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Management of Hospitalized Adult Patients with Coronavirus 2019 (COVID-19): A Therapeutic Guideline 2019冠状病毒肺炎(COVID-19)住院成人患者的管理:治疗指南
Pub Date : 2021-03-01 DOI: 10.52547/shefa.9.2.111
P. Kolivand, Vahid Dehestani, H. Kazemi
with ventilation. V) Early diagnosis and initiation of treatment have a significant effect on the patient’s recovery. Conclusion: The proposed guideline obtained from the evaluation of clinical trials, sys tematic reviews, and meta-analyses can improve the outcomes of patients with COVID-19 disease.e
与通风。5)早期诊断和开始治疗对患者的康复有重要作用。结论:从临床试验评价、系统评价和荟萃分析中得出的建议指南可以改善COVID-19患者的预后
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引用次数: 0
Examining the Necessity of Attention for Consciousness in Iconic Memory Using ModifiedStroop Paradigm 用修正stroop范式考察符号记忆中意识注意的必要性
Pub Date : 2021-03-01 DOI: 10.52547/shefa.9.2.91
Mehdi Afzalinia, I. Bigdeli, Javad Salehi Fadardi
Introduction: One of main challenging issues in cognitive science is the role of attention in consciousness. It is generally believed that attention is essential for consciousness. However, some s tudies have shown in some conditions, such as iconic memory, consciousness happens without attention. In previous s tudies, using iconic memory dual tasks in which attention is locally diverted to peripheral task in order to examine consciousness in the central task has caused the problem of expectation and previous knowledge in perception of the s timuli. The purpose of the present study was to tes t attention necessity for consciousness in iconic memory using the modified Stroop paradigm. Materials and Methods: Thirty Participants subjects were selected and randomly assigned to the partial and whole report groups. Results: Participants had significantly more correct responses in the partial group compared to the whole report group both in congruent and incongruent conditions. This indicates that attentional bias to word processing in incongruent conditions did not affect the correct responses compared to congruent conditions. Conclusion: Attention is not necessary for consciousness in iconic memory.y
认知科学的主要挑战之一是注意在意识中的作用。人们普遍认为注意力对于意识是必不可少的。然而,一些研究表明,在某些情况下,比如标志性记忆,意识是在没有注意的情况下发生的。在以往的研究中,通过将注意力局部转移到外围任务的标志性记忆双重任务来检验中心任务中的意识,导致了对刺激感知的期望和先前知识的问题。本研究的目的是利用改进的Stroop范式来研究符号记忆中意识的注意必要性。材料与方法:选取30名受试者,随机分为部分报告组和完整报告组。结果:在一致和不一致条件下,部分报告组的被试答对率明显高于全部报告组。这表明,与一致条件相比,不一致条件下对文字处理的注意偏差并不影响正确的反应。结论:在图示记忆中,注意不是意识的必要条件
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引用次数: 1
The Role of Astrocytes in the Central Nervous System: Physiological and Pathophysiological Conditions 星形胶质细胞在中枢神经系统中的作用:生理和病理生理条件
Pub Date : 2021-03-01 DOI: 10.52547/shefa.9.2.119
Samira Ramazi, F. Arani, Atlasi Safaei, Zeinab Abbasi, Zahra Heidari, hanieh Ghasemian nafchi, H. Mohammadsadeghi, F. Karimzadeh
shown that these diseases are associated with severe inflammation and as trocytes are among the mos t important cells that cause inflammation. Reactive as trocytes play a role in the pathology of various neurological diseases, such as Alzheimer’s disease, Parkinson’s disease, lateral amyotrophic sclerosis, multiple sclerosis, and Huntington’s. Alterations in neurotransmitters, cellular connections, receptors, signaling pathways (especially in the field of inflammation), secretion of inflammatory factors, aqueous channels, secretion of growth factors, protein deposition, ionic homeos tasis, and finally, changes in the size and number of as trocytes have been considered as the mos t important pathogenic mechanisms in as trocytes. Conclusion: Regulation of reactive as trocytes could be an effective clinical s trategy for the treatment of neurological and psychological diseases.s
