Stage V Chronic Kidney Disease (CKD) is one of the most common medical case in the world. Stage V CKD defined as a condition where the renal function decrease progressively, marked by the GFR <15/ml/minute/1,73 m2, with or without kidney damage history for three months. Patients diagnosed with Stage V CKD often needs kidney replacement therapy, one of which is hemodialysis. The cost needed for hemodialysis was considered as too expensive, forcing lots of medical staff in most countries using the method known as re-use hemodialyzer. Re-use hemodialyzer is a term for using the same hemodialyzer (or hemodialysis machine) for the same patient but on a different therapy session. The main purpose for this research is to investigate the sodium level in patients with Stage V CKD whose using new and re-use hemodialyzer in Hemodialysis Installation of RSD dr. Soebandi Jember. Analytic Observational Study is used for this research combined with Cross Sectional Study in December 2018. Total of 19 samples chosen with inclusion and exclusion criteria. Collected data is analyzed using paired t-test. The conclusion that can be obtained from this research is that there is no significant difference between sodium level in patients with Stage V CKD whose using new and re-use hemodialyzer (p=0,904). The effectivity and quality of the hemodialyzer is thought to be the main factor for this result. Keywords: Chronic Kidney Disease, sodium, re-use hemodialyzer
{"title":"Comparison of Sodium Levels in Patients with Stage V Chronic Kidney Disease Whose Using New and Re-use Hemodialyzer in Hemodialysis Installation RSD dr. Soebandi Jember","authors":"Yuli Hermansyah, Firda Novidyawati, Ayu Munawaroh Azis","doi":"10.19184/AMS.V6I1.9612","DOIUrl":"https://doi.org/10.19184/AMS.V6I1.9612","url":null,"abstract":"Stage V Chronic Kidney Disease (CKD) is one of the most common medical case in the world. Stage V CKD defined as a condition where the renal function decrease progressively, marked by the GFR <15/ml/minute/1,73 m2, with or without kidney damage history for three months. Patients diagnosed with Stage V CKD often needs kidney replacement therapy, one of which is hemodialysis. The cost needed for hemodialysis was considered as too expensive, forcing lots of medical staff in most countries using the method known as re-use hemodialyzer. Re-use hemodialyzer is a term for using the same hemodialyzer (or hemodialysis machine) for the same patient but on a different therapy session. The main purpose for this research is to investigate the sodium level in patients with Stage V CKD whose using new and re-use hemodialyzer in Hemodialysis Installation of RSD dr. Soebandi Jember. Analytic Observational Study is used for this research combined with Cross Sectional Study in December 2018. Total of 19 samples chosen with inclusion and exclusion criteria. Collected data is analyzed using paired t-test. The conclusion that can be obtained from this research is that there is no significant difference between sodium level in patients with Stage V CKD whose using new and re-use hemodialyzer (p=0,904). The effectivity and quality of the hemodialyzer is thought to be the main factor for this result. \u0000Keywords: Chronic Kidney Disease, sodium, re-use hemodialyzer","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115144498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Gentamicin usage can cause the damage of liver structure and function. The basic mechanism inducing liver damage from gentamicin is lipid peroxidation in cell membrane and the suppresion of antioxidant defence system in liver. Antioxidant in cassava leaf such as vitamin C, carotene, flavonoid, dan mineral can protect liver from drug toxicity effect. This research aimed to determine hepatoprotective effect of cassava leaf through microscopic observation of liver histopathology slide of mice induced by gentamicin. The research design was post test only control group design. Mice were divided into five groups, normal group, positive control (gentamicin 80 mg/kg b.w.); P1, P2, and P3 (gentamicin 80 mg/kg b.w. and cassava leaf extract 150 mg/kg b.w., 300 mg/kg b.w., 450 mg/kg b.w. respectively, for 14 days). The average score of liver cell damage was determined by microscopic observation of 200 liver cells undergoing parenchymal degeneration, hidrophic degeneration, and necrosis. One Way Anova analysis showed significant difference among the groups (p<0,05) and Post Hoc Tukey HSD test showed that cassava leaf extract at the dose level of 450 mg/kg b.w. resulted significant liver cell characteristic improvement in liver histophatology slide (p<0,05) compared to positive control group. It could be concluded that cassava leaf extract had protective effect on gentamicin-induced hepatotoxicity in mice. Keywords: cassava leaf extract, hepatotoxicity, gentamicin, liver histopathology
