Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.104
Himanshu Nayak, Subhas Chandra Majhi, Sameer Kiro, M. Murmu, Pitambar Murmu, Shitanshu Kumar Meher, Sanjukta Panda
Iron deficiency is the most common nutritional deficiency worldwide & it is an important public health problem in developing countries like India. Normally chronic hemolytic anemia are iron loaded because of excessive breakdown of RBC & increased frequency of blood transfusion, but there is small or no transfusion on sickle cell trait. This study has been done to see the iron profile among sickle cell trait children in western Odisha. To determine the iron profile in children with sickle cell trait & normal healthy controls & compare them. This was a case control study that has been conducted over a period of two years. A total of 202 subjects were included in the study; 102 of them were sickle cell heterozygous & 100 of them were normal healthy controls. Iron deficiency anemia among sickle cell trait & healthy controls were screened using various clinical & laboratory criteria. A total of 202(n=202) study populations comprising of 102 sickle cell trait & 100 normal study populations were screened. A little female preponderance (n=109, 54%) was observed in this study. Abnormalities in blood parameters like MCV, MCH, MCHC, Serum ferritin were found to be statistically significant (p<0.005). Others clinical features like pallor, picophagia, sore tongue, fatigue was also found to be statistically significant (p<0.005). Out of 202 study populations 17 out of 102 sickle cell trait cases & 16 out of 100 normal controls were found to have Iron deficiency anemia. In this study it showed that there were many sickle cell trait patients who were actually iron deficient. These patients should be screened carefully to look for Iron deficiency anemia. Clinical parameters like pallor, fatigue, picophagia, sore tongue & others laboratories parameters like MCV, MCH, MCHC, Serum ferritin were helpful in diagnosing Iron deficiency anemia.
{"title":"Iron profile in sickle cell heterozygous children: A case control study","authors":"Himanshu Nayak, Subhas Chandra Majhi, Sameer Kiro, M. Murmu, Pitambar Murmu, Shitanshu Kumar Meher, Sanjukta Panda","doi":"10.18231/j.pjms.2023.104","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.104","url":null,"abstract":"Iron deficiency is the most common nutritional deficiency worldwide & it is an important public health problem in developing countries like India. Normally chronic hemolytic anemia are iron loaded because of excessive breakdown of RBC & increased frequency of blood transfusion, but there is small or no transfusion on sickle cell trait. This study has been done to see the iron profile among sickle cell trait children in western Odisha. To determine the iron profile in children with sickle cell trait & normal healthy controls & compare them. This was a case control study that has been conducted over a period of two years. A total of 202 subjects were included in the study; 102 of them were sickle cell heterozygous & 100 of them were normal healthy controls. Iron deficiency anemia among sickle cell trait & healthy controls were screened using various clinical & laboratory criteria. A total of 202(n=202) study populations comprising of 102 sickle cell trait & 100 normal study populations were screened. A little female preponderance (n=109, 54%) was observed in this study. Abnormalities in blood parameters like MCV, MCH, MCHC, Serum ferritin were found to be statistically significant (p<0.005). Others clinical features like pallor, picophagia, sore tongue, fatigue was also found to be statistically significant (p<0.005). Out of 202 study populations 17 out of 102 sickle cell trait cases & 16 out of 100 normal controls were found to have Iron deficiency anemia. In this study it showed that there were many sickle cell trait patients who were actually iron deficient. These patients should be screened carefully to look for Iron deficiency anemia. Clinical parameters like pallor, fatigue, picophagia, sore tongue & others laboratories parameters like MCV, MCH, MCHC, Serum ferritin were helpful in diagnosing Iron deficiency anemia.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.111
Shikha Agarwal, Praveen Sablania
National health & nutritional examination survey, 1988-1994, first time reported a significant positive association in iron storage & heart disease risk. Due to the scarcity of this type of study in India, we did this study to find out the relation of serum ferritin with MIThe current study attempts to evaluation association of ferritin levels at the onset of AMI & at 6 day of follow up of subjects. A total of 39 male patients who were confirmed of having MI on the basis of lipid profile, CKMB, SGOT, SGPT, Trop I, ECG & Chest X Ray were included in the study. Serum ferritin level was estimated in study group on day 1 & day 6 of MI attack while only once in control. Serum ferritin was estimated by enzyme linked fluorescent assay on Mini Vidas auto analyzer from Biomerieux. Mean serum ferritin levels at Day-1 was not significantly elevated than controls [58.51 (±18.71) ng/ml in day-1 versus 64.09 (±19.42)]. In contrast serum ferritin levels at Day-6 were significantly elevated than controls [226.68 (±18.71) ng/ml at day-6 versus versus ferritin levels in controls (p < 0.001)]. : In conclusion, our data supports that elevated serum ferritin levels are associated with pathogenesis of AMI.
