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Frequency of Pulmonary Manifestations of in Patients with Gastroesophageal Reflux Disease 胃食管反流病患者肺部表现的频率
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.5.11
M. Liaqat, Khajista Zulfiqar, Waleed Asghar
Introduction: Pulmonary manifestations of GERD are attracting increasing attention. The physiological link between GERD and pulmonary disease has been extensively studied in chronic cough and asthma. The gastric contents can cause throat irritation, postnasal drip and hoarseness also recurrent cough. Objectives: This study is to determine frequency of pulmonary manifestations in patients with Gastroesophageal Reflux Disease. Settings: This cross-sectional study was conducted in Aeer ud din Medical college during June 2019 to December 2019. All patients with heartburn, both males and females of 20-70 years of age. Results: Out of 150 patients’ laryngeal symptoms were 10% have dry cough 8% have hoarseness and dry cough hoarseness both in 10% in patients with heartburn. 34% patients with GERD were found to be asthmatic. Nasal symptoms were infrequent 2%. Out of 150 patients 36% do not have any pulmonary manifestations. Conclusion: There is high prevalence of pulmonary manifestations in patients with GERD.
导读:GERD的肺部表现越来越受到人们的关注。在慢性咳嗽和哮喘中,胃食管反流与肺部疾病之间的生理联系已被广泛研究。胃内容物可引起喉咙发炎、鼻后滴涕和声音嘶哑,也可引起反复咳嗽。目的:本研究旨在确定胃食管反流病患者肺部表现的频率。背景:本横断面研究于2019年6月至2019年12月在纽约医学院进行。所有胃灼热患者,年龄20-70岁,男女均可。结果:150例喉部症状患者中,有干咳症状者占10%,有干咳症状者占8%,有干咳症状者占10%。34%的胃反流患者存在哮喘。鼻腔症状不常见,占2%。在150例患者中,36%没有任何肺部表现。结论:反流胃食管反流患者以肺部表现为主。
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引用次数: 0
Role of Artificial Intelligence in Upper Gastrointestinal Diseases: Present and Future 人工智能在上消化道疾病中的作用:现在和未来
Pub Date : 2021-01-01 DOI: 10.51268/SRP.2021.4.15
Jin Lee
There has been extensive research and progress in the medical application of Artificial Intelligence (AI) technology. Radiologic and endoscopic diagnosis based on image analysis has been one of the main areas of focus. In the field of Gastrointestinal (GI) endoscopy, AI has been applied to gastroscopy, capsule endoscopy, and colonoscopy. There are relatively fewer studies in which AI is applied to upper GI diseases, and analysis has mainly focused on the detection of esophageal or gastric neoplasms in upper GI endoscopy. AI is also used to assess the depth of cancer invasion, detect Helicobacter pylori (H. pylori) infection, and diagnose the characteristics of subepithelial lesions. In the near future, AI is expected to expand to the field of disease treatment.
人工智能(AI)技术在医疗领域的应用已经取得了广泛的研究和进展。基于图像分析的放射学和内窥镜诊断一直是人们关注的主要领域之一。在胃肠道内镜领域,人工智能已应用于胃镜、胶囊内镜、结肠镜等领域。人工智能应用于上消化道疾病的研究相对较少,分析主要集中在上消化道内镜下对食管或胃肿瘤的检测。人工智能还用于评估肿瘤侵袭深度,检测幽门螺杆菌(h.p ylori)感染,诊断上皮下病变特征。在不久的将来,人工智能有望扩展到疾病治疗领域。
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引用次数: 0
The Influence of Online Mass Media on Anti-Corruption Legal Awareness Education 网络大众传媒对反腐败法制意识教育的影响
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.2.60
Eddy Rifai, Pitriadin, A. Triono
This research examines the influence of online mass media on anti-corruption legal awareness education. The study uses an empirical and normative juridical approach with calculations using chi-square statistics. The results showed that criminal law enforcement would run effectively if the community has legal awareness in combating crime. Online mass media can play a role in increasing the community's legal awareness through its duties and functions as a means of communication and information. Reading online mass media affects the legal awareness of anti-corruption society in the form of anti-corruption, a positive attitude towards anti-corruption, and perceptions of anti-corruption. Based on the calculation results, there is a significant difference between reading online mass media with anti-corruption legal awareness, which is realized through knowledge, positive attitude, and anti-corruption perception. There is a significant difference in level because some knowledgeable and have a positive attitude towards anti-corruption, lack an anti-corruption understanding.
