Coordination Chemistry Reviews最新文献

Nanomaterials have become promising tools in cancer therapy due to their unique physicochemical properties and wide range of applications. Among various nanomaterials, tin-based nanomaterials have attracted much attention for their potential in treating malignant tumors. The presence of multivalent ions gives tin-based nanomaterials multiple enzymatic activities. Attributed to the quantum-confinement effect, tin-based nanomaterials have a strong light-absorption ability and can efficiently convert light energy into heat energy. The low bandgap value enables the tin-based nanomaterials to realize the separation of electron-hole pairs and mediate the enzymatic therapy under the excitation of near-infrared laser and ultrasound. On the basis of this, tin-based nanoparticles mediate the process of anti-tumor immune response by inducing immunogenic cell death in tumor cells. Herein, we provide a comprehensive overview of tin-based nanomaterials with the morphology of nanoparticles, nanorods, lamellae, mesoporous nanoparticles, and tin-based composite nanomaterials for cancer therapy. The effectiveness, safety, and limitations of these nanomaterials are discussed based on the reported studies. In addition, this review discusses the challenges and prospects for the further development and clinical translation of tin-based nanomaterials in the treatment of malignant tumors. In conclusion, this review aims to deepen our understanding of the important role of tin-based nanomaterials in oncology and provide guidance for future research in this field.

The G-quadruplex (G4) represents a noncanonical guanine-rich nucleic acid secondary structure characterized by the presence of two or more G-quartets stabilized through Hoogsteen hydrogen bonding. These structures play essential roles in various biological processes including DNA replication, gene expression regulation, telomere maintenance, and genomic stability. Effectively visualizing and precisely detecting G4 structures and their dynamic changes in cells and in vivo are crucial for elucidating the relationship between different G4 structures and functions within complex biological systems. Among the plethora of G4 probes studied, near-infrared (NIR) G4 fluorescent probes are highly sought after due to their minimal autofluorescence and low cellular damage. The significance of NIR G4 fluorescent probes lies in their application for in-depth imaging and in vivo studies, providing excellent resolution with minimal perturbation of the organisms. This review comprehensively examines recent advancements of NIR G4 fluorescent probes for in vitro, cellular, and in vivo imaging, considering various G4 molecular backbones. The discussion encompasses the photophysical properties, binding affinity to G4, molecular design strategies, and modification concepts of NIR G4 fluorescent probes. Finally, this review is designed on the existing challenges and future development potential of G4 imaging tools.

Electrochemiluminescence (ECL) is a technique that integrates the benefits of both chemiluminescence and electrochemistry. Early illness diagnosis and hazardous material detection have both benefited greatly from its benefits, which include minimal background signal, high sensitivity, and easy operation. A novel class of porous materials known as metal-organic frameworks (MOFs) is created when organic ligands and inorganic metal nodes self-assemble. Its enormous specific surface area, many functionalized sites, adaptable structure, and range of applications in biomedicine, biosensing, and other domains have made it a hot topic in chemical and biological research. This article examines the development of MOF applications in recent years pertaining to the production of electrochemiluminescence biosensors. First, the effects of metal ions on aggregation induced electrochemiluminescence are analyzed, and design approaches for meeting the needs of ECL applications are discussed. The applications of MOFs are then categorized and described based on three factors: electroactivity, catalytically active chemicals, and carriers, in accordance with the many roles of MOFs in ECL. Lastly, present problems and obstacles are examined, and potential future routes for growth are suggested.

Nanozymes are a type of nanomaterials that mimics natural enzymes with biocatalytic functions. Oxidase is a kind of oxidoreductase which oxidizes hydrogen donor substrates in the presence of molecular oxygen. Recently, there have been many reports on various nanomaterials exhibiting oxidase-mimicking activity, which currently became one of the most extensively studied enzymatic property with broad applications. Considering the significant advances and superior prospects of oxidase mimics, this review categorizes oxidase mimicking nanozymes based on their substrates and brief introduction of their syntheses. Further their sensing applications along with the possible catalytic mechanisms are systematically and comprehensively overviewed and discussed. Eventually, the possible opportunities and challenges in the future to explore oxidase mimics for applications in sensing or analytical chemistry are prospected.

Ferrite nanomaterials (FNMs) have gained much attention due to their vast applications in several areas, such as wastewater treatment, electronics, magnetic, catalysts, biomedical, microwave absorbers, sensors, and biosensors. This review focuses on the synthesis of FNMs and illustrates the advantages and disadvantages of commonly used synthesis techniques, emphasizing the recently published works. The main purpose of this review is to study the different synthesis techniques of FNMs, which are cost-effective and environment-friendly, and how these approaches help obtain nanomaterials with the required morphology and structure for specific applications including electronic, magnetic and sensor applications. In addition to the synthesis, FNMs must be characterized to evaluate their properties. In this study, Bottom-up and Top-down routes of synthesizing nanostructured materials are compared, analyzed, and reviewed. This review outlines the synthesis methodologies for FNMs tailored to specific applications, the common characterization techniques, and the key computational studies using both classical and quantum methods.

