Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145202
E. Schena, P. Saccomandi, C. Massaroni, G. Frauenfelder, F. Giurazza, G. M. Peroglio, S. Silvestri, M. Caponero, A. Polimadei
Laser ablation (LA) is a minimally invasive procedure used to remove cancer by inducing hyperthermia. It is based on the interaction between laser light and tissue: the absorbed light is converted into heat causing a tissue temperature increase. The amount of damaged volume depends on temperature and time exposure of the tissue to the hyperthermia. As a consequence, the monitoring of tissue temperature during LA could be particularly beneficial to optimize treatment outcomes. Thermocouples are one of the most employed transducer for temperature measurement. Their main drawback is related to the strong light absorption of the two metallic wires which constitute a thermocouple. The light absorption causes an overestimation of actual temperature, in literature known as artifact. This work aims at assessing this artifact on ex vivo swine pancreases undergoing LA. The artifacts have been estimated at the three laser powers (1.6 W, 2 W and 5 W) and at two distances from the optical applicator. In particular, the artifact decreases with the distance from the optical applicator and depends on P: at 1.6 W and 2 W it is negligible at 12 mm of distance, on the other hand at 5 W it is significant also at 15 mm (1.7 °C). Summing up: the artifact is strongly influenced by the distance between the thermocouple and the optical applicator, and by the laser power; also at high distance from the applicator it can cause error which are not acceptable for the application of interest (e.g., at 5 W and 10 mm the error is about 4 °C). Although the use of thermocouples entails the concern related to the artifact, it must be considered that proper model can be employed to correct the measurement error.
{"title":"Thermocouples for temperature monitoring during pancreatic laser ablation: Analysis of the measurement error","authors":"E. Schena, P. Saccomandi, C. Massaroni, G. Frauenfelder, F. Giurazza, G. M. Peroglio, S. Silvestri, M. Caponero, A. Polimadei","doi":"10.1109/MeMeA.2015.7145202","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145202","url":null,"abstract":"Laser ablation (LA) is a minimally invasive procedure used to remove cancer by inducing hyperthermia. It is based on the interaction between laser light and tissue: the absorbed light is converted into heat causing a tissue temperature increase. The amount of damaged volume depends on temperature and time exposure of the tissue to the hyperthermia. As a consequence, the monitoring of tissue temperature during LA could be particularly beneficial to optimize treatment outcomes. Thermocouples are one of the most employed transducer for temperature measurement. Their main drawback is related to the strong light absorption of the two metallic wires which constitute a thermocouple. The light absorption causes an overestimation of actual temperature, in literature known as artifact. This work aims at assessing this artifact on ex vivo swine pancreases undergoing LA. The artifacts have been estimated at the three laser powers (1.6 W, 2 W and 5 W) and at two distances from the optical applicator. In particular, the artifact decreases with the distance from the optical applicator and depends on P: at 1.6 W and 2 W it is negligible at 12 mm of distance, on the other hand at 5 W it is significant also at 15 mm (1.7 °C). Summing up: the artifact is strongly influenced by the distance between the thermocouple and the optical applicator, and by the laser power; also at high distance from the applicator it can cause error which are not acceptable for the application of interest (e.g., at 5 W and 10 mm the error is about 4 °C). Although the use of thermocouples entails the concern related to the artifact, it must be considered that proper model can be employed to correct the measurement error.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123866193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145273
A. Ancillao, S. Rossi, F. Patané, P. Cappa
Strength measurements are popular in the clinical practice to evaluate the health status of patients and quantify the outcome of training programs. Currently a common method to measure strength is based on Hand Held Dynamometers (HHD) which is operator-dependent. Some studies were conducted on repeatability of strength measurements but they were limited to the statistical analysis of repeated measurements of force. In this work, the authors developed a methodology to study the quality of knee flexion/extension strength measurements by measuring the effective HHD position and orientation with respect to the patient. HHD positioning attitude was measured by means of an Optoelectronic System for which a marker protocol was defined ad-hoc. The approach allowed to assess quality of measurements and operator's ability by means of quantitative indices. The protocol permitted the evaluation of: angles of HHD application, angular range of motion of the knee and range of motion of the HHD. RMSE parameters allowed to quantify the inaccuracy associated to the selected indices. Results showed that the operator was not able to keep the subject's limb completely still. The force exerted by the subject was higher in knee extension and the knee range of motion was higher than expected, however the operator had more difficulties in holding the HHD in knee flexion trials. This work showed that HHD positioning should be as accurate as possible, as it plays an important role for the strength evaluation. Moreover, the operator should be properly trained and should be strong enough to counteract the force of the subject.
