Pub Date : 2022-11-12DOI: 10.52711/0975-4385.2022.00043
Bhavisha Patel, Anuraag Rai, H. Raut, Akshay Khandhar, Nirav Khunt
Improvement of Nanotechnology has been an obvious progression in the area of Science and Technology. The Nanotechnology strategy utilized in the plan of novel dose structure has given the Conventional measurement structure an extraordinary climb. Nanotechnology in drug field is frequently alluded to fuse of medication particles in nano size in a molecule size going from 1-100 nm which will help in expanding the remedial action.
{"title":"Synthesis of Zinc Nanoparticle by Using Peppermint Leaves and Evaluation of Zinc Nanoparticle by UV, SEM and XRDS","authors":"Bhavisha Patel, Anuraag Rai, H. Raut, Akshay Khandhar, Nirav Khunt","doi":"10.52711/0975-4385.2022.00043","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00043","url":null,"abstract":"Improvement of Nanotechnology has been an obvious progression in the area of Science and Technology. The Nanotechnology strategy utilized in the plan of novel dose structure has given the Conventional measurement structure an extraordinary climb. Nanotechnology in drug field is frequently alluded to fuse of medication particles in nano size in a molecule size going from 1-100 nm which will help in expanding the remedial action.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82203632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00032
Dipesh R Karnavat, Pratiksha S.Bhadane, Ritu M. Khairnar, Shweta S.Gavit
Shampoos are products that remove excess oil, dust on the skin and scalp. Many of the ingredients in shampoos are chemical and that is why they have been severely attacked due to the potential risk of side effects with their use. The main objective of this study was to eliminate the harmful synthetic ingredient in dandruff anti-dandruff and to replace it with safe natural ingredients. An effort has been made to integrate modern formulation technology into a formula based on natural ingredients. The herbal shampoo was prepared with Ritha fruit, Liquorice stolon's, Bengal gram seeds, Brahmi leaves, Green-gram seeds collected in an Ayurvedic store and remained as Banana roots, pomegranate seeds, leaves Hibiscus, Marigold flowers, and lemon fruit and all the ingredients are extracted and create a unique texture and stability tested with Dove shampoo on the market. Formulation 4 was found to be the best method based on the criteria for testing and stability studies. In a review of research data, the development of four anti-dandruff anti-dandruff anti-dandruff products containing all the positive properties of a suitable shampoo and was found to be safe, effective and economical compared to synthetic Dove anti dandruff shampoo, proved to be a stable improvement., an effective herbal anti- dandruff shampoo that may be commercially available instead of an existing synthetic shampoo is possible.
{"title":"Formulation and Evaluation of Herbal Antidandruff Shampoo","authors":"Dipesh R Karnavat, Pratiksha S.Bhadane, Ritu M. Khairnar, Shweta S.Gavit","doi":"10.52711/0975-4385.2022.00032","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00032","url":null,"abstract":"Shampoos are products that remove excess oil, dust on the skin and scalp. Many of the ingredients in shampoos are chemical and that is why they have been severely attacked due to the potential risk of side effects with their use. The main objective of this study was to eliminate the harmful synthetic ingredient in dandruff anti-dandruff and to replace it with safe natural ingredients. An effort has been made to integrate modern formulation technology into a formula based on natural ingredients. The herbal shampoo was prepared with Ritha fruit, Liquorice stolon's, Bengal gram seeds, Brahmi leaves, Green-gram seeds collected in an Ayurvedic store and remained as Banana roots, pomegranate seeds, leaves Hibiscus, Marigold flowers, and lemon fruit and all the ingredients are extracted and create a unique texture and stability tested with Dove shampoo on the market. Formulation 4 was found to be the best method based on the criteria for testing and stability studies. In a review of research data, the development of four anti-dandruff anti-dandruff anti-dandruff products containing all the positive properties of a suitable shampoo and was found to be safe, effective and economical compared to synthetic Dove anti dandruff shampoo, proved to be a stable improvement., an effective herbal anti- dandruff shampoo that may be commercially available instead of an existing synthetic shampoo is possible.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"2017 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75147587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00036
Bhupendra M. Mahale, Akshata M. Girase
The short review of this paper states that the patients those who have come across the severe pandemic COVID-19 are now suffering from the various types of fungal infection. In our study it gives the knowledge regarding what are the reason behind the fungal appearance in the patients, how does the fungal appeared, why only in the patients of COVID-19 it’signs and symptoms. The paper also gives the general infection about the treatment that has to be carried in such cases the therapy used in it.
