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Manual Acupuncture Effect on Vertigo and Tinnitus in Patient with Labyrinthitis: A Case Report 手针治疗迷路炎眩晕耳鸣1例
Pub Date : 2021-06-28 DOI: 10.19184/ams.v7i2.23803
Cindy Notonegoro, C. Simadibrata
Labyrinthitis is an inflammatory disease of the inner ear perilymphatic cavity and the most common cause of prolonged spontaneous vertigo.  Other symptoms are tinnitus and sensorineural hearing loss.  Acupuncture is one of the non-pharmacological therapeutic modalities to improve symptoms of labyrinthitis. A 54-year-old woman complained of vertigo that is preceded by tinnitus in both ears since the last 6 months.  She was diagnosed with labyrinthitis.  Had taken amoxicillin and decadryl for 5 days, betaserc and dimenhydrinate when she felt dizzy, and amlodipine as a routine drug for her hypertension.  Physical examination showed vital signs within normal limits, grade 2 obesity, positive Romberg test, and THI score 18.  Manual acupuncture was performed at acupoints GV20, GB20, TE17, TE21, SI19, GB2, GB8, TE5, LI4, KI3, PC6 and LR3 with 20 minutes retention.  After the first therapy, vertigo complaints disappeared and after 12 treatments (twice a week), frequency and intensity of tinnitus became less, with THI score of 6. Therefore, acupuncture can relieve vertigo and improve tinnitus which can be seen by a decrease of THI score. Keywords: acupuncture, labyrinthitis, tinnitus, vertigo
迷路炎是一种内耳淋巴管周围腔的炎症性疾病,是引起长时间自发性眩晕的最常见原因。其他症状有耳鸣和感音神经性听力损失。针刺是改善迷路炎症状的非药物治疗方式之一。一名54岁女性,自过去6个月以来,主诉双耳耳鸣伴眩晕。她被诊断出患有迷路炎。曾服用阿莫西林、地塞米松5天,头晕时服用倍他塞克、苯海明,高血压常规用药氨氯地平。体格检查生命体征正常,2级肥胖,Romberg试验阳性,THI评分18分。针刺穴位GV20、GB20、TE17、TE21、SI19、GB2、GB8、TE5、LI4、KI3、PC6、LR3,留置20分钟。第一次治疗后眩晕症状消失,12次治疗(每周2次)后耳鸣频率和强度减少,THI评分为6分。因此,针灸可以缓解眩晕,改善耳鸣,这可以从THI评分的降低中看出。关键词:针灸,迷路炎,耳鸣,眩晕
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引用次数: 0
Formulation of Gel from Corn Silk Extract (Stigma maydis) and Burns Healing Activity 玉米丝提取物凝胶的配方及烧伤愈合活性
Pub Date : 2021-06-28 DOI: 10.19184/ams.v7i2.20287
N. Putri, N. Nessa, Yoga Ramadhana
Corn silk (Stigma maydis) contains compounds that play a role in wound healing, such as flavonoids, saponins, tannins. This study aims to formulate a gel from corn hair extract and see its activity in healing burns. The test group was divided into four groups: group I (hot metal induction), group II (without extract ), group III (corn hair extract concentration 5%), and group IV (comparison B®), which metal induction. The parameters observed were % wound healing, epithelialization time, and histopathology. The results of the study on the average% of burns healing rate 7, 14 and 21 days, namely group I (27,92%; 62,42%; 100%), group II (35,39%; 60,16%; 100%), group III (44,05%; 63,69%; 100%) and group IV (32,81%; 66,48%; 100%). The mean time of tissue peeling epithelialization groups I, II, and III was on day 16, and group IV was on day 17. For the histopathological results, the mean score of collagen fibers, fibroblast cells, and epithelialization was respectively group I (2,2; 2,7; 2), group II (2,8; 2,9; 2), group III (3,3; 2,9; 2,7), and Group IV (3,9; 3; 3). The results of the two-way ANOVA statistical test on % burn healing (p> 0.05) and one-way ANOVA at the time of epithelialization (p> 0.05) and the histopathological score (p <0.05) showed that group III (the corn hair extract 5 %) could influence the process of healing burns. Keywords: Burns, Corn Silk Extract (Stigma maydis), % Burn Healing, Epithelialization Time, Histopathology
