Pub Date : 2024-05-01DOI: 10.21608/smj.2024.272599.1457
Noha Mahmoud, Ahmed Ahmed, Omar Ali, Alaa Radwan
Background: The current gold standard for treating breast cancer is a combination of radiation and breast oncoplastic treatments. When treating malignancies in the top quadrants of big, ptotic breasts, inferior pedicle mammoplasty allows for extensive quadrantectomies to be conducted without changing the breast's natural shape or reducing the amount of breast volume that may be irradiated. Aesthetically attractive tumor removal with substantial safety margins is the goal of therapeutic mammoplasty. The aim of this study: Its purpose is to treat early-stage breast cancer in women with big breasts using the inferior pedicle therapeutic mammoplasty technique. Methods: This research comprised fifteen large-breasted women who were diagnosed with early breast cancer during the months of June 2019 and June 2021. Results: The patients' ages varied from 31 to 57 years (median 49.7), and the tumor sizes ranged from one to three and a half centimeters. The weight of the excised tissue ranged from 350 grams to 780 grams, while the tumor safety margins varied between three and eight centimeters. A patient had a straightforward mastectomy because to the presence of infiltrative margin measuring 7.14%. The most frequent consequences after surgery are inflammation and wound infection, affecting two patients (14.28%). In one instance (7.14%), cancer recurred and required a broad local incision. Out of the total number of patients, 10 individuals (71.4%) had an exceptional cosmetic outcome. One patient (7.1%) had good results, while two patients (14.3%) reported passable outcomes. Unfortunately, one patient (7.1%) experienced a negative result. The duration of the follow-up period ranges from 6 to 42 months. Conclusion: The use of the inferior pedicle therapeutic reduction mammoplasty technique is a safe and effective surgical treatment for treating early breast cancer in women with big breasts. This operation not only addresses the oncological aspects but also provides a pleasing cosmetic result.
{"title":"Assessment of inferior pedicle therapeutic mammoplasty as apart of volume displacement techniques of oncoplastic breast surgery for early breast cancer","authors":"Noha Mahmoud, Ahmed Ahmed, Omar Ali, Alaa Radwan","doi":"10.21608/smj.2024.272599.1457","DOIUrl":"https://doi.org/10.21608/smj.2024.272599.1457","url":null,"abstract":"Background: The current gold standard for treating breast cancer is a combination of radiation and breast oncoplastic treatments. When treating malignancies in the top quadrants of big, ptotic breasts, inferior pedicle mammoplasty allows for extensive quadrantectomies to be conducted without changing the breast's natural shape or reducing the amount of breast volume that may be irradiated. Aesthetically attractive tumor removal with substantial safety margins is the goal of therapeutic mammoplasty. The aim of this study: Its purpose is to treat early-stage breast cancer in women with big breasts using the inferior pedicle therapeutic mammoplasty technique. Methods: This research comprised fifteen large-breasted women who were diagnosed with early breast cancer during the months of June 2019 and June 2021. Results: The patients' ages varied from 31 to 57 years (median 49.7), and the tumor sizes ranged from one to three and a half centimeters. The weight of the excised tissue ranged from 350 grams to 780 grams, while the tumor safety margins varied between three and eight centimeters. A patient had a straightforward mastectomy because to the presence of infiltrative margin measuring 7.14%. The most frequent consequences after surgery are inflammation and wound infection, affecting two patients (14.28%). In one instance (7.14%), cancer recurred and required a broad local incision. Out of the total number of patients, 10 individuals (71.4%) had an exceptional cosmetic outcome. One patient (7.1%) had good results, while two patients (14.3%) reported passable outcomes. Unfortunately, one patient (7.1%) experienced a negative result. The duration of the follow-up period ranges from 6 to 42 months. Conclusion: The use of the inferior pedicle therapeutic reduction mammoplasty technique is a safe and effective surgical treatment for treating early breast cancer in women with big breasts. This operation not only addresses the oncological aspects but also provides a pleasing cosmetic result.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"126 S1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141034998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.260399.1440
Raghda Hassan, Marwa Abu elmagd, Mohammed Abu El-Hamd, Essam Nada