{"title":"Protective Effect of Cassava Leaf Extract on Gentamicin-Induced Hepatotoxity In Mice","authors":"R. Dewi, Rena Normasari","doi":"10.19184/ams.v5i3.13815","DOIUrl":"https://doi.org/10.19184/ams.v5i3.13815","url":null,"abstract":"Abstract \u0000Gentamicin usage can cause the damage of liver structure and function. The basic mechanism inducing liver damage from gentamicin is lipid peroxidation in cell membrane and the suppresion of antioxidant defence system in liver. Antioxidant in cassava leaf such as vitamin C, carotene, flavonoid, dan mineral can protect liver from drug toxicity effect. This research aimed to determine hepatoprotective effect of cassava leaf through microscopic observation of liver histopathology slide of mice induced by gentamicin. The research design was post test only control group design. Mice were divided into five groups, normal group, positive control (gentamicin 80 mg/kg b.w.); P1, P2, and P3 (gentamicin 80 mg/kg b.w. and cassava leaf extract 150 mg/kg b.w., 300 mg/kg b.w., 450 mg/kg b.w. respectively, for 14 days). The average score of liver cell damage was determined by microscopic observation of 200 liver cells undergoing parenchymal degeneration, hidrophic degeneration, and necrosis. One Way Anova analysis showed significant difference among the groups (p<0,05) and Post Hoc Tukey HSD test showed that cassava leaf extract at the dose level of 450 mg/kg b.w. resulted significant liver cell characteristic improvement in liver histophatology slide (p<0,05) compared to positive control group. It could be concluded that cassava leaf extract had protective effect on gentamicin-induced hepatotoxicity in mice. \u0000Keywords: cassava leaf extract, hepatotoxicity, gentamicin, liver histopathology","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115326550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mardhiyyah Nurul Hasanah, D. Rachmawati, Erfan Efendi
Abstract The first three years of age is an important period for the development of children’s languange. Early stimulation as a parent especially mother to promote children’s development needs to be done. Before doing stimulation, the mothers need sufficient knowledge about development stimulation so mothers can do stimulation properly to their children. The aim of this study is to analyze the correlation between the mother’s knowledge about language stimulation and language development of toddlers in Lengkong , Mumbulsari, Jember. An analitic observational study with cross sectional study design which the subjects were 70 mother who have toddlers at Lengkong, Mumbulsari, Jember who met inclusion and exclusion criteria. The result of spearman correlation test between mother’s knowledge about language stimulation and language development of children aged 1-3 years is p=0,000 (p<0.005) which mean there is significant correlation between the mother’s knowledge about language stimulation and language development of children aged 1-3 years in Lengkong , Mumbulsari, Jember. Keywords: knowledge, stimulation, language development.
{"title":"The correlation between Mother's Knowledge About Language Stimulation and Language Development Of Toddlers in Lengkong, Mumbulsari, Jember","authors":"Mardhiyyah Nurul Hasanah, D. Rachmawati, Erfan Efendi","doi":"10.19184/ams.v5i3.9628","DOIUrl":"https://doi.org/10.19184/ams.v5i3.9628","url":null,"abstract":"Abstract \u0000The first three years of age is an important period for the development of children’s languange. Early stimulation as a parent especially mother to promote children’s development needs to be done. Before doing stimulation, the mothers need sufficient knowledge about development stimulation so mothers can do stimulation properly to their children. The aim of this study is to analyze the correlation between the mother’s knowledge about language stimulation and language development of toddlers in Lengkong , Mumbulsari, Jember. An analitic observational study with cross sectional study design which the subjects were 70 mother who have toddlers at Lengkong, Mumbulsari, Jember who met inclusion and exclusion criteria. The result of spearman correlation test between mother’s knowledge about language stimulation and language development of children aged 1-3 years is p=0,000 (p<0.005) which mean there is significant correlation between the mother’s knowledge about language stimulation and language development of children aged 1-3 years in Lengkong , Mumbulsari, Jember. \u0000 \u0000Keywords: knowledge, stimulation, language development.","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127358909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dina Ayu Savitri, Yonas Hadisybroto, Pipiet Wulandari
