Penelitian ini merupakan penelitian eksperimental murni laboratorium pre-post test group control design. Subyek penelitian berupa 36 ekor tikus putih jantan dewasa (strain wistar Rattus norvegicus) berumur 10 minggu dengan BB 200-250 gram. Sebelum perlakuan, tikus diambil darahnya 1.5 cc untuk diukur nilai MCV dan morfologi eritrosit darah tepi. Kemudian sampel dibagi menjadi 6 kelompok diberikan perlakuan selama 45 hari dengan pemberian alkohol peroral secara terus menerus. Sesudah perlakuan, tikus diambil darahnya untuk diukur nilai MCV dan morfologi eritrosit darah tepi serta diambil femur kanan untuk pemeriksaan morfologi dan diameter normoblas sumsum tulang. Hasil penelitian menunjukkan terjadi peningkatan nilai MCV sesudah perlakuan selaras dengan semakin tingginya konsentrasi alkohol yang diberikan (p 0.000 0.05) tetapi ada kecenderungan peningkatan diameter normoblas. Pengamatan kualitatif terhadap gambaran normoblas menunjukkan hanya kelompok kontrol yang mempunyai ciri-ciri morfologi normoblas normal, sedangkan kelompok perlakuan telah mengalami perubahan morfologi sel. Kesimpulan dari penelitian ini adalah pemberian alkohol peroral secara terus menerus menyebabkan peningkatan nilai MCV tikus, perubahan morfologi eritrosit darah tepi dan normoblas sumsum tulang serta terjadi kecenderungan peningkatan diameter normoblas.
{"title":"Pengaruh Pemberian Alkohol Peroral Terhadap Nilai Mean Corpuscular Volume, Morfologi Eritrosit Darah Tepi dan Normoblas Sumsum Tulang","authors":"Rodhi Hartono, Soewono Soewono, Triana Ratnaningsih","doi":"10.31983/JLM.V1I1.5161","DOIUrl":"https://doi.org/10.31983/JLM.V1I1.5161","url":null,"abstract":"Penelitian ini merupakan penelitian eksperimental murni laboratorium pre-post test group control design. Subyek penelitian berupa 36 ekor tikus putih jantan dewasa (strain wistar Rattus norvegicus) berumur 10 minggu dengan BB 200-250 gram. Sebelum perlakuan, tikus diambil darahnya 1.5 cc untuk diukur nilai MCV dan morfologi eritrosit darah tepi. Kemudian sampel dibagi menjadi 6 kelompok diberikan perlakuan selama 45 hari dengan pemberian alkohol peroral secara terus menerus. Sesudah perlakuan, tikus diambil darahnya untuk diukur nilai MCV dan morfologi eritrosit darah tepi serta diambil femur kanan untuk pemeriksaan morfologi dan diameter normoblas sumsum tulang. Hasil penelitian menunjukkan terjadi peningkatan nilai MCV sesudah perlakuan selaras dengan semakin tingginya konsentrasi alkohol yang diberikan (p 0.000 0.05) tetapi ada kecenderungan peningkatan diameter normoblas. Pengamatan kualitatif terhadap gambaran normoblas menunjukkan hanya kelompok kontrol yang mempunyai ciri-ciri morfologi normoblas normal, sedangkan kelompok perlakuan telah mengalami perubahan morfologi sel. Kesimpulan dari penelitian ini adalah pemberian alkohol peroral secara terus menerus menyebabkan peningkatan nilai MCV tikus, perubahan morfologi eritrosit darah tepi dan normoblas sumsum tulang serta terjadi kecenderungan peningkatan diameter normoblas.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"20 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134259645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industri tahu dalam proses produksinya menghasilkan limbah cair yang menimbulkan masalah pencemaran, sehingga merusak lingkungan. Limbah cair tahu mengandung senyawa-senyawa organik sehingga menyebabkan kadar Total Suspended Solid (TSS) yang tinggi. Total Suspended Solid (TSS) yang mengendap di dasar sungai, akan membentuk lumpur yang dapat mengganggu aliran air sungai serta menyebabkan pendangkalan sungai. Mengetahui perbedaan kadar TSS pada air Sungai Nguneng sebelum dan sesudah tercemar limbah cair tahu. Penelitian observasional analitik dengan pendekatan cross sectional. Sampel yang digunakan yaitu air Sungai Nguneng sebelum dan sesudah tercemar limbah cair tahu, kemudian dilakukan pemeriksaan kadar TSS secara duplo dengan lima kali pengulangan berdasarkan hari yang berbeda. Analisa data menggunakan uji Paired Sample T-Test dengan derajat kepercayaan 95%. Rata-rata kadar TSS yang diperoleh pada air Sungai Nguneng sebelum tercemar limbah cair tahu adalah 220,4 mg/l. Rata-rata kadar TSS yang diperoleh pada air Sungai Nguneng sesudah tercemar limbah cair tahu adalah 558,4 mg/l. Uji Peired Samples T-Test dengan tingkat kesalahan 5% dan signifikasi .000 (p < 0,05). Terdapat perbedaan kadar TSS pada air Sungai Nguneng sebelum dan sesudah tercemar limbah cair tahu.
