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Gambaran Anti-Plasmodium sp. Pada Anggota Tentara Nasional Indonesia Angkatan Darat Di Kota Cimahi 印度尼西亚军队在西玛希市的一名士兵的反塑料sp图片
Pub Date : 2018-11-29 DOI: 10.30651/jmlt.v2i1.1834
P. Naully, Gina Khairinisa, D. Saputri
Malaria is a disease caused by Plasmodium sp. The presence of such parasites in body can be characterized by the presence of anti-Plasmodium sp. antibodies. Malaria cases are still prevalent in Indonesia and generally occur in people who travel to endemic areas. One of the jobs that obliges its members to serve to various regions, including endemic areas is the Indonesian Army (TNI AD). Many Army personnel residing in Cimahi City. The purpose of this study is to determine the overview of malaria in members of the Army in Cimahi City. This study used a sample of 30 TNI AD who are residing in Cimahi City and have been assigned to various regions in Indonesia. Venipucture is only performed on respondents who have signed informed consent and filled out the interview form. Malaria screening is performed using immunochromatography that can detect anti-P. vivax and anti-P. falciparum antibodies, with a high degree of sensitivity and specificity. Of the 30 people, there were 4 people (13.3%) who had been infected with malaria and 2 (6.7%) of whom had experienced mixed malaria. All respondents who tested positive for malaria claimed to have been assigned to malaria endemic areas such as Papua and Maluku for several years.
疟疾是一种由疟原虫引起的疾病,这种寄生虫在体内的存在可以通过抗疟原虫抗体的存在来表征。疟疾病例在印度尼西亚仍然流行,通常发生在前往流行地区的人身上。要求其成员在不同地区,包括流行病地区服务的工作之一是印度尼西亚军队(TNI AD)。许多军队人员居住在西马希市。本研究的目的是确定在Cimahi市军队成员的疟疾概况。这项研究使用了30名居住在Cimahi市的TNI AD样本,他们被分配到印度尼西亚的各个地区。只有签署了知情同意书并填写了访谈表格的受访者才会进行静脉穿刺。疟疾筛查使用免疫层析可以检测抗p。间日疟和抗p。恶性疟原虫抗体,具有高度的敏感性和特异性。在这30人中,有4人(13.3%)感染过疟疾,其中2人(6.7%)经历过混合性疟疾。所有疟疾检测呈阳性的答复者都声称已被分配到诸如巴布亚和马鲁古等疟疾流行地区工作数年。
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引用次数: 0
Perbedaan Zona Hambat Terhadap Jamur Malassezia Furfur Antara Pemberian Ekstrak Umbi Bawang Putih (Allium Sativum Linn) Dengan Ekstrak Kulit Umbi Bawang Putih (Allium Sativum Linn) 与大蒜根茎提取物(Allium Sativum Linn)和大蒜根茎提取物(Allium Sativum Linn)之间的区域差异
Pub Date : 2018-05-28 DOI: 10.30651/jmlt.v1i2.1501
D. Ariana
Tinea versicolor or pitiriasis versicolor is a skin disorder caused by Malassezia furfur infection which is a fungal infection on the skin of the chronic surface. Clinical features is in the form of fine spots that colored white to brown black, this infection is also called a skin fungus with blotches. Treatment of Tinea versicolor can use chemical or traditional medicine. Chemical treatments such as creams or ointments cause sticky taste, while one of the traditional medicine is the bulb and skin of the garlic bulb (Allium sativum Linn) containing allicin substances that are efficacious as an anti-fungal.               This research is an experimental research with the aim to know the difference of inhibition zone to Malessezia furfur fungus. There are 3 treatments with 9 repetitions. The extraction method used is the soxhlet method. Anti-fungal activity test was done by using rating method, Saboroud Dextrose Agar (SDA) media which has been inoculated with suspension of Malassezia furfur with concentration 1.5x108 CFU/ml (Mc Farland standard).               Result of data analysis obtained by ANOVA p = 0,000 < α = 0,05, that there is difference of inhibition zone from treatment of garlic bulb extract and skin of garlic bulb (Allium sativum Linn). It is indicated that there is effect of giving garlic bulb extract (Allium sativum Linn) and garlic bulb skin (Allium sativum Linn) to Malassezia furfur fungus. Further tests were performed to compare mean treatment i.e. HSD test. It was obtained sig (p) 0,016 > α 0,05 which means bulb extract and garlic bulb skin (Allium sativum Linn) have different effect. Keywords: Tinea versicolor, Malassezia furfur, garlic bulb.
