Pub Date : 2024-07-30DOI: 10.30574/wjbphs.2024.19.1.0444
Lalit Sharma, Navneet Mehan, Ritika Chouhan, Suman Anjali, Vaibhav Kumar, KM Rekha, Kunal Kumar, Naman Kumar
Human nails are not only beautiful and protective, but they may also be utilized as a vehicle for drug delivery, particularly in the treatment of nail disorders such as psoriasis and onychomycosis. Even though nails develop at a somewhat moderate rate, their highly keratinized structure presents unique opportunities and challenges for medication penetration. Achieving therapeutic doses might be difficult even with topical pharmaceutical delivery, which offers advantages like non-invasiveness and customized effect. Many physical and chemical methods, such as acid etching and permeation enhancers, have been studied to improve drug penetration. It has recently been demonstrated that nail lacquers have potential for effectively delivering medication through the nails. Nail anatomy, common nail diseases, nail medication administration methods, and the advantages and disadvantages of nail lacquers are all covered in this overview. In addition, it discusses factors influencing drug diffusion through nails, draws comparisons between topical nail lacquers and oral antifungal medications, and looks at recent studies and patents on the topic. Future prospects for transungual medicine administration are promising, thanks to innovations such as photodynamic therapy and water-based lacquers. To fully realize the promise of this distribution method, more research is necessary.
{"title":"Current review on nail drug delivery system and their future perspectives","authors":"Lalit Sharma, Navneet Mehan, Ritika Chouhan, Suman Anjali, Vaibhav Kumar, KM Rekha, Kunal Kumar, Naman Kumar","doi":"10.30574/wjbphs.2024.19.1.0444","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0444","url":null,"abstract":"Human nails are not only beautiful and protective, but they may also be utilized as a vehicle for drug delivery, particularly in the treatment of nail disorders such as psoriasis and onychomycosis. Even though nails develop at a somewhat moderate rate, their highly keratinized structure presents unique opportunities and challenges for medication penetration. Achieving therapeutic doses might be difficult even with topical pharmaceutical delivery, which offers advantages like non-invasiveness and customized effect. Many physical and chemical methods, such as acid etching and permeation enhancers, have been studied to improve drug penetration. It has recently been demonstrated that nail lacquers have potential for effectively delivering medication through the nails. Nail anatomy, common nail diseases, nail medication administration methods, and the advantages and disadvantages of nail lacquers are all covered in this overview. In addition, it discusses factors influencing drug diffusion through nails, draws comparisons between topical nail lacquers and oral antifungal medications, and looks at recent studies and patents on the topic. Future prospects for transungual medicine administration are promising, thanks to innovations such as photodynamic therapy and water-based lacquers. To fully realize the promise of this distribution method, more research is necessary.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"10 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/wjbphs.2024.19.1.0392
Venu A.S, Uday Kumar Rao, Rangappa S Ashi
Background: The Internet has developed into one of man's most important tools for information, employment possibilities, education, entertainment, social media, and networking, and it is progressively becoming an integral part of our daily lives. Objectives: To assess prevalence of internet addiction and its impact on socio educational area among students at selected high schools of urban areas of Davangere. Methodology: A quantitative approach with descriptive survey research design was adopted for the study. The samples from the selected high schools of urban areas were selected using probability multistage random sampling technique. The sample consisted of 200high school students. A Internet addiction test developed by Dr. Young was used to measure the internet addiction and questionnaire on Impact of internet addiction on socio educational area was used to measure impact. Results: The study result reveal that, internet addiction mean internet addiction score was 34.24, median was 34.50, mode was 25, standard deviation 11.95 and range score was 1-75. Majority 82(41%) were not had internet addiction, 83(41.5%) were had mild addiction and least 35(17.5%) of participant was had moderate level of internet addiction. With respect to impact of internet addiction on socio educational area, majority 48(43.63%) were had mild impact, 38(34.54%) were had moderate impacts and least 32(29.09%) of participants were not had impact on socio educational area. The levels of internet addiction of participants of urban area are found to be statistically significant at 0.05 levels for gender, occupation of mothers and time spent daily on internet Conclusion: The study can help policymakers to understand the burden of internet addiction among adolescent students and can make necessary changes in the education system.