玉米丝(柱头maydis)含有对伤口愈合起作用的化合物,如类黄酮、皂苷、单宁。本研究旨在从玉米毛提取物中制备凝胶,并观察其在烧伤愈合中的活性。试验组分为4组:ⅰ组(热金属诱导)、ⅱ组(不加提取物)、ⅲ组(玉米毛提取物浓度5%)、ⅳ组(对照B®),均为热金属诱导。观察的参数包括伤口愈合率、上皮化时间和组织病理学。研究结果显示,第7、14、21天烧伤愈合率平均%,即ⅰ组(27.92%;62年,42%;100%), II组(35.39%;60岁的16%;100%), III组(44.05%;63年,69%;100%)和IV组(32.81%);66年,48%;100%)。ⅰ、ⅱ、ⅲ组组织剥离上皮化的平均时间为第16天,ⅳ组为第17天。组织病理学结果:ⅰ组胶原纤维、成纤维细胞、上皮化平均评分分别为(2,2;2、7;2)、II组(2,8;2、9;2), III组(3,3;2、9;2,7)和IV组(3,9;3;3).烧伤愈合百分比的双因素方差分析(p> 0.05)和上皮化时的单因素方差分析(p> 0.05)及组织病理学评分(p <0.05)结果显示,ⅲ组(5%玉米毛提取物)对烧伤愈合过程有影响。关键词:烧伤,玉米丝提取物,烧伤愈合率,上皮化时间,组织病理学
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引用次数: 0
Severe Deficit in Energy and Protein Intake Correlates wih Stunting among Children Aged 12-24 Months in Plerean Sumberjambe Jember 能量和蛋白质摄入严重不足与12-24月龄儿童发育迟缓相关
Pub Date : 2021-06-28 DOI: 10.19184/ams.v7i2.24828
N. Nurhasanah, D. Rachmawati, I. Sutejo
The current nutritional problems are still the world's attention, especially in developing countries, including Indonesia. The Global Nutrition Report shows that Indonesia is a country with three main nutritional problems: wasting, overweight, and stunting (under five) in infants. Stunting has short-term and long-term effects associated with growth and developmental disorders. This study wants to determine the correlation between energy and protein intake of children aged 12-24 months in Plerean, Sumberjambe, Jember. This is an observational research with cross sectional study design. The population of this study were all children aged 12-24 months in Plerean Village, Sumberjambe, Jember. A total of 48 parents/respondents were interviewed about the consumption history of the on the previous day. This is done to determine the energy and protein intake consumed by the research subjects. Measurement of energy and protein intake using 24-hours food recall method and stunting was obtained from secondary data obtained from Puskesmas Sumberjambe. This research used purposive sampling method. The data obtained is then converted into calorie units and processed using a statistical program. The results showed showed 28 subjects were male. Most parents of research subjects earn less than the Minimum Wage District (UMK). A total of 68.75% of subjects had severe deficit in energy intake. A total of 52.08% of subjects had a severe deficit protein. Using Spearman correlation test the correlation of energy intake with the incidence of stunting obtained p value = 0.000 with correlation coefficient -0.589. Then, the relationship of protein intake with the incidence of stunting obtained p = 0.001 with a correlation coefficient of -0.446. So it can be concluded that severe deficit in energy and protein intake correlates with stunting in the study subjects. Keywords: 24-hours food recall, Energy, Protein, Stunting  
