Coordination Chemistry Reviews最新文献_第5页

Nanozyme biosensing for food safety: New perspectives on classification, enzymatic activity, and sensing strategies 食品安全纳米酶生物传感：分类、酶活性和传感策略的新视角

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-06 DOI: 10.1016/j.ccr.2025.217464

Qilin Xu, Yong He, Xiaoli Li

As food safety issues have become increasingly prominent, the development of efficient and sensitive detection technologies to ensure food safety has become crucial. As an emerging class of biosensing materials, nanozymes have emerged as a pivotal tool in food safety detection, leveraging their exceptional catalytic activity and robust stability. This review systematically examines the classification of nanozymes based on material properties, along with internal and external factors influencing their activity. Moreover, the review elaborates on diverse biosensing strategies, encompassing single-mode, dual-mode, and multi-mode sensing approaches. These strategies significantly enhance detection sensitivity and accuracy by integrating complementary signal output modalities, enabling synergistic improvement in analytical performance. Notably, nanozyme-based biosensors exhibit broad application potential and distinct advantages in the realm of food safety detection, demonstrating versatility in addressing complex detection needs. Finally, this work summarizes current challenges in nanozyme biosensing technology, including inadequate biosafety assessment of nanozymes, interference from complex matrices, and limitations in achieving ultra-trace detection limits. It further puts forward prospective research directions and development prospects, offering novel perspectives and insights for advancing this interdisciplinary field.

随着食品安全问题的日益突出，开发高效灵敏的检测技术来确保食品安全变得至关重要。作为一类新兴的生物传感材料，纳米酶已成为食品安全检测的关键工具，利用其特殊的催化活性和强大的稳定性。本文系统地研究了纳米酶在材料性质上的分类，以及影响其活性的内部和外部因素。此外，本文还详细介绍了多种生物传感策略，包括单模、双模和多模传感方法。这些策略通过整合互补信号输出模式显著提高检测灵敏度和准确性，从而实现分析性能的协同改进。值得注意的是，基于纳米酶的生物传感器在食品安全检测领域显示出广泛的应用潜力和独特的优势，在解决复杂的检测需求方面显示出多功能性。最后，本文总结了当前纳米酶生物传感技术面临的挑战，包括纳米酶生物安全性评估的不足、复杂基质的干扰以及实现超痕量检测极限的局限性。进一步提出了前瞻性的研究方向和发展前景，为推动这一跨学科领域的发展提供了新的视角和见解。

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引用次数: 0

Host–guest chemistry in metal–organic frameworks: Interaction mechanisms, modulation strategies, and functional applications 金属有机框架中的主客体化学：相互作用机制、调制策略和功能应用

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-05 DOI: 10.1016/j.ccr.2025.217459

Cheng Yao , Junhua Wang , Wendi Yi , Jin Liu , Peng Chen , Yayun Zheng , Tancheng Xie , Haoqing Jiang , Hongxing Xu

Metal–organic frameworks (MOFs), as structurally programmable porous crystalline materials, offer a unique platform for modulating host–guest interactions with high spatial and chemical precision. These interactions govern molecular recognition, diffusion, and functional integration, underpinning diverse applications across energy, environmental, and biomedical systems. This review first delineates six fundamental types of host–guest interactions in MOFs, including electrostatic forces, hydrogen bonding, π–π stacking, van der Waals forces, coordination interactions, and confinement effects. Moreover, it discusses three principal strategies for engineering pore environments, including pore size modulation, surface functionalization, and dynamic framework regulation, with emphasis on their roles in modulating host–guest interactions. Additionally, it compares three encapsulation strategies, namely post-synthetic, in situ, and confinement-assisted methods, in terms of their influence on host–guest interactions. Finally, This review highlights recent advances in applying host–guest chemistry to catalysis, gas sorption, water recovery, energy systems, and biomedicine. Looking ahead, the integration of multiscale design, intelligent responsiveness, and multifunctional synergy is expected to drive the next generation of MOF-based host–guest systems toward practical deployment and transformative applications.