{"title":"A preliminary study on quality of knee strength measurements by means of Hand Held Dynamometer and Optoelectronic System","authors":"A. Ancillao, S. Rossi, F. Patané, P. Cappa","doi":"10.1109/MeMeA.2015.7145273","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145273","url":null,"abstract":"Strength measurements are popular in the clinical practice to evaluate the health status of patients and quantify the outcome of training programs. Currently a common method to measure strength is based on Hand Held Dynamometers (HHD) which is operator-dependent. Some studies were conducted on repeatability of strength measurements but they were limited to the statistical analysis of repeated measurements of force. In this work, the authors developed a methodology to study the quality of knee flexion/extension strength measurements by measuring the effective HHD position and orientation with respect to the patient. HHD positioning attitude was measured by means of an Optoelectronic System for which a marker protocol was defined ad-hoc. The approach allowed to assess quality of measurements and operator's ability by means of quantitative indices. The protocol permitted the evaluation of: angles of HHD application, angular range of motion of the knee and range of motion of the HHD. RMSE parameters allowed to quantify the inaccuracy associated to the selected indices. Results showed that the operator was not able to keep the subject's limb completely still. The force exerted by the subject was higher in knee extension and the knee range of motion was higher than expected, however the operator had more difficulties in holding the HHD in knee flexion trials. This work showed that HHD positioning should be as accurate as possible, as it plays an important role for the strength evaluation. Moreover, the operator should be properly trained and should be strong enough to counteract the force of the subject.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124928971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145218
G. Lupi, A. Scorza, Maria Livia Rugiano, S. Sciuto, F. Bini
Magnetic Resonance Imaging (MRI) scanners are widely used both for diagnostic purpose and in studies on material properties. As a consequence they play an important role in diagnosis of diseases and in materials investigations. MRI Quality assurance tests are mandatory to obtain and maintain optimal images during time, some institutional organizations have proposed requirements on MRI image quality even if there are no worldwide standardization procedures .The purpose of this study is to design a novel MRI phantom useful to evaluate basic image quality requirements: our phantom is designed, realized and tested in order to define specific image assurance protocols and tests. Moreover the developed device is low cost, reusable and can be filled with different MRI-compatible materials. In our application the phantom is filled with water and paraffin to compare contrast resolution and signal-to-noise ratio measurements for a same scanner. Tests have been performed on a 3T scanner with 7 different scansion settings. First experimental results are encouraging and confirm a previous theoretical investigation on the employed material characteristics. Therefore other tests and data are going to be collected for the future development and performance improvement of the device.
{"title":"Preliminary study for a water-paraffin based phantom in MRI quality assurance test","authors":"G. Lupi, A. Scorza, Maria Livia Rugiano, S. Sciuto, F. Bini","doi":"10.1109/MeMeA.2015.7145218","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145218","url":null,"abstract":"Magnetic Resonance Imaging (MRI) scanners are widely used both for diagnostic purpose and in studies on material properties. As a consequence they play an important role in diagnosis of diseases and in materials investigations. MRI Quality assurance tests are mandatory to obtain and maintain optimal images during time, some institutional organizations have proposed requirements on MRI image quality even if there are no worldwide standardization procedures .The purpose of this study is to design a novel MRI phantom useful to evaluate basic image quality requirements: our phantom is designed, realized and tested in order to define specific image assurance protocols and tests. Moreover the developed device is low cost, reusable and can be filled with different MRI-compatible materials. In our application the phantom is filled with water and paraffin to compare contrast resolution and signal-to-noise ratio measurements for a same scanner. Tests have been performed on a 3T scanner with 7 different scansion settings. First experimental results are encouraging and confirm a previous theoretical investigation on the employed material characteristics. Therefore other tests and data are going to be collected for the future development and performance improvement of the device.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116618604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145215
Y. Li, Wei Liang, Jindong Tan, Yinlong Zhang
Despite recent advances, robust automatic segmentation for vertebrae computed tomography (CT) image still presents considerable challenges, mainly due to its inherent limitations, such as topological variation, irregular boundaries (double boundary, weak boundary) and image noises, etc. Therefore, this paper proposes a novel automatically initialized level set approach based on region correlation, which is able to deal with these problems in the segmentation. First, an automatically initialized level set function (AILSF) is designed to automatically generate a smooth initial contour. This AILSF comprises hybrid morphological filter (HMF) and Gaussian mixture model (GMM), which can guarantee the initial contour precisely adjacent to the object boundary. Second, we introduce a region correlation based level set formulation, which simultaneously consider the histogram information of inside and outside the level set contour, to overcome the weak boundary leaking and image noises problem. Experimental results on clinical lumbar vertebrae CT images demonstrate that our proposed approach is more accurate in segmenting with irregular boundaries and more robust to different levels of salt-and-pepper noises.
