Lithium (generic) — Eskalith, Eskalith CR, Lithobid (brand)
Lithium (generic) — Eskalith, Eskalith CR, Lithobid (brand)
A 5-week trial has found that the combination of the muscarinic receptor agonist xanomeline and the peripheral muscarinic antagonist trospium significantly reduced symptoms of schizophrenia in adults. The xanomeline-trospium combination was well-tolerated, with no significant difference from placebo in extrapyramidal symptoms or weight gain.
Drug-induced movement disorders, including drug-induced parkinsonism, dystonia, akathisia, and tardive dyskinesia, are common adverse effects of dopamine receptor blockers, such as antipsychotics (especially first-generation agents). Anticholinergic medications are commonly used to treat extrapyramidal symptoms and drug-induced movement disorders. However, the multiple etiologies of the various types of abnormal movement disorders suggest that even though their presenting symptoms might be similar, different drug-induced movement disorders should not be treated with the same medication.
Women with prenatal depressive symptoms who received a single low dose of esketamine shortly after childbirth showed a substantially lower incidence of a major depressive episode at 42 days postpartum than women receiving placebo, a new study has found. Neuropsychiatric adverse events occurred more frequently in the esketamine group, but no severe adverse events were reported.
Children and adults with attention-deficit hyperactivity disorder (ADHD) who initiated medication treatment had significantly lower 2-year mortality rates compared with ADHD patients who did not initiate medication, a cohort study has found. The difference in mortality rates was greater for deaths due to unnatural causes such as accidental poisoning and suicide.
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