目前的营养问题仍然是全世界关注的问题,特别是在包括印度尼西亚在内的发展中国家。《全球营养报告》显示,印度尼西亚是一个存在三大营养问题的国家:婴儿消瘦、超重和发育迟缓(五岁以下)。发育迟缓具有与生长和发育障碍相关的短期和长期影响。这项研究想要确定在Plerean, Sumberjambe, Jember的12-24个月大的儿童能量和蛋白质摄入量之间的关系。这是一项采用横断面研究设计的观察性研究。本研究的人群均为12-24个月大的儿童,他们来自Jember的Sumberjambe的Plerean村。共采访了48位家长/受访者,询问他们前一天的消费历史。这样做是为了确定研究对象消耗的能量和蛋白质摄入量。采用24小时食物回忆法测定能量和蛋白质摄入量,发育不良来自于Puskesmas Sumberjambe的二次数据。本研究采用目的抽样方法。然后将获得的数据转换成卡路里单位,并使用统计程序进行处理。结果显示,28名受试者为男性。大多数研究对象的父母的收入低于最低工资区(UMK)。68.75%的受试者存在严重的能量摄入不足。52.08%的受试者存在严重的蛋白质缺陷。采用Spearman相关检验,能量摄入与发育迟缓发生率的相关性得到p值= 0.000,相关系数为-0.589。则蛋白质摄入量与发育迟缓发生率的关系为p = 0.001,相关系数为-0.446。因此,可以得出结论,在研究对象中,能量和蛋白质摄入严重不足与发育迟缓有关。关键词:24小时食品召回,能量,蛋白质,发育不良
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引用次数: 3
Analysis of Factors Affecting the Contamination of Entamoeba sp. cyst and Soil-Transmitted Helminths egg on Dug Well Water 挖掘井水内阿米巴虫囊和土传蠕虫卵污染影响因素分析
Pub Date : 2021-06-28 DOI: 10.19184/ams.v7i2.22233
Iza Billa Fahmi, E. Sulistyaningsih, Dion Darmawan
Dug well water is often polluted by fecal waste containment such as septic tank and pit latrine system due to its distance. The common pathogenic parasites found in fecal waste containment are E. histolytica and Soil-Transmitted Helminths (STH). The port de entry of both parasites is ingestion of contaminated food or water by fecal materials. This study was aimed to analyze factors affecting the existence of Entamoeba sp. cyst and STH egg on dug well water in Bungatan Village, Situbondo. This observational analytic study used cross-sectional approach, carried out 30 respondents in Bungatan Village, Situbondo. Entamoeba sp. cyst and STH egg were examined using sedimentation method, the distance of fecal waste containment to dug well measured by measuring tape. The characteristic of fecal waste containment and dug well was observed using questionnaires. The results showed 100% fecal containment used pit latrine system, 100% had an incomplete well standard, 66,7% had unstandardized distance with fecal waste containment. Entamoeba sp. cyst and STH egg were not found on all water samples. The soil condition near the dug well (acidity, temperature, moisture, and sunlight intensity) and physical condition (temperature) of dug well water were inappropriate to the development of Entamoeba sp. cyst and STH egg. The dug well's component and its distance to fecal containment did not affect Entamoeba sp. cyst and STH egg existence in all dug well water. The physical soil condition near the dug well and the temperature of dug well water were inappropriate to the development of both parasites. Keywords: Entamoeba sp., Soil Transmitted Helminths, Dug Well, Fecal Waste Containment
由于距离较远,挖井水往往受到化粪池、坑厕系统等粪便废物容器的污染。在粪便容器中发现的常见致病寄生虫是溶组织肠杆菌和土传蠕虫。这两种寄生虫的入境口岸是通过粪便物质摄入受污染的食物或水。本研究旨在分析影响司图本多邦邦邦邦邦邦邦邦邦村挖井水中内阿米巴虫囊和卵存在的因素。本观察性分析研究采用横断面方法,对斯图邦多邦加坦村的30名受访者进行了调查。采用沉降法检测内阿米巴虫囊和卵,用卷尺测量粪便容器到挖井的距离。采用问卷调查的方式对粪污围堵及挖井特点进行了观察。结果表明:100%采用坑式公厕,100%井口标准不全,66.7%与粪污容器距离不规范。所有水样均未检出内阿米巴原虫囊肿及卵。挖井附近的土壤条件(酸度、温度、湿度、光照强度)和挖井水的物理条件(温度)都不适合内阿米巴虫囊和卵的发育。挖井的组成及其与粪便容器的距离对所有挖井水中内阿米巴虫囊和卵的存在没有影响。井水温度和井水附近的土壤物理条件都不适宜这两种寄生虫的生长发育。关键词:内阿米巴虫;土壤传播蠕虫;挖井
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引用次数: 0
Antibacterial and Antifungal Activity of Galam (Melaleuca cajuputi subsp. Cumingiana (Turcz.) Barlow) Extract against E. coli bacteria and C. albicans fungi 百层木的抑菌抑菌活性。Cumingiana (Turcz)。巴洛)提取物对大肠杆菌和白色念珠菌
Pub Date : 2021-06-28 DOI: 10.19184/ams.v7i2.23467