{"title":"Prevalence of internet addiction and its impact on socio educational area among students of selected high schools at urban areas of Davangere, Karnataka","authors":"Venu A.S, Uday Kumar Rao, Rangappa S Ashi","doi":"10.30574/wjbphs.2024.19.1.0392","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0392","url":null,"abstract":"Background: The Internet has developed into one of man's most important tools for information, employment possibilities, education, entertainment, social media, and networking, and it is progressively becoming an integral part of our daily lives. Objectives: To assess prevalence of internet addiction and its impact on socio educational area among students at selected high schools of urban areas of Davangere. Methodology: A quantitative approach with descriptive survey research design was adopted for the study. The samples from the selected high schools of urban areas were selected using probability multistage random sampling technique. The sample consisted of 200high school students. A Internet addiction test developed by Dr. Young was used to measure the internet addiction and questionnaire on Impact of internet addiction on socio educational area was used to measure impact. Results: The study result reveal that, internet addiction mean internet addiction score was 34.24, median was 34.50, mode was 25, standard deviation 11.95 and range score was 1-75. Majority 82(41%) were not had internet addiction, 83(41.5%) were had mild addiction and least 35(17.5%) of participant was had moderate level of internet addiction. With respect to impact of internet addiction on socio educational area, majority 48(43.63%) were had mild impact, 38(34.54%) were had moderate impacts and least 32(29.09%) of participants were not had impact on socio educational area. The levels of internet addiction of participants of urban area are found to be statistically significant at 0.05 levels for gender, occupation of mothers and time spent daily on internet Conclusion: The study can help policymakers to understand the burden of internet addiction among adolescent students and can make necessary changes in the education system.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"16 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/wjbphs.2024.19.1.0400
Kimberly Craig, Reshma Persaud
Throughout history, plants have been used for their medicinal properties due to their ability to produce biochemical compounds. However, the safe use of these plants is a cause for concern due to only some species being medically tested and regulated. This research has utilised existing published information to provide a review which could serve as a global data resource to lend support to medical research. Hyde Park Zoo consists of ninety-nine (99) species of plants belonging to twenty (20) families of which eight (8) species of the decorative flowering plants were found to have medicinal properties based on existing literature. All eight (8) species were found to have antibacterial properties while three (3) species were found to have antifungal properties. Yellow Bellflower (Allamanda cathartica) was the only species noted to have antiviral properties while two (2) species have anticancer properties. Two (2) species aid with circulatory issues and one (1) species aids with arthritis. Hungarian Rose (Rosa gallica var) was noted to have psychotherapeutic effects aiding with depression through aromatherapy.
{"title":"A narrative review of pharmacological and phytochemical properties of decorative flowering plants at Hyde Park Zoo Sanctuary and Tropical Gardens Inc., Guyana","authors":"Kimberly Craig, Reshma Persaud","doi":"10.30574/wjbphs.2024.19.1.0400","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0400","url":null,"abstract":"Throughout history, plants have been used for their medicinal properties due to their ability to produce biochemical compounds. However, the safe use of these plants is a cause for concern due to only some species being medically tested and regulated. This research has utilised existing published information to provide a review which could serve as a global data resource to lend support to medical research. Hyde Park Zoo consists of ninety-nine (99) species of plants belonging to twenty (20) families of which eight (8) species of the decorative flowering plants were found to have medicinal properties based on existing literature. All eight (8) species were found to have antibacterial properties while three (3) species were found to have antifungal properties. Yellow Bellflower (Allamanda cathartica) was the only species noted to have antiviral properties while two (2) species have anticancer properties. Two (2) species aid with circulatory issues and one (1) species aids with arthritis. Hungarian Rose (Rosa gallica var) was noted to have psychotherapeutic effects aiding with depression through aromatherapy.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"2 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The primary aim of the study was to enhance the dissolution rate of fenofibrate, a poorly soluble drug classified under BCS class II. To achieve this, solid dispersions were formulated using the dropping method with polyethylene glycol (PEG) 4000 and PEG 6000 at ratios of 1:1 and 1:2. These formulations were encapsulated and subjected to various evaluations, including solubility tests, assays, FTIR, X-ray diffraction (XRD), differential scanning calorimetry (DSC), and in-vitro dissolution studies. The most effective formulation was then compared to a commercially available product. The formulation identified as D4, which utilized PEG 6000 at a 1:2 ratio via the dropping method, exhibited the highest solubility at 0.678 ± 0.07 mg/ml, a significant improvement over the pure drug's solubility of 0.018 mg/ml. The assay of D4 showed 98.14 ± 12%, with a practical yield of 95.25 ± 0.17%. In vitro dissolution testing revealed that the solid dispersions released the drug within 60 minutes, while the D4 formulation achieved a release of 99.10 ± 0.18% in just 30 minutes. This performance was notably superior to the pure drug, which had a release rate of 27.38 ± 0.10% in 60 minutes, and comparable to the marketed micronized fenofibrate capsule (Lipicard), which had a release rate of 93.91 ± 0.12% in 30 minutes. FTIR analysis indicated no interaction between the drug and the excipients, while XRD and DSC studies confirmed that the drug in the solid dispersion was in an amorphous state. The optimized formulations demonstrated stability over time. Thus, employing the dropping method with a minimal carrier ratio of 1:2 significantly improved the drug release profile, making it comparable to the micronized fenofibrate (Lipicard).