Research on nano-armored bacterial materials (NABM) has attracted considerable attention because of their ability to exert synergistic effects on bacteria and nanomaterials through rational material design. Currently, the predominant methods for preparing NABM involve covalent interactions, supramolecular interactions, and physical encapsulation. Among these mechanisms, supramolecular interaction-based NABM presents remarkable advantages, including mild reaction conditions, reversibility, and exceptional selectivity. In this review, we systematically introduce various NABM based on supramolecular interactions, such as electrostatic interactions, hydrogen bonding, host-guest interactions, and streptavidin-biotin interactions. Additionally, we summarize the biomedical applications of these composite materials in tumor therapy and inflammatory bowel disease and others. Finally, we discuss the prospects for clinical applications and the challenges in the future development of supramolecular interaction-based NABM. This review offers a comprehensive overview of the construction methods and biomedical applications of NABM utilizing supramolecular interactions. This study provides significant reference value for the development of next-generation bioactive materials.

Developing highly active and stable electrocatalysts is significant for generating green energy. Ultrahigh exposed active atoms, tunable electronic properties, and high charge migration rate offer a substantial scope of two-dimensional (2D) materials as advanced electrocatalysts but still face limited intrinsic activities and poor stability. Confining metal or non-metal atoms in 2D materials has recently expressed high activity and stability due to the regulated electronic structure. In this review, based on the analysis of the structure of 2D materials, we systematically summarize and elucidate the scientific essence of improved electrocatalysis activity by confining atoms. First, we introduce the favorable structure of 2D single-element and compound materials for electrocatalysis. Then, recent progress in intrinsic and interface structure regulation of modified 2D material by coordination- and substitution-confinement is comprehensively reviewed with a special focus on the advances in interface structure regulation by metal atoms confinement. Finally, future research directions and opportunities for developing more advanced 2D confinement material for electrocatalysis are proposed. This review offers some guidance in the rational construction of efficient 2D materials by atom confinement for meeting the high demands in electrocatalysts.

Capacitive deionization (CDI) offers an appealing electrochemical solution for water treatment, where electrode materials play a crucial role in ensuring the efficiency of CDI devices. The quest for novel electrode materials is driven by the need to enhance desalination capacity, cycling stability, ion selectivity, and energy efficiency, given that traditional carbon materials relying on electric double layer electrosorption principle often exhibit subpar desalination capabilities. Among the standout options, Prussian blue (Fe₄[Fe(CN)₆]₃) and its analogs (PB/PBAs) have stood out in CDI systems due to their superior performance and durability as coordination polymers. Nevertheless, challenges persist in leveraging their full potential for CDI, stemming from issues like low desalination capacity, slow kinetics, poor conductivity, structural vulnerability, and limited electrochemical activity. Recent years have witnessed the emergence of innovative strategies aimed at addressing these obstacles, particularly through advancements in structural and compositional manipulation. This review seeks to consolidate the latest advancements in the nanoarchitectonics of PB/PBAs, exploring their classification, and synthesis methodologies, and delving into the fundamental principles governing their utility in CDI applications—anchored in considerations of thermodynamics, kinetics, and mechanisms. Notably, the review underscores the prevailing challenges faced by PB/PBAs in CDI deployment, prompting the discussion of proactive approaches to guide future material innovation and usage. By shedding light on the ongoing efforts to enhance PB/PBAs for CDI, this review anticipates that advancements in nanoarchitectonics will unlock fresh possibilities in the realm of high-performance CDI material design and implementation.

The present review critically observes literature data on stability constants of gold(I) and gold(III) complexes in aqueous and non-aqueous medium. The equilibrium constants of complexation or ligand exchange as well as the values of E⁰ for the redox processes [Au⁺³L_x]^z± + 3e = Au + xL^(−3±z)/x and [Au⁺¹L_x]^z± + e = Au + xL^(−1±z)/x are reported or calculated using the results of other researchers. Information about the composition and stability of the products formed by gold species with macrobiomolecules such as proteins and DNA is provided. When analyzing an interaction between a gold complex and biomolecule, several competing processes should be taken into account, including equilibria of ligand exchange, hydrolysis of gold complex, and binding of gold or free ligand to protein or DNA. The review aims to help those who develop new gold-based drugs and might be of interest to specialists in gold chemistry.

The pursuit of more sensitive, selective, multifunctional, portable and cost-effective diagnostic tools has propelled biosensing technology to the forefront of clinical research. Surface plasmon resonance (SPR) biosensors could achieve label-free, sensitive, real-time monitoring of biomolecular interactions, thus providing a suitable and reliable platform for clinical analysis. However, to maximize their effectiveness in clinical settings, several challenges need to be addressed: i) improving sensitivity to detect low levels of analytes, ii) enhancing specificity for accurate analysis in complex biological fluids, iii) enabling detection of multiple analytes, iv) making portable configurations for point-of-care testing, and v) increasing surface renewability and sensor stability for long-term economical use. Despite numerous reviews, this review aims to comprehensively collate and evaluate the advancements made in the last decade to tackle each challenge of SPR sensors for clinical analysis individually, including novel signal amplification methods, antifouling interface, multiple detection, miniaturized SPR systems, regeneration techniques, and stability enhancement methods. Together, these enhancements are transforming SPR biosensors into powerful tools for clinical diagnostics.