This study reports the findings of fieldwork based on adult fruit fly samples collected from the province of Tokat in the spring and summer months of 2016–2018. Adult fruit fly samples were caught by using insect nets from possible host plants, taken into killing bottles, and then transferred to storage jars. As a result of the diagnostic procedures, a total of 28 fruit fly species belonging to 11 genera of the Tephritidae family were identified. The findings of this study offered significant contributions to the body of knowledge regarding the determination of the fruit fly fauna of Türkiye and the dispersion of fruit flies in our country
{"title":"Fruit fly (Diptera: Tephritidae) fauna in Tokat province (Türkiye)","authors":"Tuğçe İşi̇ni̇, M. Kütük, M. Yaran","doi":"10.32571/ijct.1184571","DOIUrl":"https://doi.org/10.32571/ijct.1184571","url":null,"abstract":"This study reports the findings of fieldwork based on adult fruit fly samples collected from the province of Tokat in the spring and summer months of 2016–2018. Adult fruit fly samples were caught by using insect nets from possible host plants, taken into killing bottles, and then transferred to storage jars. As a result of the diagnostic procedures, a total of 28 fruit fly species belonging to 11 genera of the Tephritidae family were identified. The findings of this study offered significant contributions to the body of knowledge regarding the determination of the fruit fly fauna of Türkiye and the dispersion of fruit flies in our country","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131837132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Using the Gaussian09 software package, N-(6-(2-(dimethylamino)ethoxy)-5-fluoropyridin-3-yl)-2-(4-fluorophenyl)-5-(trifluoromethyl)pyrazolo[1,5 α]pyrimidine-7-amine(DFPA) the theoretically optimal molecular structure, vibration frequencies and related vibrational movements of the molecule were researched. The DFT(B3PW91 and B3LYP) techniques' 6-311G(d,p) basis set was used to perform quantum chemical computations. HOMO and LUMO analysis were performed for charge transfer in the molecule. NBO analysis was used to examine the stability of the molecule as a result of both charge delocalization and hyperconjugative interaction. DFT approach was used to perform MEP and expected infrared sensitivities and Raman activity are also presented. Geometric parameters of both calculated DFT methods are compatible. Binding affinity values and molecular coupling studies show that the title substance forms a stable complex with MtPanK and PanK. It is possible that the molecule has inhibitory activity against MtPanK and PanK, paving the way for new anti-tuberculosis drugs’ the development.
{"title":"HOMO–LUMO, NBO, NLO, MEP analysis and molecular docking using DFT calculations in DFPA molecule","authors":"Mehmet Bağlan, Kenan Gören, Ümit Yildiko","doi":"10.32571/ijct.1135173","DOIUrl":"https://doi.org/10.32571/ijct.1135173","url":null,"abstract":"Using the Gaussian09 software package, N-(6-(2-(dimethylamino)ethoxy)-5-fluoropyridin-3-yl)-2-(4-fluorophenyl)-5-(trifluoromethyl)pyrazolo[1,5 α]pyrimidine-7-amine(DFPA) the theoretically optimal molecular structure, vibration frequencies and related vibrational movements of the molecule were researched. The DFT(B3PW91 and B3LYP) techniques' 6-311G(d,p) basis set was used to perform quantum chemical computations. HOMO and LUMO analysis were performed for charge transfer in the molecule. NBO analysis was used to examine the stability of the molecule as a result of both charge delocalization and hyperconjugative interaction. DFT approach was used to perform MEP and expected infrared sensitivities and Raman activity are also presented. Geometric parameters of both calculated DFT methods are compatible. Binding affinity values and molecular coupling studies show that the title substance forms a stable complex with MtPanK and PanK. It is possible that the molecule has inhibitory activity against MtPanK and PanK, paving the way for new anti-tuberculosis drugs’ the development.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116349252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Bitgen, Özge Göktepe, M. Baran, Eren Kaan İpek, A. Yay
