Objectives: Greater trochanteric pain syndrome (GTPS) is one of the causes of lateral hip pain. We aimed to determine the significance of certain anatomical parameters related to GTPS in imaging tests. Methods: Data of patients who were treated with glucocorticoid injection for trochanteric bursitis in our clinic between July 2019 and July 2022 for GTPS were analyzed. The control group was constituted of patients without GTPS but with hip and spinal problems who had pelvic computerized tomography (CT) images and undergone robotic-assisted knee arthroplasty. Standard anteroposterior pelvic radiograms, pelvic CTs, or magnetic resonance images were evaluated for anatomical parameters. Results: Among anatomical parameters, acetabular anteversion, length of trochanter major, and abductor index were significantly different between the patients with and without GTPS. Although mean age was different between the GTPS and control patient groups, age was not found to be correlated with any anatomical parameter. Abductor lever arm length (p = 0.001) and abductor index (p = 0.009) were found to be correlated. Conclusions: The length of trochanter major and abductor index were shown to be predisposing anatomical parameters for GTPS.
{"title":"Evaluation of radiologic predisposing factors for greater trochanteric pain syndrome","authors":"E. Şahin, A. Tanriöver","doi":"10.18621/eurj.1284544","DOIUrl":"https://doi.org/10.18621/eurj.1284544","url":null,"abstract":"Objectives: Greater trochanteric pain syndrome (GTPS) is one of the causes of lateral hip pain. We aimed to determine the significance of certain anatomical parameters related to GTPS in imaging tests. \u0000Methods: Data of patients who were treated with glucocorticoid injection for trochanteric bursitis in our clinic between July 2019 and July 2022 for GTPS were analyzed. The control group was constituted of patients without GTPS but with hip and spinal problems who had pelvic computerized tomography (CT) images and undergone robotic-assisted knee arthroplasty. Standard anteroposterior pelvic radiograms, pelvic CTs, or magnetic resonance images were evaluated for anatomical parameters.\u0000Results: Among anatomical parameters, acetabular anteversion, length of trochanter major, and abductor index were significantly different between the patients with and without GTPS. Although mean age was different between the GTPS and control patient groups, age was not found to be correlated with any anatomical parameter. Abductor lever arm length (p = 0.001) and abductor index (p = 0.009) were found to be correlated.\u0000Conclusions: The length of trochanter major and abductor index were shown to be predisposing anatomical parameters for GTPS.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"214 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79539279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Tunç, D. Yalınbaş Yeter, Feyzanur Karagöz, Emine Erva Tecer, S. Akkan, F. Kılıçbay
Objectives: This study aimed to examine whether infants with and without eye patches differ in terms of vital signs and clinical status after retinopathy of prematurity examination. Methods: Premature infants hospitalized in study center between June 2021-April 2022 were included. Group 1 is consisted of infants whose eyes were not closed after retinopathy of prematurity examination. Those infants whose eyes were closed eye-patches consisted of group 2. Vital signs were followed for 24 hours following the examination. Demographic, medical and follow-up data were all recorded prospectively. Vital signs were evaluated in accordance with birth week and weight. Pain score was evaluated by Neonatal Pain, Agitation, and Sedation Scale. Results: Pain scores were found to be lower in group 2 (p < 0.020). Although the systolic blood pressure, diastolic blood pressure, and mean blood pressure values of group 2 were found to be lower than group 1, they were within normal limits (all p < 0.05). Vomiting was not observed at all in Group 1 (p = 0.036). There was no significant difference between the groups in terms of fever, respiratory rate, heart rate, SpO2, and blood glucose values. Conclusions: This study showed that using an eye patch in infants after an eye examination reduces pain and increases comfort of infants. Although their pain scores are lower, taking necessary precautions are recommended for these patients in terms of vomiting. Thus, eye patches can be suggested as a non-pharmacological pain-reducing method after get advanced stagnation by the support of more studies with a larger number of participants.