{"title":"Study on covid-19 patients and the attacking fungus during post covid","authors":"Bhupendra M. Mahale, Akshata M. Girase","doi":"10.52711/0975-4385.2022.00036","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00036","url":null,"abstract":"The short review of this paper states that the patients those who have come across the severe pandemic COVID-19 are now suffering from the various types of fungal infection. In our study it gives the knowledge regarding what are the reason behind the fungal appearance in the patients, how does the fungal appeared, why only in the patients of COVID-19 it’signs and symptoms. The paper also gives the general infection about the treatment that has to be carried in such cases the therapy used in it.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"36 9-10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91498890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00035
Pankaj B. Satpute, Dattaprasad N. Vikhe
Guduchi is a Sanskrit word that meaning "protector of the body." It's also known as amrta or nectar, and it's incredibly beneficial for boosting the body's immune system and balancing the activities of its numerous organs. As a result, attempts have been made in the current research activity to give a comprehensive study on Guduchi Satva, with its authentication and validation carried out in a variety of ways. Tinospora cordifolia Genuine and market samples were examined for pharmacognostic characterization, phytochemical screening, and antibacterial testing during standardization. According to studies, the market sample was tainted and could not be used as a safe and effective medicine. This identification was utilized to create multiple markers for guduchi satva standardization. These features can also be employed as key identifiers in Ayurvedic pharmacopoeia. As a result, these indicators may be employed scientifically to detect adulteration and maintain medicine purity. In this study, a single Guduchi formulation, Guduchi Satva, is prepared using three different sizes (diameters) of Guduchi stems in three different batches in order to determine the ideal size of Guduchi stem that should be used to obtain the highest yield. Throughout the investigation, standard surgical protocols are followed.
{"title":"Pharmacognosy and Phytochemistry of Tinospora cordifolia","authors":"Pankaj B. Satpute, Dattaprasad N. Vikhe","doi":"10.52711/0975-4385.2022.00035","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00035","url":null,"abstract":"Guduchi is a Sanskrit word that meaning \"protector of the body.\" It's also known as amrta or nectar, and it's incredibly beneficial for boosting the body's immune system and balancing the activities of its numerous organs. As a result, attempts have been made in the current research activity to give a comprehensive study on Guduchi Satva, with its authentication and validation carried out in a variety of ways. Tinospora cordifolia Genuine and market samples were examined for pharmacognostic characterization, phytochemical screening, and antibacterial testing during standardization. According to studies, the market sample was tainted and could not be used as a safe and effective medicine. This identification was utilized to create multiple markers for guduchi satva standardization. These features can also be employed as key identifiers in Ayurvedic pharmacopoeia. As a result, these indicators may be employed scientifically to detect adulteration and maintain medicine purity. In this study, a single Guduchi formulation, Guduchi Satva, is prepared using three different sizes (diameters) of Guduchi stems in three different batches in order to determine the ideal size of Guduchi stem that should be used to obtain the highest yield. Throughout the investigation, standard surgical protocols are followed.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81916944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00031
Keshav Chandravanshi, M. Sahu, Raju Sahu, Neelima Sahu, S. Lanjhiyana, A. Chandy
In current scenario pharmaceutical dosage forms contain many additives besides the active ingredients to assist manufacturing and to obtain the desired effect to the pharmaceutical active ingredientsPlant Mucilages are pharmaceutically important polysaccharide with wide range of applications such as thickening, binding, disintegrating, suspending, emulsifying, stabilizing and gelling agents. Naturally availablemucilages are preferred to synthetic materials due to their non toxicity, low cost, emollient and non-irritating nature. The synthetic polymers have certain disadvantages such as high cost, toxicity, environmental pollution during synthesis, non-renewable sources, side effects, less patient compliance, etc. mucilages are potent candidate to be used in various pharmaceutical formulations as a potential candidate for novel drug delivery system (NDDS). In this review, we describe the developments in natural gums, mucilages and Pectins for use in the pharmaceutical sciences.