Nonylphenols are endocrine disrupting toxic compounds and are widely used. For this reason, our study aimed to investigate the genotoxic effect of nonylphenols applied at different doses on mouse bone marrow cells. In this study, 5 groups were formed from 50 Wistar albino adult male rats. Groups were classified as control group, the sham administered only (150 µl) group, low dose (25 µl / 125 µl sham), medium dose (50 µl / 100 µl sham) and high dose (75 µl / 75 µl sham) nonylphenol administered group. After 24 hours, the rats were euthanized and analyzed to detect DNA damage by determining the polychromatic erythrocyte/Normochromatic erythrocyte ratio and the number of micronucleated polychromatic erythrocytes in the femur bone marrow cells. While polychromatic erythrocyte/Normochromatic erythrocyte ratio was found to be lower in the groups treated with different doses of nonylphenol, especially in the group treated with high-dose nonylphenol, this decrease was not statistically significant. When the micronucleated polychromatic erythrocyte values were examined, it was observed that there was a statistically significant increase, especially in the medium and high dose groups compared to the control (p=0.0002, p
壬基酚是一种具有内分泌干扰作用的有毒化合物，用途广泛。因此，本研究旨在探讨不同剂量壬基酚对小鼠骨髓细胞的遗传毒性作用。本研究将50只成年雄性Wistar白化大鼠分为5组。各组分为对照组、假手术组(150µl)、低剂量组(25µl / 125µl假手术)、中剂量组(50µl / 100µl假手术)和高剂量组(75µl / 75µl假手术)。24 h后处死大鼠，通过测定股骨骨髓细胞中多染红细胞/正染红细胞比例和微核多染红细胞数量检测DNA损伤。不同剂量壬基酚处理组，尤其是高剂量壬基酚处理组，多染红细胞/正染红细胞比例均较低，但这种下降无统计学意义。当检测微核多染红细胞值时，观察到有统计学意义的增加，特别是在中、高剂量组与对照组相比(p=0.0002, p
{"title":"EVALUATION OF THE GENOTOXIC EFFECT OF NONYLPHENOL APPLIED IN DIFFERENT DOSES ON THE BONE MARROW","authors":"N. Bitgen, Özge Göktepe, M. Baran, Eren Kaan İpek, A. Yay","doi":"10.32571/ijct.1186924","DOIUrl":"https://doi.org/10.32571/ijct.1186924","url":null,"abstract":"Nonylphenols are endocrine disrupting toxic compounds and are widely used. For this reason, our study aimed to investigate the genotoxic effect of nonylphenols applied at different doses on mouse bone marrow cells. In this study, 5 groups were formed from 50 Wistar albino adult male rats. Groups were classified as control group, the sham administered only (150 µl) group, low dose (25 µl / 125 µl sham), medium dose (50 µl / 100 µl sham) and high dose (75 µl / 75 µl sham) nonylphenol administered group. After 24 hours, the rats were euthanized and analyzed to detect DNA damage by determining the polychromatic erythrocyte/Normochromatic erythrocyte ratio and the number of micronucleated polychromatic erythrocytes in the femur bone marrow cells. While polychromatic erythrocyte/Normochromatic erythrocyte ratio was found to be lower in the groups treated with different doses of nonylphenol, especially in the group treated with high-dose nonylphenol, this decrease was not statistically significant. When the micronucleated polychromatic erythrocyte values were examined, it was observed that there was a statistically significant increase, especially in the medium and high dose groups compared to the control (p=0.0002, p","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132200258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nehir Uyar, A. Marangoz, Sefa Kocabaş, S. Mutlu, H. Atabay
It is costly and time-consuming to determine coastal pollution with ground measurements. One of the most basic parameters to determine pollution in these areas is Chlorophyll A. This study aims to investigate the determination of this parameter using Remote Sensing (RS) techniques. In the study, the Sentinel-2 satellite was used to determine the parameter Chlorophyll A in the coastal areas of the Black Sea. 19 algorithms were used in the application. The algorithms are related to luminance reflections and the 8 bands of the satellite were used for the study. An Artificial Neural Network model was published as the best result. Pollution was observed in the coastal areas of the Black Sea between 2021 and 2017. As a result of the analysis, it is possible to observe coastal pollution quickly, without cost and/or at very low cost, with RS techniques. In this sense, RS techniques are of great importance in detecting environmental pollution, and relevant algorithms should be developed and supported by local measurements.