{"title":"The possible effect of light exposure reduction via eye patches after the examination for retinopathy in premature infants? An observational study in preterm neonates","authors":"G. Tunç, D. Yalınbaş Yeter, Feyzanur Karagöz, Emine Erva Tecer, S. Akkan, F. Kılıçbay","doi":"10.18621/eurj.1273038","DOIUrl":"https://doi.org/10.18621/eurj.1273038","url":null,"abstract":"Objectives: This study aimed to examine whether infants with and without eye patches differ in terms of vital signs and clinical status after retinopathy of prematurity examination.\u0000Methods: Premature infants hospitalized in study center between June 2021-April 2022 were included. Group 1 is consisted of infants whose eyes were not closed after retinopathy of prematurity examination. Those infants whose eyes were closed eye-patches consisted of group 2. Vital signs were followed for 24 hours following the examination. Demographic, medical and follow-up data were all recorded prospectively. Vital signs were evaluated in accordance with birth week and weight. Pain score was evaluated by Neonatal Pain, Agitation, and Sedation Scale. \u0000Results: Pain scores were found to be lower in group 2 (p < 0.020). Although the systolic blood pressure, diastolic blood pressure, and mean blood pressure values of group 2 were found to be lower than group 1, they were within normal limits (all p < 0.05). Vomiting was not observed at all in Group 1 (p = 0.036). There was no significant difference between the groups in terms of fever, respiratory rate, heart rate, SpO2, and blood glucose values.\u0000Conclusions: This study showed that using an eye patch in infants after an eye examination reduces pain and increases comfort of infants. Although their pain scores are lower, taking necessary precautions are recommended for these patients in terms of vomiting. Thus, eye patches can be suggested as a non-pharmacological pain-reducing method after get advanced stagnation by the support of more studies with a larger number of participants.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82093024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study aimed to determine post-traumatic growth and its predictors in female relatives of patients with methamphetamine use disorder. Methods: The volunteers in our study consisted of 80 adult women who were first-degree relatives of male patients diagnosed with MUD. The Post-Traumatic Growth Inventory, the Hospital Anxiety-Depression Scale, the Impact of Events Scale , and the short form of the Coping with Stressful Situations Inventory were given to the relatives of the patients. Results: In our study, being employed and being married were found to affect task-oriented coping and changes in self-perception positively. Task-oriented coping or seeking emotional support from others predicted higher PTG. Task-oriented coping was positively associated with emotional coping and a change in the philosophy of life. The regression analysis determined that task-oriented and avoidant coping mechanisms were the best predictors of post-traumatic growth. Conclusions: The findings suggest that environmental and personal factors, such as being married, being employed, and the quality of social relationships that emerge with emotional and instrumental support, influence the experience of life crises. In addition, the duration of methamphetamine uses, the problem's, and the search for solutions were all associated with higher post-traumatic growth. Thus, the results of this study demonstrate that task-oriented coping, seeking emotional support, and the duration of methamphetamine use may contribute to post-traumatic growth.