{"title":"Follow up of serum ferritin levels in myocardial infarction in Indian males","authors":"Shikha Agarwal, Praveen Sablania","doi":"10.18231/j.pjms.2023.111","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.111","url":null,"abstract":"National health & nutritional examination survey, 1988-1994, first time reported a significant positive association in iron storage & heart disease risk. Due to the scarcity of this type of study in India, we did this study to find out the relation of serum ferritin with MIThe current study attempts to evaluation association of ferritin levels at the onset of AMI & at 6 day of follow up of subjects. A total of 39 male patients who were confirmed of having MI on the basis of lipid profile, CKMB, SGOT, SGPT, Trop I, ECG & Chest X Ray were included in the study. Serum ferritin level was estimated in study group on day 1 & day 6 of MI attack while only once in control. Serum ferritin was estimated by enzyme linked fluorescent assay on Mini Vidas auto analyzer from Biomerieux. Mean serum ferritin levels at Day-1 was not significantly elevated than controls [58.51 (±18.71) ng/ml in day-1 versus 64.09 (±19.42)]. In contrast serum ferritin levels at Day-6 were significantly elevated than controls [226.68 (±18.71) ng/ml at day-6 versus versus ferritin levels in controls (p < 0.001)]. : In conclusion, our data supports that elevated serum ferritin levels are associated with pathogenesis of AMI.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"12 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138970544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.110
Saqib Rishi, Shaika Farooq, Tabinda Farooq
Subcutaneous mycosis includes a heterogeneous group of fungal infections that develop at the site of transcutaneous trauma. A rise in surviving population of individuals with co-morbidities together with lapses in infection control practices especially in rural India has led to emergence of myriad species of fungi causing such infections in recent years. This poses a diagnostic challenge to the clinicians. We therefore felt a need to study the mycological profile of subcutaneous tissue biopsies suspected of fungal etiology in our hospital setup. This was a Retrospective cross-sectional observational study conducted for a period of 4 years from Jan 2015 to Jan 2019 in the Department of microbiology, Government medical College Srinagar. A total of 148 specimens of subcutaneous tissue biopsies of patients suspected of localized fungal Infection were processed by microscopy and culture for fungi. Among a total of 148 subcutaneous tissue biopsy samples 76 (51%) were positive for fungi on KOH and culture. Mycological profile revealed that majority of fungi were Dermatophytes (n=22; 29%) and Yeasts (n=21; 28%). Third most common causative fungi isolated were Chromoblastomycetes (n=8; 11%), Phaeohyphomycetes (n=8;11%) and Aspergilli (n=8;11 %) comprising, A.fumigatus (n=11) and A.terreus (n=03), followed by Hyalohypomycetes (n=4;5%), sporotrichosis (n=3;4%) and Zygomycetes (n=4 ;5.3%). : Dermatophytes and yeasts are emerging subcutaneous fungal infections. Active surveillance for all types of fungal infections should be done at all levels to address knowledge gaps that exist in etiology, pathogenesis and manifestations of fungal diseases of skin and subcutaneous tissue.