{"title":"Detection of Chlorophyll A on the Black Sea Coast with Sentinel-2 Satellite","authors":"Nehir Uyar, A. Marangoz, Sefa Kocabaş, S. Mutlu, H. Atabay","doi":"10.32571/ijct.1201634","DOIUrl":"https://doi.org/10.32571/ijct.1201634","url":null,"abstract":"It is costly and time-consuming to determine coastal pollution with ground measurements. One of the most basic parameters to determine pollution in these areas is Chlorophyll A. This study aims to investigate the determination of this parameter using Remote Sensing (RS) techniques. In the study, the Sentinel-2 satellite was used to determine the parameter Chlorophyll A in the coastal areas of the Black Sea. 19 algorithms were used in the application. The algorithms are related to luminance reflections and the 8 bands of the satellite were used for the study. An Artificial Neural Network model was published as the best result. Pollution was observed in the coastal areas of the Black Sea between 2021 and 2017. As a result of the analysis, it is possible to observe coastal pollution quickly, without cost and/or at very low cost, with RS techniques. In this sense, RS techniques are of great importance in detecting environmental pollution, and relevant algorithms should be developed and supported by local measurements.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131217419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The release of greenhouse gas emissions into the atmosphere as a result of anthropogenic sources and industrial applications has triggered the increase in global temperatures called global warming and related climate change. Phosphogypsum (PG) is a by-product of the wet process phosphoric acid (H3PO4) production process, which chemically consists of calcium sulfate dihydrate (CaSO4•2H2O) with some impurities. Annual PG accumulation has reached 300 Mtons and a strategy is needed to ensure efficient, continuous and bulk consumption. Due to the high amount of calcium it contains, PG is a material suitable for use in CO2 capture and storage processes to form stable solid carbonate compounds. This process, called mineral carbonization of PG, contributes to sustainable development goals by providing the multiple benefits of both the utilization of an industrial by-product and the realization of CO2 capture and storage technology.
{"title":"EFFECT OF PHOSPHOGYPSUM USE AS A WASTE RECYCLING ON GHG EMISSIONS BY MINERAL CARBONISATION METHOD","authors":"A. O. Gezerman","doi":"10.32571/ijct.1187158","DOIUrl":"https://doi.org/10.32571/ijct.1187158","url":null,"abstract":"The release of greenhouse gas emissions into the atmosphere as a result of anthropogenic sources and industrial applications has triggered the increase in global temperatures called global warming and related climate change. Phosphogypsum (PG) is a by-product of the wet process phosphoric acid (H3PO4) production process, which chemically consists of calcium sulfate dihydrate (CaSO4•2H2O) with some impurities. Annual PG accumulation has reached 300 Mtons and a strategy is needed to ensure efficient, continuous and bulk consumption. Due to the high amount of calcium it contains, PG is a material suitable for use in CO2 capture and storage processes to form stable solid carbonate compounds. This process, called mineral carbonization of PG, contributes to sustainable development goals by providing the multiple benefits of both the utilization of an industrial by-product and the realization of CO2 capture and storage technology.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131693855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aims to explain the relationship between green economy, green finance and the environment. Environmental sensitivities have become related to production with the increase in global warming, greenhouse gas emissions and carbon emission rates. After becoming related to production and economy, some financial instruments have emerged in order to be sensitive to the environment. The purpose of these products is primarily to protect the environment and to include environmentally conscious people in this financial system. In the personal or individual green finance dimension, green mortgages, green home loans, green commercial building loans, green car loans and green credit cards are the most prominent green financing. In the green finance dimension related to companies; some products such as green project finance, green securities, green technology leasing, carbon finance. Eco fund and carbon fund in asset management, and car insurance, carbon insurance and green insurance in insurance. Considering that our environment is essential for all humanity, it is seen that supporting and increasing green financing products that are environmentally sensitive will make more positive contributions both for our country and for the world.
