Pub Date : 2022-01-01DOI: 10.21608/smj.2022.118317.1301
M. Abu El-Hamd, Shereen Abd Elaa, A. Abdelwahab
: Postherpetic neuralgia (PHN) is defined as a neuropathic pain (NP) that continues from months to years after the cure of the herpes zoster (HZ) infection. The PHN is the main prevalent HZ complication. The incidence of PHN is 10% in people > 40 years old, 20%-50% of people > 60 years old, and scarcely reported in people < 30 years old and it enhances with increased age and reduced immunity. Consequently, it was mainly reported in the elders. The diagnosis of PHN is relatively straightforward. The pathophysiology of PHN is poorly understood; different pathophysiologic processes seem to be involved with the development of HZ and PHN. Also, many treatment modalities have been applied to reach maximum efficacy and tolerability. This review article aims to optimize the most recent and the most accepted concepts on the etiopathogenesis of PHN which may help in finding the best lines of management with the most satisfactory outcomes.
{"title":"Postherpetic neuralgia: an update of etiopathogenesis.","authors":"M. Abu El-Hamd, Shereen Abd Elaa, A. Abdelwahab","doi":"10.21608/smj.2022.118317.1301","DOIUrl":"https://doi.org/10.21608/smj.2022.118317.1301","url":null,"abstract":": Postherpetic neuralgia (PHN) is defined as a neuropathic pain (NP) that continues from months to years after the cure of the herpes zoster (HZ) infection. The PHN is the main prevalent HZ complication. The incidence of PHN is 10% in people > 40 years old, 20%-50% of people > 60 years old, and scarcely reported in people < 30 years old and it enhances with increased age and reduced immunity. Consequently, it was mainly reported in the elders. The diagnosis of PHN is relatively straightforward. The pathophysiology of PHN is poorly understood; different pathophysiologic processes seem to be involved with the development of HZ and PHN. Also, many treatment modalities have been applied to reach maximum efficacy and tolerability. This review article aims to optimize the most recent and the most accepted concepts on the etiopathogenesis of PHN which may help in finding the best lines of management with the most satisfactory outcomes.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"166 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132741215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/smj.2022.114037.1297
M. A. Ali, H. Ahmed, Ahmed Mahmoud, Dina Monir, R. Refaie, Khaled Abdelsater
Sleep is a universal phenomenon that is observed not only in humans but also in birds, fishes, and flies even in simpler organisms such as worms also we spend about 8 hours each day in sleep which represents nearly one-third of our life. All these observations indicate the physiological importance of sleep. study of sleep mechanisms requires the first study of the mechanisms, neurocircuits, and neurotransmitters involved in the promotion of wakefulness. Observation of Von Economo in 1930 of patients affected by “encephalitis lethargica”, an epidemic that causes widespread and prolonged sleepiness most of the day, opened the door for the study of the brain regions responsible for wakefulness. Researchers recognized now many brain regions that are responsible for wakefulness and other brain regions responsible for the induction of different types of sleep. This review will try to discuss the most recent mechanisms and neural circuits involved in the promotion of wakefulness.
{"title":"Updates Regarding Neurocircuits and Neurotransmitters Involved in the Regulation of Wakefulness","authors":"M. A. Ali, H. Ahmed, Ahmed Mahmoud, Dina Monir, R. Refaie, Khaled Abdelsater","doi":"10.21608/smj.2022.114037.1297","DOIUrl":"https://doi.org/10.21608/smj.2022.114037.1297","url":null,"abstract":"Sleep is a universal phenomenon that is observed not only in humans but also in birds, fishes, and flies even in simpler organisms such as worms also we spend about 8 hours each day in sleep which represents nearly one-third of our life. All these observations indicate the physiological importance of sleep. study of sleep mechanisms requires the first study of the mechanisms, neurocircuits, and neurotransmitters involved in the promotion of wakefulness. Observation of Von Economo in 1930 of patients affected by “encephalitis lethargica”, an epidemic that causes widespread and prolonged sleepiness most of the day, opened the door for the study of the brain regions responsible for wakefulness. Researchers recognized now many brain regions that are responsible for wakefulness and other brain regions responsible for the induction of different types of sleep. This review will try to discuss the most recent mechanisms and neural circuits involved in the promotion of wakefulness.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129983727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/smj.2022.179870.1357
Amira S Ahmed, Asmaa Thabet, Mamdouh M. Esmat
: Emerging pathogens known as multidrug-resistant (MDR) bacteria have resistance characteristics that have a major negative impact on human health. The emergence of microbes resistant to currently available medications has been influenced by the misuse of antibiotics. A number of methods, such as the change of antibiotics, the alteration of target sites, and the production of biofilms, are used by pathogenic bacteria to build resistance. Healthcare professionals are very concerned about bacterial colonization on surfaces in the form of biofilms because it can lead to chronic infections. It is currently urgently needed in both medicine and industry to create novel defenses against the growth of biofilms and planktonic infections, particularly strains that are resistant to antibiotics. The use of nanoparticles could be a potential solution in case of ineffectiveness of conventional methods for eliminating biofilms and the rising issue of antibiotic resistance. Metal oxide nanoparticles, like copper oxide, are among the many nanoparticles (NPs) that have attracted the greatest attention and promise. Existing biofilms are encouraged to be destroyed by copper oxide nanoparticles, which also inhibit formation of new ones. The primary cause is the toxicity of copper ions for plankton and biofilm cells. Many metal oxide nanoparticles have shown biological characteristics that are significantly more favorable than those of the parent metals NPs. For this reason, the metal oxide NPs sparked the most interest from scientific community.
