Background: 65% of the causes of infertility are related to female factors. Receptive endometrium is essential for a successful pregnancy. In ART cycles, receptivity is not achieved optimally. Main body: Uterine receptivity is the ability of the uterus to accept a competent blastocyst. The factors affecting endometrial receptivity include: hormonal, genetic and immunological factors. During the receptive phase, different changes occur in endometrium (Cytoskeletal, biochemical and genetic). This review article discusses the interventions that can improve the uterine receptivity in ART cycles. Conclusion: PRP has growth factor and anti-inflammatory properties. It is safe and it has positive effects on endometrial receptivity. Endometrial scratching may be associated with the secretion of growth factors and cytokines involved in the wound healing process and may also contribute to enhancing the embryo implantation. Acupuncture is effective as a complimentary medicine and should be used along with routine medical approaches. Medications like aspirin, growth hormone and heparin that are used in ART cycles improve the receptivity. Use of stem cells in human is limited and although they have positive effects on animals, they have a long way to be safe enough to be used for human. Nutritional supplements like Carnitines, vitamin E and melatonin seems to be safe and effective in endometrial receptivity. In FET cycles, developmental synchrony between the embryo and uterus is maintained. Endometrial receptivity assay (ERA) was introduced as an accurate molecular tool to determine the endometrial receptivity status.
{"title":"Endometrial Receptivity In Art Cycles: A Review On Different Aspects Of Improvement","authors":"Bahare Rafiee, S. Bahmanpour","doi":"10.31838/SRP.2021.3.10","DOIUrl":"https://doi.org/10.31838/SRP.2021.3.10","url":null,"abstract":"Background: 65% of the causes of infertility are related to female factors. Receptive endometrium is essential for a successful pregnancy. In ART cycles, receptivity is not achieved optimally. Main body: Uterine receptivity is the ability of the uterus to accept a competent blastocyst. The factors affecting endometrial receptivity include: hormonal, genetic and immunological factors. During the receptive phase, different changes occur in endometrium (Cytoskeletal, biochemical and genetic). This review article discusses the interventions that can improve the uterine receptivity in ART cycles. Conclusion: PRP has growth factor and anti-inflammatory properties. It is safe and it has positive effects on endometrial receptivity. Endometrial scratching may be associated with the secretion of growth factors and cytokines involved in the wound healing process and may also contribute to enhancing the embryo implantation. Acupuncture is effective as a complimentary medicine and should be used along with routine medical approaches. Medications like aspirin, growth hormone and heparin that are used in ART cycles improve the receptivity. Use of stem cells in human is limited and although they have positive effects on animals, they have a long way to be safe enough to be used for human. Nutritional supplements like Carnitines, vitamin E and melatonin seems to be safe and effective in endometrial receptivity. In FET cycles, developmental synchrony between the embryo and uterus is maintained. Endometrial receptivity assay (ERA) was introduced as an accurate molecular tool to determine the endometrial receptivity status.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75755258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Othman, Muhammad Safuan Yusoff, Mohd Kamal Mohd Shah, Romzi Ationg, Mohd. Yakin
Malaysia is one of the countries that has become a choice of destination for international students to further their studies. Elements such as recognized international higher learning institution system, the intensive effort of student exchange programme, a calibre teaching team, contemporary and quality courses, an international consolidation with some other best learning institutions in the world together with the connection of regional cooperation are among the collected criteria to portray the ability of Malaysia in attracting more international students. Therefore, the objective of this research is to emphasise the factors that differentiate the first-year experience on self-assimilation as well as academic achievement among international students. The qualitative sampling method involved forty international students who participated voluntarily and data collection was conducted through an in-depth interview technique. The result has generated an understanding on international students self-reflection through the nature of their excitement, needs and hopes. Among the factors that were identified were (i) education system in Malaysian Public Universities is seen as a prestigious study destination, (ii) education system Malaysian Public Universities are more comprehensive and versatile, (iii) the learning programmes in Malaysian Universities learning are flexible and dynamic, (iv) the development of the programmes are contemporary and market driven (v) the added value on the benefits using English as a learning and teaching medium in Malaysian Public Universities. Therefore, in examining the quality level of education, it is vital to consider the learning satisfaction among international students in order to have a continuum on the health enhancement impact towards self-assimilation in their academic achievement. The findings are valuable and are useful in showing the significant relevance to the international human resource management Malaysian Public Universities which are dependent on international students at high proportions and applicable in formulating various national higher education policies.
