Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145196
I. Spano, S. Sulis, A. Serpi, I. Marongiu, G. Gatto, V. Nissardi
An Automatic Sensing Test procedure (AST) for evaluating the sensing performances of Implantable Cardioverter Defibrillators (ICDs) is presented in this paper. AST is based on the Sensitivity Test described by the Standard CEI EN 45502-2-1 for pacemakers and consists of determining the ICD sensing thresholds at different heartbeat frequencies. Consequently, an extensive evaluation of ICD sensing performances can be achieved. AST has been implemented by means of virtual instruments developed in the Labview environment and has been validated experimentally through several tests. These have been performed inside an anechoic RF chamber. Such an environment guarantees proper shielding against external electromagnetic interferences, thus ensuring reliability and repeatability of the tests. The discussion of the results highlights the usefulness of the proposed procedure.
本文提出了一种用于评估植入式心律转复除颤器(ICDs)感知性能的自动感知测试程序(AST)。AST是基于标准CEI EN 45502-2-1对起搏器描述的灵敏度测试，包括确定不同心跳频率下的ICD传感阈值。因此，可以实现对ICD传感性能的广泛评估。AST采用Labview环境下开发的虚拟仪器实现，并通过多次实验验证。这些都是在消声射频室中进行的。这样的环境保证了对外部电磁干扰的适当屏蔽，从而确保了测试的可靠性和可重复性。对结果的讨论突出了所建议程序的有效性。
{"title":"An Automatic Sensing Test procedure for Implantable Cardioverter Defibrillators","authors":"I. Spano, S. Sulis, A. Serpi, I. Marongiu, G. Gatto, V. Nissardi","doi":"10.1109/MeMeA.2015.7145196","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145196","url":null,"abstract":"An Automatic Sensing Test procedure (AST) for evaluating the sensing performances of Implantable Cardioverter Defibrillators (ICDs) is presented in this paper. AST is based on the Sensitivity Test described by the Standard CEI EN 45502-2-1 for pacemakers and consists of determining the ICD sensing thresholds at different heartbeat frequencies. Consequently, an extensive evaluation of ICD sensing performances can be achieved. AST has been implemented by means of virtual instruments developed in the Labview environment and has been validated experimentally through several tests. These have been performed inside an anechoic RF chamber. Such an environment guarantees proper shielding against external electromagnetic interferences, thus ensuring reliability and repeatability of the tests. The discussion of the results highlights the usefulness of the proposed procedure.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124714550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145220
R. Marco, S. Rossi, Benedetta Bachetti, C. Mazzà, P. Cappa
Optoelectronic systems are largely employed for human movement analysis, where marker trajectories are used to estimate the articular joint kinematics. From a literature analysis it emerged that the error associated to the joint kinematics can be reduced performing the data collection in the center of the system calibration volume. According to human movement analysis literature, the foot-ankle complex appears to be the anatomical joint most affected by instrument inaccuracy, as it moves in the lower bound of the calibration volume during the gait cycle. A multi-segment marker-based model of the lower limb - including the pelvis, thigh, tibia, hindfoot, forefoot and hallux - was investigated in this paper. One healthy subject was asked to walk on the central and on two boundary areas of the capture volume calibrated for the experiments. The calibration procedure was focused on the exploitation of the effects on the joint angles of: (i) calibration volumes (i.e. the global one and two of its sub-volumes) and (ii) number of frames acquired for the calibration procedure (refinement frames). In order to quantify the precision of estimating the joint kinematics when changing the calibration procedure, the RMSE among different refinement frames using both the global volume and the two sub-volumes was computed as an index of the joint angles variation estimated on the sagittal plane. Two two-way ANOVAs were performed to evaluate whether the calibration volumes or the walking areas affect the kinematics. The statistical analysis highlighted a good robustness of the reconstruction algorithm implemented by the optoelectronic system manufacturer. Few variables showed significant differences for the RMSEs, with p-values lower than 0.05. No clear dependence on the body segments here analyzed emerged from the analysis. The coefficient of Multiple Correlations was computed in order to enlighten the similarities among the joint angles time patterns. We conclude that reconstructed trajectories can be affected by the same magnitude errors, regardless to the calibrated volume or the considered walking area. This finding allows conducting the gait analysis without paying attention when calibrating the system and without having to impose excessive restrictions to the tested subjects, allowing to keep their movement as natural as possible.