{"title":"Perbedaan Kadar Total Suspended Solid pada Air Sungai Nguneng Sebelum dan Sesudah Tercemar Limbah Cair Tahu","authors":"Dewi Yuliyanti","doi":"10.31983/jlm.v1i1.4937","DOIUrl":"https://doi.org/10.31983/jlm.v1i1.4937","url":null,"abstract":"Industri tahu dalam proses produksinya menghasilkan limbah cair yang menimbulkan masalah pencemaran, sehingga merusak lingkungan. Limbah cair tahu mengandung senyawa-senyawa organik sehingga menyebabkan kadar Total Suspended Solid (TSS) yang tinggi. Total Suspended Solid (TSS) yang mengendap di dasar sungai, akan membentuk lumpur yang dapat mengganggu aliran air sungai serta menyebabkan pendangkalan sungai. Mengetahui perbedaan kadar TSS pada air Sungai Nguneng sebelum dan sesudah tercemar limbah cair tahu. Penelitian observasional analitik dengan pendekatan cross sectional. Sampel yang digunakan yaitu air Sungai Nguneng sebelum dan sesudah tercemar limbah cair tahu, kemudian dilakukan pemeriksaan kadar TSS secara duplo dengan lima kali pengulangan berdasarkan hari yang berbeda. Analisa data menggunakan uji Paired Sample T-Test dengan derajat kepercayaan 95%. Rata-rata kadar TSS yang diperoleh pada air Sungai Nguneng sebelum tercemar limbah cair tahu adalah 220,4 mg/l. Rata-rata kadar TSS yang diperoleh pada air Sungai Nguneng sesudah tercemar limbah cair tahu adalah 558,4 mg/l. Uji Peired Samples T-Test dengan tingkat kesalahan 5% dan signifikasi .000 (p < 0,05). Terdapat perbedaan kadar TSS pada air Sungai Nguneng sebelum dan sesudah tercemar limbah cair tahu.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132558533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tuberkulosis paru adalah penyakit menular yang disebabkan oleh Mycobakterium tuberculosis, penyakit Diabetes melitus merupakan salah satu faktor resiko tersering pada penderita tuberkulosis paru, perlangsungan TB Paru–DM lebih berat dan kronis dibanding non diabetes, yang mana dapat mengakibatkan meningkatnya kerentanan terhadap bakteri tuberkulosis dan waktu pengobatan yang lama. Tujuan penelitian ini untuk mengetahui gambaran glukosa darah pada penderita tuberkulosis paru positif di UP3 Kebumen. Metode penelitian yang dilakukan termasuk jenis penelitian deskriptif. Populasi penelitian adalah semua pasien tuberkulosis paru dengan BTA positif di UP3 Kebumen tahun 2017. Sampel yang digunakan berjumlah 100 sampel, 6 sampel mempunyai kadar glukosa darah ≥ 200 mg/dl, 4 orang kadar glukosa darah antara 150 – 199 mg/dl, dan paling banyak mempunyai kadar glukosa darah antara 70 – 149 mg/dl. Kesimpulan dari penelitian ini adalah penderita tuberkulosis paru di UP3 Kebumen hanya sebagian kecil yang menderita Diabetes.
