Dyes and Pigments最新文献

英文中文

Small organic molecules-based NIR agents in cancer diagnostics: New frontiers in imaging and therapy

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-27 DOI: 10.1016/j.dyepig.2025.112648

Amal Adnan Ashour , Mohammed Fareed Felemban , Faris J. Tayeb , Abeer Alubaidi , Alaa Shafie

Cancer is the leading cause of death worldwide, with millions of new cases and fatalities reported each year. Early detection plays a critical role in improving treatment outcomes and survival rates, as it allows for timely intervention and more effective therapies. Traditional diagnostic methods often face limitations in sensitivity, specificity, and the ability to detect tumors at an early stage. Therefore, there is a growing need for advanced diagnostic tools that can offer higher precision and earlier detection of cancer. In this regard, Near-Infrared (NIR) imaging has emerged as a promising technique, offering non-invasive, real-time, and high-resolution imaging capabilities for tumor visualization. Small organic molecules-based NIR agents have recently garnered attention in the field of cancer diagnostics due to their superior biocompatibility, tunable properties, and ability to penetrate deeper into tissues. These agents, including various organic fluorophores, that are designed to enhance the sensitivity and specificity of cancer imaging, enabling the detection of smaller tumors that are otherwise challenging to identify. This review aims to provide an overview of the latest advancements (2020–2025) in small organic molecules-based NIR agents for various cancer diagnosis, focusing on their development, applications, and potential for clinical use. By examining key innovations in this area, this article seeks to highlight the impact of small organic molecules-based NIR agents on the future of cancer theranostics.

{"title":"Small organic molecules-based NIR agents in cancer diagnostics: New frontiers in imaging and therapy","authors":"Amal Adnan Ashour , Mohammed Fareed Felemban , Faris J. Tayeb , Abeer Alubaidi , Alaa Shafie","doi":"10.1016/j.dyepig.2025.112648","DOIUrl":"10.1016/j.dyepig.2025.112648","url":null,"abstract":"<div><div>Cancer is the leading cause of death worldwide, with millions of new cases and fatalities reported each year. Early detection plays a critical role in improving treatment outcomes and survival rates, as it allows for timely intervention and more effective therapies. Traditional diagnostic methods often face limitations in sensitivity, specificity, and the ability to detect tumors at an early stage. Therefore, there is a growing need for advanced diagnostic tools that can offer higher precision and earlier detection of cancer. In this regard, Near-Infrared (NIR) imaging has emerged as a promising technique, offering non-invasive, real-time, and high-resolution imaging capabilities for tumor visualization. Small organic molecules-based NIR agents have recently garnered attention in the field of cancer diagnostics due to their superior biocompatibility, tunable properties, and ability to penetrate deeper into tissues. These agents, including various organic fluorophores, that are designed to enhance the sensitivity and specificity of cancer imaging, enabling the detection of smaller tumors that are otherwise challenging to identify. This review aims to provide an overview of the latest advancements (2020–2025) in small organic molecules-based NIR agents for various cancer diagnosis, focusing on their development, applications, and potential for clinical use. By examining key innovations in this area, this article seeks to highlight the impact of small organic molecules-based NIR agents on the future of cancer theranostics.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"236 ","pages":"Article 112648"},"PeriodicalIF":4.1,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic engineering of Escherichia coli BL21(DE3) for efficient production of indigo using Methylophaga aminisulfidivorans flavin-containing monooxygenase

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-27 DOI: 10.1016/j.dyepig.2025.112682

Rui Lu , Roulin Chen , Zeyu Li , Heng Hu , Zhimeng Wu , Yingying Zhu , Wanmeng Mu

Biological production of indigo can be achieved by enzymatic hydroxylation of indole, the degradation product of tryptophan. Many oxygenases have been identified to be capable of producing indigo from indole, among which flavin-containing monooxygenase (FMO) is the most extensively studied. In this study, Escherichia coli BL21 (DE3) was metabolically engineered to efficiently produce indigo using FMO. Five reported indigo-producing FMOs and five homologous human FMOs were selected to evaluate the in vivo indigo production abilities, in which Methylophaga aminisulfidivorans FMO showed the highest indigo titer. Various metabolic engineering strategies were performed to stepwise enhance the indigo titer, including strengthening tryptophan transportation, blocking tryptophan synthesis-related competitive pathways, regulating key metabolic genes for tryptophan synthesis. When supplemented with tryptophan, the final engineered strain produced 532 and 1492 mg/L of indigo by shake-flask and fed-batch cultivation, respectively.

