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Wheat Septoria Disease Management and Molecular Breeding Approaches in Ethiopia: A Review 埃塞俄比亚的小麦七叶病管理和分子育种方法:综述
Pub Date : 2023-07-19 DOI: 10.23880/oajmb-16000273
Abdisa Ll
Septoria tritici blotch (STB) caused by the fungus Mycosphaerella graminicola, is one of the most important foliar diseases of wheat (T. aestivum spp., aestivum L.) worldwide. The disease is pervasive and economically significant throughout Ethiopia's wheat-growing regions. Naturally susceptible wheat cultivars of STB disease were found in the Central Highlands of Ethiopia, where incidence (98%) and severity (97%) of the disease, as well as yield loss (41%), were documented. This disease has been managed using a variety of techniques, including cultural control, chemical control, and genetic controls have been utilized to control this disease and subsequently reduce yield losses. The lack of information on the diversity of diseases worldwide and in Ethiopia now hampers the screening and selection of wheat genotypes for disease resistance. In this review, wheat septoria disease management and molecular breeding approaches in Ethiopia were assessed.
由真菌禾本科真菌(Mycosphaerella graminicola)引起的三尖孢(Septoria tritici)斑点病(STB)是全球小麦(T. aestivum spp.这种病害在埃塞俄比亚的小麦种植区普遍存在,具有重要的经济意义。在埃塞俄比亚中部高原地区发现了对 STB 病害天然易感的小麦品种,并记录了其发病率(98%)和严重程度(97%)以及产量损失(41%)。该病害的防治采用了多种技术,包括文化防治、化学防治和基因防治,以控制该病害,进而减少产量损失。目前,由于缺乏有关全球和埃塞俄比亚病害多样性的信息,阻碍了小麦抗病基因型的筛选和选育。本综述对埃塞俄比亚的小麦败酱病管理和分子育种方法进行了评估。
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引用次数: 0
Heavy Metal Concentrations in Commonly Sold Onions (Allium Cepa) and Probable Health Risk Assessment 常见洋葱(Allium Cepa)中的重金属浓度和可能的健康风险评估
Pub Date : 2023-07-19 DOI: 10.23880/oajmb-16000268
Chamon As
In this current research, samples of domestic and imported onions were collected from wholesale markets in Dhaka, Bangladesh, and their heavy metal concentrations were measured. Several health issues could arise from eating onions, according to estimations. After being randomly selected, prepared, and analyzed, samples from onions were used to assess whether contaminants such as heavy metals were present using atomic absorption spectroscopy. The mean readings for chromium, copper, lead, and zinc in the native and imported onion samples ranged from 0.00 to 6.24., 4.78 to 21.61, 0.00 to 37.00, 31.75 to 70.16 mg kg-1, and from 0.00 to 17.93, 3.64 to 17.04, 0.00 to 26.00, 10.97 to 42.72 mg kg-1, respectively. For the majority of the samples of foreign onions, the ADI values of Pb were higher than the PMTDI. Most onion samples had Hazard Index values higher than 1, indicating a risk in the future to human health (carcinogenic) from these onions intake.