{"title":"The Health Enhancement Impact Of Self Assimilation In Academic Achievement Amongst International Students In Malaysian Public Universities","authors":"I. Othman, Muhammad Safuan Yusoff, Mohd Kamal Mohd Shah, Romzi Ationg, Mohd. Yakin","doi":"10.31838/SRP.2021.3.79","DOIUrl":"https://doi.org/10.31838/SRP.2021.3.79","url":null,"abstract":"Malaysia is one of the countries that has become a choice of destination for international students to further their studies. Elements such as recognized international higher learning institution system, the intensive effort of student exchange programme, a calibre teaching team, contemporary and quality courses, an international consolidation with some other best learning institutions in the world together with the connection of regional cooperation are among the collected criteria to portray the ability of Malaysia in attracting more international students. Therefore, the objective of this research is to emphasise the factors that differentiate the first-year experience on self-assimilation as well as academic achievement among international students. The qualitative sampling method involved forty international students who participated voluntarily and data collection was conducted through an in-depth interview technique. The result has generated an understanding on international students self-reflection through the nature of their excitement, needs and hopes. Among the factors that were identified were (i) education system in Malaysian Public Universities is seen as a prestigious study destination, (ii) education system Malaysian Public Universities are more comprehensive and versatile, (iii) the learning programmes in Malaysian Universities learning are flexible and dynamic, (iv) the development of the programmes are contemporary and market driven (v) the added value on the benefits using English as a learning and teaching medium in Malaysian Public Universities. Therefore, in examining the quality level of education, it is vital to consider the learning satisfaction among international students in order to have a continuum on the health enhancement impact towards self-assimilation in their academic achievement. The findings are valuable and are useful in showing the significant relevance to the international human resource management Malaysian Public Universities which are dependent on international students at high proportions and applicable in formulating various national higher education policies.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91156068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamoud Abo Elenin Khattab, Youssef Mousa, Ragaa A Matta, Hend Mohamed Mounes, Ahmed Hamdy
Hepatocellular carcinoma (HCC) is an important clinical problem, as it is the second major cause of cancer deaths worldwide and one of the most common causes of cancer-related mortality in the U.S.
{"title":"Inflammatory Cytokines as a Predictor Markers for Hepatocellular Carcinoma","authors":"Mohamoud Abo Elenin Khattab, Youssef Mousa, Ragaa A Matta, Hend Mohamed Mounes, Ahmed Hamdy","doi":"10.31838/SRP.2021.3.121","DOIUrl":"https://doi.org/10.31838/SRP.2021.3.121","url":null,"abstract":"Hepatocellular carcinoma (HCC) is an important clinical problem, as it is the second major cause of cancer deaths worldwide and one of the most common causes of cancer-related mortality in the U.S.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84527230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heeral Mahlawat, Mds, Ashith M.V, Amoli Singh, Bds, K. Mustafa, K. Varshini
Oxygen has a vital role in regulating the normal body metabolism and is essential for all tissues. It enhances the vascularity of cells and increases their multiplication there by contributing significantly in wound healing. It is known to enhance the oxygenation of tissues along with having anti-bacterial and anti-inflammatory effects. Oxygen can also intensify the mechanisms involving tissue repair. HBOT (Hyperbaric oxygen therapy) is defined as a treatment modality where the patient is given 100% oxygen in a hyperbaric chamber through intermittent inhalation at a pressure higher than 1 absolute atmosphere for a specified period. The mechanism of action of HBOT is basically by increasing the amount of dissolved oxygen in the body drastically. This causes the oxygen levels in the plasma to increase and leads to better oxygen delivery. The growth of new blood vessels are encouraged and tissue homeostasis is restored. The function of white blood cells are enhanced along with the overall anti-bacterial effect. The aim of writing of this article is to clinically analyse the use of hyperbaric oxygen therapy during a complication post orthognathic surgery with a case discussion.