{"title":"Metabolic engineering of Escherichia coli BL21(DE3) for efficient production of indigo using Methylophaga aminisulfidivorans flavin-containing monooxygenase","authors":"Rui Lu , Roulin Chen , Zeyu Li , Heng Hu , Zhimeng Wu , Yingying Zhu , Wanmeng Mu","doi":"10.1016/j.dyepig.2025.112682","DOIUrl":"10.1016/j.dyepig.2025.112682","url":null,"abstract":"<div><div>Biological production of indigo can be achieved by enzymatic hydroxylation of indole, the degradation product of tryptophan. Many oxygenases have been identified to be capable of producing indigo from indole, among which flavin-containing monooxygenase (FMO) is the most extensively studied. In this study, <em>Escherichia coli</em> BL21 (DE3) was metabolically engineered to efficiently produce indigo using FMO. Five reported indigo-producing FMOs and five homologous human FMOs were selected to evaluate the <em>in vivo</em> indigo production abilities, in which <em>Methylophaga aminisulfidivorans</em> FMO showed the highest indigo titer. Various metabolic engineering strategies were performed to stepwise enhance the indigo titer, including strengthening tryptophan transportation, blocking tryptophan synthesis-related competitive pathways, regulating key metabolic genes for tryptophan synthesis. When supplemented with tryptophan, the final engineered strain produced 532 and 1492 mg/L of indigo by shake-flask and fed-batch cultivation, respectively.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"236 ","pages":"Article 112682"},"PeriodicalIF":4.1,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel amyloid-β oligomer-targeted fluorescent probes by introducing branched chain into push-pull type dye

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-25 DOI: 10.1016/j.dyepig.2025.112680

Rikuto Kashiyama , Hiroyuki Watanabe , Takahiro Akasaka, Masahiro Ono

Amyloid-β (Aβ) oligomer is one of the major targets for the diagnosis and treatment of Alzheimer's disease (AD). Therefore, the development of useful methods to selectively detect Aβ oligomers is needed. In this study, we newly designed and synthesized four fluorescent probes (DBP) that contained a branched chain in the scaffold of push-pull type dyes targeting Aβ fibrils, and evaluated their utility for the detection of Aβ oligomers. All DBP derivatives showed higher fluorescence intensity with Aβ oligomers than Aβ fibrils. Among them, DBP-2 clearly stained Aβ oligomers in the brain section of an AD model mouse. The results of the docking study indicate that DBP-2 interacted with the hydrophobic region in the Aβ trimer structure. In an ex vivo study using the AD model mouse, DBP-2 penetrated the blood-brain barrier and bound to not only Aβ fibrils but also Aβ oligomers, although it also bound to other intracellular components. The results suggest that DBP-2 is effective as a fluorescent probe targeting Aβ oligomers.

引用次数: 0

Ultralong organic room temperature phosphorescence polymers enabled by chemically locking dopant internal rotation

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-23 DOI: 10.1016/j.dyepig.2025.112679

Zhichao Mao, Guotian Zhang, Haoyi Ma, Jinbin Liu, Shanfeng Xue, Qikun Sun, Wenjun Yang

Ultralong organic room temperature phosphorescence (UORTP) polymers have attracted a growing interest in organic electronics and photonics fields. Although, amount of RTP molecules embed in polymer matrix is designed and constructed, it's still a stern challenge to explore a universal chemical/physical approach to obtain UORTP. Herein, a feasible and effective strategy is presented to achieve UORTP systems through doping three molecules, which were designed and synthesized successfully by chemical locking, into a poly (methyl methacrylate) matrix to form definite size films by thermo-plastic processing. Interestingly, three molecules with chemical locking modification that displays UORTP in a doped polymer matrix with lifetimes up to 2.33 s, 2.15 s, 2.50 s. The successful construction of these UORTP systems can be ascribed to i) effective suppression of thermal vibration nonradiation decay by chemical locking; ii) effective reduction of triplet excitons nonradiative decay rate via the formation of a more rigid microenvironment and electrostatic interaction between the PMMA matrix and three molecules. As a result, this work not only facilitate the design of UORTP materials by chemical locking design strategy, but also endow traditional polymers with fresh features for potential applications.