金属有机框架（mof）作为结构上可编程的多孔晶体材料，为具有高空间和化学精度的调制主客体相互作用提供了独特的平台。这些相互作用控制着分子识别、扩散和功能整合，支撑着能源、环境和生物医学系统的各种应用。本文首先概述了mof中主客体相互作用的六种基本类型，包括静电力、氢键、π -π堆叠、范德华力、配位相互作用和约束效应。此外，本文还讨论了工程孔隙环境的三种主要策略，包括孔径调节、表面功能化和动态框架调节，重点讨论了它们在调节主-客体相互作用中的作用。此外，它比较了三种封装策略，即合成后、原位和禁锢辅助方法，对主客体相互作用的影响。最后，本文综述了主客体化学在催化、气体吸附、水回收、能源系统和生物医学等方面的最新进展。展望未来，多尺度设计、智能响应和多功能协同的集成有望推动下一代基于mof的主客系统走向实际部署和变革性应用。

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引用次数: 0

Recent advances in coordination chemistry on the application and development of radiopharmaceuticals and boron neutron capture therapy 配位化学在放射性药物和硼中子俘获治疗中的应用与发展的最新进展

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-05 DOI: 10.1016/j.ccr.2025.217448

Jianghong Cai , Yinghuai Zhu , Xuanze Zhu , Narayan S. Hosmane , Qian Ding , Yizhun Zhu

The FDA approvals of [¹⁷⁷Lu]Lu-DOTATATE for neuroendocrine tumors and [¹⁷⁷Lu]Lu-PSMA-617 for metastatic castration-resistant prostate cancer signify the dawn of a transformative epoch in targeted radionuclide therapy. This review offers a systematic synthesis of cutting-edge advances in the development and application of coordination-based radiopharmaceuticals and boron neutron capture therapy (BNCT) agents. It presents a comprehensive overview of radionuclide classification (including α-, β-, and γ-emitters), along with chelator selection and the coordination chemistry of their metal complexes, while also detailing progress in the development of boron reagents, with particular emphasis on third-generation boron agents for BNCT and advanced boron delivery systems. Additionally, we highlight the emerging role of artificial intelligence in the coordinated radiopharmaceuticals and illustrate potential new AI directions in the field of BNCT. Finally, we address the principal challenges facing the field and explore possible solutions, aiming to inspire new research directions and accelerate the translation of these sophisticated technologies into more effective and precise cancer therapeutics. This review thereby, seeks to advance the application of coordination chemistry in precision medicine and to contribute meaningfully to improved human health outcomes.

FDA批准用于神经内分泌肿瘤的[177Lu]Lu-DOTATATE和用于转移性去势抵抗性前列腺癌的[177Lu]Lu-PSMA-617标志着靶向放射性核素治疗变革时代的到来。本文综述了基于配位的放射性药物和硼中子俘获治疗（BNCT）药物的开发和应用的最新进展。它全面概述了放射性核素的分类（包括α-， β-和γ-发射器），以及螯合剂的选择和它们的金属配合物的配位化学，同时也详细介绍了硼试剂的发展进展，特别强调了BNCT的第三代硼剂和先进的硼输送系统。此外，我们强调了人工智能在协调放射性药物中的新兴作用，并说明了BNCT领域潜在的新的人工智能方向。最后，我们讨论了该领域面临的主要挑战，并探索了可能的解决方案，旨在激发新的研究方向，并加速将这些复杂技术转化为更有效和精确的癌症治疗方法。因此，本综述旨在促进配位化学在精准医学中的应用，并为改善人类健康结果作出有意义的贡献。

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引用次数: 0

Pyroelectric and thermoelectric biomaterials and nanomedicine 热释电和热电生物材料和纳米医学

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-05 DOI: 10.1016/j.ccr.2025.217442