{"title":"Effect of the calibration procedure of an optoelectronic system on the joint kinematics","authors":"R. Marco, S. Rossi, Benedetta Bachetti, C. Mazzà, P. Cappa","doi":"10.1109/MeMeA.2015.7145220","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145220","url":null,"abstract":"Optoelectronic systems are largely employed for human movement analysis, where marker trajectories are used to estimate the articular joint kinematics. From a literature analysis it emerged that the error associated to the joint kinematics can be reduced performing the data collection in the center of the system calibration volume. According to human movement analysis literature, the foot-ankle complex appears to be the anatomical joint most affected by instrument inaccuracy, as it moves in the lower bound of the calibration volume during the gait cycle. A multi-segment marker-based model of the lower limb - including the pelvis, thigh, tibia, hindfoot, forefoot and hallux - was investigated in this paper. One healthy subject was asked to walk on the central and on two boundary areas of the capture volume calibrated for the experiments. The calibration procedure was focused on the exploitation of the effects on the joint angles of: (i) calibration volumes (i.e. the global one and two of its sub-volumes) and (ii) number of frames acquired for the calibration procedure (refinement frames). In order to quantify the precision of estimating the joint kinematics when changing the calibration procedure, the RMSE among different refinement frames using both the global volume and the two sub-volumes was computed as an index of the joint angles variation estimated on the sagittal plane. Two two-way ANOVAs were performed to evaluate whether the calibration volumes or the walking areas affect the kinematics. The statistical analysis highlighted a good robustness of the reconstruction algorithm implemented by the optoelectronic system manufacturer. Few variables showed significant differences for the RMSEs, with p-values lower than 0.05. No clear dependence on the body segments here analyzed emerged from the analysis. The coefficient of Multiple Correlations was computed in order to enlighten the similarities among the joint angles time patterns. We conclude that reconstructed trajectories can be affected by the same magnitude errors, regardless to the calibrated volume or the considered walking area. This finding allows conducting the gait analysis without paying attention when calibrating the system and without having to impose excessive restrictions to the tested subjects, allowing to keep their movement as natural as possible.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131298149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145186
B. Karaboce
The temperature distribution produced by a HIFU (High Intensity Focused Ultrasound) transducer has been investigated by a set up using T type thermocouple temperature sensors in the automated scanning system. The temperature change and the temperature distribution due to applied ultrasound power have been characterized. The temperature measurements were carried out in a tissue-mimicking material (TMM) that has characteristics very similar to human tissue and in ex vivo tissue. A temperature measurement set up in a tissue phantom has been constructed at TÜBİTAK UME (The Scientific and Technological Research Council of Turkey, the National Metrology Institute) Ultrasound laboratory. Burning and removing the tissue by high power ultrasound have been showed.
