Estuarine environments have become crucial in coastal areas nowadays. Mangrove swamps, mudflats and related estuarine environments provide a habitat for animals and encourage plant growth. For the people of coastal areas, estuaries are one of the vital sources of food and other economic activity. The imbalance in the quality and quantity of Estuarine water in terms of its physicochemical parameters causes adverse effects on marine life. In the present study, an attempt has been made to estimate the physicochemical properties of the estuarine water of Mithbav tidal mud flats (downstream part) of coastal Maharashtra. Several methods have been used to evaluate the variations in physical and chemical properties of estuarine water in Mithbav including standard water testing,1 the titration method and Winkler's method. Salinity, turbidity, pH, total hardness, DO, TDS, EC, nitrate, fluoride, phosphate, ammonium, magnesium, calcium, carbonate, chloride, sodium, potassium and sulphate were examined for the seven cross-sectional sites of Mithbav estuarine water. Some parameters show levels of contamination that exceed the maximum limit. For instance, during the post-monsoon season, the average value of dissolved oxygen (DO) was recorded as 11.57mg/L whereas it has been recorded as 8.07mg/L during the summer season. The total dissolved solids (TDS) showed an average increase from 141.54 to 348.57ppt between pre and post-monsoon seasons. The electrical conductivity (EC) also increased from 45558.17μ S/Cm to 31445.85 μ S/Cm respectively from the dry to the wet season. The fluoride levels during the post-monsoon season ranged from 1.07 mg/L at CS-1 to 4.2 mg/L at CS-6. The study shows that the Mithbav coastal ecosystem and nearby areas are at significant risk of contamination from physiochemical parameters that could harm the environment.
{"title":"Estimation of Physicochemical Properties in the Estuarine Water of Mithbav Tidal Mud Flats (Downstream Part), Coastal Maharashtra","authors":"J.B. Sapkale, T.R. Jamadar, S.J. Sapkale, G.S. Shinde","doi":"10.25303/2710rjce010020","DOIUrl":"https://doi.org/10.25303/2710rjce010020","url":null,"abstract":"Estuarine environments have become crucial in coastal areas nowadays. Mangrove swamps, mudflats and related estuarine environments provide a habitat for animals and encourage plant growth. For the people of coastal areas, estuaries are one of the vital sources of food and other economic activity. The imbalance in the quality and quantity of Estuarine water in terms of its physicochemical parameters causes adverse effects on marine life. In the present study, an attempt has been made to estimate the physicochemical properties of the estuarine water of Mithbav tidal mud flats (downstream part) of coastal Maharashtra. Several methods have been used to evaluate the variations in physical and chemical properties of estuarine water in Mithbav including standard water testing,1 the titration method and Winkler's method. Salinity, turbidity, pH, total hardness, DO, TDS, EC, nitrate, fluoride, phosphate, ammonium, magnesium, calcium, carbonate, chloride, sodium, potassium and sulphate were examined for the seven cross-sectional sites of Mithbav estuarine water. Some parameters show levels of contamination that exceed the maximum limit. For instance, during the post-monsoon season, the average value of dissolved oxygen (DO) was recorded as 11.57mg/L whereas it has been recorded as 8.07mg/L during the summer season. The total dissolved solids (TDS) showed an average increase from 141.54 to 348.57ppt between pre and post-monsoon seasons. The electrical conductivity (EC) also increased from 45558.17μ S/Cm to 31445.85 μ S/Cm respectively from the dry to the wet season. The fluoride levels during the post-monsoon season ranged from 1.07 mg/L at CS-1 to 4.2 mg/L at CS-6. The study shows that the Mithbav coastal ecosystem and nearby areas are at significant risk of contamination from physiochemical parameters that could harm the environment.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study, an endophytic actinomycetes strain of Streptomyces viridodiastaticus strain MGR23 was isolated from the roots of the medicinal plant Centella asiatica. The biosynthesized Ag-NPs were characterized using UV-Vis spectroscopy, Fourier transform infrared (FT-IR), Scanning electron microscopy (SEM), X-ray diffraction (XRD) and Zeta potential, which confirmed the successful formation of crystalline, spherical silver nanoparticles. Biosynthesized AgNPs significantly inhibited and reduced the growth of medically important survival microorganisms (Streptomyces viridodiastaticus MGR 23 against Streptomyces toxytricini D2, Acidothermus cellulolyticus CA16, Streptomyces sp. MGR 21, Aciditerrimonas ferrireducens SM7 and Streptomyces tritici D5). The biosynthesized Ag-NPs exhibited broad-spectrum antihelminthic activity. Our data elucidated that the biosynthesized Ag-NPs had a highly cytotoxic effect against the cancerous L6 cell line under in vitro conditions, revealing a maximum IC50 value of 1.0 μg/mL and no known anticancer drug was used as a positive regulation. AgNPs have a remarkable synergistic impact that points to their considerable potential in nanomedicine for future clinical use as a combination therapy.