{"title":"A Look At The Relationship Between Green Finance And The Environment","authors":"Yunus Emre Kahraman","doi":"10.32571/ijct.1199748","DOIUrl":"https://doi.org/10.32571/ijct.1199748","url":null,"abstract":"This study aims to explain the relationship between green economy, green finance and the environment. Environmental sensitivities have become related to production with the increase in global warming, greenhouse gas emissions and carbon emission rates. After becoming related to production and economy, some financial instruments have emerged in order to be sensitive to the environment. The purpose of these products is primarily to protect the environment and to include environmentally conscious people in this financial system. In the personal or individual green finance dimension, green mortgages, green home loans, green commercial building loans, green car loans and green credit cards are the most prominent green financing. In the green finance dimension related to companies; some products such as green project finance, green securities, green technology leasing, carbon finance. Eco fund and carbon fund in asset management, and car insurance, carbon insurance and green insurance in insurance. Considering that our environment is essential for all humanity, it is seen that supporting and increasing green financing products that are environmentally sensitive will make more positive contributions both for our country and for the world.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"216 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115513020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Geometridae is one of the most populous families in terms of the number of species in the order Lepidoptera. It is known to have more than 23,000 species worldwide. Geometridae species cause damage to forest trees, but it has been reported that they also cause damage to cultivated plants in studies. This research was carried out in Turkey's Central Black Sea Region (Amasya, Çorum, Ordu, Samsun, Sinop, Tokat, and Yozgat) in 2017 and 2018 years. Adult specimens of Geometridae were collected using an insect net and a light trap in the study region. Obtained specimens were prepared according to standard museum methods for butterflies and prepared genitalia structures. As a result of the study, five subfamilies (Ennominae, Geometrinae, Larentiinae, Orthostixinae, Sterrhinae), 36 genera, and 48 species were determined. Also in this paper, the examined materials and adult photographs of the species are given. This study provides new information about the zoogeographic distribution of Geometridae species identified in the research area.
{"title":"Contributions to the fauna of Türkiye Geometridae","authors":"M. Koyuncu, V. Görmez, M. Kütük","doi":"10.32571/ijct.1170566","DOIUrl":"https://doi.org/10.32571/ijct.1170566","url":null,"abstract":"The Geometridae is one of the most populous families in terms of the number of species in the order Lepidoptera. It is known to have more than 23,000 species worldwide. Geometridae species cause damage to forest trees, but it has been reported that they also cause damage to cultivated plants in studies. This research was carried out in Turkey's Central Black Sea Region (Amasya, Çorum, Ordu, Samsun, Sinop, Tokat, and Yozgat) in 2017 and 2018 years. Adult specimens of Geometridae were collected using an insect net and a light trap in the study region. Obtained specimens were prepared according to standard museum methods for butterflies and prepared genitalia structures. As a result of the study, five subfamilies (Ennominae, Geometrinae, Larentiinae, Orthostixinae, Sterrhinae), 36 genera, and 48 species were determined. Also in this paper, the examined materials and adult photographs of the species are given. This study provides new information about the zoogeographic distribution of Geometridae species identified in the research area.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129879843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bedriye Seda KURŞUN AKTAR, Ş. Adem, E. E. Oruç-Emre
Inhibitors of xanthine oxidase (XO) are effective and most major therapeutic drugs for the management of gout. Chalcone compounds are important in terms of biological activity and have great importance in enzyme studies in recent years. In the presented study, the effects of some chalcones on the enzyme were tested in vitro by the spectrophotometric method. Compounds showed an inhibitory effect between 7.21±0.07 and 13.78±0.13 µM IC50 values. The conformations and interactions of the compounds in the active site of the enzyme were determined by the molecular docking method using Molegro Virtual Docker software. Molecular modeling studies show that the B ring of chalcones has a significant contribution to the inhibition effect on the XO enzyme. The presented study suggests that chalcones may be a potential inhibitory group for XO.