{"title":"A novel automatically initialized level set approach based on region correlation for lumbar vertebrae CT image segmentation","authors":"Y. Li, Wei Liang, Jindong Tan, Yinlong Zhang","doi":"10.1109/MeMeA.2015.7145215","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145215","url":null,"abstract":"Despite recent advances, robust automatic segmentation for vertebrae computed tomography (CT) image still presents considerable challenges, mainly due to its inherent limitations, such as topological variation, irregular boundaries (double boundary, weak boundary) and image noises, etc. Therefore, this paper proposes a novel automatically initialized level set approach based on region correlation, which is able to deal with these problems in the segmentation. First, an automatically initialized level set function (AILSF) is designed to automatically generate a smooth initial contour. This AILSF comprises hybrid morphological filter (HMF) and Gaussian mixture model (GMM), which can guarantee the initial contour precisely adjacent to the object boundary. Second, we introduce a region correlation based level set formulation, which simultaneously consider the histogram information of inside and outside the level set contour, to overcome the weak boundary leaking and image noises problem. Experimental results on clinical lumbar vertebrae CT images demonstrate that our proposed approach is more accurate in segmenting with irregular boundaries and more robust to different levels of salt-and-pepper noises.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"4 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113979338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145222
L. Iuppariello, P. Bifulco, M. Romano, M. Cesarelli, G. D'Addio
The segmentation of seemingly continuous movements into segments has been theorized for many years. These segments may be considered as “primitive” movements, or building blocks of more complex movements. The existence of these fragments, or sub-movements as they are called, has been supported by a wide range of studies over the past 100 years. Evidence for the existence of discrete sub-movements underlying continuous human movement has motivated many attempts to “extract” them. Recently, the sub-movement theory gained a great appeal in the rehabilitation field. In fact, understanding movement deficits following CNS lesions, and the relationships between these deficits and functional ability, is fundamental to the development of successful rehabilitation therapies. So, here a novel sub-movements decomposition method is proposed; it is based on a constrained-Expectation-Maximization. This representation allowed us to explore whether the movements are built up of elementary kinematic units by decomposing each signal into a weighted combination of 2D Gaussian functions. These can be used to assess the quality of reaching movements in subjects with Parkinson's Disease.
{"title":"Submovements composition and quality assessment of reaching movements in subjects with Parkinson's Disease","authors":"L. Iuppariello, P. Bifulco, M. Romano, M. Cesarelli, G. D'Addio","doi":"10.1109/MeMeA.2015.7145222","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145222","url":null,"abstract":"The segmentation of seemingly continuous movements into segments has been theorized for many years. These segments may be considered as “primitive” movements, or building blocks of more complex movements. The existence of these fragments, or sub-movements as they are called, has been supported by a wide range of studies over the past 100 years. Evidence for the existence of discrete sub-movements underlying continuous human movement has motivated many attempts to “extract” them. Recently, the sub-movement theory gained a great appeal in the rehabilitation field. In fact, understanding movement deficits following CNS lesions, and the relationships between these deficits and functional ability, is fundamental to the development of successful rehabilitation therapies. So, here a novel sub-movements decomposition method is proposed; it is based on a constrained-Expectation-Maximization. This representation allowed us to explore whether the movements are built up of elementary kinematic units by decomposing each signal into a weighted combination of 2D Gaussian functions. These can be used to assess the quality of reaching movements in subjects with Parkinson's Disease.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116822435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145267
Muhammad Naveed Tabassum, I. Elshafiey, Mubashir Alam
This paper proposes efficient algorithms to enhance the nearfield electromagnetic imaging of human head. Forward problem is modeled using SAM head phantom with brain tumor anomalies, surrounded by a circular applicator antenna array. Scattered signals are compressively sensed (CS) at a limited number of sensing positions, and the sensed signals are preprocessed efficiently using a proposed novel technique to maximize information extraction. A dictionary is formed and then implemented in CS based inverse problem analysis. Reconstructed images are enhanced using new post-processing techniques to improve the spatial resolution. Image quality is analyzed using the quality metric in terms of peak signal-to-noise ratio (PSNR). The quality of the reconstructed images and the corresponding PSNR values reveals the validity of the imaging techniques.
