F. Koca, F. Levent, A. As, Fatih Köksal, A. B. Tatlı, F. Vatansever, M. Demir, E. Tenekecioğlu
Objective: The aim of this study was to investigate whether there is subtle cardiac dysfunction in patients with chronic venous insufficiency. Methods: Age and sex matched 56 patients with a score of C3 and above in the Clinical, Etiological, Anatomical, Pathophysiological classification and 56 healthy volunteers were included in the study. All subjects were evaluated by detailed echocardiographic examination, including two-dimensional strain echocardiographic analysis by speckle tracking method. Results: Mitral E wave deceleration time (EDT), E and A wave velocity, E/e' ratio for left ventricle, tricuspid EDT, E/e’ ratio for right ventricle and systolic pulmonary artery pressure were found high as significant statistically in patients groups (p < 0.05). But no any statistically significant difference was observed in other parameters between two groups. Conclusions: There may be an increase in diastolic filling pressures in patients with chronic venous insufficiency due to the increased preload in the supine position. This condition seems to be clinically important in patients at high risk for heart failure due to the presumption of the early treatment of chronic venous insufficiency may reduce the risk of heart failure evolvement.
{"title":"Does chronic venous insufficiency affect cardiac functions? A speckle tracking echocardiography study","authors":"F. Koca, F. Levent, A. As, Fatih Köksal, A. B. Tatlı, F. Vatansever, M. Demir, E. Tenekecioğlu","doi":"10.18621/eurj.1286517","DOIUrl":"https://doi.org/10.18621/eurj.1286517","url":null,"abstract":"Objective: The aim of this study was to investigate whether there is subtle cardiac dysfunction in patients with chronic venous insufficiency.\u0000Methods: Age and sex matched 56 patients with a score of C3 and above in the Clinical, Etiological, Anatomical, Pathophysiological classification and 56 healthy volunteers were included in the study. All subjects were evaluated by detailed echocardiographic examination, including two-dimensional strain echocardiographic analysis by speckle tracking method. \u0000Results: Mitral E wave deceleration time (EDT), E and A wave velocity, E/e' ratio for left ventricle, tricuspid EDT, E/e’ ratio for right ventricle and systolic pulmonary artery pressure were found high as significant statistically in patients groups (p < 0.05). But no any statistically significant difference was observed in other parameters between two groups. \u0000Conclusions: There may be an increase in diastolic filling pressures in patients with chronic venous insufficiency due to the increased preload in the supine position. This condition seems to be clinically important in patients at high risk for heart failure due to the presumption of the early treatment of chronic venous insufficiency may reduce the risk of heart failure evolvement.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77950020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: In this study, it was investigated the effects of intensive aphasia treatment applied to individuals with non-fluent aphasia. Methods: Sixteen patients diagnosed with non-fluent aphasia were included in the study and were randomly divided into two groups. The therapy interventions were one day per week for the eight patients in the first group, for a total of 8 hours in 2 months (standard intervention). For the eight patients in the second group, therapy was applied for a total of 48 hours in 2 months, for one hour per day, six days a week, excluding Sundays (intensive intervention). Participants were tested using the Turkish aphasia test (ADD), Aphasia Impact Scale-21 (AIQ-21), and Boston Naming Test (BNT) before starting the treatment (pretest), after the treatment (posttest), and one month after the treatment ended (follow-up). Results: At the end of the treatments, a significant increase in ADD and BNT scores and a significant decrease in AIQ-21 scores were observed in both groups. Although there was a change in the follow-up test, the scores were still significantly different than the pretest scores. The rate of improvement in test scores of group II patients who received intensive aphasia treatment was superior to the group I patients. Conclusion: Intensive application was superior to once-weekly aphasia treatment, and post-treatment improvement continued for at least one month after the treatments.