{"title":"Microbial mediated Synthesis and characterization of Ag Nanoparticles and its Synergistic impact on Actinobacterial, Anticancer and Antihelminthic activity","authors":"Gomathi Manoharan, Suresh Kumarasamy, Muthusamy Ranganathan","doi":"10.25303/2710rjce1050114","DOIUrl":"https://doi.org/10.25303/2710rjce1050114","url":null,"abstract":"In this study, an endophytic actinomycetes strain of Streptomyces viridodiastaticus strain MGR23 was isolated from the roots of the medicinal plant Centella asiatica. The biosynthesized Ag-NPs were characterized using UV-Vis spectroscopy, Fourier transform infrared (FT-IR), Scanning electron microscopy (SEM), X-ray diffraction (XRD) and Zeta potential, which confirmed the successful formation of crystalline, spherical silver nanoparticles. Biosynthesized AgNPs significantly inhibited and reduced the growth of medically important survival microorganisms (Streptomyces viridodiastaticus MGR 23 against Streptomyces toxytricini D2, Acidothermus cellulolyticus CA16, Streptomyces sp. MGR 21, Aciditerrimonas ferrireducens SM7 and Streptomyces tritici D5). The biosynthesized Ag-NPs exhibited broad-spectrum antihelminthic activity. Our data elucidated that the biosynthesized Ag-NPs had a highly cytotoxic effect against the cancerous L6 cell line under in vitro conditions, revealing a maximum IC50 value of 1.0 μg/mL and no known anticancer drug was used as a positive regulation. AgNPs have a remarkable synergistic impact that points to their considerable potential in nanomedicine for future clinical use as a combination therapy.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abir Ghamiaa, Zainab Oshah, Asra Al Shak, Esam Elhefian
Retama raetam is widespread in North Africa and considered to be a medicinal plant in folk treatment besides its importance as feed for livestock. It has been used as herbal remedy for healing several ailments like diarrhea, skin rash, sore throat, rheumatism, fever and injury sterilization. This study was conducted to estimate the medicinal and nutritional values of R. reatam plant by determining some essential contents, minerals, vitamin C and preliminary phytochemical compounds in its leaves. The primary analysis showed that the pH value of water extract was 7.18 ± 0.03 while the percentages of essential contents in leaves were 50.83 ± 1.04 crude fiber, 12.33 ± 0.76 crud lipids, 6.02 ± 0.01 crude protein, 5.00 ± 0.00 total ash content, 10.00 ± 0.00 ash soluble in water, 5.00 ± 0.00 ash insoluble in acid and 19.67 ± 0.58 moisture content. Primary tests of the crude aqueous extract revealed the presence of tannins , saponines, alkaloids flavonoids, glycosides, resins, terpenoids and steroids, while the ethanolic extract showed positive results for tannins, alkaloids, flavonoids, glycosides, terpenoids and steroids, but negative results for saponines and resins. The percentages of phytochemical compounds in the air dried leaves powder were 5.67 ± 0.58 tannins, 10.42 ± 0.72 saponines, 8.33 ± 0.76 alkaloids and 9.80 ± 1.13 flavonoids. The amounts of minerals and vitamins (mg/100) that were determined in the R. raetam dried leaves powder were 333.75 ± 1.77 potassium, 501.25 ± 1.77 sodium, 235.50 ± 6.36 magnesium, 500.00 ± 0.00 calcium and 35.33 ± 0.29 vitamin C. The obtained results prove the traditional medicinal use of R. raetam in North and East Mediterranean regions. In addition, knowing the amounts of the essential components and bioactive compounds may help in the preparation of the exact dosages for the treatment of diseases or for livestock feeding.
