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An efficient synthesis of new benzohydrazide and 1, 3-thiazine fused s-triazines as potential antimicrobial agents 新型苯并肼和1,3 -噻嗪融合s-三嗪的高效合成
Pub Date : 2018-04-15 DOI: 10.18231/2320-1924.2018.0006
G. Malik, T. Patel
As a part of our endeavor toward the synthesis of new heterocyclic bioactive agents, some new substituted 1,3,5 triazine derivatives with 4-nitrobenzohydrazide and 6-(4-methoxyphenyl)-4-phenyl-6H-1,3-thiazin-2-amine and substituted thiourea were reacted and evaluated for their in vitro antimicrobial activity against Gram positive and Gram negative strains using a micro dilution procedure. Synthesized compounds T1GE to T15GE showed to be effective with MIC (µg/mL), among them T5GE, T8GE, T9GE and T14GE showed excellent activity against a panel of microorganisms. The newly synthesized compounds were characterized using IR, 1H-NMR, 13C-NMR, MASS Analysis. Keywords: Cyanuric Chloride, 4-nitrobenzohydrazide, 6-(4-methoxyphenyl)-4-phenyl-6H-1, 3-thiazin-2-amine, Different thiourea derivatives and antimicrobial activity.
作为合成新的杂环生物活性药物的一部分,我们用微稀释法对一些新的取代1,3,5三嗪衍生物与4-硝基苯并肼、6-(4-甲氧基苯基)-4-苯基- 6h -1,3-噻嗪-2胺和取代硫脲进行了反应,并评价了它们对革兰氏阳性和革兰氏阴性菌株的体外抗菌活性。合成的化合物T1GE ~ T15GE对MIC有效(µg/mL),其中T5GE、T8GE、T9GE和T14GE对一组微生物具有良好的活性。新合成的化合物通过IR、1H-NMR、13C-NMR、MASS Analysis进行了表征。关键词:三聚氰胺,4-硝基苯并肼,6-(4-甲氧基苯基)-4-苯基- 6h - 1,3 -噻嗪-2-胺,不同硫脲衍生物及抗菌活性
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引用次数: 0
Impact of Rural Industrialization Against the Reproductive Health of Women Workers in the Industrial Sector in Sukabumi 农村工业化对苏卡umi工业部门女工生殖健康的影响
Pub Date : 2017-12-01 DOI: 10.3923/RJBSCI.2017.4.5
Martya Rahmaniarti, D. Susanna, T. Eryando, Dian Pratiwi
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引用次数: 0
Fungal Diseases of Olive Cuttings in the Rooting Stage in Jordan 约旦地区橄榄扦插生根期真菌病害的研究
Pub Date : 2012-08-01 DOI: 10.3923/rjbsci.2012.297.301
M. Al-Khatib
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引用次数: 3
Cutaneous and Gastrointestinal Helminth Parasites of the Fish Synodontis schall and Synodontis nigrita (Siluriformes: Mochokidae) from the Lower Ouémé Valley in South Benin 南贝宁下乌姆萨梅斯河谷小鳞滑膜鱼和黑滑膜鱼的皮肤和胃肠道寄生虫(siluriforma: Mochokidae)
Pub Date : 2012-08-01 DOI: 10.3923/RJBSCI.2012.320.326
E. Montchowui, J. Dougnon, F. D. Daga, Jedirfort Houessiono, P. Lalèyè, N. Sakiti
Since, approximately 2 decades, there has been a regression of fish captures in Benin and particularly in the Basin of Oueme river. A high parasitic infestation which would affect negatively the dynamics of the halieutic population, would be one of the probable causes of this regression. The present study aims to inventory helminth parasites in Synodontis schall and Synodontis nigrita from the lower Oueme valley in South Benin and to estimate their prevalence. A sample of 75 specimens of the 2 fish species was examined at the laboratory between September and October, 2011. The results revealed high parasitic prevalence in the two species: 82.14 and 78.72%, respectively. Six helminth genus were identified of which one digenean trematode (Clinostomum sp.), three nematodes (Cithariniella petterae, Procamallanus laeviconchus, Synodontisia thelastomoides) and two cestodes Stoeksia pujehuni and Lytocestus sp. Of the three parasites groups, nematodes are most abundant in both Mochokidae examined; they are 66.53 and 90.58% of parasites counted, respectively in S. schall and S. nigrita . Synodontisia thelastomoides has the highest prevalence: 46.43% in Synodontis schall and 42.55% in Synodontis nigrita.
