Yunus Başar, F. Gül, M. S. Nas, M. Alma, M. H. Calimli
In this study, slow pyrolysis of oak woods was carried out in a fixed bed tube reactor at four different temperatures ranging from 100 °C to 400 °C and at 5 °C/min speed time intervals. The compositions of the produced bio-tar and bio-oils were determined in detail using FT-IR, GC-MS, HPLC, and NMR devices. Several pyrolysis parameters were carried out to reveal the distribution of pyrolytic products under different pyrolysis temperatures (100–400 °C) and times (1–4 h). During the slow pyrolysis process, oak wood started to decompose to form organic volatile products at a set temperature of 100 °C and reached a maximum yield of volatile products at around 400 °C. GC-MS analyses revealed that different valuable components such as furans, phenolic compounds, carbonyls, linear, aromatic compounds, acids, and hydrocarbons have been formed. Based on the experimental results of the pyrolysis, it has been detected that the temperature and time interval are very effective parameters in the conversion of oak wood to the amount of liquid product.
{"title":"Investigation of value-added compounds derived from oak wood using hydrothermal processing techniques and comprehensive analytical approaches (HPLC, GC-MS, FT-IR, and NMR)","authors":"Yunus Başar, F. Gül, M. S. Nas, M. Alma, M. H. Calimli","doi":"10.32571/ijct.1365592","DOIUrl":"https://doi.org/10.32571/ijct.1365592","url":null,"abstract":"In this study, slow pyrolysis of oak woods was carried out in a fixed bed tube reactor at four different temperatures ranging from 100 °C to 400 °C and at 5 °C/min speed time intervals. The compositions of the produced bio-tar and bio-oils were determined in detail using FT-IR, GC-MS, HPLC, and NMR devices. Several pyrolysis parameters were carried out to reveal the distribution of pyrolytic products under different pyrolysis temperatures (100–400 °C) and times (1–4 h). During the slow pyrolysis process, oak wood started to decompose to form organic volatile products at a set temperature of 100 °C and reached a maximum yield of volatile products at around 400 °C. GC-MS analyses revealed that different valuable components such as furans, phenolic compounds, carbonyls, linear, aromatic compounds, acids, and hydrocarbons have been formed. Based on the experimental results of the pyrolysis, it has been detected that the temperature and time interval are very effective parameters in the conversion of oak wood to the amount of liquid product.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"94 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139195654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rheum ribes L. belongs to the family Polygonaceae and is locally known as "ışkın, ucgun, highland banana". In this study, ultrasound-assisted extraction with a solvent mixture of methanol: ethyl acetate was used to isolate the volatiles of the plant from the root, stem, and leaf organs. The essential oils were extracted from the plant roots by water distillation to determine the essential oil content and composition. GC-MS (Gas Chromatography-Mass Spectrometry) was used to analyse the content of essential oils and extracts. Carvacrol (40.41%) and gamma-terpinene (%22.90) were used in the root extracts of the plant., 2,4-ditert-butylphenol (20.76%) and carvacrol (13.52%) in the stem extracts and 2,4-ditert-butylphenol (25.87%) and methyl formate (6.87%) in the leaf extracts. The volatile components of 6-butyl-3-methoxy-2-cyclohexen-1-one (30.06%) and 3-carene (16.42%) were found in the essential oil. When the structure of the volatile components in both the extract and the essential oil of the plant is examined, the presence of versatile volatile components that can be used in the production of pharmacological, bioactive, flavouring, dye material, and perfume indicated that the plant can be used as an important medicinal and aromatic plant source.
