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Computational Simulation of Atherosclerosis Progression Associated with Blood Pressure in a 2-D Idealized Human Carotid Artery Model 二维理想人类颈动脉模型中与血压相关的动脉粥样硬化进展的计算模拟
Pub Date : 2022-07-21 DOI: 10.2174/18741231-v16-e2205260
E. Alagbe, T. E. Amoo, A. O. Ayeni, Oluwakayode S. Oyedele, Vershima D. Ashiekaa
Cardiovascular diseases are a known health threat with no respect for age. The need to understand the initiation and progress of the disease is expedient in proper diagnosis and management of the disease. The work is targeted at simulating the effect of elevated blood pressure on the initiation and development of plaque over time concerning wall shear stress, WSS and plaque wall stress, and PWS. Conditions such as blood velocity, pressure, and arterial wall conditions associated with blood flow in arteries, as well as patient-specific characterization related to these variables and conditions, were plugged into modified models in the COMSOL multiphysics software. The artery was modeled as an idealized 2-D carotid artery model. Results showed that the WSS distribution with respect to changes with a blood pressure of 500 Pa gave the highest WSS value at the plaque neck and 1500 Pa gave the highest WSS value in the regions close to the plaque root. It was also observed that as the plaque size increased, the region experiencing severely high values for WSS also expanded. It can be recommended that blood pressure monitoring is necessary to curb the attendant cardiovascular diseases associated with high blood pressure.
心血管疾病是一种众所周知的健康威胁,与年龄无关。了解该疾病的发生和发展过程有助于对该疾病进行正确的诊断和管理。这项工作的目的是模拟血压升高对斑块发生和发展的影响,随着时间的推移,涉及壁剪切应力、WSS和斑块壁应力以及PWS。与动脉血流相关的血流速度、血压和动脉壁状况等条件,以及与这些变量和条件相关的患者特异性特征,都被插入到COMSOL多物理场软件的修改模型中。将该动脉建模为理想的二维颈动脉模型。结果表明,随血压变化的WSS分布在斑块颈部最高,1500 Pa时靠近斑块根部的WSS值最高。还观察到,随着斑块大小的增加,经历严重高值WSS的区域也扩大。建议血压监测是必要的,以抑制伴随的心血管疾病与高血压相关。
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引用次数: 0
A Review on CO2 Absorption using Chemical Solvents at Low and High CO2 Partial Pressure Conditions in a Packed Column 填料塔中低、高CO2分压条件下化学溶剂吸收CO2的研究进展
Pub Date : 2022-06-21 DOI: 10.2174/18741231-v16-e2204140
H. Halim, V. Rajiman, A. Shariff
CO2 removal is important for industrial flue gas treatment, biogas enhancement, and natural gas (NG) processing applications. Chemical absorption using an amine-based solvent is a proven technology for CO2 removal from various gases. In recent years, various promising amine solvents have been investigated, either as single or blended solutions, to enhance the CO2 absorption process at low and high CO2 partial pressure conditions. Low CO2 partial pressures (1 – 47 kPa) have been utilized in numerous research works focusing on flue gas treatment and biogas enhancement applications. On the other hand, high CO2 partial pressures were instead applied in NG processing ranging between 750 and 1600 kPa. To provide more insight into the current trends, existing research on CO2 absorption in amine-based solvents is presented in this review focusing on absorption performance in a packed column at low and high CO2 partial pressures. Reports on the effect of different parameters, namely CO2 partial pressure, gas, and liquid flow rates, amine concentrations, and liquid temperature, on the removal of CO2 in the packed column are included. Based on the review, the future direction is further highlighted in this area.