本研究考察网络大众传媒对反腐法制意识教育的影响。该研究使用经验和规范的司法方法,使用卡方统计计算。调查结果显示,若市民在打击罪案方面有法律意识,便可有效执法。网络大众传媒可以通过其作为传播和信息手段的职责和功能,在提高社会的法律意识方面发挥作用。阅读网络大众传媒以反腐的形式影响着社会对反腐的法律意识、对反腐的积极态度和对反腐的认知。根据计算结果,阅读网络大众媒体与反腐败法律意识之间存在显著差异,通过知识、积极态度和反腐败感知来实现。存在明显的水平差异,因为有的人对反腐败知识渊博,态度积极,对反腐败认识不足。
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引用次数: 1
Assessment of vitamins D and E acute supplementation on testosterone levels in male rats 急性补充维生素D和E对雄性大鼠睾酮水平的影响
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.2.47
A. G. Al-Charak, Z. Kadhim, Shaimaa H. Ali Al-Cekal
Background and objective: In recent years, vitamin D has been considered an interesting subject of study due to its pleiotropic role including autocrine, paracrine and endocrine function in several target organs and systems. The essential molecule for reproduction in animals and it have an antioxidant properties in all mammalian cells is known vitamin E. This study aimed the study the effects of acute supplementation of both vitamins D and E on developing of testosterone levels and reproductive properties in rats. Methods: Forty rats were divided into four groups, 1st group were feeding by acute supplementation with vitamin D while 2nd group supplementation of vitamin E, 3rd group feeding with acute supplementation of both vitamins, and 4th group was control with normal fed. HPLC technique was used to assessing of vitamins D and E levels while levels of TES were investigated by ELISA. Results: The levels of vitamins D (ng/ml) levels in this experiment (after month of supplementation) of study groups (VDS, VES, VDES, and Control) were 7.27±2.1 ,3.15±1.1, 6.19±0.9, 5.11±1.4, respectively, while vitamin E (ng/ml) levels were 4.13±1.2, 6.4±1.3 ,3.15±1.1, 4.17±1.3, respectively, and the p-value was < 0.05 when comparing between all groups. TES levels (pg/ml) were 13.40±3.9, 16.04±2.6, 17.18±3.5, 11.17±2.7 in study groups and the p-value also
背景与目的:近年来,维生素D因其在多种靶器官和系统中的自分泌、旁分泌和内分泌功能而成为研究的热点。维生素E是动物繁殖的基本分子,在所有哺乳动物细胞中都具有抗氧化特性。本研究旨在研究急性补充维生素D和E对大鼠睾丸激素水平和生殖特性的影响。方法:将40只大鼠分为4组,第一组急性补充维生素D,第二组补充维生素E,第三组两种维生素均急性补充,第四组以正常饲料为对照,采用HPLC法测定维生素D、E水平,ELISA法测定TES水平。结果:本实验各组(VDS、VES、VDES、Control)维生素D水平(添加一个月后)分别为7.27±2.1、3.15±1.1、6.19±0.9、5.11±1.4,维生素E水平(ng/ml)分别为4.13±1.2、6.4±1.3、3.15±1.1、4.17±1.3,各组间比较p值均< 0.05。研究组TES水平(pg/ml)分别为13.40±3.9、16.04±2.6、17.18±3.5、11.17±2.7,p值也为p值
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引用次数: 0
Application of Compulsory Licensing in the Context of the Covid-19 Coronavirus Pandemic Covid-19冠状病毒大流行背景下强制许可的应用
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.1.53
N. Serohina, O. Pikhurets, S. Iasechko, E. Yevlakhova, S. Lytvyn, I. Miroshnykov
The article reveals the features and legal grounds for the application of the mechanism of restriction of patent rights through compulsory licensing of inventions. The analysis of the legislation on the regulation of these relations is carried out. The EU experience in the use of compulsory licensing is analyzed and prospects for Ukraine are considered. Theoretical positions on the subject of research are analyzed. It is substantiated that in emergency situations the state should defend the public interests to the detriment of the interests of the patent owner and may apply a compulsory license. Compulsory licensing is a common practice and an important legal institution. The conditions and features of granting a compulsory license for objects of patent law in accordance with the provisions of Ukrainian legislation are revealed. The terms of the compulsory license are not based on the mutual consent of the licensor and the licensee but are determined by the competent state body. The correlation of the Ukrainian legislation with the international obligations of Ukraine is investigated. Analysis of foreign sources shows that compulsory licensing is one of the effective mechanisms for reaching a compromise between the public interests and the patent owner. The paper confirms the expediency of shifting the balance of interests from the patent owner to society in the context of the COVID-19 pandemic. Recommendations for improving Ukrainian legislation are provided.