{"title":"Qualitative and Quantitative Phytochemical Analysis of Retama raetam (forssk) Leaves","authors":"Abir Ghamiaa, Zainab Oshah, Asra Al Shak, Esam Elhefian","doi":"10.25303/2710rjce067071","DOIUrl":"https://doi.org/10.25303/2710rjce067071","url":null,"abstract":"Retama raetam is widespread in North Africa and considered to be a medicinal plant in folk treatment besides its importance as feed for livestock. It has been used as herbal remedy for healing several ailments like diarrhea, skin rash, sore throat, rheumatism, fever and injury sterilization. This study was conducted to estimate the medicinal and nutritional values of R. reatam plant by determining some essential contents, minerals, vitamin C and preliminary phytochemical compounds in its leaves. The primary analysis showed that the pH value of water extract was 7.18 ± 0.03 while the percentages of essential contents in leaves were 50.83 ± 1.04 crude fiber, 12.33 ± 0.76 crud lipids, 6.02 ± 0.01 crude protein, 5.00 ± 0.00 total ash content, 10.00 ± 0.00 ash soluble in water, 5.00 ± 0.00 ash insoluble in acid and 19.67 ± 0.58 moisture content. Primary tests of the crude aqueous extract revealed the presence of tannins , saponines, alkaloids flavonoids, glycosides, resins, terpenoids and steroids, while the ethanolic extract showed positive results for tannins, alkaloids, flavonoids, glycosides, terpenoids and steroids, but negative results for saponines and resins. The percentages of phytochemical compounds in the air dried leaves powder were 5.67 ± 0.58 tannins, 10.42 ± 0.72 saponines, 8.33 ± 0.76 alkaloids and 9.80 ± 1.13 flavonoids. The amounts of minerals and vitamins (mg/100) that were determined in the R. raetam dried leaves powder were 333.75 ± 1.77 potassium, 501.25 ± 1.77 sodium, 235.50 ± 6.36 magnesium, 500.00 ± 0.00 calcium and 35.33 ± 0.29 vitamin C. The obtained results prove the traditional medicinal use of R. raetam in North and East Mediterranean regions. In addition, knowing the amounts of the essential components and bioactive compounds may help in the preparation of the exact dosages for the treatment of diseases or for livestock feeding.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Lingappa, Ananda Sindhe, Horti Sneha, Nabeela Begum, Mahesh Ratkal
Nowadays, water pollution is one of the major problems which the world is facing. Many factors are responsible for water pollution, among the various reasons, one of the major reason is the dyes released from the textile industry, as they contains numerous numbers of chemicals and heavy metals which affect the water and its habitats which are responsible for health problems in humans like cancer and other diseases in humans. In order to control this, elimination of azo dyes which is being released from the textile industries is necessary. In order to eliminate this, biological approach has been applied. In the present investigation, we isolated around 5 different bacterial strains from the textile effluents collected from industrial area of Solapur, Maharashtra. India in which the strain KL (SN) was found to decolorize the malachite green upto 40mg/1000ml with a 70.39% decolourization at a temperature of 280C and at a pH of 7 at 120 rpm for 4 days which was found to be highest than other strains. Further the strain KL (SN) was found to have 99.9% similarity with Tistrella mobilis.
{"title":"Bio-degradation of Azo dye by the Bacteria isolated from Textile Industry Effulent of Solapur district","authors":"K. Lingappa, Ananda Sindhe, Horti Sneha, Nabeela Begum, Mahesh Ratkal","doi":"10.25303/2710rjce027031","DOIUrl":"https://doi.org/10.25303/2710rjce027031","url":null,"abstract":"Nowadays, water pollution is one of the major problems which the world is facing. Many factors are responsible for water pollution, among the various reasons, one of the major reason is the dyes released from the textile industry, as they contains numerous numbers of chemicals and heavy metals which affect the water and its habitats which are responsible for health problems in humans like cancer and other diseases in humans. In order to control this, elimination of azo dyes which is being released from the textile industries is necessary. In order to eliminate this, biological approach has been applied. In the present investigation, we isolated around 5 different bacterial strains from the textile effluents collected from industrial area of Solapur, Maharashtra. India in which the strain KL (SN) was found to decolorize the malachite green upto 40mg/1000ml with a 70.39% decolourization at a temperature of 280C and at a pH of 7 at 120 rpm for 4 days which was found to be highest than other strains. Further the strain KL (SN) was found to have 99.9% similarity with Tistrella mobilis.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lal Chand Yadav, H. Jaimini, K. Meena, R.C. Meena, S.L. Meena
Eriochrome Black-T (EBT) is a commonly used textile dye. It is a harmful organic molecule and is also present in textile effluent. The photocatalytic degradation has been studied using MBIR Dowex-1×8 as the photocatalyst. Some parameters such as pH, light intensity, the amount of photocatalyst and initial dye concentration were also studied. At room temperature at pH 7.5, the optimal degradation of Eriochrome Black-T dye (30 mg/L) was observed in about 210 minutes and the photo catalyst load was 2.0 gm. The kinetic study related to the photocatalytic degradation of EBT followed first order kinetics where the rate constant is 2.11x10-2 min-1. This catalyst can degrade dye molecules and can recover transparent water from coloured textile effluent in few hours of treatment.