{"title":"Updates on etiopathogenesis and management of planter warts.","authors":"Raghda Hassan, Marwa Abu elmagd, Mohammed Abu El-Hamd, Essam Nada","doi":"10.21608/smj.2024.260399.1440","DOIUrl":"https://doi.org/10.21608/smj.2024.260399.1440","url":null,"abstract":"","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"22 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141031335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.259587.1439
Enas Abuzied, Hamdy A. Mohammadien, Ashraf El Abidien, Khaled Alkhayat
Pulmonary embolism (PE) is considered one of the serious cardiovascular emergencies that will increase the mortality if complicated with unstable hemodynamics. Because of its nonspecific clinical symptoms, it’s a great challenge to make a PE diagnosis. The gold standard in its diagnosis is computed tomography pulmonary angiography (CTPA). Thoracic Ultrasound (TUS) may serve as a simple, non-invasive, and an accurate imaging modality that can be rapidly performed for immobile and critically ill patients as a bedside test for early detection of PE Aim: Highlight the role of Thoracic Ultrasonography in diagnosis of Pulmonary Embolism Results: This study included 58 patients suspected to have pulmonary embolism clinically. 40 out of 58 patients finally diagnosed as PE by CTPA. In comparison to the CTPA, TUS was found true positive in 30 patients, false positive in 8 patients, true negative in 10 patients, and false negative in 10 patients, the sensitivity was 75%, the specificity was 55%. Positive and negative predictive value was 78.9% and 50% respectively with the accuracy was 69% Conclusion: TUS has a promising role in the evaluation of PE. It is a safe, non-invasive imaging modality that is readily available for use at the bedside in critically ill patient.
{"title":"The Promising Role of Thoracic Ultrasonography in Diagnosis of Pulmonary Embolism","authors":"Enas Abuzied, Hamdy A. Mohammadien, Ashraf El Abidien, Khaled Alkhayat","doi":"10.21608/smj.2024.259587.1439","DOIUrl":"https://doi.org/10.21608/smj.2024.259587.1439","url":null,"abstract":"Pulmonary embolism (PE) is considered one of the serious cardiovascular emergencies that will increase the mortality if complicated with unstable hemodynamics. Because of its nonspecific clinical symptoms, it’s a great challenge to make a PE diagnosis. The gold standard in its diagnosis is computed tomography pulmonary angiography (CTPA). Thoracic Ultrasound (TUS) may serve as a simple, non-invasive, and an accurate imaging modality that can be rapidly performed for immobile and critically ill patients as a bedside test for early detection of PE Aim: Highlight the role of Thoracic Ultrasonography in diagnosis of Pulmonary Embolism Results: This study included 58 patients suspected to have pulmonary embolism clinically. 40 out of 58 patients finally diagnosed as PE by CTPA. In comparison to the CTPA, TUS was found true positive in 30 patients, false positive in 8 patients, true negative in 10 patients, and false negative in 10 patients, the sensitivity was 75%, the specificity was 55%. Positive and negative predictive value was 78.9% and 50% respectively with the accuracy was 69% Conclusion: TUS has a promising role in the evaluation of PE. It is a safe, non-invasive imaging modality that is readily available for use at the bedside in critically ill patient.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"24 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141049663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.268250.1453
mohammed morsi, Nayel Zaki, Usama Arafa, Ahmed Hussein
Background: due to abnormalities in coagulation and hypo-fibrinolysis, diabetes mellitus is linked to an increased risk of thrombotic complications. In patients with chronic kidney disease (CKD), pro-and anti-hemostatic factors are disrupted, leading to both bleeding and thrombotic complications. However, few studies have shown how diabetes mellitus affects serum fibrinogen levels and APTT in non-dialysis CKD patients. Aim of the work: To investigate impact of type 2 DM on APTT and serum fibrinogen in Non-dialysis CKD patients. Patients and methods: 150 patients classified into 3 groups each group included 50 patients, group with DM only patients, group with CKD only patients and group with CKD and DM patients , demographic data, APTT, serum fibrinogen , HbA1c and eGFR were done for all patients. Results: Combining DM with CKD led to a significant increase in serum fibrinogen level (p<0.0001) and a reduction in APTT (p<0.0001). Serum fibrinogen also showed a positive correlation with HbA1c and eGFR (p<0.0001, r = 0.8) (P <0.002, r = 0.26) and a negative correlation (P<0.0001, r = -0.66) ( P< 0.0001, r = - 0.50) with HbA1c and eGFR. Conclusion: Serum fibrinogen, APTT, and glycemic state should all be closely watched in non-dialysis CKD patients. This can help lower the risk of thrombosis in the future.