本文揭示了发明强制许可限制专利权机制的特点及其适用的法律依据。对这些关系的立法规制进行了分析。分析了欧盟在使用强制许可方面的经验,并考虑了乌克兰的前景。分析了研究课题的理论立场。事实证明,在紧急情况下,国家应当维护公共利益,损害专利权人的利益,可以实行强制许可。强制许可是一种普遍做法,也是一项重要的法律制度。揭示了根据乌克兰立法规定授予专利法对象强制许可的条件和特点。强制许可的条件不是基于许可人和被许可人的相互同意,而是由国家主管机关确定。研究了乌克兰立法与乌克兰国际义务的关系。国外资料分析表明,强制许可是公共利益与专利权人达成妥协的有效机制之一。这篇论文证实了在新冠肺炎大流行的背景下,将利益平衡从专利权人转移到社会的权宜之计。提出了改进乌克兰立法的建议。
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引用次数: 1
Features Of The Formation Of Single-Species And Heterogeneous Agrocenoses Of Medick And Perennial Meadow-Grasses In Field Forage Production 野地牧草生产中禾本科与多年生草甸草单种与异种复合禾本科的形成特征
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.3.68
N. Saoudi
The relevance of research is due to the need to improve individual elements of agrotechnology for medick and perennial meadow-grasses cultivation depending on the background of mineral nutrition, and for the creation of highly productive herbage in the gray forest soils of the southwestern part of the Central region of the Russian Federation. Perennial legumes in single-species and heterogeneous crops are the main components in solving the problem of vegetable protein in the production of the highest quality feed. The methodology of field experiments is based on the principle of intensification and biologization of agriculture. The research aims at developing elements of agricultural technologies for the cultivation of perennial grasses in single-species and heterogeneous crops and at improving the biochemical composition of forages, depending on both the species composition of the grass mixture and the effect of the background of mineral fertilizers on the yield in single-species and heterogeneous field agrocenoses. The research methods were field, laboratory, and statistical. Field studies were carried out on the experimental field of Bryansk State Agrarian University using a modern assortment of medick and perennial meadow-grasses on various backgrounds of mineral fertilizers. In the grass mixtures, the legume component varied from 40 to 50%. Sowing was carried out under the cover of one-year-old Westerwolds ryegrass (Lolium multiflorum Lam. var. westerwoldicum Wittm). Medick (Medicago varia Mart.) was used as the legume component. Meadow-grasses are represented by timothy (Phleum pratense L.), meadow fescue (Festuca pratensis Huds.), cat grass (Dactylis glomerata L.), and awnless brome (Bromus inermis). The formation of the yield of green mass and dry matter of medick and perennial meadow-grasses mixtures is justified by the background of mineral nutrition and the species composition of cultivated grass mixtures. On average, over the years of field experiments, the maximum yield (45.32 t/ha) of green mass and of dry matter (11.33 t/ha) was obtained in the variant of medick-fescue grass mixture against the background of prolonged action of Borofoska in combination with annual nitrogen fertilization at the dose N30. Under the influence of mineral fertilizers, an improvement in the biochemical composition of dry matter of heterogeneous crops of legume-perennial meadow-grasses was noted. The highest indices of nutrients were found in the forage mass of the medick-timothy grass mixture