Isnaini Isnaini, A. Biworo, H. Khatimah, Khusnan Mustofa Gufron, Shafa Rahmani Puteri
Galam (Melaleuca cajuputi subsp. Cumingiana (Turcz.) Barlow) is a peat swamp forest plant. This plant is used to treat respiratory diseases, colitis, sore throat, itchy skin, diarrhea, and dizziness. This study aimed to analyze the antibacterial and antifungal activity of the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow flowers and fruit against Escherichia coli and Candida albicans bacteria. This research is a pretest-posttest research with control group design and consists of 3 stages of research. The first stage is the phytochemical screening test, the second stage determines the minimum inhibitory concentration (MIC) and the third determines the minimum bactericidal concentration (MBC). The results showed that the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow flowers and fruit contained terpenoids, flavonoids, phenols, saponins, quinones, steroids, tannins, while alkaloid compounds only found in the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow fruit. The MIC and MBC values ​​of M. cajuputi subsp. Cumingiana (Turcz.) Barlow flower methanol extract against E. coli were 1.67 and 2.083 mg/mL, respectively, while the MIC and MBC values ​​of the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow flower against C. albicans were 3.125 and 25 mg/mL. The MIC and MBC values ​​of the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow fruit against E. coli have same value  were 3.334 mg/mL, while the MIC and MBC values ​​of the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow fruit against C. albicans were 3.125 and 12.5 mg/mL, respectively. Keywords: Galam  antibacterial, antifungal, Escherichia coli, Candida albicans
千层木耳(千层木耳)Cumingiana (Turcz)。Barlow)是一种泥炭沼泽森林植物。这种植物用于治疗呼吸系统疾病,结肠炎,喉咙痛,皮肤瘙痒,腹泻和头晕。本研究旨在分析枣果霉甲醇提取物的抑菌和抗真菌活性。Cumingiana (Turcz)。巴罗花和果实抗大肠杆菌和白色念珠菌。本研究为前测后测研究,采用对照组设计,共分为3个研究阶段。第一阶段为植物化学筛选试验,第二阶段确定最低抑菌浓度(MIC),第三阶段确定最低杀菌浓度(MBC)。结果表明:枣果子的甲醇提取物;Cumingiana (Turcz)。巴罗花和果实中含有萜类、黄酮类、酚类、皂苷类、醌类、甾体、单宁等,而生物碱类化合物仅在巴罗花的甲醇提取物中发现。Cumingiana (Turcz)。巴洛水果。研究了黑枣子菌的MIC和MBC值。Cumingiana (Turcz)。巴罗花甲醇提取物对大肠杆菌的抑菌效果分别为1.67和2.083 mg/mL;Cumingiana (Turcz)。巴罗花对白色念珠菌的抑制作用分别为3.125和25 mg/mL。测定了枳实甲醇提取物的MIC值和MBC值。Cumingiana (Turcz)。巴罗果对大肠杆菌的抑菌活性均为3.334 mg/mL,巴罗果甲醇提取物对大肠杆菌的抑菌活性均为3.334 mg/mL。Cumingiana (Turcz)。巴罗果对白色念珠菌的抑制作用分别为3.125和12.5 mg/mL。关键词:Galam抗菌,抗真菌,大肠杆菌,白色念珠菌
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引用次数: 3
Prevalence of Stunting According to WHO Growth Standards and Indonesian Growth Reference Charts: A Descriptive Study from Blega Sub-District 根据世界卫生组织生长标准和印度尼西亚生长参考图的发育迟缓患病率:来自Blega街道的描述性研究
Pub Date : 2021-06-28 DOI: 10.19184/ams.v7i2.23868
N. Hilmy, Maitsa' Fatharani