{"title":"Gambaran Kadar Glukosa Darah pada Penderita Tuberkulosis Paru dengan Bakteri Tahan Asam Positif","authors":"S. Suharyati, S. Y. D. Widiyanto","doi":"10.31983/jlm.v1i1.5180","DOIUrl":"https://doi.org/10.31983/jlm.v1i1.5180","url":null,"abstract":"Tuberkulosis paru adalah penyakit menular yang disebabkan oleh Mycobakterium tuberculosis, penyakit Diabetes melitus merupakan salah satu faktor resiko tersering pada penderita tuberkulosis paru, perlangsungan TB Paru–DM lebih berat dan kronis dibanding non diabetes, yang mana dapat mengakibatkan meningkatnya kerentanan terhadap bakteri tuberkulosis dan waktu pengobatan yang lama. Tujuan penelitian ini untuk mengetahui gambaran glukosa darah pada penderita tuberkulosis paru positif di UP3 Kebumen. Metode penelitian yang dilakukan termasuk jenis penelitian deskriptif. Populasi penelitian adalah semua pasien tuberkulosis paru dengan BTA positif di UP3 Kebumen tahun 2017. Sampel yang digunakan berjumlah 100 sampel, 6 sampel mempunyai kadar glukosa darah ≥ 200 mg/dl, 4 orang kadar glukosa darah antara 150 – 199 mg/dl, dan paling banyak mempunyai kadar glukosa darah antara 70 – 149 mg/dl. Kesimpulan dari penelitian ini adalah penderita tuberkulosis paru di UP3 Kebumen hanya sebagian kecil yang menderita Diabetes.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126178045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eko Naning Sofyanita, Roni Afriansya, Nur Indah Palupi
Kidneys are part of the body that has an important role. One of the functions of the kidney is the production of erythropoietin. Erythropoietin stimulates the production of red blood cells. People or patients who have kidney problems can cause anemia. This study aims to determine the relationship between hemoglobin levels and blood creatinine levels in patients with chronic kidney disease after receiving a transfusion. Blood creatinine levels in this study were used as an index to measure kidney function. The study was conducted at the Wira Tamtama Hospital Semarang by taking data on 20 patients in 2020 with chronic kidney disease and taking data on hemoglobin (cut-off 12 g/dL) and serum creatinine (cut-off 1.5 mg/dL). The relationship between the two was calculated by chi-square test and found 80% of patients with low hemoglobin in patients with high creatinine levels and 0% of patients with low hemoglobin in patients with normal creatinine levels (p=0.040). There is a risk of decreased hemoglobin levels (OR = 3,442) in patients with high creatinine levels. It was concluded that there was a significant relationship between hemoglobin levels and blood creatinine levels and patients with high creatinine levels tended to be at risk of anemia.
