'intervention a été conduite dans un service de l'hôpital. Un travail structuré au sein de l'équipe médicale a été conduit de juillet à décembre 2005. Deux fois par mois, l'équipe médicale a examiné durant
背景维生素K拮抗剂(VKA)广泛应用于老年房颤或静脉血栓栓塞患者。安全性是一个主要问题,特别是对老年患者。国际标准化比率(INR)>5与出血风险增加相关,被认为是近漏诊误差。目的降低暴露于VKA的老年病房患者住院期间INR>5发作的发生率。设计:干预研究,非随机。方法在法国某医院的5个老年病房进行研究,包括急性、中期和长期护理床位。干预是在医院的一个病房进行的。2005年7月至12月,在老年病房的医务人员中实施了有组织的团队合作。医务人员每月两次在一次简短会议上检查前几周发生的所有INR>5的患者的病例。小组讨论了使用一种工具确定剂量调整和/或INR监测中的处方错误的病例。这种方法是主动的,以便从错误中吸取教训,而不是惩罚性的。在干预前的12个月期间(2004-2005年)和干预后的一年期间(2006年),在干预病房和对照病房记录了暴露于VKA的患者人数和INR>5的发作次数。结果2004-2005年在对照组病房接受VKA的267例患者中有60例(22.5%)发生INR>5, 2006年263例患者中有56例(22.1%)发生INR>5。在干预病房,2004-2005年72例患者中有22例(30.6%),92例患者中有16例INR>5(17.4%),与对照病房(-1.8%)相比,显著降低(- 43.1%),降低了VKA过量的风险,可能提高抗凝安全性。从错误中学习似乎是提高护理质量的有效方法。背景:抗维生素K (AVK)的使用范围广泛,可用于治疗心房纤颤、静脉血栓栓塞等疾病。不可抗力是指一种不可抗力的职业,特别是在不可抗力的职业中,尤其是在不可抗力的职业中。国际归一化比率(INR)>5,表明该比率大于5,表明该比率大于5,表明该比率大于5,表明该比率大于5。但是,在所有的病例中,只有在所有的病例中,只有在所有的病例中,只有在所有的病例中,只有在所有的病例中,只有在所有的病例中,只有在所有的病例中。干预型,非随机型。3 . 和/或···········L'intervention a sdames conduite dans un service de L 'hôpital。2005年1月1日,在一份文件中,将所有的薪金和薪金分别定为“薪金和薪金”。两个fois par mois, l' samquipe msamicale和examinise都是指在一个法庭上,一个法庭上,一个法庭上,一个法庭,一个法庭,一个法庭,一个法庭,一个法庭,一个法庭,一个法庭,一个法庭,一个法庭。该小组讨论了在处方中涉及剂量调整和对inr的监测的处方错误之前使用的药物。我的办法是积极主动的,但我不知道你犯了什么错误,也不惩罚你。“病人的名字”是指接触到的 武装分子和 武装分子和武装分子的名字”;“收集到的武装分子和武装分子的名字”;“收集到的武装分子的名字”;“收集到的武装分子的名字”(2004-2005年);“收集到的武装分子的名字”(2006年);“服务干预和服务contrôles”。在2004年至2005年期间,有60名患者(超过5名)和267名患者(占22.5%)在2004年至2005年期间,有56名患者和263名患者(占22.1%)在2006年期间接触了这些患者(占22.1%)。在服务干预中,2004-2005年期间,有22名患者接受了 材料材料和 材料材料和材料的治疗(30.6%),2006年,有16名患者接受了 材料材料和材料的治疗(17.4%),与其他服务相比,有显著减少(- 43.1%)(- 1.8%),减少了过量服用抗维生素K的风险,减少了过量服用抗维生素K的风险,减少了 材料和材料的风险)。在经济效益和质量问题上,经济伙伴关系中的错误包括经济效益和质量问题。在巴黎服务方面,工作会议类似于其他组织的工作会议。
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引用次数: 0
163 Management of shoulder pane in hemiplegic patients in a multidisciplinary team 163一个多学科团队对偏瘫患者肩关节裂的处理
Pub Date : 2010-04-01 DOI: 10.1136/qshc.2010.041624.53
T. Myriam, R. Olivier, Kermarrec Solange
The management of pain is a public health issue. It's a part of the institutional project of care of the University Hospital of Brest. Shoulder pain affects 15 to 70% of hemiplegic patients after stroke admitted to Physical and Rehabilitation Medicine (PRM) units. It has a negative impact on the PRM programs and on the functional results after upper limb rehabilitation. In the absence of consensus treatment, prevention outweighs support. Hemiplegic stroke patients represent 70% of recruitment of the PRM neurological unit. A program of quality enhancement of clinical practice was conducted (using the resolution of problems) in 2006. The objective was the assessment of the incidence and the improvement of the management of shoulder pain. Malfunctions in all stages of care have been identified (prevention, information, diagnosis, treatment…) and led to define different actions for improvement: Preventive measures: staff training (the training program was held in 2007), education of patients and their relatives (practical training of upper