表明这些疾病与严重的炎症有关,而胶质细胞是引起炎症的最重要细胞之一。反应性胶质细胞在各种神经系统疾病的病理中发挥作用,如阿尔茨海默病、帕金森病、侧索肌萎缩性硬化症、多发性硬化症和亨廷顿舞蹈症。神经递质、细胞连接、受体、信号通路(尤其是炎症领域)的改变、炎症因子的分泌、水通道、生长因子的分泌、蛋白质沉积、离子同质转运,最后是肌胶质细胞大小和数量的变化,被认为是肌胶质细胞最重要的致病机制。结论:调节反应性胶质细胞可作为治疗神经和心理疾病的一种有效的临床策略
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引用次数: 2
Predicting mindfulness effect on irritability with Bayesian models, regression and neural network 用贝叶斯模型、回归和神经网络预测正念对易怒的影响
Pub Date : 2021-03-01 DOI: 10.52547/shefa.9.2.35
Elham PourAfrouz, Saeed Setayeshi, I. Bigdeli, M. Pedram
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引用次数: 0
COVID-19 and Alzheimer's Disease: A Review of Mechanisms and Pathophysiology COVID-19与阿尔茨海默病:机制和病理生理学综述
Pub Date : 2021-03-01 DOI: 10.52547/shefa.9.2.151
Ali Mohammadkhanizadeh, F. Karimzadeh
hypoxia, oxidative s tress, or increased production of peripheral proinflammatory cytokines. s
缺氧、氧化应激或外周促炎细胞因子的产生增加。年代
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引用次数: 0
Comparison of the Effectiveness of Pivotal Response Treatment and Applied Behavioral Analysis on the Symptoms Severity and Executive Functions in Autistic Children 关键反应治疗与应用行为分析对自闭症儿童症状严重程度及执行功能的疗效比较
Pub Date : 2021-03-01 DOI: 10.52547/shefa.9.2.22
Pegah Tababaienavainobari, Mehran Solymani, B. Shalchi
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引用次数: 0
The Effect of Six-Week HIIT Swimming Exercise and Resveratrol Supplementation on the Level of SIRT3 in Frontal Lobe of Aged Rats 6周HIIT游泳运动和补充白藜芦醇对老年大鼠额叶SIRT3水平的影响
Pub Date : 2021-03-01 DOI: 10.52547/shefa.9.2.48
Amin Mehrabi, A. Gaeini, R. Nouri, F. Daryanoosh
groups compared to the control group. In there was a subs tantial difference between the mean values of SIRT3 protein among the three groups. SIRT3 levels in the EX and groups were significantly greater compared to the R group. Conclusion: Increasing the amount of SIRT3 in the response of HIIT swimming training in older rats indicating the involvement of this protein in metabolic pathways, antioxidant defense, and neuroprotection. to metabolic tissues, this in the frontal lobe of the brain.n
与对照组相比。三组间SIRT3蛋白的平均值有显著差异。与R组相比,EX组和组的SIRT3水平显著升高。结论:老年大鼠HIIT游泳训练反应中SIRT3含量的增加表明该蛋白参与代谢途径、抗氧化防御和神经保护。对代谢组织,这是在大脑的额叶
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引用次数: 3
Comparison of the Effectiveness of Mental Training and Treatment Based on Acceptance and Commitment on Rumination and Anxiety in Subjects with Body Dysmorphic Disorder 基于接纳与承诺的心理训练与治疗对躯体畸形障碍患者反刍与焦虑的效果比较
Pub Date : 2020-12-01 DOI: 10.52547/shefa.9.1.120
fahimeh maheronnaghsh, F. Naderi, saeed bakhtiyarpor, S. Safarzadeh
treatment based on acceptance and commitment were effective on rumination and worry. Furthermore, the efficacy of treatment based on acceptance and commitment was significantly greater than mental training. However, in the follow-up phase, no difference was observed between the effectiveness of the two interventions on rumination and worry. Conclusion: Mental training and acceptance and commitment therapy can be used to reduce rumination and worry in body dysmorphic disorder.