{"title":"Efficient techniques to enhance nearfield imaging of human head for anomaly detection","authors":"Muhammad Naveed Tabassum, I. Elshafiey, Mubashir Alam","doi":"10.1109/MeMeA.2015.7145267","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145267","url":null,"abstract":"This paper proposes efficient algorithms to enhance the nearfield electromagnetic imaging of human head. Forward problem is modeled using SAM head phantom with brain tumor anomalies, surrounded by a circular applicator antenna array. Scattered signals are compressively sensed (CS) at a limited number of sensing positions, and the sensed signals are preprocessed efficiently using a proposed novel technique to maximize information extraction. A dictionary is formed and then implemented in CS based inverse problem analysis. Reconstructed images are enhanced using new post-processing techniques to improve the spatial resolution. Image quality is analyzed using the quality metric in terms of peak signal-to-noise ratio (PSNR). The quality of the reconstructed images and the corresponding PSNR values reveals the validity of the imaging techniques.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116171149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145195
Giuseppe Cicotti, A. Coronato
Medical Devices (MDs) are subject to a Risk Management process to guarantee their safety with respect to risks patients and healthcare operators may experience. Well known classical Probabilistic Risk Assessment (PRA) techniques widely used in the MD sector, such as Failure Model and Effective Critical Analysis (FMEA) and Fault-Tree/Event-Tree do not allow to model the dynamics of hazardous situations which involves interactions among system components, human actions, process operations and the environment. This lack is overcome by using a dynamic PRA (DPRA) approach which aids in specifying risk scenarios. DPRA is extensively used in the nuclear, avionics, and space industries to identify possible accident scenarios, but to the best of our knowledge it is not so in the MD field. In this paper we propose a DPRA approach for MD Risk Assessment which relies on the use of a Probabilistic Model Checking (PMC) technique to perform quantitative analysis of risk scenarios. Particularly, our approach combines the ease of Event Sequence Diagram (ESD) to capture the dynamics of risk scenarios and the Markov Decision Processes formalism used as a stochastic model by which to encode ESD. By using a PMC technique to evaluate the MDP-based risk scenarios, we achieve two main benefits. Firstly, hundreds of different scenario realisations can be analysed in seconds due to the computational effectiveness of current PMC algorithms. Secondly, since such technique is based on a state-transition representation, we take advantage of the reachability analysis of states within the risk scenario state space to also quantify the effectiveness of control mechanisms or mitigation actions used to prevent and/or reduce the MD exposition to risk factors. Our ultimate objective is to derive an intuitive, easy, and computationally efficient formal method to perform quantitative risk scenario analysis oriented towards increasing the MD safety. We have applied our approach to an actual MD taken as a case study to demonstrate the features of our DPRA solution.