{"title":"Ultralong organic room temperature phosphorescence polymers enabled by chemically locking dopant internal rotation","authors":"Zhichao Mao, Guotian Zhang, Haoyi Ma, Jinbin Liu, Shanfeng Xue, Qikun Sun, Wenjun Yang","doi":"10.1016/j.dyepig.2025.112679","DOIUrl":"10.1016/j.dyepig.2025.112679","url":null,"abstract":"<div><div>Ultralong organic room temperature phosphorescence (UORTP) polymers have attracted a growing interest in organic electronics and photonics fields. Although, amount of RTP molecules embed in polymer matrix is designed and constructed, it's still a stern challenge to explore a universal chemical/physical approach to obtain UORTP. Herein, a feasible and effective strategy is presented to achieve UORTP systems through doping three molecules, which were designed and synthesized successfully by chemical locking, into a poly (methyl methacrylate) matrix to form definite size films by thermo-plastic processing. Interestingly, three molecules with chemical locking modification that displays UORTP in a doped polymer matrix with lifetimes up to 2.33 s, 2.15 s, 2.50 s. The successful construction of these UORTP systems can be ascribed to i) effective suppression of thermal vibration nonradiation decay by chemical locking; ii) effective reduction of triplet excitons nonradiative decay rate via the formation of a more rigid microenvironment and electrostatic interaction between the PMMA matrix and three molecules. As a result, this work not only facilitate the design of UORTP materials by chemical locking design strategy, but also endow traditional polymers with fresh features for potential applications.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"236 ","pages":"Article 112679"},"PeriodicalIF":4.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tungsten disulfide quantum dots: Synthesis, structure, properties and biological applications

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-23 DOI: 10.1016/j.dyepig.2025.112668

Yongming Guo, Yixia Liu, Yubin Xiang

Transition metal dichalcogenides have attracted considerable attention due to their adjustable bandgap structures. When their size is further reduced, quantum dots with different emissions will emerge. Over the past few years, a variety of strategies have been developed for the fabrication of tungsten disulfide quantum dots (WS₂ QDs), and plenty of applications have been exploited. In this review, we first summarized the synthetic approaches of WS₂ QDs. The synthetic strategies were divided into top-down and bottom-up. We further briefly discussed their unique structure and properties, including fluorescence, biocompatibility, and peroxidase-like activity. Subsequently, we highlighted the recent progress of WS₂ QDs in biological applications, including bioimaging, biosensing, and biomedicine. Lastly, the challenges and perspectives on the synthesis of WS₂ QDs and biological applications are discussed.

引用次数: 0

Multi-resonance skeleton connected by rigid B- and N-embedded dioxygen-bridged units: Investigating structure–property relationships

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-23 DOI: 10.1016/j.dyepig.2025.112681

Zhen Jiang , Qiyin Chen , Chao Shi , Jie Su , Feiyang Li , Kaishun Ye , Zhigang Zhao , Qiuxia Li , Aihua Yuan , Guohua Xie

Two novel multi-resonance (MR) skeleton-based thermally activated delayed fluorescence (TADF) derivatives (NO-BN and BO-BN), incorporating rigid B- and N-embedded dioxygen-bridged units (BO and NO), were synthesized and characterized. The single-crystal structure of NO-BO shows that both MR and NO units exhibit good planarity and induce interesting head-to-tail π−π interactions. Notably, two compounds exhibit different intramolecular charge-transfer character according to theoretical calculations and photophysical results. The lowest excited singlet state of BO-BN mainly shows the local excited state (LE) characteristics of MR unit, accompanied by weak charge transfer state characteristics from MR Unit to BO unit, while only obvious CT state characteristics from NO unit to MR unit can be found in S₁ of NO-BN. As a result, BO-BN (FWHM = 40 nm and Φ_PL = 90 %) demonstates a narrower full width at half maximum (FWHM) and a higher emission efficiency than NO-BN (FWHM = 50 nm and Φ_PL = 49 %). The compound BO-BN was selected as the guest emitter in a solution-processed OLED, achieving an excellent maximum external quantum efficiency of 24 %, along with saturated green emission at 510 nm. These findings provide a good understanding of the structure-property relationships in MR skeleton-based TADF materials.

