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Improving Foot Peripheral Blood Circulation with Indicators of Ankle Brachial Index (ABI) through Diabetic Foot Spa in Diabetes Mellitus Patients of Type 2 糖尿病足Spa对2型糖尿病患者踝肱指数指标改善足周血液循环的影响
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.1.190
A. A. A. Hidayat, Ricky Riyanto Iksan, Buntar Handayani, Isnayati, Rona Febriyona
This work aims to analyse the impact of foot peripheral blood circulation with indicators of Ankle Brachial Index (ABI) through diabetic foot spa in diabetes mellitus patients of type 2. The research design involved experimental research with a one-group pre-post-test layout. The samples comprised 62 respondents, and the purposive sampling technique was employed. The intervention was in the form of presenting a diabetic foot spa procedure, which was carried out by means of foot exercises, which were carried out by means of foot exercises, skin cleansing, and foot massage, which were carried out for 45 minutes every day, for 5 days. The instrument used to measure blood circulation in the feet is used by the Ankle Brachial Index (ABI) measurement tool by comparing the measurement of ankle temperature measurement (right or left) with the highest systole measurement value on the right or left. The statistical test for the paired t-test obtained a p value of 0.001. This demonstrates that diabetic foot spa that was effective in improving peripheral blood circulation in patients with type DM diabetes. Therefore, the diabetic foot spa can be used as an alternative in improving peripheral blood circulation in diabetes mellitus patients of type 2.
本研究旨在分析糖尿病足spa对2型糖尿病患者踝肱指数(Ankle Brachial Index, ABI)足周血液循环的影响。研究设计包括一组测试前-测试后布局的实验研究。样本共62人,采用目的性抽样方法。干预以糖尿病足部spa程序的形式进行,该程序通过足部运动进行,该运动通过足部运动,皮肤清洁和足部按摩进行,每天45分钟,持续5天。踝肱指数(Ankle Brachial Index, ABI)测量工具是用来测量足部血液循环的仪器,通过将测量的踝关节温度(右或左)与右或左的最高收缩期测量值进行比较。配对t检验的统计检验得到的p值为0.001。这表明糖尿病足spa对改善DM型糖尿病患者外周血循环是有效的。因此,糖尿病足浴可作为改善2型糖尿病患者外周血循环的一种替代方法。
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引用次数: 1
A Sensitivity and Specificity Diagnosis of Pews is Used to Indicate the Necessity for Hospital Admission and to Predict Serious Disease Among Children 应用敏感性和特异性诊断提示儿童是否需要住院治疗和预测严重疾病
Pub Date : 2021-01-01 DOI: 10.51268/SRP.2021.6.6
U. Javaid, A. Amjad, M. Mahmood, Farrukh Addil, Sameer Ahmed
Aim: The advance warning score (Seats), which is legitimized in the crisis department, is less accepted for the prevention of early weakening of a hospitalized teenager. The affectivity and information activity of two PEWSs, usually used in hospital admissions and the first serious disease, were expected to be evaluated. Methods: Required data was disclaimed for patients. Our current research was conducted at Mayo Hospital, Lahore from May 2020 to April 2021. Clinical and rigorous analyses have been performed. We have applied guidelines and usual understanding amongst three intense careers to identify assessments as crucial where not available. Results: 1940 patients have been shattered. 213 confirmations were received (12 percent). There were 1640 clinical (87%) and 277 (15%) cautious therapies. Relatively performing Brighton and COAST Seats. Emergency Clinic Verification-PEWS so 4 (94 INTRODUCTION Since the Brighton Score approval in 20051, other children's early warning scores have been utilized to detect the early deterioration of the infant in hospital. Together with the Pakistan Maternal and Childhood Report, 'Why children bite dust,' the Pakistan National Patient Safety Agency and the Public Hospital and Care Excellence Institute suggested early detection levels to assist children with the beginnings of the underlying illness in the clinic (Considine J, et al, 2019). Although their unlimited performance, the qualitative alterations thought proper, making approval varied for various scores. Introducing an urgent concentration of 4 hours in Pakistan. In order to achieve the continued management decision, a 5-hour emphasis in Pakistan emergency departments is introduced (Pinto C, et al., 2018). 