Stunting is one of the remaining health issues in Indonesia and its prevalence was still high in the last decades. There are two types of growth charts that can be used in recording the child's growth: growth standards and growth references. In recent times, the selection of the suitable growth charts has become a subject of discussion in many countries. The objective of this study is to describe the prevalence of stunting according to World Health Organization Child Growth Standards (WHOCGS) and Indonesian National Growth Reference Charts (INGRC) of children under five from the Blega sub-district. The secondary data from 2884 children were collected recapitulation of the 'Bulan Timbang' program in February 2020. Z-score of length/height-for-age was plotted according to WHOCGS and INGRC. The result showed that the prevalence of stunting were lower for the INGRC than WHOCGS (5.83% and 11.17%, with p-value <0.001). There was an advantage and disadvantage when using both two growth charts. Further research is still needed to support the result of this study. Keywords:  Stunting, World Health Organization Child Growth Standards, Indonesian National Growth Reference Charts
发育迟缓是印度尼西亚仍然存在的健康问题之一,在过去几十年中,其患病率仍然很高。有两种类型的生长图表可用于记录儿童的生长:生长标准和生长参考。近年来,选择合适的增长图表已成为许多国家讨论的主题。这项研究的目的是根据世界卫生组织儿童生长标准和印度尼西亚国家生长参考图描述布雷加街道五岁以下儿童发育迟缓的流行情况。来自2884名儿童的次要数据是在2020年2月“Bulan Timbang”计划的重述中收集的。根据WHOCGS和inggrc绘制长度/身高年龄比值z分数。结果显示,INGRC组发育迟缓发生率低于WHOCGS组(5.83%和11.17%,p值<0.001)。同时使用这两种增长图表各有利弊。本研究结果还需要进一步的研究来支持。关键词:发育迟缓,世界卫生组织儿童生长标准,印度尼西亚国家生长参考图
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引用次数: 1
DNA Quality and Quantity on Blood Spot Post Soil and Ultraviolet-C Exposure 血斑后土壤和uv - c暴露的DNA质量和数量
Pub Date : 2020-10-12 DOI: 10.19184/AMS.V6I3.19937
M. A. Jauhani, Sheilla Rachmania
Bercak darah dapat ditemukan di tempat kejadian perkara (TKP) pada banyak kasus tindak kekerasan. Asam deoksiribonukleat (DNA) pada darah dapat digunakan sebagai data primer untuk proses identifikasi akan tetapi bercak darah di TKP berisiko rusak akibat pajanan tanah dan ultraviolet. Tujuan utama dari penelitian ini adalah untuk mempelajari efek kombinasi dari pajanan sinar ultraviolet-C dan tanah terhadap kualitas dan kuantitas DNA pada bercak darah. Sebanyak 20 gelas berisi 200 gram tanah ditetesi 900µl darah dan diberikan pajanan sinar ultraviolet-C dalam tiga kelompok berdasarkan durasi pajanan yakni satu hari, tiga hari, dan lima hari. Satu kelompok digunakan sebagai kontrol. Ekstraksi DNA dilakukan menggunakan DNAZol dilanjutkan dengan pengukuran spektrofotometri untuk mengetahui kualitas dan kuantitas DNA. Peningkatan konsentrasi DNA dapat diamati yaitu 681,1 pada hari pertama menjadi 1274,7 pada hari ketiga dan mulai menurun menjadi 1090,6 pada hari kelima, sedangkan kemurnian DNA terus menurun secara konstan seiring dengan meningkatnya durasi pajanan. Penelitian ini menunjukkan bahwa pajanan sinar ultraviolet-C dan tanah menyebabkan degradasi molekul DNA menjadi fragmen-fragmen molekul yang lebih kecil sehingga terjadi peningkatan kuantitas DNA yang disertai penurunan kualitas DNA. Penurunan kualitas DNA dapat mempersulit proses identifikasi sehingga isolasi DNA sampel pada tanah terbuka yang terpajan matahari harus dilakukan sesegera mungkin.   Kata Kunci: DNA, darah, tanah, ultraviolet C, patologi forensik
在许多暴力案件中,可以在犯罪现场发现血迹。血液中的脱氧核糖核酸(DNA)可以作为鉴定过程的主要数据,但犯罪现场的血迹有被土壤和紫外线破坏的危险。这项研究的主要目的是研究紫外线和土壤对流DNA质量和数量的结合效果。多达20杯含有200克土地ditetesi 900µl血和射线曝光ultraviolet-C分成三组根据曝光时长就是一天,三天五天。一组用作控制。DNA提取是用DNAZol进行的,然后用光谱测量来确定DNA的质量和数量。可以观察到第一天681.1的DNA浓度增加到第三天的1274.7,第5天开始下降到1090.6,而DNA的纯度随着疼痛持续时间的增加而持续下降。这项研究表明,紫外线和土壤物质导致DNA分子的分子分解成更小的分子碎片,从而增加了DNA的数量,并伴有DNA质量的下降。DNA质量的下降可能会使识别过程变得困难,以便尽快从暴露在阳光下的裸露土壤中分离DNA样本。关键词:DNA,血液,土壤,紫外线,法医病理学家