{"title":"Correlation Of Hemoglobin And Blood Creatinine Levels In Chronic Kidney Disease Patients Post Repeated Transfusion","authors":"Eko Naning Sofyanita, Roni Afriansya, Nur Indah Palupi","doi":"10.31983/jlm.v2i2.7030","DOIUrl":"https://doi.org/10.31983/jlm.v2i2.7030","url":null,"abstract":"Kidneys are part of the body that has an important role. One of the functions of the kidney is the production of erythropoietin. Erythropoietin stimulates the production of red blood cells. People or patients who have kidney problems can cause anemia. This study aims to determine the relationship between hemoglobin levels and blood creatinine levels in patients with chronic kidney disease after receiving a transfusion. Blood creatinine levels in this study were used as an index to measure kidney function. The study was conducted at the Wira Tamtama Hospital Semarang by taking data on 20 patients in 2020 with chronic kidney disease and taking data on hemoglobin (cut-off 12 g/dL) and serum creatinine (cut-off 1.5 mg/dL). The relationship between the two was calculated by chi-square test and found 80% of patients with low hemoglobin in patients with high creatinine levels and 0% of patients with low hemoglobin in patients with normal creatinine levels (p=0.040). There is a risk of decreased hemoglobin levels (OR = 3,442) in patients with high creatinine levels. It was concluded that there was a significant relationship between hemoglobin levels and blood creatinine levels and patients with high creatinine levels tended to be at risk of anemia.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126562297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The cutting stage is the network manufacturing stage which needs to be considered the thickness scale. The standard scale that is commonly used is 2-7 µm, while the thickness of 5 µm which is used as a standard for cutting the thickness of the liver tissue shows that the cell is good for cutting liver tissue in mice (Mus musculus). Mice have many advantages, while the liver organ is one of the organs that are often used in research. The aim of this study was to describe the microscopic quality of liver preparations of mice (Mus musculus) by cutting tissue thickness of 2 µm, 5 µm and 8 µm. This type of research includes experimental research with descriptive research criteria. The study design used a purposive sampling study approach. The results of the quality of microscopic images of mice tissue (Mus musculus) at a thickness of 2 µm there were 12% not good, 20% not good and 68% good. The thickness of 5 µm is 100% good, while the thickness of 8 µm is 8%, the preparation is not good, 36% is not good, and 56% is good. The conclusions of this study were microscopic tissue mice (Mus musculus) preparations with good quality 68%, 8 µm 56%, and 100% at a thickness of 5 µm.
{"title":"Microscopic Quality Profile of Mice Liver (Mus musculus) with 2µm, 5µm and 8µm Thickness Sections","authors":"Mircha Restiana Elen","doi":"10.31983/jlm.v4i2.8483","DOIUrl":"https://doi.org/10.31983/jlm.v4i2.8483","url":null,"abstract":"The cutting stage is the network manufacturing stage which needs to be considered the thickness scale. The standard scale that is commonly used is 2-7 µm, while the thickness of 5 µm which is used as a standard for cutting the thickness of the liver tissue shows that the cell is good for cutting liver tissue in mice (Mus musculus). Mice have many advantages, while the liver organ is one of the organs that are often used in research. The aim of this study was to describe the microscopic quality of liver preparations of mice (Mus musculus) by cutting tissue thickness of 2 µm, 5 µm and 8 µm. This type of research includes experimental research with descriptive research criteria. The study design used a purposive sampling study approach. The results of the quality of microscopic images of mice tissue (Mus musculus) at a thickness of 2 µm there were 12% not good, 20% not good and 68% good. The thickness of 5 µm is 100% good, while the thickness of 8 µm is 8%, the preparation is not good, 36% is not good, and 56% is good. The conclusions of this study were microscopic tissue mice (Mus musculus) preparations with good quality 68%, 8 µm 56%, and 100% at a thickness of 5 µm.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133059762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV cases in Jepara District in recent years have demanded the handling of several aspects simultaneously including the Blood Transfusion Unit (BTU). HIV can be transmitted through blood transfusion or other blood products. BTU of PMI Jepara Regency carries out recruitment of voluntary donor from Jepara society. The HIV examination as part of an IMLTD screening test is done for safety of donor blood. The HIV examination in all donor blood uses rapid and elisa method. Examination results are stated as reactive and non reactive. Research objective to find out the description of HIV examination results in donor blood at the BTU of PMI Kabupaten Jepara in 2019. Research method the research type was descriptive using records of donor data at BTU of PMI Kabupaten Jepara in 2019. The examination results of reactive HIV in 12 donor blood (0,08%). non-reactive blood donor of HIV in age groups 18 years, 18-24, 25-44, 45-59, and ≥ 60 years respectively 9,55%, 22,39%, 51,75%, 16,01% and 0,21%. Reactive HIV in age groups 18-24, 25-44, and 45-59 years were 0,034%, 0,034%, and 0,13%. Non-reactive HIV in men 68,22% and in women 31,70%. Reactive HIV in men 0,07%, and women 0,01%. Non-reactive HIV in voluntary donor blood was 99,779% and substitute donor was 0,127%. HIV of reactive voluntary donor blood was 0,074%, and substitute donor was 0,007%. HIV filter test is indispensable for blood safety because the age, gender and blood type of donors have the potential for reactive HIV.