{"title":"Is semantic feature analysis effective when applied intensively? A randomized pilot study with non-fluent aphasic individuals","authors":"İbrahim Can Yaşa","doi":"10.18621/eurj.1328853","DOIUrl":"https://doi.org/10.18621/eurj.1328853","url":null,"abstract":"Objective: In this study, it was investigated the effects of intensive aphasia treatment applied to individuals with non-fluent aphasia.\u0000Methods: Sixteen patients diagnosed with non-fluent aphasia were included in the study and were randomly divided into two groups. The therapy interventions were one day per week for the eight patients in the first group, for a total of 8 hours in 2 months (standard intervention). For the eight patients in the second group, therapy was applied for a total of 48 hours in 2 months, for one hour per day, six days a week, excluding Sundays (intensive intervention). Participants were tested using the Turkish aphasia test (ADD), Aphasia Impact Scale-21 (AIQ-21), and Boston Naming Test (BNT) before starting the treatment (pretest), after the treatment (posttest), and one month after the treatment ended (follow-up).\u0000Results: At the end of the treatments, a significant increase in ADD and BNT scores and a significant decrease in AIQ-21 scores were observed in both groups. Although there was a change in the follow-up test, the scores were still significantly different than the pretest scores. The rate of improvement in test scores of group II patients who received intensive aphasia treatment was superior to the group I patients. \u0000Conclusion: Intensive application was superior to once-weekly aphasia treatment, and post-treatment improvement continued for at least one month after the treatments.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"65 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90942888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Isthmocele is a hypoechoic area within the lower uterine segment myometrium, resulting from a discontinuation of the myometrium at the site of a previous cesarean scar. The aim of this study was to examine the influence of maternal cellular and inflammatory status prior to Cesarean Section (CS) on isthmocele formation. Methods: This prospective observational study was conducted in a tertiary hospital and included women with a history of one previous CS. The inflammatory and cellular parameters were collected and ultrasonographic examinations were conducted in the 6th postpartum month and then analyzed. Logistic regression analysis was performed to identify potential factors influencing isthmocele formation. Results: Of the 106 patients, 31 (29.2%) were diagnosed with isthmocele after one previous CS. There were no significant differences in terms of demographical variables between the groups. However, the duration of CS was significantly longer in the isthmocele group compared to the group without isthmocele (42.58 ± 8.77 vs. 38.42 ± 9.50 minutes, p = 0.03). The neutrophil-to-lymphocyte ratio (NLR) was higher and platelet-to-lymphocyte ratio (PLR) was lower in the isthmocele group (p < 0.001). Logistic regression analysis revealed that, NLR (OR [odds ratio]: 0.23, 95% CI [confidence interval]: 0.117- 0.473, p < 0.001) and PLR (OR: 1.05, 95% CI: 1.027-1.078, p < 0.001) were identified as independent predictors for isthmocele formation after planned CS. Conclusion: Inflammatory markers, such as NLR and PLR, may contribute to the formation of isthmocele in women with a history of one previous CS, shedding light on the underlying pathophysiology.
目的:峡部囊肿是子宫下段子宫肌层的低回声区，由先前剖宫产疤痕处子宫肌层中断引起。本研究旨在探讨剖宫产(CS)前母体细胞和炎症状态对峡部囊肿形成的影响。方法:这项前瞻性观察性研究在一家三级医院进行，纳入了既往有一次CS病史的妇女。产后6个月采集炎症及细胞参数，进行超声检查并分析。采用Logistic回归分析确定影响地峡膨出形成的潜在因素。结果:106例患者中，31例(29.2%)在既往CS后被诊断为峡部膨出。在人口统计学变量方面，两组之间没有显著差异。然而，峡部收缩组CS持续时间明显长于无峡部收缩组(42.58±8.77 vs 38.42±9.50 min, p = 0.03)。中性粒细胞/淋巴细胞比值(NLR)高于对照组，血小板/淋巴细胞比值(PLR)低于对照组(p < 0.001)。Logistic回归分析显示，NLR (OR[比值比]:0.23,95% CI[置信区间]:0.117 ~ 0.473,p < 0.001)和PLR (OR: 1.05, 95% CI: 1.027 ~ 1.078, p < 0.001)被确定为计划CS后峡部形成的独立预测因子。结论:炎性标志物，如NLR和PLR，可能有助于有一次CS病史的女性峡部囊肿的形成，揭示了潜在的病理生理学。