limb mobilisation, positioning, transfers, writing of a booklet of education), purchasing equipment after identification, training healthcare teams upstream services (training provided in 2007 and early 2008) and information of external speakers (disseminate the brochure of education) Assessment or risk factors: screening of the pain and risk factors at enrolment (target entry sheet for nurses), regular assessment group summary Traceability or the treatment: monitoring therapeutic actions in a computerised medical record network Coordination of care: development of a protocol ‘prevention and management of shoulder pain of hemiplegic patients’ Monitoring indicators have been defined: Care records (entry sheet for nurses, opening the specific computer file after diagnosis, initiation of a target in targeted transmission of care) Assessment of staff knowledge (knowledge level before and after training) Changing the number of patients suffering from hemiplegic shoulder pain before, during, 1 and 3 years after the program. With a number of hemiplegic relatively stable over 4 years (between 93 and 101 per year), results show: In 2005 and 2006 (before and during the process), respectively 13% and 14% of patients had shoulder pain, 66 and 57% were acquired during their stay. In 2007 a 57% reduction in the number of shoulder pain was observed (ie 8% of the total number of hemiplegic patients hospitalised in the unit) of which 26% were acquired during their stay. In 2009, 14% of patients had shoulder pain and 50% were acquired during their stay. Initially, apart from improved knowledge in particular on the importance of prevention, care coordination and formalisation of practice, this program of quality improvement has significantly reduced the number of patients suffering from shoulder pain during their stay in the PRM unit. Early detection, recorded comprehensively, enables besides an immediate management of the patient in
疼痛的管理是一个公共卫生问题。这是布雷斯特大学医院医疗机构项目的一部分。肩痛影响15%至70%的中风后偏瘫患者入院的物理和康复医学(PRM)单位。它对PRM方案和上肢康复后的功能结果有负面影响。在缺乏共识治疗的情况下,预防重于支持。偏瘫性脑卒中患者占PRM神经学单元招募患者的70%。2006年实施了一项提高临床实践质量的计划(利用问题的解决)。目的是评估肩痛的发生率和管理的改进。已查明护理各个阶段的故障(预防、信息、诊断、治疗……),并确定不同的改进行动:工作人员培训(培训方案于2007年举行)、对患者及其家属的教育(上肢活动、定位、转移、编写教育小册子的实际培训)、识别后购买设备、培训医疗团队上游服务(2007年和2008年初提供培训)和对外扬声器的信息(分发教育小册子)。在入组时对疼痛和危险因素进行筛查(护士的目标输入表),定期评估小组总结治疗的可追溯性:在计算机化医疗记录网络中监测治疗行动护理协调:制定“偏瘫患者肩部疼痛的预防和管理”方案监测指标已被定义:护理记录(护士录入表,诊断后打开特定的电脑文件,在针对性的护理传递中启动一个目标)员工知识评估(培训前后的知识水平)改变项目前、期间、1年和3年患偏瘫肩痛的患者人数。在4年的时间里,偏瘫患者的数量相对稳定(每年93 - 101例),结果显示:2005年和2006年(手术前和手术中),分别有13%和14%的患者出现肩关节疼痛,66%和57%的患者在住院期间出现肩关节疼痛。2007年,观察到肩部疼痛的人数减少了57%(即在该部门住院的偏瘫患者总数的8%),其中26%是在住院期间获得的。2009年,14%的患者有肩痛,50%是在住院期间获得的。最初,除了提高对预防、护理协调和实践正规化的重要性的认识外,这一质量改进方案显著减少了在PRM病房住院期间患肩痛的患者人数。全面记录的早期检测除了可以在诊断为阳性的情况下立即对患者进行管理外,还可以发现有发生这种疼痛风险的患者,并有助于实施有重点和严格的预防方案。质量改进方案强烈倾向于通过对保健小组、病人及其家属的教育进行预防。实践协议的正规化已产生了积极的初步影响。对新护理人员的培训、入院时的筛查和监测方案仍在继续。3年的结果令人失望。在2008年和2009年,40%的护理员获得了续签。培训的重点是新员工,在初始阶段之后,整个团队没有采取任何行动。这些结果表明,支持计划的教育和正规化需要为员工保持积极的教育政策,这种政策不断发展,并在多种行动中不断寻求。在布列斯特医院中心-大学(CHU)的项目机构中,负责公共医疗服务中心的管理工作。双份的薪金薪金影响15%的薪金薪金,70%的薪金薪金影响15%的薪金薪金,70%的薪金薪金影响15%的薪金薪金,70%的薪金薪金影响15%的薪金薪金,70%的薪金薪金影响19%的薪金薪金。