{"title":"Focused ultrasound temperature effect in tissue-mimicking material and sheep liver","authors":"B. Karaboce","doi":"10.1109/MeMeA.2015.7145186","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145186","url":null,"abstract":"The temperature distribution produced by a HIFU (High Intensity Focused Ultrasound) transducer has been investigated by a set up using T type thermocouple temperature sensors in the automated scanning system. The temperature change and the temperature distribution due to applied ultrasound power have been characterized. The temperature measurements were carried out in a tissue-mimicking material (TMM) that has characteristics very similar to human tissue and in ex vivo tissue. A temperature measurement set up in a tissue phantom has been constructed at TÜBİTAK UME (The Scientific and Technological Research Council of Turkey, the National Metrology Institute) Ultrasound laboratory. Burning and removing the tissue by high power ultrasound have been showed.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131889798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145205
F. Montecchia, S. Luciani, R. Cicchetti, Rosanna Grossi, F. Midulla, C. Moretti, P. Papoff
High-flow humidified nasal cannula (HFNC) is often used to relieve respiratory distress in children with acute pulmonary disease, although its effects on respiratory mechanics have not been objectively studied. The purpose of this study was to test the feasibility of measuring pharyngeal (PP) and esophageal (Pes) pressures of young children on HFNC oxygen therapy through a specifically designed new monitoring, acquisition, and elaboration system (MAES). Through MAES we recorded and elaborated Pes and PP tracings obtained through esophageal and pharyngeal catheters in a group of young children hospitalized in a Pediatric Intensive Care Unit because of respiratory distress. All traces were recorded during spontaneous breathing and on HFNC 1 and 2 L/kg/min. To determine the onset and the end of inspiration, the Pes and PP signals were synchronized with the inspiratory flow obtained by a flow transducer placed in the HFNC circuit. Direct measurement of inspiratory flow by a face mask pneumotachograph also allowed for inspiratory tidal volume (TV) measurement which was used together with Pes curve to build Campbell's diagram as well as the static lung and chest wall recoil curves required for pressure time product (PTP) evaluation. Using MAES we were able to obtain: time interval between the beginning of inspiratory effort and inspiration (Tdelay), TV, intrinsic positive end expiratory pressure (PEEPi), total inspiratory Pes variation (ΔPes), transpulmonary pressure at end of inspiration (Ptpei), dynamic lung compliance (CLdyn), total lung resistance (RLtot) along with all the relevant components of the inspiratory work of breathing (WOB) and PTP. We believe that this new system will allow clinicians for a bedside monitoring of respiratory distress in infants treated with HFNC and to modify flow rates accordingly.
{"title":"Pharyngeal and esophageal pressure measurements to evaluate respiratory mechanics in infants on high flow nasal cannula: A feasibility study","authors":"F. Montecchia, S. Luciani, R. Cicchetti, Rosanna Grossi, F. Midulla, C. Moretti, P. Papoff","doi":"10.1109/MeMeA.2015.7145205","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145205","url":null,"abstract":"High-flow humidified nasal cannula (HFNC) is often used to relieve respiratory distress in children with acute pulmonary disease, although its effects on respiratory mechanics have not been objectively studied. The purpose of this study was to test the feasibility of measuring pharyngeal (PP) and esophageal (Pes) pressures of young children on HFNC oxygen therapy through a specifically designed new monitoring, acquisition, and elaboration system (MAES). Through MAES we recorded and elaborated Pes and PP tracings obtained through esophageal and pharyngeal catheters in a group of young children hospitalized in a Pediatric Intensive Care Unit because of respiratory distress. All traces were recorded during spontaneous breathing and on HFNC 1 and 2 L/kg/min. To determine the onset and the end of inspiration, the Pes and PP signals were synchronized with the inspiratory flow obtained by a flow transducer placed in the HFNC circuit. Direct measurement of inspiratory flow by a face mask pneumotachograph also allowed for inspiratory tidal volume (TV) measurement which was used together with Pes curve to build Campbell's diagram as well as the static lung and chest wall recoil curves required for pressure time product (PTP) evaluation. Using MAES we were able to obtain: time interval between the beginning of inspiratory effort and inspiration (Tdelay), TV, intrinsic positive end expiratory pressure (PEEPi), total inspiratory Pes variation (ΔPes), transpulmonary pressure at end of inspiration (Ptpei), dynamic lung compliance (CLdyn), total lung resistance (RLtot) along with all the relevant components of the inspiratory work of breathing (WOB) and PTP. We believe that this new system will allow clinicians for a bedside monitoring of respiratory distress in infants treated with HFNC and to modify flow rates accordingly.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133517523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145254
Aydin Saribudak, S. Gundry, Jianmin Zou, M. U. Uyar
Personalized approach to anti-cancer therapy necessitates the adaptation of standardized guidelines for chemotherapy schedules to individual cancer patients. We introduce a methodology, namely Personalized Relevance Parameterization (PReP-G), based on the genomic data of breast cancer patients to compute time course of drug efficacy on tumor progression. The pharmacodynamic (PD) parameters of transit compartmental systems are computed to quantify the drug efficacy and kinetics of cell death. We integrate the genetic information of 74 breast cancer related genes for 78 patients with clinical t-stage of 3 from the I-SPY 1 TRIAL with the tumor volume measurements from NBIA database into our PReP-G model to compute tumor growth and shrinkage parameters. The performance of the method is evaluated for the breast cancer cell lines of BT-474, MDA-MB-435 and MDA-MB-231 for a given chemotherapy, where the anti-cancer agents Doxorubicin and Cyclophosphamide are administered to animal models and the change of tumor size is measured in time. We compare our results from PReP-G model with the experimental measurements. The consistency between computed results and the volume measurements is encouraging to develop personalized tumor growth models and decision support systems based on genetic data.