One of the indirect causes of maternal death is anemia. Anemia in pregnancy is a woman with a hemoglobin level below 11 g / dl caused by iron deficiency in pregnant women so that the hemoglobin level becomes low and cannot meet the need for oxygen to perfusion to the tissues. This consumes energy in the affected muscles and buildup of lactic acid which causes fatigue and reduced muscle contraction during labor. Inadequate uterine contractions are called uterine inertia and are characterized by a prolonged phase of labor, which is weak, rarely and short duration. The purpose of this study was to determine the differences in the incidence of uterine inertia between labor and anemia released in RSD dr. Soebandi Jember. This study was analytic observational with a cross sectional research design. The study population was all pregnant women who had improved labor and were included in the medical record at RSD Dr. Soebandi Jember period January 1, 2017 - December 31, 2017. Samples from this study were mothers who had approved the delivery and fulfilled the inclusion and exclusion criteria that had been determined until the number of samples could be fulfilled. The number of samples in this study were 76 samples. The type of data used in this study is secondary data obtained by researchers from the medical records of pregnant women who have received labor. The data included in this study contain demographic data consisting of the age of pregnant women and parity, clinical data in the form of uterine inertia and laboratory data consisting of anemia status. In analyzing the data with Chi Square test (X²), a significance value of 0.011 was obtained so that it can be concluded that Ho is rejected and Ha is accepted which means that the incidence of uterine inertia between free labor and anemia is not important in RSD Dr. Soebandi Jember. Keywords: anemia, uterine inertia, pregnancy, age, parity.
产妇死亡的间接原因之一是贫血。妊娠贫血是指孕妇缺铁导致血红蛋白水平低于11g / dl，使血红蛋白水平变低，不能满足氧向组织灌注的需要。这会消耗受影响肌肉的能量和乳酸的积累，从而导致疲劳和分娩时肌肉收缩减少。子宫收缩不足被称为子宫惯性，其特征是产程延长，产程弱，很少，持续时间短。本研究的目的是确定分娩和RSD中释放的贫血之间子宫惯性发生率的差异。本研究采用横断面研究设计的分析观察法。研究人群为所有分娩改善的孕妇，并被纳入RSD Dr. Soebandi Jember(2017年1月1日至2017年12月31日)的医疗记录。本研究的样本是已批准分娩并符合纳入和排除标准的母亲，直到样本数量可以满足。本研究样本数量为76个样本。本研究使用的数据类型是研究人员从分娩孕妇的医疗记录中获得的二手数据。本研究的数据包括人口统计数据，包括孕妇的年龄和胎次，临床数据，包括子宫惯性和实验室数据，包括贫血状况。在对数据进行X²检验分析时，得到显著性值为0.011，因此可以得出Ho被拒绝，Ha被接受的结论，这意味着自由分娩与贫血之间子宫惯性的发生率在RSD中并不重要。关键词:贫血，子宫惯性，妊娠，年龄，胎次。
{"title":"The Difference Incidence of Maternal Uterine Inertia Between Labor With and Without Anemia in Hospital of dr. Soebandi Jember","authors":"Dina Ayu Savitri, Yonas Hadisybroto, Pipiet Wulandari","doi":"10.19184/ams.v5i3.9514","DOIUrl":"https://doi.org/10.19184/ams.v5i3.9514","url":null,"abstract":"One of the indirect causes of maternal death is anemia. Anemia in pregnancy is a woman with a hemoglobin level below 11 g / dl caused by iron deficiency in pregnant women so that the hemoglobin level becomes low and cannot meet the need for oxygen to perfusion to the tissues. This consumes energy in the affected muscles and buildup of lactic acid which causes fatigue and reduced muscle contraction during labor. Inadequate uterine contractions are called uterine inertia and are characterized by a prolonged phase of labor, which is weak, rarely and short duration. The purpose of this study was to determine the differences in the incidence of uterine inertia between labor and anemia released in RSD dr. Soebandi Jember. This study was analytic observational with a cross sectional research design. The study population was all pregnant women who had improved labor and were included in the medical record at RSD Dr. Soebandi Jember period January 1, 2017 - December 31, 2017. Samples from this study were mothers who had approved the delivery and fulfilled the inclusion and exclusion criteria that had been determined until the number of samples could be fulfilled. The number of samples in this study were 76 samples. The type of data used in this study is secondary data obtained by researchers from the medical records of pregnant women who have received labor. The data included in this study contain demographic data consisting of the age of pregnant women and parity, clinical data in the form of uterine inertia and laboratory data consisting of anemia status. In analyzing the data with Chi Square test (X²), a significance value of 0.011 was obtained so that it can be concluded that Ho is rejected and Ha is accepted which means that the incidence of uterine inertia between free labor and anemia is not important in RSD Dr. Soebandi Jember. \u0000Keywords: anemia, uterine inertia, pregnancy, age, parity. \u0000 ","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134446659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The use of organophosphate pesticides by farmers can cause long-term health risks, one of which is an increase in blood glucose levels. This study aims to determine whether there is a relationship between the levels of cholinesterase as an indicator of exposure to organophosphate pesticides and blood glucose of farmers in Sukorambi Village, Jember Regency. Secondary data in the form of general characteristics of the sample were obtained through interviews, while the primary data was obtained from examining the levels of cholinesterase and blood glucose levels of farmers at the Biochemical Laboratory of the Faculty of Medicine, Jember University. The research method is observational-analytic with cross-sectional study design. Based on the results of statistical analysis using the Spearman correlation test (p = 0.05), it was concluded that there was no significant relationship between the two variables (p = 0.0802).