{"title":"The Investigation of The Effect of Chalcones With Benzoic Acid On Xanthine Oxidase Inhibitor","authors":"Bedriye Seda KURŞUN AKTAR, Ş. Adem, E. E. Oruç-Emre","doi":"10.32571/ijct.1199221","DOIUrl":"https://doi.org/10.32571/ijct.1199221","url":null,"abstract":"Inhibitors of xanthine oxidase (XO) are effective and most major therapeutic drugs for the management of gout. Chalcone compounds are important in terms of biological activity and have great importance in enzyme studies in recent years. In the presented study, the effects of some chalcones on the enzyme were tested in vitro by the spectrophotometric method. Compounds showed an inhibitory effect between 7.21±0.07 and 13.78±0.13 µM IC50 values. The conformations and interactions of the compounds in the active site of the enzyme were determined by the molecular docking method using Molegro Virtual Docker software. Molecular modeling studies show that the B ring of chalcones has a significant contribution to the inhibition effect on the XO enzyme. The presented study suggests that chalcones may be a potential inhibitory group for XO.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"272 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127713000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yerli ve ithal Hypericum perforatum sulu ekstraktlarının kimyasal içeriği ve biyoaktif kapasitesinin karşılaştırılması ÖZET Sarı kantaron olarak bilinen ve etnaformakoljik olarak en çok kullanılan Hypericum perforatum, Hypericaceae familyasına ait bir bitkidir. Bu çalışmada yerli ve ithal H. perforatum sulu ekstraktlarının antioksidan, antimikrobiyal, DNA koruyucu aktiviteleri ve enzim inhibitör özelliklerini değerlendirmeyi amaçladık. Her iki örnek için de toplam fenolik ve flavonoid içerikleri belirlendi. Analiz sonuçları, DHPE (Yerli H. perforatum sulu özüt) ve IHPE (İthal H. perforatum sulu özüt) numuneleri için yüksek fenolik içerikti. Numunelerin diyabetle ilgili temel enzimlere karşı inhibisyon aktivitesi seviyeleri çarpıcıydı; α-glukosidaza gelince, DHPE'nin IC50 değeri 16.35±0.07 µg/mL idi ve IHPE'nin IC50 değeri 15.05±1.36 µg/mL idi, bu da sırasıyla enzimin standart inhibitörünün etkinliğinin neredeyse iki katını temsil ediyor. Özellikle, DHPE'nin α-amilaz ve α-glukosidaz üzerindeki inhibisyon aktivitelerinin akarboza göre daha etkili olduğu belirlendi (IC50: 30.62±2.07 µg/mL). Antibakteriyel test şu şekildeydi; en yüksek MİK değeri IHPE tarafından B. cereus'a karşı 64 µg/mL olarak tespit edildi. Ayrıca, IHPE yerli örnekten daha etkiliydi. DHPE, oksidatif H2O2 ile indüklenen DNA hasarından iyi koruyucu aktivite sergiledi. Sonuç olarak, test edilen her iki numune de bol miktarda fenolik içeriğe sahipti ve diyabetik enzimlere karşı inhibitör aktivitelerinde yüksekti. Ayrıca, diğer biyoaktivite testleri, standartlara göre oldukça etkili olduğu gözlendi. Anahtar Kelimeler: H. perforatum, sulu ekstrakt, fitokimyasal içerik, biyoaktivite
{"title":"The comparison of chemical content and bioactive capacity of domestic and import Hypericum perforatum aqueous extracts","authors":"Sarmad Marah, I. Demirtaş, T. Ozen","doi":"10.32571/ijct.1187768","DOIUrl":"https://doi.org/10.32571/ijct.1187768","url":null,"abstract":"Yerli ve ithal Hypericum perforatum sulu ekstraktlarının kimyasal içeriği ve biyoaktif kapasitesinin karşılaştırılması \u0000 \u0000ÖZET \u0000Sarı kantaron olarak bilinen ve etnaformakoljik olarak en çok kullanılan Hypericum perforatum, Hypericaceae familyasına ait bir bitkidir. Bu çalışmada yerli ve ithal H. perforatum sulu ekstraktlarının antioksidan, antimikrobiyal, DNA koruyucu