{"title":"Posttraumatic growth in family members of individuals with methamphetamine use disorder","authors":"Ç. Turan, S. Ünal, G. Şenormancı, Ömer Şenormancı","doi":"10.18621/eurj.1276458","DOIUrl":"https://doi.org/10.18621/eurj.1276458","url":null,"abstract":"Objectives: This study aimed to determine post-traumatic growth and its predictors in female relatives of patients with methamphetamine use disorder. \u0000Methods: The volunteers in our study consisted of 80 adult women who were first-degree relatives of male patients diagnosed with MUD. The Post-Traumatic Growth Inventory, the Hospital Anxiety-Depression Scale, the Impact of Events Scale , and the short form of the Coping with Stressful Situations Inventory were given to the relatives of the patients. \u0000Results: In our study, being employed and being married were found to affect task-oriented coping and changes in self-perception positively. Task-oriented coping or seeking emotional support from others predicted higher PTG. Task-oriented coping was positively associated with emotional coping and a change in the philosophy of life. The regression analysis determined that task-oriented and avoidant coping mechanisms were the best predictors of post-traumatic growth. \u0000Conclusions: The findings suggest that environmental and personal factors, such as being married, being employed, and the quality of social relationships that emerge with emotional and instrumental support, influence the experience of life crises. In addition, the duration of methamphetamine uses, the problem's, and the search for solutions were all associated with higher post-traumatic growth. Thus, the results of this study demonstrate that task-oriented coping, seeking emotional support, and the duration of methamphetamine use may contribute to post-traumatic growth.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"os-10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87029638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: In patients with acute coronary syndrome, age, ejection fraction, diabetes, hypertension, and chronic kidney disease (CKD) are regarded as independent risk factors for the development of acute kidney disease (ACD). This research evaluated the glomerular filtration rates (GFR) of acute coronary syndrome patient groups who were hypertensive and those who were not. Methods: This retrospective analysis comprised 764 patients with acute coronary syndrome who had applied to our institution before coronary angiography. There were two groups created from these patients. In the first group, there were 383 hypertensive patients; in the second group, there were 381 non-hypertensive patients. To assess how well these patients' kidneys were functioning, GFR was determined and compared. Results: The mean age of the two groups did not significantly differ from one another (p = 0.053). The standard lipid measures of total cholesterol, triglyceride, low-density lipoprotein-cholesterol, and high-density lipoprotein-cholesterol levels did not differ substantially between the two groups. The two groups had no discernible difference regarding high-sensitivity C-reactive protein, N-terminal fragment brain natriuretic peptides, creatinine, and thrombocyte levels. Systolic and diastolic blood pressure, as well as diabetes mellitus, were all considerably higher in the hypertensive patients’ group (p < 0.001). The GFR in hypertensive patients was substantially lower (64.83 ± 19.76 vs. 70.71 ± 19.19, p < 0.001) Conclusions: Our research revealed a strong link between hypertension and diminished renal function. This leads us to believe that hypertension may be a separate risk factor for the decline in renal function in acute coronary syndrome patients.
目的:在急性冠状动脉综合征患者中，年龄、射血分数、糖尿病、高血压和慢性肾脏疾病(CKD)被认为是急性肾脏疾病(ACD)发展的独立危险因素。本研究对急性冠脉综合征高血压组和非高血压组的肾小球滤过率(GFR)进行了评价。方法:回顾性分析764例冠脉造影前到我院就诊的急性冠脉综合征患者。这些病人被分成了两组。第一组高血压患者383例;第二组有381例非高血压患者。为了评估这些患者的肾脏功能，测定并比较GFR。结果:两组患者平均年龄差异无统计学意义(p = 0.053)。总胆固醇、甘油三酯、低密度脂蛋白-胆固醇和高密度脂蛋白-胆固醇水平的标准脂质测量在两组之间没有显著差异。两组在高灵敏度c反应蛋白、n端脑钠肽片段、肌酐和血小板水平方面没有明显差异。高血压组的收缩压和舒张压以及糖尿病均明显升高(p < 0.001)。高血压患者的GFR显著降低(64.83±19.76 vs. 70.71±19.19,p < 0.001)结论:我们的研究揭示了高血压与肾功能下降之间的密切联系。这使我们相信高血压可能是急性冠状动脉综合征患者肾功能下降的一个单独的危险因素。