近年来,杰帕拉地区的艾滋病毒病例需要同时处理几个方面,包括输血单位。艾滋病毒可以通过输血或其他血液制品传播。PMI耶帕拉摄政的BTU负责从耶帕拉社会招募自愿捐助者。艾滋病毒检查作为IMLTD筛选试验的一部分,是为了献血者的血液安全而进行的。所有献血者的HIV检测均采用快速elisa法。检查结果分为反应性和非反应性。研究目的了解2019年帕帕拉医院BTU献血者血液HIV检测结果的描述。研究方法:研究类型为描述性,使用2019年PMI Kabupaten Jepara BTU的供体数据记录。献血者血液HIV阳性12例(0.08%)。18岁、18-24岁、25-44岁、45-59岁和≥60岁年龄组的无反应性献血者HIV感染率分别为9.55%、22.39%、51.75%、16.01%和0.21%。18-24岁、25-44岁和45-59岁年龄组的HIV反应性感染率分别为0.034%、0.034%和0.13%。男性无反应性艾滋病毒感染率为68.22%,女性为31.70%。男性反应性HIV感染率为0.07%,女性为0.01%。自愿献血者血液中无反应性HIV为99779%,替代献血者为0127%。反应性献血者的HIV感染率为0.074 %,替代献血者的HIV感染率为0.007%。由于献血者的年龄、性别和血型有可能感染反应性艾滋病毒,因此艾滋病毒过滤检测对于血液安全是必不可少的。
{"title":"Gambaran Hasil Pemeriksaan HIV pada Darah Donor","authors":"B. Triatmojo","doi":"10.31983/jlm.v2i1.7032","DOIUrl":"https://doi.org/10.31983/jlm.v2i1.7032","url":null,"abstract":"HIV cases in Jepara District in recent years have demanded the handling of several aspects simultaneously including the Blood Transfusion Unit (BTU). HIV can be transmitted through blood transfusion or other blood products. BTU of PMI Jepara Regency carries out recruitment of voluntary donor from Jepara society. The HIV examination as part of an IMLTD screening test is done for safety of donor blood. The HIV examination in all donor blood uses rapid and elisa method. Examination results are stated as reactive and non reactive. Research objective to find out the description of HIV examination results in donor blood at the BTU of PMI Kabupaten Jepara in 2019. Research method the research type was descriptive using records of donor data at BTU of PMI Kabupaten Jepara in 2019. The examination results of reactive HIV in 12 donor blood (0,08%). non-reactive blood donor of HIV in age groups 18 years, 18-24, 25-44, 45-59, and ≥ 60 years respectively 9,55%, 22,39%, 51,75%, 16,01% and 0,21%. Reactive HIV in age groups 18-24, 25-44, and 45-59 years were 0,034%, 0,034%, and 0,13%. Non-reactive HIV in men 68,22% and in women 31,70%. Reactive HIV in men 0,07%, and women 0,01%. Non-reactive HIV in voluntary donor blood was 99,779% and substitute donor was 0,127%. HIV of reactive voluntary donor blood was 0,074%, and substitute donor was 0,007%. HIV filter test is indispensable for blood safety because the age, gender and blood type of donors have the potential for reactive HIV.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"447 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123625541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heavy metal cadmium (Cd) is one of the environmental contaminants harmful and accumulates in the tissues of living creatures. One example of an exposed kamium can ditemukann in smokers. Cadmium contained in cigarette smoke enters through the inhalation then the cadmium is transported in blood and excreted through urine. The levels of cadmium in the body which exceeds the Value of the Threshold can cause damage to the kidneys and liver.The purpose of this study was to determine the picture content of cadmium in the urine of active smokers. Methods this study is no Study of this descriptive type of case report. The sample used comes from the 12 research subjects who are willing to be taken a sample of her urine. The inspection method used is Atomic Absorption Spectrophotometer (AAS).The results of this study are from 12 samples of active smokers in RT 01/I Sendangguwo South results obtained for cadmium content 0,000185 mg/L below Threshold Limit Values.Conclusion this study is an overview of the levels of cadmium in the urine on the whole subject of research under the Threshold Value.