CO2去除对于工业烟气处理、沼气强化和天然气处理应用具有重要意义。使用胺基溶剂的化学吸收是一种经过验证的从各种气体中去除二氧化碳的技术。近年来,人们研究了各种有前途的胺类溶剂,无论是作为单一溶液还是混合溶液,以增强低和高CO2分压条件下的CO2吸收过程。低二氧化碳分压(1 - 47千帕)已被用于许多侧重于烟气处理和沼气强化应用的研究工作。另一方面,高CO2分压被应用于NG加工,范围在750和1600千帕之间。为了更深入地了解当前的趋势,本文综述了胺基溶剂中CO2吸收的现有研究,重点介绍了填料柱在低和高CO2分压下的吸收性能。报告了不同的参数,即CO2分压、气体和液体流速、胺浓度和液体温度,对填料柱中CO2的去除的影响。在回顾的基础上,进一步强调了该领域的未来发展方向。
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引用次数: 0
Water Absorption Enhancement of Sodium Poly Acrylate and Poly(2-Acrylamido-2-Methylpropane Sulphonic Acid) Based Hydrogel Mixtures 聚丙烯酸钠和聚(2-丙烯酰胺-2-甲基丙烷磺酸)基水凝胶混合物的吸水性增强
Pub Date : 2021-12-24 DOI: 10.2174/1874123102115010049
Sohair A. Darwish, I. Ibrahim, N. Mostafa, M. Radwan, M. A. Sadek, Hany A. Elazab
Hydrogels are hydrophilic polymers which are cross-linked to form three-dimensional structures, which can absorb, swell and retain huge amountsof water or aqueous fluids. This paper reports the preparation and characterisation of Poly(2-Acrylamido-2-Methylpropane Sulphonic Acid) (PAMPS) hydrogel with differentcrosslinking intensities. 2-Acrylamido-2-methylpropane sulfonic acid (AMPS)monomer was purchased from Alfa Aesar Company as reagentgrade. It was used as received (>98% purity) without anyfurther purification. PAMPS hydrogel was prepared by free radical crosslinkingsolution polymerization of AMPS in water at roomtemperature under a nitrogen blanket in cylindrical glass tubes.The characteristics of the obtained PAMPS hydrogel were compared with those of commercial sodium polyacrylateshydrogel. It was found that decreasing the crosslinker weight improved the absorbance capacity but to a limit. The suggested reasons werediscussed. The mixture showed higher absorbance rate than PAMPS, and bigger absorbance capacity than sodium polyacrylates. This paper investigates the effect of crosslinker ratio on theswelling capacity of PAMPS. It was found that as thecrosslinking ratio decreases, the porosity of the hydrogelincreases, thus improving the swelling capacity.
水凝胶是交联形成三维结构的亲水聚合物,可以吸收、膨胀并保留大量的水或含水流体。本文报道了不同交联强度的聚2-丙烯酰胺-2-甲基丙烷磺酸(PAMPS)水凝胶的制备和表征。2-丙烯酰胺-2-甲基丙烷磺酸(AMPS)单体作为试剂级购自Alfa Aesar公司。直接使用(纯度>98%),无需进一步提纯。在圆柱形玻璃管中,氮气包层下,采用自由基交联溶液聚合法制备了PAMPS水凝胶。将所制得的PAMPS水凝胶与市售的聚丙烯酸钠水凝胶进行了性能比较。研究发现,降低交联剂的质量对吸光度有一定的改善,但效果有限。讨论了提出的理由。其吸光度比PAMPS高,吸光度比聚丙烯酸钠大。研究了交联剂配比对PAMPS溶胀性能的影响。研究发现,随着交联率的降低,水凝胶的孔隙度增加,从而提高了水凝胶的溶胀能力。
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引用次数: 1
Neutralizing Aminesin Boiler Steam and Humidified Indoor Air 中和锅炉蒸汽和加湿室内空气中的胺
Pub Date : 2021-12-24 DOI: 10.2174/1874123102115010041
A. Gomes, Ye Tao, A. Bhuiyan, Dongjie Guan, F. Memarzadeh
The health and comfort of the indoor population have been impacted by the humidity. While people are increasingly spending more time indoors, the presence of pollutants and lack of proper humidification in indoor air have significant risk factors that may lead to multiple health problems. By applying the right air purification and/or humidification system, the adverse effects of poor indoor air quality can be minimized. Direct steam addition is a common technique to humidify the indoor air of a building. Carbon dioxide or other acidic process contaminants may dissolve in steam or steam condensate that will consequently decrease the pH and make it corrosive for the steam distribution system. To avoid that, neutralizing amines are added to steam that keeps the pH neutral or slightly alkaline(pH 7.5-9.0). However, neutralizing amines have some toxic effects. OSHA, FDA, and NIOSH prescribe maximum concentration limits for them in indoor air. The Central Utility Plant (CUP) of National Institutes of Health (NIH) uses a 50:50 blend of cyclohexylamine and diethylaminoethanol as neutralizing agents for the steam. The CUP at NIH presents the results of monitoring the concentration level of amines through mass balance, online monitoring at specified location of the steam distribution system and field measurement in humidified indoor air at buildings on campus. Through theoretical calculation backed up by field measurement, the amine concentration of indoor air is determined to be well below the FDA regulated limits.