{"title":"Multi-resonance skeleton connected by rigid B- and N-embedded dioxygen-bridged units: Investigating structure–property relationships","authors":"Zhen Jiang , Qiyin Chen , Chao Shi , Jie Su , Feiyang Li , Kaishun Ye , Zhigang Zhao , Qiuxia Li , Aihua Yuan , Guohua Xie","doi":"10.1016/j.dyepig.2025.112681","DOIUrl":"10.1016/j.dyepig.2025.112681","url":null,"abstract":"<div><div>Two novel multi-resonance (MR) skeleton-based thermally activated delayed fluorescence (TADF) derivatives (<strong>NO-BN</strong> and <strong>BO-BN</strong>), incorporating rigid B- and N-embedded dioxygen-bridged units (BO and NO), were synthesized and characterized. The single-crystal structure of <strong>NO-BO</strong> shows that both MR and NO units exhibit good planarity and induce interesting head-to-tail π−π interactions. Notably, two compounds exhibit different intramolecular charge-transfer character according to theoretical calculations and photophysical results. The lowest excited singlet state of <strong>BO-BN</strong> mainly shows the local excited state (LE) characteristics of MR unit, accompanied by weak charge transfer state characteristics from MR Unit to BO unit, while only obvious CT state characteristics from NO unit to MR unit can be found in S<sub>1</sub> of <strong>NO-BN</strong>. As a result, <strong>BO-BN</strong> (FWHM = 40 nm and Φ<sub>PL</sub> = 90 %) demonstates a narrower full width at half maximum (FWHM) and a higher emission efficiency than <strong>NO-BN</strong> (FWHM = 50 nm and Φ<sub>PL</sub> = 49 %). The compound <strong>BO-BN</strong> was selected as the guest emitter in a solution-processed OLED, achieving an excellent maximum external quantum efficiency of 24 %, along with saturated green emission at 510 nm. These findings provide a good understanding of the structure-property relationships in MR skeleton-based TADF materials.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"236 ","pages":"Article 112681"},"PeriodicalIF":4.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing buried interface quality in inverted perovskite solar cells by modulating the spatial orientation of polymer hole transport materials using rigid copolymer units

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-22 DOI: 10.1016/j.dyepig.2025.112676

Xiaoran Yan , Mengdan Yang , Weihao Li , Yin Liu , Huidong Zhang , Xiangfei Kong , Zhenguang Hu , Yongzhen Wu , Haijun Tan

Optimizing the interfacial properties of functional layers is a critical strategy for enhancing the performance of inverted perovskite solar cells (PSCs). In this study, three phenothiazine-based polymer hole transport materials (HTMs) were designed and synthesized, utilizing fluorene, 9-fluorenone, and phenanthrenequinone as copolymer units, (PPTZ-FOM-0, PPTZ-FOM-1, and PPTZ-FOM-2, respectively). Notably, PPTZ-FOM-0 and PPTZ-FOM-1 exhibited helical spatial stacking. However, due to the high rigidity of the copolymer phenanthrenequinone, PPTZ-FOM-2 transitioned to a chain-like planar conformation, which enhanced the exposure of functional groups and heteroatoms. This transformation significantly improved the film surface flatness and wettability, resulting in a reduction of the film root-mean-square surface roughness (RMS) from 24.8 nm (PPTZ-FOM-0) to 18.3 nm and a reduction of the contact angle with the perovskite precursor solution from 60.6° (PPTZ-FOM-0) to 38.3°. These properties are advantageous for the crystal growth of the perovskite layer and effectively suppress non-radiative recombination at the interface, optimizing buried interface quality in inverted PSCs. Ultimately, the power conversion efficiency (PCE) of the PSCs device based on PPTZ-FOM-2 significantly increased from 15.3 % (PPTZ-FOM-0) to 17.3 %.

{"title":"Optimizing buried interface quality in inverted perovskite solar cells by modulating the spatial orientation of polymer hole transport materials using rigid copolymer units","authors":"Xiaoran Yan , Mengdan Yang , Weihao Li , Yin Liu , Huidong Zhang , Xiangfei Kong , Zhenguang Hu , Yongzhen Wu , Haijun Tan","doi":"10.1016/j.dyepig.2025.112676","DOIUrl":"10.1016/j.dyepig.2025.112676","url":null,"abstract":"<div><div>Optimizing the interfacial properties of functional layers is a critical strategy for enhancing the performance of inverted perovskite solar cells (PSCs). In this study, three phenothiazine-based polymer hole transport materials (HTMs) were designed and synthesized, utilizing fluorene, 9-fluorenone, and phenanthrenequinone as copolymer units, (<strong>PPTZ-FOM-0</strong>, <strong>PPTZ-FOM-1</strong>, and <strong>PPTZ-FOM-2</strong>, respectively). Notably, <strong>PPTZ-FOM-0</strong> and <strong>PPTZ-FOM-1</strong> exhibited helical spatial stacking. However, due to the high rigidity of the copolymer phenanthrenequinone, <strong>PPTZ-FOM-2</strong> transitioned to a chain-like planar conformation, which enhanced the exposure of functional groups and heteroatoms. This transformation significantly improved the film surface flatness and wettability, resulting in a reduction of the film root-mean-square surface roughness (RMS) from 24.8 nm (<strong>PPTZ-FOM-0</strong>) to 18.3 nm and a reduction of the contact angle with the perovskite precursor solution from 60.6° (<strong>PPTZ-FOM-0</strong>) to 38.3°. These properties are advantageous for the crystal growth of the perovskite layer and effectively suppress non-radiative recombination at the interface, optimizing buried interface quality in inverted PSCs. Ultimately, the power conversion efficiency (PCE) of the PSCs device based on <strong>PPTZ-FOM-2</strong> significantly increased from 15.3 % (<strong>PPTZ-FOM-0</strong>) to 17.3 %.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"236 ","pages":"Article 112676"},"PeriodicalIF":4.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparation of stable liquid disperse dye using the antisolvent precipitation method for enhancing dyeability and eco-friendliness