{"title":"Impact Of Type 2 Diabetes Mellitus On Activated Partial Thromboplastin Time and Serum Fibrinogen In Non-dialysis Chronic Kidney Disease Patients","authors":"mohammed morsi, Nayel Zaki, Usama Arafa, Ahmed Hussein","doi":"10.21608/smj.2024.268250.1453","DOIUrl":"https://doi.org/10.21608/smj.2024.268250.1453","url":null,"abstract":"Background: due to abnormalities in coagulation and hypo-fibrinolysis, diabetes mellitus is linked to an increased risk of thrombotic complications. In patients with chronic kidney disease (CKD), pro-and anti-hemostatic factors are disrupted, leading to both bleeding and thrombotic complications. However, few studies have shown how diabetes mellitus affects serum fibrinogen levels and APTT in non-dialysis CKD patients. Aim of the work: To investigate impact of type 2 DM on APTT and serum fibrinogen in Non-dialysis CKD patients. Patients and methods: 150 patients classified into 3 groups each group included 50 patients, group with DM only patients, group with CKD only patients and group with CKD and DM patients , demographic data, APTT, serum fibrinogen , HbA1c and eGFR were done for all patients. Results: Combining DM with CKD led to a significant increase in serum fibrinogen level (p<0.0001) and a reduction in APTT (p<0.0001). Serum fibrinogen also showed a positive correlation with HbA1c and eGFR (p<0.0001, r = 0.8) (P <0.002, r = 0.26) and a negative correlation (P<0.0001, r = -0.66) ( P< 0.0001, r = - 0.50) with HbA1c and eGFR. Conclusion: Serum fibrinogen, APTT, and glycemic state should all be closely watched in non-dialysis CKD patients. This can help lower the risk of thrombosis in the future.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"55 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141042913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.264014.1445
Ghada Borham, Mahmoud Abd El-aal, mustafa abo-sdera, Rania Abdelatif
Background: Cyclosporine is a calcineurin inhibitor that exhibits a notable steroid-sparing effect in patients with steroid-dependent and frequent relapsing nephrotic syndrome. Despite long-term cyclosporine use, it has been linked to an increased risk of unpleasant side effects, including nephrotoxicity, hypertension, and cosmetic symptoms like hirsutism and gum hypertrophy. Aim: To assess the effectiveness and side effects of cyclosporine in children diagnosed with steroid-dependent and frequent relapsing nephrotic syndrome at Sohag University Hospital. Methods: This was a combined prospective and retrospective study which was conducted at Pediatric nephrology clinic, Sohag University Hospital on children diagnosed as steroid-dependent and frequent relapsing nephrotic syndrome who received cyclosporine as a steroid sparing agent. Results: This study included total 50 nephrotic patients, there mean age was 11.4 ± 3.1 (4-15) years. Male: female ratio was 2.8:1. The median disease duration was 7 years with interquartile range (3.88-9.63) years, and the median cyclosporine use duration was 4 years with interquartile range (1.5-6) years. The average relapse number/patient/year significantly decreased by 82.6% following cyclosporine treatment, and the mean dependent steroid dose decreased by 69.19%.The recorded cyclosporine side effects were: hirsutism in 94%, gum hyperplasia in 38%, gastrointestinal disturbances in 32%, nephrotoxicity in 28% and new onset hypertension in 26% of cases. Histological nephrotoxicity was evident in 14 individuals (35.9%) of biopsied children. Conclusion: Cyclosporine is deemed both safe and efficacious as a steroid-sparing medication for individuals with steroid-dependent and frequent relapsing nephrotic syndrome. Nonetheless, the safety of cyclosporine is not without exceptions, and various levels of side effects have been documented.