{"title":"Copper Oxide Nanoparticles' Anti-biofilm Activity against MDR Gram negative bacilli","authors":"Amira S Ahmed, Asmaa Thabet, Mamdouh M. Esmat","doi":"10.21608/smj.2022.179870.1357","DOIUrl":"https://doi.org/10.21608/smj.2022.179870.1357","url":null,"abstract":": Emerging pathogens known as multidrug-resistant (MDR) bacteria have resistance characteristics that have a major negative impact on human health. The emergence of microbes resistant to currently available medications has been influenced by the misuse of antibiotics. A number of methods, such as the change of antibiotics, the alteration of target sites, and the production of biofilms, are used by pathogenic bacteria to build resistance. Healthcare professionals are very concerned about bacterial colonization on surfaces in the form of biofilms because it can lead to chronic infections. It is currently urgently needed in both medicine and industry to create novel defenses against the growth of biofilms and planktonic infections, particularly strains that are resistant to antibiotics. The use of nanoparticles could be a potential solution in case of ineffectiveness of conventional methods for eliminating biofilms and the rising issue of antibiotic resistance. Metal oxide nanoparticles, like copper oxide, are among the many nanoparticles (NPs) that have attracted the greatest attention and promise. Existing biofilms are encouraged to be destroyed by copper oxide nanoparticles, which also inhibit formation of new ones. The primary cause is the toxicity of copper ions for plankton and biofilm cells. Many metal oxide nanoparticles have shown biological characteristics that are significantly more favorable than those of the parent metals NPs. For this reason, the metal oxide NPs sparked the most interest from scientific community.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116187544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/smj.2022.173745.1354
Hend G. Aref, Ahmed Said, E. Ahmed, Mai Abdelkader, A. Elkady, Soheir K. Mohamed
: Nanotechnology is one of the fastest-growing and most promising modern technologies. It deals with the manufacturing and use of nanoparticles. Nanoparticles are generally known as small-sized particles possessing a size range of 1 to 100 nm. Due to their distinctive physicochemical and mechanical characteristics, they are utilized in various fields like agriculture, material science, food industry, medical, diagnostic, and cosmetic applications. One of the nanoparticles that is most frequently used nowadays is Zinc oxide nanoparticles. They have been explored for numerous biomedical applications, such as drug delivery, anticancer, antibacterial, antidiabetic, and bioimaging. Researchers expect that usage of Zinc oxide nanoparticles will expand so; the human body's exposure to them will increase. Zinc oxide .nanoparticles released into the environment could lead to adverse human and animal health effects. Recent studies concluded that Zinc oxide nanoparticles could cross some blood vital organs barriers and cell membranes, generate free radicals, and exhibit oxidative stress, cytotoxicity, and genotoxicity. Therefore, great attention must be taken to assess the toxicological aspects of nanoparticles.