{"title":"Formulation of fenofibrate capsules by dropping method using PEG 6000 and PEG 4000 to enhance solubility","authors":"Gowtham Mandadapu, Prachetha Kolli, Kurra Venkata Gopaiah, Ramya Teja Medarametla, G. Rajesh","doi":"10.30574/wjbphs.2024.19.1.0409","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0409","url":null,"abstract":"The primary aim of the study was to enhance the dissolution rate of fenofibrate, a poorly soluble drug classified under BCS class II. To achieve this, solid dispersions were formulated using the dropping method with polyethylene glycol (PEG) 4000 and PEG 6000 at ratios of 1:1 and 1:2. These formulations were encapsulated and subjected to various evaluations, including solubility tests, assays, FTIR, X-ray diffraction (XRD), differential scanning calorimetry (DSC), and in-vitro dissolution studies. The most effective formulation was then compared to a commercially available product. The formulation identified as D4, which utilized PEG 6000 at a 1:2 ratio via the dropping method, exhibited the highest solubility at 0.678 ± 0.07 mg/ml, a significant improvement over the pure drug's solubility of 0.018 mg/ml. The assay of D4 showed 98.14 ± 12%, with a practical yield of 95.25 ± 0.17%. In vitro dissolution testing revealed that the solid dispersions released the drug within 60 minutes, while the D4 formulation achieved a release of 99.10 ± 0.18% in just 30 minutes. This performance was notably superior to the pure drug, which had a release rate of 27.38 ± 0.10% in 60 minutes, and comparable to the marketed micronized fenofibrate capsule (Lipicard), which had a release rate of 93.91 ± 0.12% in 30 minutes. FTIR analysis indicated no interaction between the drug and the excipients, while XRD and DSC studies confirmed that the drug in the solid dispersion was in an amorphous state. The optimized formulations demonstrated stability over time. Thus, employing the dropping method with a minimal carrier ratio of 1:2 significantly improved the drug release profile, making it comparable to the micronized fenofibrate (Lipicard).","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"10 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/wjbphs.2024.19.1.0404
Malika Jain, Monalisa Nayak
This study investigates the influence of adult attachment styles on self-esteem levels among young Indian adults. Drawing from the Collins Adult Attachment Scale and Rosenberg Self-Esteem Scale, data was collected via online surveys administered to a convenience sample of 150 participants. The research aims to discern how attachment styles—secure, preoccupied, dismissive, and fearful—affect self-esteem perceptions. Significant findings from ANOVA and Tukey HSD tests reveal distinct patterns among attachment styles: individuals with secure attachment display the highest self-esteem, followed by preoccupied, dismissive, and fearful attachment styles, in descending order. The study underscores the importance of understanding the intricate interplay between attachment orientations and self-esteem development, shedding light on how these psychological constructs shape individuals' perceptions of themselves. Furthermore, the findings contribute to the growing body of literature on adult attachment and its implications for mental health and well-being. These insights have the potential to inform therapeutic interventions aimed at bolstering self-esteem and fostering secure attachment relationships among young adults in diverse cultural contexts
{"title":"To explore the effect of adult attachment styles on levels of self-esteem among young Indian adults","authors":"Malika Jain, Monalisa Nayak","doi":"10.30574/wjbphs.2024.19.1.0404","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0404","url":null,"abstract":"This study investigates the influence of adult attachment styles on self-esteem levels among young Indian adults. Drawing from the Collins Adult Attachment Scale and Rosenberg Self-Esteem Scale, data was collected via online surveys administered to a convenience sample of 150 participants. The research aims to discern how attachment styles—secure, preoccupied, dismissive, and fearful—affect self-esteem