{"title":"Mycological profile of subcutaneous skin biopsy samples in suspected subcutaneous mycosis, Are we missing some fungi? A tertiary care hospital based study","authors":"Saqib Rishi, Shaika Farooq, Tabinda Farooq","doi":"10.18231/j.pjms.2023.110","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.110","url":null,"abstract":"Subcutaneous mycosis includes a heterogeneous group of fungal infections that develop at the site of transcutaneous trauma. A rise in surviving population of individuals with co-morbidities together with lapses in infection control practices especially in rural India has led to emergence of myriad species of fungi causing such infections in recent years. This poses a diagnostic challenge to the clinicians. We therefore felt a need to study the mycological profile of subcutaneous tissue biopsies suspected of fungal etiology in our hospital setup. This was a Retrospective cross-sectional observational study conducted for a period of 4 years from Jan 2015 to Jan 2019 in the Department of microbiology, Government medical College Srinagar. A total of 148 specimens of subcutaneous tissue biopsies of patients suspected of localized fungal Infection were processed by microscopy and culture for fungi. Among a total of 148 subcutaneous tissue biopsy samples 76 (51%) were positive for fungi on KOH and culture. Mycological profile revealed that majority of fungi were Dermatophytes (n=22; 29%) and Yeasts (n=21; 28%). Third most common causative fungi isolated were Chromoblastomycetes (n=8; 11%), Phaeohyphomycetes (n=8;11%) and Aspergilli (n=8;11 %) comprising, A.fumigatus (n=11) and A.terreus (n=03), followed by Hyalohypomycetes (n=4;5%), sporotrichosis (n=3;4%) and Zygomycetes (n=4 ;5.3%). : Dermatophytes and yeasts are emerging subcutaneous fungal infections. Active surveillance for all types of fungal infections should be done at all levels to address knowledge gaps that exist in etiology, pathogenesis and manifestations of fungal diseases of skin and subcutaneous tissue.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"21 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.146
Malini M, Meghana Cr, Amita K, Smitha N
ABO blood group has been divulged as a risk factor for perceptible diseased states. The ABO blood group differences may put a patient at specific risk according to their inherited antigens among the obstetrical syndromes like Intrauterine growth restriction, Pre-eclampsia and pre-term labour. Studies conducted have shown Group O individuals had lowest plasma von Willebrand factor and non O group had elevated level of this factor which showed increased thrombotic risk among these individuals. The earlier studies conducted have focused only on preeclampsia but not on other complications of pregnancy and the data available is scarce. The study aims to determine whether maternal ABO blood groups contribute to adverse pregnancy outcomes especially in this part of the country.The study was conducted on 50 pregnant women who were having complications of pregnancy including preeclampsia (PE), cases of Pregnancy induced hypertension (PIH), Gestational Diabetes mellitus (GDM) were considered as study cases and 50 pregnant women with normal pregnancy without any complications were categorized as controls. The study was conducted for a period of 6 months among patients attending Obstetrics and Gynecology department of Adichunchanagiri hospital selected based on convenience sampling procedure. Maternal ABO Blood group of the subjects were determined by Haemagglutination technique.Relationship between maternal ABO Blood group and Pregnancy complications (PE, PIH.GDM) was estimated by calculating odds ratio from logistic regression models using Blood Group O as a reference group and p – value of < 0.05 was considered as statistically significant. The results of the present study have found that maternal AB blood group was highest among preeclampsia and PIH category of cases.The present study conducted have found maternal AB blood group was highest among PIH and preeclampsia category of casesFrom the study conducted we want to conclude non-O blood group had the highest risk compared to O Blood group among pregnancy complications.