{"title":"Profile of Cadmium (Cd) Levels in Urine in Active Smokers","authors":"R. M. Sari","doi":"10.31983/jlm.v2i1.6982","DOIUrl":"https://doi.org/10.31983/jlm.v2i1.6982","url":null,"abstract":"Heavy metal cadmium (Cd) is one of the environmental contaminants harmful and accumulates in the tissues of living creatures. One example of an exposed kamium can ditemukann in smokers. Cadmium contained in cigarette smoke enters through the inhalation then the cadmium is transported in blood and excreted through urine. The levels of cadmium in the body which exceeds the Value of the Threshold can cause damage to the kidneys and liver.The purpose of this study was to determine the picture content of cadmium in the urine of active smokers. Methods this study is no Study of this descriptive type of case report. The sample used comes from the 12 research subjects who are willing to be taken a sample of her urine. The inspection method used is Atomic Absorption Spectrophotometer (AAS).The results of this study are from 12 samples of active smokers in RT 01/I Sendangguwo South results obtained for cadmium content 0,000185 mg/L below Threshold Limit Values.Conclusion this study is an overview of the levels of cadmium in the urine on the whole subject of research under the Threshold Value.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"601 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132686747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Until now, tuberculosis is still a public health problem in the world. Tuberculosis is a dangerous infectious disease, the healing process also takes a long time. Acid-fast bacilli examination is an examination to determine the presence or absence of Mycobacterium tuberculosis bacteria. The factors that influence Tuberculosis patients are age, gender, education and occupation. The purpose is to knowing the description of AFB positivity in patients with clinical diagnosis of pulmonary tuberculosis at Balkesmas Semarang in 2020. This research was an observational study with descriptive research criteria through a retrospective approach. Results from 656 patients with clinical diagnosis of tuberculosis who underwent acid-fast bacilli examination, 220 patients (33.5%) were found positive and acid-fast bacilli were negative (64.5%). The results of the examination of acid-fast bacilli were positive with a scanty positivity degree of 3 patients (1.4%), acid-fast bacilli (+1) were 71 patients (32.3%), (+2) were 83 patients (37.7%), (+3) as many as 63 patients (28.6%). Based on the category of age 0-14 years as many as 1 patient (0.5%), 15-34 years as many as 78 patients (35.5%), 35-54 years as many as 96 patients (43.6%), 55-74 years as many as 44 patients (20%), 75 years as many as 1 patient (0.5%). Based on gender, there were 123 patients (56%) male and 97 female patients (44%). Conclusion the results of the examination of acid-fast bacilli were positive with a scanty positivity rate of 3 patients (1.4%), acid-fast bacilli (+1) 71 patients (32.3%), (+2) 83 patients (37.7%), (+3) 63 patients (28.5%). Based on gender with positive acid-fast bacilli, there were 123 male patients (56%) while female 97 patients (44%). Age with the most positive acid-fast bacilli results in the range 0–14 years 1 patient (0.5%), 15–34 years 78 patients (35.5%), 35-54 years 96 patients (43.6%), 55 –74 years.