室内人群的健康和舒适受到湿度的影响。虽然人们在室内的时间越来越长,但污染物的存在和室内空气缺乏适当的加湿是可能导致多种健康问题的重大风险因素。通过应用正确的空气净化和/或加湿系统,可以最大限度地减少室内空气质量差的不利影响。直接加蒸汽是一种常用的加湿建筑物室内空气的技术。二氧化碳或其他酸性过程污染物可能会溶解在蒸汽或蒸汽冷凝水中,从而降低pH值并使其对蒸汽分配系统具有腐蚀性。为了避免这种情况,在蒸汽中加入中和胺,使pH值保持中性或微碱性(pH值7.5-9.0)。然而,中和胺有一些毒性作用。OSHA, FDA和NIOSH规定了它们在室内空气中的最大浓度限制。美国国立卫生研究院(NIH)的中央公用事业工厂(CUP)使用50:50的环己胺和二乙胺乙醇混合物作为蒸汽的中和剂。美国国立卫生研究院的CUP通过质量平衡、蒸汽分配系统指定位置的在线监测和校园建筑物加湿室内空气的现场测量来监测胺的浓度水平。通过现场测量支持的理论计算,确定室内空气中的胺浓度远低于FDA规定的限制。
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引用次数: 0
Fast and Facile Voltammetric Detection of Acetaminophen at Poly (DL-phenylalanine) Modified Dysprosium-Copper Oxide Nanoparticle/Carbon Composite Paste Electrode 聚(dl -苯丙氨酸)修饰的氧化镝纳米颗粒/碳复合浆料电极上对乙酰氨基酚的快速简便伏安检测
Pub Date : 2021-11-17 DOI: 10.2174/1874123102115010031
Shankar A. Itagi, J. G. Manjunatha, M. M. Charithra, P. Mallu, S. Sandeep, C. S. Karthik, Girish Tigari, Donnankatte N. Varun
The voltammetric sensing of Acetaminophen (AN) using modified Dysprosium Copper Oxide (DyCuO) Nanoparticles (NP) mixed Carbon Paste Electrode (MCPE) was successfully developed. The modification of bare NPMCPE was achieved by the polymerisation of DL-Phenylalanine (DLPA). The electroanalysis of the AN was achieved by utilizing the Cyclic voltammetry (CV) approaches. The crystallographic nature of the nanoparticle was studied via X-ray Powder Diffraction (XRD) technique. The surface morphology and electrochemical feature of the prepared electrode were evaluated by Field Emission Scanning Electron Microscopy (FE-SEM) and Electrochemical Impedance Spectroscopy (EIS) techniques. The modified sensor exhibited an excellent electrocatalytic activity towards the electroanalysis of the AN. Several aspects, such as the number of polymerisation cycles, variation of pH, and the impact of scan rate were investigated in 0.2 M supporting electrolyte (pH 7) at a sweep rate of 0.1 Vs-1. The suggested sensor shows a very low detection limit (11.95×10-8 M) with a linear range of 2.0 to 50.0 µM, which exhibits excellent sensitivity. The stable and reusable sensor was applied for the estimation of AN in the tablet sample. Thus, P(DLPA)MNPMCPE was utilized as the most capable sensor for the voltammetric detection of AN.