{"title":"Cyclosporine effectiveness and adverse outcomes in steroid dependent and frequent relapsing nephrotic syndrome in children","authors":"Ghada Borham, Mahmoud Abd El-aal, mustafa abo-sdera, Rania Abdelatif","doi":"10.21608/smj.2024.264014.1445","DOIUrl":"https://doi.org/10.21608/smj.2024.264014.1445","url":null,"abstract":"Background: Cyclosporine is a calcineurin inhibitor that exhibits a notable steroid-sparing effect in patients with steroid-dependent and frequent relapsing nephrotic syndrome. Despite long-term cyclosporine use, it has been linked to an increased risk of unpleasant side effects, including nephrotoxicity, hypertension, and cosmetic symptoms like hirsutism and gum hypertrophy. Aim: To assess the effectiveness and side effects of cyclosporine in children diagnosed with steroid-dependent and frequent relapsing nephrotic syndrome at Sohag University Hospital. Methods: This was a combined prospective and retrospective study which was conducted at Pediatric nephrology clinic, Sohag University Hospital on children diagnosed as steroid-dependent and frequent relapsing nephrotic syndrome who received cyclosporine as a steroid sparing agent. Results: This study included total 50 nephrotic patients, there mean age was 11.4 ± 3.1 (4-15) years. Male: female ratio was 2.8:1. The median disease duration was 7 years with interquartile range (3.88-9.63) years, and the median cyclosporine use duration was 4 years with interquartile range (1.5-6) years. The average relapse number/patient/year significantly decreased by 82.6% following cyclosporine treatment, and the mean dependent steroid dose decreased by 69.19%.The recorded cyclosporine side effects were: hirsutism in 94%, gum hyperplasia in 38%, gastrointestinal disturbances in 32%, nephrotoxicity in 28% and new onset hypertension in 26% of cases. Histological nephrotoxicity was evident in 14 individuals (35.9%) of biopsied children. Conclusion: Cyclosporine is deemed both safe and efficacious as a steroid-sparing medication for individuals with steroid-dependent and frequent relapsing nephrotic syndrome. Nonetheless, the safety of cyclosporine is not without exceptions, and various levels of side effects have been documented.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"30 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141046335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.256370.1438
Rania Alkhalili, salah ismail, hazem mohammed, Mohamedmohammed Nour El-dien
{"title":"Does vitamin D deficiency have a role in resistance to ovulation induction in polycystic ovary syndrome patients?","authors":"Rania Alkhalili, salah ismail, hazem mohammed, Mohamedmohammed Nour El-dien","doi":"10.21608/smj.2024.256370.1438","DOIUrl":"https://doi.org/10.21608/smj.2024.256370.1438","url":null,"abstract":"","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"46 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141030167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.245375.1425
Hussein Ali, Gharib Fawi, Hassan Elnady, Mohamed Thabet, A. Amin
{"title":"Evoked Potentials and blink reflex patterns in patients with migraine without aura and frequent episodic tension-type headache. An overview.","authors":"Hussein Ali, Gharib Fawi, Hassan Elnady, Mohamed Thabet, A. Amin","doi":"10.21608/smj.2024.245375.1425","DOIUrl":"https://doi.org/10.21608/smj.2024.245375.1425","url":null,"abstract":"","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"11 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141034239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.251858.1430
ahmed aly khalifa, M. Ameen, Mostafa Abdelkhalek, mohammed khalafalla, Mahmoud Mousa, Wael Amer
: Background: Endometrial cancer is the commonest gynecological neoplasm in developed nations. The current study aimed at comparing, in a series of females the usefulness, security as well as morbidity of total Laparoscopic and Laparoscopic for early-stage EC. Methods: This prospective randomized study of 50 females with clinical stage I endometrial carcinoma. cases were classified into 2 equal groups: group 1 was managed by total LPS, and group 2 were treated with Laparoscopic. At admission, each woman was subjected to a gynecological and rectal examination, US and hysteroscopic evaluation. biopsies from the endometrium, chest X-ray, and MRI and/ or CT scan. LN dissection was done in selected patients in both groups. Results: Characteristics of the studied groups (Hb decline, blood loss and time of postoperative ileus) revealed significant reduction in the Laparoscopic group in comparison with Laparoscopic group. The incidence of fever revealed a significant decrease in Laparoscopic group compared to Laparoscopic group as well. Hospital stay and operative time were insignificantly different between the studied groups. The incidence of fever was significantly lower in Laparoscopic group compared to Laparoscopic group. Complications including (bladder and ureteric injuries, conversion to laparotomy, missed intestinal injury, postoperative hematoma, and wound infection) were insignificantly different between the studied groups. Conclusions: Laparoscopy is an appropriate method in treating early endometrial carcinoma .