{"title":"Hyperbaric Oxygen Therapy : A Treatment Modality For Avascular Necrosis Of Maxilla- A Clinical Review.","authors":"Heeral Mahlawat, Mds, Ashith M.V, Amoli Singh, Bds, K. Mustafa, K. Varshini","doi":"10.31838/SRP.2021.3.78","DOIUrl":"https://doi.org/10.31838/SRP.2021.3.78","url":null,"abstract":"Oxygen has a vital role in regulating the normal body metabolism and is essential for all tissues. It enhances the vascularity of cells and increases their multiplication there by contributing significantly in wound healing. It is known to enhance the oxygenation of tissues along with having anti-bacterial and anti-inflammatory effects. Oxygen can also intensify the mechanisms involving tissue repair. HBOT (Hyperbaric oxygen therapy) is defined as a treatment modality where the patient is given 100% oxygen in a hyperbaric chamber through intermittent inhalation at a pressure higher than 1 absolute atmosphere for a specified period. The mechanism of action of HBOT is basically by increasing the amount of dissolved oxygen in the body drastically. This causes the oxygen levels in the plasma to increase and leads to better oxygen delivery. The growth of new blood vessels are encouraged and tissue homeostasis is restored. The function of white blood cells are enhanced along with the overall anti-bacterial effect. The aim of writing of this article is to clinically analyse the use of hyperbaric oxygen therapy during a complication post orthognathic surgery with a case discussion.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73490737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Nader Shalaby, Mona Mostafa Abdo Sakoury, Sherin Hussien, W. Gaber, Mohamed, Heba Fathy Heikal, Mentallah Ahmed Rabei, Mohamed Selim Mohamed Ahmed
Hormones regulate vital functions within the body in a balanced manner and within limited physiological limits. Excessive secretion of the hormone or deficiency leads to complications that hinder the vital processes carried out by the body. This study aimed to Understand the effect of using a suggested sports diet on increasing thyroid secretion and its effect on obesity. METHODS: The researchers used the experimental method due to its suitability to the nature of the research by designing two groups, one of which is an experimental group and the other is a control group using previous and post measurements. The research community included the university students in the academic year 2019/2020, whose number was (60) female students. The basic research sample was chosen by the intentional method (40) students and they were divided equally into two groups, the experimental group consisting of (20) students and the control group consisting of (20) students and an exploratory sample of (20) students from outside the basic sample and from the research community to ensure the scientific treatment of the tests Physical and pathological under study. RESULTS: the hypotheses between the pre-and post-measurements of the control group in the physical variables are statistically significant differences, as the calculated Z Value was higher than its tabular value at the level of 0.05, and this indicates the improvement of the control group in the physical variables under investigation. The researchers attribute this improvement to the control group to the presence of the researcher in the tests as well as to correct the form of performance and fix errors that appear first-hand, which had an impact on the mastery of the control group sample of the physical variables under discussion. Conclusions: The nutritional program has a positive effect on improving the activity of the thyroid gland and the secretion of its hormones in the body. The exercise program has a positive effect on some elements of physical fitness (muscle strength - flexibility). The sports program using Swiss balls has a positive effect on some elements of physical fitness (muscle strength - flexibility). The proposed sports and diet program together are stronger than alone to improve thyroid gland activity and secretion of its hormones. The proposed sports and nutritional program have a positive effect in reducing the level of moderate obesity on healthy people.