{"title":"Photocatalytic Degradation of Eriochrome Black-T Dye by Immobilized Dowex-1x8","authors":"Lal Chand Yadav, H. Jaimini, K. Meena, R.C. Meena, S.L. Meena","doi":"10.25303/2710rjce088095","DOIUrl":"https://doi.org/10.25303/2710rjce088095","url":null,"abstract":"Eriochrome Black-T (EBT) is a commonly used textile dye. It is a harmful organic molecule and is also present in textile effluent. The photocatalytic degradation has been studied using MBIR Dowex-1×8 as the photocatalyst. Some parameters such as pH, light intensity, the amount of photocatalyst and initial dye concentration were also studied. At room temperature at pH 7.5, the optimal degradation of Eriochrome Black-T dye (30 mg/L) was observed in about 210 minutes and the photo catalyst load was 2.0 gm. The kinetic study related to the photocatalytic degradation of EBT followed first order kinetics where the rate constant is 2.11x10-2 min-1. This catalyst can degrade dye molecules and can recover transparent water from coloured textile effluent in few hours of treatment.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T.M. Somanatha, G. Krishnaswamy, R. Nayana, J. Nayana, R. Bhavana, G. Shivaraj, S. Sreenivasa, Prakash M. Shet
In the present investigation, Schiff bases (SBs) bearing 1, 2, 3-triazole and furan motif were synthesized through condensation reaction via conventional approach (Route-A) and solvent free approach (Route-B). It has been found that route-B is efficient since it is eco friendly with short reaction time and satisfactory yield than route-A. The structure and formation of targeted Schiff bases (SBs) were confirmed by different spectroscopic techniques (1H NMR, 13C NMR and Mass). Finally, in vitro antimicrobial screening result revealed that the synthesised SBs derivatives may act as moderate antimicrobial agents.
{"title":"New 1, 2, 3-triazole-Furan Scaffold Schiff bases: Design, Synthesis, Characterization and biological studies","authors":"T.M. Somanatha, G. Krishnaswamy, R. Nayana, J. Nayana, R. Bhavana, G. Shivaraj, S. Sreenivasa, Prakash M. Shet","doi":"10.25303/2709rjce0107","DOIUrl":"https://doi.org/10.25303/2709rjce0107","url":null,"abstract":"In the present investigation, Schiff bases (SBs) bearing 1, 2, 3-triazole and furan motif were synthesized through condensation reaction via conventional approach (Route-A) and solvent free approach (Route-B). It has been found that route-B is efficient since it is eco friendly with short reaction time and satisfactory yield than route-A. The structure and formation of targeted Schiff bases (SBs) were confirmed by different spectroscopic techniques (1H NMR, 13C NMR and Mass). Finally, in vitro antimicrobial screening result revealed that the synthesised SBs derivatives may act as moderate antimicrobial agents.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135164696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Ahmed Messai, Mokhtar Saidi, Hocine Dandougui
This study aims to study a wild plant Herniaria fontanesii J. Gay which grows in Septentrional Sahara in El Oued Algeria. The evaluation of total phenolic and flavonoids content has been estimated in both aqueous and butanolic fractions of 80% methanolic extracts obtained from the plant's aerial part. Antioxidant activity was evaluated in vitro using scavenging assays of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and 2,2′-azino-bis (3- ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals, ferric reducing power FRAP and molybdenum reducing power methods. The extracts showed that the plant has a good antioxidant activity reaching to 1.525± 0.010 mg/ml for IC50 in DPPH assay and 0.011± 2.16610-5 mg/ml for IC50 in ABTS assay. A comparison has been done between these results and other results for the same plant harvested in Morocco, Tunisia and Laghouat, Algeria.