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-21 DOI: 10.1016/j.dyepig.2025.112655

Ziting Ma , Fuyang Gu , Xiaoyan Wang , Guowei Xiao , Yang Jiang , Jinmei Du , Liang He , Yongjun Yu , Xiyu Song , Changhai Xu

The objective of this study is to identify the optimal conditions for preparing liquid disperse dyes via the antisolvent precipitation method. Conventional liquid disperse dyes are typically produced via a top-down process, which possesses inherent limitations including high energy consumption. Antisolvent precipitation, as a bottom-up method, has not yet been widely adopted in commercial production of liquid disperse dye products. Utilizing this method to prepare dye suspensions could potentially reduce the energy consumption associated with the production of liquid disperse dyes. Herein, the particle size of dyes precipitated in the antisolvent was controlled by introducing surfactants at the early stage of precipitation, successfully producing small particle size liquid dispersions. The dye particle size was 10 μm before adding the dp510 dispersant and decreased to 242 nm afterward. The effect of different process parameters on the particle size, stability and dyeing properties were investigated.

{"title":"Preparation of stable liquid disperse dye using the antisolvent precipitation method for enhancing dyeability and eco-friendliness","authors":"Ziting Ma , Fuyang Gu , Xiaoyan Wang , Guowei Xiao , Yang Jiang , Jinmei Du , Liang He , Yongjun Yu , Xiyu Song , Changhai Xu","doi":"10.1016/j.dyepig.2025.112655","DOIUrl":"10.1016/j.dyepig.2025.112655","url":null,"abstract":"<div><div>The objective of this study is to identify the optimal conditions for preparing liquid disperse dyes via the antisolvent precipitation method. Conventional liquid disperse dyes are typically produced via a top-down process, which possesses inherent limitations including high energy consumption. Antisolvent precipitation, as a bottom-up method, has not yet been widely adopted in commercial production of liquid disperse dye products. Utilizing this method to prepare dye suspensions could potentially reduce the energy consumption associated with the production of liquid disperse dyes. Herein, the particle size of dyes precipitated in the antisolvent was controlled by introducing surfactants at the early stage of precipitation, successfully producing small particle size liquid dispersions. The dye particle size was 10 μm before adding the dp510 dispersant and decreased to 242 nm afterward. The effect of different process parameters on the particle size, stability and dyeing properties were investigated.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"236 ","pages":"Article 112655"},"PeriodicalIF":4.1,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simple nonfullerene acceptors achieving NIR absorption regulation via alkoxy functionalization on the π-spacers

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-21 DOI: 10.1016/j.dyepig.2025.112667

Yuanyuan Zhou , Yaohua Shi , Shuaishuai Shen , Miao Li , Xiaodan Tang , Ruiping Qin , Zheng Tang , Jinsheng Song

Non-fused ring acceptors (NFRAs) with simple molecular structure shows a bright prospect for high efficiency acceptors in commercial applications due to the easy synthesis and low cost. Herein, ethylhexyloxy is selected as the side chain on the π-spacer of the A-π-D-π-A type NFRAs, the orientation direction and amount have been carefully considered, which could regulate the band-edges of the absorption spectra ranging from 900 nm to 1120 nm. Hence, the inner alkoxy modified DTC-O_iT-4F could reach a rather narrow bandgap of 1.10 eV due to the conformation locks, while the outer derived strategy in DTC-O_oT-4F and DTC-O_oiT-4F is effective at the LUMO improving. Utilization of PBDB-T as the donor, organic solar cells are constructed with these acceptors, and power conversion efficiencies (PCEs) of 5.50 %, 10.02 % and 10.58 % are acquired for DTC-O_iT-4F, DTC-O_oT-4F and DTC-O_oiT-4F based devices, respectively. The conformation prediction, morphology study, crystallization orientation and energy loss analysis have been fully discussed in this work. In all, our studies have demonstrated that appropriate utilization of the alkoxy side chain on the π-spacer of the noncovalently locked simple A-π-D-π-A acceptors could effectively change its electronic characteristics and may offer some simple strategy for the design of high efficiency NFRAs.

