Pub Date : 2018-01-01DOI: 10.6116/kjh.2018.33.4.19
Kyeong Jo Kim, Hae-Jin Park, I. G. Kim, M. Kim, Mi-Rae Shin, S. Roh
{"title":"Evaluation on Immunopotentiation Activities of Combined Extract of Silkworm and Cinnamomum cassia in vivo","authors":"Kyeong Jo Kim, Hae-Jin Park, I. G. Kim, M. Kim, Mi-Rae Shin, S. Roh","doi":"10.6116/kjh.2018.33.4.19","DOIUrl":"https://doi.org/10.6116/kjh.2018.33.4.19","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"48 1","pages":"19-26"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87954187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.6116/KJH.2018.33.3.45
Wenbing Xu, Soonil Kim, H. Choi, Dong Hee Kim
Objectives : In cases of osteoarthritis, the hypofunction of the cartilage and joint leads to a limited range of joint motion, swelling, and pain, which is generally treated using pharmaceutical drugs (e.g., anti-inflammatory agents, cartilage protectants, and nonsteroidal anti-inflammatory drugs) or replacement arthroplasty. However, long-term drug treatment is associated with adverse effects on the gastrointestinal systems. The present study aimed to evaluate the ability of Giheolsotong-hwan to treat of osteoarthritis symptoms in the MIA-induced rat model based on histological analysis, and factors that are associated with inflammation and bone mineral metabolism. Methods : Giheolsotong-hwan was administered orally at doses of 200 mg/kg/day or 400 mg/kg/day for 2 weeks before direct injection of monosodium iodoacetate (3 mg/50μl of 0.9% saline) into the intra-articular space of the rats’ right knee. The rats subsequently received the same doses of oral Giheolsotong-hwan for another 4 weeks. We evaluated the treatment effects based on serum biomarkers and histopathological analysis of the knee joints. Results : Compared to those in control rats, the Giheolsotong-hwan treatments significantly decreased the serum concentration of inflammation factors (i.e., IL-1β, IL-6, TNF-α, PGE2, and LTB4), and bone degrade factors (i.e., MMP-9, CTX-II, and COMP). In addition, the Giheolsotong-hwan treatments significantly increased the concentration of glycosaminoglycans of bone defence factors, but no chage the TIMP-1. Furthermore, the Giheolsotong-hwan treatments effectively preserved the knee cartilage and proteoglycan. Conclusion : The results indicate that Giheolsotong-hwan treated osteoarthritis symptoms. Thus, Giheolsotonghwan may be a novel oriental therapeutic option for the management of osteoarthritis.
{"title":"Effects of gihyeolsotong-hwan on monosodium iodoacetate-induced osteoarthritis in rats","authors":"Wenbing Xu, Soonil Kim, H. Choi, Dong Hee Kim","doi":"10.6116/KJH.2018.33.3.45","DOIUrl":"https://doi.org/10.6116/KJH.2018.33.3.45","url":null,"abstract":"Objectives : In cases of osteoarthritis, the hypofunction of the cartilage and joint leads to a limited range of joint motion, swelling, and pain, which is generally treated using pharmaceutical drugs (e.g., anti-inflammatory agents, cartilage protectants, and nonsteroidal anti-inflammatory drugs) or replacement arthroplasty. However, long-term drug treatment is associated with adverse effects on the gastrointestinal systems. The present study aimed to evaluate the ability of Giheolsotong-hwan to treat of osteoarthritis symptoms in the MIA-induced rat model based on histological analysis, and factors that are associated with inflammation and bone mineral metabolism. Methods : Giheolsotong-hwan was administered orally at doses of 200 mg/kg/day or 400 mg/kg/day for 2 weeks before direct injection of monosodium iodoacetate (3 mg/50μl of 0.9% saline) into the intra-articular space of the rats’ right knee. The rats subsequently received the same doses of oral Giheolsotong-hwan for another 4 weeks. We evaluated the treatment effects based on serum biomarkers and histopathological analysis of the knee joints. Results : Compared to those in control rats, the Giheolsotong-hwan treatments significantly decreased the serum concentration of inflammation factors (i.e., IL-1β, IL-6, TNF-α, PGE2, and LTB4), and bone degrade factors (i.e., MMP-9, CTX-II, and COMP). In addition, the Giheolsotong-hwan treatments significantly increased the concentration of glycosaminoglycans of bone defence factors, but no chage the TIMP-1. Furthermore, the Giheolsotong-hwan treatments effectively preserved the knee cartilage and proteoglycan. Conclusion : The results indicate that Giheolsotong-hwan treated osteoarthritis symptoms. Thus, Giheolsotonghwan may be a novel oriental therapeutic option for the management of osteoarthritis.","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"28 1","pages":"45-53"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90566099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A literature study on dermatological efficacy and drug induced liver injury of Dictamnus dasycarpus Turcz","authors":"Youjung Lee, Seoyoung C. Kim, Hyungwoo Kim","doi":"10.6116/KJH.2018.33.1.9","DOIUrl":"https://doi.org/10.6116/KJH.2018.33.1.9","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"47 1","pages":"9-15"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80379914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.6116/KJH.2018.33.4.69