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引用次数: 0
The Effect of Zumba Exercise to Women's Waist Hip Ratio 尊巴运动对女性腰臀比的影响
Pub Date : 2020-05-29 DOI: 10.19184/AMS.V6I2.17449
Laksmi Indreswari, Yunita Anggraeni, Rena Normasari
Abdominal obesity is a global public health problem. The high prevalence of abdominal obesity triggers an increase in morbidity and mortality in chronic diseases such as diabetes mellitus, cardiovascular, and cancer. One of the causes of the high prevalence of abdominal obesity is the lack of physical activity. Prevention efforts are needed through the identification of risk factors such as measurement of waist hip ratios. The respondents of this study were divided into two groups: 28 respondents who did zumba exercise for four weeks and 28 control respondents. The statistical test performed was a paired t-test comparison test. The results of this study indicate the value of t-count > t-table value (7.184 > 2.052) and the significance of 0.000 < 0.05. These results indicate that there is a decrease in the waist hip ratio after doing zumba exercise for four weeks.
腹部肥胖是一个全球性的公共卫生问题。腹部肥胖的高流行率导致慢性疾病如糖尿病、心血管疾病和癌症的发病率和死亡率增加。腹部肥胖高发的原因之一是缺乏体育锻炼。需要通过识别危险因素(如测量腰臀比)来预防。本研究的被调查者分为两组:28名做尊巴舞四周的被调查者和28名对照组。统计检验采用配对t检验比较检验。本研究结果表明,t-count值> t-table值(7.184 > 2.052),显著性为0.000 < 0.05。这些结果表明,在进行尊巴运动四周后,腰臀比有所下降。
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引用次数: 1
The Effectiveness of Vitamin C Addition to Blood Glucose Levels of Hyperglycemic Mice with Glimepiride Treatment 添加维生素C对格列美脲治疗高血糖小鼠血糖水平的影响
Pub Date : 2020-05-20 DOI: 10.19184/AMS.V6I3.9994
Indi Kamilia Fitri, Cholis Abrori, D. K. Dharmawan
In people with diabetes mellitus (DM) there is a decrease in basal vitamin C levels which is thought to be a result of oxidative stress in the condition of hyperglycemia that it needs to increase vitamin C as an antioxidant. Hyperglycemia in DM needs to be lowered by pharmacological therapy, named glimepirid so the purpose of this study is to determine the effectiveness of vitamin C addition to the reduction of KGD hyperglycemic mice with glimepirid treatment. This study is true experimental with a sample of 25 mice 20-30 grams and divided into five groups, first the control group (K0); STZ  induction group (K1); STZ induction group with glimepirid treatment (K2); STZ induction group with the treatment of vitamin C (K3); STZ induction group by treatment of a combination of glimepirid and vitamin C (K4). STZ is injected intraperitonially 150 mg / kgBB. All groups were measured for KGD 1 after induction of STZ and KGD 2 after treatment for fourteen days. The results of the STZ induction group with the treatment of a combination of glimepirid and vitamin C (K4) experienced a smaller and not significant decrease in BSL in the STZ induction group with a single glimepirid (K2) treatment. These results are thought to have an influence from interactions between drugs that cause one drug to not work optimally. The conclusion of this study is that administration of glimepirid, vitamin C, or both can reduce blood glucose levels in hyperglycemic mice with the greatest decrease occurring in the glimepirid group.