{"title":"Exploring the role of inflammatory parameters in predicting isthmocele formation following planned cesarean section: a study in patients with a history of one previous cesarean","authors":"Anıl Erturk, Gulay Gokce, Nergis Kender Erturk","doi":"10.18621/eurj.1315705","DOIUrl":"https://doi.org/10.18621/eurj.1315705","url":null,"abstract":"Objectives: Isthmocele is a hypoechoic area within the lower uterine segment myometrium, resulting from a discontinuation of the myometrium at the site of a previous cesarean scar. The aim of this study was to examine the influence of maternal cellular and inflammatory status prior to Cesarean Section (CS) on isthmocele formation. \u0000Methods: This prospective observational study was conducted in a tertiary hospital and included women with a history of one previous CS. The inflammatory and cellular parameters were collected and ultrasonographic examinations were conducted in the 6th postpartum month and then analyzed. Logistic regression analysis was performed to identify potential factors influencing isthmocele formation.\u0000Results: Of the 106 patients, 31 (29.2%) were diagnosed with isthmocele after one previous CS. There were no significant differences in terms of demographical variables between the groups. However, the duration of CS was significantly longer in the isthmocele group compared to the group without isthmocele (42.58 ± 8.77 vs. 38.42 ± 9.50 minutes, p = 0.03). The neutrophil-to-lymphocyte ratio (NLR) was higher and platelet-to-lymphocyte ratio (PLR) was lower in the isthmocele group (p < 0.001). Logistic regression analysis revealed that, NLR (OR [odds ratio]: 0.23, 95% CI [confidence interval]: 0.117- 0.473, p < 0.001) and PLR (OR: 1.05, 95% CI: 1.027-1.078, p < 0.001) were identified as independent predictors for isthmocele formation after planned CS. \u0000Conclusion: Inflammatory markers, such as NLR and PLR, may contribute to the formation of isthmocele in women with a history of one previous CS, shedding light on the underlying pathophysiology.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82794621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The aortic stiffness index beta (ASI-β), calculated noninvasively with the pressure change caused by arterial strain and volume changes on echocardiography, shows a strong correlation with invasive measurements of arterial stiffness. This study aimed to compare arterial stiffness and distensibility between peritoneal dialysis (PD) and hemodialysis (HD) and patients in renal replacement therapy. Methods: This cross-sectional and observational study analyzed 108 patients under renal replacement therapy (PD and HD). The aortic stiffness index beta (ASI-β) was calculated for each group. Results: The mean age of the patients in the study was 58.2±11.1 years, and 49 (45.4%) of the patients were female and 59 (54.6%) were male. Age, gender, comorbid rates, and levels of blood pressure and heart rate did not differ between the PD and HD groups. Blood pressure levels and heart rate. Mean aortic strain (5.6±1.9 vs. 9.4±2.8, p < 0.001) and median distensibility (1.5 vs. 2.9 cm, p < 0.001) were lower in the PD group than the HD group, while median ASI-β (11.6 vs. 6.2, p < 0.001) and mean E/e’ (10.6±2.9 vs. 9.2±2.3, p = 0.006) were higher in the PD group. The rate of concentric hypertrophy was higher in the PD group (47.5% vs. 23.5%, p = 0.005). Conclusion: PD patients have higher arterial stiffness and lower distensibility levels compared to HD patients. Therefore, patients with PD may be more prone to diastolic dysfunction, cardiovascular disease, and events.