ABO 血型被认为是可感知疾病状态的风险因素。ABO 血型的差异会根据患者的遗传抗原，使其在宫内发育受限、子痫前期和早产等产科综合症中面临特定风险。研究表明，O 组患者的血浆中冯-威廉因子含量最低，而非 O 组患者的血浆中冯-威廉因子含量较高，这表明这些患者的血栓风险增加。早期的研究只关注子痫前期，而没有关注妊娠期的其他并发症，而且可用数据很少。这项研究以 50 名患有妊娠并发症（包括子痫前期（PE）、妊娠高血压（PIH）、妊娠糖尿病（GDM））的孕妇为研究病例，50 名无任何并发症的正常妊娠孕妇为对照组。研究在阿迪春查纳吉里医院妇产科就诊的患者中进行，为期 6 个月，采用方便抽样程序。母体 ABO 血型与妊娠并发症（PE、PIH、GDM）之间的关系是通过以 O 型血为参照组的逻辑回归模型计算出的几率来估算的，P 值小于 0.05 视为具有统计学意义。本研究结果发现，在子痫前期和 PIH 类病例中，母体 AB 血型的风险最高。
{"title":"Relationship between Maternal ABO Blood group and pregnancy complications of adichunchanagiri hospital B.G Nagara -A cross sectional study","authors":"Malini M, Meghana Cr, Amita K, Smitha N","doi":"10.18231/j.pjms.2023.146","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.146","url":null,"abstract":"ABO blood group has been divulged as a risk factor for perceptible diseased states. The ABO blood group differences may put a patient at specific risk according to their inherited antigens among the obstetrical syndromes like Intrauterine growth restriction, Pre-eclampsia and pre-term labour. Studies conducted have shown Group O individuals had lowest plasma von Willebrand factor and non O group had elevated level of this factor which showed increased thrombotic risk among these individuals. The earlier studies conducted have focused only on preeclampsia but not on other complications of pregnancy and the data available is scarce. The study aims to determine whether maternal ABO blood groups contribute to adverse pregnancy outcomes especially in this part of the country.The study was conducted on 50 pregnant women who were having complications of pregnancy including preeclampsia (PE), cases of Pregnancy induced hypertension (PIH), Gestational Diabetes mellitus (GDM) were considered as study cases and 50 pregnant women with normal pregnancy without any complications were categorized as controls. The study was conducted for a period of 6 months among patients attending Obstetrics and Gynecology department of Adichunchanagiri hospital selected based on convenience sampling procedure. Maternal ABO Blood group of the subjects were determined by Haemagglutination technique.Relationship between maternal ABO Blood group and Pregnancy complications (PE, PIH.GDM) was estimated by calculating odds ratio from logistic regression models using Blood Group O as a reference group and p – value of < 0.05 was considered as statistically significant. The results of the present study have found that maternal AB blood group was highest among preeclampsia and PIH category of cases.The present study conducted have found maternal AB blood group was highest among PIH and preeclampsia category of casesFrom the study conducted we want to conclude non-O blood group had the highest risk compared to O Blood group among pregnancy complications.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"342 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.108
Kusuma Gowdra Rangappa, Ambica Rangaiah
Intestinal carriage of carbapenem-resistant and (CREK) plays an important role in the epidemiology of carbapenemase producers. Less is known about the carriage of CREK among the outpatients when compared to carriage among patients in Intensive Care Units. (ICU) Therefore the present study was performed to detect colonization of CREK among ICU patients and outpatients of our tertiary care hospital. Rectal swabs from ICU patients and stool specimens from outpatients were collected. Identification and antimicrobial susceptibility were performed using Vitek 2 compact system. Screening for CREK was done by two methods and confirmed for carbapenemase production by mCIM. Carbapenemase genes were detected by multiplex polymerase chain reaction.Overall 460 patients were analyzed for the intestinal carriage of CREK, 230 patients each from ICU and outpatients. 10.4% of outpatients and 26% of ICU patients found positive for CREK carriage. The target genes for carbapenemase production found in 78/86 CREK isolates. The majority of isolates 50/78 (64%) harbored beta-lactamase (bla) NDM gene followed by blaOXA-48 like in 18/78 (23%) isolates and 10/78(12%) isolates had both the genes.Detection of carbapenem-resistant genes in commensal flora of the gut is worrisome. Building proper awareness about the use of antimicrobials in the community and strict surveillance systems to monitor these resistant bacteria in humans, food-producing animals, and the environment could all help to reduce the colonization of CREK among healthy individuals. Implementation of strict infection control measures and prudent use of carbapenems can help to limit the spread of these superbugs in the hospital.