{"title":"Genomic based personalized chemotherapy analysis to support decision systems for breast cancer","authors":"Aydin Saribudak, S. Gundry, Jianmin Zou, M. U. Uyar","doi":"10.1109/MeMeA.2015.7145254","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145254","url":null,"abstract":"Personalized approach to anti-cancer therapy necessitates the adaptation of standardized guidelines for chemotherapy schedules to individual cancer patients. We introduce a methodology, namely Personalized Relevance Parameterization (PReP-G), based on the genomic data of breast cancer patients to compute time course of drug efficacy on tumor progression. The pharmacodynamic (PD) parameters of transit compartmental systems are computed to quantify the drug efficacy and kinetics of cell death. We integrate the genetic information of 74 breast cancer related genes for 78 patients with clinical t-stage of 3 from the I-SPY 1 TRIAL with the tumor volume measurements from NBIA database into our PReP-G model to compute tumor growth and shrinkage parameters. The performance of the method is evaluated for the breast cancer cell lines of BT-474, MDA-MB-435 and MDA-MB-231 for a given chemotherapy, where the anti-cancer agents Doxorubicin and Cyclophosphamide are administered to animal models and the change of tumor size is measured in time. We compare our results from PReP-G model with the experimental measurements. The consistency between computed results and the volume measurements is encouraging to develop personalized tumor growth models and decision support systems based on genetic data.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124478244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145239
Johannes C. Ayena, Landry Delphin Chapwouo Tchakouté, M. Otis, B. Ménélas
The aim of this study is to improve and facilitate the methods used to assess risk of falling among older people at home. We propose an automatic version of One-Leg Standing (OLS) test for risk of falling assessment by using a Smartphone and an instrumented insole. For better clinical assessment tests, this study focuses on exploring methods to combine the most important parameters of risk of falling into a single score. Twenty-three volunteers participated in this study for evaluating the effectiveness of the proposed system which includes eleven elderly participants: seven healthy elderly (67.16 ± 4.24 years), four Parkinson disease (PD) subjects (70 ± 12.73 years); and twelve healthy young adults (28.27 ± 3.74 years). Our work suggests that there is an inverse relationship between OLS score proposed and risk of falling. Proposed instrumented insole and application running on Android could be useful at home as a diagnostic aid tool for analyzing the performance of elderly people in OLS test.