{"title":"The Effect of Using a Suggested Sport’s Diet on Increased Thyroid Secretion and Its Effect on Obesity -","authors":"Mohammed Nader Shalaby, Mona Mostafa Abdo Sakoury, Sherin Hussien, W. Gaber, Mohamed, Heba Fathy Heikal, Mentallah Ahmed Rabei, Mohamed Selim Mohamed Ahmed","doi":"10.31838/SRP.2021.1.115","DOIUrl":"https://doi.org/10.31838/SRP.2021.1.115","url":null,"abstract":"Hormones regulate vital functions within the body in a balanced manner and within limited physiological limits. Excessive secretion of the hormone or deficiency leads to complications that hinder the vital processes carried out by the body. This study aimed to Understand the effect of using a suggested sports diet on increasing thyroid secretion and its effect on obesity. METHODS: The researchers used the experimental method due to its suitability to the nature of the research by designing two groups, one of which is an experimental group and the other is a control group using previous and post measurements. The research community included the university students in the academic year 2019/2020, whose number was (60) female students. The basic research sample was chosen by the intentional method (40) students and they were divided equally into two groups, the experimental group consisting of (20) students and the control group consisting of (20) students and an exploratory sample of (20) students from outside the basic sample and from the research community to ensure the scientific treatment of the tests Physical and pathological under study. RESULTS: the hypotheses between the pre-and post-measurements of the control group in the physical variables are statistically significant differences, as the calculated Z Value was higher than its tabular value at the level of 0.05, and this indicates the improvement of the control group in the physical variables under investigation. The researchers attribute this improvement to the control group to the presence of the researcher in the tests as well as to correct the form of performance and fix errors that appear first-hand, which had an impact on the mastery of the control group sample of the physical variables under discussion. Conclusions: The nutritional program has a positive effect on improving the activity of the thyroid gland and the secretion of its hormones in the body. The exercise program has a positive effect on some elements of physical fitness (muscle strength - flexibility). The sports program using Swiss balls has a positive effect on some elements of physical fitness (muscle strength - flexibility). The proposed sports and diet program together are stronger than alone to improve thyroid gland activity and secretion of its hormones. The proposed sports and nutritional program have a positive effect in reducing the level of moderate obesity on healthy people.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90295200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This paper reveals the prevention of malnutrition and the reduction of stunting through the use of nutrition-based zakat by BAZNAS and Rumah Zakat in Indonesia. The philanthropy displayed by the two zakat institutions is different from the distribution of zakat in general. The research method applied is qualitative research. While the approach uses a conceptual approach and a textual-contextual approach. Data obtained from literature review and research results sourced from Google Scholar, Science Direct, Tandfonline, Sagepub and other reputable article sources. Based on conceptual and context analysis, this paper concludes that decreasing malnutrition such as malnutrition, malnutrition, wasting and stunting, as well as increased malnutrition such as obesity is a form of unequal, unfair and unintegrated food distribution. The abundant potential of zakat on food, and the contextual use of zakat carried out by BAZNAS and Rumah Zakat on many problematic nutrition targets, have had a micro positive impact on improving nutrition and alleviating stunting, both at the preventive and post-stunting stages. The nutrition-based zakat distribution model is the beginning of the birth of the nutritional zakat concept in the field of zakat.