目的:主动脉硬度指数β (ASI-β)是通过超声心动图上动脉应变和容积变化引起的压力变化无创计算得出的，它与动脉硬度的有创测量结果有很强的相关性。本研究旨在比较腹膜透析(PD)和血液透析(HD)患者与肾脏替代治疗患者的动脉僵硬性和扩张性。方法:本横断面观察性研究分析了108例接受肾脏替代治疗(PD和HD)的患者。计算各组主动脉硬度指数β (ASI-β)。结果:本组患者平均年龄为58.2±11.1岁，女性49例(45.4%)，男性59例(54.6%)。年龄、性别、合并症发生率、血压和心率水平在PD组和HD组之间没有差异。血压水平和心率。PD组平均主动脉应变(5.6±1.9比9.4±2.8,p < 0.001)和中位扩张率(1.5比2.9 cm, p < 0.001)低于HD组，而PD组中位ASI-β(11.6比6.2,p < 0.001)和平均E/ E′(10.6±2.9比9.2±2.3,p = 0.006)高于HD组。PD组同心圆肥大率较高(47.5% vs. 23.5%， p = 0.005)。结论:与HD患者相比，PD患者有较高的动脉僵硬度和较低的动脉扩张性。因此，PD患者可能更容易发生舒张功能障碍、心血管疾病和事件。
{"title":"Evaluation of arterial stiffness between peritoneal dialysis and hemodialysis in patients with renal replacement therapy","authors":"Tufan Günay, D. Topal, S. Akgür","doi":"10.18621/eurj.1296458","DOIUrl":"https://doi.org/10.18621/eurj.1296458","url":null,"abstract":"Objectives: The aortic stiffness index beta (ASI-β), calculated noninvasively with the pressure change caused by arterial strain and volume changes on echocardiography, shows a strong correlation with invasive measurements of arterial stiffness. This study aimed to compare arterial stiffness and distensibility between peritoneal dialysis (PD) and hemodialysis (HD) and patients in renal replacement therapy.\u0000Methods: This cross-sectional and observational study analyzed 108 patients under renal replacement therapy (PD and HD). The aortic stiffness index beta (ASI-β) was calculated for each group. \u0000Results: The mean age of the patients in the study was 58.2±11.1 years, and 49 (45.4%) of the patients were female and 59 (54.6%) were male. Age, gender, comorbid rates, and levels of blood pressure and heart rate did not differ between the PD and HD groups. Blood pressure levels and heart rate. Mean aortic strain (5.6±1.9 vs. 9.4±2.8, p < 0.001) and median distensibility (1.5 vs. 2.9 cm, p < 0.001) were lower in the PD group than the HD group, while median ASI-β (11.6 vs. 6.2, p < 0.001) and mean E/e’ (10.6±2.9 vs. 9.2±2.3, p = 0.006) were higher in the PD group. The rate of concentric hypertrophy was higher in the PD group (47.5% vs. 23.5%, p = 0.005).\u0000Conclusion: PD patients have higher arterial stiffness and lower distensibility levels compared to HD patients. Therefore, patients with PD may be more prone to diastolic dysfunction, cardiovascular disease, and events.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86493850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: We aimed to compare the accuracy of the depth of myometrial invasion determined by intraoperative frozen section in the early clinical stage of endometrioid type endometrial cancer, with the result of the final postoperative paraffin section. Methods: The study was carried out with 102 patients who were diagnosed with type 1-2 endometrioid endometrial cancer in the gynecology clinic of the state hospital between January 2015 and 2019. Retrospective demographic data, clinical characteristics, and pathology results of the patients who underwent surgical staging were recorded. Results: The mean age of the patients was 59.3 ± 9.1 years and 82.3% of the patients were in the postmenopausal period. The mean age of patients with a depth of myometrial invasion<1/2 was lower than myometrial invasion>1/2, which was statistically significant (p < 0.001). According to the final postoperative pathology results, 93.1% (n = 95) of the cases were diagnosed as FIGO stage 1. The subgroups were 66.7% stage 1a and 26.4% stage 1b. When the stage and grade distribution was made according to the final postoperative pathology result, stage 1a grade 2 endometrial cancer was the most common with a rate of 43.1%. Concordance of the intraoperative and postoperative pathology results for the depth of myometrial invasion was 84.3%, the specificity was 100%, the positive predictive value was 100%, and the negative predictive value was 86.76%. Conclusions: The accuracy of the intraoperative frozen section in endometrial cancers is quite higher. For this reason, intraoperative pathological examination results are important in terms of minimizing the complications of unnecessary surgery.