花斑癣或花斑癣是由毛马拉色菌感染引起的一种皮肤病,毛马拉色菌是一种慢性皮肤表面的真菌感染。临床特征是白色到棕黑色的小斑点,这种感染也被称为皮肤真菌和斑点。治疗花斑癣可以使用化学药物或传统药物。化学疗法,如面霜或软膏会引起粘稠的味道,而传统药物之一是大蒜的球茎和皮肤(Allium sativum Linn)含有大蒜素物质,具有有效的抗真菌作用。本研究是一项旨在了解不同抑菌带对糠秕孢菌抑菌带差异的实验研究。共3次治疗,重复9次。所采用的提取方法为索氏法。采用分级法,用浓度为1.5 × 108 CFU/ml (Mc Farland标准)的马拉色菌悬浮液接种Saboroud Dextrose Agar (SDA)培养基进行抗真菌活性试验。对数据进行方差分析,p = 0000 < α = 0.05,表明大蒜浸膏和大蒜皮处理的抑菌区存在差异。结果表明,大蒜提取物和大蒜皮对马拉色菌有一定的抑制作用。进行进一步的测试来比较平均处理,即HSD测试。得到sig (p) 0,016 > α 0,05,说明大蒜鳞茎提取物与大蒜鳞茎皮具有不同的作用。关键词:花斑癣,马拉色菌,大蒜球茎
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引用次数: 1
Perbedaan Pertumbuhan Bakteri Shigella dysentriae Pada Berbagai Konsentrasi Perasan Kulit Apel Manalagi (Malus sylvestris Mill) Secara In Vitro 苹果表皮(Malus sylvestris Mill)在体外不同浓度的情况下,会出现叶绿素(Shigella dysentriae细菌的生长差异
Pub Date : 2018-05-28 DOI: 10.30651/jmlt.v1i2.1483
Dita Artanti
Apple manalagi is one type of apple that is consumed by many Indonesian people, because it tastes sweet, tasty, easy to get and the price is quite affordable. The Manalagi apple rind contains some phytochemical derivatives of polyphenols that have antibacterial effects. Shigella dysentriae is a bacillus bacteria that causes acute diarrhea (dysentery) in most people who lack hygiene. One alternative to prevent the disease is to use natural ingredients as an antibacterial. The aim of this research is to know the different growth of S. dysentriae bacteria in various concentrations of Manalagi apple rind (Malus sylvestris Mill.) In vitro. The type of this study was experimental consisting of 7 treatments with 4 repetitions. The sample consisted of 7 concentrations of manalagi apple rind (100%, 50%, 25%, 12.5%, 6.25%, 3.125%, and 0% (control) .The data analysis used ANOVA test with 5% 0.05). The results showed that the growth of S.dysentriae bacteria was only at 0% concentration; 3.125%; 6.25%; 12.5%; and 25%. While at concentrations of 50% and 100% there was no growth of S.dysentriae bacterial colonies. The conclusion of this study proves that Manalagi apple rind has antibacterial power against S.dysentriae bacteria.Keywords: Shigella dysentriae, Manalagi Apple Rind (Malus sylvestris Mill).