perceptions. Significant findings from ANOVA and Tukey HSD tests reveal distinct patterns among attachment styles: individuals with secure attachment display the highest self-esteem, followed by preoccupied, dismissive, and fearful attachment styles, in descending order. The study underscores the importance of understanding the intricate interplay between attachment orientations and self-esteem development, shedding light on how these psychological constructs shape individuals' perceptions of themselves. Furthermore, the findings contribute to the growing body of literature on adult attachment and its implications for mental health and well-being. These insights have the potential to inform therapeutic interventions aimed at bolstering self-esteem and fostering secure attachment relationships among young adults in diverse cultural contexts","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"6 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/wjbphs.2024.19.1.0397
Kalash Dwivedi, Botirova Nigina Akram qizi, Muhammed Sinan Cheelatta
Background: Hypertension (HTN) and diabetes mellitus (DM) are prevalent chronic conditions associated with significant morbidity and mortality not only in the Uzbekistan but in the whole globe . Understanding their conjoined impact on blood sugar levels, particularly about gender-specific differences, is crucial for optimizing patient management strategies. Aim: This study aims to investigate the effect of HTN on blood sugar levels in patients with and without DM, focusing on gender-specific variations. Method: A sample of 160 patients from the Tashkent Polyclinic was categorized based on Hypertension and diabetes status. Blood sugar levels were measured using a glucometer, and statistical analyses, including t-tests, were conducted to compare blood sugar levels between groups with the help of excel . Result: Significant variations in blood sugar levels were noted between patients with both HTN and DM and those with only HTN. Gender-specific differences or variance were noted, with females exhibiting higher blood sugar levels than males, particularly in the presence of both conditions HTN and DM. Conclusion: The findings give the importance of personalized management strategies for hypertensive patients with coexisting DM, also considering gender-specific factors. Further research is warranted to elucidate the underlying mechanisms driving these differences and optimize clinical outcomes.
背景：高血压（HTN）和糖尿病（DM）是普遍存在的慢性疾病，不仅在乌兹别克斯坦，而且在全球都与严重的发病率和死亡率有关。了解它们对血糖水平的共同影响，尤其是性别差异，对于优化患者管理策略至关重要。目的：本研究旨在调查高血压对糖尿病患者和非糖尿病患者血糖水平的影响，重点关注性别差异。研究方法：根据高血压和糖尿病状态对塔什干综合医院的 160 名患者进行分类。使用血糖仪测量血糖水平，并借助 excel 进行统计分析，包括 t 检验，以比较各组间的血糖水平。结果同时患有高血压和糖尿病的患者与仅患有高血压的患者之间的血糖水平存在显著差异。研究还发现了性别差异，女性的血糖水平高于男性，尤其是同时患有高血压和糖尿病的患者。结论研究结果表明，对同时患有糖尿病的高血压患者采取个性化管理策略非常重要，同时也要考虑到性别特异性因素。有必要开展进一步研究，以阐明导致这些差异的潜在机制，并优化临床结果。
{"title":"Glucose variations in hypertensive patients with diabetes: A retrospective study","authors":"Kalash Dwivedi, Botirova Nigina Akram qizi, Muhammed Sinan Cheelatta","doi":"10.30574/wjbphs.2024.19.1.0397","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0397","url":null,"abstract":"Background: Hypertension (HTN) and diabetes mellitus (DM) are prevalent chronic conditions associated with significant morbidity and mortality not only in the Uzbekistan but in the whole globe . Understanding their conjoined impact on blood sugar levels, particularly about gender-specific differences, is crucial for optimizing patient management strategies. Aim: This study aims to investigate the effect of HTN on blood sugar levels in patients with and without DM, focusing on gender-specific variations. Method: A sample of 160 patients from the Tashkent Polyclinic was categorized based on Hypertension and diabetes status. Blood sugar levels were measured using a glucometer, and statistical analyses, including t-tests, were conducted to compare blood sugar levels between groups with the help of excel . Result: Significant variations in blood sugar levels were noted between patients with both HTN and DM and those with only HTN. Gender-specific differences or variance were noted, with females exhibiting higher blood sugar levels than males, particularly in the presence of both conditions HTN and DM. Conclusion: The findings give the importance of personalized management strategies for hypertensive patients with coexisting DM, also considering gender-specific factors. Further research is warranted to elucidate the underlying mechanisms driving these differences and optimize clinical outcomes.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"3 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/wjbphs.2024.19.1.0433