{"title":"The effect of hypertension on renal functions in patients with acute coronary syndrome","authors":"Umut Uyan","doi":"10.18621/eurj.1249547","DOIUrl":"https://doi.org/10.18621/eurj.1249547","url":null,"abstract":"Objectives: In patients with acute coronary syndrome, age, ejection fraction, diabetes, hypertension, and chronic kidney disease (CKD) are regarded as independent risk factors for the development of acute kidney disease (ACD). This research evaluated the glomerular filtration rates (GFR) of acute coronary syndrome patient groups who were hypertensive and those who were not.\u0000Methods: This retrospective analysis comprised 764 patients with acute coronary syndrome who had applied to our institution before coronary angiography. There were two groups created from these patients. In the first group, there were 383 hypertensive patients; in the second group, there were 381 non-hypertensive patients. To assess how well these patients' kidneys were functioning, GFR was determined and compared.\u0000Results: The mean age of the two groups did not significantly differ from one another (p = 0.053). The standard lipid measures of total cholesterol, triglyceride, low-density lipoprotein-cholesterol, and high-density lipoprotein-cholesterol levels did not differ substantially between the two groups. The two groups had no discernible difference regarding high-sensitivity C-reactive protein, N-terminal fragment brain natriuretic peptides, creatinine, and thrombocyte levels. Systolic and diastolic blood pressure, as well as diabetes mellitus, were all considerably higher in the hypertensive patients’ group (p < 0.001). The GFR in hypertensive patients was substantially lower (64.83 ± 19.76 vs. 70.71 ± 19.19, p < 0.001)\u0000Conclusions: Our research revealed a strong link between hypertension and diminished renal function. This leads us to believe that hypertension may be a separate risk factor for the decline in renal function in acute coronary syndrome patients.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82375475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study was conducted to conduct a systematic review and meta-analysis of studies examining the effect of aromatherapy intervention on labor pain, duration of labor, anxiety and apgar scores in primiparous women. Methods: The literature search was conducted in PubMed, CINAHL, Scopus and Science Citation Index (Web of Science) until February 2023. This study is based on the recommendations of the Cochrane guidelines. The data were analyzed using the Review Manager computer program (Version 5.4). Results: The analysis was completed with 10 studies including 950 primiparous pregnant women. The average pooled results of the studies showed that there was a significant difference in the effect of aromatherapy on labor pain (SMD: -0.68 95% CI: -0.76 to -0.60, Z = 16.32, p < 0.01) and duration (SMD: -0.36 95% CI: -0.47 to -0.25, Z = 6.40, p < 0.00001) in the latent, active, and transition phase. When the mean results of anxiety scores were examined, it was determined that the difference between the groups was significant (SMD: -15.89 95% CI: -16.78 to -14.99, Z = 34.79, p < 0.00001). Conclusions: While the aromatherapy application used in childbirth reduced the duration and pain of the latent transition and active phase of birth, it was found that it reduced the anxiety of the pregnants in the active and transition phase.
目的:本研究旨在对芳香疗法干预对初产妇分娩疼痛、分娩持续时间、焦虑和apgar评分的影响进行系统回顾和荟萃分析。方法:截至2023年2月，在PubMed、CINAHL、Scopus和Science Citation Index (Web of Science)中进行文献检索。这项研究是基于Cochrane指南的建议。使用Review Manager计算机程序(Version 5.4)对数据进行分析。结果:共纳入10项研究，包括950例初产妇。这些研究的平均汇总结果显示，芳香疗法对潜伏期、活跃期和过渡期分娩疼痛(SMD: -0.68 95% CI: -0.76 ~ -0.60, Z = 16.32, p < 0.01)和持续时间(SMD: -0.36 95% CI: -0.47 ~ -0.25, Z = 6.40, p < 0.00001)的影响有显著差异。当检查焦虑得分的平均结果时，确定组间差异有统计学意义(SMD: -15.89 95% CI: -16.78 ~ -14.99, Z = 34.79, p < 0.00001)。结论:芳香疗法应用于分娩，在减少分娩潜伏过渡期和活跃期的持续时间和疼痛的同时，发现它减少了妊娠活跃期和活跃期的焦虑。