本研究从孟加拉国达卡的批发市场收集了国产洋葱和进口洋葱样本,并对其重金属浓度进行了测量。据估计,食用洋葱可能会引发多种健康问题。在对洋葱样本进行随机抽取、制备和分析后,使用原子吸收光谱法评估其中是否含有重金属等污染物。本地洋葱和进口洋葱样本中铬、铜、铅和锌的平均读数分别为 0.00 至 6.24、4.78 至 21.61、0.00 至 37.00、31.75 至 70.16 毫克/千克-1,以及 0.00 至 17.93、3.64 至 17.04、0.00 至 26.00、10.97 至 42.72 毫克/千克-1。大多数洋葱样品中,铅的每日允许摄入量值都高于 PMTDI 值。大部分洋葱样本的危害指数高于 1,显示摄入这些洋葱会对人体健康构成风险(致癌)。
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引用次数: 0
A Case Report of Coenurus Cerebralis in a Goat at Dembecha District of Amhara Region, Ethiopia 埃塞俄比亚阿姆哈拉地区登贝查县山羊脑同形虫病例报告
Pub Date : 2023-07-19 DOI: 10.23880/oajmb-16000272
Umer Aa
This outbreak case with an unidentified etiological agent on caprine mortality was reported from Amhara Regional State, West Gojam zone, Dembecha district in February 2023 with the objective of investigating and determining the cause of the caprine death. During a clinical examination, the goat displayed seizures, lateral recumbency, and appetite loss. Additionally, paddling, convulsions, and unconsciousness were observed, which signs of a central nervous system disease. The case for coenurosis cerebralis has been established based on the clinical signs and the presence of certain hosts in the area. The brain was examined postmortem in order to confirm the diagnosis further. Cysts were found during necropsy in the left hemisphere's occipital lobe. The cysts were filled with a clear fluid, and the inner layer of the cysts had several clusters of scolice growing out of it. Larval form of Taenia multiceps, known as Coenurus cerebralis, is found in the small intestines of dogs and other carnivores in the wild. Worldwide, coenurosis is endemic, and it is particularly prevalent in Ethiopia's highlands, where there are many sheep. Commonly occurs in the life cycle of dogs and small ruminants. The larvae of this parasite are found in the brain and spinal cord of intermediate hosts, while the adult stage of the parasite lives in the small intestine of dogs, foxes, coyotes, and jackals. The definitive host becomes infected when it eats the brain or tissue become infected when the dog eats the brain containing the Coenurus cyst, which then develops into Taenia multiceps and begins to pass proglottids containing eggs on pasture. If a person accidentally consumes a parasite egg, they become infected with coenurosis. The primary method of controlling coenurosis is the regular administration of canine anthelmintics and the proper disposal of sheep and goat brain.
2023 年 2 月,阿姆哈拉地区邦西戈贾姆区登贝查地区报告了这起疫情,其病原体不明,导致山羊死亡,目的是调查和确定山羊死亡的原因。在临床检查中,山羊表现出抽搐、侧卧和食欲不振。此外,还观察到划水、抽搐和昏迷等中枢神经系统疾病的症状。根据临床症状和该区域某些宿主的存在,脑并发症的病例已经确定。为了进一步确诊,对大脑进行了尸检。尸检时在左半球枕叶发现了囊肿。囊肿内充满了透明液体,囊肿内层长出了几簇瘰疬。多疟原虫的幼虫被称为脑蜗牛,存在于野生狗和其他食肉动物的小肠中。在世界范围内,脑蜗牛症是一种地方病,在绵羊众多的埃塞俄比亚高原地区尤为流行。常见于狗和小型反刍动物的生命周期中。这种寄生虫的幼虫寄生在中间宿主的大脑和脊髓中,成虫寄生在狗、狐狸、郊狼和豺的小肠中。当狗吃了含有鞘氨醇囊肿的大脑或组织时,确定宿主就会受到感染,然后鞘氨醇囊肿就会发育成多喙洮螨,并开始在牧场上排出含有虫卵的原虫。如果人不小心吃了寄生虫卵,就会感染蟠尾丝虫病。控制同源寄生虫病的主要方法是定期服用犬用抗蠕虫药,并妥善处理绵羊和山羊的大脑。
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引用次数: 0
Assessment of the Nutritional and Infectious Status of Vulnerable Children Consulted at Beyla Hospital, Guinea 评估几内亚贝拉医院就诊的弱势儿童的营养和感染状况
Pub Date : 2023-07-19 DOI: 10.23880/oajmb-16000269
Sangare M
Introduction: Acute malnutrition is a primary health concern among vulnerable children. The objective of this work is to know the nutritional status of the 321 children of these vulnerable children and to assess their infectious states. Methodology: Smart nutritional survey according to a list drawn up by the community services of the Town Hall. Follow-up of a biological analysis of the stools with the Polymerase Chain Reaction to detect the germ involved. Statistical processing with Smart software. Results: Rate of acute malnutrition in Z-scores: Prevalence of global acute malnutrition of: (29) 9.03%. With: (17) 5.29% moderate and (12) 3.73% severe. Rate of acute malnutrition as a percentage of the median. Prevalence of global acute malnutrition: (12) 3.73% with (8) 2.49% moderate and (4) 1.24% severe plus edema. Chronic malnutrition rate in Z-scores. Prevalence of global chronic malnutrition: (91) 28.34%. Shigella sonnei DNA alone was found in 20 (6.2%) children. Malnutrition-shigellosis copathology was found in 120 (37.4%) of these children. A total of 140 (43.6%) cases of Shigella sonnei DNA detected (P = 1.4). Conclusion: Among the 321 vulnerable children, malnutrition was a reality against the backdrop of bloody Shigella sonnei dysentery. Contracted during the various gatherings.