{"title":"Correlation between Cholinesterase Levels and Blood Glucose Levels in Farmers Exposed to Organophosphate Pesticide in Desa Sukorambi Kabupaten Jember","authors":"Sofiannisa Achmadila, K. Sofiana, Y. Nurdian","doi":"10.19184/ams.v5i3.9652","DOIUrl":"https://doi.org/10.19184/ams.v5i3.9652","url":null,"abstract":"The use of organophosphate pesticides by farmers can cause long-term health risks, one of which is an increase in blood glucose levels. This study aims to determine whether there is a relationship between the levels of cholinesterase as an indicator of exposure to organophosphate pesticides and blood glucose of farmers in Sukorambi Village, Jember Regency. Secondary data in the form of general characteristics of the sample were obtained through interviews, while the primary data was obtained from examining the levels of cholinesterase and blood glucose levels of farmers at the Biochemical Laboratory of the Faculty of Medicine, Jember University. The research method is observational-analytic with cross-sectional study design. Based on the results of statistical analysis using the Spearman correlation test (p = 0.05), it was concluded that there was no significant relationship between the two variables (p = 0.0802).","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123916494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stage 5 chronic kidney disease (CKD) is a condition where the renal function decrease, marked by the GFR value < 15/ml/minute/1,73 m2 with or without kidney damage history for 3 months or more that needs kidney replacement therapy, including hemodialysis. In Indonesia, hemodialysis was chosen for 82% from all the cases that needs kidney replacement therapy. However, the cost for hemodialysis therapy is considered as too expensive and burdens The National Health Insurance, Badan Penyelenggara Jaminan Sosial (BPJS), allowing the reuse of hemodialyzer as an alternative for cost-effectiveness. Re-use hemodialyzer is a term for using the same hemodialyzer for the same patient but on different therapy session. The main purpose of this research is to investigate the difference of Potassium level in stage 5 chronic kidney disease patients whose using new and re-use hemodialyzer in RSD dr. Soebandi Jember. This research used quasi experimental design by using blood sample that will be measured for the potassium level after using new hemodialyzer and re-use hemodialyzer for the 4th time in Hemodialysis Installation of RSD dr. Soebandi Jember on December 2018. Total sample of 19 patients chosen using inclusion and exclusion criteria. Collected data were analyzed using paired t-test. The result of statistical test shows that there is no significance potassium level difference in stage 5 chronic kidney disease whose using new and re-use hemodialyzer for the 4th time (p=0,094). The effectivity of hemodialyzer that still has a good condition and hemodialysis therapy that has been done in accordance with the procedure until the 4th reuse is the main factor of this result. Keywords: CKD, potassium, re-use hemodialyzer
{"title":"The Difference of Potassium Level in Stage 5 Kidney Chronic Disease Patients Whose Using New and Re-use Hemodialyzer in RSD dr. Soebandi Jember","authors":"Yuli Hermansyah, Dinda Ayu Wanodya Supriatiningsih, Bagus Hermansyah","doi":"10.19184/ams.v5i3.9540","DOIUrl":"https://doi.org/10.19184/ams.v5i3.9540","url":null,"abstract":"Stage 5 chronic kidney disease (CKD) is a condition where the renal function decrease, marked by the GFR value < 15/ml/minute/1,73 m2 with or without kidney damage history for 3 months or more that needs kidney replacement therapy, including hemodialysis. In Indonesia, hemodialysis was chosen for 82% from all the cases that needs kidney replacement therapy. However, the cost for hemodialysis therapy is considered as too expensive and burdens The National Health Insurance, Badan Penyelenggara Jaminan Sosial (BPJS), allowing the reuse of hemodialyzer as an alternative for cost-effectiveness. Re-use hemodialyzer is a term for using the same hemodialyzer for the same patient but on different therapy session. The main purpose of this research is to investigate the difference of Potassium level in stage 5 chronic kidney disease patients whose using new and re-use hemodialyzer in RSD dr. Soebandi Jember. This research used quasi experimental design by using blood sample that will be measured for the potassium level