6 Seats using the Brighton- and COAST systems generally employed have been constructed so that trends in the physiological condition of the patient may be reflected and the decay process identified early and the hospitalized kid can thus be quickly identified. In any case, in order to avoid the needs of a health clinic for confirmation, or the severity of the disease, the validity of "pre-vising" the physiological boundaries in the emergency department is not recognized (Burrell AR, et al., 2016). As the usage of PEWS in emergency services rises, the predictive capacity of this instrument must be known to forecast emergency confirmation and a substantial indicant disease. There are just two explicit studies PEWS capability to predict admission in emergency department percent) was clean, though unnoticeable (34 percent). The area below the AUC was low at 0.693. The AUC is low. Major allegation: PEWS was 95 percent very clear, nevertheless, not sensitive enough in clinical diseases (45 percent). The AUC was 0.756 per person for Brighton and COAST PEWS. The two scores were unsuccessful in predicting critical careful nausea (AUC 0.644). Seats=4 have been successful in predicting major respiratory diseases-76%, 92% specified affectivity. Conclusion: Brighto
目的:预警评分(座椅),这是合法的在危机部门,是不太接受预防早期衰弱住院青少年。预计将评估两种通常用于住院和首次严重疾病的PEWSs的影响和信息活动。方法:对患者要求的资料不予填写。我们目前的研究于2020年5月至2021年4月在拉合尔的梅奥医院进行。已经进行了临床和严格的分析。我们在三个激烈的职业中应用了指导方针和通常的理解,以确定评估在不可用的情况下是至关重要的。结果:共粉碎患者1940例。收到213份确认(12%)。临床治疗1640例(87%),谨慎治疗277例(15%)。表现相对较好的布莱顿和海岸席位。自2005年布莱顿评分获得批准以来,其他儿童早期预警评分已被用于检测医院婴儿的早期恶化。巴基斯坦国家患者安全局和公立医院和卓越护理研究所连同《巴基斯坦妇幼报告》《儿童为什么咬尘》,建议早期发现水平,以帮助儿童在诊所开始潜在疾病(Considine J, et al ., 2019)。虽然他们的表现是无限的,但定性的改变是适当的,使得不同的分数得到不同的认可。在巴基斯坦引入4小时的紧急集中。为了实现持续的管理决策,引入了巴基斯坦急诊科5小时的重点(Pinto C, et al., 2018)。使用Brighton-和COAST系统构建的座椅可以反映患者生理状况的趋势,并及早发现衰变过程,从而可以快速识别住院儿童。在任何情况下,为了避免健康诊所确认的需要,或者疾病的严重程度,在急诊科“预先检查”生理边界的有效性不被认可(Burrell AR, et al., 2016)。随着PEWS在紧急服务中的使用增加,必须了解该工具的预测能力,以预测紧急确认和重大指示性疾病。只有两项明确的研究(PEWS预测急诊科入院的能力(34%))是干净的,尽管不明显(34%)。AUC下方的区域较低,为0.693。AUC很低。主要指控:95%的PEWS非常清楚,然而,对临床疾病不够敏感(45%)。布莱顿和COAST PEWS的人均AUC为0.756。这两个评分在预测严重恶心方面均不成功(AUC为0.644)。座椅=4已经成功预测了主要的呼吸系统疾病——76%,92%指定了影响。结论:布莱顿和海岸教堂均有良好的效果。因此,对临床确认和重要疾病预测的有效性不受保护。然而,高PEWS并不是确认实际患病的先决条件。
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引用次数: 0
Finding the Complications of Functional Endoscopic Sinus Surgery in Sinusitis Patients 功能性内窥镜鼻窦手术治疗鼻窦炎的并发症分析
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.5.13
Muqaddas Shahzad Qazi, Javeria Noor, Moazza Latif
Introduction: Functional Endoscopic Sinus Surgery (FESS) is regarded as an invasive technique used in the surgical fraternity to restore patients’ sinus ventilation as well as returning to normalcy. Objectives: The main objective of the study is to find the complications of Functional Endoscopic Sinus Surgery in sinusitis patients. Material and methods: This cross-sectional study was conducted in Jinnah Hospital Lahore during 2019 to 2020. The study was carried in hospital, whereby 200 patients performed Functional Endoscopic Sinus Surgery operation. After the surgery the patients were followed postoperatively and checked for both minor and major complications, and their experiences at large. Results: The data was collected from 200 patients. The mean age of the patients was 39.25±2.45 years. The major complications presented by the patients in three months follow up were shown in table. Conclusion: All together there are few cases of complications from the manipulations performed during the post-operative visits whereby the theoretical risks are equally the same as the main surgery itself. Nearly all surgeries and postoperative care are closely similar and therefore the consent given for surgery automatically includes consent for postoperative care.