{"title":"The effect of aromatherapy on labor pain, duration of labor, anxiety and Apgar score outcome: a systematic review and meta-analysis","authors":"A. YILDIZ KARAAHMET, Fatma Sule Bilgic","doi":"10.18621/eurj.1261999","DOIUrl":"https://doi.org/10.18621/eurj.1261999","url":null,"abstract":"Objectives: This study was conducted to conduct a systematic review and meta-analysis of studies examining the effect of aromatherapy intervention on labor pain, duration of labor, anxiety and apgar scores in primiparous women.\u0000Methods: The literature search was conducted in PubMed, CINAHL, Scopus and Science Citation Index (Web of Science) until February 2023. This study is based on the recommendations of the Cochrane guidelines. The data were analyzed using the Review Manager computer program (Version 5.4).\u0000Results: The analysis was completed with 10 studies including 950 primiparous pregnant women. The average pooled results of the studies showed that there was a significant difference in the effect of aromatherapy on labor pain (SMD: -0.68 95% CI: -0.76 to -0.60, Z = 16.32, p < 0.01) and duration (SMD: -0.36 95% CI: -0.47 to -0.25, Z = 6.40, p < 0.00001) in the latent, active, and transition phase. When the mean results of anxiety scores were examined, it was determined that the difference between the groups was significant (SMD: -15.89 95% CI: -16.78 to -14.99, Z = 34.79, p < 0.00001). \u0000Conclusions: While the aromatherapy application used in childbirth reduced the duration and pain of the latent transition and active phase of birth, it was found that it reduced the anxiety of the pregnants in the active and transition phase.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83922091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Kaplangoray, K. Toprak, C. Aydın, Ramazan Aslan
Objectives: No-reflow phenomenon (NRP) is a complication associated with poor clinical outcome in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). The modified Glasgow prognostic score (mGPS) is a novel immune-inflammatory index, derived from C-reactive protein (CRP) and serum albumin levels and has been shown to be associated with prognosis in heart disease. In this study we aimed to investigated the relationship between mGPS and NRP in patients undergoing pPCI for STEMI. Methods: A total of 379 patients (aged 59 ± 9.9 years; 54.9% male) were enrollled. The patients were divided into 2 groups:no-reflow (n = 72) and reflow (n = 307). No-reflow was defined as thrombolysis in myocardial infarction (TIMI) ≤ 2 flow. The mGPS of all patients was calculated from blood samples at admission. Logistic regression analysis was performed to determine the independent predictive factors for NRP. Results: Mean age, pain to balloon duration, troponin T, white blood cell (WBC), Syntax score, neutrophil to lymphocyte ratio (NLR), glucose level, C-reactive protein level (CRP), diabetic and female patient ratio were higher, while left ventricular ejection fraction, ST segment resolution ratio at 60 min, and serum albumin level were lower in the NRP group.Logistic regression analysis showed that WBC count [Hazard ratio (HR): 0.816, 95% confidence interval (CI): 0.728-0.914, p < 0.001], NLR (HR: 0.482, CI: 0.355-0.654, p < 0.001), pain-to-balloon time (HR: 0.976, CI:0.960-0.991, p = 0.002) and mGPS (HR: 3.213, CI: 1.643- 6.283, p = 0.001) were independent predictive factors for NRP. Conclusions: Modified GPS is an independent predictive factor for NRP in patients undergoing pPCI for STEMI.
目的:无血流再流现象(NRP)是st段抬高型心肌梗死(STEMI)患者接受原发性经皮冠状动脉介入治疗(pPCI)时临床预后较差的并发症。改良格拉斯哥预后评分(mGPS)是一种新的免疫炎症指数，来源于c反应蛋白(CRP)和血清白蛋白水平，已被证明与心脏病的预后相关。在本研究中，我们旨在探讨STEMI pPCI患者的mGPS和NRP之间的关系。方法:共379例患者(年龄59±9.9岁;(54.9%为男性)。患者分为2组:非回流组(72例)和回流组(307例)。无回流定义为心肌梗死溶栓(TIMI)≤2血流。所有患者的mGPS均由入院时的血液样本计算。采用Logistic回归分析确定NRP的独立预测因素。结果:NRP组患者的平均年龄、疼痛至球囊持续时间、肌钙蛋白T、白细胞(WBC)、Syntax评分、中性粒细胞/淋巴细胞比(NLR)、血糖水平、c反应蛋白水平(CRP)、糖尿病患者及女性患者比例较高，左室射血分数、60 min ST段分辨率、血清白蛋白水平较低。Logistic回归分析显示，WBC计数[危险比(HR): 0.816, 95%可信区间(CI): 0.728 ~ 0.914, p < 0.001]、NLR (HR: 0.482, CI: 0.355 ~ 0.654, p < 0.001)、疼痛至球囊时间(HR: 0.976, CI:0.960 ~ 0.991, p = 0.002)和mGPS (HR: 3.213, CI: 1.643 ~ 6.283, p = 0.001)是NRP的独立预测因素。结论:改良GPS是STEMI行pPCI患者NRP的独立预测因素。