after using new hemodialyzer and re-use hemodialyzer for the 4th time in Hemodialysis Installation of RSD dr. Soebandi Jember on December 2018. Total sample of 19 patients chosen using inclusion and exclusion criteria. Collected data were analyzed using paired t-test. The result of statistical test shows that there is no significance potassium level difference in stage 5 chronic kidney disease whose using new and re-use hemodialyzer for the 4th time (p=0,094). The effectivity of hemodialyzer that still has a good condition and hemodialysis therapy that has been done in accordance with the procedure until the 4th reuse is the main factor of this result. \u0000 \u0000Keywords: CKD, potassium, re-use hemodialyzer","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133207869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perinatal death is an indicator of the success implementing a country's health services. Perinatal death rate in Indonesia in 2012 was 26/1000 live births. In 2017 there were 225 cases of infant mortality from 34,669 births in Jember Regency. Perinatal death is influenced by maternal, infant, health services and the living environment. The environmental conditions of the residence can be affected by cigarette smoke. The aim of this study was to determine the relationship of exposure tobacco smoke in pregnant women with perinatal death in Jember Regency and to find out the main source of exposure tobacco smoke in pregnant women in Jember Regency. Type of research is analytic observation with case control study design. The sampling technique is consecutive sampling. The study sample was mothers who had a dead baby in the perinatal period (perinatal death) who resided in the Jember regency on the birth of January-December 2017. The sample size was 30 for each group. Collected data was carried out by univariate analysis and bivariate analysis using the chi-square test and fisher exact test if the chi-square test requirements were not met. Results of univariate analysis in this study showed that 89.47% of the main sources of exposure tobacco smoke originated from home and 73.68% from husbands. Results of the chi-square test between exposure tobacco smoke with perinatal death p value 0.579 (p> 0.05). Confounding variables that had no significant difference between the case and control groups were parity (p = 0.116, p> 0.05), education (p = 0.083, p> 0.05), birth distance (p = 0.26, p> 0.05), and birth attendants (p = 0.492, p> 0.05). Based on the results of these studies it can be concluded that exposure tobacco smoke in pregnant women is not associated with perinatal death and the main source of exposure tobacco smoke in pregnant women comes from home and at most from husbands. Keywords: exposure tobacco smoke, pregnant women, perinatal death
{"title":"The Relationship between Exposure Tobacco Smoke in Pregnant Women with Perinatal Death in Jember Regency","authors":"Reny Ekawati, S. Supangat, Hairrudin Hairrudin","doi":"10.19184/ams.v5i3.9610","DOIUrl":"https://doi.org/10.19184/ams.v5i3.9610","url":null,"abstract":"Perinatal death is an indicator of the success implementing a country's health services. Perinatal death rate in Indonesia in 2012 was 26/1000 live births. In 2017 there were 225 cases of infant mortality from 34,669 births in Jember Regency. Perinatal death is influenced by maternal, infant, health services and the living environment. The environmental conditions of the residence can be affected by cigarette smoke. The aim of this study was to determine the relationship of exposure tobacco smoke in pregnant women with perinatal death in Jember Regency and to find out the main source of exposure tobacco smoke in pregnant women in Jember Regency. Type of research is analytic observation with case control study design. The sampling technique is consecutive sampling. The study sample was mothers who had a dead baby in the perinatal period (perinatal death) who resided in the Jember regency on the birth of January-December 2017. The sample size was 30 for each group. Collected data was carried out by univariate analysis and bivariate analysis using the chi-square test and fisher exact test if the chi-square test requirements were not met. Results of univariate analysis in this study showed that 89.47% of the main sources of exposure tobacco smoke originated from home and 73.68% from husbands. Results of the chi-square test between exposure tobacco smoke with