马纳拉吉苹果(Apple manalagi)是许多印尼人喜欢吃的一种苹果,因为它吃起来很甜,很好吃,很容易买到,价格也很实惠。Manalagi苹果皮含有一些多酚的植物化学衍生物,具有抗菌作用。志贺氏痢疾杆菌是一种能引起大多数缺乏卫生习惯的人急性腹泻(痢疾)的芽孢杆菌。预防这种疾病的另一种选择是使用天然成分作为抗菌药物。本研究的目的是了解不同浓度的苹果果皮对痢疾杆菌生长的影响。体外。本研究为实验性研究,共7个处理,4个重复。样品由7种浓度的苹果皮组成(100%、50%、25%、12.5%、6.25%、3.125%和0%(对照),数据分析采用方差分析(ANOVA), 0.05为5%。结果表明,在0%浓度下,痢疾杆菌仅能生长;3.125%;6.25%;12.5%;和25%。而在50%和100%的浓度下,痢疾杆菌菌落没有生长。本研究的结论证明了马纳拉吉苹果皮对痢疾杆菌具有抑菌作用。关键词:痢疾志贺氏菌;苹果果皮;
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引用次数: 0
Respon Inflamasi Pada Perokok Pasif Di Kecamatan Pahandut Kota Palangka Raya Ditinjau Dari Jumlah Leukosit Dan Jenis Leukosit
Pub Date : 2018-05-28 DOI: 10.30651/JMLT.V1I2.1495
Rinny Ardina
Proporsi perokok pasif di Indonesia mencapai 40,5 persen dan 78,4 persen perokok pasif banyak terpapar asap rokok di dalam rumah.Setiap hembusan asap rokok mengandung 1015 radikal bebas oksidatif dan nikotinpenyebab leukositosis di dalam darah sebagai bentuk respon inflamasi.Jenis leukosit penunjuk inflamasi akibat asap rokok diawali neutrofilia, neutropenia, limfositosis, limfopenia dan monositosis sebagai bentuk respon inflamasi. Analisis deskriptif dengan rancangan cross sectional digunakan untuk memberikan gambaran respon inflamasi ditinjau dari jumlah leukosit dan jenis leukosit pada perokok pasif yang tinggal di kecamatan Pahandut kota Palangka Raya. Sampel yang diperoleh sebanyak 30 orang diambil dengan teknik Purposive Sampling dimulai dengan observasi, pembagian lembar inform consent, wawancara, pengisian kuesioner, pengambilan sampel darah dan pemeriksaan laboratorium menggunakan hematology analyzer dan apusan darah tepi. Data yang diperoleh dimuat dalam bentuk tabel dan dianalisis dan dideskripsikan dalam bentuk persentase (%). Pada 5 orang (17%) terjadi leukositosis, 2 orang (6%) neutropenia, 1 orang (3%) neutrofilia, 1 orang (3%) limfopenia, dan 6 orang (20%) limfositosis. Leukositosis menunjukkan penanda adanya perubahan imun sistemik, dimana selanjutnya terjadi rekrutmen sel inflamasi diantaranya neutrofil dan limfosit. Radikal bebas dan nikotin memicu inflamasi ditandai dengan neutrofilia dengan limfopenia relatif pada awal inflamasi dan selanjutnya berkembang menjadi limfositosis dengan neutropenia relatif.Proportion of passive smokers in Indonesia reached 40,5% and 78,4% of them were exposure of cigarette smoke in the house. Each puff of cigarette smoke contains 1015 of oxidative free radicals and nicotine that causes leukocytosis in the blood where it found as an inflammatory response. Either free radicals or nicotine can also cause of neutrophilia, neutropenia, lymphocytosis, lymphopenia, and monocytosis. This study aimed to overview of the inflammatory response in terms of white blood cell count and differential counting of leukocytes in passive smokers (housewives) who live in the district of Pahandut, Palangka Raya. Descriptive analysis with cross sectional design was used in this study. Samples obtained by 30 people were taken with Purposive Sampling technique. Procedure of collecting data starts from observation, distribution of informed consent, interview, answered of questionnaire, blood sampling and laboratory examination using hematology analyzer for measured of white blood cell count and peripheral blood smear for measured of differential counting of leukocytes. The data obtained were analyzed and described in percentage (%). This study found 5 people (17%) of leukocytosis, 2 people (6%) of neutropenia, 1 person (3%) of neutrophilia, 1 person (3%) of lymphopenia, and 6 people (20%) of lymphocytosis. Leukocytosis occurs because of the mechanism of leukocytes recruitment into inflammatory tissues and the types of leuko