{"title":"An efficient home-based risk of falling assessment test based on Smartphone and instrumented insole","authors":"Johannes C. Ayena, Landry Delphin Chapwouo Tchakouté, M. Otis, B. Ménélas","doi":"10.1109/MeMeA.2015.7145239","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145239","url":null,"abstract":"The aim of this study is to improve and facilitate the methods used to assess risk of falling among older people at home. We propose an automatic version of One-Leg Standing (OLS) test for risk of falling assessment by using a Smartphone and an instrumented insole. For better clinical assessment tests, this study focuses on exploring methods to combine the most important parameters of risk of falling into a single score. Twenty-three volunteers participated in this study for evaluating the effectiveness of the proposed system which includes eleven elderly participants: seven healthy elderly (67.16 ± 4.24 years), four Parkinson disease (PD) subjects (70 ± 12.73 years); and twelve healthy young adults (28.27 ± 3.74 years). Our work suggests that there is an inverse relationship between OLS score proposed and risk of falling. Proposed instrumented insole and application running on Android could be useful at home as a diagnostic aid tool for analyzing the performance of elderly people in OLS test.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125884417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145197
Ting-Ying Wei, C. Young
Past researches showed that neurofeedback training can enhance cognitive function. This study used alpha rhythm (8-12Hz) to conduct brain induced training. It proposed the use of Bluetooth Low Energy to connect the EEG signals to the smartphone. Then, the pattern of the interface will display the induced alpha energy. The result of the experiment indicates that the alpha power showed on the phone has a significant memory increase in the results of the memory of cognitive brain training.
{"title":"A mobile approach for neurofeedback cognitive enhancement","authors":"Ting-Ying Wei, C. Young","doi":"10.1109/MeMeA.2015.7145197","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145197","url":null,"abstract":"Past researches showed that neurofeedback training can enhance cognitive function. This study used alpha rhythm (8-12Hz) to conduct brain induced training. It proposed the use of Bluetooth Low Energy to connect the EEG signals to the smartphone. Then, the pattern of the interface will display the induced alpha energy. The result of the experiment indicates that the alpha power showed on the phone has a significant memory increase in the results of the memory of cognitive brain training.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124050275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145228
F. Lamonaca, D. L. Carní, D. Grimaldi, A. Nastro, M. Riccio, V. Spagnuolo
This study investigates the usability of the smartphone camera for the evaluation of arterial blood oxygenation (SpO2%). The advantage of this solution derives from the pervasiveness of the smartphone that makes available the evaluation of the SpO2% everywhere. Differently from the pulse oximeter, which uses well-defined wavelength light, the smartphone uses Light Emitting Diodes as a light source to evaluate the SpO2%. The change of the light intensity in the Red and Green colour channels in the video frames of the patient fingertip are properly processed. Two PPG signals are obtained at the wavelengths 600nm and 940nm, respectively. These two PPGs are used to evaluate the SpO2% without calibration coefficients and independently of the smartphone hardware and skin characteristics. Experimental tests are performed to compare the proposed procedure with respect to a commercial pulse oximeter and gas chromatograph. The experimental tests assess the effectiveness of the proposal.
{"title":"Blood oxygen saturation measurement by smartphone camera","authors":"F. Lamonaca, D. L. Carní, D. Grimaldi, A. Nastro, M. Riccio, V. Spagnuolo","doi":"10.1109/MeMeA.2015.7145228","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145228","url":null,"abstract":"This study investigates the usability of the smartphone camera for the evaluation of arterial blood oxygenation (SpO2%). The advantage of this solution derives from the pervasiveness of the smartphone that makes available the evaluation of the SpO2% everywhere. Differently from the pulse oximeter, which uses well-defined wavelength light, the smartphone uses Light Emitting Diodes as a light source to evaluate the SpO2%. The change of the light intensity in the Red and Green colour channels in the video frames of the patient fingertip are properly processed. Two PPG signals are obtained at the wavelengths 600nm and 940nm, respectively. These two PPGs are used to evaluate the SpO2% without calibration coefficients and independently of the smartphone hardware and skin characteristics. Experimental tests are performed to compare the proposed procedure with respect to a commercial pulse oximeter and gas chromatograph. The experimental tests assess the effectiveness of the proposal.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117174282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145256
Katarzyna Polak-Kraśna, A. Georgiadis, P. Heikkila
Electrospun nonwovens, due to their intrinsic beneficial properties, have found many applications in biomedical areas such as tissue engineering, drug delivery, or active wound management. Exploiting its porous structure, electrospun is often used as scaffolds for tissue growth which can be stimulated by mechanical properties of the structure. Cells proliferation can be controlled by stress distribution in the scaffold, thus improving its efficiency. Anticipation of this parameter is possible by using Finite Elements Model of electrospun structure presented in this study. Fully parametric model of nonwoven material with random fibrous distribution was developed enabling the calculation of mechanical properties of material on the basis of input parameters such as mechanical characteristics and geometry of single component fibres. Relatively low production ratio of electrospinning process and time consuming characterisation methods were motivation to develop the tool that would shorten the design and optimisation of electrospun materials. The model was validated experimentally by mechanical testing of electrospun material; modelling and experimental results were in a good agreement.