简介:功能性内窥镜鼻窦手术(FESS)被认为是外科界用于恢复患者鼻窦通气和恢复正常的一种侵入性技术。目的:探讨功能性鼻内窥镜手术治疗鼻窦炎的并发症。材料和方法:本横断面研究于2019 - 2020年在拉合尔真纳医院进行。本研究在医院进行,其中200例患者进行了功能性内窥镜窦Sur手术。手术后,对患者进行术后随访,检查轻微和严重并发症,以及他们的总体经历。结果:收集了200例患者的数据。患者平均年龄39.25±2.45岁。患者随访3个月出现的主要并发症见表。结论:总的来说,术后随访中操作引起的并发症病例很少,理论风险与主手术本身相同。几乎所有的手术和术后护理都非常相似,因此手术的同意自动包括术后护理的同意。
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引用次数: 0
Management of Severe Acute Respiratory Distress Syndrome in COVID-19: A Literature Review COVID-19患者严重急性呼吸窘迫综合征的治疗:文献综述
Pub Date : 2021-01-01 DOI: 10.51268/SRP.2021.4.7
A. Yar, A. Sohail, Ayesha Shahzad
Serious complication may occurred in COVID-19 patients, including Acute Respiratory Distress Syndrome (ARDS) that causes death. Currently, ARDS from COVID-19 is still an ongoing challenge. Adequate treatment in ARDS management might significantly decreases morbidity and mortality.
COVID-19患者可能出现严重并发症,包括导致死亡的急性呼吸窘迫综合征(ARDS)。目前,COVID-19引起的急性呼吸窘迫综合征仍然是一个持续的挑战。适当的治疗可显著降低ARDS的发病率和死亡率。
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引用次数: 0
Isolation and Identification of Aspergillus spp. from Human and Sheep Respiratory Infection in Al-Qadisiyah Province Al-Qadisiyah省人羊呼吸道感染曲霉菌的分离与鉴定
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.1.132
Riyadh Ajmi Salman, L. D. Z. A. A. Al-haddad
This study was conducted to isolate the most common Aspergillus spp. which cause dangerous diseases such as aspergillosis from respiratory infection in human and sheep, one hundred (100) human sputum sample collected from patients in respiratory diseases center of Al-diwaniyah educational hospital during a period of two (2) months wich where (November and December 2019), and one hundred (100) nasal swabs samples were collected from sheep which appeared clinical signs of respiratory infections from sheep flocks in rural in Al- Qadisiyah province, samples collected from sheep during the period of two months (2) which were January and february2020. The isolated species in human appeared 74 out of 100(74%) positive fungal isolate so Aspergillus fumigatus represents12 isolates (16.21 %), Aspergillus niger, 8 isolates ( 10.81%), Aspergillus flavus 5 isolates (6.75%), Aspergillus ochraceus 2 isolates (2.7%),also another spp. of fungi were isolated which include penicillium spp. and Alternaria spp. 7 isolates (9.45%) for each one of them, Geotrichum spp. 4 isolates (5.4%), Trichophyton mentagrophytes 3 isolates ( 4.05%), Cladosporium spp. 2 isolates (2.7%), whereas Yeasts spp. constitute 22 isolates (29.72%). While the sheep revealed ninety six (96) fungal isolate out of (100) which include: Aspergillus ochraceus 9 isolates (9.37%), Aspergillus niger 6 isolates (6.25%), Aspergillus flavus 3 isolates (3.12%), Aspergillus fumigatus 2 isolates (2.08%), also other fungal species were isolated include : Alternaria spp. 9 isolates(9.37%), Rhizopus spp. 14 isolates(14.58%), Trichophyton mentagrophytes 13isolates(13.54%), penicillium spp. 12isolates (12.5%), Trichophyton verrucosum10 isolates(10.41%), Microsporum caninum 6 isolates(6.25%) , Geotrichum spp. and Cladosporium spp. 1isolate(1.04%) for each one of them and Yeast spp. 10 isolates(10.41%).