印度尼西亚的被动吸烟者比例为40.5%,78.4%的被动吸烟者暴露在室内吸烟。每一缕烟中都含有1015个游离过氧化氢和血友病根治,作为炎症反应。烟烟引起的嗜烟血症,由神经细胞病、神经细胞病、淋巴细胞病、淋巴细胞病和单细胞病引起的炎症反应。交叉设计的描述性分析被用来描述住在帕洛阿尔托市帕坎托克街(Pahandut city of paorio)的被动吸烟者中,白细胞计数和白细胞类型所作的热辐射反应。30个样本是用采样技术采集的,开始于观察、分发信息交换单、采访、提交问卷、用血液学分析仪提取血样和实验室检查。获得的数据以表格形式加载,并以百分比(%)的形式分析和描述。5人患上白血病(17%),2人(6%)神经细胞病,1人(3%)神经细胞病,1人(3%)淋巴细胞病,6人(20%)淋巴细胞病。白细胞增多表明系统的免疫变化正在发生,而这些细胞又在其中招募神经细胞和淋巴细胞。自由基和尼古丁引发炎症,其特征是在炎症开始时相对存在的神经血友病,然后发展成相对神经细胞疾病的淋巴细胞。印尼对二手烟的比例达到40.5%和78.4%,即家中暴露香烟。每吸一根香烟的烟就会接触到血液中发现一种传染病,即黄斑白血病的迹象和尼古丁。任何一种自由基都可能是神经性、中性粒细胞、淋巴细胞、淋巴细胞和单胞杆菌的原因。这项研究是对白血球细胞terms反应的研究,以及生活在pahansmokers地区的家庭主妇的不同反应。这一研究中使用了交叉设计的描述分析。30个人参与的讣告样本技术。《收集数据进程》,《交换意见》,采访,回答问题,血液抽样和实验室研究受控制的数据是在percentage(%)对其进行分析和解析。这项研究发现5人(17%)白血病,2人(6%)神经细胞病,1人(3%)神经细胞病,1人(3%)淋巴细胞病,6人(20%)淋巴细胞病。白细胞增多导致淋巴细胞增多,白细胞增多,白细胞增多。自由激进分子和nicotine在triggering inftion上扮演一个主要角色。暴露于烟烟相关淋巴瘤和血液中相关淋巴瘤的放射暴露,并将逐渐形成淋巴瘤与神经细胞相关相关的炎症编年史。
{"title":"Respon Inflamasi Pada Perokok Pasif Di Kecamatan Pahandut Kota Palangka Raya Ditinjau Dari Jumlah Leukosit Dan Jenis Leukosit","authors":"Rinny Ardina","doi":"10.30651/JMLT.V1I2.1495","DOIUrl":"https://doi.org/10.30651/JMLT.V1I2.1495","url":null,"abstract":"Proporsi perokok pasif di Indonesia mencapai 40,5 persen dan 78,4 persen perokok pasif banyak terpapar asap rokok di dalam rumah.Setiap hembusan asap rokok mengandung 1015 radikal bebas oksidatif dan nikotinpenyebab leukositosis di dalam darah sebagai bentuk respon inflamasi.Jenis leukosit penunjuk inflamasi akibat asap rokok diawali neutrofilia, neutropenia, limfositosis, limfopenia dan monositosis sebagai bentuk respon inflamasi. Analisis deskriptif dengan rancangan cross sectional digunakan untuk memberikan gambaran respon inflamasi ditinjau dari jumlah leukosit dan jenis leukosit pada perokok pasif yang tinggal di kecamatan Pahandut kota Palangka Raya. Sampel yang diperoleh sebanyak 30 orang diambil dengan teknik Purposive Sampling dimulai dengan observasi, pembagian lembar inform consent, wawancara, pengisian kuesioner, pengambilan sampel darah dan pemeriksaan laboratorium menggunakan hematology analyzer dan apusan darah tepi. Data yang diperoleh dimuat dalam bentuk tabel dan dianalisis dan dideskripsikan dalam bentuk persentase (%). Pada 5 orang (17%) terjadi leukositosis, 2 orang (6%) neutropenia, 1 orang (3%) neutrofilia, 1 orang (3%) limfopenia, dan 6 orang (20%) limfositosis. Leukositosis menunjukkan penanda adanya perubahan imun sistemik, dimana selanjutnya terjadi rekrutmen sel inflamasi diantaranya neutrofil dan limfosit. Radikal bebas dan nikotin memicu inflamasi ditandai dengan neutrofilia dengan limfopenia relatif pada awal inflamasi dan selanjutnya berkembang menjadi limfositosis dengan neutropenia relatif.Proportion of passive smokers in Indonesia reached 40,5% and 78,4% of them were exposure of cigarette smoke in the house. Each puff of cigarette smoke contains 1015 of oxidative free radicals and nicotine that causes leukocytosis in the blood where it found as an inflammatory response. Either free radicals or nicotine can also cause of neutrophilia, neutropenia, lymphocytosis, lymphopenia, and monocytosis. This study aimed to overview of the inflammatory response in terms of white