{"title":"Contextualization of the Use of Zakat in Reducing Stunting: Evidence from Indonesia","authors":"Ahmad Dakhoir, I. Pelu, Dian Ferricha","doi":"10.31838/SRP.2021.4.35","DOIUrl":"https://doi.org/10.31838/SRP.2021.4.35","url":null,"abstract":"This paper reveals the prevention of malnutrition and the reduction of stunting through the use of nutrition-based zakat by BAZNAS and Rumah Zakat in Indonesia. The philanthropy displayed by the two zakat institutions is different from the distribution of zakat in general. The research method applied is qualitative research. While the approach uses a conceptual approach and a textual-contextual approach. Data obtained from literature review and research results sourced from Google Scholar, Science Direct, Tandfonline, Sagepub and other reputable article sources. Based on conceptual and context analysis, this paper concludes that decreasing malnutrition such as malnutrition, malnutrition, wasting and stunting, as well as increased malnutrition such as obesity is a form of unequal, unfair and unintegrated food distribution. The abundant potential of zakat on food, and the contextual use of zakat carried out by BAZNAS and Rumah Zakat on many problematic nutrition targets, have had a micro positive impact on improving nutrition and alleviating stunting, both at the preventive and post-stunting stages. The nutrition-based zakat distribution model is the beginning of the birth of the nutritional zakat concept in the field of zakat.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85520166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of present study is to explore knowledge, attitude and usage of family planning methods among married women in reproductive age in Mosul City. Subjects and Methods A descriptive cross-sectional study design was adopted to accomplish the aim of the current study. Data was collected from a convenient sample of 300 married women at child bearing age who visiting a maternity and child teaching hospital in Mosul City during a period of three months. Direct interview by using reformed standardized questionnaire form was used for data collection. Results Out of 300 participants 69.3% % heard about family planning but only Less than half (48.7%) give a correct concept of family planning and 28.7% have no idea . The prevalence of current contraceptive usage among participates was 61.3%. Traditional methods were rated as the most common contraceptive methods formerly used by 67.3% of the sample fallowed oral contraceptive pills by 31%. Fear from side effect was the main cause that prohibiting women to use contraceptives as ranked by 42%. Women in this study had a favorable attitude towards family planning. Conclusion and recommendations Married women in reproductive age in Mosul City had incomplete and inconsistent information about family planning. Although, contraceptive usage prevalence was within worldwide range but traditional methods were the most commonly used methods. Well-organized strategies should be adopted to promote family planning programs by depending on practical health education programs.
{"title":"Family Planning Methods Knowledge, Attitude And Usage Among Married Women In Reproductive Age In Mosul City.","authors":"N. H. Saied","doi":"10.31838/SRP.2021.1.125","DOIUrl":"https://doi.org/10.31838/SRP.2021.1.125","url":null,"abstract":"The aim of present study is to explore knowledge, attitude and usage of family planning methods among married women in reproductive age in Mosul City. Subjects and Methods A descriptive cross-sectional study design was adopted to accomplish the aim of the current study. Data was collected from a convenient sample of 300 married women at child bearing age who visiting a maternity and child teaching hospital in Mosul City during a period of three months. Direct interview by using reformed standardized questionnaire form was used for data collection. Results Out of 300 participants 69.3% % heard about family planning but only Less than half (48.7%) give a correct concept of family planning and 28.7% have no idea . The prevalence of current contraceptive usage among participates was 61.3%. Traditional methods were rated as the most common contraceptive methods formerly used by 67.3% of the sample fallowed oral contraceptive pills by 31%. Fear from side effect was the main cause that prohibiting women to use contraceptives as ranked by 42%. Women in this study had a favorable attitude towards family planning. Conclusion and recommendations Married women in reproductive age in Mosul City had incomplete and inconsistent information about family planning. Although, contraceptive usage prevalence was within worldwide range but traditional methods were the most commonly used methods. Well-organized strategies should be adopted to promote family planning programs by depending on practical health education programs.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84712197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helicobacter pylori (H. pylori) is a gram negative bacteria whose infection is highly prevalent among the human population and leads to gastrointestinal tract related diseases (gastric and duodenal ulcers, mucosa associated tissue lymphoma and gastric adenocarcinoma). Most people with H. pylori infection will never have any signs or symptoms. While this bacterium infects 50% of the world’s population, in Africa its prevalence reach as high as 80% as the infection is acquired during childhood. H. pylori eradication treatment is becoming more challenging due to increasing antimicrobial resistance. Treatment regimens are expected to overcome the increasing prevalence of resistant strains of H. pylori and achieve a >90% eradication rate. Although treatment regimens provide acceptable H. pylori eradication rates, the regimens used should contribute to future resistance of H. pylori to antimicrobials and other therapies.