:背景：子宫内膜癌是发达国家最常见的妇科肿瘤。本研究旨在比较全腹腔镜和腹腔镜治疗早期子宫内膜癌的实用性、安全性和发病率。方法：将病例分为两组：第一组采用全腹腔镜手术，第二组采用腹腔镜手术。入院时，每位女性都要接受妇科和直肠检查、美国和宫腔镜评估、子宫内膜活检、胸部 X 光检查、核磁共振成像和/或 CT 扫描。两组患者中均有选择地进行了 LN 切除术。结果研究组的特征（血红蛋白下降、失血量和术后回肠梗阻时间）显示，腹腔镜组比腹腔镜组明显减少。腹腔镜组与腹腔镜组相比，发热发生率也明显下降。研究组之间的住院时间和手术时间差异不大。腹腔镜组的发热发生率明显低于腹腔镜组。并发症（膀胱和输尿管损伤、转为开腹手术、肠道损伤、术后血肿和伤口感染）在研究组之间差异不大。结论腹腔镜是治疗早期子宫内膜癌的合适方法。
{"title":"Total Laparoscopic Hysterectomy with Laparoscopic Lymphadenectomy versus Conventional Abdominal Hysterectomy with Lymphadenectomy for Early-Stage Endometrial Cancer: A Prospective Randomized Study","authors":"ahmed aly khalifa, M. Ameen, Mostafa Abdelkhalek, mohammed khalafalla, Mahmoud Mousa, Wael Amer","doi":"10.21608/smj.2024.251858.1430","DOIUrl":"https://doi.org/10.21608/smj.2024.251858.1430","url":null,"abstract":": Background: Endometrial cancer is the commonest gynecological neoplasm in developed nations. The current study aimed at comparing, in a series of females the usefulness, security as well as morbidity of total Laparoscopic and Laparoscopic for early-stage EC. Methods: This prospective randomized study of 50 females with clinical stage I endometrial carcinoma. cases were classified into 2 equal groups: group 1 was managed by total LPS, and group 2 were treated with Laparoscopic. At admission, each woman was subjected to a gynecological and rectal examination, US and hysteroscopic evaluation. biopsies from the endometrium, chest X-ray, and MRI and/ or CT scan. LN dissection was done in selected patients in both groups. Results: Characteristics of the studied groups (Hb decline, blood loss and time of postoperative ileus) revealed significant reduction in the Laparoscopic group in comparison with Laparoscopic group. The incidence of fever revealed a significant decrease in Laparoscopic group compared to Laparoscopic group as well. Hospital stay and operative time were insignificantly different between the studied groups. The incidence of fever was significantly lower in Laparoscopic group compared to Laparoscopic group. Complications including (bladder and ureteric injuries, conversion to laparotomy, missed intestinal injury, postoperative hematoma, and wound infection) were insignificantly different between the studied groups. Conclusions: Laparoscopy is an appropriate method in treating early endometrial carcinoma .","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"8 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141041922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.262128.1447
A. Ahmed, Amr Adam, Adel Elsayed, A. Altaher
: Introduction: The risk of major complications is greatly increased by type 2 diabetes (T2D). By 2030, it is predicted that prevalence of type 2D will be dramatically increase in Egypt. Aim: is to assess the risk factors for T2D in Egyptian populations and try to design a more convenient Egyptian risk score for susceptibility to T2D. Patients & Methods : This study was conducted at Sohag University Hospital including 377 participants divided into 2 groups; study group included 161 recently discovered diabetics & healthy group 216 person. Results : Certain age groups, females, steroid intake, carbohydrate or fat diets, sedentary life, hypertension, family history of T2D, HCV, BMI > 25, those with waist circumference for males ≥ 90cm & for females ≥ 85cm were independent predictors for Univariate and Multivariate regression analysis of risk factors for newely discovered DM. A score of ≥13 points indicated a high risk for DM. The (ROC) curve illustrating how well the risk score predicted DM in the population studied ((AUC) = 0.82, 95% CI 0.78:0.86) and cutoff value >13 has a sensitivity of 70% and specificity of 85%. Conclusion : In the current study, a more convenient DM risk scoring model is designed specifically and appropriately for Egyptians. A score > 13 indicates a high risk for DM.