{"title":"Biomedical Applications and Toxicological Aspects of Zinc Oxide Nanoparticles: A Review Article","authors":"Hend G. Aref, Ahmed Said, E. Ahmed, Mai Abdelkader, A. Elkady, Soheir K. Mohamed","doi":"10.21608/smj.2022.173745.1354","DOIUrl":"https://doi.org/10.21608/smj.2022.173745.1354","url":null,"abstract":": Nanotechnology is one of the fastest-growing and most promising modern technologies. It deals with the manufacturing and use of nanoparticles. Nanoparticles are generally known as small-sized particles possessing a size range of 1 to 100 nm. Due to their distinctive physicochemical and mechanical characteristics, they are utilized in various fields like agriculture, material science, food industry, medical, diagnostic, and cosmetic applications. One of the nanoparticles that is most frequently used nowadays is Zinc oxide nanoparticles. They have been explored for numerous biomedical applications, such as drug delivery, anticancer, antibacterial, antidiabetic, and bioimaging. Researchers expect that usage of Zinc oxide nanoparticles will expand so; the human body's exposure to them will increase. Zinc oxide .nanoparticles released into the environment could lead to adverse human and animal health effects. Recent studies concluded that Zinc oxide nanoparticles could cross some blood vital organs barriers and cell membranes, generate free radicals, and exhibit oxidative stress, cytotoxicity, and genotoxicity. Therefore, great attention must be taken to assess the toxicological aspects of nanoparticles.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130685613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/smj.2022.131134.1314
A. Mostafa, Amany Abd Allah, Sahar Abd Alwahed, R. Hafez, Safenaz Hussien, R. Bakry
: Objective: To evaluate interleukin-4 (IL-4), and interferon-gamma (IFN-γ) levels in Systemic lupus erythematosus (SLE) cases in addition to evaluating the correlation of IFN-γ, and IL-4 with disease activity. Patients and Methods: This study recruited 60 adult SLE subjects and 60 healthy controls. Subjects underwent complete clinical examination, history taking, as well as evaluation of disease activity in cases with SLE via the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Determination of serum levels of IFN-γ, and IL-4 was done in controls as well as patients. Results: IFN-γ, and IL-4 levels were substantially elevated in the SLE cohort than in the controls. Furthermore, the IFN-γ level is significantly positively correlated with SLEDAI, with no link between SLEDAI as well as IL-4. Conclusion: Elevated IFN-γ and IL-4 serum levels in cases with SLE play a role in SLE progression and have a role in disease activity. IFN-γ serum levels were positively linked with disease activity and anti-dsDNA, negatively linked with C4, and no significant correlation with C3 and 24 h protein in the urine.
{"title":"Interleukin-4, and interferon-gamma roles as biomarkers in Systemic Lupus Erythematosus patients.","authors":"A. Mostafa, Amany Abd Allah, Sahar Abd Alwahed, R. Hafez, Safenaz Hussien, R. Bakry","doi":"10.21608/smj.2022.131134.1314","DOIUrl":"https://doi.org/10.21608/smj.2022.131134.1314","url":null,"abstract":": Objective: To evaluate interleukin-4 (IL-4), and interferon-gamma (IFN-γ) levels in Systemic lupus erythematosus (SLE) cases in addition to evaluating the correlation of IFN-γ, and IL-4 with disease activity. Patients and Methods: This study recruited 60 adult SLE subjects and 60 healthy controls. Subjects underwent complete clinical examination, history taking, as well as evaluation of disease activity in cases with SLE via the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Determination of serum levels of IFN-γ, and IL-4 was done in controls as well as patients. Results: IFN-γ, and IL-4 levels were substantially elevated in the SLE cohort than in the controls. Furthermore, the IFN-γ level is significantly positively correlated with SLEDAI, with no link between SLEDAI as well as IL-4. Conclusion: Elevated IFN-γ and IL-4 serum levels in cases with SLE play a role in SLE progression and have a role in disease activity. IFN-γ serum levels were positively linked with disease activity and anti-dsDNA, negatively linked with C4, and no significant correlation with C3 and 24 h protein in the urine.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"55 13","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120902743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/smj.2023.186994.1364
Farida S. Abdou, E. Mohamed, A. Ghaleb, Samir A. Abdelmageed
{"title":"Nutritional consequences of bariatric surgery Samir Ahmed Abdelmageed1, Eman Roshdy Mohamed2, Alaa Ahmed Ghaleb3, Farida Sami Abdou4 4Family Medicine department, Faculty of medicine, Sohag University 1General surgery department, Faculty of Medic","authors":"Farida S. Abdou, E. Mohamed, A. Ghaleb, Samir A. Abdelmageed","doi":"10.21608/smj.2023.186994.1364","DOIUrl":"https://doi.org/10.21608/smj.2023.186994.1364","url":null,"abstract":"","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"212 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132470269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/smj.2022.100213.1275
M. Noaman