{"title":"Simple nonfullerene acceptors achieving NIR absorption regulation via alkoxy functionalization on the π-spacers","authors":"Yuanyuan Zhou , Yaohua Shi , Shuaishuai Shen , Miao Li , Xiaodan Tang , Ruiping Qin , Zheng Tang , Jinsheng Song","doi":"10.1016/j.dyepig.2025.112667","DOIUrl":"10.1016/j.dyepig.2025.112667","url":null,"abstract":"<div><div>Non-fused ring acceptors (NFRAs) with simple molecular structure shows a bright prospect for high efficiency acceptors in commercial applications due to the easy synthesis and low cost. Herein, ethylhexyloxy is selected as the side chain on the π-spacer of the A-π-D-π-A type NFRAs, the orientation direction and amount have been carefully considered, which could regulate the band-edges of the absorption spectra ranging from 900 nm to 1120 nm. Hence, the inner alkoxy modified <strong>DTC-O</strong><sub><strong><em>i</em></strong></sub><strong>T-4F</strong> could reach a rather narrow bandgap of 1.10 eV due to the conformation locks, while the outer derived strategy in <strong>DTC-O</strong><sub><strong><em>o</em></strong></sub><strong>T-4F</strong> and <strong>DTC-O</strong><sub><strong><em>oi</em></strong></sub><strong>T-4F</strong> is effective at the LUMO improving. Utilization of PBDB-T as the donor, organic solar cells are constructed with these acceptors, and power conversion efficiencies (PCEs) of 5.50 %, 10.02 % and 10.58 % are acquired for <strong>DTC-O</strong><sub><strong><em>i</em></strong></sub><strong>T-4F</strong>, <strong>DTC-O</strong><sub><strong><em>o</em></strong></sub><strong>T-4F</strong> and <strong>DTC-O</strong><sub><strong><em>oi</em></strong></sub><strong>T-4F</strong> based devices, respectively. The conformation prediction, morphology study, crystallization orientation and energy loss analysis have been fully discussed in this work. In all, our studies have demonstrated that appropriate utilization of the alkoxy side chain on the π-spacer of the noncovalently locked simple A-π-D-π-A acceptors could effectively change its electronic characteristics and may offer some simple strategy for the design of high efficiency NFRAs.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"236 ","pages":"Article 112667"},"PeriodicalIF":4.1,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Donor-imine-acceptor-based small organic molecule for efficient photothermal therapy

IF 4.1 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments

Pub Date : 2025-01-20 DOI: 10.1016/j.dyepig.2025.112664

Thanh Chung Pham , Hyejin Kim , Van Kieu Thuy Nguyen , Yeonghwan Choi , Hyun Wook Kang , Songyi Lee

The development of small molecules with high photothermal conversion efficiency (PCE) poses a significant challenge in the context of photothermal therapy, a promising modality for cancer treatment. While certain efficient small molecules have been documented in the literature, they often incorporate bulky alkyl chains and/or aromatic rings to enhance the photothermal effect. Hence, this study presents a novel and straightforward method for synthesizing a photothermal small molecule, designated as PA2, utilizing a donor-acceptor framework. In this framework, diphenylamine is employed as the donor moiety, while 1,3-Bis(dicyanomethylidene)indan is utilized as the acceptor moiety. PA2 demonstrated high PCE in both monomer and but also in aggregate state. In which, the excitation energy is efficiently released as heat via non-radiative decay through the conical intersection (CI) as confirmed by a computationally optimized minimum energy crossing point (MECP) and a combination of further theoretical studies and experimental control groups (PA3 and PA4). Notably, the resulting molecular architecture exhibits remarkable efficacy in inhibiting tumor growth after a 10-day photothermal therapy period. Furthermore, in vivo experiments in a mouse tumor model demonstrate the favorable biocompatibility of these photothermal small molecules, signifying their suitability for safe application in biomedical contexts. This study makes a substantial contribution to the field of photothermal therapy by introducing a novel molecular design paradigm based on small molecules.

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