blood cell count and differential counting of leukocytes in passive smokers (housewives) who live in the district of Pahandut, Palangka Raya. Descriptive analysis with cross sectional design was used in this study. Samples obtained by 30 people were taken with Purposive Sampling technique. Procedure of collecting data starts from observation, distribution of informed consent, interview, answered of questionnaire, blood sampling and laboratory examination using hematology analyzer for measured of white blood cell count and peripheral blood smear for measured of differential counting of leukocytes. The data obtained were analyzed and described in percentage (%). This study found 5 people (17%) of leukocytosis, 2 people (6%) of neutropenia, 1 person (3%) of neutrophilia, 1 person (3%) of lymphopenia, and 6 people (20%) of lymphocytosis. Leukocytosis occurs because of the mechanism of leukocytes recruitment into inflammatory tissues and the types of leuko","PeriodicalId":22695,"journal":{"name":"THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST","volume":"344 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77149241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Perbandingan Pemeriksaan Leukosit Urine Segar Dengan Setelah 2 Jam Di Suhu Kamar 一个新鲜尿素检测与室温2小时后进行比较
Pub Date : 2018-05-28 DOI: 10.30651/jmlt.v1i2.1484
Nur Vita Purwaningsih
ABSTRACTBackground: Urinalysis is a parameter often requested by clinicians. The urinalysis parameters consist of macroscopic, microscopic or sedimental examination and urine chemistry examination. Urine examination is very important, especially in making the diagnosis. Procrastination delay results in errors in diagnosis and administration of drugs that lead to adverse outcomes of patients, analysis should be performed no later than 4 hours after sampling. Urine has a stability at room temperature ie for 1 hour, if urine is silenced long then the bacteria will multiply, so it can decompose NH3 (ammonia) which is alkaline. Under alkaline conditions, the pH in the urine will increase. This may affect the sediment component in the urine to rapid lysis so that the amount will be reduced General purpose of this study to determine the difference results of examination of fresh urine leukocytes compared after 2 hours at room temperature. Method: descriptive observasional with number of sample counted 20 sample. Result: Based on the test result, the positive percentage value in fresh urine is 100% and the positive percentage value in urine after 2 hours is 70%. In the Wilcoxon statistical test obtained p-value <0.001 (> 0.05). Conclusion: Based on the research that has been done then it can be concluded that there are differences in the results of fresh urine leukosit better than urine after 2 hours at room temperature.Keywords: Leukocyte urine, Fresh urine, delay. 
摘要背景:尿液分析是临床医生经常要求的一个参数。尿液分析参数包括宏观、微观或沉积检查和尿液化学检查。尿液检查非常重要,尤其是在诊断时。拖延导致诊断和给药错误,导致患者不良后果,分析应在采样后不迟于4小时进行。尿液在室温下具有稳定性,即1小时,如果尿液沉默时间长,细菌就会繁殖,因此它可以分解碱性的NH3(氨)。在碱性条件下,尿液中的pH值会升高。这可能会影响尿液中的沉淀物成分迅速溶解,从而使其数量减少。本研究的一般目的是确定在室温下2小时后新鲜尿液白细胞检测结果的差异。方法:描述性观察,样本数为20个。结果:根据检测结果,新鲜尿液阳性百分率为100%,2小时后尿液阳性百分率为70%。在Wilcoxon统计检验中得到p值0.05)。结论:根据所做的研究,可以得出结论,新鲜尿液白化结果优于室温下2小时的尿液白化结果。关键词:白细胞尿,新鲜尿,延迟。
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引用次数: 1
Bioaktif Belimbing Wuluh (Averhoa bilimbi (Linn.)) Terhadap Kadar Formalin Dalam Tahu
Pub Date : 2018-05-28 DOI: 10.30651/JMLT.V1I2.1541
