Pub Date : 2023-09-08DOI: 10.21070/acopen.8.2023.7848
Fityan Izza Noor Abidin, Sri Enggar Puji Handayani, Sarwendah Biduri
This study explores the impact of individual morality and internal controls on fraud risk in the implementation of healthcare assurance by Indonesia's BPJS. It emphasizes the moderating role of organizational ethics. Using a quantitative approach and Partial Least Square (PLS) analysis, data was gathered via direct surveys from Rumah Sakit Umum Al-Islam H.M. Mawardi Krian employees. The results indicate that individual morality has a limited effect on fraud risk, with individual moral reasoning playing a key role in behavior. However, internal controls significantly mitigate fraud risk, aligning with the fraud triangle theory's principles. Surprisingly, organizational ethical culture weakens the link between individual morality and internal control in relation to fraud risk, as a strong ethical culture raises standards and influences employee conduct positively. In conclusion, the study highlights the importance of strengthening internal controls in healthcare institutions to enhance employee ethics and prevent fraud. Future research could extend this investigation to include manufacturing companies, broadening our understanding of factors mitigating fraud risk in BPJS healthcare assurance. Involving multiple healthcare institutions would enhance the generalizability of these findings. highlights : Individual moral reasoning levels do not significantly impact fraud risk in healthcare assurance implementation, emphasizing the complexity of ethical decision-making. Effective internal controls are crucial in mitigating fraudulent activities, aligning with the principles of the fraud triangle theory. Organizational ethical culture can either strengthen or weaken the relationship between individual morality and internal control, highlighting the role of corporate ethics in shaping employee behavior and reducing fraud risk. Keywords : Individual Morality, Internal Control, Organizational Ethics, Fraud Risk, Healthcare Assurance
本研究探讨了印度尼西亚 BPJS 在实施医疗保障过程中，个人道德和内部控制对欺诈风险的影响。研究强调了组织道德的调节作用。研究采用定量方法和偏最小二乘法（PLS）分析，通过对 Rumah Sakit Umum Al-Islam H.M. Mawardi Krian 员工的直接调查收集数据。结果表明，个人道德对欺诈风险的影响有限，个人道德推理在行为中起着关键作用。然而，内部控制却大大降低了欺诈风险，符合欺诈三角理论的原则。令人惊讶的是，组织道德文化削弱了个人道德与内部控制在欺诈风险方面的联系，因为强大的道德文化会提高标准，对员工行为产生积极影响。总之，本研究强调了医疗机构加强内部控制以提高员工道德水平和预防欺诈的重要性。未来的研究可以将这项调查扩展到制造企业，从而拓宽我们对减轻 BPJS 医疗保证中欺诈风险因素的理解。让多家医疗机构参与进来将增强这些研究结果的普遍性。 亮点：个人道德推理水平对医疗保证实施过程中的欺诈风险没有显著影响，这强调了道德决策的复杂性。 有效的内部控制对于减少欺诈活动至关重要，这与欺诈三角理论的原则相一致。 组织道德文化既可以加强也可以削弱个人道德与内部控制之间的关系，突出了企业道德在塑造员工行为和降低欺诈风险方面的作用。 关键词：个人道德；内部控制；组织伦理；欺诈风险；医疗保障
{"title":"Individual Morality, Internal Control Of Fraud With Organization Ethical Culture As Moderation","authors":"Fityan Izza Noor Abidin, Sri Enggar Puji Handayani, Sarwendah Biduri","doi":"10.21070/acopen.8.2023.7848","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7848","url":null,"abstract":"This study explores the impact of individual morality and internal controls on fraud risk in the implementation of healthcare assurance by Indonesia's BPJS. It emphasizes the moderating role of organizational ethics. Using a quantitative approach and Partial Least Square (PLS) analysis, data was gathered via direct surveys from Rumah Sakit Umum Al-Islam H.M. Mawardi Krian employees. The results indicate that individual morality has a limited effect on fraud risk, with individual moral reasoning playing a key role in behavior. However, internal controls significantly mitigate fraud risk, aligning with the fraud triangle theory's principles. Surprisingly, organizational ethical culture weakens the link between individual morality and internal control in relation to fraud risk, as a strong ethical culture raises standards and influences employee conduct positively. In conclusion, the study highlights the importance of strengthening internal controls in healthcare institutions to enhance employee ethics and prevent fraud. Future research could extend this investigation to include manufacturing companies, broadening our understanding of factors mitigating fraud risk in BPJS healthcare assurance. Involving multiple healthcare institutions would enhance the generalizability of these findings. highlights : Individual moral reasoning levels do not significantly impact fraud risk in healthcare assurance implementation, emphasizing the complexity of ethical decision-making. Effective internal controls are crucial in mitigating fraudulent activities, aligning with the principles of the fraud triangle theory. Organizational ethical culture can either strengthen or weaken the relationship between individual morality and internal control, highlighting the role of corporate ethics in shaping employee behavior and reducing fraud risk. Keywords : Individual Morality, Internal Control, Organizational Ethics, Fraud Risk, Healthcare Assurance","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-08DOI: 10.21070/acopen.8.2023.7877