{"title":"Isolation of Mucilage from Herbal plants and its Evaluation as a Pharmaceutical Excipients","authors":"Keshav Chandravanshi, M. Sahu, Raju Sahu, Neelima Sahu, S. Lanjhiyana, A. Chandy","doi":"10.52711/0975-4385.2022.00031","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00031","url":null,"abstract":"In current scenario pharmaceutical dosage forms contain many additives besides the active ingredients to assist manufacturing and to obtain the desired effect to the pharmaceutical active ingredientsPlant Mucilages are pharmaceutically important polysaccharide with wide range of applications such as thickening, binding, disintegrating, suspending, emulsifying, stabilizing and gelling agents. Naturally availablemucilages are preferred to synthetic materials due to their non toxicity, low cost, emollient and non-irritating nature. The synthetic polymers have certain disadvantages such as high cost, toxicity, environmental pollution during synthesis, non-renewable sources, side effects, less patient compliance, etc. mucilages are potent candidate to be used in various pharmaceutical formulations as a potential candidate for novel drug delivery system (NDDS). In this review, we describe the developments in natural gums, mucilages and Pectins for use in the pharmaceutical sciences.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73117073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00027
U. Khasanah, Oktavia Rahayu Adiningsih, Ernila Dewi Anggraeni, Firda Uswatul Uliyah, Annisa Intan Ramadhani, Aloysia Aprilla Dewi Saraswati, Gita Kurnia Ardiani
The exploration of plants as a source of medicinal raw materials has increased since the last few decades, both for infectious, degenerative, and malignant diseases. One of the medicinal plants currently being developed for cancer is Syzygium cumini. Powder of Syzygium cumini was extracted using 96% ethanol. Each extract was determined for its phytochemical screening, total phenolic content, and cytotoxic activity against 4T1 cell culture. Total phenolic content was determined by the Folin-Ciocalteu method and UV-VIS spectrophotometer. Cytotoxic test was performed using MTT assay with parameter IC50 value. The results showed that the total phenolic content of 96% ethanol extract of Syzygium cumini seed, leaf, and pulp was 503.01±9.21; 329.60± 20.37; 24.09 ±0.57mg GAE/g. Syzygium cumini seed, leaf, and pulp extracts exhibited cytotoxic activity with IC50 613.92±40.49; 660.18±15.02; 732.68±69.41µg/ml. Syzygium cumini seed extract has the highest total phenolic content and the most potent cytotoxic activity.
{"title":"Phytochemical screening, Total Phenolic content and Cytotoxic Activity of Seed, Leaves, and Pulp from Syzygium cumini against Breast Cancer Cell Culture 4T1","authors":"U. Khasanah, Oktavia Rahayu Adiningsih, Ernila Dewi Anggraeni, Firda Uswatul Uliyah, Annisa Intan Ramadhani, Aloysia Aprilla Dewi Saraswati, Gita Kurnia Ardiani","doi":"10.52711/0975-4385.2022.00027","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00027","url":null,"abstract":"The exploration of plants as a source of medicinal raw materials has increased since the last few decades, both for infectious, degenerative, and malignant diseases. One of the medicinal plants currently being developed for cancer is Syzygium cumini. Powder of Syzygium cumini was extracted using 96% ethanol. Each extract was determined for its phytochemical screening, total phenolic content, and cytotoxic activity against 4T1 cell culture. Total phenolic content was determined by the Folin-Ciocalteu method and UV-VIS spectrophotometer. Cytotoxic test was performed using MTT assay with parameter IC50 value. The results showed that the total phenolic content of 96% ethanol extract of Syzygium cumini seed, leaf, and pulp was 503.01±9.21; 329.60± 20.37; 24.09 ±0.57mg GAE/g. Syzygium cumini seed, leaf, and pulp extracts exhibited cytotoxic activity with IC50 613.92±40.49; 660.18±15.02; 732.68±69.41µg/ml. Syzygium cumini seed extract has the highest total phenolic content and the most potent cytotoxic activity.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80164019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00029
Nishant Nandkhile, Sachin Vanpure, Prathmesh Khetmalis, R. Bhondwe
The plants are enormous source of medicinally important ingredients. The separation of active plants compounds leads to discovery of many drugs derived directly from plants. In the current study, The HPLC analysis is carried for the methanolic extracts of gives different peaks at 254 nm, it may be alcoholic compound. The FTIR spectrum confirmed the presence of alcohol, alkanes, carboxylic acid, aromatics, esters and ethers in methanolic extract of Sonneratia apetala. UV-Visible profile showed different peaks ranging from 200-800 nm with different absorption respectively. In silico study, especially physicochemical properties, lipophilicity, water solubility, pharmacokinetics, drug likeness and medicinal chemistry performed by using the Swiss ADME online tool.