{"title":"Analysis of Essential Oil and Volatile Components of Different Organs of Isgin (Rheum ribes L.) Plant by Ultrasound-Assisted Extraction Method","authors":"Hasan Asi̇l, M. Köroğlu","doi":"10.32571/ijct.1326549","DOIUrl":"https://doi.org/10.32571/ijct.1326549","url":null,"abstract":"Rheum ribes L. belongs to the family Polygonaceae and is locally known as \"ışkın, ucgun, highland banana\". In this study, ultrasound-assisted extraction with a solvent mixture of methanol: ethyl acetate was used to isolate the volatiles of the plant from the root, stem, and leaf organs. The essential oils were extracted from the plant roots by water distillation to determine the essential oil content and composition. GC-MS (Gas Chromatography-Mass Spectrometry) was used to analyse the content of essential oils and extracts. Carvacrol (40.41%) and gamma-terpinene (%22.90) were used in the root extracts of the plant., 2,4-ditert-butylphenol (20.76%) and carvacrol (13.52%) in the stem extracts and 2,4-ditert-butylphenol (25.87%) and methyl formate (6.87%) in the leaf extracts. The volatile components of 6-butyl-3-methoxy-2-cyclohexen-1-one (30.06%) and 3-carene (16.42%) were found in the essential oil. When the structure of the volatile components in both the extract and the essential oil of the plant is examined, the presence of versatile volatile components that can be used in the production of pharmacological, bioactive, flavouring, dye material, and perfume indicated that the plant can be used as an important medicinal and aromatic plant source.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tülay Gürsoy, M. Alma, Ertuğrul Altuntaş, E. Karaogul
Polyurethanes (PUs) are polymers obtained by reacting diisocyanates with a group of polyols. The first synthesized PU compounds were prepared using petroleum subproduct compounds. In this research study, biomass-containing polyols, which have been studied by other scientists, were prepared using potato crust and polymerized with diisocyanates to produce PU foam. Polyol reactions were carried out using the microwave heating method. Synthesis reactions and structural properties of polyols have been studied in many aspects. The most available polyol was used for PU synthesis. Different formulations were tried for PU synthesis and as a result, PU foam containing nearly 25% starch-polyol was synthesized. The chemical structure of PU polymer was identified by ATR-FTIR spectroscopy and crystallographic properties by WA-XRD analysis. The physical and mechanical properties of PU foam, which is used as a large number of building and construction materials, including thermal insulation materials, were evaluated by comparing them with a commercial PU foam. According to the results of our research, it was detected that the incorporation of biomass into the structure of PU polymer improved its density, heat conduction coefficient, pressure based mechanical properties. PU foam derived from potato waste has a WA XRD-ray diffraction peak between 13.1-28.5o. This data is between 12.5-23o in synthetic commercial foam and has been positively improved in the product we synthesized as a result of combining biomass into the structure. The synthesized biomass-based PU foam can be used as thermal insulation material. Biomass-based PU foam has been synthesized with features that can be used as a thermal insulation material.
{"title":"Preparation and Characterization of Potato Crust-Based Polyurethane Foam-I","authors":"Tülay Gürsoy, M. Alma, Ertuğrul Altuntaş, E. Karaogul","doi":"10.32571/ijct.1368742","DOIUrl":"https://doi.org/10.32571/ijct.1368742","url":null,"abstract":"Polyurethanes (PUs) are polymers obtained by reacting diisocyanates with a group of polyols. The first synthesized PU compounds were prepared using petroleum subproduct compounds. In this research study, biomass-containing polyols, which have been studied by other scientists, were prepared using potato crust and polymerized with diisocyanates to produce PU foam. Polyol reactions were carried out using the microwave heating method. Synthesis reactions and structural properties of polyols have been studied in many aspects. The most available polyol was used for PU synthesis. Different formulations were tried for PU synthesis and as a result, PU foam containing nearly 25% starch-polyol was synthesized. The chemical structure of PU polymer was identified by ATR-FTIR spectroscopy and crystallographic properties by WA-XRD analysis. The physical and mechanical properties of PU foam, which is used as a large number of building and construction materials, including thermal insulation materials, were evaluated by comparing them with a commercial PU foam. According to the results of our research, it was detected that the incorporation of biomass into the structure of PU polymer improved its density, heat conduction coefficient, pressure based mechanical properties. PU foam derived from potato waste has a WA XRD-ray diffraction peak between 13.1-28.5o. This data is between 12.5-23o in synthetic commercial foam and has been positively improved in the product we synthesized as a result of combining biomass into the structure. The synthesized biomass-based PU foam can be used as thermal insulation material. Biomass-based PU foam has been synthesized with features that can be used as a thermal insulation material.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139217421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tülay Gürsoy, M. Alma, Ertuğrul Altuntaş, E. Karaogul
In this research study, environmentally friendly and biodegradable PU polymer foam was synthesized from starch-containing potato crust to be used as a thermal insulation material by reducing reliance on fossil resources and utilizing biomass resources. Biopolyols were obtained by reacting with active solvents at different reaction times, in the presence of different catalysts and at different catalyst concentrations. The most suitable polyol in terms of biomass content, density, viscosity and acid-hydroxyl number was selected for PU foam synthesis. Reactions for PU synthesis were tried and PU foam was synthesized. The synthesized PU foam was examined by Scanning Electron Microscope (SEM) and Thermo Gravimetric Analysis (TGA). Its morphological structure, thermal degradation properties, sound transmission coefficient and water absorption properties were determined by comparing it with a commercial PU foam. SEM images showed a heterogeneous pore distribution with closed and open cells, the majority of which were closed. From the TGA results, it was determined that a two-step degradation occurred and incorporating biomass into its structure improved the total thermal degradation properties. The sound transmission rate of starch-containing PU foam, when used as a thermal insulation material, was measured to be lower than the concrete structure, but partially close to and higher than that of commercial PU foam. The water absorption properties of the synthesized PU foam were found to be significantly higher compared to commercial PU foam and and contributed to its usability as a thermal insulation material. Thermal insulation material PU foam is synthesized in terms of its properties.