大约20年来,贝宁,特别是Oueme河流域的渔获量有所下降。高度的寄生虫侵染会对海蜇种群的动态产生负面影响,这可能是这种退化的原因之一。本研究旨在调查贝宁南部Oueme河谷下游地区的小囊炎和黑囊炎寄生虫,并估计其流行率。2011年9月至10月期间,在实验室对这两种鱼类的75个样本进行了检查。结果表明,两种昆虫的寄生率分别为82.14%和78.72%。共鉴定出6种寄生虫属,其中线虫属1种(Clinostomum sp.),线虫属3种(Cithariniella petterae, proamallanus laeviconchus, sydontisia thelastomoides),线虫属2种(Stoeksia pujehuni和Lytocestus sp.)。在3种寄生虫类群中,线虫属在Mochokidae中数量最多;小棘球绦虫和黑棘球绦虫分别占总数的66.53%和90.58%。小滑膜炎患病率最高,为46.43%,黑滑膜炎为42.55%。
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引用次数: 9
Morphological and Physiological Characterization of Alternaria solani Isolated from Tomato in Jordan Valley 约旦河谷番茄褐变菌的形态和生理特性研究
Pub Date : 2012-08-01 DOI: 10.3923/RJBSCI.2012.316.319
Khalaf M. Alhussa
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引用次数: 15
Formulation of an Anti-bacterial and Anti-corrosion Paint 一种抗菌防腐蚀涂料的配方
Pub Date : 2012-08-01 DOI: 10.3923/RJBSCI.2012.302.306
S. A. Taheri, F. Taheri, Mohaddeseh Namjoo
{"title":"Formulation of an Anti-bacterial and Anti-corrosion Paint","authors":"S. A. Taheri, F. Taheri, Mohaddeseh Namjoo","doi":"10.3923/RJBSCI.2012.302.306","DOIUrl":"https://doi.org/10.3923/RJBSCI.2012.302.306","url":null,"abstract":"","PeriodicalId":21014,"journal":{"name":"Research journal of pharmaceutical, biological and chemical sciences","volume":"16 1","pages":"302-306"},"PeriodicalIF":0.0,"publicationDate":"2012-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76880905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Relationship Between Iron Status and Pulmonary and Extra Pulmonary Tuberculosis: A Case-control Study 评价铁状态与肺结核和肺外结核的关系:一项病例对照研究
Pub Date : 2012-08-01 DOI: 10.3923/RJBSCI.2012.312.315
M. Nezhady, N. Gharebaghi, N. Atarod, Ehsan Jelodari, N. Hoseinzade
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引用次数: 0
Effects of Organic-Chemical Fertilizer on the Growth and Yield of Rice (Chai Nat 1) 有机肥对水稻生长和产量的影响(柴纳1号)
Pub Date : 2012-07-01 DOI: 10.3923/RJBSCI.2012.265.269
Sopit Vetayasupo
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引用次数: 6
Photosynthetic and Antioxidant Responses of the Xero-Halophyte Zygophyllum album (L.) to Salt Stress 旱盐生刺槐对盐胁迫的光合和抗氧化反应
Pub Date : 2012-07-01 DOI: 10.3923/RJBSCI.2012.278.284
Fayçal Boughalleb, M. Denden, M. Neffati
{"title":"Photosynthetic and Antioxidant Responses of the Xero-Halophyte Zygophyllum album (L.) to Salt Stress","authors":"Fayçal Boughalleb, M. Denden, M. Neffati","doi":"10.3923/RJBSCI.2012.278.284","DOIUrl":"https://doi.org/10.3923/RJBSCI.2012.278.284","url":null,"abstract":"","PeriodicalId":21014,"journal":{"name":"Research journal of pharmaceutical, biological and chemical sciences","volume":"87 1","pages":"278-284"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84113769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytokine Release of Two Endodontic Biomaterials 两种牙髓生物材料的细胞因子释放
Pub Date : 2012-07-01 DOI: 10.3923/RJBSCI.2012.260.264
L. Marvasti, Bahareh Tabarsi, E. Zabihi, Amrollah Mostafazad, Azadeh Fazli, S. Asgary
{"title":"Cytokine Release of Two Endodontic Biomaterials","authors":"L. Marvasti, Bahareh Tabarsi, E. Zabihi, Amrollah Mostafazad, Azadeh Fazli, S. Asgary","doi":"10.3923/RJBSCI.2012.260.264","DOIUrl":"https://doi.org/10.3923/RJBSCI.2012.260.264","url":null,"abstract":"","PeriodicalId":21014,"journal":{"name":"Research journal of pharmaceutical, biological and chemical sciences","volume":"32 1","pages":"260-264"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75158040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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