研究的相关性是由于需要改进农业技术的个别要素,以便根据矿物营养背景进行药用和多年生草甸种植,并在俄罗斯联邦中部地区西南部的灰色森林土壤中种植高产牧草。单种和异种作物中的多年生豆科植物是解决生产高品质饲料中植物蛋白问题的主要组成部分。田间试验的方法是基于农业集约化和生物化的原则。该研究的目的是根据混合草的种类组成和矿质肥料背景对单种和异种农田混耕作物产量的影响,开发多年生草栽培的农业技术要素,并改善饲料的生化组成。研究方法有现场法、实验室法和统计法。在布良斯克国立农业大学的试验田进行了实地研究,在不同背景的矿物肥料上使用了各种现代药物和多年生草地。在混合草中,豆科植物的含量在40 - 50%之间。播种在一年生的西部黑麦草(Lolium multiflorum Lam)的掩护下进行。紫檀变种。药用植物(Medicago varia Mart.)作为豆科成分。草甸类的代表植物有:蒂莫西草(Phleum pratense L.)、草地羊茅(Festuca pratensis Huds.)、猫草(Dactylis glomerata L.)和无芒雀麦(Bromus inermis)。草本植物和多年生草甸混交种的绿质和干物质产量的形成与草甸混交种的矿质营养背景和种属组成有关。多年田间试验平均结果显示,在长时间施用硼砂和每年施氮量为N30的情况下,药羊茅混合品种的绿质量和干物质产量最高,分别为45.32 t/ha和11.33 t/ha。在矿质肥料的影响下,豆科-多年生草甸杂交种作物的干物质生化组成有所改善。各营养指标均以药-草混合物的牧草质量最高
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引用次数: 0
The Complex Effect Of Retinyl Acetate And Zeolite On The Resistance Of Rabbits With Aflatoxicosis 醋酸视黄醇和沸石对黄曲霉中毒家兔抗性的复合作用
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.3.40
A. Mukharlyamova, A. Tremasova, Aigul G. Mukhammetshina Oksana V. Shlyamina, Alsu R. Makaeva, S. A. Tanaseva, A. M. Sayfutdinov, I. Fitsev, A. Likhacheva, E. Rakhmetova, S. L. Mokhtarova, M. S. Khakimov
The article presents the results of studying the effect of a combination of zeolite from the Tatar-Shatrashansky deposit of the Republic of Tatarstan and retinyl acetate in rabbit aflatoxicosis on the indicators of natural resistance of animals. The duration of the experiment was 55 days. Animals of the first group received the main diet, of the second group received a toxic diet, animals of the third group were additionally injected retinyl acetate with a toxic diet at a dose of 1500 IU per individual, the rabbits of the fourth group, in addition to the toxic diet, received retinyl acetate at a dose of 1500 IU per individual and zeolite at a dose of 2% of the diet. Studies showed, that the complex use of retinyl acetate and zeolite is highly effective in case of aflatoxicosis, contributing to the normalization of clinical, biochemical indicators and non-specific resistance factors.
本文介绍了鞑靼斯坦共和国鞑靼-沙特拉山斯基(Tatar-Shatrashansky)矿床沸石与兔黄曲霉中毒中醋酸视黄酯复合使用对动物自然抗性指标影响的研究结果。试验期55 d。第一组饲喂主饲粮,第二组饲喂毒性饲粮,第三组在此基础上注射毒性饲粮,剂量为1500 IU /只,第四组在毒性饲粮的基础上,注射剂量为1500 IU /只的醋酸视黄酯和2%的沸石。研究表明,在黄曲霉中毒病例中,醋酸视黄酯和沸石复合使用非常有效,有助于临床、生化指标和非特异性耐药因素的正常化。
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引用次数: 0
Using Of Area Under The Curve Method For The Spectrophotometric Determination Of Betamethasone Sodium Phosphate In Its Pure And Pharmaceutical Forms 曲线下面积法测定倍他米松磷酸钠纯品和制剂的含量
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.1.40
Khalaf F. Alsamarrai, Harith Jameel Mahdi Alsamarraie, M. A. Al-Abbasi
A new, fast, accurate, economic, sensitive spectrophotometric method for the determination of Betamethasone (BSP) was developed. The method includes the use of the area under the curve (AUC) of the BMT UV-spectrum in methanol. This method was very suitable to the determination of BSP because it gave good linearity which up to 10-100 µg/ml, good accuracy and precision, through Rec% values which were ranged between 98.40914-101.40864% and RSD% values were ranged between 0.05507-0.97609%, LOD was 0.029701 µg/ml and LOQ was 0.098013 µg/ml. The method successfully applied to the determination of BSP in pure and trading forms.