perinatal death p value 0.579 (p> 0.05). Confounding variables that had no significant difference between the case and control groups were parity (p = 0.116, p> 0.05), education (p = 0.083, p> 0.05), birth distance (p = 0.26, p> 0.05), and birth attendants (p = 0.492, p> 0.05). Based on the results of these studies it can be concluded that exposure tobacco smoke in pregnant women is not associated with perinatal death and the main source of exposure tobacco smoke in pregnant women comes from home and at most from husbands. \u0000 \u0000Keywords: exposure tobacco smoke, pregnant women, perinatal death \u0000 ","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"272 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125481125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burn wound healing process consists of three phases of inflammation, proliferation and remodelling. The number of fibroblasts has increased during the proliferation phase. Oxidative stress in burn may disrupt proliferation through TGF-β inhibition, result in decreased number of fibroblasts and poor burn wound healing. Genistein in edamame seeds has anti-inflammatory, antibacterial and antioxidant properties. Edamame contains vitamins A, C, and E which is also have antioxidant properties. Edamame has been suggested to protect burn wound healing from oxidative stress. This study aimed to understand the effectiveness of edamame seed (Glycine max L. Merril) ethanolic extract (ED) to fibroblast count in second degree burn wound healing. This is true experimental research with post test only control group design. The study was conducted at University of Jember during November until December 2017. The sample of this research was 24 rat models of second degree burn which was made by attaching hot metal (60 ° C) for 5 seconds on the shaved back of the rats. The sample was divided into 6 groups with topical treatment, among others: positive control group (silver sulfadiazine), negative control group (Na CMC 0.5%), group with ED 20%, ED 40%, ED 60%, and ED 80%. Treatment was given for 15 days and skin sample was taken on the 16th day. Observation of the number of fibroblasts was done by taking pictures of histhologic preparations in Hematoxylin and Eosin staining under 400x magnification of light microscope. The number of fibroblast of each picture was processed using Image-J software. In one way ANOVA test, significance value of 0.011 (p≤0,05) indicated that there was at least a significant difference between 2 groups. LSD’s post hoc analysis showed that there was a significant difference in the group ED 20, 40, and 60% compared with negative control. Keyword: burn wound healing, vegetable soybean, genistein, fibroblast count, silver sulfadiazine
烧伤创面愈合过程包括炎症、增殖和重塑三个阶段。成纤维细胞的数量在增殖期增加。烧伤氧化应激可能通过抑制TGF-β破坏细胞增殖，导致成纤维细胞数量减少，烧伤创面愈合不良。毛豆种子中的染料木素具有抗炎、抗菌和抗氧化的特性。毛豆含有维生素A、C和E，它们也具有抗氧化的特性。毛豆被认为可以保护烧伤伤口免受氧化应激的影响。本研究旨在了解毛豆种子(Glycine max L. Merril)乙醇提取物(ED)对二度烧伤创面愈合成纤维细胞计数的影响。这是一项真正的实验研究，仅采用后测对照组设计。该研究于2017年11月至12月在Jember大学进行。本研究的样本为24只大鼠二度烧伤模型，将热金属(60°C)附着在大鼠剃光的背部上5秒制成。将样品分为6组，分别为阳性对照组(磺胺嘧啶银)、阴性对照组(钠CMC 0.5%)、ED组20%、ED组40%、ED组60%、ED组80%。治疗15 d，第16天取皮肤标本。在400倍光镜下，对苏木精和伊红染色的组织学制剂进行拍照，观察成纤维细胞的数量。使用Image-J软件对每张图片的成纤维细胞数量进行处理。单因素方差分析(one - way ANOVA)检验，显著性值为0.011 (p≤0.05)表示两组间差异至少有统计学意义。LSD的事后分析显示，与阴性对照相比，ED 20、40和60%组有显著差异。关键词:烧伤创面愈合，蔬菜大豆，染料木素，成纤维细胞计数，磺胺嘧啶银
{"title":"The Effectiveness of Edamame Seed (Glycine max L. Merril) Ethanolic Extract to Fibroblast Count on Second Degree Burn Wound Healing","authors":"Arifa Nur Hasanah, I. Sutejo, E. Suswati","doi":"10.19184/ams.v5i3.6831","DOIUrl":"https://doi.org/10.19184/ams.v5i3.6831","url":null,"abstract":"Burn wound healing process consists of three phases of inflammation, proliferation and remodelling. The number of fibroblasts has increased during the proliferation phase. Oxidative stress in burn may disrupt proliferation through TGF-β inhibition, result in decreased number of fibroblasts and poor burn wound healing. Genistein in edamame seeds has anti-inflammatory, antibacterial and antioxidant properties. Edamame contains vitamins A, C, and E which is also have antioxidant properties. Edamame has been suggested to protect burn wound healing from oxidative stress. This study aimed to understand the effectiveness of edamame seed (Glycine max L. Merril) ethanolic extract (ED) to fibroblast count in second degree burn wound healing. This is true experimental research with post test only