{"title":"Preparation and Characterization of Potato Crust-Based Polyurethane Foam-II","authors":"Tülay Gürsoy, M. Alma, Ertuğrul Altuntaş, E. Karaogul","doi":"10.32571/ijct.1368730","DOIUrl":"https://doi.org/10.32571/ijct.1368730","url":null,"abstract":"In this research study, environmentally friendly and biodegradable PU polymer foam was synthesized from starch-containing potato crust to be used as a thermal insulation material by reducing reliance on fossil resources and utilizing biomass resources. Biopolyols were obtained by reacting with active solvents at different reaction times, in the presence of different catalysts and at different catalyst concentrations. The most suitable polyol in terms of biomass content, density, viscosity and acid-hydroxyl number was selected for PU foam synthesis. Reactions for PU synthesis were tried and PU foam was synthesized. The synthesized PU foam was examined by Scanning Electron Microscope (SEM) and Thermo Gravimetric Analysis (TGA). Its morphological structure, thermal degradation properties, sound transmission coefficient and water absorption properties were determined by comparing it with a commercial PU foam. SEM images showed a heterogeneous pore distribution with closed and open cells, the majority of which were closed. From the TGA results, it was determined that a two-step degradation occurred and incorporating biomass into its structure improved the total thermal degradation properties. The sound transmission rate of starch-containing PU foam, when used as a thermal insulation material, was measured to be lower than the concrete structure, but partially close to and higher than that of commercial PU foam. The water absorption properties of the synthesized PU foam were found to be significantly higher compared to commercial PU foam and and contributed to its usability as a thermal insulation material. Thermal insulation material PU foam is synthesized in terms of its properties.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"49 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thin film preparation and coatings technology has been gaining attention as there is an increasing demand to the functionalized novel materials. Surface design through catalytically active materials such as metal oxides or zeolites as thin films and application through coating provides unique properties to the substance and result novel materials physically and chemically differing from their bulk form. Design technologies allow the preparation of structurally ordered thin films and coatings. Currently, designed thin film materials and coatings have a wide application range such as catalysis, sensing, anti- reflective surfaces, photovoltaics, or specialty design for targeted applications. This study provides a brief overview to the preparation methods of catalytically active coatings and thin film substances, which might be of industrial relevance in the case of the design for targeted applications.
{"title":"An overview to current trends in metal oxide thin film preparation methods","authors":"Cemre Avşar","doi":"10.32571/ijct.1327047","DOIUrl":"https://doi.org/10.32571/ijct.1327047","url":null,"abstract":"Thin film preparation and coatings technology has been gaining attention as there is an increasing demand to the functionalized novel materials. Surface design through catalytically active materials such as metal oxides or zeolites as thin films and application through coating provides unique properties to the substance and result novel materials physically and chemically differing from their bulk form. Design technologies allow the preparation of structurally ordered thin films and coatings. Currently, designed thin film materials and coatings have a wide application range such as catalysis, sensing, anti- reflective surfaces, photovoltaics, or specialty design for targeted applications. This study provides a brief overview to the preparation methods of catalytically active coatings and thin film substances, which might be of industrial relevance in the case of the design for targeted applications.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"227 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139251138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obstructive sleep apnea (OSA) is a common breathing disorder characterized by repeated obstruction of the upper airway during sleep. Although polysomnography (PSG) is the widely used method for the diagnosis of OSA, it is a time-consuming and expensive method. Because it requires at least 1 night stay in the hospital and technical personnel are needed. Therefore, it has been focused on biomarkers that can be easily detected in blood for the diagnosis of OSA. Some studies have highlighted the relationship between OSA and cancer in humans, and HIF-1 is an important regulator in this process. KDM3A is a histone demethylase that increases hypoxic gene expression. We aimed to evaluate whether the expression levels of HIF-1α and KDM3A genes could be useful predictors in patients with OSA. Our study included 50 patients with OSA and 50 healthy controls. qRT-PCR was used to detect mRNA levels of HIF-1α, KDM3A, and epithelial-mesenchymal transition (EMT) genes in the leukocyte samples. The expression level of the HIF-1α gene was found significantly higher in the OSA group compared to the controls, and no statistically significant difference was detected in the expression levels of the KDM3A and EMT genes.