本研究是为了从人类和绵羊的呼吸道感染中分离出最常见的导致曲霉病等危险疾病的曲霉属,在2019年11月和12月两个月的时间里,从Al-diwaniyah教育医院呼吸疾病中心的患者中采集了100份人类痰样本。从Al- Qadisiyah省农村羊群中出现呼吸道感染临床症状的羊身上采集了100(100)份鼻拭子样本,这些样本采集于2020年1月和2月两个月期间。在100株(74%)阳性真菌分离物中,从人体分离出74株,其中烟曲霉12株(16.21%),黑曲霉8株(10.81%),黄曲霉5株(6.75%),赭曲霉2株(2.7%),另外还分离出一种真菌,包括青霉菌和Alternaria,各7株(9.45%),土霉4株(5.4%),毛霉3株(4.05%)。枝孢菌2株(2.7%),酵母22株(29.72%)。绵羊共分离真菌96株(100株),其中:赭曲霉9株(9.37%)、黑曲霉6株(6.25%)、黄曲霉3株(3.12%)、烟曲霉2株(2.08%),其他真菌种类还包括:稻霉9株(9.37%),根霉14株(14.58%),茅多菌毛癣菌13株(13.54%),青霉菌12株(12.5%),疣状毛癣菌10株(10.41%),犬小孢子菌6株(6.25%),土霉和枝孢菌各1株(1.04%),酵母菌10株(10.41%)。
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引用次数: 2
Different Methods For Testing The Microbial Effects Of Camel's Milk Against Some Pathogenic Bacteria 骆驼奶对致病菌微生物作用的不同检测方法
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.3.9
A. Hafez
Overuse of antibiotics is causing some bacteria to become resistant to antibiotics, in addition to their price hikes. Therefore, this study was designed to investigate the effect of camel milk as a safe natural product to overcome the pathogens caused by Staphylococcus aureus, Escherichia coli, and Salmonella typhi and to test their effect on them by several ways, in vivo, in vitro, and in histology. In addition to the use of an electron microscope, 48 rats were used and they were divided into eight groups, the first group was considered a negative control. For two consecutive weeks, the second group gets the milk. And by intraperitoneal injection of E. coli and S. aureus group 3 and 4, respectively. Group 5 supplemented the infection by oral administration of Salmonella typhi The sixth, seventh and eighth groups were supplemented with camel milk for two consecutive weeks, then intraperitoneal injection of either E. coli or S. aureus and Salmonella typhi bacteria by mouth, and the spleen was collected after 3 weeks to isolate the bacteria. The isolation rate of S. aureus, E coli, and Salmonella typhi was higher in rats in groups 3, 4, and 5 compared to groups 6, 7, and 8 and with milk diluents (10-100). By the agar diffusion method used to test for antibacterial efficacy, 80% dilution achieved the best result, and by using a transmission electron microscope to detect damage to the bacterial cell wall and disturbance in the cellular protein content. The results indicate that camel milk has an effect on the internal structure and cell wall also in the pathological anatomy. It was found that the pathogenic bacteria had fewer effects in the liver and kidneys in the groups treated with camel milk compared to the groups infected with bacteria only, and therefore we conclude that the camel milk Promising anti-bacterial properties.