{"title":"Investigation of the relationship between modified Glasgow prognostic score and no-reflow phenomenon in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction","authors":"Mustafa Kaplangoray, K. Toprak, C. Aydın, Ramazan Aslan","doi":"10.18621/eurj.1284893","DOIUrl":"https://doi.org/10.18621/eurj.1284893","url":null,"abstract":"Objectives: No-reflow phenomenon (NRP) is a complication associated with poor clinical outcome in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). The modified Glasgow prognostic score (mGPS) is a novel immune-inflammatory index, derived from C-reactive protein (CRP) and serum albumin levels and has been shown to be associated with prognosis in heart disease. In this study we aimed to investigated the relationship between mGPS and NRP in patients undergoing pPCI for STEMI.\u0000Methods: A total of 379 patients (aged 59 ± 9.9 years; 54.9% male) were enrollled. The patients were divided into 2 groups:no-reflow (n = 72) and reflow (n = 307). No-reflow was defined as thrombolysis in myocardial infarction (TIMI) ≤ 2 flow. The mGPS of all patients was calculated from blood samples at admission. Logistic regression analysis was performed to determine the independent predictive factors for NRP.\u0000Results: Mean age, pain to balloon duration, troponin T, white blood cell (WBC), Syntax score, neutrophil to lymphocyte ratio (NLR), glucose level, C-reactive protein level (CRP), diabetic and female patient ratio were higher, while left ventricular ejection fraction, ST segment resolution ratio at 60 min, and serum albumin level were lower in the NRP group.Logistic regression analysis showed that WBC count [Hazard ratio (HR): 0.816, 95% confidence interval (CI): 0.728-0.914, p < 0.001], NLR (HR: 0.482, CI: 0.355-0.654, p < 0.001), pain-to-balloon time (HR: 0.976, CI:0.960-0.991, p = 0.002) and mGPS (HR: 3.213, CI: 1.643- 6.283, p = 0.001) were independent predictive factors for NRP. \u0000Conclusions: Modified GPS is an independent predictive factor for NRP in patients undergoing pPCI for STEMI.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86583806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salma AL KHANJARİ, Malak Saleem AL BALUSHİ, R. Kanojia, Mohammed Jaffer AL SAJWANİ
Diagnosing, managing and assigning gender for different causes of ambiguous genitalia in children can be challenging. This article will discuss about the types, diagnosis and treatment of disorders of sex development including congenital adrenal hyperplasia, 46 XY mixed gonadal dysgenesis and 46XY ovotesticular disorder of sex development. This article reports about 3 cases of disorders of sex development. The first case is about a three-year-old girl who was diagnosed with congenital adrenal hyperplasia, genital examination revealed clitoromegaly and a single urogenital sinus; she was managed medically and surgically. The second case is about a one-month-old child with 46XY karyotype, genital examination revealed penoscrotal hypospadias with right palpable and left impalpable gonads. Patient underwent diagnostic laparoscopy in which both female and male internal organs were found; based on these results a diagnosis of 46XY ovotesticular disorder of sex development was made. The third case is about a 3-month-old child with 46XY karyotype, genital examination revealed hypospadias with bilateral impalpable gonads. Diagnostic laparoscopy showed a uterus with a bilateral ovary-looking gonad; histopathology of the bilateral ovary-looking gonads was consistent with testicular tissue. Based on the above, a diagnosis of 46XY mixed gonadal dysgenesis was made. Disorders of sex development are classified into three main categories based on the karyotype, XX, XY and sex chromosome other than XX and XY. Laboratory investigations, karyotype, genetic analysis, imaging, surgery and tissue biopsy, all aid in diagnosing, deciding gender identity and managing different types of disorders of sex development.