基于接受和承诺的治疗对反刍和忧虑有效。此外,基于接受和承诺的治疗效果显著高于心理训练。然而,在随访阶段,没有观察到两种干预措施在反刍和担忧方面的有效性之间的差异。结论:心理训练和接受承诺疗法可以减少身体畸形障碍患者的反刍和焦虑。
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引用次数: 1
Incidence of Ischemic and Thrombotic Events Following Nontraumatic Intracerebral and Subarachnoid Hemorrhages 非创伤性脑内和蛛网膜下腔出血后缺血性和血栓事件的发生率
Pub Date : 2020-12-01 DOI: 10.52547/shefa.9.1.6
M. Maghbooli, Reza Ahmadi, Ghazaleh Bahrami
the factors (hypertension, mellitus, atrial fibrillation, initial neurological indices (Glasgow scale, ICH and Hess and bleeding size in were evaluated 1 week, 1 month, 3 months, and 6 months after intracerebral hemorrhage and subarachnoid hemorrhage for the incidence of deep vein thrombosis, pulmonary embolism, ischemic heart disease, and ischemic s troke. Results: 165 patients had intracerebral hemorrhage and 38 patients had subarachnoid hemorrhage. The cumulative incidence of thromboischemic events in an unselected intracerebral hemorrhage and subarachnoid hemorrhage population was 31%. The overall incidence rates of deep vein thrombosis, pulmonary embolism, ischemic heart disease, and ischemic s troke after 6 months of intracerebral hemorrhage and subarachnoid hemorrhage onset were 10.9%, 5%, 10%, and 7.4%, respectively. The mean time to the events was 145.5 ± 5.5 days. Conclusion: Age, smoking, hypertension, diabetes mellitus, and atrial fibrillation were the significant independent risk factors for thromboischemic events. Age, higher ICH score, Hunt & Hess grade, and hemorrhage size >30cc have shown significant correlations with the development of deep vein thrombosis.
在脑出血和蛛网膜下腔出血后1周、1个月、3个月、6个月,分别评价各因素(高血压、糖尿病、房颤)、初始神经学指标(格拉斯哥评分、脑出血、Hess评分)和出血大小对深静脉血栓形成、肺栓塞、缺血性心脏病、缺血性卒中发生率的影响。结果:脑出血165例,蛛网膜下腔出血38例。在未选择的脑出血和蛛网膜下腔出血人群中,血栓缺血性事件的累积发生率为31%。脑出血和蛛网膜下腔出血发生6个月后,深静脉血栓形成、肺栓塞、缺血性心脏病和缺血性中风的总发生率分别为10.9%、5%、10%和7.4%。这些事件发生的平均时间为145.5±5.5天。结论:年龄、吸烟、高血压、糖尿病、房颤是血栓缺血性事件的重要独立危险因素。年龄、较高的ICH评分、Hunt & Hess分级、出血大小>30cc与深静脉血栓的发生有显著相关性。
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引用次数: 0
Effects of Endurance Training and Adenosine on the Expression of the A2B Gene on the Ischemic-Reperfusion Model of the Male Rat Brain 耐力训练和腺苷对雄性大鼠脑缺血-再灌注模型A2B基因表达的影响
Pub Date : 2020-12-01 DOI: 10.52547/shefa.9.1.79
Mansur Rahimi, F. Nameni
Introduction: Stroke is one of the mos t prevalent causes of death worldwide. Strategies that increase the resistance of neural cells to ischemia-induced damages are crucial to prevent brain damage. This study aimed to investigate the effect of endurance training and adenosine injection on the expression of the A2B gene after ischemia-reperfusion in Wistar rats. Materials and Methods: 40 male Wistar rats (220±20g) were divided into four groups; endurance training +adenosine+ ischemia, ischemia+ adenosine, endurance training+ ischemia, and control. Ischemic induction was conducted through the common carotid artery ligation. After the ischemic insult, an endurance training protocol was performed. Eight weeks after ischemic induction and exercise protocol, blood samples were taken from rats, and expression of the A2B gene was measured. Results: There was a significant difference in the expression of the A2B gene between the ischemic control and endurance training +adenosine+ ischemia groups. Conclusion: It seems endurance training protocol protected neurons from ischemic injury and improved rat brain function. The administration of adenosine has also played an important role in the regulatory mechanisms of ischemic-reperfusi
中风是世界上最普遍的死亡原因之一。增强神经细胞对缺血损伤的抵抗力是预防脑损伤的关键。本研究旨在探讨耐力训练和腺苷注射对Wistar大鼠缺血再灌注后A2B基因表达的影响。材料与方法:雄性Wistar大鼠40只(220±20g),随机分为4组;耐力训练+腺苷+缺血,缺血+腺苷,耐力训练+缺血,和控制。通过结扎颈总动脉进行缺血诱导。缺血损伤后,进行耐力训练。缺血诱导和运动方案后8周,取大鼠血样,测定A2B基因的表达。结果:缺血对照组与耐力训练+腺苷+缺血组A2B基因表达差异有统计学意义。结论:耐力训练方案似乎可以保护神经元免受缺血性损伤,改善大鼠脑功能。腺苷的给药也在缺血再灌注的调控机制中发挥了重要作用
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引用次数: 1
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The Neuroscience Journal of Shefaye Khatam
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