{"title":"Spectroscopic Analysis and ADME Studies of Phytochemicals in Methanolic Leaves Extract of Sonneratia apetala Buch.-Ham","authors":"Nishant Nandkhile, Sachin Vanpure, Prathmesh Khetmalis, R. Bhondwe","doi":"10.52711/0975-4385.2022.00029","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00029","url":null,"abstract":"The plants are enormous source of medicinally important ingredients. The separation of active plants compounds leads to discovery of many drugs derived directly from plants. In the current study, The HPLC analysis is carried for the methanolic extracts of gives different peaks at 254 nm, it may be alcoholic compound. The FTIR spectrum confirmed the presence of alcohol, alkanes, carboxylic acid, aromatics, esters and ethers in methanolic extract of Sonneratia apetala. UV-Visible profile showed different peaks ranging from 200-800 nm with different absorption respectively. In silico study, especially physicochemical properties, lipophilicity, water solubility, pharmacokinetics, drug likeness and medicinal chemistry performed by using the Swiss ADME online tool.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"337 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76401585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00030
M. V., S. K., P. S., A. K., Niyathi V
This study aims to analyze the antioxidant, antidiabetic, and antibacterial properties of the leaves of the plant Orthosiphon diffusus, which were investigated in vitro. Leaves of the plant were dried and converted into powdered form. The presence of phytochemicals in the leaves of Orthosiphon diffusus were analysed for solvents like water, ethanol, acetone and petroleum ether. The antioxidant activity of the leaves of Orthosiphon diffusus was identified using assays for scavenging the 1,1-diphenyl-2-picrylhydrazyl hydrate, ferric reducing antioxidants, nitric oxide and hydrogen peroxide radicals. The antidiabetic property was estimated with alpha-amylase and alpha-glucosidase assays. Leaf extract was tested against three bacterial species namely Bacillus subtilis, Escherichia coli and Staphylococcus aureus by well diffusion method. Maximum number of phytochemicals were present in water extract which was then used for further studies. Highest scavenging activity was found to be 76%, 89%, 88% and 81% at 50µg/ml for all the antioxidant assays. Highest inhibition of 90.26% and 90.5% was observed at 50µg/ml for alpha amylase and alpha glucosidase assays respectively. Highest zone of inhibition of 1.4cm was observed in S.aureus at 100µg/ml concentration. Leaves of Orthosiphon diffusus has excellent antioxidant and antidiabetic properties and it was really effective against bacteria.
{"title":"In vitro Antioxidant, Antidiabetic and Antibacterial Activities of Orthosiphon diffusus","authors":"M. V., S. K., P. S., A. K., Niyathi V","doi":"10.52711/0975-4385.2022.00030","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00030","url":null,"abstract":"This study aims to analyze the antioxidant, antidiabetic, and antibacterial properties of the leaves of the plant Orthosiphon diffusus, which were investigated in vitro. Leaves of the plant were dried and converted into powdered form. The presence of phytochemicals in the leaves of Orthosiphon diffusus were analysed for solvents like water, ethanol, acetone and petroleum ether. The antioxidant activity of the leaves of Orthosiphon diffusus was identified using assays for scavenging the 1,1-diphenyl-2-picrylhydrazyl hydrate, ferric reducing antioxidants, nitric oxide and hydrogen peroxide radicals. The antidiabetic property was estimated with alpha-amylase and alpha-glucosidase assays. Leaf extract was tested against three bacterial species namely Bacillus subtilis, Escherichia coli and Staphylococcus aureus by well diffusion method. Maximum number of phytochemicals were present in water extract which was then used for further studies. Highest scavenging activity was found to be 76%, 89%, 88% and 81% at 50µg/ml for all the antioxidant assays. Highest inhibition of 90.26% and 90.5% was observed at 50µg/ml for alpha amylase and alpha glucosidase assays respectively. Highest zone of inhibition of 1.4cm was observed in S.aureus at 100µg/ml concentration. Leaves of Orthosiphon diffusus has excellent antioxidant and antidiabetic properties and it was really effective against bacteria.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73310668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00033
Anuraag Rai, B. Chauhan, Devshree N. Parmar
Natural herb oils of Origanum vulgare, Melaleuca alternifolia and Anethum graveolans were used to formulate a o/w emulsion type cream. Firstly, the authenticity of the cream was determined using reference standards such as thymol, carvone and cineole and then different phytochemical tests were carried out using standard procedures. The formulation of the cream was designed using Minitab software. The prepared cream was then subjected to antifungal assay. The synergistic effect of three herb oils were also studied and discussed.