Ali Sadie Alhashemi, Hasanain Abdul-Muhsin, Ahmed Amer Abdul Hussein
This study aims to investigate the frequency and potential causes of gastrointestinal bleeding (GIB) in Intensive Care Units (ICUs) while focusing on the associated risk factors. Conducted as a cohort study in critical care centers at Ghazi AL Hariri Teaching Hospital for Special Surgeries and Burn Specialty Teaching Hospital at Medical City Complex in Baghdad, Iraq, spanning from 2018 to 2022, the research analyzed patients with clinically significant GIB upon admission to the ICU using univariate and multivariate intervention analyses. The key findings revealed that 1.3% of ICU cases developed GIB without prior symptoms, with risk factors including prolonged ICU stays, elevated creatinine levels, elevated bilirubin, and heightened Aspartate Aminotransferase activity. Alarmingly, 47% of GIB-diagnosed ICU patients faced mortality during their hospitalization, significantly higher than non-GIB patients (30%). This study underscores the importance of vigilance and early detection for high-risk patients, given the significant morbidity and mortality associated with GIB in the ICU population, despite its declining incidence. Highlights : This cohort study investigates the frequency and risk factors associated with gastrointestinal bleeding (GIB) in ICU patients. Prolonged ICU stays, elevated creatinine and bilirubin levels, and increased Aspartate Aminotransferase activity are identified as risk factors for GIB development. Alarmingly, GIB-diagnosed ICU patients have a significantly higher mortality rate (47%) compared to non-GIB patients (30%), highlighting the critical importance of early detection and vigilance in managing this condition. Keywords: Gastrointestinal Bleeding, Intensive Care Units, Risk Factors, Mortality, Cohort Study
本研究旨在调查重症监护病房（ICU）中消化道出血（GIB）的频率和潜在原因，同时关注相关的风险因素。研究以队列研究的形式在伊拉克巴格达加齐-哈里里特殊外科教学医院（Ghazi AL Hariri Teaching Hospital for Special Surgeries）和医疗城综合体烧伤专科教学医院（Burn Specialty Teaching Hospital at Medical City Complex）的重症监护中心进行，时间跨度为2018年至2022年，研究采用单变量和多变量干预分析方法对重症监护病房入院时出现临床意义明显的胃肠道出血的患者进行了分析。主要研究结果显示，1.3%的重症监护病房病例在之前没有症状的情况下发生了GIB，风险因素包括重症监护病房住院时间延长、肌酐水平升高、胆红素升高和天冬氨酸氨基转移酶活性升高。令人担忧的是，47% 的确诊 GIB ICU 患者在住院期间面临死亡，明显高于非 GIB 患者（30%）。这项研究强调了对高危患者保持警惕和早期发现的重要性，因为尽管GIB的发病率在下降，但ICU人群中GIB的发病率和死亡率却很高。 亮点：这项队列研究调查了 ICU 患者消化道出血（GIB）的频率和相关风险因素。 研究发现，ICU 病程延长、肌酐和胆红素水平升高以及天冬氨酸氨基转移酶活性升高是 GIB 发生的风险因素。 令人担忧的是，确诊为 GIB 的 ICU 患者的死亡率（47%）明显高于未确诊为 GIB 的患者（30%），这凸显了早期发现和警惕这种疾病的重要性。 关键词：胃肠道出血胃肠道出血 重症监护病房 风险因素 死亡率 队列研究
{"title":"Incidence and Risk Factors of Gastrointestinal Bleeding in ICU Patients: A Four-Year Cohort Study","authors":"Ali Sadie Alhashemi, Hasanain Abdul-Muhsin, Ahmed Amer Abdul Hussein","doi":"10.21070/acopen.8.2023.7877","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7877","url":null,"abstract":"This study aims to investigate the frequency and potential causes of gastrointestinal bleeding (GIB) in Intensive Care Units (ICUs) while focusing on the associated risk factors. Conducted as a cohort study in critical care centers at Ghazi AL Hariri Teaching Hospital for Special Surgeries and Burn Specialty Teaching Hospital at Medical City Complex in Baghdad, Iraq, spanning from 2018 to 2022, the research analyzed patients with clinically significant GIB upon admission to the ICU using univariate and multivariate intervention analyses. The key findings revealed that 1.3% of ICU cases developed GIB without prior symptoms, with risk factors including prolonged ICU stays, elevated creatinine levels, elevated bilirubin, and heightened Aspartate Aminotransferase activity. Alarmingly, 47% of GIB-diagnosed ICU patients faced mortality during their hospitalization, significantly higher than non-GIB patients (30%). This study underscores the importance of vigilance and early detection for high-risk patients, given the significant morbidity and mortality associated with GIB in the ICU population, despite its declining incidence. Highlights : This cohort study investigates the frequency and risk factors associated with gastrointestinal bleeding (GIB) in ICU patients. Prolonged ICU stays, elevated creatinine and bilirubin levels, and increased Aspartate Aminotransferase activity are identified as risk factors for GIB development. Alarmingly, GIB-diagnosed ICU patients have a significantly higher mortality rate (47%) compared to non-GIB patients (30%), highlighting the critical importance of early detection and vigilance in managing this condition. Keywords: Gastrointestinal Bleeding, Intensive Care Units, Risk Factors, Mortality, Cohort Study","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-07DOI: 10.21070/acopen.8.2023.7861