Chidinma Adanna OKAFOR, Ngozika Maria UKWUEZE
Mitigating Protein Energy Malnutrition (PEM) is paramount to cohort the infant mortality rate caused by inadequate nutrition. This study examines the effect of enriching maize-based starch gruel "Akamu" with Bambara groundnut flour. Yellow maize was steeped for 72 hours, with the steep water changed every 24 hours. Then, wet milled, its starch separated with a cheesecloth, oven-dried and milled to produce akamu flour. Bambara groundnut was steeped, boiled, dried and milled into flour and used to enrich (10%, 20% and 30%) the akamu. The steep water was evaluated for microbial analysis, while the sample blends were examined for proximate and sensory attributes. The microbes of steep water decreased in coliform count and pH as fermentation progressed. However, Lactobacillus spp and fungi increased from 0.93x103 and 3.63x103 to 8.42x103 and 6.62x103cfu/mL, respectively. Crude protein increased significantly from 8.64 % to 15.54 %, while carbohydrates reduced to 60.20 %. The 100% maize (control) akamu showed the highest acceptability of 6.58, while 30% Bambara groundnut was the least (3.38). Hence, this study helped to establish the nutritional improvement of akamu, a cereal starch gruel with Bambara groundnut aimed at addressing malnutrition.
{"title":"Protein-enriched Akamu: Nutritional sensory and microbial quality evaluation","authors":"Chidinma Adanna OKAFOR, Ngozika Maria UKWUEZE","doi":"10.30574/wjbphs.2024.19.1.0433","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0433","url":null,"abstract":"Mitigating Protein Energy Malnutrition (PEM) is paramount to cohort the infant mortality rate caused by inadequate nutrition. This study examines the effect of enriching maize-based starch gruel \"Akamu\" with Bambara groundnut flour. Yellow maize was steeped for 72 hours, with the steep water changed every 24 hours. Then, wet milled, its starch separated with a cheesecloth, oven-dried and milled to produce akamu flour. Bambara groundnut was steeped, boiled, dried and milled into flour and used to enrich (10%, 20% and 30%) the akamu. The steep water was evaluated for microbial analysis, while the sample blends were examined for proximate and sensory attributes. The microbes of steep water decreased in coliform count and pH as fermentation progressed. However, Lactobacillus spp and fungi increased from 0.93x103 and 3.63x103 to 8.42x103 and 6.62x103cfu/mL, respectively. Crude protein increased significantly from 8.64 % to 15.54 %, while carbohydrates reduced to 60.20 %. The 100% maize (control) akamu showed the highest acceptability of 6.58, while 30% Bambara groundnut was the least (3.38). Hence, this study helped to establish the nutritional improvement of akamu, a cereal starch gruel with Bambara groundnut aimed at addressing malnutrition.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/wjbphs.2024.19.1.0431
Bishan Sarkar, Bidisha Ghosh, Payel Choudury
Background: TARO (Colocasia esculenta) an herbal plant and used to treat type 2 diabetes in clinical practice, but the potential evidence needs to be provided. Materials and Methods: plant material is collected and extraction completed. Then perform Phytochemical screening. Type 2 diabetic model rats were induced by feeding high fat diet (HFD) . The model rats were given for 4 weeks. Then treaded with herbal medicine Results: After phytochemical study find out lots of active compound. Flavonoids and terpinoids are responsible for anti-diabetic activity. Extract significantly decreased fasting blood glucose at 750 mg/kg. Conclusion: The results display that extract performs anti-diabetic functions in type 2 diabetic rats induced by feeding HFD.