{"title":"Positive Profile of Acid-fast bacilli in Patients with Clinical Diagnosis of Pulmonary Tuberculosis at the Semarang Public Health Center","authors":"Fitriani Kahar, P. Novitasari, I. Irnawati","doi":"10.31983/jlm.v4i2.8552","DOIUrl":"https://doi.org/10.31983/jlm.v4i2.8552","url":null,"abstract":"Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Until now, tuberculosis is still a public health problem in the world. Tuberculosis is a dangerous infectious disease, the healing process also takes a long time. Acid-fast bacilli examination is an examination to determine the presence or absence of Mycobacterium tuberculosis bacteria. The factors that influence Tuberculosis patients are age, gender, education and occupation. The purpose is to knowing the description of AFB positivity in patients with clinical diagnosis of pulmonary tuberculosis at Balkesmas Semarang in 2020. This research was an observational study with descriptive research criteria through a retrospective approach. Results from 656 patients with clinical diagnosis of tuberculosis who underwent acid-fast bacilli examination, 220 patients (33.5%) were found positive and acid-fast bacilli were negative (64.5%). The results of the examination of acid-fast bacilli were positive with a scanty positivity degree of 3 patients (1.4%), acid-fast bacilli (+1) were 71 patients (32.3%), (+2) were 83 patients (37.7%), (+3) as many as 63 patients (28.6%). Based on the category of age 0-14 years as many as 1 patient (0.5%), 15-34 years as many as 78 patients (35.5%), 35-54 years as many as 96 patients (43.6%), 55-74 years as many as 44 patients (20%), 75 years as many as 1 patient (0.5%). Based on gender, there were 123 patients (56%) male and 97 female patients (44%). Conclusion the results of the examination of acid-fast bacilli were positive with a scanty positivity rate of 3 patients (1.4%), acid-fast bacilli (+1) 71 patients (32.3%), (+2) 83 patients (37.7%), (+3) 63 patients (28.5%). Based on gender with positive acid-fast bacilli, there were 123 male patients (56%) while female 97 patients (44%). Age with the most positive acid-fast bacilli results in the range 0–14 years 1 patient (0.5%), 15–34 years 78 patients (35.5%), 35-54 years 96 patients (43.6%), 55 –74 years.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116716065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nasopharyngeal cancer (NPC) is the 4th most common malignancy in Indonesia, after breast, cervical and lung cancer. The risk factors for this cancer are Epstein-Barr virus, gender, race, adult age 30-50 years, family history, drinking alcohol and smoking. The prevalence of NPC in Indonesia is 6.2/100,000, with nearly 13,000 new cases, but this is a small proportion that has been documented. Adham et al (2012) reported that NPC is the most common head and neck cancer (28.4%), with a male-female ratio of 2:4 and is endemic to the island of Java. The existence of knowledge about NPC starting from prevention, early detection, appropriate treatment will be able to help overcome problems caused by nasopharyngeal cancer. Early detection is very important. If NPC is found at an early stage, the cure rate is quite high, reaching 90%. The purpose of this study was to find out whether there were gas station workers in Semarang City who experienced NPC. This study used an analytic survey method with a cross-sectional approach. The results of the study of 20 Semarang City Gas Station officers found that the characteristics based on age were the most in the range 31-50, namely 70%. Characteristics based on gender of the 20 gas station attendants are all male (100%). Characteristics based on length of service are 1 - 10 years (35%), 11 - 20 years (35%) and 21 - 30 years (30%) respectively. Characteristics based on smoking history, 55% of respondents smoked and 45% did not smoke. And the NPC examination results of all respondents (100%) were NPC negative.