Rinza Rahmawati Samsudin
This study aims to determine the influence of the juice of belimbing wuluh to the content of formalin in tofu and know the concentration of belimbing wuluh feeling is most effective in reducing the content of formalin in tofu. This study used a complete randomized design. The sample of this study was 30 tofu containing  formalin which was divided into 6 groups. The weight of each sample is 15 grams.The data of the research were analyzed by using anova test with 95% confidence level, then Duncan test with 95% confidence level. From the result of this research can be concluded that there is influence to formalin content in tofu. The content of formaldehyde in the highest to the lowest yields was found in soaking the belimbing wuluh with the concentrations is the group without treatment (8269.40 mg / Kg), 0% (1434.20 mg / Kg), 100% (762.00mg / Kg), 25% (573.80 mg / Kg), 75% (442.20 mg / kg), and 50% (162.00 mg / kg). The highest decrease in formaldehyde content in tofu by 98.40% occurred in the group K3 with the most effective 50% concentration to decrease the formalin content in tofu. Keyword : belimbing wuluh, tofu, formalin
本研究的目的是确定白翎乌露汁对豆腐中福尔马林含量的影响,了解白翎乌露感觉的浓度对降低豆腐中福尔马林含量最有效。本研究采用完全随机设计。本研究以30个含福尔马林的豆腐为样本,分为6组。每个样品的重量是15克。本研究资料采用95%置信水平的方差分析,再采用95%置信水平的Duncan检验。从研究结果可以得出豆腐中甲醛含量的影响因素。甲醛含量最高至最低的处理组为未处理组(8269.40 mg / Kg)、0% (1434.20 mg / Kg)、100% (762.00mg / Kg)、25% (573.80 mg / Kg)、75% (442.20 mg / Kg)和50% (162.00 mg / Kg)。K3组对豆腐中甲醛含量的降低幅度最大,达到98.40%,50%的浓度对豆腐中的甲醛含量降低效果最好。关键词:豆腐乳,豆腐,福尔马林
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引用次数: 0
Hubungan Kadar TSH Terhadap Kadar FT4 Pada Pasien Tiroid Di Bangkalan
Pub Date : 2018-05-28 DOI: 10.30651/jmlt.v1i2.1487
Ellies Tunjung Sari Maulidiyanti
AbstractThyroid disorder disease ranks second most in the list of metabolic diseases after diabetes mellitus (DM). Thyroid disease or Thyroid abnormalities is a condition of abnormalities in a person due to the disorder of the thyroid gland. TSH is a primary factor that controls thyroid cell growth and synthesis also thyroid hormone secretion. TSH secretion is stimulated by low levels of T3 and T4 and by the hormone TRH (Thyroid Releasing Hormone) the hypothalamus is inhibited by elevated levels of T3 and T4. T3 and T4 are circulating in the plasma, most of which are bound with proteins, Thyroid Binding Globulin (TBG) and a small part in free form that are Free Triiodotironine (FT3) and Free Thyroxine (FT4). The free hormone (FT3 and FT4) is an actively metabolic fraction which is known to be quantitative. Currently the measurement of free hormone levels should be part of a complete examination of the status of the thyroid gland. The purpose analyzes the levels of TSH, FT4 and proves the relationship between the two in patients with thyroid disorders. This examination by using ELISA method is with EIA competitive principles and sandwiches. The samples are serum of patients with thyroid disorders at RSUD Bangkalan and Farmalab Laboratory from October to November 2017.The 30 samples obtaines an average result of TSH level of 1.9 mIU / L and an average FT4 level of 2.8 ng / dl. Next test Kolmogorov-Smirnov and Spearrman's test results obtained if the variable one value rose (high) then the other variable down (low). It can be concluded that there is an opposite relationship between TSH levels and FT4 levels, if TSH levels increase, the FT4 level decreases, and so it is also in contrast Keywords: TSH, FT4, thyroid disorders