{"title":"Towards a Probabilistic Model Checking-based approach for Medical Device Risk Assessment","authors":"Giuseppe Cicotti, A. Coronato","doi":"10.1109/MeMeA.2015.7145195","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145195","url":null,"abstract":"Medical Devices (MDs) are subject to a Risk Management process to guarantee their safety with respect to risks patients and healthcare operators may experience. Well known classical Probabilistic Risk Assessment (PRA) techniques widely used in the MD sector, such as Failure Model and Effective Critical Analysis (FMEA) and Fault-Tree/Event-Tree do not allow to model the dynamics of hazardous situations which involves interactions among system components, human actions, process operations and the environment. This lack is overcome by using a dynamic PRA (DPRA) approach which aids in specifying risk scenarios. DPRA is extensively used in the nuclear, avionics, and space industries to identify possible accident scenarios, but to the best of our knowledge it is not so in the MD field. In this paper we propose a DPRA approach for MD Risk Assessment which relies on the use of a Probabilistic Model Checking (PMC) technique to perform quantitative analysis of risk scenarios. Particularly, our approach combines the ease of Event Sequence Diagram (ESD) to capture the dynamics of risk scenarios and the Markov Decision Processes formalism used as a stochastic model by which to encode ESD. By using a PMC technique to evaluate the MDP-based risk scenarios, we achieve two main benefits. Firstly, hundreds of different scenario realisations can be analysed in seconds due to the computational effectiveness of current PMC algorithms. Secondly, since such technique is based on a state-transition representation, we take advantage of the reachability analysis of states within the risk scenario state space to also quantify the effectiveness of control mechanisms or mitigation actions used to prevent and/or reduce the MD exposition to risk factors. Our ultimate objective is to derive an intuitive, easy, and computationally efficient formal method to perform quantitative risk scenario analysis oriented towards increasing the MD safety. We have applied our approach to an actual MD taken as a case study to demonstrate the features of our DPRA solution.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116199864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145237
R. Ciobanu, C. Schreiner, V. Drug, T. Schreiner, Dorin Antal
The lab-on-chip testing units based on microfluidics technology are booming nowadays, due to robustness, simplicity of use and reliability. Multilayer ceramics, functionalized with nano-scaled sensing materials, and further integrated within microfluidic test elements, are of great challenge and represent the purpose of the paper. The LTCC technology versatility allows the 3D integration of electrochemical sensors with microfluidic features, and further with advanced signal processing and wireless communication.
{"title":"Sensors in LTCC-technology with embedded microfluidic features, for medical applications","authors":"R. Ciobanu, C. Schreiner, V. Drug, T. Schreiner, Dorin Antal","doi":"10.1109/MeMeA.2015.7145237","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145237","url":null,"abstract":"The lab-on-chip testing units based on microfluidics technology are booming nowadays, due to robustness, simplicity of use and reliability. Multilayer ceramics, functionalized with nano-scaled sensing materials, and further integrated within microfluidic test elements, are of great challenge and represent the purpose of the paper. The LTCC technology versatility allows the 3D integration of electrochemical sensors with microfluidic features, and further with advanced signal processing and wireless communication.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127168727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MeMeA.2015.7145249
Manuel Schimmack, A. Hand, Paolo Mercorelli, A. Georgiadis
An orthosis embedded with a surface electromyography (sEMG) measurement system, integrated with metal-polymer composite fibers, was used to monitor the electrical activity of the forearm muscles during movement. The comfortable and noninvasive sEMG system was developed for long term monitoring during rehabilitation. Wavelets were used to denoise and compress the raw biosignals. The focus here is a comparison of the usefulness of the Haars and Daubechies wavelets in this process, using the Discrete Wavelet Transform (DWT) version of Wavelet Package Transform (WPT). A denoising algorithm is proposed to detect unavoidable measured noise in the acquired data, which uses a seminorm to define the noise. Using this norm it is possible to rearrange the wavelet basis, which can illuminate the differences between the coherent and incoherent parts of the sequence, where incoherent refers to the part of the signal that has either no information or contradictory information. In effect, the procedure looks for the subspace characterized either by small components or by opposing components in the wavelet domain. The proposed method is general, can be applied to any low frequency signal processing, and was built with wavelet algorithms from the WaveLab 850 library of the Stanford University (USA).