{"title":"Deteksi Karsinoma Nasofaring Mengunakan Rapid Test Uji Imunokromatografi pada Petugas SPBU","authors":"Roni Afriansya, U. Rosidah, Eko Naning Sofyanita","doi":"10.31983/jlm.v5i1.9337","DOIUrl":"https://doi.org/10.31983/jlm.v5i1.9337","url":null,"abstract":"Nasopharyngeal cancer (NPC) is the 4th most common malignancy in Indonesia, after breast, cervical and lung cancer. The risk factors for this cancer are Epstein-Barr virus, gender, race, adult age 30-50 years, family history, drinking alcohol and smoking. The prevalence of NPC in Indonesia is 6.2/100,000, with nearly 13,000 new cases, but this is a small proportion that has been documented. Adham et al (2012) reported that NPC is the most common head and neck cancer (28.4%), with a male-female ratio of 2:4 and is endemic to the island of Java. The existence of knowledge about NPC starting from prevention, early detection, appropriate treatment will be able to help overcome problems caused by nasopharyngeal cancer. Early detection is very important. If NPC is found at an early stage, the cure rate is quite high, reaching 90%. The purpose of this study was to find out whether there were gas station workers in Semarang City who experienced NPC. This study used an analytic survey method with a cross-sectional approach. The results of the study of 20 Semarang City Gas Station officers found that the characteristics based on age were the most in the range 31-50, namely 70%. Characteristics based on gender of the 20 gas station attendants are all male (100%). Characteristics based on length of service are 1 - 10 years (35%), 11 - 20 years (35%) and 21 - 30 years (30%) respectively. Characteristics based on smoking history, 55% of respondents smoked and 45% did not smoke. And the NPC examination results of all respondents (100%) were NPC negative.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127148485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
TB patients who do not adhere to OAT treatment can lead to resistance and become MDR-TB and add to the burden of TB management globally. TB control programs including microscopic sputum examination are important for diagnosis, evaluation, follow-up treatment, and follow-up. The results of the sputum examination used the IUATLD scale as an interpretation of the results and the reporting was negative, scanty, positive one, positive two, and positive three according to the number of TB germs found. The results of the sputum examination to determine the classification of the patient, the decision to start treatment, and the patient's recovery. At the step of treatment for MDR-TB patients, the results of sputum examination are an indicator to determine the success rate of treatment which is marked by the conversion of BTA. Research objectives is to determine the description of the results of sputum examination in Multidrug-Resistant Tuberculosis (MDR-TB) patients at the Kendal District Health Center. Research methods is observational research with descriptive research criteria through a cross sectional approach. Respondents of the study were multidrug-resistant tuberculosis (MDR-TB) patients from three health centers in Kendal district with the highest case prevalence. The study respondents were 7 MDR-TB patients. All study respondents, totaling 7 MDR-TB patients (100%), were included in the advanced step of treatment and showed negative sputum examination results. All study respondents (100%) showed that the results of microscopic sputum examination were negative, which means that BTA conversion occurred at the advanced treatment step.
{"title":"Profile of Sputum Examination Results in Multidrug-Resistant Tuberculosis (MDR-TB) Patients","authors":"Alisa Khodrun Nadza, Surati Surati","doi":"10.31983/jlm.v4i2.8526","DOIUrl":"https://doi.org/10.31983/jlm.v4i2.8526","url":null,"abstract":"TB patients who do not adhere to OAT treatment can lead to resistance and become MDR-TB and add to the burden of TB management globally. TB control programs including microscopic sputum examination are important for diagnosis, evaluation, follow-up treatment, and follow-up. The results of the sputum examination used the IUATLD scale as an interpretation of the results and the reporting was negative, scanty, positive one, positive two, and positive three according to the number of TB germs found. The results of the sputum examination to determine the classification of the patient, the decision to start treatment, and the patient's recovery. At the step of treatment for MDR-TB patients, the results of sputum examination are an indicator to determine the success rate of treatment which is marked by the conversion of BTA. Research objectives is to determine the description of the results of sputum examination in Multidrug-Resistant Tuberculosis (MDR-TB) patients at the Kendal District Health Center. Research methods is observational research with descriptive research criteria through a cross sectional approach. Respondents of the study were multidrug-resistant tuberculosis (MDR-TB) patients from three health centers in Kendal district with the highest case prevalence. The study respondents were 7 MDR-TB patients. All study respondents, totaling 7 MDR-TB patients (100%), were included in the advanced step of treatment and showed negative sputum examination results. All study respondents (100%) showed that the results of microscopic sputum examination were negative, which means that BTA conversion occurred at the advanced treatment step.","PeriodicalId":232833,"journal":{"name":"Jaringan Laboratorium Medis","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130895833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}