在糖尿病患者中,基础维生素C水平下降,这被认为是高血糖状态下氧化应激的结果,需要增加维生素C作为抗氧化剂。糖尿病的高血糖需要通过药物治疗来降低,因此本研究的目的是确定维生素C在格列美吡嗪治疗下降低KGD高血糖小鼠的有效性。本研究为真实验,以25只20-30克的小鼠为样本,分为五组,首先是对照组(K0);STZ诱导组(K1);格列美脲治疗STZ诱导组(K2);STZ诱导组用维生素C (K3)处理;格列美脲联合维生素C (K4)诱导STZ组。STZ腹腔注射150 mg / kgBB。各组在STZ诱导后测定KGD 1和处理后14d测定KGD 2。glimepirid与维生素C (K4)联合处理的STZ诱导组的BSL下降幅度小于单一glimepirid (K2)处理的STZ诱导组,且不显著。这些结果被认为是由于药物之间的相互作用导致一种药物不能达到最佳效果。本研究的结论是,给药格列美脲、维生素C或两者都可以降低高血糖小鼠的血糖水平,其中格列美脲组的下降幅度最大。
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引用次数: 1
Evaluation of CD4 Number In HIV / AIDS Patients Who Are Running The Antiretrovial Treatment Program 抗逆转录病毒治疗方案对HIV / AIDS患者CD4细胞数量的影响
Pub Date : 2020-02-17 DOI: 10.19184/AMS.V6I2.16790
Thatit Nurmawati, Yeni Kartika Sari, Aprilia Putri Hidayat
HIV is a health problem for Indonesia and the world. Enforcement of diagnoses and control efforts  continue to be made to reduce the number of HIV / AIDS cases. ARVs are becoming efforts to cure HIV by increasing CD4 cell counts. CD4 cell count is a determinant of ARV therapy. The purpose of this study was to evaluate CD4 cell counts in people with HIV / AIDS who were implementing ARV programs. The study design was observational using secondary data in the form of medical record records. The study population was HIV sufferers who registered to run an HIV / AIDS antiretrovial treatment program at the Cendana Poly Ngudi Waluyo Regional Hospital in Blitar in June 2017. Samples in the study were 30 people according to inclusion and exclusion criteria with a sampling technique using a purposive sampling method. Research instruments using questionnaires. Data analysis uses descriptive method. The results showed that this CD4 cell count had a CD4 cell count of 200 cells / mm 3 by 10%, 200-499 by 90% in patients who were on ARV programs. The patient's condition and obata resistance result in a CD4 cell count not exceeding 500 mm / cell. Key words: amount CD4, ARV , patient HIV
艾滋病毒是印度尼西亚和全世界的一个健康问题。继续执行诊断和控制工作,以减少艾滋病毒/艾滋病病例的数量。抗逆转录病毒药物正成为通过增加CD4细胞计数来治愈艾滋病毒的努力。CD4细胞计数是抗逆转录病毒治疗的决定因素。本研究的目的是评估正在实施抗逆转录病毒治疗方案的艾滋病毒/艾滋病患者的CD4细胞计数。本研究采用观察性设计,采用医疗记录形式的辅助资料。研究人群是艾滋病毒患者,他们于2017年6月在布利塔的Cendana Poly Ngudi Waluyo地区医院注册了艾滋病毒/艾滋病抗逆转录病毒治疗项目。本研究采用有目的的抽样方法,按纳入和排除标准取样30人。使用问卷调查的研究工具。数据分析采用描述性方法。结果表明,在接受抗逆转录病毒治疗的患者中,CD4细胞计数为200个细胞/ mm 3的比例为10%,200-499的比例为90%。患者的病情和抗氧性导致CD4细胞计数不超过500mm /细胞。关键词:CD4, ARV, HIV患者
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Journal of Agromedicine and Medical Sciences
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