这是一项影响到所有人的薪金和薪金的方案,包括所有人的薪金和薪金,所有人的薪金和薪金。在没有达成一致意见的情况下,就会有意外发生。leshmimiplacimgiques repraciment 70% du招聘du service de MPR neurogique du CHU。2006年1月1日,《职业实务评估》(EPP)将《关于<s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1> <s:1>(或)与<s:1> <s:1>(或)与<s:1>(或)与<s:1>)与<s:1>(或)与<s:1>)与<s:1>(或)与<s:1>)与<s:1>(或)与<s:1>)与<s:1>(或)与<s:1>)与<s:1>(或) 注意到所有护理阶段(预防、信息、诊断、治疗等)的功能障碍,并确定了各种改进措施:工作人员培训(2007年提供的培训方案),病人及其家属的教育(动员、安装、转移、编写教育手册的实际培训),普查后购买必要的设备,前端培训的护理团队的服务(提供的培训方案于2007年和2008年初)和外部(信息传播教育小册子)评价:这种疼痛筛查及危险因素的患者入院(macro-cible-entrée)、综合行动小组,定期进行跟踪治疗:护理协调行动:起草“偏瘫患者肩痛的预防和管理”方案监测指标定义如下:情报档案评价护理(macro-cible入境、自诊断、开设计算机档案的开放通信中的对象定向)评估人员知识培训知识水平(前/后)偏瘫的患者数变化之前、期间、肩痛患者1年和3年之后,《专家。在4年的时间里,偏瘫患者的数量相对稳定(每年93 - 101例),分析结果显示:2005年和2006年(手术前和手术中),分别有13%和14%的患者出现肩痛,其中66%和57%是在服务中获得的。2007年,观察到肩痛减少了57%(占住院偏瘫患者总数的8%),其中26%是在住院期间获得的。2009年,14%的患者出现肩痛,其中50%是在服务中获得的。最初改善而那边的知识,包括关于预防的重要性,协调医疗和护理做法正式化的议定书(此举)、质量改进数量大大减少了患者的肩部处逗留期间,在革。提供全面信息的早期筛查,以及在诊断为阳性的情况下立即对患者进行管理,可以筛查有可能出现这种疼痛的患者,并以有针对性和严格的方式实施必要的预防措施。通过对护理团队、患者及其周围环境的教育,以及将实践正规化到协议中,这种EPP的重点是预防,因此产生了初步的积极影响。继续开展培训活动、入院筛选和方案监测。3年的结果令人失望。在2008年和2009年,40%的护理和康复团队得到了更新。培训针对的是新员工,在初始阶段之后没有对整个团队采取行动。这些结果似乎表明,教育行动和预防护理的正规化需要对不断变化的医院工作人员保持积极的教育政策,并不断要求他们采取多种行动。
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引用次数: 0
108 A public health intervention program to improve the initial management of soft tissue sarcomas 108改善软组织肉瘤初期治疗的公共卫生干预计划
Pub Date : 2010-04-01 DOI: 10.1136/QSHC.2010.041608.6
C. Bellera, B. Bui, C. Chevreau, É. Bauvin, F. Pelissier, P. Grosclaude, M. Savès, E. Bompas, S. Albert, S. Mathoulin-Pélissier
Context Soft tissue sarcomas (STS) are rare tumours. In France, STS is estimated to represent about 1% of all cancers, the true incidence of which remains unknown. Management of STS is particularly difficult due to the initial diagnosis which is complex (more than 50 histological subtypes). Moreover, initial surgery is often inappropriate as surgery is usually performed before biopsy resulting in complex decisions once STS is histological proven. Objectives A quasi-experimental before/after study (with control region) was implemented to set up and evaluate a public health intervention aimed at improving the quality of the initial management of STS (diagnosis and surgery). Additional objectives involved measuring the impact of this intervention, exploring factors associated in variations in the quality of STS management, and estimating STS incidence rate. Program The program was implemented in collaboration with the French Sarcoma Group (FSG), regional cancer registries and cancer regional networks. It involves five regions (covering 20% of the French population). This study was initiated in November 2006 and involves three phases. In the first phase (November 2006 to December 2007), information on STS cases diagnosed during this period was collected. Between January 2008 and October 2008, the public health program was implemented in four regions (the fifth region serves as a control), and involved two distinct actions: (1) written information campaign directed towards all relevant