{"title":"Intestinal carriage and molecular characteristics of carbapenem resistant Escherichia coli and Klebsiella pneumoniae among patients in intensive care units and outpatients in a tertiary care hospital","authors":"Kusuma Gowdra Rangappa, Ambica Rangaiah","doi":"10.18231/j.pjms.2023.108","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.108","url":null,"abstract":"Intestinal carriage of carbapenem-resistant and (CREK) plays an important role in the epidemiology of carbapenemase producers. Less is known about the carriage of CREK among the outpatients when compared to carriage among patients in Intensive Care Units. (ICU) Therefore the present study was performed to detect colonization of CREK among ICU patients and outpatients of our tertiary care hospital. Rectal swabs from ICU patients and stool specimens from outpatients were collected. Identification and antimicrobial susceptibility were performed using Vitek 2 compact system. Screening for CREK was done by two methods and confirmed for carbapenemase production by mCIM. Carbapenemase genes were detected by multiplex polymerase chain reaction.Overall 460 patients were analyzed for the intestinal carriage of CREK, 230 patients each from ICU and outpatients. 10.4% of outpatients and 26% of ICU patients found positive for CREK carriage. The target genes for carbapenemase production found in 78/86 CREK isolates. The majority of isolates 50/78 (64%) harbored beta-lactamase (bla) NDM gene followed by blaOXA-48 like in 18/78 (23%) isolates and 10/78(12%) isolates had both the genes.Detection of carbapenem-resistant genes in commensal flora of the gut is worrisome. Building proper awareness about the use of antimicrobials in the community and strict surveillance systems to monitor these resistant bacteria in humans, food-producing animals, and the environment could all help to reduce the colonization of CREK among healthy individuals. Implementation of strict infection control measures and prudent use of carbapenems can help to limit the spread of these superbugs in the hospital.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"82 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.102
H. Salankar
{"title":"Electives: A welcome innovation in medical education","authors":"H. Salankar","doi":"10.18231/j.pjms.2023.102","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.102","url":null,"abstract":"","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"101 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.148
Sahiba Deepinder Sachdev, S. Gawande, A. Faye, S. Bhave, V. Kirpekar, Tadke Rahul
: Self -stigma occurs when a person accepts the negative attitude towards them, then internalize and apply belief to themselves. Self-esteem is individual’s subjective evaluation of their own worth. Self-stigma and self-esteem affects a person’s perception about themselves and the society surrounding them which plays an important role in treatment. It is most commonly affected in people diagnosed with psychiatric disorders.The aim was to study self-stigma and self-esteem in patients with anxiety and depression.After permission from Institutional ethics committee, semi-structured proforma, Internalized Stigma of Mental Illness Inventory-9 and Rosenberg’s Self Esteem Scale was used to assess 50 consecutive participants diagnosed with anxiety and depression according to DSM-5 criteria. Participants satisfying the inclusion and exclusion criteria were included in the study. The data collected was tabulated and analysed statistically and results and conclusions were drawn by using chi-square test, a p-value of <0.05 was considered significant.Mean age of participants was 38.88 years with 64% females, majority being married, predominantly from urban background having education of at least secondary school certificate.19 participants were diagnosed with anxiety while 31 had depression.56% of the participants had high self-stigma and 54% participants had low self-esteem. There wasn’t any significant difference in percentages of high self-stigma and low self-esteem when compared between anxiety disorders and in depression. There were no significant socio-demographic or clinical correlates relating to self- stigma and self-esteem according to this study. It was observed that both high self-stigma and low self-esteem was significantly high in psychiatric patients. It was seen that low self- esteem was associated with high self-stigma and high self-esteem was associated with low self-stigma. Hence, steps must be taken to psycho-educate the patient and their family members in order to reduce self-stigma and help in increasing their self-esteem.