{"title":"Using a seminorm for wavelet denoising of sEMG signals for monitoring during rehabilitation with embedded orthosis system","authors":"Manuel Schimmack, A. Hand, Paolo Mercorelli, A. Georgiadis","doi":"10.1109/MeMeA.2015.7145249","DOIUrl":"https://doi.org/10.1109/MeMeA.2015.7145249","url":null,"abstract":"An orthosis embedded with a surface electromyography (sEMG) measurement system, integrated with metal-polymer composite fibers, was used to monitor the electrical activity of the forearm muscles during movement. The comfortable and noninvasive sEMG system was developed for long term monitoring during rehabilitation. Wavelets were used to denoise and compress the raw biosignals. The focus here is a comparison of the usefulness of the Haars and Daubechies wavelets in this process, using the Discrete Wavelet Transform (DWT) version of Wavelet Package Transform (WPT). A denoising algorithm is proposed to detect unavoidable measured noise in the acquired data, which uses a seminorm to define the noise. Using this norm it is possible to rearrange the wavelet basis, which can illuminate the differences between the coherent and incoherent parts of the sequence, where incoherent refers to the part of the signal that has either no information or contradictory information. In effect, the procedure looks for the subspace characterized either by small components or by opposing components in the wavelet domain. The proposed method is general, can be applied to any low frequency signal processing, and was built with wavelet algorithms from the WaveLab 850 library of the Stanford University (USA).","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125912074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-05-07DOI: 10.1109/MEMEA.2015.7145182
F. Palorini, D. Origgi, M. Guernieri, A. Troia, C. Magnetto, G. Durando
A framework for the evaluation of temperature increase in a tissue-mimicking material (TMM) induced by a clinical Ultrasound-guided High Intensity Focused Ultrasound (US-guided HIFU) system was developed. HIFU procedures are minimally invasive treatments that achieve deep tumor ablation, with the sparing of normal tissues, through thermal or mechanical effects induced by a HIFU beam generated with a focused transducer. Temperature evaluation is therefore crucial for the assurance of patient safety and treatment effectiveness. Nevertheless, it is a very difficult task on the US-guided systems, where high-pressure fields are involved. As far as we know, this study is the first attempt of temperature evaluation on a clinical US-guided HIFU system. Temperature evaluation was performed at typical clinical settings (between 80 W and 400 W, for 3s sonications) by the use of needle thermocouples connected to a voltmeter and inserted in a polyacrylamide gel phantom, prepared in-house to reproduce soft tissue behavior. Data sampling was performed with the use of acquisition software developed with LabView, while US-imaging was used to verify the position of the thermocouple. Typical rising curves of temperature were recovered, and rapid decrease was found when the HIFU field turned off. The highest temperature increases were concentrated inside the geometrical focus and were higher than 55 Celsius degrees at all power outputs. Repetition of measurements was not possible after sonications at the highest power outputs (400W). The absolute temperature of 98 Celsius degrees was never exceeded.
{"title":"Measurements of temperature increase induced on a tissue-mimicking material by a clinical US-guided HIFU system","authors":"F. Palorini, D. Origgi, M. Guernieri, A. Troia, C. Magnetto, G. Durando","doi":"10.1109/MEMEA.2015.7145182","DOIUrl":"https://doi.org/10.1109/MEMEA.2015.7145182","url":null,"abstract":"A framework for the evaluation of temperature increase in a tissue-mimicking material (TMM) induced by a clinical Ultrasound-guided High Intensity Focused Ultrasound (US-guided HIFU) system was developed. HIFU procedures are minimally invasive treatments that achieve deep tumor ablation, with the sparing of normal tissues, through thermal or mechanical effects induced by a HIFU beam generated with a focused transducer. Temperature evaluation is therefore crucial for the assurance of patient safety and treatment effectiveness. Nevertheless, it is a very difficult task on the US-guided systems, where high-pressure fields are involved. As far as we know, this study is the first attempt of temperature evaluation on a clinical US-guided HIFU system. Temperature evaluation was performed at typical clinical settings (between 80 W and 400 W, for 3s sonications) by the use of needle thermocouples connected to a voltmeter and inserted in a polyacrylamide gel phantom, prepared in-house to reproduce soft tissue behavior. Data sampling was performed with the use of acquisition software developed with LabView, while US-imaging was used to verify the position of the thermocouple. Typical rising curves of temperature were recovered, and rapid decrease was found when the HIFU field turned off. The highest temperature increases were concentrated inside the geometrical focus and were higher than 55 Celsius degrees at all power outputs. Repetition of measurements was not possible after sonications at the highest power outputs (400W). The absolute temperature of 98 Celsius degrees was never exceeded.","PeriodicalId":277757,"journal":{"name":"2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124781569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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