引言急性营养不良是弱势儿童的主要健康问题。这项工作的目的是了解 321 名弱势儿童的营养状况,并评估他们的感染状态。调查方法根据市政厅社区服务部门拟定的名单进行智能营养调查。通过聚合酶链式反应对粪便进行生物分析,以检测相关病菌。使用 Smart 软件进行统计处理。结果急性营养不良率的 Z 值:全球急性营养不良患病率为:(29)9.03%:(29) 9.03%.其中:(17)中度占 5.29%,(12)重度占 3.73%。急性营养不良率占中位数的百分比。总体急性营养不良率:(12)3.73%,其中(8)2.49%为中度,(4)1.24%为重度加水肿。以 Z 值表示的慢性营养不良率。总体慢性营养不良率:(91)28.34%。在 20 名(6.2%)儿童中仅发现了子内志贺氏杆菌 DNA。这些儿童中有 120 人(37.4%)发现了营养不良-志贺氏菌病共同病理现象。共检测到 140 例(43.6%)儿子志贺氏菌 DNA(P = 1.4)。结论在 321 名弱势儿童中,营养不良是在血性子内志贺氏菌痢疾的背景下发生的。在各种聚会期间感染。
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引用次数: 0
Burden of Infectious Diseases in North East India: A Mini-Review 印度东北部的传染病负担:小型回顾
Pub Date : 2023-07-19 DOI: 10.23880/oajmb-16000270
Jakharia A
North East India, with its unique geographical and cultural characteristics, bears a significant burden of infectious diseases. This mini review provides an overview of the prevalent infectious diseases in the region, highlighting the highest disease burden and the most endemic diseases. Malaria emerges as a major public health concern, with frequent outbreaks and substantial morbidity and mortality. Dengue fever, tuberculosis, Japanese encephalitis, Chikungunya, rickettsia diseases, waterborne enteric infections, hepatitis, and HIV/AIDS are also prevalent in the region. Challenges such as rugged terrain, limited transportation infrastructure, limited healthcare infrastructure, inadequate diagnostics, socio-economic factors and sharing of international border with four neighboring countries etc hinder disease control efforts. Strengthening vector control, improving diagnostics, expanding healthcare access, and raising community awareness are crucial strategies for reducing the burden of infectious diseases. Surveillance and research efforts are needed to enhance understanding and control of these diseases. Febrile illness like Scrub typhus stands out as the most endemic disease in the hilly regions, characterized by high prevalence, associated morbidity and mortality, and a lack of knowledge about its epidemiology and impact. Active surveillance is crucial to better understand the burden and distribution of the disease and address the challenges in the region.