摘要甲状腺疾病是继糖尿病(DM)之后的第二大代谢性疾病。甲状腺疾病或甲状腺异常是一种由于甲状腺紊乱而导致的人的异常状况。TSH是控制甲状腺细胞生长和合成以及甲状腺激素分泌的主要因素。TSH分泌受低水平的T3和T4和激素TRH(甲状腺释放激素)的刺激,下丘脑受高水平的T3和T4的抑制。T3、T4在血浆中循环,大部分与蛋白、甲状腺结合球蛋白(Thyroid Binding Globulin, TBG)结合,小部分游离形式为游离三碘铁氨酸(free Triiodotironine, FT3)和游离甲状腺素(free thyroine, FT4)。游离激素(FT3和FT4)是一个活跃的代谢部分,已知是定量的。目前游离激素水平的测量应该是甲状腺状态全面检查的一部分。目的分析甲状腺疾病患者TSH、FT4水平,证明两者之间的关系。采用酶联免疫吸附法(ELISA)进行检测,符合EIA竞争原则和三明治法。样本是2017年10月至11月在邦卡兰RSUD和Farmalab实验室甲状腺疾病患者的血清。30个样本的TSH水平平均值为1.9 mIU / L, FT4水平平均值为2.8 ng / dl。接下来测试Kolmogorov-Smirnov和Spearrman的测试结果,如果变量一个值上升(高),那么另一个变量下降(低)。由此可见,TSH水平与FT4水平之间存在相反的关系,TSH水平升高,FT4水平降低,因此也相反。关键词:TSH, FT4,甲状腺疾病
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引用次数: 0
Gambaran Histologi Ginjal Tikus Wistar Yang Terpapar MSG Setelah Perlakuan Diberikan Jus Tomat Dan Diberhentikan Perlakuan Saja 树莓老鼠的肾组织图在得到番茄汁后暴露在味蕾中,不再治疗
Pub Date : 2018-05-01 DOI: 10.30651/jmlt.v1i2.1499
Yeti Eka sispita Sari
MSG causes many side effects on the body, but MSG has long been used as a food flavor that can bring tastes (umami) and play a role in strengthening the taste. The chemical structure of MSG is no different from Glutamic Acid (glutamate), it is one of the 20 amino acids that make up proteins in the body. So the use of MSG needs to be discontinued to prevent kidney damage due to continued consumption of MSG, two research were conducted to determine the effect of discharging of MSG consumption by being given tomato juice (1) and discharged without treatment (2), the second study was seen from the histology picture of rats wistar mouse.Methods were experimental with post test only control group design. The research (1) used 15 wistar rats divided into three groups: group I without treatment (pellet AD II and drinking water), group II was given MSG for 14 days and group III was given tomato juice and MSG for 14 days. The study (2) used 27 rats divided by 9 groups. The sample is selected by simple random sampling method. The mice were then gradually turned off on the 29th, 43rd and 57th days. There was no significant difference in mean number of normal and damaged proximal tubules in all treatment groups. The renal histologic features in the treatment group I (MSG) and the treatment group II (MSG and tomato juice) showed normal glomeruli, tubular epithelial tubules, and lumen tubular narrowing whereas in mice discharged without treatment there was no apparent difference between the two MSG Giving groups damage to proximal tubules and renal corpusculum and regeneration after 14 days of discontinuation of MSG. Conclusions from these two experiments occurred damage to the renal tubules Keywords: MSG, Kidney, Wistar Rat
味精对身体有很多副作用,但长期以来,味精一直被用作能带来味道(鲜味)的食品香精,并起到强化味道的作用。味精的化学结构与谷氨酸(谷氨酸)没有什么不同,它是构成人体蛋白质的20种氨基酸之一。因此,需要停止使用味精,以防止因持续食用味精而损害肾脏,我们进行了两项研究,以确定通过给予番茄汁(1)和不处理排出味精(2)的效果,第二项研究从大鼠wistar小鼠的组织学图中可以看出。方法采用单纯后验对照组设计。研究(1)选用15只wistar大鼠,分为3组:ⅰ组不给药(ADⅱ颗粒剂+饮水),ⅱ组给味精14 d,ⅲ组给番茄汁加味精14 d。研究(2)选用27只大鼠,分为9组。样本采用简单随机抽样方法选取。然后在第29、43和57天逐渐关闭小鼠。各组正常近端小管和损伤近端小管的平均数目无统计学差异。治疗组I(味精)和治疗组II(味精和番茄汁)的肾脏组织学特征显示肾小球、小管上皮小管和管腔小管狭窄正常,而在未治疗的小鼠中,两组在停药14天后,近端小管和肾小体的损伤和再生无明显差异。结论:味精、肾、Wistar大鼠肾小管均有损伤
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引用次数: 1
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THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST
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