本研究旨在研究一种生长在阿尔及利亚西部撒哈拉沙漠地区的野生植物Herniaria fontanesii J. Gay。对从该植物地上部分提取的80%甲醇提取物的水溶液和丁醇组分进行了总酚和总黄酮含量的评价。采用体外清除1,1-二苯基-2-吡啶肼(DPPH)自由基和2,2 ' -氮基-双(3-乙基苯并噻唑-6-磺酸)(ABTS)自由基、铁还原力FRAP和钼还原力法评价其体外抗氧化活性。结果表明，该提取物具有较好的抗氧化活性，DPPH和ABTS测定的IC50分别为1.525±0.010 mg/ml和0.011±2.16610-5 mg/ml。将这些结果与在摩洛哥、突尼斯和阿尔及利亚的Laghouat收获的同一种植物的其他结果进行了比较。
{"title":"Contribution to the valorization of Herniaria fontanesii J. Gay (Caryophyllaceae) grown in Septentrional Sahara and its antioxidant activity","authors":"Mohamed Ahmed Messai, Mokhtar Saidi, Hocine Dandougui","doi":"10.25303/2709rjce053059","DOIUrl":"https://doi.org/10.25303/2709rjce053059","url":null,"abstract":"This study aims to study a wild plant Herniaria fontanesii J. Gay which grows in Septentrional Sahara in El Oued Algeria. The evaluation of total phenolic and flavonoids content has been estimated in both aqueous and butanolic fractions of 80% methanolic extracts obtained from the plant's aerial part. Antioxidant activity was evaluated in vitro using scavenging assays of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and 2,2′-azino-bis (3- ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals, ferric reducing power FRAP and molybdenum reducing power methods. The extracts showed that the plant has a good antioxidant activity reaching to 1.525± 0.010 mg/ml for IC50 in DPPH assay and 0.011± 2.16610-5 mg/ml for IC50 in ABTS assay. A comparison has been done between these results and other results for the same plant harvested in Morocco, Tunisia and Laghouat, Algeria.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135164848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The compound 2-[2-(4-arylamino)-4-phenylamino thiazol-5-oyl]naphthalene was synthesized and characterized by different physico-chemical techniques such as IR, electronic parameters, antioxidant studies etc. The geometrical and electronic characteristics of 2-[2-(4-arylamino)-4-phenylaminothiazol-5-oyl]napht halene were calculated theoretically using the Gaussian 09W software at the B3LYP/6-31G level of theory. The predicted geometrical characteristics are close to those published for 2-[2-(4-arylamino)-4-phenylaminothiazol-5-oyl]naphthalene with similar structures. Geometrical parameters are dependent on the atom's size, bonding nature and charge transfer according to optimization. The estimated MOs are helpful in determining the optimised compounds' collective electronic characteristics. Energy gap, on the other hand, is a measure of chemical reactivity, kinetic stability and polarizability.
{"title":"Synthesis, computational and anti-oxidant studies of 2-[2-(4-arylamino)-4-phenylaminothiazol-5-oyl]naphthalene","authors":"J. Jebalenet, J. Jenisha, Reji T.F. Abbs Fen","doi":"10.25303/2709rjce08016","DOIUrl":"https://doi.org/10.25303/2709rjce08016","url":null,"abstract":"The compound 2-[2-(4-arylamino)-4-phenylamino thiazol-5-oyl]naphthalene was synthesized and characterized by different physico-chemical techniques such as IR, electronic parameters, antioxidant studies etc. The geometrical and electronic characteristics of 2-[2-(4-arylamino)-4-phenylaminothiazol-5-oyl]napht halene were calculated theoretically using the Gaussian 09W software at the B3LYP/6-31G level of theory. The predicted geometrical characteristics are close to those published for 2-[2-(4-arylamino)-4-phenylaminothiazol-5-oyl]naphthalene with similar structures. Geometrical parameters are dependent on the atom's size, bonding nature and charge transfer according to optimization. The estimated MOs are helpful in determining the optimised compounds' collective electronic characteristics. Energy gap, on the other hand, is a measure of chemical reactivity, kinetic stability and polarizability.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135164840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A series of novel trifluoromethyl-thieno[2,3-b] pyridine-2-carboxamide 3a-h and Schiff’s base derivatives 5a-g was prepared starting from 6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carb onitrile 1. Compound 1 on reaction with bromoethyl acetate produced ester derivative 2 on reaction with different amines produced amide derivatives 3. Ester derivative 2 which on reaction with hydrazine hydrate gave hydrazide 4 derivative. Further this compound on reaction with different substituted aromatic aldehydes formed Schiff’s base derivatives 5. All the products 3a-h and 5a-f were screened against four human cancer cell lines such as HeLa -Cervical cancer (CCL-2), COLO 205-Colon cancer (CCL-222), HepG2-Liver cancer (HB-8065) and MCF7-Breast cancer (HTB-22). Promising compounds 3a and 3c have been identified with reference to standard control of 5-Fluorouracil.