{"title":"Study of self- stigma and self -esteem in patients with anxiety and depression","authors":"Sahiba Deepinder Sachdev, S. Gawande, A. Faye, S. Bhave, V. Kirpekar, Tadke Rahul","doi":"10.18231/j.pjms.2023.148","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.148","url":null,"abstract":": Self -stigma occurs when a person accepts the negative attitude towards them, then internalize and apply belief to themselves. Self-esteem is individual’s subjective evaluation of their own worth. Self-stigma and self-esteem affects a person’s perception about themselves and the society surrounding them which plays an important role in treatment. It is most commonly affected in people diagnosed with psychiatric disorders.The aim was to study self-stigma and self-esteem in patients with anxiety and depression.After permission from Institutional ethics committee, semi-structured proforma, Internalized Stigma of Mental Illness Inventory-9 and Rosenberg’s Self Esteem Scale was used to assess 50 consecutive participants diagnosed with anxiety and depression according to DSM-5 criteria. Participants satisfying the inclusion and exclusion criteria were included in the study. The data collected was tabulated and analysed statistically and results and conclusions were drawn by using chi-square test, a p-value of <0.05 was considered significant.Mean age of participants was 38.88 years with 64% females, majority being married, predominantly from urban background having education of at least secondary school certificate.19 participants were diagnosed with anxiety while 31 had depression.56% of the participants had high self-stigma and 54% participants had low self-esteem. There wasn’t any significant difference in percentages of high self-stigma and low self-esteem when compared between anxiety disorders and in depression. There were no significant socio-demographic or clinical correlates relating to self- stigma and self-esteem according to this study. It was observed that both high self-stigma and low self-esteem was significantly high in psychiatric patients. It was seen that low self- esteem was associated with high self-stigma and high self-esteem was associated with low self-stigma. Hence, steps must be taken to psycho-educate the patient and their family members in order to reduce self-stigma and help in increasing their self-esteem.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"18 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.130
R. K, Sarita Jaiswal
Fetaldevelopment and growth in uterus is most critical. Most commonly used indicator is birth weight for determining well-being of infant. Body mass index (BMI) of mother before pregnancy, pregnancy weight gain, and other factors related to behavior, socio-cultural as well as genetics influence the birth weight. To study effect of pre-pregnancy BMI and gestational weight gain on fetal outcomeHospital-based follow-up study was carried out among 189 antenatal women. Gestational age, weight, height, BMI and fetal growth were recorded. Regular sonography was carried out to rule out fetal congenital abnormalities and fetal well-being. Daily fetal movement count, fetal heart rate monitoring was carried out daily. Estimation of the “total pregnancy weight gain” was done by subtracting last measured weight before delivery from weight recorded at first visit in first trimester. Birth weight of the neonate was recorded within 24 hours of delivery. BMI before pregnanacy was normal in Majority (75.1%). Underweight women earlier to conception had either normal Gestational weight gain (GWG) or less than normal GWG. Their babies also had significantly low average birth weight compared to either normal weight females or overweight and obese before conception. Overweight and obese females before conception had higher incidence of gestational diabetes (GDM) and cesarean section. Normal weight females before conception had higher incidence of Pregnancy induced hypertension.Being underweight before conception is a risk factor for low birth weight babies whereas being overweight and obese before pregnancy is a risk factor for GDM.
{"title":"Effect of pre-pregnancy body mass index and gestational weight gain on fetal outcome","authors":"R. K, Sarita Jaiswal","doi":"10.18231/j.pjms.2023.130","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.130","url":null,"abstract":"Fetaldevelopment and growth in uterus is most critical. Most commonly used indicator is birth weight for determining well-being of infant. Body mass index (BMI) of mother before pregnancy, pregnancy weight gain, and other factors related to behavior, socio-cultural as well as genetics influence the birth weight. To study effect of pre-pregnancy BMI and gestational weight gain on fetal outcomeHospital-based follow-up study was carried out among 189 antenatal women. Gestational age, weight, height, BMI and fetal growth were