{"title":"Mechanical characterisation and modelling of electrospun materials for biomedical applications","authors":"Katarzyna Polak-Kraśna, A. Georgiadis, P. Heikkila","doi":"10.1109/MeMeA.2015.7145256","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145256","url":null,"abstract":"Electrospun nonwovens, due to their intrinsic beneficial properties, have found many applications in biomedical areas such as tissue engineering, drug delivery, or active wound management. Exploiting its porous structure, electrospun is often used as scaffolds for tissue growth which can be stimulated by mechanical properties of the structure. Cells proliferation can be controlled by stress distribution in the scaffold, thus improving its efficiency. Anticipation of this parameter is possible by using Finite Elements Model of electrospun structure presented in this study. Fully parametric model of nonwoven material with random fibrous distribution was developed enabling the calculation of mechanical properties of material on the basis of input parameters such as mechanical characteristics and geometry of single component fibres. Relatively low production ratio of electrospinning process and time consuming characterisation methods were motivation to develop the tool that would shorten the design and optimisation of electrospun materials. The model was validated experimentally by mechanical testing of electrospun material; modelling and experimental results were in a good agreement.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128389696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MEMEA.2015.7145166
E. Fiorina, F. Pennazio, C. Peroni, E. L. Torres, M. Fantacci, A. Retico, L. Rei, A. Chincarini, P. Bosco, M. Boccardi, M. Bocchetta, P. Cerello
The hippocampus segmentation in Magnetic Resonance (MRI) scans is a relevant issue for the diagnosis of many pathologies. The present work describes a fully automated method for the hippocampal segmentation and discusses the results obtained on three datasets provided by different institutions and referring to different pathologies that involve hippocampus anatomy. The algorithm is based on an extension of the Channeler Ant Model, a powerful non linear segmentation tool belonging to the family of ant colony-based models, whose application to medical image processing already provided some promising results in the analysis of CT and PET scans. In this application, thanks to a modified pheromone deposition rule, both the grey matter intensity and the expected average hippocampus shape are taken into account. In this paper, the results on the three available datasets, obtained from the comparison to manual segmentations by different subjects and protocols, are shown: an average Dice Index in the 0.72- 0.79 range, depending on the analysed dataset, is reached.
{"title":"Automated hippocampus segmentation with the Channeler Ant Model: Results on different datasets","authors":"E. Fiorina, F. Pennazio, C. Peroni, E. L. Torres, M. Fantacci, A. Retico, L. Rei, A. Chincarini, P. Bosco, M. Boccardi, M. Bocchetta, P. Cerello","doi":"10.1109/MEMEA.2015.7145166","DOIUrl":"https://doi.org/10.1109/MEMEA.2015.7145166","url":null,"abstract":"The hippocampus segmentation in Magnetic Resonance (MRI) scans is a relevant issue for the diagnosis of many pathologies. The present work describes a fully automated method for the hippocampal segmentation and discusses the results obtained on three datasets provided by different institutions and referring to different pathologies that involve hippocampus anatomy. The algorithm is based on an extension of the Channeler Ant Model, a powerful non linear segmentation tool belonging to the family of ant colony-based models, whose application to medical image processing already provided some promising results in the analysis of CT and PET scans. In this application, thanks to a modified pheromone deposition rule, both the grey matter intensity and the expected average hippocampus shape are taken into account. In this paper, the results on the three available datasets, obtained from the comparison to manual segmentations by different subjects and protocols, are shown: an average Dice Index in the 0.72- 0.79 range, depending on the analysed dataset, is reached.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128685210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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