Min Ji Lee, Se-Eun Lee, N. Choi, S. Jo, Suin Cho
{"title":"Effects of hexane fraction of Dracocephalum palmatum Stephan leaf on human-derived prostate cancer cell death","authors":"Min Ji Lee, Se-Eun Lee, N. Choi, S. Jo, Suin Cho","doi":"10.6116/KJH.2018.33.4.69","DOIUrl":"https://doi.org/10.6116/KJH.2018.33.4.69","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"43 2","pages":"69-76"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91402031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.6116/KJH.2018.33.2.53
Jeong Mi Jin, So Young Kim, Y. Kim, Eun-Tag Lee, Sung-Tae Choo, Hankon Kim, Mi Ryeo Kim
{"title":"The effect of Plantaginis asiaticae Folium on lipid accumulation in 3T3-L1 adipocytes by extraction conditions","authors":"Jeong Mi Jin, So Young Kim, Y. Kim, Eun-Tag Lee, Sung-Tae Choo, Hankon Kim, Mi Ryeo Kim","doi":"10.6116/KJH.2018.33.2.53","DOIUrl":"https://doi.org/10.6116/KJH.2018.33.2.53","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"90 1","pages":"53-58"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84502885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-30DOI: 10.6116/kjh.2017.32.1.83
Myung-Gyou Kim, I. Seo, K. Leem, Tae-Joon Jeong, Jinseok Kim
{"title":"Effects of Achyranthis Japonicae Radix-containing mixture on monosodium iodoacetate-induced osteoarthritis in rats","authors":"Myung-Gyou Kim, I. Seo, K. Leem, Tae-Joon Jeong, Jinseok Kim","doi":"10.6116/kjh.2017.32.1.83","DOIUrl":"https://doi.org/10.6116/kjh.2017.32.1.83","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"49 1","pages":"83-89"},"PeriodicalIF":0.0,"publicationDate":"2017-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80729532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-30DOI: 10.6116/kjh.2017.32.1.15
J. Yoon, Y. Lee, H. Kim, Y. M. Ahn, Xian Jun Jin, M. Hong, Jin Seok Hwang, H. Lee, D. Kang
{"title":"Improvement Effect of Sibjotang on Blood Glucose and Renal Dysfunction in Type II Diabetic Mice","authors":"J. Yoon, Y. Lee, H. Kim, Y. M. Ahn, Xian Jun Jin, M. Hong, Jin Seok Hwang, H. Lee, D. Kang","doi":"10.6116/kjh.2017.32.1.15","DOIUrl":"https://doi.org/10.6116/kjh.2017.32.1.15","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"119 1","pages":"15-23"},"PeriodicalIF":0.0,"publicationDate":"2017-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86188153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-30DOI: 10.6116/kjh.2017.32.1.63
Jungbin Song, Donghun Lee, Young Sik Kim, Seunggyeong Lee, Jin-Sook Bae, Hocheol Kim
{"title":"A 14-day Repeated Dose Oral Toxicity Study of HT042 in Sprague-Dawley Rats","authors":"Jungbin Song, Donghun Lee, Young Sik Kim, Seunggyeong Lee, Jin-Sook Bae, Hocheol Kim","doi":"10.6116/kjh.2017.32.1.63","DOIUrl":"https://doi.org/10.6116/kjh.2017.32.1.63","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"13 1","pages":"63-68"},"PeriodicalIF":0.0,"publicationDate":"2017-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89533293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ji-Eun Lee, S. Roh, Han-Young Kim, Kun-Hoae Kim, Kim，Seung-Hyung
{"title":"Enhancement of Immune Activities of Canavalia gladiata & Arctium lappa complexes in immobilization stress mouse model.","authors":"Ji-Eun Lee, S. Roh, Han-Young Kim, Kun-Hoae Kim, Kim，Seung-Hyung","doi":"10.6116/kjh.2017.32.1.1","DOIUrl":"https://doi.org/10.6116/kjh.2017.32.1.1","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"146 1","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2017-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76746607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-30DOI: 10.6116/KJH.2017.32.1.41
In-rak Kim
{"title":"The Origin and Daily Dose of Allii Chinensis Bulbus in Treatise on Cold Damage Diseases and Synopsis of Prescriptions of the Golden Chamber","authors":"In-rak Kim","doi":"10.6116/KJH.2017.32.1.41","DOIUrl":"https://doi.org/10.6116/KJH.2017.32.1.41","url":null,"abstract":"","PeriodicalId":22911,"journal":{"name":"The Korea Journal of Herbology","volume":"19 1","pages":"41-45"},"PeriodicalIF":0.0,"publicationDate":"2017-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73483300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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