成功地利用修饰的氧化铜镝纳米颗粒(NP)混合碳糊电极(MCPE)实现了对乙酰氨基酚(AN)的伏安感应。通过dl -苯丙氨酸(DLPA)的聚合实现了裸NPMCPE的改性。AN的电分析是利用循环伏安法(CV)方法实现的。利用x射线粉末衍射(XRD)技术研究了纳米颗粒的晶体性质。采用场发射扫描电镜(FE-SEM)和电化学阻抗谱(EIS)技术对制备电极的表面形貌和电化学特性进行了表征。改进后的传感器对an的电分析表现出优异的电催化活性。在0.2 M的负载电解质(pH为7)中,以0.1 Vs-1的扫描速率研究了聚合循环次数、pH变化和扫描速率的影响。该传感器具有极低的检测限(11.95×10-8 M),线性范围为2.0 ~ 50.0µM,具有优异的灵敏度。采用稳定、可重复使用的传感器对片剂样品中的氨氮进行估计。因此,利用P(DLPA)MNPMCPE作为最有效的AN伏安检测传感器。
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引用次数: 0
Application Of Seeding Crystallization as a Pre-Treatment Stage for The Reduction of Scaling Tendency of Seawater Feed to Thermal Desalination Units 种子结晶作为预处理阶段在热淡化装置中降低海水进料结垢倾向的应用
Pub Date : 2021-01-01 DOI: 10.2174/1874123102115010010
Mazen N. Al-Amaireh
The fouling inhibition in seawater desalination and scale control using crystallization with calcite seeds is evaluated experimentally in this study. The growth kinetic parameters are determined experimentally, correlated and discussed at different operating conditions. Supersaturation levels represent driving force behind the growth of crystals, which is influenced directly by seawater pH values and temperatures. Results indicate that the initial pH value of seawater must be controlled to be in the range (8-9) and calcite seeds will not have the potential to start the growth process in seawater at the normal pH (7.36). The growth kinetic parameters are determined from the measured desupersaturation curves. It is found that the growth process of calcite is controlled by the surface integration step. The growth rate of calcite increases with increasing temperature and seeding ratio (up to 1 g/L), while it decreases with increasing the salinity of seawater.
本文对方解石种子结晶在海水淡化中的阻垢抑垢效果进行了实验研究。实验确定了生长动力学参数,并对不同操作条件下的生长动力学参数进行了对比和讨论。过饱和水平是晶体生长背后的驱动力,它直接受到海水pH值和温度的影响。结果表明,海水的初始pH值必须控制在(8-9)范围内,方解石种子在正常pH值(7.36)的海水中不具备启动生长过程的潜力。生长动力学参数由测得的脱饱和度曲线确定。研究发现,方解石的生长过程受表面整合步骤控制。方解石的生长速率随温度和播种比的增加而增大(可达1 g/L),随海水盐度的增加而减小。
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引用次数: 0
Potential Evaluation of PVDF/PAN Membranes for Separation of Oil from Industrial Waste PVDF/PAN膜分离工业废油的潜力评价
Pub Date : 2021-01-01 DOI: 10.2174/1874123102115010018
J. Mehta, D. Panwar, A. Metre, M. S. Bhakhar
The aim of the experiment is to characterize the Modified Membrane from PVDF/PAN and its application in removing the Emulsified oil waste from the Industry. To get the maximum separation of the emulsified oil from the waste water, composite (PVDF/PAN) membrane was prepared in the laboratory. New PVDF/PAN blend based ultrafiltration membranes were synthesized by phase inversion method. The blend membrane was treated at room temperature with aqueous sodium hydroxide solutions. The facile eco-friendly preparation of PVDF/PAN blended membrane has a wide potential for practical applications in emulsified wastewater remediation. The chemical functionality of the modified membranes was confirmed by IR spectra. For the separation of emulsified oily wastewater, the as-prepared composite (PVDF/PAN) membrane could effectively separate oil/ water emulsions with separation efficiency of above 99.8%. Unmodified membranes (A and B) showed 95.4-99.8% rejection. However, in the case of membranes C and D, oil rejection was higher for the modified membranes as compared to the unmodified membranes.