Zaenal Aulil Fauzany, Muhammad Alvan Rizki, Atik Wahyuni, Budwi Harsono
This scientific article addresses the pressing issue of environmental pollution arising from construction waste, particularly its adverse effects on water quality due to rapid urban development with insufficient environmental considerations. Employing a multidisciplinary approach encompassing literature review and legal analysis, this study investigates the detrimental impacts of construction waste pollution on human health, economic losses, and disruptions to natural ecosystems. The research underscores the critical need for enhanced awareness and action among government entities, contractors, and the public to safeguard the environment from the deleterious effects of construction waste pollution, thereby preserving natural ecosystems and upholding environmental standards. The study's findings emphasize the imperative role of governments in promoting environmental management and regulation, emphasizing the urgency of concerted efforts to address this global environmental challenge. Highlights: Construction waste pollution poses a significant threat to water quality and the environment, especially in rapidly urbanizing areas with inadequate environmental planning. This study employs a multidisciplinary approach, including literature review and legal analysis, to assess the adverse impacts of construction waste on human health, economics, and natural ecosystems. The research underscores the urgency of raising awareness and taking action, involving government bodies, contractors, and the public, to protect the environment, preserve natural ecosystems, and uphold environmental standards. Keywords: Construction Waste Pollution, Water Quality, Environmental Considerations, Multidisciplinary Approach, Environmental Management
{"title":"Mitigating Construction Waste Pollution for Environmental Sustainability: An Integrated Approach","authors":"Zaenal Aulil Fauzany, Muhammad Alvan Rizki, Atik Wahyuni, Budwi Harsono","doi":"10.21070/acopen.8.2023.7861","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7861","url":null,"abstract":"This scientific article addresses the pressing issue of environmental pollution arising from construction waste, particularly its adverse effects on water quality due to rapid urban development with insufficient environmental considerations. Employing a multidisciplinary approach encompassing literature review and legal analysis, this study investigates the detrimental impacts of construction waste pollution on human health, economic losses, and disruptions to natural ecosystems. The research underscores the critical need for enhanced awareness and action among government entities, contractors, and the public to safeguard the environment from the deleterious effects of construction waste pollution, thereby preserving natural ecosystems and upholding environmental standards. The study's findings emphasize the imperative role of governments in promoting environmental management and regulation, emphasizing the urgency of concerted efforts to address this global environmental challenge. Highlights: Construction waste pollution poses a significant threat to water quality and the environment, especially in rapidly urbanizing areas with inadequate environmental planning. This study employs a multidisciplinary approach, including literature review and legal analysis, to assess the adverse impacts of construction waste on human health, economics, and natural ecosystems. The research underscores the urgency of raising awareness and taking action, involving government bodies, contractors, and the public, to protect the environment, preserve natural ecosystems, and uphold environmental standards. Keywords: Construction Waste Pollution, Water Quality, Environmental Considerations, Multidisciplinary Approach, Environmental Management","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"5 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study explores the potential of solar energy as a sustainable alternative to coal-based electricity generation in Indonesia, aiming to address environmental concerns. It assesses the feasibility of household-level solar panel adoption for reducing electricity costs and enhancing energy self-sufficiency. Using photovoltaic technology, the research examines solar energy conversion and battery storage, focusing on optimal daylight utilization. Findings reveal substantial cost-saving prospects for households and stress the environmental benefits of decreasing reliance on conventional electricity sources. The study highlights the significance of public awareness and government support for solar panel adoption, emphasizing its role in economic