抗生素的过度使用导致一些细菌对抗生素产生耐药性,此外抗生素的价格也在上涨。因此,本研究旨在探讨骆驼奶作为一种安全的天然产品,对金黄色葡萄球菌、大肠杆菌和伤寒沙门氏菌等病原菌的抑制作用,并从体内、体外和组织学等方面对其效果进行检验。除电镜观察外,取48只大鼠分为8组,第一组为阴性对照。连续两周,第二组得到牛奶。腹腔注射大肠杆菌组3和金黄色葡萄球菌组4。第6、7、8组连续2周补充骆驼奶,分别腹腔注射大肠杆菌或经口注射金黄色葡萄球菌和伤寒沙门菌,3周后取脾进行细菌分离。3、4、5组大鼠金黄色葡萄球菌、大肠杆菌和伤寒沙门氏菌的分离率高于6、7、8组和牛奶稀释剂组(10-100)。通过琼脂扩散法检测抗菌效果,80%稀释度达到最佳效果,并通过透射电镜检测对细菌细胞壁的损伤和细胞蛋白含量的干扰。结果表明,骆驼奶对细胞的内部结构和细胞壁也有一定的影响。研究发现,与仅感染细菌组相比,骆驼奶组的肝脏和肾脏中致病菌的影响较小,因此我们得出结论,骆驼奶具有良好的抗菌性能。
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引用次数: 0
The Effect Of Policy Implementation Of Information Meteorology Climatology And Geophysics On Economic Resilience 信息气象、气候学和地球物理政策实施对经济恢复力的影响
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.3.28
S. Pudjiastuti, M. Sutisna, Sopian, Pat Kurniati, Sri Rumiat
The purpose of this study was to obtain empirical data on the effect of the implementation of the earthquake and tsunami information utilization policy on the economic resilience of the people of Sukabumi Regency. Research respondents were the people of Sukabumi Regency, from January to March 2020. The research method used was a quantitative descriptive method with a correlational study. The number of samples was 30 people who were randomly assigned. The data collection tool used was a behavioral scale questionnaire for variable X and with the type of behavior scale also from Likert for variable Y. All instruments were tested for their validity and reliability levels at a significance level of 0.95 or 0.05%. To complete the test requirements Hypothesis, a pre-requisite test for data analysis was performed, namely the normality and linearity test. For the normality of each variable, variable X gets a result of 0.0954 and variable Y is 0.0729, which when compared to L table of 0.1610 turns out to be both larger, so that both can be declared normally distributed. For the Linearity Test between the two variables yields A¶ = 38.68 + 0.51X, F counts 0.6888 and F table is 2.95 with dk 28 at ii = 0.05. Since F count is less than F table (0.6888 0.361) it can be concluded that there is an effect of the implementation of policies on the use of earthquake and tsunami information on the economic resilience of the people of Sukabumi Regency. determination of 0.61252 = 0.3751. Thus the contribution of variable X to Y is 37.51%. The level of significance of the influence of the two variables was carried out by using the t-test. The results of the analysis show the t - count is 4.10 with a 95% confidence level in dk (28) and t - table of 2.05. Thus t - count is more than t - table (4.10> 2.05). The comparison of the two "t" values indicates a significant effect. How to Cite this Article Pubmed Style Sri Rahayu Pudjiastuti, Moh. Sutisna, Sopian, Pat Kurniati, Sri Rumiat. The Effect Of Policy Implementation Of Information Meteorology Climatology And Geophysics On Economic Resilience. SRP. 2021; 12(3): 