幽门螺杆菌(Helicobacter pylori, H. pylori)是一种革兰氏阴性菌，其感染在人群中非常普遍，可导致胃肠道相关疾病(胃和十二指肠溃疡、粘膜相关组织淋巴瘤和胃腺癌)。大多数幽门螺旋杆菌感染的人不会有任何体征或症状。虽然这种细菌感染了世界50%的人口，但在非洲，由于感染是在儿童时期获得的，其流行率高达80%。由于抗菌素耐药性的增加，幽门螺杆菌根除治疗变得越来越具有挑战性。治疗方案有望克服日益流行的耐药幽门螺杆菌菌株，并实现>90%的根除率。虽然治疗方案提供了可接受的幽门螺杆菌根除率，但所使用的方案应有助于幽门螺杆菌对抗菌剂和其他治疗的未来耐药性。
{"title":"Prospectives of Helicobacter pylori","authors":"S. Elakkiya, R. S. Kumar, N. Venkateswaramurthy","doi":"10.51268/SRP.2021.8.2","DOIUrl":"https://doi.org/10.51268/SRP.2021.8.2","url":null,"abstract":"Helicobacter pylori (H. pylori) is a gram negative bacteria whose infection is highly prevalent among the human population and leads to gastrointestinal tract related diseases (gastric and duodenal ulcers, mucosa associated tissue lymphoma and gastric adenocarcinoma). Most people with H. pylori infection will never have any signs or symptoms. While this bacterium infects 50% of the world’s population, in Africa its prevalence reach as high as 80% as the infection is acquired during childhood. H. pylori eradication treatment is becoming more challenging due to increasing antimicrobial resistance. Treatment regimens are expected to overcome the increasing prevalence of resistant strains of H. pylori and achieve a >90% eradication rate. Although treatment regimens provide acceptable H. pylori eradication rates, the regimens used should contribute to future resistance of H. pylori to antimicrobials and other therapies.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82980788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Prawiro, K. Anam, Bobi Prabowo, R. Bramanthi, Avin Ainur Fitrianingsih, D. Hidayati, Siwipeni Imawati, Etty Fitria, S. Winarsih
Backgrounds: Covid-19 has become pandemic in the world, including Indonesia. Some Indonesia Covid-19 people tried to consume Honey, Sausseria coctus, and Nigella sativa for curing the Covid-19 disease. From many testimonies, citizen Indonesia people with no need to take hospitalization have reported a cure if they consumed it. Aims: To make evidence-based medicine that Honey, Sausseria coctus dan Nigella may cure the Covid-19 Methods: We used to post only control design and mice as an animal model. The research divided mice into two groups, and the first group as control received PBS as a placebo. Then the second group, we gave Honey, Sausseria coctus dan Nigella sativa. All of the regiment enters the mouth with special sonde to reach the gastrointestinal organ. After administration regiments a long three weeks, we sacrificed the mice. We evaluated cellular immune responses that are Th2, Th17, and NK cells. We check for humoral immune response, TGF-β, IL-17A, sIgA, IL-4, IL-4, B-def, and IgG. Results: We got deference Th2 and Th17 between control with treatment group (p=0.05). For markers, humoral immunity all has deference between control with treatment group (p=>0.05) statistically, but one (IL-17A) have no statistical difference. Conclusions: We want to continue studying immune responses in humans with COVID-19 if giving Honey, Sausseria coctus, and Nigella sativa.