Shuangshuang Wang , Xiaoshuang Liu , Wei Feng , Xinyue Dai , Yu Chen

Advanced temperature-responsive materials, particularly pyroelectric and thermoelectric materials, are revolutionizing biomedical innovation due to their ability to generate electric charge in response to temperature fluctuations. These materials demonstrate remarkable capabilities in converting thermal energy into both electrical and chemical energy, thereby exhibiting exceptional catalytic properties. Their unique energy conversion and catalytic capabilities make them highly versatile in biomedical fields, with demonstrated potential in applications such as generators for implantable devices, biosensors, tumor therapy, and teeth whitening. A fundamental understanding of the distinct mechanisms underlying pyroelectric and thermoelectric effects, particularly their intrinsic charge generation processes and catalytic reaction principles, is crucial for advancing emerging trends in thermal-electric biomedical applications. This comprehensive review systematically summarizes and discusses recent progresses in the fabrication strategies of pyroelectric and thermoelectric materials, highlighting their transformative applications in biomedicine. Furthermore, it critically analyzes the current challenges and prospects of these thermal-responsive biomaterials, providing insights into their clinical translation potential. By exploring the intrinsic mechanisms of these two thermal-electric conversion materials, coupled with recent breakthroughs in advanced material fabrication techniques and artificial intelligence (AI)-driven high-throughput screening methodologies for performance optimization, pyroelectric and thermoelectric therapies will be poised to significantly benefit the human health in clinical settings.

先进的温度响应材料，特别是热释电和热电材料，由于它们能够响应温度波动产生电荷，正在彻底改变生物医学的创新。这些材料在将热能转化为电能和化学能方面表现出非凡的能力，从而表现出特殊的催化性能。其独特的能量转换和催化能力使其在生物医学领域用途广泛，在植入式装置、生物传感器、肿瘤治疗和牙齿美白等领域具有应用潜力。对热释电和热电效应的不同机制的基本理解，特别是其固有的电荷产生过程和催化反应原理，对于推进热电生物医学应用的新兴趋势至关重要。本文系统地总结和讨论了热释电和热电材料的制备策略的最新进展，重点介绍了它们在生物医学中的变革性应用。此外，它批判性地分析了这些热响应生物材料的当前挑战和前景，提供了对其临床转化潜力的见解。通过探索这两种热电转换材料的内在机制，再加上先进材料制造技术和人工智能（AI）驱动的高通量筛选方法的最新突破，热释电和热电疗法将在临床环境中显著造福人类健康。

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引用次数: 0

Nanozymes in respiratory medicine: From ultra-sensitive diagnostics to intelligent therapeutics 呼吸医学中的纳米酶：从超敏感诊断到智能治疗

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-04 DOI: 10.1016/j.ccr.2025.217387

Lianhua Liu , Xiaohua Yuan , Muhammad Idrees Khan , Qing Zhao , Imran Shakir , Xuping Sun , Fengming Luo

Respiratory diseases remain among the leading causes of morbidity and mortality worldwide, driven by oxidative stress, inflammation, and infection. Conventional enzyme therapies are limited by instability and high cost, whereas nanozymes, nanomaterials with enzyme-like catalytic activity, offer tunable, robust, and multifunctional alternatives. This review systematically summarizes recent advances in the coordination chemistry-driven design of nanozymes and their biomedical applications in respiratory medicine. Emphasis is placed on the catalytic mechanisms and structure-activity relationships underlying oxidoreductase-like nanozymes, followed by their roles in disease detection, redox regulation, and microenvironment remodeling across various respiratory pathologies including lung cancer, acute lung injury, pulmonary hypertension, etc. The review also highlights emerging strategies involving multi-enzyme cascade systems, biomimetic coatings, and artificial intelligence (AI)-assisted design to enhance specificity, biosafety, and translational potential. Finally, key challenges such as standardized activity evaluation, delivery through biological barriers, and long-term safety are discussed, together with perspectives on integrating AI, digital-twin modeling, and wearable diagnostics to establish an intelligent framework for catalytic medicine in the respiratory system.