stability and resource allocation to productive sectors. It advocates for empowering and educating the public about solar panel usage, which not only lowers electricity expenses but also promotes economic stability by reallocating funds to other industries, thus contributing to Indonesia's economic well-being and sustainable energy future. Highlights : This study evaluates solar energy's potential as a sustainable alternative to coal-based electricity in Indonesia, addressing environmental concerns. It emphasizes the feasibility of household-level solar panel adoption for cost reduction and energy self-sufficiency, focusing on photovoltaic technology and optimal daylight utilization. The research underscores the importance of public awareness and government support for solar panel adoption, highlighting its role in economic stability and resource allocation to productive sectors, ultimately contributing to a sustainable energy future. Keywords: Solar Energy, Sustainability, Household Adoption, Photovoltaic Technology, Environmental Benefits
{"title":"Solar Panel Implementation for Household Electricity in Indonesia: Environmental and Economic Implications","authors":"Nico Cahya Pradana Pradana, Muhammad Alvan Rizki, Atik Wahyuni, Budwi Harsono","doi":"10.21070/acopen.8.2023.7860","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7860","url":null,"abstract":"This study explores the potential of solar energy as a sustainable alternative to coal-based electricity generation in Indonesia, aiming to address environmental concerns. It assesses the feasibility of household-level solar panel adoption for reducing electricity costs and enhancing energy self-sufficiency. Using photovoltaic technology, the research examines solar energy conversion and battery storage, focusing on optimal daylight utilization. Findings reveal substantial cost-saving prospects for households and stress the environmental benefits of decreasing reliance on conventional electricity sources. The study highlights the significance of public awareness and government support for solar panel adoption, emphasizing its role in economic stability and resource allocation to productive sectors. It advocates for empowering and educating the public about solar panel usage, which not only lowers electricity expenses but also promotes economic stability by reallocating funds to other industries, thus contributing to Indonesia's economic well-being and sustainable energy future. Highlights : This study evaluates solar energy's potential as a sustainable alternative to coal-based electricity in Indonesia, addressing environmental concerns. It emphasizes the feasibility of household-level solar panel adoption for cost reduction and energy self-sufficiency, focusing on photovoltaic technology and optimal daylight utilization. The research underscores the importance of public awareness and government support for solar panel adoption, highlighting its role in economic stability and resource allocation to productive sectors, ultimately contributing to a sustainable energy future. Keywords: Solar Energy, Sustainability, Household Adoption, Photovoltaic Technology, Environmental Benefits","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.21070/acopen.8.2023.7830
Rawa Auda Hussein, Izdihar Nasaif Ali, Sarah Ashour Sayer
Polycystic Ovarian Syndrome (PCOS) is a prevalent endocrine disorder associated with infertility in a substantial number of women globally. This study aimed to investigate the potential role of oxytocin (OXT) in PCOS pathogenesis and its implications for oxidative stress. A cohort of 120 females, comprising 60 PCOS patients and 60 healthy controls, aged between 25 and 31, was examined. Serum concentrations of OXT, superoxide dismutase (SOD), and myeloperoxidase (MPO) were measured. The results revealed significantly decreased OXT levels in PCOS patients compared to controls (p<0.001). Additionally, PCOS patients exhibited elevated MPO levels and reduced SOD levels, suggesting increased oxidative stress. Furthermore, a positive correlation between OXT and SOD and a negative correlation between OXT and MPO were observed within the PCOS group. These findings highlight the potential of OXT as a diagnostic tool and predictor of ovarian response and treatment success in PCOS, emphasizing the need to target oxytocin for mitigating oxidative stress in this complex endocrine disorder. Highlights: Oxytocin Deficiency: This study identifies significantly reduced oxytocin levels in PCOS patients, shedding light on its potential role in the disorder's pathogenesis. Oxidative Stress Imbalance: PCOS patients displayed an imbalance in oxidative stress markers, with elevated myeloperoxidase and reduced superoxide dismutase levels, indicating increased oxidative stress. Diagnostic and Therapeutic Implications: Oxytocin emerges as a promising diagnostic tool and predictor of ovarian response and treatment success in PCOS, emphasizing its potential as a therapeutic target to mitigate oxidative stress in this complex endocrine disorder. Keywords: PCOS,Oxytocin,Oxidative Stress,Infertility,Diagnostic Tool