阻塞性睡眠呼吸暂停（OSA）是一种常见的呼吸障碍，其特点是睡眠时上气道反复阻塞。虽然多导睡眠图（PSG）是目前广泛使用的诊断 OSA 的方法，但它是一种耗时且昂贵的方法。因为它至少需要在医院住一晚，而且需要技术人员。因此，人们将注意力集中在容易在血液中检测到的生物标志物上，以诊断 OSA。一些研究强调了 OSA 与人类癌症之间的关系，而 HIF-1 是这一过程中的重要调节因子。KDM3A 是一种组蛋白去甲基化酶，可增加缺氧基因的表达。我们的目的是评估 HIF-1α 和 KDM3A 基因的表达水平是否可以作为 OSA 患者的有用预测指标。研究采用 qRT-PCR 技术检测白细胞样本中 HIF-1α、KDM3A 和上皮-间质转化（EMT）基因的 mRNA 水平。结果发现，与对照组相比，OSA 组 HIF-1α 基因的表达水平明显升高，而 KDM3A 和 EMT 基因的表达水平则无统计学差异。
{"title":"HIF-1α: A POTENTIAL BIOMARKER IN OBSTRUCTIVE SLEEP APNEA","authors":"Derya Polat, Elif Pala, Filiz Gerçeker","doi":"10.32571/ijct.1325830","DOIUrl":"https://doi.org/10.32571/ijct.1325830","url":null,"abstract":"Obstructive sleep apnea (OSA) is a common breathing disorder characterized by repeated obstruction of the upper airway during sleep. Although polysomnography (PSG) is the widely used method for the diagnosis of OSA, it is a time-consuming and expensive method. Because it requires at least 1 night stay in the hospital and technical personnel are needed. Therefore, it has been focused on biomarkers that can be easily detected in blood for the diagnosis of OSA. Some studies have highlighted the relationship between OSA and cancer in humans, and HIF-1 is an important regulator in this process. KDM3A is a histone demethylase that increases hypoxic gene expression. We aimed to evaluate whether the expression levels of HIF-1α and KDM3A genes could be useful predictors in patients with OSA. Our study included 50 patients with OSA and 50 healthy controls. qRT-PCR was used to detect mRNA levels of HIF-1α, KDM3A, and epithelial-mesenchymal transition (EMT) genes in the leukocyte samples. The expression level of the HIF-1α gene was found significantly higher in the OSA group compared to the controls, and no statistically significant difference was detected in the expression levels of the KDM3A and EMT genes.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139254019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to determine the phenolic compound contents of Nasturtium officinale (N. officinale) extracts prepared with water, methanol, ethanol, and chloroform, as well as extracts prepared by evaporation and lyophilization, and parts of N. officinale by LC-MS/MS (Liquid Chromatography-Mass spectrometry/Mass spectrometry). The results obtained not only contribute to knowledge about the benefits of N. officinale but also show the effect of different solvents and different extraction methods on the determination of phenolic compounds. In addition to these results, the importance of the cold chain in the determination of some phenolic compounds has also been demonstrated. While it is observed that the number of phenolic components obtained from the extracts prepared with methanol and ethanol is high; It is observed that some phenolic compounds such as quinic acid, fumaric acid, aconitic acid, and p-coumaric acid dissolve very well in water and temperature is important.