由氧化应激、炎症和感染引起的呼吸系统疾病仍然是全世界发病率和死亡率的主要原因之一。传统的酶疗法受到不稳定性和高成本的限制，而纳米酶，具有酶样催化活性的纳米材料，提供了可调的，稳健的和多功能的替代品。本文系统地综述了纳米酶配位化学驱动设计及其在呼吸医学中的生物医学应用的最新进展。重点是氧化还原酶样纳米酶的催化机制和结构-活性关系，其次是它们在各种呼吸系统疾病（包括肺癌、急性肺损伤、肺动脉高压等）中的疾病检测、氧化还原调节和微环境重塑中的作用。该综述还强调了涉及多酶级联系统、仿生涂层和人工智能（AI）辅助设计的新兴策略，以提高特异性、生物安全性和转化潜力。最后，讨论了标准化活动评估、生物屏障递送和长期安全性等关键挑战，以及整合人工智能、数字孪生模型和可穿戴诊断的观点，以建立呼吸系统催化药物的智能框架。

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引用次数: 0

RIV-type AIEgens: progress, structures and functionalities riv型气囊：进展、结构和功能

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-04 DOI: 10.1016/j.ccr.2025.217446

Jia-Wen Tian , Xiao-Man Xu , Jun-Wei Zheng, Yuan-Yuan Liu, Kai Li, Shuang-Quan Zang

Aggregation-induced emission (AIE) is the photophysical phenomenon wherein molecules in an aggregated state express stronger emission compared to those in a dispersed state. The restriction of intramolecular vibration (RIV) is a crucial and widely acknowledged luminescence mechanism for the design of AIEgens. Despite its importance, AIE systems based on the RIV mechanism (RIV-type AIEgens) remain relatively scarce due to their multiple structures and complex synthesis methods. To date, comprehensive reviews focusing on RIV-type AIEgens are still lacking. In this article, we provide an overview of RIV-type AIEgens by first showcasing their development. Subsequently, the structures of RIV-type AIEgens have been devided into different types to interpret how the RIV mechanism works. Then the applications of RIV-type AIEgens are discussed. Finally, we address the challenges and opportunities involved in designing new RIV-type AIEgens with superior luminescent properties. We hope that this review will enhance the understanding of RIV-type AIEgens among non-specialists and young researchers, offer valuable insights into the relationship between their structural features and AIE properties, and promote further exploration into a variety of potential applications.

聚集诱导发射（AIE）是一种光物理现象，在这种现象中，处于聚集状态的分子比处于分散状态的分子发射更强。分子内振动（RIV）的限制是AIEgens设计中一个重要且被广泛认可的发光机制。尽管具有重要意义，但基于RIV机制的AIE体系（RIV型AIEgens）由于结构多样、合成方法复杂，仍然相对稀缺。迄今为止，仍缺乏针对riv型病原体的全面综述。在本文中，我们通过首先展示riv型aigens的发展来概述riv型aigens。随后，将RIV型抗原的结构划分为不同的类型，以解释RIV机制的工作原理。然后讨论了riv型aigens的应用。最后，我们讨论了设计具有优异发光性能的新型riv型AIEgens所面临的挑战和机遇。我们希望本文的综述能够加深非专业人士和年轻研究人员对riv型AIEgens的认识，为其结构特征与AIE性质之间的关系提供有价值的见解，并促进对各种潜在应用的进一步探索。

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引用次数: 0

Co-based bifunctional OER/ORR Electrocatalysts: From nanostructure engineering to catalytic mechanism innovation for cutting-edge research in empowering energy conversion systems 共基双功能OER/ORR电催化剂：从纳米结构工程到催化机制创新，为增强能量转换系统的前沿研究

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-04 DOI: 10.1016/j.ccr.2025.217393

Chaojie Lyu , Jiaxin Yang , Hanyu Guo , Jiarun Cheng , Dongsheng Geng , Yiming Liu