{"title":"Comparison of frozen section accuracy with final pathology results in early clinical stage of endometrioid type endometrial cancer","authors":"Levent Özgen, Gülten Özgen","doi":"10.18621/eurj.1307265","DOIUrl":"https://doi.org/10.18621/eurj.1307265","url":null,"abstract":"Objectives: We aimed to compare the accuracy of the depth of myometrial invasion determined by intraoperative frozen section in the early clinical stage of endometrioid type endometrial cancer, with the result of the final postoperative paraffin section. \u0000Methods: The study was carried out with 102 patients who were diagnosed with type 1-2 endometrioid endometrial cancer in the gynecology clinic of the state hospital between January 2015 and 2019. Retrospective demographic data, clinical characteristics, and pathology results of the patients who underwent surgical staging were recorded.\u0000Results: The mean age of the patients was 59.3 ± 9.1 years and 82.3% of the patients were in the postmenopausal period. The mean age of patients with a depth of myometrial invasion<1/2 was lower than myometrial invasion>1/2, which was statistically significant (p < 0.001). According to the final postoperative pathology results, 93.1% (n = 95) of the cases were diagnosed as FIGO stage 1. The subgroups were 66.7% stage 1a and 26.4% stage 1b. When the stage and grade distribution was made according to the final postoperative pathology result, stage 1a grade 2 endometrial cancer was the most common with a rate of 43.1%. Concordance of the intraoperative and postoperative pathology results for the depth of myometrial invasion was 84.3%, the specificity was 100%, the positive predictive value was 100%, and the negative predictive value was 86.76%.\u0000Conclusions: The accuracy of the intraoperative frozen section in endometrial cancers is quite higher. For this reason, intraoperative pathological examination results are important in terms of minimizing the complications of unnecessary surgery.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89780914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The National Comprehensive Cancer Network guidelines state that any nasal region with squamous or basal cell skin cancer is at high risk. Although Mohs surgery is the gold-standard procedure for many types of skin cancer, it is not applicable worldwide. A mean of 1.7 Mohs surgery stage is performed in cases of tumors. Nasal obstruction is a problem with Mohs surgery. In this study, we aimed to investigate nasal alar region nonmelanoma malignant skin tumor excision using immediate reconstruction without Mohs surgery. Methods: Ten patients underwent reconstruction surgery between 2018 and 2022. The inclusion criterion were ulcerated lesions in the nasal alar region measuring less than 1 cm in diameter, the lesions which were suspected either as basal cell carcinoma (BCC) or squamous cell carcinoma (SCC) on dermatoscopic examination, the patients who had intact nasal mucosa during anterior rhinoscopy. Results: The mean follow-up duration was 26 months. No patient required re-operation because of an excisional biopsy result that involved border proximity. We observed no serious complications or long-term recurrences. Conclusion: We recommend our algorithm for patients for whom Mohs surgery is not applicable.