{"title":"''Should the child be raised as male or female?'' The evaluation and management of different causes of ambiguous genital appearance in children","authors":"Salma AL KHANJARİ, Malak Saleem AL BALUSHİ, R. Kanojia, Mohammed Jaffer AL SAJWANİ","doi":"10.18621/eurj.1285835","DOIUrl":"https://doi.org/10.18621/eurj.1285835","url":null,"abstract":"Diagnosing, managing and assigning gender for different causes of ambiguous genitalia in children can be challenging. This article will discuss about the types, diagnosis and treatment of disorders of sex development including congenital adrenal hyperplasia, 46 XY mixed gonadal dysgenesis and 46XY ovotesticular disorder of sex development. This article reports about 3 cases of disorders of sex development. The first case is about a three-year-old girl who was diagnosed with congenital adrenal hyperplasia, genital examination revealed clitoromegaly and a single urogenital sinus; she was managed medically and surgically. The second case is about a one-month-old child with 46XY karyotype, genital examination revealed penoscrotal hypospadias with right palpable and left impalpable gonads. Patient underwent diagnostic laparoscopy in which both female and male internal organs were found; based on these results a diagnosis of 46XY ovotesticular disorder of sex development was made. The third case is about a 3-month-old child with 46XY karyotype, genital examination revealed hypospadias with bilateral impalpable gonads. Diagnostic laparoscopy showed a uterus with a bilateral ovary-looking gonad; histopathology of the bilateral ovary-looking gonads was consistent with testicular tissue. Based on the above, a diagnosis of 46XY mixed gonadal dysgenesis was made. Disorders of sex development are classified into three main categories based on the karyotype, XX, XY and sex chromosome other than XX and XY. Laboratory investigations, karyotype, genetic analysis, imaging, surgery and tissue biopsy, all aid in diagnosing, deciding gender identity and managing different types of disorders of sex development.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85883167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Methemoglobinemia is a serious hematological disease characterized by the incapability of sufficient oxygen delivery to tissues and cyanosis when iron within hemoglobin in ferrous form (Fe+2) is oxidized to ferric form (Fe+3). Methemoglobinemia may be congenital or acquired. While prilocaine-induced methemoglobinemia can be seen in newborns and early pediatric ages, it is a rare condition in adults. We aimed to investigate prilocaine-induced adult methemoglobinemia with four cases.
{"title":"Methemoglobinemia after local anesthesia with prilocaine in adults: four case reports","authors":"M. Yilmaz, Arif İşcan, L. Mutlu","doi":"10.18621/eurj.1208264","DOIUrl":"https://doi.org/10.18621/eurj.1208264","url":null,"abstract":"Methemoglobinemia is a serious hematological disease characterized by the incapability of sufficient oxygen delivery to tissues and cyanosis when iron within hemoglobin in ferrous form (Fe+2) is oxidized to ferric form (Fe+3). Methemoglobinemia may be congenital or acquired. While prilocaine-induced methemoglobinemia can be seen in newborns and early pediatric ages, it is a rare condition in adults. We aimed to investigate prilocaine-induced adult methemoglobinemia with four cases.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90939838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Demir, Mehmet Ak, Şeyma DAĞLITUNCEZDİ ÇAM, Cevat Rifat Cündübey
Objectives: The present study attempted to evaluate the relationship between fetal growth restriction (FGR) and the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in singleton term pregnancy. Methods: We carried out this prospective, case-control study at a Training and Research Hospital in Türkiye between May 2021 and January 2023. We utilized ultrasonography to assess singleton pregnancy with FGR between 37-40 weeks of gestation and considered the patients’ last menstrual periods (LMD). Results: We recruited 250 pregnant women in the study and divided them into the FGR (n = 125) and healthy control (n = 125) groups. Our findings revealed no significant difference between the groups by age, body mass index (BMI), stillbirth history, abortion, tobacco use, and regular pregnancy monitoring (p > 0.05). Fetal birth weights and hospitalization in the neonatal intensive care unit (NICU) were also similar between the groups. Yet, 1- and 5-minute APGAR scores were significantly lower in the FGR group than in the control group. In addition, compared to the healthy subjects, the FGR group had significantly increased white blood cell, lymphocyte, neutrophil, platelet counts and NLR and PLR values, but mean platelet volume (MPV) remained similar. Conclusions: In a nutshell, our findings suggested that two noteworthy inflammatory markers, NLR and PLR, are likely to elevate in the presence of FGR.