印度东北部具有独特的地理和文化特征,承受着巨大的传染病负担。这篇微型综述概述了该地区流行的传染病,重点介绍了疾病负担最重和最流行的疾病。疟疾是主要的公共卫生问题,经常爆发,发病率和死亡率都很高。登革热、肺结核、日本脑炎、基孔肯雅病、立克次体病、水传播肠道传染病、肝炎和艾滋病毒/艾滋病也在该地区流行。崎岖的地形、有限的交通基础设施、有限的医疗保健基础设施、诊断手段不足、社会经济因素以及与四个邻国接壤等挑战阻碍了疾病控制工作。加强病媒控制、改善诊断、扩大医疗服务范围以及提高社区意识是减轻传染病负担的重要战略。需要开展监测和研究工作,以加强对这些疾病的了解和控制。恙虫病等发热性疾病是丘陵地区最常见的地方病,其特点是流行率高、相关发病率和死亡率高,但对其流行病学和影响却缺乏了解。积极监测对于更好地了解该疾病的负担和分布情况以及应对该地区的挑战至关重要。
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引用次数: 0
Assessing the Human Health Risk from Heavy MetalContaminated Vegetables Grown Close to the Tannery Industrial Area Using the Hazard Index (HI) and Hazard Quotient (HQ) 利用危害指数(HI)和危害商数(HQ)评估制革工业区附近种植的受重金属污染的蔬菜对人类健康造成的风险
Pub Date : 2023-07-19 DOI: 10.23880/oajmb-16000274
Chamon As
To assess the contamination load in vegetables and its possible human health hazards, heavy metals concentration (Cr, Cd, Cu, Pb, Ni, and Zn) in vegetables grown in the vicinity of the studied tannery area were determined. Health risk due to the consumption of vegetables was calculated from the metal concentration of the studied vegetables and the study signifies more potential to cause health hazard (cancer) (Hazard Index>1). The present study indicated that concentrations of Cr in the vegetable species were within the range of 7.5-9.75, 5.38-10.14, 25.5-28.5 and 2.65 mg kg-1 of dry weight (DW), in bottle gourd fruit, bottle gourd shoot, kalmi shoot, and red amaranth, which was above the MPL (1-2 mg/kg). The findings revealed that the mean concentration of the studied heavy metals (Cr, Cd, Pb, Ni, Cu, Zn,) exceeded the MPL in most of the measured vegetables because of higher translocation from the source to edible parts. For the majority of the samples, the ADI values of Cr and Pb were higher than the PMTDI. Open dumping of tannery wastes and effluents, and tanning activities involve serious environmental hazards. Adequate preventive measures should be taken in tannery industrial activities with a view to ensuring a safe, sound, and healthy environment for the greater benefit of Bangladesh.
为了评估蔬菜中的污染负荷及其可能对人类健康造成的危害,我们测定了所研究的制革区附近种植的蔬菜中的重金属浓度(铬、镉、铜、铅、镍和锌)。根据所研究蔬菜的金属浓度计算出食用蔬菜的健康风险,研究结果表明,食用蔬菜更有可能导致健康危害(癌症)(危害指数>1)。本研究表明,匏瓜果、匏瓜嫩芽、卡米嫩芽和红苋菜中的铬浓度范围分别为 7.5-9.75、5.38-10.14、25.5-28.5 和 2.65 毫克/千克干重(DW),高于 MPL(1-2 毫克/千克)。研究结果表明,由于重金属(铬、镉、铅、镍、铜、锌)从源头到食用部位的迁移率较高,因此大多数被测蔬菜中的重金属平均浓度都超过了最大允许浓度。在大多数样本中,铬和铅的每日允许摄入量都高于 PMTDI 值。露天倾倒制革废料和污水以及制革活动会对环境造成严重危害。应在制革工业活动中采取适当的预防措施,以确保安全、良好和健康的环境,为孟加拉国带来更大的利益。
{"title":"Assessing the Human Health Risk from Heavy MetalContaminated Vegetables Grown Close to the Tannery Industrial Area Using the Hazard Index (HI) and Hazard Quotient (HQ)","authors":"Chamon As","doi":"10.23880/oajmb-16000274","DOIUrl":"https://doi.org/10.23880/oajmb-16000274","url":null,"abstract":"To assess the contamination load in vegetables and its possible human health hazards, heavy metals concentration (Cr, Cd, Cu, Pb, Ni, and Zn) in vegetables grown in the vicinity of the studied tannery area were determined. Health risk due to the consumption of vegetables was calculated from the metal concentration of the studied vegetables and the study signifies more potential to cause health hazard (cancer) (Hazard Index>1). The present study indicated that concentrations of Cr in the vegetable species were within the range of 7.5-9.75, 5.38-10.14, 25.5-28.5 and 2.65 mg kg-1 of dry weight (DW), in bottle gourd fruit, bottle gourd shoot, kalmi shoot, and red amaranth, which was above the MPL (1-2 mg/kg). The findings revealed that the mean concentration of the studied heavy metals (Cr, Cd, Pb, Ni, Cu, Zn,) exceeded the MPL in most of the measured vegetables because of higher translocation from the