The focal point of new energy research lies in the advancement of novel energy conversion and storage apparatus. The oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) serve as two fundamental processes in energy conversion systems. In the process of catalytic reaction, the reactants need to diffuse to the surface of the catalyst to carry out the reaction, including mass transfer, adsorption, desorption and other processes between the two-phase interface. This is also the main reason for the slow kinetics of ORR and OER. Cobalt (Co)-based materials stand out as a prime alternative to traditional precious metal catalysts, owing to their earth-abundance, excellent electronic effects and controllability of structure and morphology. This review focuses on the structural configuration, synthesis methodologies, and emerging applications of Co-based bifunctional electrocatalysts, and investigates their catalytic performances in ORR/OER reactions within alkaline electrolytes. Firstly, by analyzing the catalytic traits and potential reaction routes of ORR/OER, the main reaction mechanisms of both are elaborated respectively. Secondly, the synthesis strategies, activity enhancement mechanisms, and electrocatalytic performances of Co-based electrocatalysts containing Co-based oxides, Co-based phosphides, Co-based sulfides, Co-N-C materials, and Co-based single atoms are emphasized. Moreover, the applications of these catalysts in ORR/OER bifunctional electrocatalysis are investigated. Finally, we focus on the strategies and application prospects of Co-based bifunctional electrocatalysts in the rapidly growing field, as well as facing the challenges and opportunities in the future. This review is expected to provide a reference for peer researchers in designing and developing the next-generation bifunctional ORR/OER electrocatalysts with better activity and long-term stability.

新能源研究的重点在于新型能量转换和存储装置的研制。析氧反应（OER）和氧还原反应（ORR）是能量转换系统中的两个基本过程。在催化反应过程中，反应物需要扩散到催化剂表面才能进行反应，包括两相界面之间的传质、吸附、解吸等过程。这也是造成ORR和OER动力学缓慢的主要原因。钴基材料因其丰富的地球资源、优异的电子效应以及结构和形态的可控性而成为传统贵金属催化剂的主要替代品。本文综述了钴基双功能电催化剂的结构构型、合成方法和新应用，并对其在碱性电解质中ORR/OER反应中的催化性能进行了研究。首先，通过分析ORR/OER的催化特性和潜在反应途径，分别阐述了两者的主要反应机理。其次，重点介绍了含co基氧化物、co基磷化物、co基硫化物、Co-N-C材料和co基单原子的co基电催化剂的合成策略、活性增强机理和电催化性能。并对这些催化剂在ORR/OER双功能电催化中的应用进行了研究。最后，重点讨论了钴基双功能电催化剂在这一快速发展领域的策略和应用前景，以及未来面临的挑战和机遇。本文的研究成果有望为同行设计和开发具有更好活性和长期稳定性的下一代双功能ORR/OER电催化剂提供参考。

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引用次数: 0

Coordination nanoarchitectonics with synergistic X-ray photonics: coupled photochromism and luminescence modulation for intelligent radiation-responsive materials 协同x射线光子学的配位纳米结构：智能辐射响应材料的耦合光致变色和发光调制

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-03 DOI: 10.1016/j.ccr.2025.217443

Xue Bai , Jiayan Liao , Yueteng Zhang , Zan Xu , Yingzhu Zi , Heping Zhao , Anjun Huang , Zhiguo Song , Jianbei Qiu , Jean-Claude G. Bünzli , Zhengwen Yang