166-175. doi:10.31838/srp.2021.3.28 Web Style Sri Rahayu Pudjiastuti, Moh. Sutisna, Sopian, Pat Kurniati, Sri Rumiat. The Effect Of Policy Implementation Of Information Meteorology Climatology And Geophysics On Economic Resilience. http://www.sysrevpharm.org/?mno=51626 [Access: March 30, 2021]. doi:10.31838/srp.2021.3.28 AMA (American Medical Association) Style Sri Rahayu Pudjiastuti, Moh. Sutisna, Sopian, Pat Kurniati, Sri Rumiat. The Effect Of Policy Implementation Of Information Meteorology Climatology And Geophysics On Economic Resilience. SRP. 2021; 12(3): 166-175. doi:10.31838/srp.2021.3.28 Vancouver/ICMJE Style Sri Rahayu Pudjiastuti, Moh. Sutisna, Sopian, Pat Kurniati, Sri Rumiat. The Effect Of Policy Implementation Of Information Meteorology Climatology And Geophysics On Economic Resilience. SRP. (2021), [
本研究的目的是要取得实验资料,以了解地震与海啸资讯利用政策的实施,对苏kabumi县人民经济复原力的影响。调查对象是2020年1月至3月期间素kabumi县的居民。本研究采用定量描述法和相关研究。样本的数量是随机分配的30人。使用的数据收集工具是变量X的行为量表问卷,变量y的行为量表类型也来自李克特。所有工具的效度和信度水平均在0.95或0.05%的显著性水平上进行测试。为了完成检验需求假设,进行了数据分析的先决条件检验,即正态性和线性检验。对于每个变量的正态性,变量X得到的结果是0.0954,变量Y得到的结果是0.0729,与L表的0.1610相比,这两个结果都更大,因此可以声明它们都是正态分布的。对于两个变量之间的线性检验,得出A¶= 38.68 + 0.51X, F计数为0.6888,F表为2.95,dk 28在i´i = 0.05时。由于F计数小于F表(0.6888 0.361),因此可以得出结论,政策的实施对地震和海啸信息的使用对素kabumi县人民的经济恢复力有影响。测定0.61252 = 0.3751。因此变量X对Y的贡献为37.51%。两个变量影响的显著性水平采用t检验。分析结果显示,t - count为4.10,dk(28)的置信水平为95%,t - table为2.05。因此,t - count多于t - table(4.10> 2.05)。两个“t”值的比较表明效果显著。如何引用本文Pubmed Style Sri Rahayu Pudjiastuti, Moh。Sutisna, Sopian, Pat Kurniati, Sri Rumiat。信息气象、气候学和地球物理政策实施对经济恢复力的影响。SRP。2021;12(3): 166 - 175。doi:10.31838/srp.2021.3.28 Web Style Sri Rahayu PudjiastutiSutisna, Sopian, Pat Kurniati, Sri Rumiat。信息气象、气候学和地球物理政策实施对经济恢复力的影响。http://www.sysrevpharm.org/?mno=51626[访问日期:2021年3月30日]。doi:10.31838/srp.2021.3.28 AMA(美国医学协会)Sutisna, Sopian, Pat Kurniati, Sri Rumiat。信息气象、气候学和地球物理政策实施对经济恢复力的影响。SRP。2021;12(3): 166 - 175。doi:10.31838/srp.2021.3.28 Vancouver/ICMJESutisna, Sopian, Pat Kurniati, Sri Rumiat。信息气象、气候学和地球物理政策实施对经济恢复力的影响。SRP。(2021),[引自2021年3月30日];12(3): 166 - 175。doi:10.31838/srp.2021.3.28哈佛风格Sutisna, Sopian, Pat Kurniati, Sri Rumiat(2021)信息气象、气候和地球物理政策实施对经济恢复力的影响。生物工程学报,12(3),166-175。doi:10.31838/srp.2021.3.28 Turabian Style苏蒂斯纳,索宾,帕特·库尔尼亚提,斯里·鲁米阿特,2021。信息气象、气候学和地球物理政策实施对经济恢复力的影响。药学系统评价,12(3),166-175。doi:10.31838/srp.2021.3.28Sutisna, Sopian, Pat Kurniati, Sri Rumiat。信息气象、气候学和地球物理政策实施对经济恢复力的影响药学系统评论12(2021),166-175。doi:10.31838/srp.2021.3.28 MLA(现代语言协会)Style Sri Rahayu Pudjiastuti, Moh。Sutisna, Sopian, Pat Kurniati, Sri Rumiat。信息气象、气候学和地球物理政策实施对经济恢复力的影响药学系统评论12.3(2021),166-175。打印。doi:10.31838/srp.2021.3.28 APA(美国心理学会)Sutisna, Sopian, Pat Kurniati, Sri Rumiat(2021)信息气象、气候和地球物理政策实施对经济恢复力的影响。药学系统评价,12(3),166-175。doi: 10.31838 / srp.2021.3.28
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引用次数: 1
Association of Ki-67 Level on Bone Destruction in Chronic Suppurative Otitis Media Patients with Cholesteatoma Ki-67水平与慢性化脓性中耳炎合并胆脂瘤患者骨破坏的关系