{"title":"Novel trifluoromethyl-thieno[2,3-b]pyridine-2-carboxamide and Schiff’s base derivatives and their anticancer activity","authors":"Balakishan Vadla, Naveen Puram, Sailu Betala","doi":"10.25303/2709rjce069074","DOIUrl":"https://doi.org/10.25303/2709rjce069074","url":null,"abstract":"A series of novel trifluoromethyl-thieno[2,3-b] pyridine-2-carboxamide 3a-h and Schiff’s base derivatives 5a-g was prepared starting from 6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carb onitrile 1. Compound 1 on reaction with bromoethyl acetate produced ester derivative 2 on reaction with different amines produced amide derivatives 3. Ester derivative 2 which on reaction with hydrazine hydrate gave hydrazide 4 derivative. Further this compound on reaction with different substituted aromatic aldehydes formed Schiff’s base derivatives 5. All the products 3a-h and 5a-f were screened against four human cancer cell lines such as HeLa -Cervical cancer (CCL-2), COLO 205-Colon cancer (CCL-222), HepG2-Liver cancer (HB-8065) and MCF7-Breast cancer (HTB-22). Promising compounds 3a and 3c have been identified with reference to standard control of 5-Fluorouracil.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135164835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Green synthesis of nanoparticles via nanotechnology has many potential applications in various fields. The main aim of green synthesis is to decrease the use of toxic chemicals. Nanotechnology is considered as the revolution in the field of science and technology. It involves the manipulation of materials and synthesizes structures of different atoms and molecules on nano-scale having similar chemical composition to larger synthesized nanoparticles which had never been as easy as it has become with the “green-synthesis” methodologies. Using plants and micro-organisms such as bacteria, fungi have thus become biologically safe, cost-effective and environmental-friendly. In this review, we have discussed about green-synthesis and the different techniques that are involved for formation of nanoparticles and focused mainly on gold and silver nanoparticles including their sources and various anti-bacterial, anti-fungal, anti-viral, anti-cancerous, anti-inflammatory, anti-fibrotic properties.
{"title":"Green Synthesis of Nanoparticles from Natural Resources; Their Study and Applications","authors":"Porshia Sharma, Pragya Rathore, Richa Pathak, Ayushi Verma","doi":"10.25303/2709rjce1450154","DOIUrl":"https://doi.org/10.25303/2709rjce1450154","url":null,"abstract":"Green synthesis of nanoparticles via nanotechnology has many potential applications in various fields. The main aim of green synthesis is to decrease the use of toxic chemicals. Nanotechnology is considered as the revolution in the field of science and technology. It involves the manipulation of materials and synthesizes structures of different atoms and molecules on nano-scale having similar chemical composition to larger synthesized nanoparticles which had never been as easy as it has become with the “green-synthesis” methodologies. Using plants and micro-organisms such as bacteria, fungi have thus become biologically safe, cost-effective and environmental-friendly. In this review, we have discussed about green-synthesis and the different techniques that are involved for formation of nanoparticles and focused mainly on gold and silver nanoparticles including their sources and various anti-bacterial, anti-fungal, anti-viral, anti-cancerous, anti-inflammatory, anti-fibrotic properties.","PeriodicalId":21012,"journal":{"name":"Research Journal of Chemistry and Environment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135164836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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