研究了聚偏氟乙烯/聚丙烯腈改性膜及其在工业废油乳化处理中的应用。为了最大限度地分离废水中的乳化油,在实验室制备了复合膜(PVDF/PAN)。采用相转化法制备了新型PVDF/PAN共混超滤膜。用氢氧化钠水溶液在室温下处理共混膜。聚偏氟乙烯/聚丙烯腈共混膜的制备工艺简便、环保,在乳化废水处理中具有广泛的应用前景。红外光谱证实了改性膜的化学功能。对于乳化含油废水的分离,所制备的复合膜(PVDF/PAN)可有效分离油水乳液,分离效率达99.8%以上。未修饰膜(A和B)的排异率为95.4-99.8%。然而,在膜C和D的情况下,与未改性的膜相比,改性膜的排油率更高。
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引用次数: 1
Electrochemical Fabrication of Poly (niacin) Modified Graphite Paste Electrode and its Application for the Detection of Riboflavin 聚烟酸修饰石墨糊电极的电化学制备及其在核黄素检测中的应用
Pub Date : 2020-12-31 DOI: 10.2174/1874123102014010090
J. G. Manjunatha, C. Raril, Hareesha Nagarajappa, M. M. Charithra, P. A. Pushpanjali, Girish Tigari, D. Ravishankar, S. C. Mallappaji, J. Gowda
Department of Chemistry, FMKMC College, Madikeri, Mangalore University Constituent College, Karnataka, India 2 Department of Chemistry, Sri Mahadeshwara Govt. First Grade College (University of Mysore), Chamarajanagar, India Department of Chemistry, Government First Grade College for Women, (Affiliated to University of Mysore), Mysuru, India Department of Chemistry, Bharathi College, Bharathi nagar, Mandya, India
印度卡纳塔克邦曼格洛尔大学组成学院maddikeri FMKMC学院化学系2印度迈索尔查玛拉贾那格尔印度政府一级女子学院化学系(附属于迈索尔大学),印度迈苏尔巴拉蒂学院化学系,印度曼迪亚巴拉蒂纳加尔
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引用次数: 10
Heat Transfer Modeling in Bone Tumour Hyperthermia Induced by Hydroxyapatite Magnetic Thermo-Seeds 羟基磷灰石磁性热种子诱导骨肿瘤热疗的传热模型
Pub Date : 2020-11-20 DOI: 10.2174/1874123102014010077
F. Fanari, L. Mariani, F. Desogus
Hyperthermia is an adjuvant oncologic thermal therapy. In the case of deep-seated bone cancers, the interstitial hyperthermia treatment can be performed using thermo-seeds, implanted biomaterial components that are able to convert external electromagnetic power into thermal one. Several magnetic biomaterials have been synthesized for thermal treatments of cancer. However, less attention has been paid to the modeling description of the therapy, especially when the bio-heat transfer process is coupled to the electromagnetic heating.
热疗是一种辅助肿瘤热疗法。对于深部骨癌,可以使用热种子进行间质热疗治疗,植入的生物材料组件能够将外部电磁功率转换为热能量。已经合成了几种用于癌症热治疗的磁性生物材料。然而,很少有人关注该疗法的建模描述,特别是当生物传热过程与电磁加热耦合时。
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引用次数: 1
Drying of Banana-Stepwise Effect in Drying Air Temperature on Drying Kinetics 香蕉干燥——干燥空气温度对干燥动力学的逐级影响
Pub Date : 2020-08-24 DOI: 10.2174/1874123102014010071
J. Mehta, D. Panwar, Smit Ghardesia, Atik Chauhan, Virajsinh V. Atodariya, Bannishikha Banerjee, A. Metre, M. S. Bhakhar
Objective: Three different varieties of banana namely Dwarf Cavendish (Ankleshwar region), Lacatan (Valia region) and Harichal (Bharuch region) were collected from the south Gujarat region, India to check the drying parameters. A pilot scale natural draft tray dryer was used for the drying experimental work.
目的:采集印度南部古吉拉特邦的矮子卡文迪什(Ankleshwar地区)、拉卡坦(Valia地区)和哈里恰尔(Harichal地区)三个不同品种的香蕉,考察其干燥参数。采用中试自然通风板式干燥机进行干燥实验。
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引用次数: 2
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The Open Chemical Engineering Journal
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