{"title":"Risk Factors of Recently Discovered Type II Diabetic Patients at Sohag University Hospitals","authors":"A. Ahmed, Amr Adam, Adel Elsayed, A. Altaher","doi":"10.21608/smj.2024.262128.1447","DOIUrl":"https://doi.org/10.21608/smj.2024.262128.1447","url":null,"abstract":": Introduction: The risk of major complications is greatly increased by type 2 diabetes (T2D). By 2030, it is predicted that prevalence of type 2D will be dramatically increase in Egypt. Aim: is to assess the risk factors for T2D in Egyptian populations and try to design a more convenient Egyptian risk score for susceptibility to T2D. Patients & Methods : This study was conducted at Sohag University Hospital including 377 participants divided into 2 groups; study group included 161 recently discovered diabetics & healthy group 216 person. Results : Certain age groups, females, steroid intake, carbohydrate or fat diets, sedentary life, hypertension, family history of T2D, HCV, BMI > 25, those with waist circumference for males ≥ 90cm & for females ≥ 85cm were independent predictors for Univariate and Multivariate regression analysis of risk factors for newely discovered DM. A score of ≥13 points indicated a high risk for DM. The (ROC) curve illustrating how well the risk score predicted DM in the population studied ((AUC) = 0.82, 95% CI 0.78:0.86) and cutoff value >13 has a sensitivity of 70% and specificity of 85%. Conclusion : In the current study, a more convenient DM risk scoring model is designed specifically and appropriately for Egyptians. A score > 13 indicates a high risk for DM.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"31 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141044125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.21608/smj.2024.245861.1427
Manar Sayed, Osama Mahmoud Ahmed, Ahmed Amin
Chronic obstructive pulmonary disease (COPD) and dementia are both extremely widespread chronic diseases with a significant impact on world health. The most common comorbidity of COPD is dementia, leading to an increased need for hospitalization, difficulties with daily functioning, an increased need for care services, and rate of mortality. 4% and 61% of patients with COPD reported developing cognitive impairment. Alteration in cerebral perfusion in patients with COPD results from hypoxemia, which is an abnormal decrease in oxygen in the blood, and these changes contribute to the development of cognitive decline. Long-term hypoxia, hypercapnia, and increased inflammatory cytokines in COPD patients contribute to the development of degenerative brain diseases (including structural changes in the brain and reduced white matter integrity). Psychomotor speed, planning, verbal memory, and cognitive flexibility are cognitive domains affected in patients with COPD. The risk of dementia increases with age but is unaffected by gender.
{"title":"Dementia in patients with chronic obstructive pulmonary disease Manar hamza sayed, Ahmed Ezzat Amin, Osama El Taher Mahmoud. 1. Department of Neuropsychiatry, Faculty of Medicine, Sohag University. faculty of medicine","authors":"Manar Sayed, Osama Mahmoud Ahmed, Ahmed Amin","doi":"10.21608/smj.2024.245861.1427","DOIUrl":"https://doi.org/10.21608/smj.2024.245861.1427","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) and dementia are both extremely widespread chronic diseases with a significant impact on world health. The most common comorbidity of COPD is dementia, leading to an increased need for hospitalization, difficulties with daily functioning, an increased need for care services, and rate of mortality. 4% and 61% of patients with COPD reported developing cognitive impairment. Alteration in cerebral perfusion in patients with COPD results from hypoxemia, which is an abnormal decrease in oxygen in the blood, and these changes contribute to the development of cognitive decline. Long-term hypoxia, hypercapnia, and increased inflammatory cytokines in COPD patients contribute to the development of degenerative brain diseases (including structural changes in the brain and reduced white matter integrity). Psychomotor speed, planning, verbal memory, and cognitive flexibility are cognitive domains affected in patients with COPD. The risk of dementia increases with age but is unaffected by gender.","PeriodicalId":254383,"journal":{"name":"Sohag Medical Journal","volume":"70 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141038680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：