{"title":"Testing of Antifungal Activity of Herbal Cream Made with Natural Herbal Oils (Origanum vulgare, Melaleuca alternifolia, Anethum graveolans)","authors":"Anuraag Rai, B. Chauhan, Devshree N. Parmar","doi":"10.52711/0975-4385.2022.00033","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00033","url":null,"abstract":"Natural herb oils of Origanum vulgare, Melaleuca alternifolia and Anethum graveolans were used to formulate a o/w emulsion type cream. Firstly, the authenticity of the cream was determined using reference standards such as thymol, carvone and cineole and then different phytochemical tests were carried out using standard procedures. The formulation of the cream was designed using Minitab software. The prepared cream was then subjected to antifungal assay. The synergistic effect of three herb oils were also studied and discussed.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78371777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-16DOI: 10.52711/0975-4385.2022.00028
C. R, P. R, Vandana B., Babitha R., T. S., S. B, Deepika G., M. Babu
Urolithiasis is a common disease, affecting a large number of people worldwide, affecting all the age groups from youngsters to old people. Urolithiasis is one of the most severe urologic disorders which are most prevalent in developed and developing countries. Lagerstroemia speciosa, belongs to the group of Lythraceae family, commonly called as crape myrtle is a medicinal plant that has traditionally been used as an antidiabetic, lowering blood glucose levels in the body. Banaba is the common name of Lagerstroemia speciosa. The current study was investigated for the in vitro antiurolithiatic potential of Langerstromia specoisa leaf extract (LSEE) against calcium oxalate (CaOx) urolithiasis. The mechanism of stone formation involves supersaturation, crystal nucleation, precipitation, crystal growth and aggregation of crystals. The CaOx crystal was characterized by FT-IR analysis. LSEE significantly inhibited the stone formation, nucleation, growth and aggregation of CaOx crystals. FT-IR characterization was used for analyzing the formation of calcium oxalate crystals, which will be used in growth and aggregation assays. LSEE has significant antiurolithiatic activity in vitro against CaOx urolithiasis, which could be attributed to its flavonoids, polyphenolic content, saponins and tannins.
{"title":"Evaluation of in vitro Antiurolithiatic Potential of Ethanolic Leaf Extract of Langerstromia specoisa","authors":"C. R, P. R, Vandana B., Babitha R., T. S., S. B, Deepika G., M. Babu","doi":"10.52711/0975-4385.2022.00028","DOIUrl":"https://doi.org/10.52711/0975-4385.2022.00028","url":null,"abstract":"Urolithiasis is a common disease, affecting a large number of people worldwide, affecting all the age groups from youngsters to old people. Urolithiasis is one of the most severe urologic disorders which are most prevalent in developed and developing countries. Lagerstroemia speciosa, belongs to the group of Lythraceae family, commonly called as crape myrtle is a medicinal plant that has traditionally been used as an antidiabetic, lowering blood glucose levels in the body. Banaba is the common name of Lagerstroemia speciosa. The current study was investigated for the in vitro antiurolithiatic potential of Langerstromia specoisa leaf extract (LSEE) against calcium oxalate (CaOx) urolithiasis. The mechanism of stone formation involves supersaturation, crystal nucleation, precipitation, crystal growth and aggregation of crystals. The CaOx crystal was characterized by FT-IR analysis. LSEE significantly inhibited the stone formation, nucleation, growth and aggregation of CaOx crystals. FT-IR characterization was used for analyzing the formation of calcium oxalate crystals, which will be used in growth and aggregation assays. LSEE has significant antiurolithiatic activity in vitro against CaOx urolithiasis, which could be attributed to its flavonoids, polyphenolic content, saponins and tannins.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89416404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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