{"title":"Evaluation of Oxytocin Level and Its Relationship With Oxidant-Antioxidant Status in Women With Polycystic Ovarian Syndrome","authors":"Rawa Auda Hussein, Izdihar Nasaif Ali, Sarah Ashour Sayer","doi":"10.21070/acopen.8.2023.7830","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7830","url":null,"abstract":"Polycystic Ovarian Syndrome (PCOS) is a prevalent endocrine disorder associated with infertility in a substantial number of women globally. This study aimed to investigate the potential role of oxytocin (OXT) in PCOS pathogenesis and its implications for oxidative stress. A cohort of 120 females, comprising 60 PCOS patients and 60 healthy controls, aged between 25 and 31, was examined. Serum concentrations of OXT, superoxide dismutase (SOD), and myeloperoxidase (MPO) were measured. The results revealed significantly decreased OXT levels in PCOS patients compared to controls (p<0.001). Additionally, PCOS patients exhibited elevated MPO levels and reduced SOD levels, suggesting increased oxidative stress. Furthermore, a positive correlation between OXT and SOD and a negative correlation between OXT and MPO were observed within the PCOS group. These findings highlight the potential of OXT as a diagnostic tool and predictor of ovarian response and treatment success in PCOS, emphasizing the need to target oxytocin for mitigating oxidative stress in this complex endocrine disorder. Highlights: Oxytocin Deficiency: This study identifies significantly reduced oxytocin levels in PCOS patients, shedding light on its potential role in the disorder's pathogenesis. Oxidative Stress Imbalance: PCOS patients displayed an imbalance in oxidative stress markers, with elevated myeloperoxidase and reduced superoxide dismutase levels, indicating increased oxidative stress. Diagnostic and Therapeutic Implications: Oxytocin emerges as a promising diagnostic tool and predictor of ovarian response and treatment success in PCOS, emphasizing its potential as a therapeutic target to mitigate oxidative stress in this complex endocrine disorder. Keywords: PCOS,Oxytocin,Oxidative Stress,Infertility,Diagnostic Tool","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"2016 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139342179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.21070/acopen.8.2023.7844
Kareema A. Dakhil, Manal A. Aziz, W. J. Majid
This study aimed to investigate the potential of combining uric acid levels with pro-inflammatory cytokines, specifically interleukin-1β (IL-1β) and the myokine irisin, to enhance the precision of gout diagnosis. The patient group comprised 80 individuals with gout, while the control group included 70 healthy subjects. Serum levels of IL-1β and irisin were measured in both groups, and Pearson correlation analysis was employed to assess their relationships with serum uric acid. Results revealed that gout patients exhibited significantly higher levels of IL-1β and serum uric acid but lower irisin levels compared to the control group. Negative correlations were observed between irisin and IL-1β, as well as between irisin and uric acid. Conversely, a positive correlation was found between serum uric acid and IL-1β. Receiver operating characteristic (ROC) curve analysis demonstrated high diagnostic accuracy for both IL-1β and irisin in discriminating gout patients from healthy individuals, suggesting their potential utility as diagnostic indicators for gout. This study underscores the promise of combining IL-1β, irisin, and uric acid measurements to enhance the accuracy of gout diagnosis, paving the way for further multicenter trials to validate this approach's effectiveness. Highlights: Novel Diagnostic Approach: This study proposes a novel diagnostic approach for gout by combining serum levels of uric acid with pro-inflammatory cytokines IL-1β and myokine irisin, demonstrating its potential to enhance precision. Correlation Insights: The study reveals significant correlations between uric acid, IL-1β, and irisin levels, shedding light on the intricate relationship between inflammation, myokines, and gout pathophysiology. Diagnostic Accuracy: High diagnostic accuracy, as indicated by ROC curve analysis, underscores the clinical utility of IL-1β and irisin as potential indicators for gout diagnosis, offering a promising avenue for improved clinical assessment. Keywords: Gout Diagnosis, Interleukin-1β, Irisin, Uric Acid, Pro-Inflammatory Cytokines.