{"title":"Research work on an inevitable component to treat type 2 diabetes from the margin of Colocasia esculenta","authors":"Bishan Sarkar, Bidisha Ghosh, Payel Choudury","doi":"10.30574/wjbphs.2024.19.1.0431","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0431","url":null,"abstract":"Background: TARO (Colocasia esculenta) an herbal plant and used to treat type 2 diabetes in clinical practice, but the potential evidence needs to be provided. Materials and Methods: plant material is collected and extraction completed. Then perform Phytochemical screening. Type 2 diabetic model rats were induced by feeding high fat diet (HFD) . The model rats were given for 4 weeks. Then treaded with herbal medicine Results: After phytochemical study find out lots of active compound. Flavonoids and terpinoids are responsible for anti-diabetic activity. Extract significantly decreased fasting blood glucose at 750 mg/kg. Conclusion: The results display that extract performs anti-diabetic functions in type 2 diabetic rats induced by feeding HFD.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"1 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Understanding the relationship between exercise duration and sleep quantity among undergraduate students is essential for promoting their overall health and well-being. This study investigates this association through a cross-sectional survey of 51 students aged 18-24 at the University of Washington. The results indicate an average daily exercise duration of 32 minutes and a mean sleep duration of 7.0 hours. Analysis reveals that students with higher exercise durations exhibit a 14% reduced odds of achieving high sleep quantity compared to those with lower exercise durations. Notably, caffeine consumption serves as an effect modifier in this relationship. These findings suggest that increased exercise does not necessarily correlate with increased sleep in this population, emphasizing the need for a nuanced understanding of the factors influencing sleep among college students. Addressing these variables can inform the development of targeted interventions to enhance student health and academic performance.
{"title":"Move more, sleep more? Examining the impact of exercise duration on sleep quantity among undergraduate students at the University of Washington","authors":"Raahul Narayanan, Esther Carpenter, Leslie Jacobo, Binqi Li, Tyler Reynolds, Jack Evers","doi":"10.30574/wjbphs.2024.19.1.0399","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0399","url":null,"abstract":"Understanding the relationship between exercise duration and sleep quantity among undergraduate students is essential for promoting their overall health and well-being. This study investigates this association through a cross-sectional survey of 51 students aged 18-24 at the University of Washington. The results indicate an average daily exercise duration of 32 minutes and a mean sleep duration of 7.0 hours. Analysis reveals that students with higher exercise durations exhibit a 14% reduced odds of achieving high sleep quantity compared to those with lower exercise durations. Notably, caffeine consumption serves as an effect modifier in this relationship. These findings suggest that increased exercise does not necessarily correlate with increased sleep in this population, emphasizing the need for a nuanced understanding of the factors influencing sleep among college students. Addressing these variables can inform the development of targeted interventions to enhance student health and academic performance.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"9 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-30DOI: 10.30574/wjbphs.2024.19.1.0420
T. Aswini, K. Dhanusha, K. Priya, R. Shalini, S. Sumithra, W. Helen
Herbal sunscreen is a lotion, spray, or other topical treatment that uses herbs to help protect skin from UV radiation, limit sunburn and other skin damage, and lower the risk of skin cancer. It is also frequently referred to as herbal sunblock or herbal suntan lotion. Herbal sunscreens are a vital component of modern skincare regimens since they offer several benefits that tackle both health and environmental concerns. By obstructing UV rays, sunscreen composition seeks to improve protection against them. Herbal sunscreens have grown in popularity as an appealing substitute for traditional sun protection treatments as a result of the growing consumer demand for natural and environmentally friendly skincare products. Because of their antioxidant qualities and capacity to absorb UVA rays, flavonoids, phenolic compounds, and herbal oils are crucial for UV protection. Because these sunscreens are composed of minerals and plant-based ingredients, they provide effective protection against UV (ultraviolet) rays from the sun. Herbal sunscreens have attracted a lot of attention as natural substitutes for conventional sunscreens because they offer protection against harmful ultraviolet (UV) radiation while minimizing potential adverse effects linked to synthetic ingredients. An effective and sustainable alternative to traditional sunscreens are herbal sunscreens.
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