recorded. Regular sonography was carried out to rule out fetal congenital abnormalities and fetal well-being. Daily fetal movement count, fetal heart rate monitoring was carried out daily. Estimation of the “total pregnancy weight gain” was done by subtracting last measured weight before delivery from weight recorded at first visit in first trimester. Birth weight of the neonate was recorded within 24 hours of delivery. BMI before pregnanacy was normal in Majority (75.1%). Underweight women earlier to conception had either normal Gestational weight gain (GWG) or less than normal GWG. Their babies also had significantly low average birth weight compared to either normal weight females or overweight and obese before conception. Overweight and obese females before conception had higher incidence of gestational diabetes (GDM) and cesarean section. Normal weight females before conception had higher incidence of Pregnancy induced hypertension.Being underweight before conception is a risk factor for low birth weight babies whereas being overweight and obese before pregnancy is a risk factor for GDM.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.pjms.2023.117
Sristi Ganguly, Ipsita Jena, N. Soren
With recent advances for a chronic disease like thalassemia, where lifelong management is required, the quality of life, not just survival gains important. Owing to high burden of thalassemia in Odisha, this study analyses the quality of life in pediatric beta thalassemia major and the factors influencing the same. This was a hospital based cross-sectional study done in a tertiary care hospital, Cuttack during September 2019 to January 2020. Children aged 5-14 years, diagnosed with beta-thalassemia major with regular blood transfusion, were subjected to modified SF-36 questionnaire to assess the quality of life in total and domains- General health , Physical health , Social activities , Limitation of activities, Educational , Psychological and Family aspect. Score above 50 considered as good. Data analysed using SPSS 18.0.Statistical significance was assessed by ANOVA and Chi-square test. Among 200 cases studied, majority (70.5%) had poor score, with mean being 49.19+6.53. In terms of domain, family aspect led (62.0+ 15.60), followed by limitation of activities(58.25+27.69), psychological aspect (51.75+ 12.47), physical health (50.85+14.60), educational aspect (41.92+ 19.294), general health (41.40+12.32) and social aspect was 38.17+ 24.20.A significant association was noted between good quality of life and male gender (p-0.004), mother’s occupation (p-0.013), number of children (p-0.001), higher serum ferritin level (p<0.05) and blood transfusion frequency (p-0.015) in the study population. Considering the poor quality of life in children with thalassemia major, there is urgent need to focus on holistic approach towards management incorporating educational, emotional and physical rehabilitation, to ensure their productivity in the society.
{"title":"Quality of life in children aged 5- 14 years with beta thalessemia major","authors":"Sristi Ganguly, Ipsita Jena, N. Soren","doi":"10.18231/j.pjms.2023.117","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.117","url":null,"abstract":"With recent advances for a chronic disease like thalassemia, where lifelong management is required, the quality of life, not just survival gains important. Owing to high burden of thalassemia in Odisha, this study analyses the quality of life in pediatric beta thalassemia major and the factors influencing the same. This was a hospital based cross-sectional study done in a tertiary care hospital, Cuttack during September 2019 to January 2020. Children aged 5-14 years, diagnosed with beta-thalassemia major with regular blood transfusion, were subjected to modified SF-36 questionnaire to assess the quality of life in total and domains- General health , Physical health , Social activities , Limitation of activities, Educational , Psychological and Family aspect. Score above 50 considered as good. Data analysed using SPSS 18.0.Statistical significance was assessed by ANOVA and Chi-square test. Among 200 cases studied, majority (70.5%) had poor score, with mean being 49.19+6.53. In terms of domain, family aspect led (62.0+ 15.60), followed by limitation of activities(58.25+27.69), psychological aspect (51.75+ 12.47), physical health (50.85+14.60), educational aspect (41.92+ 19.294), general health (41.40+12.32) and social aspect was 38.17+ 24.20.A significant association was noted between good quality of life and male gender (p-0.004), mother’s occupation (p-0.013), number of children (p-0.001), higher serum ferritin level (p<0.05) and blood transfusion frequency (p-0.015) in the study population. Considering the poor quality of life in children with thalassemia major, there is urgent need to focus on holistic approach towards management incorporating educational, emotional and physical rehabilitation, to ensure their productivity in the society.