Aripiprazole (generic) — Abilify (brand)
Aripiprazole (generic) — Abilify (brand)
A nationwide cohort study conducted in Taiwan has found that lipid-modifying agents, particularly statins and fibrates, reduce mortality risk in patients with schizophrenia. The reduced risk was apparent for both all-cause and natural-cause mortality, the investigators reported. Study results were published online May 16, 2024, in The British Journal of Psychiatry.
Despite intensified warnings from regulators about fetal risk associated with the use of valproic acid during pregnancy, pregnancy incidence rates in women receiving valproic acid have remained largely unchanged, results of a cohort study suggest. Use of contraception in this population has also remained low overall, the investigators reported. Study results were published May 22, 2024, in JAMA Network Open.
Groups of patients who did not achieve abstinence from smoking after initial treatment with varenicline or nicotine replacement therapy saw improved results with subsequent strategies involving varenicline, a randomized trial has found. Nonabstainers who had received varenicline in the initial treatment phase benefited from a dosage increase in the follow-up phase.
Opioid analgesics such as codeine, hydrocodone, and tramadol undergo metabolism that is mediated by the polymorphic CYP2D6 isoenzyme, and research has shown that a CYP2D6 genotype-guided approach to pain control can optimize effectiveness and/or minimize adverse drug reactions associated with these analgesics in patients with different CYP2D6 genotypes (Smith et al., 2019).
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：