{"title":"Diagnostic Value of diffusion-weighted MR and MR spectroscopy in the differentiation of benign from malignant breast lesions : An Updated review of literature","authors":"M. Noaman","doi":"10.21608/smj.2022.100213.1275","DOIUrl":"https://doi.org/10.21608/smj.2022.100213.1275","url":null,"abstract":"","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"175 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125805575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/smj.2022.107374.1286
noreen Abdelghany, ramdan abdo, Wafaa Abdelmaged
{"title":"Microneedling in treatment of vitiligo: a review article","authors":"noreen Abdelghany, ramdan abdo, Wafaa Abdelmaged","doi":"10.21608/smj.2022.107374.1286","DOIUrl":"https://doi.org/10.21608/smj.2022.107374.1286","url":null,"abstract":"","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116481567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.21608/smj.2021.79201.1257
Y. Amin
{"title":"The neuroimaging findings in CO-VID-19 patients A literature review","authors":"Y. Amin","doi":"10.21608/smj.2021.79201.1257","DOIUrl":"https://doi.org/10.21608/smj.2021.79201.1257","url":null,"abstract":"","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131990574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.21608/smj.2021.87546.1270
Ghada Borham
Introduction and aim of work: Focal segmental glomerulosclerosis is the commonest underlying histopathological diagnosis in idiopathic steroid-resistant nephrotic syndrome in children. Many immunosuppressive therapies are used in its treatment. There is a 50% risk of progression to end-stage renal disease within five years if there is no complete or even partial remission with immunomodulatory therapies. This work aimed to study the various clinical, histopathological and therapeutic aspects of idiopathic steroid-resistant nephrotic syndrome in our locality. Patients and Methods: This retrospective study was conducted on children aged 1 – 15 years with idiopathic steroid-resistant nephrotic syndrome, followed in our Pediatric Nephrology Clinic in Sohag University Hospital, between January 2002 and January 2017. Patients' demographic features and disease's clinical course, histopathological patterns, response to various medications, and long-term outcomes were evaluated. Results: There were 28 patients with initial and 5 with late steroid resistance. The mean age at disease onset was 3.98±3.14 years. The male/female ratio was 2.5/1. Renal biopsy was performed in 26 patients. Minimal change disease was present in 5 patients, mesangioproliferative glomerulonephritis in 6 patients, and focal segmental glomerulosclerosis in 15 patients. Fifteen patients received cyclophosphamide, 26 received cyclosporine, 8 used mycophenolate mofetil, and 4 received combined immunosuppressive therapies. Four patients developed end-stage kidney disease. There were five deaths by the end of the study. Conclusion: In our study, focal segmental glomerulosclerosis is the most common histopathology in idiopathic steroid-resistant nephrotic syndrome and cyclosporine is the most effective second-line therapy in those patients
{"title":"Clinico-pathological patterns of Childhood idiopathic steroid-resistant nephrotic syndrome: a retrospective single-center experience","authors":"Ghada Borham","doi":"10.21608/smj.2021.87546.1270","DOIUrl":"https://doi.org/10.21608/smj.2021.87546.1270","url":null,"abstract":"Introduction and aim of work: Focal segmental glomerulosclerosis is the commonest underlying histopathological diagnosis in idiopathic steroid-resistant nephrotic syndrome in children. Many immunosuppressive therapies are used in its treatment. There is a 50% risk of progression to end-stage renal disease within five years if there is no complete or even partial remission with immunomodulatory therapies. This work aimed to study the various clinical, histopathological and therapeutic aspects of idiopathic steroid-resistant nephrotic syndrome in our locality. Patients and Methods: This retrospective study was conducted on children aged 1 – 15 years with idiopathic steroid-resistant nephrotic syndrome, followed in our Pediatric Nephrology Clinic in Sohag University Hospital, between January 2002 and January 2017. Patients' demographic features and disease's clinical course, histopathological patterns, response to various medications, and long-term outcomes were evaluated. Results: There were 28 patients with initial and 5 with late steroid resistance. The mean age at disease onset was 3.98±3.14 years. The male/female ratio was 2.5/1. Renal biopsy was performed in 26 patients. Minimal change disease was present in 5 patients, mesangioproliferative glomerulonephritis in 6 patients, and focal segmental glomerulosclerosis in 15 patients. Fifteen patients received cyclophosphamide, 26 received cyclosporine, 8 used mycophenolate mofetil, and 4 received combined immunosuppressive therapies. Four patients developed end-stage kidney disease. There were five deaths by the end of the study. Conclusion: In our study, focal segmental glomerulosclerosis is the most common histopathology in idiopathic steroid-resistant nephrotic syndrome and cyclosporine is the most effective second-line therapy in those patients","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124998228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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