{"title":"Determination of Phenolic Compounds in Nasturtium Officinale by LC-MS / MS Using Different Extraction Methods and Different Solvents","authors":"Leyla Ercan, Mehmet Doğru","doi":"10.32571/ijct.1150482","DOIUrl":"https://doi.org/10.32571/ijct.1150482","url":null,"abstract":"This study aimed to determine the phenolic compound contents of Nasturtium officinale (N. officinale) extracts prepared with water, methanol, ethanol, and chloroform, as well as extracts prepared by evaporation and lyophilization, and parts of N. officinale by LC-MS/MS (Liquid Chromatography-Mass spectrometry/Mass spectrometry). The results obtained not only contribute to knowledge about the benefits of N. officinale but also show the effect of different solvents and different extraction methods on the determination of phenolic compounds. In addition to these results, the importance of the cold chain in the determination of some phenolic compounds has also been demonstrated. While it is observed that the number of phenolic components obtained from the extracts prepared with methanol and ethanol is high; It is observed that some phenolic compounds such as quinic acid, fumaric acid, aconitic acid, and p-coumaric acid dissolve very well in water and temperature is important.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"2010 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139277057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Kahraman, Ahmet Oral Sarıoğlu, Semih Güler, Mehmet Sönmez
In this study, we aimed to investigate the apoptotic effects of the lanthanide complex TBK-23, which was used in biological imaging due to its magnetic and spectroscopic properties. The study utilized HTB-54 and BEAS-2B cell lines. The cells were subjected to TBK-23 and cisplatin at active doses for a duration of 24 hours. Subsequently, flow cytometry was employed to assess the quantity of apoptotic cells, while quantitative RT-PCR was used to measure the expression levels of BAX, BCL-2, and BCL-xL. While cisplatin at 31 µM increased the proapoptotic BAX expression level in HTB-54 and BEAS-2B cells, TBK-23 increased BAX in cancer cells at the same concentration, but there was no observable effect in healthy cells. TBK-23 was found to have higher inhibitory effect on the expression of the antiapoptotic BCL-2 gene in cancer cells compared to that of cisplatin-treated cells. Consequently, it was determined that TBK-23, a novel metal-based compound, exhibited apoptotic effects similar to that of cisplatin and could be a potential chemotherapeutic agent.
{"title":"Determination of Apoptotic Effects of Newly Synthesized Avobenzone Sm(III) Complex in Non-Small Cell Lung Cancer","authors":"D. Kahraman, Ahmet Oral Sarıoğlu, Semih Güler, Mehmet Sönmez","doi":"10.32571/ijct.1321871","DOIUrl":"https://doi.org/10.32571/ijct.1321871","url":null,"abstract":"In this study, we aimed to investigate the apoptotic effects of the lanthanide complex TBK-23, which was used in biological imaging due to its magnetic and spectroscopic properties. The study utilized HTB-54 and BEAS-2B cell lines. The cells were subjected to TBK-23 and cisplatin at active doses for a duration of 24 hours. Subsequently, flow cytometry was employed to assess the quantity of apoptotic cells, while quantitative RT-PCR was used to measure the expression levels of BAX, BCL-2, and BCL-xL. While cisplatin at 31 µM increased the proapoptotic BAX expression level in HTB-54 and BEAS-2B cells, TBK-23 increased BAX in cancer cells at the same concentration, but there was no observable effect in healthy cells. TBK-23 was found to have higher inhibitory effect on the expression of the antiapoptotic BCL-2 gene in cancer cells compared to that of cisplatin-treated cells. Consequently, it was determined that TBK-23, a novel metal-based compound, exhibited apoptotic effects similar to that of cisplatin and could be a potential chemotherapeutic agent.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139321027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurudeen Sanyaolu, Agbola Olufemi̇, Adeola Ibi̇kunle, S. Ogundare, Adejare Oloyede
This study was carried out to evaluate the antifungal activity of Cashew (Anacardium occidentale) nutshell liquid on fungal pathogens of dry rot diseases of yam (Discorea rotundata). The Soxhlet extraction method was used and constituents were identified and quantified using Gas chromatography. Isolation and identification of fungi complexes associated with dry rot disease of yam were made using Potato dextrose agar (PDA) as a medium. The antifungal activity of CNSL was evaluated using the food poisoning technique on PDA at 25, 50, 75 and 100% concentrations of CNSL dissolved in dimethyl sulphoxide. Azulene (57.65%) was the major chemical component of CNSL with phenolic compounds; anacardol, cresols and anacardic acid, among other compounds. CNSL phytochemical screening showed the presence of flavonoids, alkaloids, saponins, tannins, phenols, terpenoids, volatile oil and steroids. Infected yam tubers were isolated, four fungal strains (Fusarium solani, Lasiodiplodia theobromae, Aspergillus fumigatus, and Aspergillus niger) were identified, and pathogenicity test confirmed the association of the fungi species with the dry rot disease of white yam. CNSL was active against the identified fungi and could potentially compete with conventional standard as a suitable fungicide against dry rot disease of white yam