practitioners, and (2) oral communications in dedicated meetings by opinion leaders. Finally, information on STS cases diagnosed after this ‘action’ period was collected. Based on available incidence data, we anticipated that 300 STS cases per year would be recruited. As we were interested in evaluating the quality of STS management before and after the program, a preliminary step involved validating quality indicators (QIs) for cancer care. As such, we assessed which QIs were the most relevant to evaluate the quality of the management of STS. To validate QIs, a Delphi consensus method was set up. Based on Good Clinical Practices and a literature review, we prepared a set of 25 QIs, and relied on a panel of advisory FSG experts (n=19) from multiple medical specialities. We chose to measure the main impact of both actions (diagnosis + surgery) using a composite criterion focussing on three steps of initial management (imaging diagnosis, surgery, and multidisciplinary meeting), since these are directly associated with survival. Results in Terms of Clinical Impact Regarding QIs, consensus was reached for 23 items, with perfect consensus for 9 QIs (eg, the need for multidisciplinary management teams, appropriate surgical biopsy techniques). During the actions phase in the four concerned regions (one region was the control) about 16 000 written information (in the form of one double-sided page) were sent to practitioners; 18 meetings allowed us to increase awareness of about
背景:软组织肉瘤是一种罕见的肿瘤。在法国,STS估计约占所有癌症的1%,其真实发病率尚不清楚。由于初始诊断复杂(超过50种组织学亚型),STS的治疗尤其困难。此外,最初的手术通常是不合适的,因为手术通常在活检之前进行,一旦STS得到组织学证实,就会导致复杂的决定。目的采用准实验的前后对照研究(带对照区),建立和评价公共卫生干预措施,以提高STS(诊断和手术)的初始管理质量。其他目标包括测量这种干预措施的影响,探索与STS管理质量变化相关的因素,以及估计STS发病率。该方案是与法国肉瘤集团(FSG)、区域癌症登记处和癌症区域网络合作实施的。它涉及五个地区(占法国人口的20%)。这项研究于2006年11月展开,共分三个阶段。在第一阶段(2006年11月至2007年12月),收集在此期间诊断的STS病例资料。2008年1月至2008年10月,在四个地区实施了公共卫生方案(第五个地区作为对照),涉及两项截然不同的行动:(1)针对所有相关从业人员的书面宣传运动,以及(2)意见领袖在专门会议上进行口头交流。最后,收集了在这一“行动”期间诊断出的STS病例的信息。根据现有的发病率数据,我们预计每年将招募300例STS病例。由于我们对评估项目前后STS管理的质量很感兴趣,初步步骤包括验证癌症治疗的质量指标(QIs)。因此,我们评估了哪些质量指标与评估STS管理质量最相关。为了验证质量指标,建立了德尔菲共识法。基于良好临床实践和文献综述,我们编制了一套25个QIs,并依赖于来自多个医学专业的FSG咨询专家小组(n=19)。我们选择使用一个综合标准来衡量这两种行动(诊断+手术)的主要影响,该标准侧重于初始管理的三个步骤(影像学诊断、手术和多学科会议),因为这些与生存直接相关。在质量指标方面,23项达成共识,其中9项达成完全共识(如需要多学科管理团队、合适的手术活检技术)。在四个相关区域(一个区域为对照)的行动阶段,向从业者发送了约16000份书面信息(以双面纸的形式);18次会议让我们提高了大约500名从业者的意识。在研究结束前一个月,五个地区共纳入了858例病例(420例处于“之前”阶段)。初步结果表明,我们可以衡量一个地区(210例)的主要终点(基于综合标准的STS管理质量)。数据显示STS初始管理质量绝对提高10%(相对提高50%)。此外,2007年基于两个地区(269例)的初步数据表明,法国人口标准化发病率为每10万居民4.14例(欧洲人口标准化发病率为每10万居民4.03例)。讨论(观点)和结论初步发现提示STS的发生率被低估了。相关的质量指标将用于评估公共卫生计划,这将使我们能够(1)了解目前管理STS患者的做法;(2)评估简单的行动是否能改善实践。我们的结果需要与所有实施该计划的地区的完整数据进行确认,并与对照地区进行比较。2010年,一个临床和病理肉瘤网络将在法国实施(由法国国家研究所支持的罕见肿瘤网络),我们的最终结果将与STS管理的国家行动相关。组织肉瘤(Les sarcomes des tissus moous, STM)是一种罕见的肿瘤。在法国,它代表了大约1%的癌症,比其他的发病率更低。由于诊断的初始复杂性(加上50种不同类型的组织学),leleprise en charge是一种特殊的诊断困难。再加上,la chirurgie initiale est souvent不适当的渡假期(不适当的渡假期);再加上复杂的渡假期(不适当的渡假期)(不适当的渡假期)。
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引用次数: 0
期刊
Quality and Safety in Health Care
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