建立了一种快速、准确、经济、灵敏的分光光度法测定倍他米松(BSP)的方法。该方法包括使用甲醇中BMT紫外光谱的曲线下面积(AUC)。该方法线性范围为10 ~ 100µg/ml,准确度和精密度良好,Rec%范围为98.40914 ~ 101.40864%,RSD%范围为0.05507 ~ 0.97609%,LOD为0.029701µg/ml, LOQ为0.098013µg/ml。该方法适用于纯品和交易品中BSP含量的测定。
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引用次数: 0
Analysis of Mucinous Cystadenoma of Pancreas with Honeycombing Appearance 具有蜂窝状外观的胰腺粘液囊腺瘤分析
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.5.7
Awais Jamil, Atique ur-Rehman, Usama Shahid, S. Hussain
Introduction: Large quality of imaging examination helps in the discovery of Cystic Pancreatic Lesions (CPLs). Objectives: The main objectives of the study is to evaluate the mucinous cystadenoma of pancreas with honeycombing appearance. Methodology: This prospective study was conducted in Bahawal Victoria Hospital, Bahawalpur during 2019 to 2020. All the cases of cystic pancreatic lesions were observed by Ultrasound and contrast-enhanced CT and contrast-enhanced MRI.
高质量的影像学检查有助于发现囊性胰腺病变(cpl)。目的:本研究的主要目的是评估胰腺粘液囊腺瘤,其外观为梳状。方法:这项前瞻性研究于2019年至2020年在巴哈瓦尔布尔的巴哈瓦尔维多利亚医院进行。所有病例均行超声、CT增强及MRI增强检查。
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引用次数: 0
Morphometric And Comparative Study Of Nutrient Foramina Of Femur And Humerus Bones And Its Clinical Importance In Egyptian Population 埃及人群股骨、肱骨营养孔形态计量学与比较研究及其临床意义
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.3.23
E. Ali
Background : knowledge with respect to nutrient foramina of bones is helpful in surgeries, for example, microvascular bone exchange to safeguard the dissemination. In any case, there is not many information on Morphometric investigates of the supplement foramina of femur and humerus in Egyptians. Subjects and methods : Between June 2019 and September 2020, we prospectively assess morphology of nutrient foramina included 350 adult long limb bones of femur and humerus Department of Anatomy in Al-Azhar University . the age and gender of which were not determined of Egyptian subjects. The bones were examined for the number, location and direction of the nutrient foramina. Aim of the work : To investigate the morphology of nutrient foramina of femur and humerus regarding to their numbers and localizations and to determine their foraminal index to provide detailed data on such features. Results : The foramina were most determined in anteromedial aspect 61% of cases on the shaft of bone in the humerus , its foramial indices were 32.1 – 68.7 % and the most of study (84%) had one nutrient foramen. In femur, we founded that the range of foraminal indices of bone 26.1 – 68 % , mainly sample (88% ) located in the middle third of the bone and (30%) had one nutrient foramen, (60%) had two nutrient foramina and only (10%) had three nutrient foramina. 56.1% nutrient foramina were located in between upper and middle 1/3rd of the Femur,,18.7% nutrient foramina were located in between middle and lower 1/3rd of the Femur ,, 23% nutrient foramina were located in middle half of the length of the Femur. Foraminal Index (FI): (Distance of nutrient foramen / Total length) ×100 Conclusion: The anatomical information of the nutrient foramen of the long bones of limb as femur and humerus is important for orthopaedic surgeons during surgical operations of bones.
背景:对骨营养孔的了解有助于外科手术,如微血管骨交换,以保障播散。无论如何,埃及人股骨和肱骨补充孔的形态计量学研究资料并不多。对象与方法:2019年6月至2020年9月,我们前瞻性评估了350例成人股骨和肱骨长肢骨的营养孔形态。埃及人的年龄和性别尚未确定。研究人员检查了这些骨头的营养孔的数量、位置和方向。目的:研究股骨和肱骨营养孔的数量和定位的形态学特征,确定其营养孔指数,为这些特征提供详细的数据。结果:在肱骨骨轴上,有61%的病例在前内侧方向确定有孔,其孔指数为32.1% ~ 68.7%,84%的病例有一个营养孔。在股骨中,我们发现骨孔指数的范围为26.1 ~ 68%,主要样本(88%)位于骨的中间三分之一,(30%)有一个营养孔,(60%)有两个营养孔,只有(10%)有三个营养孔。56.1%的营养孔位于股骨上1/3和中1/3之间,18.7%的营养孔位于股骨中1/3和下1/3之间,23%的营养孔位于股骨长度的中间一半。椎间孔指数(FI):(营养孔距离/总长度)×100结论:股骨、肱骨等肢体长骨营养孔的解剖信息对骨科医生在骨科手术中具有重要意义。
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引用次数: 2
期刊
Systematic Reviews in Pharmacy
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