{"title":"Combination of Irisin, Uric Acid, and Pro-Inflammatory Cytokine To Distinguish Gout Patients From Healthy Controls in The Governorate of Thi-Qar","authors":"Kareema A. Dakhil, Manal A. Aziz, W. J. Majid","doi":"10.21070/acopen.8.2023.7844","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7844","url":null,"abstract":"This study aimed to investigate the potential of combining uric acid levels with pro-inflammatory cytokines, specifically interleukin-1β (IL-1β) and the myokine irisin, to enhance the precision of gout diagnosis. The patient group comprised 80 individuals with gout, while the control group included 70 healthy subjects. Serum levels of IL-1β and irisin were measured in both groups, and Pearson correlation analysis was employed to assess their relationships with serum uric acid. Results revealed that gout patients exhibited significantly higher levels of IL-1β and serum uric acid but lower irisin levels compared to the control group. Negative correlations were observed between irisin and IL-1β, as well as between irisin and uric acid. Conversely, a positive correlation was found between serum uric acid and IL-1β. Receiver operating characteristic (ROC) curve analysis demonstrated high diagnostic accuracy for both IL-1β and irisin in discriminating gout patients from healthy individuals, suggesting their potential utility as diagnostic indicators for gout. This study underscores the promise of combining IL-1β, irisin, and uric acid measurements to enhance the accuracy of gout diagnosis, paving the way for further multicenter trials to validate this approach's effectiveness. Highlights: Novel Diagnostic Approach: This study proposes a novel diagnostic approach for gout by combining serum levels of uric acid with pro-inflammatory cytokines IL-1β and myokine irisin, demonstrating its potential to enhance precision. Correlation Insights: The study reveals significant correlations between uric acid, IL-1β, and irisin levels, shedding light on the intricate relationship between inflammation, myokines, and gout pathophysiology. Diagnostic Accuracy: High diagnostic accuracy, as indicated by ROC curve analysis, underscores the clinical utility of IL-1β and irisin as potential indicators for gout diagnosis, offering a promising avenue for improved clinical assessment. Keywords: Gout Diagnosis, Interleukin-1β, Irisin, Uric Acid, Pro-Inflammatory Cytokines.","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139342198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.21070/acopen.8.2023.7843
Ridhab Ajeel Jasim, Saif Subhi Noori, Adeeb Shakir Mahmood, Asmaa Jumaa, Fatin Zuher Abd Alkareem
This study aimed to investigate the influence of COVID-19 vaccination on liver function and blood parameters, specifically Mean Corpuscular Volume (MCV) and Hemoglobin (HGB) levels, among young adults (aged 18-32) in Anbar province. Blood samples from 50 individuals were collected at Ramadi Teaching Hospital, with half of the participants vaccinated and the other half unvaccinated. Results revealed a significant decrease in MCV and HGB levels among the vaccinated group compared to the unvaccinated group. Concurrently, liver function indicators, including Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP), and Bilirubin, showed a marked increase in the vaccinated individuals, indicating potential hematological disorders and liver injury. These findings underscore the importance of COVID-19 vaccination while highlighting the need for continued monitoring of liver health and blood parameters in vaccinated individuals to mitigate potential long-term health implications. Highlights: COVID-19 vaccination in young adults may lead to a significant decrease in Mean Corpuscular Volume (MCV) and Hemoglobin (HGB) levels. Liver function indicators such as Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP), and Bilirubin exhibit a notable increase in vaccinated individuals. Continuous monitoring of liver health and blood parameters is crucial for assessing potential long-term health implications associated with COVID-19 vaccination. Keywords: COVID-19 Vaccination, Liver Function, Blood Parameters, Young Adults, Anbar Province.
{"title":"Hematological Parameters and Liver Function After COVID-19 Vaccination ( Simple Population Patients in Ramadi City – Iraq)","authors":"Ridhab Ajeel Jasim, Saif Subhi Noori, Adeeb Shakir Mahmood, Asmaa Jumaa, Fatin Zuher Abd Alkareem","doi":"10.21070/acopen.8.2023.7843","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7843","url":null,"abstract":"This study aimed to investigate the influence of COVID-19 vaccination on liver function and blood parameters, specifically Mean Corpuscular Volume (MCV) and Hemoglobin (HGB) levels, among young adults (aged 18-32) in Anbar province. Blood samples from 50 individuals were collected at Ramadi Teaching Hospital, with half of the participants vaccinated and the other half unvaccinated. Results revealed a significant decrease in MCV and HGB levels among the vaccinated group compared to the unvaccinated group. Concurrently, liver function indicators, including Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP), and Bilirubin, showed a marked increase in the vaccinated individuals, indicating potential hematological disorders and liver injury. These findings underscore the importance of COVID-19 vaccination while highlighting the need for continued monitoring of liver health and blood parameters in vaccinated individuals to mitigate potential long-term health implications. Highlights: COVID-19 vaccination in young adults may lead to a significant decrease in Mean Corpuscular Volume (MCV) and Hemoglobin (HGB) levels. Liver function indicators such as Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP), and Bilirubin exhibit a notable increase in vaccinated individuals. Continuous monitoring of liver health and blood parameters is crucial for assessing potential long-term health implications associated with COVID-19 vaccination. Keywords: COVID-19 Vaccination, Liver Function, Blood Parameters, Young Adults, Anbar Province.","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"2016 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139342171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.21070/acopen.8.2023.7814