{"title":"Evaluation of umbilical cord blood hematological parameters in pregnant women with fetal growth restriction","authors":"M. Demir, Mehmet Ak, Şeyma DAĞLITUNCEZDİ ÇAM, Cevat Rifat Cündübey","doi":"10.18621/eurj.1265286","DOIUrl":"https://doi.org/10.18621/eurj.1265286","url":null,"abstract":"Objectives: The present study attempted to evaluate the relationship between fetal growth restriction (FGR) and the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in singleton term pregnancy.\u0000Methods: We carried out this prospective, case-control study at a Training and Research Hospital in Türkiye between May 2021 and January 2023. We utilized ultrasonography to assess singleton pregnancy with FGR between 37-40 weeks of gestation and considered the patients’ last menstrual periods (LMD). \u0000Results: We recruited 250 pregnant women in the study and divided them into the FGR (n = 125) and healthy control (n = 125) groups. Our findings revealed no significant difference between the groups by age, body mass index (BMI), stillbirth history, abortion, tobacco use, and regular pregnancy monitoring (p > 0.05). Fetal birth weights and hospitalization in the neonatal intensive care unit (NICU) were also similar between the groups. Yet, 1- and 5-minute APGAR scores were significantly lower in the FGR group than in the control group. In addition, compared to the healthy subjects, the FGR group had significantly increased white blood cell, lymphocyte, neutrophil, platelet counts and NLR and PLR values, but mean platelet volume (MPV) remained similar.\u0000Conclusions: In a nutshell, our findings suggested that two noteworthy inflammatory markers, NLR and PLR, are likely to elevate in the presence of FGR.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87028664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The aim of this study was to compare serum uric acid levels in patients with methamphetamine and synthetic cannabinoid use disorders pre- and post-detoxification treatment with healthy controls. Secondly, to determine the relationship between the serum uric acid levels of the cases and the severity of the addiction. Methods: Fifty methamphetamine, 50 synthetic cannabinoids, and 40 healthy controls were evaluated on the specified dates. Venous blood samples were taken from the participants to measure serum uric acid and creatinine levels. The arrangement was made by taking the Uric acid/creatinine ratio to neutralize the confounding effect of kidney functions. The Addiction Profile Index was applied to determine the severity of substance abuse in the case group. Results: A statistically significant difference was found between the uric acid values of all three groups when the One-way ANOVA test was performed (p < 0.001). UA values were significantly lower in the case groups than in the healthy control group. When the substance use characteristics of the case groups were compared, a statistically significant difference was found in the duration of substance use (p < 0.010) and motivation (p = 0.031) subtests. Duration of substance use and craving were higher in the synthetic substance group, and motivation was higher in the methamphetamine group. According to the Pearson analysis, the severity of addiction was deduced not to be correlated with serum uric acid and uric acid/creatinine levels in both case groups. Conclusions: Serum uric acid and uric acid/creatinine levels were found to be statistically significantly lower in individuals with methamphetamine and synthetic cannabinoid exposure compared to healthy controls. In this study, it was thought that the lower uric acid levels in the case group compared to the control group may be due to the use of uric acid as an antioxidant or a decrease in purinergic transformation. Future studies may focus on making this distinction.
{"title":"The relationship between serum uric acid levels and severity of addiction in individuals with substance use disorders","authors":"Ç. Turan, S. Ünal","doi":"10.18621/eurj.1270126","DOIUrl":"https://doi.org/10.18621/eurj.1270126","url":null,"abstract":"Objectives: The aim of this study was to compare serum uric acid levels in patients with methamphetamine and synthetic cannabinoid use disorders pre- and post-detoxification treatment with healthy controls. Secondly, to determine the relationship between the serum uric acid levels of the cases and the severity of the addiction. \u0000Methods: Fifty methamphetamine, 50 synthetic cannabinoids, and 40 healthy controls were evaluated on the specified dates. Venous blood samples were taken from the participants to measure serum uric acid and creatinine levels. The arrangement was made by taking the Uric acid/creatinine ratio to neutralize the confounding effect of kidney functions. The Addiction Profile Index was applied to determine the severity of substance abuse in the case group. \u0000Results: A statistically significant difference was found between the uric acid values of all three groups when the One-way ANOVA test was performed (p < 0.001). UA values were significantly lower in the case groups than in the healthy control group. When the substance use characteristics of the case groups were compared, a statistically significant difference was found in the duration of substance use (p < 0.010) and motivation (p = 0.031) subtests. Duration of substance use and craving were higher in the synthetic substance group, and motivation was higher in the methamphetamine group. According to the Pearson analysis, the severity of addiction was deduced not to be correlated with serum uric acid and uric acid/creatinine levels in both case groups. \u0000Conclusions: Serum uric acid and uric acid/creatinine levels were found to be statistically significantly lower in individuals with methamphetamine and synthetic cannabinoid exposure compared to healthy controls. In this study, it was thought that the lower uric acid levels in the case group compared to the control group may be due to the use of uric acid as an antioxidant or a decrease in purinergic transformation. Future studies may focus on making this distinction.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84860619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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