aktiviteleri ve enzim inhibitör özelliklerini değerlendirmeyi amaçladık. Her iki örnek için de toplam fenolik ve flavonoid içerikleri belirlendi. Analiz sonuçları, DHPE (Yerli H. perforatum sulu özüt) ve IHPE (İthal H. perforatum sulu özüt) numuneleri için yüksek fenolik içerikti. Numunelerin diyabetle ilgili temel enzimlere karşı inhibisyon aktivitesi seviyeleri çarpıcıydı; α-glukosidaza gelince, DHPE'nin IC50 değeri 16.35±0.07 µg/mL idi ve IHPE'nin IC50 değeri 15.05±1.36 µg/mL idi, bu da sırasıyla enzimin standart inhibitörünün etkinliğinin neredeyse iki katını temsil ediyor. Özellikle, DHPE'nin α-amilaz ve α-glukosidaz üzerindeki inhibisyon aktivitelerinin akarboza göre daha etkili olduğu belirlendi (IC50: 30.62±2.07 µg/mL). Antibakteriyel test şu şekildeydi; en yüksek MİK değeri IHPE tarafından B. cereus'a karşı 64 µg/mL olarak tespit edildi. Ayrıca, IHPE yerli örnekten daha etkiliydi. DHPE, oksidatif H2O2 ile indüklenen DNA hasarından iyi koruyucu aktivite sergiledi. Sonuç olarak, test edilen her iki numune de bol miktarda fenolik içeriğe sahipti ve diyabetik enzimlere karşı inhibitör aktivitelerinde yüksekti. Ayrıca, diğer biyoaktivite testleri, standartlara göre oldukça etkili olduğu gözlendi. \u0000 \u0000Anahtar Kelimeler: H. perforatum, sulu ekstrakt, fitokimyasal içerik, biyoaktivite","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128398993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suyun elektroliziyle hidrojen üretiminde ekonomik ve etkin elektrokatalizlerin geliştirilmesi oldukça önemlidir. Bu çalışmada, nikel nanoparçacıklarla dekore edilmiş indirgenmiş grafen oksit (rGO) bazlı bir elektrokatalizörün basit bir tasarımı anlatılmaktadır. Voltametrik çalışmaların ve hidrojen oluşumu reaksiyonu (HER) kinetiğinin sonuçları, 152 mVdec-1’lık düşük Tafel eğimi ve 0,5 M H2SO4 çözeltisi içinde uzun süreli gösterdiği dayanıklılık (24 saatin üzerinde) ile hazırlanan nanokompozitin, hidrojen üretimi için etkili ve kararlı bir elektrokatalizör olduğunu göstermiştir. Ayrıca karakterizasyon sonuçları, gözenekli/daha yüksek elektroaktif yüzey alanıyla HER aktivitesinin arttığını doğrulamıştır. Elektrokatalitik aktivitedeki dikkate değer artış, yüzey pürüzlülüğünden ve rGO ile Ni nanopartiküller arasındaki kimyasal etkileşmelerin sinerjik etkilerinden kaynaklanmaktadır.
{"title":"Hydrogen Production via Water Electrolysis on an Active Electrocatalyst: rGO/Ni nanocomposite","authors":"Didem Balun Kayan","doi":"10.32571/ijct.1199967","DOIUrl":"https://doi.org/10.32571/ijct.1199967","url":null,"abstract":"Suyun elektroliziyle hidrojen üretiminde ekonomik ve etkin elektrokatalizlerin geliştirilmesi oldukça önemlidir. Bu çalışmada, nikel nanoparçacıklarla dekore edilmiş indirgenmiş grafen oksit (rGO) bazlı bir elektrokatalizörün basit bir tasarımı anlatılmaktadır. Voltametrik çalışmaların ve hidrojen oluşumu reaksiyonu (HER) kinetiğinin sonuçları, 152 mVdec-1’lık düşük Tafel eğimi ve 0,5 M H2SO4 çözeltisi içinde uzun süreli gösterdiği dayanıklılık (24 saatin üzerinde) ile hazırlanan nanokompozitin, hidrojen üretimi için etkili ve kararlı bir elektrokatalizör olduğunu göstermiştir. Ayrıca karakterizasyon sonuçları, gözenekli/daha yüksek elektroaktif yüzey alanıyla HER aktivitesinin arttığını doğrulamıştır. Elektrokatalitik aktivitedeki dikkate değer artış, yüzey pürüzlülüğünden ve rGO ile Ni nanopartiküller arasındaki kimyasal etkileşmelerin sinerjik etkilerinden kaynaklanmaktadır.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123378426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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