control group design. The study was conducted at University of Jember during November until December 2017. The sample of this research was 24 rat models of second degree burn which was made by attaching hot metal (60 ° C) for 5 seconds on the shaved back of the rats. The sample was divided into 6 groups with topical treatment, among others: positive control group (silver sulfadiazine), negative control group (Na CMC 0.5%), group with ED 20%, ED 40%, ED 60%, and ED 80%. Treatment was given for 15 days and skin sample was taken on the 16th day. Observation of the number of fibroblasts was done by taking pictures of histhologic preparations in Hematoxylin and Eosin staining under 400x magnification of light microscope. The number of fibroblast of each picture was processed using Image-J software. In one way ANOVA test, significance value of 0.011 (p≤0,05) indicated that there was at least a significant difference between 2 groups. LSD’s post hoc analysis showed that there was a significant difference in the group ED 20, 40, and 60% compared with negative control. \u0000 \u0000Keyword: burn wound healing, vegetable soybean, genistein, fibroblast count, silver sulfadiazine","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123748363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Water is a good medium for bacterial growth, so that contamination is happening especially if less attention in terms of hygiene and sanitation. The use of bed water sources can increase the risk of diarrhea. Diarrhea is one of the environmentally based disease is a major cause of morbidity and mortality. Kampung Baru village located around Jagir Kali Surabaya Most people are in the middle to low socioeconomic level. The lifestyle of them, also pays less attention to environmental hygiene and sanitation, so that it can cause water pollution which can increase the risk of diarrhea. This study was an observational analytic cross sectional study. Entire study population villagers of Kampung Baru. A sample of 75 respondents drawn with simple random sampling technique. The data used is primary data obtained through the distribution of questionnaires, interviews, and observations. Data analysis using the Spearman rank test with a significance level (α = 0.1). The results showed that 53,3% affected diarrhea and 46,7% didn’t affected (P =0.087, r=0.463). The results showed a medium correlation between the source of water with the incidence of diarrhea in Kampung Baru Resident At Ngagelrejo Wonokromo Surabaya. Keyword : Diarrhae, Water Sanitation
{"title":"The Relationship Between Clean Water Sources And The Incidence Of Diarrhea In Kampung Baru Resident At Ngagelrejo Wonokromo Surabaya","authors":"I. M. S. Harsa","doi":"10.19184/ams.v5i3.13813","DOIUrl":"https://doi.org/10.19184/ams.v5i3.13813","url":null,"abstract":"Abstract \u0000Water is a good medium for bacterial growth, so that contamination is happening especially if less attention in terms of hygiene and sanitation. The use of bed water sources can increase the risk of diarrhea. Diarrhea is one of the environmentally based disease is a major cause of morbidity and mortality. Kampung Baru village located around Jagir Kali Surabaya Most people are in the middle to low socioeconomic level. The lifestyle of them, also pays less attention to environmental hygiene and sanitation, so that it can cause water pollution which can increase the risk of diarrhea. This study was an observational analytic cross sectional study. Entire study population villagers of Kampung Baru. A sample of 75 respondents drawn with simple random sampling technique. The data used is primary data obtained through the distribution of questionnaires, interviews, and observations. Data analysis using the Spearman rank test with a significance level (α = 0.1). The results showed that 53,3% affected diarrhea and 46,7% didn’t affected (P =0.087, r=0.463). The results showed a medium correlation between the source of water with the incidence of diarrhea in Kampung Baru Resident At Ngagelrejo Wonokromo Surabaya. \u0000Keyword : Diarrhae, Water Sanitation","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127107174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soil-transmitted Helminths (STH) is a group of worms whose life cycle through the soil. The species of STH are roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura), hookworms (Necator americanus and Ancylostoma duodenale), and