source to edible parts. For the majority of the samples, the ADI values of Cr and Pb were higher than the PMTDI. Open dumping of tannery wastes and effluents, and tanning activities involve serious environmental hazards. Adequate preventive measures should be taken in tannery industrial activities with a view to ensuring a safe, sound, and healthy environment for the greater benefit of Bangladesh.","PeriodicalId":257510,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139357569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection Methods of Genetically Modified Organisms (GMOS): Review 转基因生物检测方法综述
Pub Date : 2023-04-05 DOI: 10.23880/oajmb-16000265
Gidi M
A living organism is considered a genetically modified organism (GMO) when a new foreign DNA segment or transgene is inserted into it to create a new trait. The field of biotechnology is currently developing at a rapid pace, with more traits and applications emerging every day. Due to concerns about the environment and living organisms, societies have not yet accepted this technology. Countries adhere to a strict biosafety protocol to reduce their fear of this issue and detect DNA and GMO protein molecules using a variety of mechanisms to ensure biotechnology products are free of foreign material or contain it at a level below the threshold, if it is present. Based on the quantity and quality of DNA and protein in these samples, these detections are made. Quantitative detection is crucial for determining the GMO threshold for each sample. The DNA-based detection of GMOs using various PCRs, either qualitatively or quantitatively is one of these detection techniques. The second most popular technique for determining how much a protein is expressed in a side organism is protein-based detection. DNA microarray, biosensors, chromatography, and DNA sequencing can all be used to find GMOs. The availability of accurate and sensitive GMO detection techniques allows us to control the presence of GMOs in crops, foods, and ingredient sources.
当一种新的外来DNA片段或转基因基因被插入其中以产生新的特征时,一种活的有机体被认为是转基因生物(GMO)。生物技术领域正在快速发展,每天都有更多的特性和应用出现。由于对环境和生物的担忧,社会还没有接受这项技术。各国遵守严格的生物安全议定书,以减少他们对这一问题的恐惧,并使用各种机制检测DNA和转基因蛋白分子,以确保生物技术产品不含外来物质,或者如果存在的话,其含量低于阈值。根据这些样品中DNA和蛋白质的数量和质量,进行这些检测。定量检测对于确定每个样品的转基因生物阈值至关重要。利用各种pcr对转基因生物进行基于dna的定性或定量检测就是这些检测技术之一。确定蛋白质在侧生物体中表达多少的第二种最流行的技术是基于蛋白质的检测。DNA微阵列、生物传感器、色谱和DNA测序都可以用来寻找转基因生物。准确灵敏的转基因生物检测技术使我们能够控制作物、食品和成分来源中转基因生物的存在。
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引用次数: 0
Advances in Genomics: Crops Adapting to Climate Change 基因组学进展:作物适应气候变化
Pub Date : 2023-04-05 DOI: 10.23880/oajmb-16000264
Gidi M
In a world where food consumption is rising, climate change poses a severe danger to feeding a growing population. Previously, increased agricultural output was achieved by using fertilizer and insecticides for improved weed and pest control. However, these techniques rely on exhaustible resources and are frequently unstable. Current developments in advanced genetics are paving the door for long-term agricultural intensification and greater global warming crop adaptability. The amount of quality genomic information accessible has been rapidly increasing as a result of the widespread usage of genome sequencing technology. The increasing availability of genomic data has facilitated the shift to plant pan-genomics, allowing researchers to easily know the diversity and available traits for crop improvement and cultivar development. These advancements enhance genomic-assisted breeding, which allows for the quick engagement of candidate genes in climatic conditions and agricultural characteristics, enabling the development of resilient crops.