{"title":"Immediate reconstruction of nasal alar defects after malignant skin tumor excision without mohs surgery","authors":"Mehmet Tapan, Ö. Özkan","doi":"10.18621/eurj.1335333","DOIUrl":"https://doi.org/10.18621/eurj.1335333","url":null,"abstract":"Objectives: The National Comprehensive Cancer Network guidelines state that any nasal region with squamous or basal cell skin cancer is at high risk. Although Mohs surgery is the gold-standard procedure for many types of skin cancer, it is not applicable worldwide. A mean of 1.7 Mohs surgery stage is performed in cases of tumors. Nasal obstruction is a problem with Mohs surgery. In this study, we aimed to investigate nasal alar region nonmelanoma malignant skin tumor excision using immediate reconstruction without Mohs surgery. \u0000Methods: Ten patients underwent reconstruction surgery between 2018 and 2022. The inclusion criterion were ulcerated lesions in the nasal alar region measuring less than 1 cm in diameter, the lesions which were suspected either as basal cell carcinoma (BCC) or squamous cell carcinoma (SCC) on dermatoscopic examination, the patients who had intact nasal mucosa during anterior rhinoscopy.\u0000Results: The mean follow-up duration was 26 months. No patient required re-operation because of an excisional biopsy result that involved border proximity. We observed no serious complications or long-term recurrences. \u0000Conclusion: We recommend our algorithm for patients for whom Mohs surgery is not applicable.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83774862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cervicogenic headache, characterized by referred pain perceived in the head but originating from the cervical spine, is a prevalent non-migraine headache impacting a significant proportion of the global population, particularly office workers. Recent studies have identified a co-occurrence of cervicogenic headaches with neck pain, often exacerbated by long hours of stationary sitting and computer use common in desk jobs. Despite the growing evidence supporting the effectiveness of chiropractic treatment in mitigating head and neck pain, a distinct gap persists in the literature concerning chiropractic interventions specifically targeting office workers suffering from cervicogenic headaches. This review aims to scrutinize the current literature on the effectiveness of chiropractic interventions on pain management and life quality improvement for office workers afflicted with cervicogenic headaches. Specifically, the review will delve into high-velocity, low-amplitude (HVLA) thrust maneuvers, a widely employed strategy in spinal manipulative therapy, an extension of chiropractic treatment. In the context of cervicogenic headaches, the link between the Rectus Capitis Posterior Minor (RCPM) muscle and the Dura Mater, and how neck strains affecting this connection can instigate headaches, will be explored. Through the comprehensive evaluation of existing literature and studies, this review seeks not only to elucidate the potential of chiropractic treatment in improving the life quality of office workers suffering from cervicogenic headaches, but also to stimulate further research in this essential yet under-explored area of study.
{"title":"Assessment of chiropractic intervention influence on pain and life quality in cervicogenic headache afflicted office workers: a review","authors":"Seyfettin Emrecan Ilter, Alper Gökçe","doi":"10.18621/eurj.1324556","DOIUrl":"https://doi.org/10.18621/eurj.1324556","url":null,"abstract":"Cervicogenic headache, characterized by referred pain perceived in the head but originating from the cervical spine, is a prevalent non-migraine headache impacting a significant proportion of the global population, particularly office workers. Recent studies have identified a co-occurrence of cervicogenic headaches with neck pain, often exacerbated by long hours of stationary sitting and computer use common in desk jobs. Despite the growing evidence supporting the effectiveness of chiropractic treatment in mitigating head and neck pain, a distinct gap persists in the literature concerning chiropractic interventions specifically targeting office workers suffering from cervicogenic headaches. This review aims to scrutinize the current literature on the effectiveness of chiropractic interventions on pain management and life quality improvement for office workers afflicted with cervicogenic headaches. Specifically, the review will delve into high-velocity, low-amplitude (HVLA) thrust maneuvers, a widely employed strategy in spinal manipulative therapy, an extension of chiropractic treatment. In the context of cervicogenic headaches, the link between the Rectus Capitis Posterior Minor (RCPM) muscle and the Dura Mater, and how neck strains affecting this connection can instigate headaches, will be explored. Through the comprehensive evaluation of existing literature and studies, this review seeks not only to elucidate the potential of chiropractic treatment in improving the life quality of office workers suffering from cervicogenic headaches, but also to stimulate further research in this essential yet under-explored area of study.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75142551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wardah Ashfaq, Iqra Iftikhar, Maria Fayyaz, Mahnam Khizer, S. Fatima, M. Younis
Phosphaturic mesenchymal tumor is a rare clinical condition and often causes osteomalacia due to tumor. Its diagnosis is often significantly delayed due to its rare occurrence in addition to the generalized and vague symptoms of their presentation. A 19-year-old female with a history of left facial nerve palsy, generalized weakness and hoarseness of voice revealed a dense mass in her brain. In this case, we reported successful application of a Ga-68 labeled DOTATATE PET/CT scan to identify the primary site and distant metastases of phosphaturic mesenchymal tumors and show the diagnostic value of Ga-68 labeled DOTATATE PET/CT imaging for the rare tumors.