Resi Intan Penatari, Terrensia Sekar Pamastutiningtyas, Rauhulloh Ayatulloh Khomeini Bintang
This study presents a comprehensive analysis of the implementation of green accounting in a local water supply utility (PDAM) and introduces a green accounting-based reporting model. The research aims to assess the internal and external perspectives of green accounting adoption within PDAM Sukoharjo, employing a descriptive qualitative method. Findings indicate that PDAM Sukoharjo has not fully embraced the green accounting concept. However, this study contributes by introducing a reporting model founded on green accounting principles, promising to enhance stakeholder satisfaction and promote sustainable practices in the water supply sector. Highlight: The study assesses the implementation of green accounting in a local water supply utility, offering insights into its adoption within the sector. Findings reveal that PDAM Sukoharjo has room for improvement in fully embracing the green accounting concept for sustainable practices. The research introduces a novel green accounting-based reporting model aimed at enhancing stakeholder satisfaction and promoting sustainability in the water supply industry. Keyword: Green Accounting, Water Supply Utility, Sustainability, Reporting Model, Stakeholder Satisfaction
{"title":"Towards Sustainable Practices: Green Accounting Implementation and Reporting Model in a Water Supply Utility","authors":"Resi Intan Penatari, Terrensia Sekar Pamastutiningtyas, Rauhulloh Ayatulloh Khomeini Bintang","doi":"10.21070/acopen.8.2023.7814","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7814","url":null,"abstract":"This study presents a comprehensive analysis of the implementation of green accounting in a local water supply utility (PDAM) and introduces a green accounting-based reporting model. The research aims to assess the internal and external perspectives of green accounting adoption within PDAM Sukoharjo, employing a descriptive qualitative method. Findings indicate that PDAM Sukoharjo has not fully embraced the green accounting concept. However, this study contributes by introducing a reporting model founded on green accounting principles, promising to enhance stakeholder satisfaction and promote sustainable practices in the water supply sector. Highlight: The study assesses the implementation of green accounting in a local water supply utility, offering insights into its adoption within the sector. Findings reveal that PDAM Sukoharjo has room for improvement in fully embracing the green accounting concept for sustainable practices. The research introduces a novel green accounting-based reporting model aimed at enhancing stakeholder satisfaction and promoting sustainability in the water supply industry. Keyword: Green Accounting, Water Supply Utility, Sustainability, Reporting Model, Stakeholder Satisfaction","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139342191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-04DOI: 10.21070/acopen.8.2023.7813
Dian Arisanti, Juli Prastyorini, Syahrul Fazizal Bachtiar
This study aims to identify and comprehend the implications on efficiency of Human Resources (HR), loading and unloading equipment, systems and procedures, as well as the operational aspects of Container Yard (CY) in a maritime terminal. Employing the SPSS methodology, our analysis reveals significant and profound impacts of HR (X1) on efficiency, with a beta coefficient of 0.523 (52.3%), highlighting HR's substantial contribution. Similarly, the isolated variable of Loading and Unloading Equipment (X2) exhibits a significant influence on efficiency, with a beta coefficient of 0.557 (55.7%). Moreover, System and Procedure (X3) demonstrate a noteworthy impact, with a beta coefficient of 0.511 (51.1%). Lastly, Container Yard (X4) also plays a significant role in efficiency, with a beta coefficient of 0.501 (50.2%). In sum, the combined effects of HR (X1), Loading and Unloading Equipment (X2), System and Procedure (X3), and Container Yard (X4) have a substantial influence on efficiency (Y) within the context of container handling operations. Highlight: HR Impact: Human Resources (HR) significantly contribute to efficiency in maritime terminal operations, accounting for 52.3% of the overall impact. Equipment Matters: Loading and unloading equipment play a crucial role, with a substantial 55.7% influence on operational efficiency. Procedural Efficiency: Effective systems and procedures, with a 51.1% impact, are essential for optimizing container handling operations in the maritime industry. Keyword: Efficiency, Human Resources, Loading and Unloading Equipment, Systems and Procedures, Container Yard