Strongyloides stercoralis. STH causes helminthiasis that infects more than 1.5 billion people or 24% of the world's population. Jember has many plantation areas. One of the plantations in Jember is Garahan Kidul plantation located in Sidomulyo village, Silo Sub-district, Jember. Soil on plantations tends to be moist and loose. This condition is ideal for the development of STH eggs and larvae. The general purpose of this study was to differentiate the numbers of soil contamination by STH eggs and larvae in soil samples in the garden area, riverside, and worker housing taken in the coffee plantation area in Silo District, Jember. This type of research is observational analytic with cross sectional research design. Soil samples are taken in the garden area, riverside, and worker housing that has a loose or not hard and moist soil texture. The results of the observation found that there were 4 eggs of Ascaris lumbricoides, 6 eggs and larvae of hookworm, and 2 eggs and larvae of Strongyloides stercoralis. There is the same amount of soil contamination at the location of the garden and riverside, which are 2 positive samples or 5.71% with a density of 0.02 eggs and larvae / gram of soil, while the number of soil contamination at the workers housing location is 8 positive samples or 25.71 % with a density of 0.11 eggs and larvae / gram of soil. Data were analyzed using Fisher's test. The results of data analysis showed a value of p = 0.0693 (p> 0.05) so that there were no differences in the number of soil contamination by STH eggs and larvae in the garden and river bank locations and p = 0.042 (p <0.05) so that there were differences the number of soil contamination by STH eggs and larvae at the location of worker housing with the location of garden and riverside. Keywords: STH, garden, riverside, wooker housing
{"title":"Difference between Location of Soil with Risk of Contamination of Soil-transmitted Helmints Eggs and Larvae (Observational Study of Coffee Plantation Area in Silo District, Jember Regency)","authors":"Rezza Putri Mahartika, Yunita Armiyanti, Cholis Abrori","doi":"10.19184/ams.v5i3.9468","DOIUrl":"https://doi.org/10.19184/ams.v5i3.9468","url":null,"abstract":"Soil-transmitted Helminths (STH) is a group of worms whose life cycle through the soil. The species of STH are roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura), hookworms (Necator americanus and Ancylostoma duodenale), and Strongyloides stercoralis. STH causes helminthiasis that infects more than 1.5 billion people or 24% of the world's population. Jember has many plantation areas. One of the plantations in Jember is Garahan Kidul plantation located in Sidomulyo village, Silo Sub-district, Jember. Soil on plantations tends to be moist and loose. This condition is ideal for the development of STH eggs and larvae. The general purpose of this study was to differentiate the numbers of soil contamination by STH eggs and larvae in soil samples in the garden area, riverside, and worker housing taken in the coffee plantation area in Silo District, Jember. This type of research is observational analytic with cross sectional research design. Soil samples are taken in the garden area, riverside, and worker housing that has a loose or not hard and moist soil texture. The results of the observation found that there were 4 eggs of Ascaris lumbricoides, 6 eggs and larvae of hookworm, and 2 eggs and larvae of Strongyloides stercoralis. There is the same amount of soil contamination at the location of the garden and riverside, which are 2 positive samples or 5.71% with a density of 0.02 eggs and larvae / gram of soil, while the number of soil contamination at the workers housing location is 8 positive samples or 25.71 % with a density of 0.11 eggs and larvae / gram of soil. Data were analyzed using Fisher's test. The results of data analysis showed a value of p = 0.0693 (p> 0.05) so that there were no differences in the number of soil contamination by STH eggs and larvae in the garden and river bank locations and p = 0.042 (p <0.05) so that there were differences the number of soil contamination by STH eggs and larvae at the location of worker housing with the location of garden and riverside. \u0000Keywords: STH, garden, riverside, wooker housing","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"13 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127004159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：