{"title":"Detection of recurrent phosphaturic mesenchymal tumors by using Ga-68 DOTATATE PET/CT","authors":"Wardah Ashfaq, Iqra Iftikhar, Maria Fayyaz, Mahnam Khizer, S. Fatima, M. Younis","doi":"10.18621/eurj.1273409","DOIUrl":"https://doi.org/10.18621/eurj.1273409","url":null,"abstract":"Phosphaturic mesenchymal tumor is a rare clinical condition and often causes osteomalacia due to tumor. Its diagnosis is often significantly delayed due to its rare occurrence in addition to the generalized and vague symptoms of their presentation. A 19-year-old female with a history of left facial nerve palsy, generalized weakness and hoarseness of voice revealed a dense mass in her brain. In this case, we reported successful application of a Ga-68 labeled DOTATATE PET/CT scan to identify the primary site and distant metastases of phosphaturic mesenchymal tumors and show the diagnostic value of Ga-68 labeled DOTATATE PET/CT imaging for the rare tumors.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81077648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Aliyeva, Ozlem YAGIZ AGAYAROV, Gökçe Aksoy Yıldırım, T. Muderris, A. Dalğıç
Objectives: This study aims to contribute to the literature by presenting an overview of a 10-year experience by retrospectively examining the cases with a parotid mass from a tertiary referral center Methods: Two hundred fourteen patients were diagnosed with a parotid mass in the Otorhinolaryngology Clinic of HSU Izmir Bozyaka Training and Research Hospital between January 2009 and January 2019. Sociodemographic characteristics, diagnostic methods, surgical operations and complications, pathology results, and long-term follow-up results were retrospectively analyzed over the patients' files. SPSS Version 21.0 computer for data analysis. Results: Of 214 parotidectomies, 140 (75%) were male, 74 (35%) were female, mean age was 55 ±14 years (15-85 years). The most common diagnoses were 87 (40.7%) pleomorphic adenomas and 48 (22.4%) Wharton tumors. The most prevalent malignant tumors were reported as 18 (8.1%) mucoepidermoid carcinoma. The main type of surgery was superficial parotidectomy, performed in 192 (90%) patients. Facial paralysis was observed in 11 (5.1%) patients as the main postoperative complication. Conclusions: Considering the histopathological diagnosis of parotid tumors, the stage and grade of the tumor, surgery is generally preferred for treatment. More males are affected than women, especially in the middle ages.
{"title":"Surgical, histopathological, and clinical outcomes of parotid gland neoplasms: a 10-year tertiary single-center experience","authors":"A. Aliyeva, Ozlem YAGIZ AGAYAROV, Gökçe Aksoy Yıldırım, T. Muderris, A. Dalğıç","doi":"10.18621/eurj.1286422","DOIUrl":"https://doi.org/10.18621/eurj.1286422","url":null,"abstract":"Objectives: This study aims to contribute to the literature by presenting an overview of a 10-year experience by retrospectively examining the cases with a parotid mass from a tertiary referral center \u0000Methods: Two hundred fourteen patients were diagnosed with a parotid mass in the Otorhinolaryngology Clinic of HSU Izmir Bozyaka Training and Research Hospital between January 2009 and January 2019. Sociodemographic characteristics, diagnostic methods, surgical operations and complications, pathology results, and long-term follow-up results were retrospectively analyzed over the patients' files. SPSS Version 21.0 computer for data analysis.\u0000Results: Of 214 parotidectomies, 140 (75%) were male, 74 (35%) were female, mean age was 55 ±14 years (15-85 years). The most common diagnoses were 87 (40.7%) pleomorphic adenomas and 48 (22.4%) Wharton tumors. The most prevalent malignant tumors were reported as 18 (8.1%) mucoepidermoid carcinoma. The main type of surgery was superficial parotidectomy, performed in 192 (90%) patients. Facial paralysis was observed in 11 (5.1%) patients as the main postoperative complication. \u0000Conclusions: Considering the histopathological diagnosis of parotid tumors, the stage and grade of the tumor, surgery is generally preferred for treatment. More males are affected than women, especially in the middle ages.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74456338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melin Gecer, N. Büyükpınarbaşılı, Seval Turna, M. Besiroglu, Zuhal Gucin