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.1.94
Lina Lasminingrum, Sally Mahdiani, Dina Riana
Background: Chronic suppurative otitis media (CSOM) with cholesteatoma is one of the most common chronic infections found in developing countries. Cholesteatoma will stimulate bone resorption from the epithelial and stromal cells resulting in cytokine and keratinocyte formation, as well as mastoid bone destruction. The Ki-67 found in the proliferating cell shows that this protein plays an important role as a cell division process marker. Objective: Analyzing the association of Ki-67 on bone destruction in CSOM with cholesteatoma. Method: Participants in this study were CSOM patients with cholesteatoma who underwent surgery. Participants were assessed for bone destruction based on CT scan examination and confirmed during surgery. Examination of Ki-67 levels was carried out by taking cholesteatoma tissue at the time of surgery and analyzed using the ELISA method. The results of the examination were analyzed using the Spearman's rank correlation, Pearson’s correlation and logistic regression with p < 0.05. Results: The value of Ki-67 levels at each degree of destruction was degree 1 of 0.301, degree 2 of 0.36 ± 0.34, degree 3 of 0.41 ± 0.07, degree 4 of 0.60 ± 0.85, degree 5 of 0.74 ± 0.12, and degree 6 equal to 0.90 (r = 0.906; p = 0.001). In addition, there was a significant relationship between symptoms duration on bone destruction (r = 0.913; p = 0.001) and levels of Ki-67 (r = 0.887; p < 0.001). The regression coefficient was 0.079 for the independent variable, bone destruction with p = 0.009, and the regression coefficient 0.024 for symptoms duration with p = 0.014. Conclusion: Increased Ki-67 level in cholesteatoma is associated with bone destruction degree in CSOM patients with cholesteatoma.
背景:慢性化脓性中耳炎合并胆脂瘤是发展中国家最常见的慢性感染之一。胆脂瘤会刺激上皮细胞和基质细胞的骨吸收,导致细胞因子和角质细胞的形成,以及乳突骨的破坏。在增殖细胞中发现的Ki-67表明该蛋白作为细胞分裂过程的标志物起着重要的作用。目的:分析Ki-67与CSOM骨破坏与胆脂瘤的关系。方法:本研究的参与者是接受手术治疗的CSOM胆脂瘤患者。参与者在CT扫描检查的基础上评估骨破坏,并在手术中确认。手术时取胆脂瘤组织检测Ki-67水平,ELISA法分析。检验结果采用Spearman秩相关、Pearson相关和logistic回归分析,p < 0.05。结果:各破坏程度Ki-67值分别为1级0.301、2级0.36±0.34、3级0.41±0.07、4级0.60±0.85、5级0.74±0.12、6级0.90 (r = 0.906;P = 0.001)。此外,症状持续时间与骨破坏之间存在显著相关(r = 0.913;p = 0.001)和Ki-67水平(r = 0.887;P < 0.001)。自变量骨破坏的回归系数为0.079,p = 0.009;症状持续时间的回归系数为0.024,p = 0.014。结论:CSOM合并胆脂瘤患者胆脂瘤组织中Ki-67水平升高与骨破坏程度相关。
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引用次数: 2
Microelements in Soils and Cenopopulation of Medicinal Plants 土壤微量元素与药用植物种群
Pub Date : 2021-01-01 DOI: 10.51268/SRP.2021.4.8
Avazbek Turdalievich Turdaliev, Murodjon Isagaliev Tuychibaevich, Obidov Muzaffar Valijonovich, Yuldashev Gulom, Tukhtabaev Jamshid Sharafetdinovich, Doniyorbek Mamadaliyev