X-ray-induced photochromism (X-PC) represents an emerging paradigm in radiation-responsive photonics, enabling deep-penetrating and reversible optical modulation far beyond the limitations of conventional light-driven photochromism. This review highlights the coupling between X-PC and luminescence modulation in inorganic systems as a transformative strategy within the framework of coordination nanoarchitectonics, enabling the rational design of intelligent, multi-signal X-ray photonic systems. We first elucidate the fundamental mechanisms in which X-ray excitation triggers core-electron ionization, defect generation, and valence transitions that dynamically regulate two optical outputs—coloration and emission. The cooperative interplay among defect engineering and valence-state dynamics is systematically discussed to reveal how carrier migration and trap distributions govern both photochromic reversibility and luminescence tunability. Building on this mechanistic foundation, we summarize design strategies that integrate dopant chemistry and defect modulation to achieve precise control over X-ray-induced carrier dynamics, energy transfer, and emission modulation. Finally, we highlight key breakthroughs in dual-mode X-ray imaging, rewritable optical storage, and time-gated anti-counterfeiting, alongside emerging directions toward flexible and biomedical platforms. By framing these advances, this review establishes a unified framework for adaptive X-ray photonics, connecting fundamental atomic-scale processes with next-generation materials for diagnostics, information security, and radiation safety.

x射线诱导光致变色（X-PC）代表了辐射响应光子学的一个新兴范例，它使深穿透和可逆的光调制远远超出了传统光驱动光致变色的限制。这篇综述强调了无机系统中X-PC和发光调制之间的耦合作为配位纳米结构框架内的一种变革策略，使智能多信号x射线光子系统的合理设计成为可能。我们首先阐明了x射线激发触发核心电子电离、缺陷产生和价态跃迁的基本机制，这些跃迁动态地调节了两种光输出——着色和发射。系统地讨论了缺陷工程和价态动力学之间的相互作用，揭示了载流子迁移和陷阱分布如何控制光致变色可逆性和发光可调性。在此机制基础上，我们总结了集成掺杂化学和缺陷调制的设计策略，以实现对x射线诱导载流子动力学，能量转移和发射调制的精确控制。最后，我们强调了双模x射线成像，可重写光存储和时间门控防伪方面的关键突破，以及柔性和生物医学平台的新兴方向。通过概述这些进展，本综述建立了自适应x射线光子学的统一框架，将基本原子尺度过程与用于诊断、信息安全和辐射安全的下一代材料联系起来。

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引用次数: 0

Exploring the potential of cobalt ferrite and its nanocomposites in photocatalytic wastewater treatment 探讨铁酸钴及其纳米复合材料在光催化废水处理中的潜力

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-03 DOI: 10.1016/j.ccr.2025.217440

Chinmay , Simranjeet Singh , Yogita , Mohd Jamshaiya Raza , Rajni , Vishaka Chauhan , Anjaneyulu Bendi , Ravi Tomar

Nowadays, the global economy has undergone significant improvement due to the Industrial Revolution; however, industrial waste is a major contributor to severe environmental pollution. The contamination of water bodies by the release of industrial effluent carrying harmful dyes is a significant concern for the scientific community. In this regard, the development of several cutting-edge materials and methods is necessary for effective dye degradation to address this problem. Currently, researchers have focused on utilizing a variety of nanomaterials in wastewater purification, with special reference to dye degradation. Among the various nanomaterials, CoFe₂O₄ nanoparticles and their nanocomposites have garnered significant attention due to their distinct magnetic, structural, and catalytic properties, as well as their chemical stability, high surface area, and excellent reusability in the removal of dyes from wastewater. This review aims to explore recent advancements in the applications of CoFe₂O₄ nanomaterials in wastewater treatment, with a special focus on photocatalytic degradation of dyes. The study focuses on the chemistry of 19 different CoFe₂O₄ nanoparticles with varying sizes for the degradation of 19 dyes, as well as 77 distinct cobalt ferrite nanocomposites for the degradation of 47 different dyes from wastewater. The findings prove that CoFe₂O₄ nanomaterials are potential candidates for the treatment of dye-contaminated wastewater. Considering the perspective of sustainable development, the scientific community needs to focus on exploring the chemistry of biosynthesized CoFe₂O₄ nanomaterials for the degradation of dyes from wastewater.