在一个粮食消费量不断上升的世界,气候变化对养活不断增长的人口构成了严重威胁。以前,农业产量的增加是通过使用化肥和杀虫剂来改善杂草和害虫控制来实现的。然而,这些技术依赖于可耗尽的资源,而且往往不稳定。目前先进遗传学的发展为长期农业集约化和更强的全球变暖作物适应性铺平了道路。由于基因组测序技术的广泛使用,可获得的高质量基因组信息的数量正在迅速增加。基因组数据的不断增加促进了向植物泛基因组学的转变,使研究人员能够轻松地了解作物的多样性和可用性状,以进行作物改良和品种开发。这些进步加强了基因组辅助育种,使候选基因能够在气候条件和农业特征中快速发挥作用,从而能够培育出抗逆性强的作物。
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引用次数: 0
Applications of Genomic Selection in Animal Breeding; Challenges and Opportunities 基因组选择在动物育种中的应用挑战与机遇
Pub Date : 2023-04-04 DOI: 10.23880/oajmb-16000263
Borawake Sk
The world's population demand and animal output are significantly out of balance. Although traditional breeding techniques have been successful in selecting animal populations for a variety of traits with economic significance, the reliability of breeding value has always been in doubt. According to simulation and experiment data, genomic selection for young animals without own performance can predict breeding values with good accuracy. Genetic markers that cover the entire genome are employed in genomic selection, a sort of marker-assisted selection, to ensure that all loci for quantitative traits are in linkage disequilibrium with at least one marker. Early animal selection enables the development of innovative breeding techniques that increase genetic advancement while decreasing costs. The future of animal breeding companies lies in genomic selection, which increases genetic gain by reducing genetic interval and enhancing reliability. To regulate long-term genetic gain and increase the precision of genomic estimated value, more study is needed. An overview of the developments in genomic selection and its use in animal breeding was the goal of this paper.
世界人口需求和动物产出严重失衡。尽管传统育种技术在选择具有经济意义的多种性状的动物种群方面取得了成功,但育种价值的可靠性一直受到质疑。模拟和实验数据表明,对没有自身生产性能的幼畜进行基因组选择,可以较准确地预测育种值。覆盖整个基因组的遗传标记被用于基因组选择,这是一种标记辅助选择,以确保数量性状的所有位点与至少一个标记处于连锁不平衡状态。早期动物选择使创新育种技术的发展能够在降低成本的同时增加遗传进步。动物育种公司的未来在于基因组选择,即通过缩短遗传间隔和提高可靠性来增加遗传收益。为了调控长期遗传增益,提高基因组估计值的精度,还需要进行更多的研究。概述了基因组选择的发展及其在动物育种中的应用。
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引用次数: 0
Bioleaching - Eco-Friendly Approach for Management of Electronic Waste 生物淋滤-环保的电子废物处理方法
Pub Date : 2023-04-04 DOI: 10.23880/oajmb-16000259
G. A
The different types of wastes viz., food, electronic, household, medical, etc. accumulate in large amount. The electronic waste is a serious problem which needs an urgent solution. The chemical process has disadvantages which is costly and causes soil and water pollution. Bioleaching using the microorganisms is a two-step process which can be used for the management of electronic wastes. The bioleaching is economical, eco-friendly and easy process in this. Bioleaching which is a biological process is very important. It is a sustainable approach. The metals leached during bioleaching can be used for making of precious jewellery and ornaments.
不同类型的废物,如食品、电子、家居、医疗等,大量积累。电子垃圾是一个亟待解决的严重问题。化学工艺的缺点是成本高,造成土壤和水污染。利用微生物进行生物浸出是一个两步过程,可用于电子废物的管理。生物浸出是一种经济、环保、简便的工艺。生物浸出是一种非常重要的生物过程。这是一种可持续的方法。生物浸出的金属可用于制作贵重首饰和饰品。
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引用次数: 0
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Open Access Journal of Microbiology & Biotechnology
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