{"title":"Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?","authors":"S. Prawiro, K. Anam, Bobi Prabowo, R. Bramanthi, Avin Ainur Fitrianingsih, D. Hidayati, Siwipeni Imawati, Etty Fitria, S. Winarsih","doi":"10.31838/SRP.2021.1.224","DOIUrl":"https://doi.org/10.31838/SRP.2021.1.224","url":null,"abstract":"Backgrounds: Covid-19 has become pandemic in the world, including Indonesia. Some Indonesia Covid-19 people tried to consume Honey, Sausseria coctus, and Nigella sativa for curing the Covid-19 disease. From many testimonies, citizen Indonesia people with no need to take hospitalization have reported a cure if they consumed it. Aims: To make evidence-based medicine that Honey, Sausseria coctus dan Nigella may cure the Covid-19 Methods: We used to post only control design and mice as an animal model. The research divided mice into two groups, and the first group as control received PBS as a placebo. Then the second group, we gave Honey, Sausseria coctus dan Nigella sativa. All of the regiment enters the mouth with special sonde to reach the gastrointestinal organ. After administration regiments a long three weeks, we sacrificed the mice. We evaluated cellular immune responses that are Th2, Th17, and NK cells. We check for humoral immune response, TGF-β, IL-17A, sIgA, IL-4, IL-4, B-def, and IgG. Results: We got deference Th2 and Th17 between control with treatment group (p=0.05). For markers, humoral immunity all has deference between control with treatment group (p=>0.05) statistically, but one (IL-17A) have no statistical difference. Conclusions: We want to continue studying immune responses in humans with COVID-19 if giving Honey, Sausseria coctus, and Nigella sativa.","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83299613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Our aim of this study was to do a detailed evaluation of Pandanus tectoriusthe antioxidant, antibacterial,phytochemical constituents and Disk diffusioncytotoxicity properties of Pandanustectorius, which in DPPH commonEnglish known as thatch screwpine or pandanus.MCF-7 cell lineThe fruit got a common name as Hala Fruit. DPPH (1,1- diphenyl-2- picrylhydrazyl) method,the most widely reported free radical scavenging activity was used to measure and determine the antioxidant activity. Disc diffusion method was used to measure the antibacterial activity and the cytotoxicity was measured by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium(MTS). The result showed that seed extracts had a higher level of phenolics, while leaves extract possessed higher flavonoid content. Seed extracts showed the highest antioxidant activity, strong antibacterial activity, and no cytotoxic activity. Therefore looking at the test result, a clear inference can be drawn that Pandanustectorius seeds have excellent characteristics to act as an antibacterial and antioxidant agent. How to Cite this Article Pubmed Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. SRP. 2019; 10(1): 289-295. doi:10.5530/srp.2019.1.45 Web Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. http://www.sysrevpharm.org/?mno=302645000 [Access: March 29, 2021]. doi:10.5530/srp.2019.1.45 AMA (American Medical Association) Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. SRP. 2019; 10(1): 289-295. doi:10.5530/srp.2019.1.45 Vancouver/ICMJE Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. SRP. (2019), [cited March 29, 2021]; 10(1): 289-295. doi:10.5530/srp.2019.1.45 Harvard Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani (2019) Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. SRP, 10 (1), 289-295. doi:10.5530/srp.2019.1.45 Turabian Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. 2019. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. Systematic Reviews in Pharmacy, 10 (1), 289-295. doi:10.5530/srp.2019.1.45 Chicago Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina
摘要本研究的目的是对虎爪草(pananus tectorius)的抗氧化、抗菌、植物化学成分和盘状扩散细胞毒性进行详细的评价。这种水果有一个共同的名字，叫做哈拉水果。采用DPPH(1,1-二苯基-2-吡啶肼基)法测定其抗氧化活性，DPPH法是目前报道最广泛的自由基清除方法。采用圆盘扩散法测定其抑菌活性，用3-(4,5-二甲基噻唑-2-基)-5-(3-羧基甲氧基苯基)-2-(4-磺苯基)- 2h -四唑啉(MTS)测定其细胞毒性。结果表明，种子提取物的酚类物质含量较高，而叶片提取物的类黄酮含量较高。种子提取物具有较高的抗氧化活性、较强的抗菌活性，且无细胞毒活性。因此，从试验结果来看，可以明确地推断，熊猫种子具有优良的抗菌和抗氧化剂的特性。Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani。虎爪草的植物化学成分、抗氧化、抗菌和细胞毒性。SRP。2019;10(1): 289 - 295。Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani。虎爪草的植物化学成分、抗氧化、抗菌和细胞毒性。http://www.sysrevpharm.org/?mno=302645000[访问日期:2021年3月29日]。doi:10.5530/srp.2019.1.45 AMA(美国医学协会)Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani。虎爪草的植物化学成分、抗氧化、抗菌和细胞毒性。SRP。2019;10(1): 289 - 295。风格Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani。虎爪草的植物化学成分、抗氧化、抗菌和细胞毒性。SRP。(2019)，[引自2021年3月29日];10(1): 289 - 295。Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani (2019) Pandanus tectorius的植物化学成分、抗氧化、抗菌和细胞毒性。生物工程学报，10(1)，289-295。Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. 2019. doi:10.5530/srp.2019.1.45虎爪草的植物化学成分、抗氧化、抗菌和细胞毒性。药学系统评价，10(1)，289-295。Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani。虎爪草的植物化学成分、抗氧化、抗菌和细胞毒性。药学系统评论10(2019)，289-295。doi:10.5530/srp.2019.1.45 MLA(现代语言协会)Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani。虎爪草的植物化学成分、抗氧化、抗菌和细胞毒性。药学系统评论10.1(2019)，289-295。打印。doi:10.5530/srp.2019.1.45 APA(美国心理学会)Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani (2019) Pandanus tectorius的植物化学成分、抗氧化、抗菌和细胞毒性。药学系统评价，10(1)，289-295。doi: 10.5530 / srp.2019.1.45
{"title":"Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius","authors":"S. Rahayu","doi":"10.5530/SRP.2019.1.45","DOIUrl":"https://doi.org/10.5530/SRP.2019.1.45","url":null,"abstract":"Our aim of this study was to do a detailed evaluation of Pandanus tectoriusthe antioxidant, antibacterial,phytochemical constituents and Disk diffusioncytotoxicity properties of Pandanustectorius, which in DPPH commonEnglish known as thatch screwpine or pandanus.MCF-7 cell lineThe fruit got a common name as Hala Fruit. DPPH (1,1- diphenyl-2- picrylhydrazyl) method,the most widely reported free radical scavenging activity was used to measure and determine the antioxidant activity. Disc diffusion method was used to measure the antibacterial activity and the cytotoxicity was measured by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium(MTS). The result showed that seed extracts had a higher level of phenolics, while leaves extract possessed higher flavonoid content. Seed extracts showed the highest antioxidant activity, strong antibacterial activity, and no cytotoxic activity. Therefore looking at the test result, a clear inference can be drawn that Pandanustectorius seeds have excellent characteristics to act as an antibacterial and antioxidant agent. How to Cite this Article Pubmed Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. SRP. 2019; 10(1): 289-295. doi:10.5530/srp.2019.1.45 Web Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. http://www.sysrevpharm.org/?mno=302645000 [Access: March 29, 2021]. doi:10.5530/srp.2019.1.45 AMA (American Medical Association) Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. SRP. 2019; 10(1): 289-295. doi:10.5530/srp.2019.1.45 Vancouver/ICMJE Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. SRP. (2019), [cited March 29, 2021]; 10(1): 289-295. doi:10.5530/srp.2019.1.45 Harvard Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani (2019) Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. SRP, 10 (1), 289-295. doi:10.5530/srp.2019.1.45 Turabian Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina, Noverita, Muhammad Reza Jaelani. 2019. Phytochemical constituents, antioxidant, antibacterial and cytotoxicity properties of Pandanus tectorius. Systematic Reviews in Pharmacy, 10 (1), 289-295. doi:10.5530/srp.2019.1.45 Chicago Style Sri Endarti Rahayu, Ernawati Sinaga, Sarayevo Herzagovina","PeriodicalId":22121,"journal":{"name":"Systematic Reviews in Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91522525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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