如今，由于工业革命，全球经济得到了显著改善；然而，工业废物是造成严重环境污染的主要因素。含有有害染料的工业废水对水体的污染是科学界关注的一个重大问题。在这方面，开发一些前沿材料和方法是有效降解染料的必要条件。目前，研究人员已将各种纳米材料用于废水净化，特别是染料降解。在各种纳米材料中，CoFe2O4纳米粒子及其纳米复合材料因其独特的磁性、结构和催化性能，以及化学稳定性、高表面积和在废水中去除染料方面的优异可重复使用性而备受关注。本文综述了CoFe2O4纳米材料在废水处理中的应用进展，重点介绍了其光催化降解染料的研究进展。该研究重点研究了19种不同尺寸的CoFe2O4纳米颗粒降解19种染料的化学性质，以及77种不同的钴铁氧体纳米复合材料降解废水中的47种不同染料的化学性质。研究结果表明，CoFe2O4纳米材料是处理染料污染废水的潜在候选材料。从可持续发展的角度考虑，科学界需要重点探索生物合成CoFe2O4纳米材料的化学性质，以降解废水中的染料。

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引用次数: 0

Advances in sensing mechanisms of porous framework-based exhaled gas sensors for healthcare 基于多孔框架的医疗用呼出气体传感器传感机制研究进展

IF 23.5 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews

Pub Date : 2025-12-02 DOI: 10.1016/j.ccr.2025.217452

Xinyu Lu , Menghao Xu , Xiaoyue Yu , Yuan Zhong , Tianxiang Wei , Zhihui Dai

Exhaled gas analysis has emerged as a powerful, non-invasive tool for clinical diagnosis and health monitoring, accelerating the demand for high-performance detection technologies. Sensors based on porous framework materials (PFMs) have shown exceptional promise in this field, offering significant advantages in portability, real-time response, and room-temperature operation. The core of their functionality lies in the sensing mechanisms, which directly determine device sensitivity, selectivity, and stability. This review systematically summarizes and elucidates the fundamental sensing mechanisms of PFM-based exhaled gas sensors, with a dedicated focus on their structure-property-performance relationships. We first introduce major exhaled biomarkers and their clinical significance. The main body is then devoted to a mechanistic classification and in-depth discussion of recognition, transduction, and signal output processes, highlighting how specific structural features, such as tunable porosity, surface functionality, and coordination environments, govern the sensing performance through various mechanisms including adsorption-diffusion, charge transfer, and molecular recognition. Furthermore, we explore how these mechanisms enable the detection of biomarkers associated with diseases such as diabetes, asthma, renal dysfunction, and pulmonary cancers. Finally, we address current challenges and future research directions aimed at mechanistic innovation and material design. This review provides a mechanistic foundation and offers advanced insights for developing next-generation PFM-based gas sensors for practical healthcare applications.

呼气分析已成为临床诊断和健康监测的一种强大的非侵入性工具，加速了对高性能检测技术的需求。基于多孔框架材料（pfm）的传感器在这一领域表现出了非凡的前景，在便携性、实时响应和室温操作方面具有显著优势。其功能的核心在于传感机制，直接决定了器件的灵敏度、选择性和稳定性。本文系统地总结和阐述了基于pfm的呼出气体传感器的基本传感机制，重点介绍了它们的结构-性能-性能关系。我们首先介绍主要的呼气生物标志物及其临床意义。然后，主体致力于识别、转导和信号输出过程的机制分类和深入讨论，强调特定的结构特征，如可调孔隙度、表面功能和协调环境，如何通过各种机制（包括吸附-扩散、电荷转移和分子识别）控制传感性能。此外，我们探讨了这些机制如何能够检测与糖尿病、哮喘、肾功能障碍和肺癌等疾病相关的生物标志物。最后，我们提出了当前面临的挑战和未来的研究方向，旨在机械创新和材料设计。这篇综述为开发用于实际医疗保健应用的下一代基于pfm的气体传感器提供了机制基础和先进见解。

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引用次数: 0