The article provides an analysis of the cenopopulation and element composition of the medicinal Capparis spinosa L. distributed in calcisols formed on eroded alluvial- proluvial rock-gravel rocks in the south of the Fergana Valley. The predominance of immature plants in the cenopopulation was detected in the Arsif hills, and quantitative indicators of micronutrients in the vegetative and generative organs of Capparis spinosa L. were determined. The study of biomorphological characteristics of the plant during the growing season (April-October) was carried out in the identified 10 observational experimental field populations. Soil, plant element analysis was performed by neutron-activation method. In this case, the samples were irradiated in a nuclear reactor with a neutron flux of 5 × 1013 neutrons/cm2sec, and their quantities were determined in accordance with the half-life of chemical elements. It has also been compared with research materials conducted by world scientists on the importance and pharmacological properties of botanicals in medicine and the food industry, as well as their botanical characteristics.
本文分析了费尔干纳河谷南部冲积-洪积-砾石侵蚀形成的钙质中分布的药用刺花的种群数量和元素组成。测定了紫荆山种群中未成熟植株的优势,测定了紫荆营养器官和生殖器官中微量元素的定量指标。在确定的10个观察性试验田群体中,研究了该植物生长季节(4 - 10月)的生物形态学特征。采用中子活化法对土壤、植物元素进行分析。在这种情况下,样品在核反应堆中以5 × 1013中子/cm2sec的中子通量照射,并根据化学元素的半衰期确定其数量。它还与世界科学家就植物药在医药和食品工业中的重要性和药理学特性及其植物学特征进行的研究材料进行了比较。
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引用次数: 0
Stabilizing 30ppm Iodine in Iodized Salt: The Effect on Iodine Status and Thyroid Function in Children 稳定碘盐中30ppm碘:对儿童碘状态和甲状腺功能的影响
Pub Date : 2021-01-01 DOI: 10.31838/SRP.2021.3.100
Leny Latifah, Suryati Kumorowulan, Y. Nurcahyani
Background: Salt iodization considers an effective way of ensuring iodine sufficiency, but a wide variation range of household salt iodine levels existed. Research in iodized salt intervention on preschool-age children had not been found. Objective: Analyse the effect of stabilizing 30 ppm household iodized salt for six months on iodine nutrition status and thyroid function. Method: This was a pre post-test experiment study, with 76 preschool-age children in a replete iodine area in Purworejo Regency. Iodized salt at 30ppm was given for six months. Thyroid function (TSH and FT4) were assessed at 0 and 6 months. Iodine status (UIE) were assessed at 0, 3, and 6 months. ANOVA RM mixed methods were used to interpret the result. Results: Before the study, 51.9% of households had an inadequate level of iodized salt. There were a significant increase of TSH (t=-3.184; p
背景:食盐加碘被认为是保证碘充足的一种有效方法,但家庭食盐碘水平存在较大差异。对学龄前儿童加碘盐干预的研究尚未见报道。目的:分析30 ppm家庭碘盐稳定6个月对碘营养状况和甲状腺功能的影响。方法:对普沃雷霍县碘含量高的地区的76名学龄前儿童进行前-后实验研究。30ppm的碘盐连续服用6个月。在0和6个月时评估甲状腺功能(TSH和FT4)。在0、3和6个月时评估碘状态(UIE)。采用方差分析、RM混合方法对结果进行解释。结果:研究前,51.9%的家庭碘盐摄入不足。TSH显著升高(t=-3.184;p
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引用次数: 0
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Systematic Reviews in Pharmacy
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