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"21 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: Birth asphyxia is defined by the World Health Organization as the failure to initiate and sustain breathing at birth. Etiological factors include maternal factors like hypertension, chorioamnionitis, diabetes, maternal pulmonary or cardiac disorders, placental factors like abnormal placentation, abruption, infarction, hydrops, uterine rupture, umbilical cord prolapse, entanglement, true knot, compression, abnormalities of blood vessels, fetal factors like anemia, cardiomyopathy, infections, hydrops, neonatal factors like cyanotic congenital heart disease, persistent pulmonary hypertension of the newborn, respiratory failure due to meconium aspiration syndrome, congenital pneumonia, pneumothorax etc.: To study the contributing factors, complications and immediate outcome of birth asphyxia in a tertiary care centre in Assam.: It was a prospective observational study carried out in NICU, Gauhati Medical College & Hospital, Guwahati, Assam. The study included clinical profile of 200 cases of birth asphyxia admitted to the above center during period of one year starting from 1st of August 2021 to 31 July 2022.: In our study, out of 200 neonates, 102(51%) were male and 98(49%) were female. 161 cases (80.5%) were term.115 mothers (57.5% were primigravida and 85 mothers (42.5%) were multigravida. Various antenatal contributing factors were found to be meconium stained liquor (68%), anemia (57%), pregnancy induced hypertension (15%), prolonged labor (28.5%), fever(5%), antepartum haemorrhage (5.5%), chorioamnionitis (5%).Various complications of birth asphyxia observed in the study were hyperbilirubinemia 76 cases (38%), hypocalcemia 46 cases (23%), shock 31 cases (15.5%), DIC(13%), meconium aspiration syndrome 24 cases (12%), hypoglycemia 15 cases(7.5%),sepsis 13 cases (6.5%), apnea 14 cases (7%), Necrotising Enterocolitis 6 cases (3%), AKI 120 cases (60%) and the total mortality percentage was 26%.: Birth asphyxia is a leading cause of mortality among the newborn. The contributing factors needs to be addressed at the earliest to decrease the mortality and morbidity due to birth asphyxia.
{"title":"Contributing factors, complications and immediate outcome of birth asphyxia in a tertiary care centre in Assam","authors":"Himadri Das, G. Medhi, Priyanki Devi, Bhanita Deka, Diganta Barman, Monalisa Bhoktiari","doi":"10.18231/j.pjms.2023.106","DOIUrl":"https://doi.org/10.18231/j.pjms.2023.106","url":null,"abstract":": Birth asphyxia is defined by the World Health Organization as the failure to initiate and sustain breathing at birth. Etiological factors include maternal factors like hypertension, chorioamnionitis, diabetes, maternal pulmonary or cardiac disorders, placental factors like abnormal placentation, abruption, infarction, hydrops, uterine rupture, umbilical cord prolapse, entanglement, true knot, compression, abnormalities of blood vessels, fetal factors like anemia, cardiomyopathy, infections, hydrops, neonatal factors like cyanotic congenital heart disease, persistent pulmonary hypertension of the newborn, respiratory failure due to meconium aspiration syndrome, congenital pneumonia, pneumothorax etc.: To study the contributing factors, complications and immediate outcome of birth asphyxia in a tertiary care centre in Assam.: It was a prospective observational study carried out in NICU, Gauhati Medical College & Hospital, Guwahati, Assam. The study included clinical profile of 200 cases of birth asphyxia admitted to the above center during period of one year starting from 1st of August 2021 to 31 July 2022.: In our study, out of 200 neonates, 102(51%) were male and 98(49%) were female. 161 cases (80.5%) were term.115 mothers (57.5% were primigravida and 85 mothers (42.5%) were multigravida. Various antenatal contributing factors were found to be meconium stained liquor (68%), anemia (57%), pregnancy induced hypertension (15%), prolonged labor (28.5%), fever(5%), antepartum haemorrhage (5.5%), chorioamnionitis (5%).Various complications of birth asphyxia observed in the study were hyperbilirubinemia 76 cases (38%), hypocalcemia 46 cases (23%), shock 31 cases (15.5%), DIC(13%), meconium aspiration syndrome 24 cases (12%), hypoglycemia 15 cases(7.5%),sepsis 13 cases (6.5%), apnea 14 cases (7%), Necrotising Enterocolitis 6 cases (3%), AKI 120 cases (60%) and the total mortality percentage was 26%.: Birth asphyxia is a leading cause of mortality among the newborn. The contributing factors needs to be addressed at the earliest to decrease the mortality and morbidity due to birth asphyxia.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"182 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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