{"title":"CHEMICAL COMPOSITIONS, PHYTOCHEMICAL SCREENINGS AND ANTIFUNGAL ACTIVITIES OF CASHEW NUT SHELL LIQUID EXTRACTS ON PHYTOPATHOGENIC FUNGI OF YAM (Dioscorea rotundata)","authors":"Nurudeen Sanyaolu, Agbola Olufemi̇, Adeola Ibi̇kunle, S. Ogundare, Adejare Oloyede","doi":"10.32571/ijct.1278596","DOIUrl":"https://doi.org/10.32571/ijct.1278596","url":null,"abstract":"This study was carried out to evaluate the antifungal activity of Cashew (Anacardium occidentale) nutshell liquid on fungal pathogens of dry rot diseases of yam (Discorea rotundata). The Soxhlet extraction method was used and constituents were identified and quantified using Gas chromatography. Isolation and identification of fungi complexes associated with dry rot disease of yam were made using Potato dextrose agar (PDA) as a medium. The antifungal activity of CNSL was evaluated using the food poisoning technique on PDA at 25, 50, 75 and 100% concentrations of CNSL dissolved in dimethyl sulphoxide. Azulene (57.65%) was the major chemical component of CNSL with phenolic compounds; anacardol, cresols and anacardic acid, among other compounds. CNSL phytochemical screening showed the presence of flavonoids, alkaloids, saponins, tannins, phenols, terpenoids, volatile oil and steroids. Infected yam tubers were isolated, four fungal strains (Fusarium solani, Lasiodiplodia theobromae, Aspergillus fumigatus, and Aspergillus niger) were identified, and pathogenicity test confirmed the association of the fungi species with the dry rot disease of white yam. CNSL was active against the identified fungi and could potentially compete with conventional standard as a suitable fungicide against dry rot disease of white yam","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"165 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139336173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hawa Bendebane, S. Bendebane, S. Amirat, Rabah Rehamnia
This work aims to improve and characterize a Zn-Ni alloy thin film from a sulfated bath by an electrochemical process. Experimental planning was applied using Minitab 19. For the selection of the best bath composition, a mixture design was applied. It was found that the best bath composition is [boric acid] = 0.1M, [saccharin] = 0.3 g/L, and [2-butene-1,4-diol] = 0.1 g/L. In order to optimize the best experimental conditions to have a better coating an application of the Box-Behnken design has been examined. Temperature, current density, and the ratio [Ni2+]/[Zn2+] are the various parameters. It was found that the best coating in terms of quality, corrosion resistance, brightness, and hardness was obtained under the following conditions: T= 30°C; i= 0.5A/dm2 and [Ni2+]/[Zn2+] = 0.53 with a theoretical response of 312.66 HV and an experimental response of 312.30 HV.These results were confirmed by morphological (SEM) and elemental (EDS) analyses.
{"title":"Planning and processing of Zn-Ni alloy thin film by electrodeposition","authors":"Hawa Bendebane, S. Bendebane, S. Amirat, Rabah Rehamnia","doi":"10.32571/ijct.1230422","DOIUrl":"https://doi.org/10.32571/ijct.1230422","url":null,"abstract":"This work aims to improve and characterize a Zn-Ni alloy thin film from a sulfated bath by an electrochemical process. Experimental planning was applied using Minitab 19. For the selection of the best bath composition, a mixture design was applied. It was found that the best bath composition is [boric acid] = 0.1M, [saccharin] = 0.3 g/L, and [2-butene-1,4-diol] = 0.1 g/L. In order to optimize the best experimental conditions to have a better coating an application of the Box-Behnken design has been examined. Temperature, current density, and the ratio [Ni2+]/[Zn2+] are the various parameters. It was found that the best coating in terms of quality, corrosion resistance, brightness, and hardness was obtained under the following conditions: T= 30°C; i= 0.5A/dm2 and [Ni2+]/[Zn2+] = 0.53 with a theoretical response of 312.66 HV and an experimental response of 312.30 HV.These results were confirmed by morphological (SEM) and elemental (EDS) analyses.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139338915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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