{"title":"Enhancing Efficiency in Container Handling Operations: A Multivariate Analysis","authors":"Dian Arisanti, Juli Prastyorini, Syahrul Fazizal Bachtiar","doi":"10.21070/acopen.8.2023.7813","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7813","url":null,"abstract":"This study aims to identify and comprehend the implications on efficiency of Human Resources (HR), loading and unloading equipment, systems and procedures, as well as the operational aspects of Container Yard (CY) in a maritime terminal. Employing the SPSS methodology, our analysis reveals significant and profound impacts of HR (X1) on efficiency, with a beta coefficient of 0.523 (52.3%), highlighting HR's substantial contribution. Similarly, the isolated variable of Loading and Unloading Equipment (X2) exhibits a significant influence on efficiency, with a beta coefficient of 0.557 (55.7%). Moreover, System and Procedure (X3) demonstrate a noteworthy impact, with a beta coefficient of 0.511 (51.1%). Lastly, Container Yard (X4) also plays a significant role in efficiency, with a beta coefficient of 0.501 (50.2%). In sum, the combined effects of HR (X1), Loading and Unloading Equipment (X2), System and Procedure (X3), and Container Yard (X4) have a substantial influence on efficiency (Y) within the context of container handling operations. Highlight: HR Impact: Human Resources (HR) significantly contribute to efficiency in maritime terminal operations, accounting for 52.3% of the overall impact. Equipment Matters: Loading and unloading equipment play a crucial role, with a substantial 55.7% influence on operational efficiency. Procedural Efficiency: Effective systems and procedures, with a 51.1% impact, are essential for optimizing container handling operations in the maritime industry. Keyword: Efficiency, Human Resources, Loading and Unloading Equipment, Systems and Procedures, Container Yard","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139342941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.21070/acopen.8.2023.7763
Ola Jamal Yasien, Fadia J. Al Izzi
Elevated levels of Fetuin-A, a protease inhibitor belonging to the cystatin family, have raised questions about its role in the pathogenesis of Polycystic Ovarian Syndrome (PCOS), the most prevalent endocrinopathy in reproductive-aged females. This case-control study, conducted in Iraq, aimed to assess changes in Fetuin-A levels among Iraqi women with PCOS. A convenient sample of 90 women, comprising 45 PCOS cases and 45 healthy controls, was enrolled. Fetuin-A levels were measured and found to be significantly higher in the PCOS group compared to controls. Additionally, significant positive correlations were observed between Fetuin-A levels and fasting plasma glucose, fasting serum insulin, insulin resistance, luteinizing hormone, and serum testosterone. Using a receiver operating characteristic curve, a cutoff point of 502.00 ng/mL was determined for predicting positive Fetuin-A levels, with a sensitivity and specificity of 84.4% and 73.3%, respectively. This study suggests that Fetuin-A could serve as a valuable marker for both screening and evaluating PCOS and its potential late consequences, including metabolic syndrome. Highlights: Elevated Fetuin-A Levels: This study reveals significantly higher Fetuin-A levels in PCOS, shedding light on its potential role in the pathogenesis of the syndrome. Correlations with Metabolic Factors: Positive correlations between Fetuin-A and key metabolic markers like fasting glucose, insulin resistance, and luteinizing hormone highlight its relevance in the context of PCOS and metabolic health. Screening Potential: The identified cutoff point for predicting positive Fetuin-A levels offers a promising tool for screening and evaluating PCOS and associated late consequences, particularly metabolic syndrome.
{"title":"Evaluation of Serum Fetuin-A as A Possible Marker for Polycystic Ovarian Syndrome Among Iraqi Women; Case-control Study","authors":"Ola Jamal Yasien, Fadia J. Al Izzi","doi":"10.21070/acopen.8.2023.7763","DOIUrl":"https://doi.org/10.21070/acopen.8.2023.7763","url":null,"abstract":"Elevated levels of Fetuin-A, a protease inhibitor belonging to the cystatin family, have raised questions about its role in the pathogenesis of Polycystic Ovarian Syndrome (PCOS), the most prevalent endocrinopathy in reproductive-aged females. This case-control study, conducted in Iraq, aimed to assess changes in Fetuin-A levels among Iraqi women with PCOS. A convenient sample of 90 women, comprising 45 PCOS cases and 45 healthy controls, was enrolled. Fetuin-A levels were measured and found to be significantly higher in the PCOS group compared to controls. Additionally, significant positive correlations were observed between Fetuin-A levels and fasting plasma glucose, fasting serum insulin, insulin resistance, luteinizing hormone, and serum testosterone. Using a receiver operating characteristic curve, a cutoff point of 502.00 ng/mL was determined for predicting positive Fetuin-A levels, with a sensitivity and specificity of 84.4% and 73.3%, respectively. This study suggests that Fetuin-A could serve as a valuable marker for both screening and evaluating PCOS and its potential late consequences, including metabolic syndrome. Highlights: Elevated Fetuin-A Levels: This study reveals significantly higher Fetuin-A levels in PCOS, shedding light on its potential role in the pathogenesis of the syndrome. Correlations with Metabolic Factors: Positive correlations between Fetuin-A and key metabolic markers like fasting glucose, insulin resistance, and luteinizing hormone highlight its relevance in the context of PCOS and metabolic health. Screening Potential: The identified cutoff point for predicting positive Fetuin-A levels offers a promising tool for screening and evaluating PCOS and associated late consequences, particularly metabolic syndrome.","PeriodicalId":299489,"journal":{"name":"Academia Open","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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