Objectives: Gastric carcinoma (GC) is the fourth most common cause of cancer-related tumor deaths worldwide. The prognostic significance of CD44, CD133 and human epidermal growth factor receptor 2 (HER2) expression in GC remains controversial. Therefore, we aimed to investigate the relationship of CD44, CD133 and HER2 expression with clinicopathological features in metastatic and non-metastatic GC patients. Methods: A total of 139 patients with GC (68 with metastasis, 71 without metastasis) diagnosed were retrospectively analyzed. CD44 and CD133 expression were determined by immunohistochemical method in all cases. In addition, HER2 overexpression of the tumor was evaluated in patients with metastatic GC. Results: The CD133 positivity rate was 90.6% (n = 126) when all cases were considered, and that for CD44 was 84.9% (n = 118). There was no difference in CD133 and CD44 positivity (intensity or density) rates and between the total scores of metastatic and non-metastatic patients with GC (p > 0.05). HER2 positivity in metastatic cases was detected in 49 (70.1%) patients by immunohistochemical method. No correlation was found between CD133 total score and age, tumor size or depth, and HER2 scores in metastatic or non-metastatic cases (p > 0.05). In the correlation analyzes performed with CD44 scores, only a borderline significant correlation was found between CD44 scores and tumor size (r:0.175; p = 0.047) in non-metastatic cases. Conclusions: We demonstrated associations between CD44/CD133 expression and histological grade in all patients, between CD44 and tumor size in non-metastatic patients, and between HER2 and intestinal type (Lauren) in metastatic patients. The results of this study need to be confirmed by multicenter studies including large case series.
{"title":"Comparison of human epidermal growth factor receptor 2 and cancer stem cell markers like CD44 and CD133 expressions with clinicopathological parameters in gastric cancer","authors":"Melin Gecer, N. Büyükpınarbaşılı, Seval Turna, M. Besiroglu, Zuhal Gucin","doi":"10.18621/eurj.1296567","DOIUrl":"https://doi.org/10.18621/eurj.1296567","url":null,"abstract":"Objectives: Gastric carcinoma (GC) is the fourth most common cause of cancer-related tumor deaths worldwide. The prognostic significance of CD44, CD133 and human epidermal growth factor receptor 2 (HER2) expression in GC remains controversial. Therefore, we aimed to investigate the relationship of CD44, CD133 and HER2 expression with clinicopathological features in metastatic and non-metastatic GC patients. \u0000Methods: A total of 139 patients with GC (68 with metastasis, 71 without metastasis) diagnosed were retrospectively analyzed. CD44 and CD133 expression were determined by immunohistochemical method in all cases. In addition, HER2 overexpression of the tumor was evaluated in patients with metastatic GC.\u0000Results: The CD133 positivity rate was 90.6% (n = 126) when all cases were considered, and that for CD44 was 84.9% (n = 118). There was no difference in CD133 and CD44 positivity (intensity or density) rates and between the total scores of metastatic and non-metastatic patients with GC (p > 0.05). HER2 positivity in metastatic cases was detected in 49 (70.1%) patients by immunohistochemical method. No correlation was found between CD133 total score and age, tumor size or depth, and HER2 scores in metastatic or non-metastatic cases (p > 0.05). In the correlation analyzes performed with CD44 scores, only a borderline significant correlation was found between CD44 scores and tumor size (r:0.175; p = 0.047) in non-metastatic cases. \u0000Conclusions: We demonstrated associations between CD44/CD133 expression and histological grade in all patients, between CD44 and tumor size in non-metastatic patients, and between HER2 and intestinal type (Lauren) in metastatic patients. The results of this study need to be confirmed by multicenter studies including large case series.","PeriodicalId":22571,"journal":{"name":"The European Research Journal","volume":"05 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85851330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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